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Tracking a High-Tech Transition--How technology is powering Guangdong’s manufacturing transformation
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作者 HU FAN 《ChinAfrica》 2026年第1期30-32,共3页
The moment a media delegation from the Republic of the Congo arrived at the Othello Kitchenware Museum on 18 November 2025,they were greeted with a vivid show of Guangdong’s industrial strength.Standing before them w... The moment a media delegation from the Republic of the Congo arrived at the Othello Kitchenware Museum on 18 November 2025,they were greeted with a vivid show of Guangdong’s industrial strength.Standing before them was not a typical exhibition hall,but a building shaped like a gleaming stainless-steel cooking pot. 展开更多
关键词 othello kitchenware museum TECHNOLOGY industrial strength high tech transition guangdong manufacturing transformation
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Pressure-Driven Semiconductor-to-Metal, Magnetic, and Structural Transitions in the Ferrimagnetic Semiconductor Mn_(3)Si_(2)Te_(6)
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作者 Jun Hou Hanming Ma +11 位作者 Qiangwei Yin Xiutong Deng Pengfei Shan Zhaorong Yang Yoshiya Uwatoko Xiaohui Yu Xiaoli Ma Youguo Shi Xiaoli Dong Hechang Lei Jianping Sun Jinguang Cheng 《Chinese Physics Letters》 2025年第5期161-168,共8页
Mn_(3)Si_(2)Te_(6) is a ferrimagnetic nodal-line semiconductor with colossal angular magnetoresistance at ambient pressure.In this work,we investigated the effect of hydrostatic pressure on its electrical transport pr... Mn_(3)Si_(2)Te_(6) is a ferrimagnetic nodal-line semiconductor with colossal angular magnetoresistance at ambient pressure.In this work,we investigated the effect of hydrostatic pressure on its electrical transport properties,magnetic transition,and crystal structure by measuring resistivity,DC and AC magnetic susceptibility,and XRD under various pressures up to~20 GPa.Our results confirmed the occurrence of pressure-induced structural transition at P_(c)≈10–12 GPa accompanied by a concurrent drop of room-temperature resistance in Mn_(3)Si_(2)Te_(6).In the low-pressure phase at PP_(c),the sample exhibits a metallic behavior in the whole temperature range and its resistivity exhibits a kink anomaly at T_(M),characteristic of critical scattering around a magnetic transition.Recovery of the Raman spectrum upon decompression indicated that pressure-induced structural transition is reversible without amorphization under hydrostatic pressure conditions.Our present work not only resolves some existing controversial issues but also provides new insights into pressure-driven diverse behaviors of Mn_(3)Si_(2)Te_(6). 展开更多
关键词 structural transition magnetic transition electrical transport properties pressure driven transitions crystal structure colossal angular magnetoresistance hydrostatic pressure resistivitydc ac magnetic susceptibilityand
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High-Pressure Phase Transitions and Mechanisms in Lanthanum Mononitride
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作者 Hao Chen Dan Zhou +1 位作者 Ying Xu Quan Li 《Chinese Physics Letters》 2025年第6期163-169,共7页
A longstanding discrepancy between theoretical predictions and experimental observations on the highpressurestructural transformations of lanthanum mononitride(LaN)has posed challenges for understandingthe behavior of... A longstanding discrepancy between theoretical predictions and experimental observations on the highpressurestructural transformations of lanthanum mononitride(LaN)has posed challenges for understandingthe behavior of heavy transition metal mononitrides.Here,we systematically investigate the structural evolutionof LaN under high pressure using first-principles calculations combined with angle-dispersive synchrotron X-raydiffraction,identifying the phase transition sequence and corresponding phase boundaries.Analyses of energetics,kinetic barriers,and lattice dynamics reveal distinct mechanisms driving these transitions.These results clarifythe structural stability of LaN and offer guidance for studying other heavy transition metal mononitrides withcomplex electronic behavior under extreme conditions. 展开更多
关键词 phase transition sequence understandingthe behavior heavy transition metal mononitridesherewe high pressure phase transitions lanthanum mononitride theoretical predictions lattice dynamics structural stability lanthanum mononitride lan
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New challenges of water disasters:Mechanisms,identification,and risks of abrupt transitions between drought and flood
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作者 Shan-shui Yuan Zi-yan Shi 《Water Science and Engineering》 2025年第3期259-261,共3页
In the context of climate change,the acceleration of the global water cycle has led to the emergence of abrupt transitions between drought and flood events,presenting a new challenge for flood and drought disaster mit... In the context of climate change,the acceleration of the global water cycle has led to the emergence of abrupt transitions between drought and flood events,presenting a new challenge for flood and drought disaster mitigation.Abrupt transitions between drought and flood refer to a phenomenon in which an extreme drought event quickly shifts to an extreme flood event,or vice versa,within a relatively short time span.This phenomenon disrupts the traditional spatiotemporal distribution patterns of water-related disasters,reflecting not only the extreme unevenness in the distribution of water resources but also the rapid alternation of the water cycle's evolution(He et al.,2016).Moreover,due to its suddenness,extremity,and complexity,it poses severe threats to human societies and ecosystems.Scientifically addressing abrupt transitions between drought and flood has thus become a new challenge in flood and drought disaster prevention. 展开更多
关键词 climate changethe FLOOD spatiotemporal distribution patterns abrupt transitions drought flood acceleration global water cycle flood drought disaster mitigationabrupt transitions drought flood climate change abrupt transitions
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Characteristics of phase transitions in dry aligning active matter
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作者 Bing Yang Yanting Wang 《Communications in Theoretical Physics》 2025年第6期223-239,共17页
Active matter is a non-equilibrium condensed system consisting of self-propelled particles capable of converting stored or ambient energy into collective motion.Typical active matter systems include cytoskeleton biopo... Active matter is a non-equilibrium condensed system consisting of self-propelled particles capable of converting stored or ambient energy into collective motion.Typical active matter systems include cytoskeleton biopolymers,swimming bacteria,artificial swimmers,and animal herds.In contrast to wet active matter,dry active matter is an active system characterized by the absence of significant hydrodynamic interactions and conserved momentum.In dry active matter,the role of surrounding fluids is providing viscous friction at low Reynolds numbers and can be neglected at high Reynolds numbers.This review offers a comprehensive overview of recent experimental,computational,and theoretical advances in understanding phase transitions and critical phenomena in dry aligning active matter,including polar particles,self-propelled rods,active nematics,and their chiral counterparts.Various ways of determining phase transition points as well as non-equilibrium phenomena,such as collective motion,cluster formation,and creation and annihilation of topological defects are reviewed. 展开更多
关键词 dry aligning active matter continuous phase transitions discontinuous phase transitions topological phase transitions
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Effect of start cooling temperature on microstructure,crystallographic orientation and ductile-to-brittle transition behavior of high strength steel
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作者 LIU Wen-jian LI Hong-ying +5 位作者 KONG Yao-jie LIU Ji-wen LIU Dan GAO Qing PENG Ning-qi XIONG Xiang-jiang 《Journal of Central South University》 2025年第3期776-788,共13页
The ductile-to-brittle transition temperature(DBTT)of high strength steels can be optimized by tailoring microstructure and crystallographic orientation characteristics,where the start cooling temperature plays a key ... The ductile-to-brittle transition temperature(DBTT)of high strength steels can be optimized by tailoring microstructure and crystallographic orientation characteristics,where the start cooling temperature plays a key role.In this work,X70 steels with different start cooling temperatures were prepared through thermo-mechanical control process.The quasi-polygonal ferrite(QF),granular bainite(GB),bainitic ferrite(BF)and martensite-austenite constituents were formed at the start cooling temperatures of 780℃(C1),740℃(C2)and 700℃(C3).As start cooling temperature decreased,the amount of GB decreased,the microstructure of QF and BF increased.Microstructure characteristics of the three samples,such as high-angle grain boundaries(HAGBs),MA constituents and crystallographic orientation,also varied with the start cooling temperatures.C2 sample had the lowest DBTT value(−86℃)for its highest fraction of HAGBs,highest content of<110>oriented grains and lowest content of<001>oriented grains parallel to TD.The high density of{332}<113>and low density of rotated cube{001}<110>textures also contributed to the best impact toughness of C2 sample.In addition,a modified model was used in this paper to quantitatively predict the approximate DBTT value of steels. 展开更多
关键词 X70 steel start cooling temperature ductile-to-brittle transition martensite-austenite islands crystallographic orientation ductile-to-brittle transition temperature(DBTT) prediction model
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Comprehensive analysis of characteristics of dry-wet events and their transitions in Uttar Pradesh,India
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作者 Shivani Gond Ashish Kumar Agnihotri +1 位作者 Nitesh Gupta P.K.S.Dikshit 《Water Science and Engineering》 2025年第1期59-68,共10页
Understanding the occurrence and characteristics of dry and wet events is crucial for effective disaster prevention,resource management,and risk reduction in vulnerable regions.This study analyzed the spatiotemporal p... Understanding the occurrence and characteristics of dry and wet events is crucial for effective disaster prevention,resource management,and risk reduction in vulnerable regions.This study analyzed the spatiotemporal patterns of dry-wet events and their transition characteristics in Uttar Pradesh,India.The standardized precipitation evapotranspiration index(SPEI)at a monthly timescale was utilized to identify hotspot regions vulnerable to concurrent and frequent dry and wet events and their transitions.The severity,duration,and intensity of dry and wet events were characterized with the run theory over SPEI time series data from 18 synoptic stations in Uttar Pradesh over 48 years(1971-2018),sourced from the Indian Institute of Tropical Meteorology and the India Meteorological Department.Multiple assessment methods were utilized to examine the interaction of these extreme events,considering characteristics such as wet-dry ratio,average transition time,and rapid transition times from wet to dry events and from dry to wet events.Average wet durations ranged from 1.27 to 1.58 months,and average dry durations ranged from 1.29 to 1.82 months.Rapid transition times from dry to wet events ranged from 2.5 to 4.1 months,and those for wet-to-dry events ranged from 2.1 to 5.3 months.The eastern region experienced a significantly high number of dry events,while the western and Bundelkhand regions experienced more intense dry events.In contrast,the eastern region had intense wet events.This research on the occurrence of dry-wet events and their transitions can provide valuable insights for government decision-making and disaster prevention and reduction efforts. 展开更多
关键词 Climate extreme SPEI Dry and wet event Average transition time Rapid transition time
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Challenges in the Transition and Transfer of Young Adults with Congenital Heart Disease in Latin America and the Caribbean: The “Timeliness Principle”
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作者 John J.Araujo 《Congenital Heart Disease》 2025年第1期61-75,共15页
Today,more than 90%of children who are born with congenital heart disease survive and reach adulthood,especially in developed countries.Consequently,the population of adults with congenital heart disease has increased... Today,more than 90%of children who are born with congenital heart disease survive and reach adulthood,especially in developed countries.Consequently,the population of adults with congenital heart disease has increased signiffcantly over the last few decades.In Latin America and the Caribbean countries,this same scenario is occurring at an accelerated pace.Loss to follow-up is a global problem in adults with congenital heart disease,ranging from 30–60%.In Latin America and Caribbean countries,it is estimated that less than 10%of adults with congenital heart disease are being followed.The small number of specialists and adult congenital heart disease specialized centers,as well as virtually nonexistent transition and transfer programs,are some of the reasons for this.This article is a narrative review of the current status of the transition and transfer of young adults with congenital heart disease,with a special focus on Latin America and Caribbean countries.It describes the general concepts of transition and transfer,analyzes barriers and,ffnally,presents specialized care alternatives that would reduce losses and improve this population’s care. 展开更多
关键词 Adults with congenital heart disease transition and transfer loss to follow-up transition program Latin America and the Caribbean
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Characteristics of the Epidemiological Transition from 1990 to 2020 in Côte d’Ivoire
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作者 Guillaume Okoubo Daniel Kouadio Ekra +1 位作者 Ekissi Orsot Tetchi Calixte Guehi 《Open Journal of Epidemiology》 2025年第1期76-87,共12页
Background: Since it was theorised by Abdel Omran in 1971, the epidemiological transition has been well documented in Latin America, Asia and even increasingly in Africa south of the Sahara. According to this theory, ... Background: Since it was theorised by Abdel Omran in 1971, the epidemiological transition has been well documented in Latin America, Asia and even increasingly in Africa south of the Sahara. According to this theory, sub-Saharan Africa is in the first phase of development corresponding to the “age of plague and famine”. Given the health statistics currently available, more and more low- and middle-income countries, including those in sub-Saharan Africa, are experiencing an increase in mortality and the economic impact associated with non-communicable diseases. Côte d’Ivoire is one of the countries in sub-Saharan Africa where non-communicable diseases are currently on the rise. Despite the significant changes observed over the last decades, few studies have been carried out on the epidemiological transition in Côte d’Ivoire. It therefore seemed necessary to examine the changes in patterns of disease occurrence and causes of death in Côte d’Ivoire. Objectives: This work aimed to determine the reality of the epidemiological transition in Côte d’Ivoire and characterize its facies from 1990 to 2020. Methods: A literature review was carried out using PubMed, Medline, Google Scholar, Google, institutional websites (WHO, World Bank), university library websites and institutional reports from Côte d’Ivoire. The indicators sought were mortality, morbidity, life expectancy and fertility. Results: Mortality fell overall from 13.88‰ to 9.70‰, with variations linked to cyclical situations. Life expectancy rose by 52.6 to 59.03 years, although it is still below 60. Fertility has fallen from 6.3 to 4.5 children. There is a general downward trend in morbidity due to communicable diseases between 2009 and 2019, followed by an increase in non-communicable diseases. Conclusion: Côte d’Ivoire is undergoing an original and complex epidemiological transition that needs to be taken into account in health policies and strategies. 展开更多
关键词 Epidemiological transition Omran’s Theory of Epidemiological transition Communicable Diseases Non-Communicable Diseases Côte d’Ivoire
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Pressure-induced metallization and Lifshitz transition in quasi-one-dimensional TiSe_(3)single crystal
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作者 Zhenhai Yu Yunguan Ye +14 位作者 Pengtao Yang Yiming Wang Liucheng Chen Chenglin Li Jian Yuan Ziyi Liu Zhiwei Shen Shaojie Wang Mingtao Li Chaoyang Chu Xia Wang Jun Li Lin Wang Wenge Yang Yanfeng Guo 《Chinese Physics B》 2025年第8期314-322,共9页
The transition metal trichalcogenides(TMTs)with quasi-one-dimensional(quasi-1D)layered crystal structure represent a unique platform to explore intriguing physical properties.Herein,we report the successful growth of ... The transition metal trichalcogenides(TMTs)with quasi-one-dimensional(quasi-1D)layered crystal structure represent a unique platform to explore intriguing physical properties.Herein,we report the successful growth of a new TMT TiSe_(3)single crystal by using a high-pressure and high-temperature technique.The crystal structure of TiSe_(3)was determined by measuring the single-crystal x-ray diffraction and selected area electron diffraction.The 1D chain-like structure along the b-axis is formed by the TiSe_(6)prisms which share their tops and bottoms with each other.TiSe_(3)is a narrow band gap semiconductor with electron-type carriers under ambient conditions identified by the electrical and Hall effect measurements.It exhibits a pressure-induced semiconductor-to-metal transition around 4 GPa.As the pressure further increases to~6 GPa,a pressure-induced Lifshitz transition occurs,as indicated by the electrical transport measurements,high-pressure crystal structure characterizations,and electronic band structure calculations. 展开更多
关键词 high-pressure synthesis transition metal trichalcogenides quasi-one-dimensional layered crystal structure Lifshitz transition
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Editor’s introduction to the special issue on green digital finance and energy transition,and FinTech and market analysis
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作者 Farhad Taghizadeh‑Hesary Muhammad Kamran Khan +1 位作者 Bing Xu Gang Kou 《Financial Innovation》 2025年第1期3258-3262,共5页
The 52nd issue of Financial Innovation(FIN),Volume 11,No.4(2025),features 19 papers that can be classified into two main themes:the Special Issue on Green Digital Finance and Energy Transition,and FinTech and Market A... The 52nd issue of Financial Innovation(FIN),Volume 11,No.4(2025),features 19 papers that can be classified into two main themes:the Special Issue on Green Digital Finance and Energy Transition,and FinTech and Market Analysis. 展开更多
关键词 energy transitionand fintech fintech market analysis market analysis green digital finance energy transition
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Attosecond Time Delay in Bound-Bound Transitions Probed by Fano Resonances
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作者 Zhigang Zheng Li Wang +5 位作者 Di Wang Mingyue Wang Fan Xiao Jing Zhao Xiaowei Wang Zengxiu Zhao 《Chinese Physics Letters》 2025年第9期23-27,共5页
This letter presents a method for probing the attosecond time delay between two radiatively resonant transitions from Fano structures,which arise from interference between the extreme ultraviolet free induction decay(... This letter presents a method for probing the attosecond time delay between two radiatively resonant transitions from Fano structures,which arise from interference between the extreme ultraviolet free induction decay(XFID)emission and high-order harmonics.The ellipticity dependence of the Ne^(+)XFID yield confirms that the ionic excited-state populations originate from inelastic recollision between tunneling electrons and parent ions.Subsequent extraction of relative phases from Fano structures enables the determination of the time delay(~22 as)between the two decay pathways.This work provides an experimental approach to probe the attosecond time delay between different XFID channels and contributes to a deeper understanding of the tunneling-plusrescattering model in strong laser fields. 展开更多
关键词 radiatively resonant transitions extraction relative phases parent ionssubsequent fano structureswhich bound bound transitions tunneling electrons inelastic recollision fano structures
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Neutron Spin Resonance near a Lifshitz Transition in Overdoped Ba_(0.4)K_(0.6)Fe_(2)As_(2)
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作者 Yang Li Dingsong Wu +11 位作者 Yingjie Shu Bo Liu Uwe Stuhr Guochu Deng Anton PJStamp Lin Zhao Xingjiang Zhou Shiliang Li Amit Pokhriyal Haranath Ghosh Wenshan Hong Huiqian Luo 《Chinese Physics Letters》 2025年第6期255-260,共6页
Elucidating the relationship between spin excitations and fermiology is essential for clarifying the pairing mechanism in iron-based superconductors(FeSCs).Here,we report inelastic neutron scattering results on the ho... Elucidating the relationship between spin excitations and fermiology is essential for clarifying the pairing mechanism in iron-based superconductors(FeSCs).Here,we report inelastic neutron scattering results on the hole overdoped Ba_(0.4)K_(0.6)Fe_(2)As_(2) near a Lifshitz transition,where the electron pocket at M point is nearly replaced by four hole pockets.In the normal state,the spin excitations is observed at incommensurate wave vectors with a chimney-like dispersion.By cooling down to the superconducting state,a neutron spin resonance mode emerges with a peak energy of Er=14-15 meV,weakly modulated along the L-direction.The incommensurability notably increases at low energies,giving rise to downward dispersions of the resonance mode.This behavior contrasts sharply with the upward dispersions of resonance observed in optimally doped Ba_(0.67)K_(0.33)Fe_(2)As_(2) contributed by the hole to electron scattering,but resembles those in KFe_(2)As_(2) and KCa_(2)Fe_(4)As_(4)F_(2) where the fermiology is dominated by hole pockets.These results highlight the critical role of electronic structure modifications near the Fermi level,especially in governing interband scattering under imperfect nesting conditions,which fundamentally shape the spin dynamics of FeSCs. 展开更多
关键词 elucidating relationship spin excitations fermiology pairing mechanism inelastic neutron scattering lifshitz transitionwhere cooling down Lifshitz transition hole overdoped neutron spin resonance
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Complete Universal Scaling of First-Order Phase Transitions in the Two-Dimensional Ising Model
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作者 Yuxiang Zhang Fan Zhong 《Chinese Physics Letters》 2025年第9期1-6,共6页
Phase transitions,as one of the most intriguing phenomena in nature,are divided into first-order phase transitions(FOPTs)and continuous ones in current classification.While the latter shows striking phenomena of scali... Phase transitions,as one of the most intriguing phenomena in nature,are divided into first-order phase transitions(FOPTs)and continuous ones in current classification.While the latter shows striking phenomena of scaling and universality,the former has recently also been demonstrated to exhibit scaling and universal behavior within a mesoscopic,coarse-grained Landau-Ginzburg theory.Here we apply this theory to a microscopic model-the paradigmatic Ising model,which undergoes FOPTs between two ordered phases below its critical temperature-and unambiguously demonstrate universal scaling behavior in such FOPTs.These results open the door for extending the theory to other microscopic FOPT systems and experimentally testing them to systematically uncover their scaling and universal behavior. 展开更多
关键词 first order phase transitions scaling universalitythe paradigmatic ising modelwhich two dimensional Ising model coarse grained Landau Ginzburg theory scaling universal behavior phase transitionsas universal scaling
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M2 macrophages-derived exosomes for osteonecrosis of femoral head treatment:modulating neutrophil extracellular traps formation and endothelial phenotype transition 被引量:2
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作者 Guanzhi Liu Ruomu Cao +5 位作者 Qimeng Liu Heng Li Peng Yan Kunzheng Wang Run Tian Pei Yang 《Bone Research》 2025年第4期855-865,共11页
Exosomes have shown good potential in ischemic injury disease treatments.However,evidence about their effect and molecular mechanisms in osteonecrosis of femoral head(ONFH)treatment is still limited.Here,we revealed t... Exosomes have shown good potential in ischemic injury disease treatments.However,evidence about their effect and molecular mechanisms in osteonecrosis of femoral head(ONFH)treatment is still limited.Here,we revealed the cell biology characters of ONFH osteonecrosis area bone tissue in single cell scale and thus identified a novel ONFH treatment approach based on M2 macrophages-derived exosomes(M2-Exos).We further show that M2-Exos are highly effective in the treatment of ONFH by modulating the phenotypes communication between neutrophil and endothelium including neutrophil extracellular traps formation and endothelial phenotype transition.Additionally,we identified that M2-Exos’therapeutic effect is attributed to the high content of miR-93-5p and constructed miR-93-5p overexpression model in vitro and in vivo based on lentivirus and adenoassociated virus respectively.Then we found miR-93-5p can not only reduce neutrophil extracellular traps formation but also improve angiogenic ability of endothelial cells.These results provided a new theoretical basis for the clinical application of ONFH therapeutic exosomes. 展开更多
关键词 modulating phenotypes comm cell biology characters ischemic injury disease miR p osteonecrosis femoral neutrophil extracellular traps macrophages derived exosomes endothelial phenotype transition
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Medium-entropy configuration enabling reversible P2-OP4 phase transition in layered oxides for high-rate sodium-ion batteries 被引量:2
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作者 Fei-Fei Hong Xin Zhou +9 位作者 Hao Liu Gui-Lin Feng Xiao-Hong Liu Heng Zhang Wei-Feng Fan Bin Zhang Mei-Hua Zuo Wang-Yan Xing Ping Zhang Wei Xiang 《Rare Metals》 2025年第5期2997-3007,共11页
Layered transition metal oxides have emerged as promising cathode materials for sodium ion batteries.However,irreversible phase transitions cause structural distortion and cation rearrangement,leading to sluggish Na+d... Layered transition metal oxides have emerged as promising cathode materials for sodium ion batteries.However,irreversible phase transitions cause structural distortion and cation rearrangement,leading to sluggish Na+dynamics and rapid capacity decay.In this study,we propose a medium-entropy cathode by simultaneously introducing Fe,Mg,and Li dopants into a typical P2-type Na_(0.75)Ni_(0.25)Mn_(0.75)O_(2)cathode.The modified Na_(0.75)Ni_(0.2125)Mn_(0.6375)Fe_(0.05)Mg_(0.05)Li_(0.05)O_(2)cathode predominantly exhibits a main P2 phase(93.5%)with a minor O3 phase(6.5%).Through spectroscopy techniques and electrochemical investigations,we elucidate the redox mechanisms of Ni^(2+/3+/4+),Mn^(3+/4+),Fe^(3+/4+),and O_(2)-/O_(2)^(n-)during charging/discharging.The medium-entropy doping mitigates the detrimental P2-O_(2)phase transition at high-voltage,replacing it with a moderate and reversible structural evolution(P2-OP4),thereby enhancing structural stability.Consequently,the modified cathode exhibits a remarkable rate capacity of 108.4 mAh·g^(-1)at 10C,with a capacity retention of 99.0%after 200 cycles at 1C,82.5%after 500 cycles at 5C,and 76.7%after 600 cycles at 10C.Furthermore,it also demonstrates superior electrochemical performance at high cutoff voltage of 4.5 V and extreme temperature(55 and 0℃).This work offers solutions to critical challenges in sodium ion batteries cathode materials. 展开更多
关键词 Layered oxide cathode Sodium ion batteries Phase transition Medium-entropy P2/O3 biphasic structure
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South Sudan: The Perils of Security Governance and the Treacherous Path to Democratic Transition 被引量:1
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作者 Luka Biong Deng Kuol 《International Relations and Diplomacy》 2025年第2期50-73,共24页
There is a growing recognition of the critical role of security governance in advancing democratic transition in the post-conflict environment.Despite such a recognition,the security sector reform concept has overshad... There is a growing recognition of the critical role of security governance in advancing democratic transition in the post-conflict environment.Despite such a recognition,the security sector reform concept has overshadowed the importance of the overarching strategic role of security governance in transition to democracy,particularly in Africa.This paper assesses the status and challenges facing security governance and how they thwarted the efforts to furthering the democratic transition in South Sudan.The paper shows a deterioration in security,safety and security governance outcomes since the independence of South Sudan in 2011 with such a trend unlikely to be abated in the near future without strategic interventions.Some of the challenges facing security governance in South Sudan include the legacies of some historical events including the“Big Tent Policy”,absence of strategic leadership,lack of overarching policy framework,impractical and tenuous security arrangements in the 2018 peace agreement,persistent postponement of the first elections,and dysfunctional justice sector.The paper provides some strategic and operational recommendations to improve security governance and advance democratic transition in South Sudan.These recommendations include formulation of an inclusive and people-centered national security policy,rigorous judicial reform,and early political agreement on new political infrastructure if conditions for holding the first national elections are not met in 2026. 展开更多
关键词 SECURITY GOVERNANCE South Sudan Peace Agreement POLICY JUSTICE REFORM Democratic transition
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Anlotinib reverses osimertinib resistance by inhibiting epithelial-to-mesenchymal transition and angiogenesis in nonsmall cell lung cancer 被引量:1
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作者 Liting Lyu Xin Hua +5 位作者 Jiaxin Liu Sutong Zhan Qianqian Zhang Xiao Liang Jian Feng Yong Song 《Journal of Biomedical Research》 2025年第5期452-466,共15页
In the present study,we aimed to investigate whether anlotinib reverses osimertinib resistance by inhibiting the formation of epithelial-mesenchymal transition(EMT)and angiogenesis.In a clinical case,anlotinib reverse... In the present study,we aimed to investigate whether anlotinib reverses osimertinib resistance by inhibiting the formation of epithelial-mesenchymal transition(EMT)and angiogenesis.In a clinical case,anlotinib reversed osimertinib resistance in non-small cell lung cancer(NSCLC).Therefore,we performed immunohistochemical analyses on tumor tissues from three NSCLC patients with osimertinib resistance to analyze alterations in the expression levels of EMT markers and vascular endothelial growth factor A(VEGFA)before and after the development of osimertinib resistance.The results revealed the downregulation of E-cadherin,coupled with the upregulation of vimentin and VEGFA in tumor tissues of patients exhibiting osimertinib resistance,compared with those in tissues from patients before receiving osimertinib.Subsequently,we established osimertinib-resistant(Osi-R)cell lines and found that the Osi-R cells acquired EMT features.Next,we analyzed the synergistic effects of the combination therapy to verify whether anlotinib could reverse osimertinib resistance by inhibiting EMT.The expression levels of VEGFA and tube formation were analyzed in the combination group in vitro.Finally,we determined the reversal of osimertinib resistance by the combination of osimertinib and anlotinib in vivo using 20 nude mice.The combined treatment of osimertinib and anlotinib effectively prevented the metastasis of Osi-R cells,inhibited tumor growth,exerted antitumor activity,and ultimately reversed osimertinib resistance in mice.The co-administration of osimertinib and anlotinib demonstrated synergistic efficacy in inhibiting EMT and angiogenesis in three NSCLC patients,ultimately reversing osimertinib resistance. 展开更多
关键词 non-small cell lung cancer osimertinib anlotinib RESISTANCE epithelial-to-mesenchymal transition
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Tectonic transition from the Paleo-Asian Ocean to the Paleo- Pacific Ocean: insights from volcano-sedimentary rocks in NE China 被引量:1
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作者 MENG Weihao WANG Hongyan ZHOU Jianbo 《Global Geology》 2025年第1期11-34,共24页
Since the Paleozoic,the tectonic evolution of northeastern Eurasia has been primarily influenced by the Paleo-Asian Ocean and the Paleo-Pacific tectonic domains.However,the spatial and temporal frameworks,as well as t... Since the Paleozoic,the tectonic evolution of northeastern Eurasia has been primarily influenced by the Paleo-Asian Ocean and the Paleo-Pacific tectonic domains.However,the spatial and temporal frameworks,as well as the timing of the tectonic transition between these two oceanic domains,remain unclear.For addressing these issues,we present petrological,geochronological,and geochemical data for andesite and sandstone samples from the Seluohe Group along the Jilin-Yanji Suture between the Jiamusi-Khanka Block and the North China Craton.The geochemical results indicate that the andesite sample is high-Mg andesite.Its magma source was generated by the metasomatized mantle wedge influenced by fluids derived from the subducted slab in a continental island arc setting.The high-Mg andesite gives the crystallization ages of Early Triassic(249±3 Ma).The sandstone is immature greywacke with a maximum depositional age of Early Triassic(247±1 Ma),and its sediments primarily originate from concurrent magmatic rocks within a juvenile continental arc.Based on our new findings,we propose that the Seluohe Group represents an Early Triassic volcanic-sedimentary association with continental island arc characteristics associated with the southwestward subduction of the Heilongjiang Ocean.We identified a sedimentary basin intimately associated with one or more continental arcs along the northeastern edge of the North China Craton.We suggest that the southwestward subduction of the Jilin-Heilongjiang Ocean in the Early Mesozoic accounts for this continental arc setting.There is a distinct temporal gap between the closure of the Paleo-Asian Ocean(ca.260 Ma)and the onset of Paleo-Pacific plate subduction(234–220 Ma),which is essentially coeval with the southwestward subduction of the Jilin-Heilongjiang Ocean between 255 Ma and 239 Ma. 展开更多
关键词 High-Mg andesite sedimentary basin Early Mesozoic Jilin-Heilongjiang Ocean tectonic transition in northeastern Eurasia
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Energy Transition and Sustainable Development:Global Energy Market Analysis and Outlook for 2025 被引量:1
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作者 Zhou Jie 《China Oil & Gas》 2025年第1期I0001-I0004,共4页
China Oil&Gas,as a prominent academic journal in the energy industry,has been dedicated to advancing academic research and industrial development in the oil and gas energy field.As one of the authoritative media o... China Oil&Gas,as a prominent academic journal in the energy industry,has been dedicated to advancing academic research and industrial development in the oil and gas energy field.As one of the authoritative media outlets in the international energy sector,the magazine has long focused on the evolution of the global energy landscape and has organized and participated in several influential academic activities and research projects. 展开更多
关键词 SUSTAINABLE OUTLOOK transition
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