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Research on the Rehabilitation Treatment Effect of Sensory Integration Training Combined with Cognitive Training in Children with Mental Retardation
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作者 Chunhui Song Ying Tian 《Journal of Clinical and Nursing Research》 2026年第1期123-130,共8页
Objective:To analyze the clinical effect of sensory integration training combined with cognitive training in the rehabilitation treatment of children with mental retardation.Methods:A total of 120 children with mental... Objective:To analyze the clinical effect of sensory integration training combined with cognitive training in the rehabilitation treatment of children with mental retardation.Methods:A total of 120 children with mental retardation who received rehabilitation intervention in our hospital from January 2022 to December 2025 were selected and divided into a control group and an experimental group,with 60 children in each group.The control group adopted a conventional rehabilitation training program;the experimental group adopted a combined sensory integration training and cognitive training program.The sensory integration ability,cognitive function,and daily living skills of children in the two groups were compared.Results:The sensory integration ability score of the experimental group(85.3±6.2)was significantly higher than that of the control group(72.1±7.5)(p<0.05);the cognitive function score(88.7±5.8)was significantly improved compared with that of the control group(76.4±6.9)(p<0.05);the daily living skills score(90.2±4.7)was significantly higher than that of the control group(80.5±5.3)(p<0.05).The social interaction ability of the experimental group reached 92.5%,which was significantly higher than that of the control group(81.3%)(p<0.05).Conclusion:Sensory integration training combined with cognitive training demonstrates favorable outcomes in the rehabilitation treatment of children with mental retardation,exhibiting a notable neurofunctional remodeling effect.It can optimize the multidimensional rehabilitation process,effectively enhance the comprehensive developmental potential of children,and hold significant clinical application value. 展开更多
关键词 Sensory integration training Cognitive training Mental retardation
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Meetings and Courses
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作者 Shui-Ying Lei 《Hepatobiliary & Pancreatic Diseases International》 2026年第1期I0009-I0010,共2页
Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication.This list is provided as a service to readers;inclusion does not imply endorsement by ... Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication.This list is provided as a service to readers;inclusion does not imply endorsement by the Hepatobiliary&Pancreatic Diseases International. 展开更多
关键词 courses MONTHS service PUBLICATION FORMAT meetings SUBMISSION ANNOUNCEMENTS
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Influence of diet-induced obesity and voluntary exercise training on cardiac lipids and mitochondrial function in mice
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作者 Nimna Perera Minh Deo +11 位作者 Surafel Tegegne Yow Keat Tham Natalie A.Mellett Anida Velagic Alex M.Parker Oliver K.Fuller Lauren V.Terry Casey L.Egan Peter J.Meikle Rebecca H.Ritchie Mark A.Febbraio Miles J.De Blasio 《Journal of Sport and Health Science》 2026年第1期56-71,共16页
Background Obesity is a risk factor for developing cardiometabolic disease.Exercise training is pivotal in the treatment of obesity and is associated with reduced cardiovascular mortality.This study examined the effec... Background Obesity is a risk factor for developing cardiometabolic disease.Exercise training is pivotal in the treatment of obesity and is associated with reduced cardiovascular mortality.This study examined the effect of high-fat feeding on cardiac morphology and mitochondrial function,alongside the mitigating effects of voluntary exercise training.Methods Six-week-old male C57Bl/6 J mice commenced a high fat diet(HFD)or chow diet and were randomized to receive locked(sedentary)or unlocked(voluntary exercise training(VET))running wheels at 10 weeks of age.Mice were monitored until 30 weeks of age and euthanized for collection of tissues.Magnetic resonance imaging was performed to assess body composition,and echocardiography was performed to assess cardiac function.Results Compared with chow-fed animals,the HFD increased body weight and adiposity and decreased cardiolipins(CL)in the heart,which are required for maintaining adequate mitochondrial respiration.Importantly,VET reversed these effects and induced physiological cardiac hypertrophy.Cardiac mitochondrial respiratory chain analysis revealed decreased complexes II and IV activity following high fat feeding,while VET enhanced complex I activity,emphasizing the cardioprotective effect of exercise training in obesity.Conclusion This study uncovers mechanisms by which obesity and exercise impact cardiac mitochondrial health and suggests the mitochondria is a therapeutic target in obesity-related cardiovascular diseases. 展开更多
关键词 Cardiovascular disease MITOCHONDRIA OBESITY CARDIOLIPIN Exercise training
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Discussion on Application of AI Image Generation in Undergraduate Landscape Architecture Courses
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作者 Yu MENG 《Asian Agricultural Research》 2026年第2期35-36,41,共3页
With the rapid development of image-generative AI (artificial intelligence) technology, its application in undergraduate Landscape Architecture education has demonstrated significant potential. Based on this, the pres... With the rapid development of image-generative AI (artificial intelligence) technology, its application in undergraduate Landscape Architecture education has demonstrated significant potential. Based on this, the present study explores the implications of integrating image-generative AI into Landscape Architecture courses from three perspectives: stimulating students creative design potential, expanding approaches to form and concept generation, and enhancing the visualization of spatial scenes. Furthermore, it discusses application strategies from three dimensions: AI-assisted conceptual generation, human-machine collaboration for design refinement, and optimization of scheme presentation and evaluation. This paper aims to provide relevant educators with insights and references. 展开更多
关键词 AI image generation Landscape Architecture courses Application strategy
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Does longer-muscle length resistance training cause greater longitudinal growth in humans?A systematic review
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作者 Milo Wolf Patroklos Androulakis Korakakis +6 位作者 Michael D.Roberts Daniel L.Plotkin Martino V.Franchi Bret Contreras Menno Henselmans Stian Larsen Brad J.Schoenfeld 《Sports Medicine and Health Science》 2026年第1期34-42,共9页
Background:This paper aimed to systematically review the literature regarding the effects of resistance training(RT)performed at longer-muscle length(LML)versus shorter-muscle length(SML)on proxy measurements for long... Background:This paper aimed to systematically review the literature regarding the effects of resistance training(RT)performed at longer-muscle length(LML)versus shorter-muscle length(SML)on proxy measurements for longitudinal hypertrophy.Methods:We included studies that satisfied the following criteria:(1)be a resistance training intervention with a comparison of LML vs SML-RT;(2)assess both fascicle length(FL)and muscle size pre-and post-intervention;(3)involve healthy adults aged≥18 years;(4)be published in an English-language journal,and;(5)have a minimum training intervention duration of 4 weeks.Three databases were searched in February 2024(Google Scholar,PubMed/Medline,Scopus)for relevant articles,alongside'forward'and'backward'citation searching of articles included and additions via authors'personal knowledge.The results of studies were described narratively,compared,and contrasted.Eight studies met the inclusion criteria,totaling a sample size of 120.Results:Our results suggest that both muscle size and fascicle length increases may be greater following LML-RT versus SML-RT,suggesting LML-RT may lead to greater longitudinal hypertrophy than SML-RT.Notably,evidence is largely mixed;no studies to date have attempted to estimate serial sarcomere number changes from LML versus SML-RT,and all but one study used linear extrapolation methods to estimate FL,which has questionable validity.Therefore,the structural adaptations underlying hypertrophy from LML-RT remain undetermined.Conclusion:In conclusion,results suggest that LML-RT may be superior to SML-RT for inducing muscle hypertrophy and,more specifically,longitudinal growth,though evidence is mixed. 展开更多
关键词 sarcomerogenesis Lengthened partials Range of motion Strength training
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Efficacy of vaginal androgen combined with pelvic floor muscle training for stress urinary incontinence in postmenopausal women:a randomized-controlled trial
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作者 Yingxiu Chen Zhongyu Ren +1 位作者 Jiasheng Yan Yang Yu 《The Canadian Journal of Urology》 2026年第1期143-154,共12页
Objectives:Postmenopausal women with stress urinary incontinence(SUI)exhibit low androgen expression.This study aimed to evaluate the efficacy and safety of vaginal androgen combined with pelvic floor muscle training(... Objectives:Postmenopausal women with stress urinary incontinence(SUI)exhibit low androgen expression.This study aimed to evaluate the efficacy and safety of vaginal androgen combined with pelvic floor muscle training(PFMT)in the treatment of SUI in postmenopausal women.Methods:Postmenopausal women with SUI were recruited from Hainan West Central Hospital between January 2024 and March 2025.Participants were randomly assigned in a double-blind manner to receive either vaginal androgen cream combined with PFMT(treatment group)or a visually identical placebo cream(without androgens)combined with PFMT(control group).The vaginal cream was applied to the vaginal wall at a dose of 0.5 g per application,twice weekly for a total of 10 applications,while PFMT was conducted for 8 weeks.The clinical efficacy and safety were compared between the two groups.Results:A total of 61 patients were finally enrolled,with 31 in the treatment group and 30 in the control group.At both 3-month and 6-month follow-ups,the treatment group demonstrated significantly lower values in daily pad usage(p<0.05),24-h pad test scores(p<0.05),and ICIQ-UI SF scores(p<0.05)compared to the control group.The improvement rate of urinary incontinence was significantly higher in the treatment group(p<0.05).Compared to baseline,the treatment group showed statistically significant reductions in all three outcome measures(all p<0.05).No severe adverse events were reported in either group during the treatment period.Conclusions:Androgen therapy combined with PFMT significantly improved the urinary incontinence remission rate in postmenopausal women with SUI,with no severe adverse effects observed.These findings suggest that androgen therapy may represent a novel therapeutic approach for SUI management in postmenopausal women. 展开更多
关键词 ANDROGEN pelvic floor muscle training MENOPAUSE stress urinary incontinence WOMEN
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Clinical Investigation into the Functional Rehabilitation of Patients with Chronic Low Back Pain Utilizing Core Stability Training Combined with Conventional Rehabilitation
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作者 Fei LI Jinlun WU 《Medicinal Plant》 2026年第1期40-42,45,共4页
[Objectives]To investigate the clinical efficacy of core stability training combined with conventional rehabilitation in the functional recovery of patients suffering from chronic low back pain.[Methods]A randomized c... [Objectives]To investigate the clinical efficacy of core stability training combined with conventional rehabilitation in the functional recovery of patients suffering from chronic low back pain.[Methods]A randomized controlled trial design was employed in this study.Ninety patients with chronic low back pain were recruited and randomly assigned to either a control group(n=45),which received conventional rehabilitation,or an experimental group(n=45),which received conventional rehabilitation combined with core stability training.Both groups underwent treatment for 6 weeks.Assessments were conducted using the visual analogue scale(VAS),Oswestry disability index(ODI),and finger-to-floor test prior to treatment,6 weeks following treatment,and during the follow-up period,respectively.[Results]Prior to treatment,no statistically significant differences were observed between the two patient groups in terms of general information and various baseline measurements(P>0.05).Following 6 weeks of treatment and throughout the follow-up period,both groups demonstrated significant improvements in VAS scores,ODI scores,and lumbar anteflexion range of motion compared to baseline measurements(P<0.05).Notably,the magnitude of improvement in the experimental group exceeded that of the control group,with this inter-group difference reaching statistical significance(P<0.05).No serious adverse reactions were reported during the treatment process.[Conclusions]Core stability training combined with conventional rehabilitation can significantly enhance the alleviation of pain and functional impairments in patients suffering from chronic low back pain.This approach holds valuable implications for the optimization of rehabilitation treatment protocols. 展开更多
关键词 Chronic low back pain Core stability training Functional impairment PAIN
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Bridging the gap:A scoping review of wet and dry lab simulation training in orthopaedic surgical education
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作者 Sari Wathiq Al Hajaj Chandramohan Ravichandran +4 位作者 Karthic Swaminathan Sanjeevi Bharadwaj Vishnu V Nair Hussein Shoukry Sriram Srinivasan 《World Journal of Orthopedics》 2026年第1期132-139,共8页
BACKGROUND Orthopaedic surgical education has traditionally depended on the apprenticeship model of“see one,do one,teach one”.However,reduced operative exposure,stricter work-hour regulations,medicolegal constraints... BACKGROUND Orthopaedic surgical education has traditionally depended on the apprenticeship model of“see one,do one,teach one”.However,reduced operative exposure,stricter work-hour regulations,medicolegal constraints,and patient safety concerns have constrained its practicality.Simulation-based training has become a reliable,safe,and cost-efficient alternative.Dry lab techniques,especially virtual and augmented reality,make up 78%of current dry lab research,whereas wet labs still set the standard for anatomical realism.AIM To evaluate the effectiveness,limitations,and future directions of wet and dry lab simulation in orthopaedic training.METHODS A scoping review was carried out across four databases-PubMed,Cochrane Library,Web of Science,and EBSCOhost-up to 2025.Medical Subject Headings included:"Orthopaedic Education","Wet Lab","Dry Lab","Simulation Training","Virtual Reality",and"Surgical Procedure".Eligible studies focused on orthopaedic or spinal surgical education,employed wet or dry lab techniques,and assessed training effectiveness.Exclusion criteria consisted of non-English publications,abstracts only,non-orthopaedic research,and studies unrelated to simulation.Two reviewers independently screened titles,abstracts,and full texts,resolving discrepancies with a third reviewer.RESULTS From 1851 records,101 studies met inclusion:78 on dry labs,7 on wet labs,4 on both.Virtual reality(VR)simulations were most common,with AI increasingly used for feedback and assessment.Cadaveric training remains the gold standard for accuracy and tactile feedback,while dry labs-especially VR-offer scalability,lower cost(40%-60%savings in five studies),and accessibility for novices.Senior residents prefer wet labs for complex tasks;juniors favour dry labs for basics.Challenges include limited transferability data,lack of standard outcome metrics,and ethical concerns about cadaver use and AI assessment.CONCLUSION Wet and dry labs each have unique strengths in orthopaedic training.A hybrid approach combining both,supported by standardised assessments and outcome studies,is most effective.Future efforts should aim for uniform reporting,integrating new technologies,and policy support for hybrid curricula to enhance skills and patient care. 展开更多
关键词 Orthopaedic education Wet lab Dry lab Simulation training Virtual reality Surgical procedure
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Advances in the application of virtual reality technology in ophthalmic surgical skills training
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作者 Jia-Wen Wei Qing Zhang +4 位作者 Xiao-Yan Wang Ming-Xue Huang Jin-Hua Gan Wei-Hua Yang Wei Chi 《International Journal of Ophthalmology(English edition)》 2026年第2期393-404,共12页
Conventional surgical teaching techniques face several challenges,highlighting a necessity for ongoing innovation in ophthalmology education to align with the evolving demands of clinical practice.The recent rapid adv... Conventional surgical teaching techniques face several challenges,highlighting a necessity for ongoing innovation in ophthalmology education to align with the evolving demands of clinical practice.The recent rapid advancement of computer technology has enabled the integration of virtual reality(VR)into medical training,thereby revolutionizing ophthalmic surgical education through VRbased educational methods.VR technology offers a safe,risk-free environment for trainees to practice repeatedly,enhancing surgical skills and accelerating the learning curve without compromising patient safety.This research outlines the application of VR technology in ophthalmic surgical skills training,particularly in cataract and vitreoretinal surgery.Including assessing the effectiveness of intraocular surgery training systems,evaluating skills transfer to the operating room,comparing it with wet lab cataract surgery training,and enhancing non-dominant hand training for cataract surgery,among other aspects.Additionally,this paper will identify the limitations of VR technology in ocular surgical skills training,offer improvement strategies,and detail the advantages and prospects,with the objective of guiding subsequent researchers. 展开更多
关键词 virtual reality OPHTHALMOLOGY ophthalmic surgical skills training surgical simulation cataract surgery vitreoretinal surgery
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Clinical Investigation of Shoulder Joint Function and Pain Alleviation in Patients with Rotator Cuff Injuries via Structured Phased Rehabilitation Training
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作者 Yujie CHEN Chunming MA 《Medicinal Plant》 2026年第1期54-56,60,共4页
[Objectives]To investigate the clinical effects of implementing structured phased rehabilitation training,in addition to conventional rehabilitation,on shoulder joint function and pain alleviation in patients with rot... [Objectives]To investigate the clinical effects of implementing structured phased rehabilitation training,in addition to conventional rehabilitation,on shoulder joint function and pain alleviation in patients with rotator cuff injuries managed conservatively.[Methods]Eighty patients diagnosed with rotator cuff injury were selected and randomly assigned to either the control group or the experimental group,each comprising 40 individuals.The control group received conventional rehabilitation treatment,whereas the experimental group underwent phased rehabilitation training in addition to the conventional treatment for 6 weeks.Assessments were conducted prior to treatment,6 weeks following treatment,and 8 weeks after the completion of treatment(follow-up period).The visual analogue scale(VAS)was employed to evaluate pain intensity,the Constant-Murley score was utilized to assess shoulder joint function,and the shoulder joint range of motion was measured.[Results]Prior to treatment,no statistically significant differences were observed between the two patient groups across all measured indicators(P>0.05).Following 6 weeks of treatment and throughout the follow-up period,both groups exhibited significant reductions in VAS scores compared to baseline measurements,alongside improvements in Constant-Murley scores and shoulder joint range of motion(P<0.05).Furthermore,the magnitude of improvement in the experimental group was significantly greater than that in the control group(P<0.05).[Conclusions]Phased rehabilitation training can enhance shoulder joint function and alleviate pain in patients with rotator cuff injuries beyond the effects of conventional rehabilitation treatment,demonstrating notable clinical application value. 展开更多
关键词 Rotator cuff injury Phased rehabilitation training Shoulder joint function PAIN Randomized controlled trial
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The Impact of Early Postoperative Rehabilitation Training on Balance Ability and Quality of Life in Elderly Patients with Hip Fracture
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作者 Kaiyu Yang Xiaofang Peng Li Xu 《Journal of Clinical and Nursing Research》 2026年第1期394-399,共6页
Objective:To analyze the improvement effect of early postoperative rehabilitation training on balance ability and quality of life in elderly patients with hip fracture.Methods:A total of 50 elderly patients with hip f... Objective:To analyze the improvement effect of early postoperative rehabilitation training on balance ability and quality of life in elderly patients with hip fracture.Methods:A total of 50 elderly patients with hip fracture admitted to our hospital from January 2023 to January 2024 were selected and divided into the observation group(25 cases)and the control group(25 cases)by random number table method.The control group received routine nursing,while the observation group received early rehabilitation training on the basis of routine nursing.The balance ability(Berg Balance Scale,BBS)and quality of life(SF-36)of the two groups were compared.Results:The BBS scores of the observation group at all postoperative time points were significantly higher than those of the control group(p<0.05),and the quality-of-life scores of the observation group were also significantly higher than those of the control group(p<0.05).Conclusion:Early postoperative rehabilitation training for elderly patients with hip fracture can improve their balance ability,enhance their quality of life,and reduce the incidence of postoperative complications,which is worthy of clinical promotion. 展开更多
关键词 Elderly hip fracture Early postoperative rehabilitation training Balance ability Quality of life COMPLICATIONS
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Intermittent Hypoxia-Hyperoxia Training Ameliorates Symptoms and Improves Cerebral Perfusion Status in Patients with Cerebral Venous Outflow Disorders:A Pilot Study
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作者 Milan Jia Chenxia Zhou +8 位作者 Hui Li Jing Lan Wenbo Zhao Lingyun Jia Sijie Li Changhong Ren Chen Zhou Lu Liu Xunming Ji 《Biomedical and Environmental Sciences》 2026年第2期192-201,共10页
Objective Cerebral venous outflow disorders(CVOD)can impair cerebral perfusion and produce diverse,often debilitating symptoms,substantially reducing quality of life.Intermittent hypoxiahyperoxia training(IHHT)has dem... Objective Cerebral venous outflow disorders(CVOD)can impair cerebral perfusion and produce diverse,often debilitating symptoms,substantially reducing quality of life.Intermittent hypoxiahyperoxia training(IHHT)has demonstrated therapeutic potential across various pathologies and may represent a promising non-pharmacological approach for CVOD management.Methods Patients with imaging-confirmed CVOD underwent 14 IHHT sessions,each comprising four cycles of 10-minute hypoxia(11%O_(2))stimulation and 20-minute hyperoxia(38%O_(2)).Physiological parameters and adverse events were monitored throughout the intervention.Clinical scales,24-hour ambulatory blood pressure,blood tests,jugular ultrasound,and perfusion imaging were assessed preand post-intervention.Results No participants experienced intolerable discomfort or severe adverse events;vital signs remained within normal ranges.No significant changes were observed in 24-hour blood pressure,blood cell counts,lipid profiles,or other blood markers.Notably,60%of patients(n=12)reported overall symptom improvement on the Patient Global Impression of Change scale.Headache severity,as measured by the visual analogue scale,significantly decreased(6.33±1.22 vs.4.89±2.03,P=0.016).In patients with internal jugular vein(IJV)stenosis,significant improvements were observed in regional cerebral blood flow(including the insula,occipital lobe,internal capsule,and lenticula)and left J3-segment IJV flow volume(107.27[47.50,160.00]vs.140.83[55.00,210.00]mL/min,P=0.011).Conclusion The current IHHT protocol is safe and well-tolerated in patients with CVOD.IHHT may alleviate CVOD-related symptoms by improving oxygen saturation,cerebral perfusion,and venous outflow pattern,supporting its potential as a non-invasive therapeutic strategy. 展开更多
关键词 Cerebral vascular disease Intermittent hypoxia-hyperoxia training Cerebral venous outflow disorders Cerebral perfusion Acclimatization
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Effects of acupuncture-moxibustion combined with rehabilitation training on limb function and surface electromyography in patients with hemiplegia after stroke
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作者 XING Yingru ZHENG Yu SHANG Miaowei 《Journal of Acupuncture and Tuina Science》 2026年第1期39-47,共9页
Objective:To observe the effects of acupuncture-moxibustion combined with rehabilitation training on limb function and surface electromyography(sEMG)in patients with hemiplegia after stroke(HAS).Methods:Eighty-four HA... Objective:To observe the effects of acupuncture-moxibustion combined with rehabilitation training on limb function and surface electromyography(sEMG)in patients with hemiplegia after stroke(HAS).Methods:Eighty-four HAS patients were divided into a control group and a combined group using the random number table method,with 42 cases in each group.The control group received dynamic-static balance rehabilitation training,and the combined group additionally received Fu Zheng Bu Tu(strengthening the healthy Qi and invigorating the spleen)acupuncture-moxibustion therapy.After 4 weeks of treatment,their clinical efficacy was compared,and they were also observed for changes in limb motor function,muscle spasticity level,balance ability,sEMG indices,and hemorheological parameters,as well as adverse reactions.Results:After treatment,the combined group had a higher total effective rate than the control group(P<0.05).After the intervention,both groups presented significant increases in the upper-and lower-limb Fugl-Meyer assessment(FMA)score,Berg balance scale(BBS)score,maximum voluntary contraction(MVC),root mean square(RMS),and integrated electromyography(iEMG);the combined group had superior improvements compared to the control group(P<0.05).After treatment,the modified Ashworth scale(MAS)scores of the elbow,wrist,knee,and ankle joints,and the levels of plasma viscosity(PV),whole blood viscosity(WBV),and hematocrit(HCT)dropped in both groups and were lower in the combined group than in the control group(P<0.05).Neither group showed significant adverse reactions during the treatment period.Conclusion:Fu Zheng Bu Tu acupuncture-moxibustion plus dynamic-static balance rehabilitation training can effectively alleviate muscle spasticity,improve balance ability,enhance sEMG signal levels,modulate hemodynamics,and promote the recovery of limb motor function in HAS patients. 展开更多
关键词 Acupuncture-moxibustion Therapy Thunder-fire Moxibustion Rehabilitation training Poststroke Syndrome HEMIPLEGIA HEMODYNAMICS Surface Electromyography Randomized Controlled Trial
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Exercise training-induced extracellular miR-136-3p modulates glucose uptake and myogenesis through targeting of NRDC in human skeletal muscle
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作者 Mutsumi Katayama Elena Caria +8 位作者 Dimitri Van Simaeys Anna Yagüe Sanz Romain Barrès Kenneth Caidahl Oscar P.B.Wiklander Samir El Andaloussi Per-Olof Berggren Juleen R.Zierath Anna Krook 《Journal of Sport and Health Science》 2026年第1期40-55,共16页
Background Regular physical training induces adaptive effects across multiple organ systems,highlighting the existence of inter-organ communication networks.However,the molecular mechanisms underlying both exercise-in... Background Regular physical training induces adaptive effects across multiple organ systems,highlighting the existence of inter-organ communication networks.However,the molecular mechanisms underlying both exercise-induced adaptations and organ-to-organ signaling are not fully characterized.Circulating extracellular vesicles(EVs),including exosomes,carry molecules like microRNAs(miRNAs)that may mediate tissue crosstalk.This study aimed to identify specific exercise training-responsive miRNAs that affect skeletal muscle function.Methods miRNA expression profiles of serum-derived EVs were analyzed in healthy young individuals before and after 3 weeks endurance exercise training.Exercise training-responsive miRNAs were then validated for a functional role in cellular metabolic processes in human myotubes.Results We identified several exercise training-responsive miRNAs within exosome-rich EVs in serum,including miR-136-3p.In human myotubes,miR-136-3p enhanced glucose uptake and targeted the nardilysin convertase(NRDC)gene.Transfection of miR-136-3p or silencing of NRDC induced a shift towards glycolytic metabolism in mitochondria and modulated gene expressions related to myogenesis.Pancreatic islets were identified as a potential source of miR-136-3p based on in silico analysis of gene expression and a molecular analysis of conditioned media from isolated pancreatic islets.Conclusion MiR-136-3p is an endurance training-responsive molecular transducer that modulates glucose metabolism and cellular proliferation in myocytes.Associated with EVs,extracellular miR-136-3p may serve as a molecular messenger to communicate islet–skeletal muscle crosstalk after exercise.Extracellular miR-136-3p may serve as a molecular messenger to communicate islet–skeletal muscle crosstalk.Our results highlight a miRNA-mediated mechanism that participates in inter-organ communication to fine tune the metabolic adaptations to exercise. 展开更多
关键词 Extracellular miRNA Endurance training Human skeletal muscle miR-136-3p Nardilycin convertase(NRDC)
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Rotarod training reverses corticosterone-induced motor deficits via oligodendrocyte lineage cell modulation
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作者 Jada Chia-Di Lee Benson Wui-Man Lau +6 位作者 Suk-Yu Yau Joseph Wai-Hin Leung Harmony Kai-Hei Wong Dalinda Isabel Sanchez Vidana Tatia M.C.Lee Wu-Tian Wu Kwok-Fai So 《Neural Regeneration Research》 2026年第6期2440-2447,共8页
Adult-born oligodendrocytes are continuously produced in the brains of rodents.The functional role of these cells has been linked to the motor-related activities of healthy animals and is vital for acquiring new motor... Adult-born oligodendrocytes are continuously produced in the brains of rodents.The functional role of these cells has been linked to the motor-related activities of healthy animals and is vital for acquiring new motor skills.However,the relationship between these cells and the control of motor-related activities has not been investigated in pathological conditions.Therefore,the aim of this study is to investigate the role of oligodendrocytes in depression-related motor deficits and the effects of training.Psychomotor retardation is a key symptom of depression.Consistent with the impairments observed in rodent motor performance,the proliferation and activation of adult-born oligodendrocytes are altered in a corticosterone-induced stress paradigm.Therapeutic rotarod training can alleviate these symptoms by reversing the aforementioned changes.Notably,these alterations are particularly pronounced in layer I of the motor cortex.Thus,this study provides evidence of the potential functional involvement of adult-born oligodendrocytes in the motor impairments observed in the depressed animals.Additionally,it offers preliminary results for further investigation into layer I of the motor cortex in relation to these pathological conditions. 展开更多
关键词 corticosterone-induced stress EXERCISE major depressive disorder motor cortex motor deficits motor training MYELINATION oligodendrocyte lineage cells oligodendrocyte precursor cells psychomotor retardation
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Research on Innovation of Blended Teaching Mode in Comprehensive Practical Training Course of Financial Accounting in Colleges and Universities
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作者 Yunfeng Wang 《Journal of Contemporary Educational Research》 2025年第9期182-188,共7页
Against the backdrop of the digital era,profound changes have taken place in the education industry.The development of information technology has affected the teaching of financial accounting majors in colleges and un... Against the backdrop of the digital era,profound changes have taken place in the education industry.The development of information technology has affected the teaching of financial accounting majors in colleges and universities.The traditional teaching mode can hardly meet the needs of talent cultivation.Therefore,in the comprehensive practical training course of financial accounting,it is necessary to attach importance to the implementation of blended teaching,effectively innovate the teaching mode,and improve the effectiveness of talent cultivation.From the perspective of the comprehensive practical training course of financial accounting in colleges and universities,this paper analyzes the application value of blended teaching and puts forward specific teaching practice strategies,aiming to enhance the educational effect of the course and provide reference for the subsequent reform of professional courses. 展开更多
关键词 Colleges and universities Comprehensive practical training course of financial accounting Blended teaching
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CDIO Based Optimization of Urban Planning Personnel Training Courses in Forestry Universities 被引量:6
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作者 Ming SUN Jun ZHANG +1 位作者 Jun DONG Bing CHANG 《Asian Agricultural Research》 2014年第9期81-84,共4页
On the basis of analyzing existing course system of urban planning discipline,this paper came up with a framework for optimization of urban planning personnel training mode and course system,oriented towards training ... On the basis of analyzing existing course system of urban planning discipline,this paper came up with a framework for optimization of urban planning personnel training mode and course system,oriented towards training practical engineering personnel and based on CDIO engineering education and teaching platform. Then it made empirical study on setting of the urban planning discipline in Northeast Forestry University. It proposed changing the original "3 + 2" course system,exploring and optimizing the course system,improving teaching effect of urban planning personnel training courses,and raising planning and design ability of students. 展开更多
关键词 training mode of URBAN planning PERSONNEL CDIO ENG
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The Reform Scheme of Practice-Courses Cooperation Training Pattern of Software Engineering Major of Overseas Chinese Universities 被引量:2
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作者 Jin Gou Wei Luo +1 位作者 Kongjie Lin Yaxuan Zhang 《计算机教育》 2018年第12期147-154,共8页
How to improve the employment of software engineering graduates, especially, how to effectively enhance the employment competitiveness of relevant overseas students in the context of "One Belt and One Road" ... How to improve the employment of software engineering graduates, especially, how to effectively enhance the employment competitiveness of relevant overseas students in the context of "One Belt and One Road" is one of the core tasks of overseas Chinese universities. This paper proposes a reform plan for the practical training mode of school-enterprise cooperative project in the software engineering of overseas Chinese universities. The reform plan combines education concepts with practical research and development. It subdivides students and according to the characteristics of different types of students, and is carried out on campus, outside campus(in the province), and abroad(original area), which makes senior undergraduates fully understand the needs of enterprises, constantly improve their professional practice ability, and improve their competitiveness. Thus, the professional innovation and entrepreneurship ability of students is enhanced, and it also reduces the cost of employee entry. 展开更多
关键词 SOFTWARE engineering OVERSEAS students project training
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Transurethral resection of bladder tumor: A systematic review of simulator-based training courses and curricula 被引量:2
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作者 Panagiotis Kallidonis Angelis Peteinaris +6 位作者 Gernot Ortner Kostantinos Pagonis Costantinos Adamou Athanasios Vagionis Evangelos Liatsikos Bhaskar Somani Theodoros Tokas 《Asian Journal of Urology》 CSCD 2024年第1期1-9,共9页
Objective:Transurethral resection of bladder tumor is one of the most common everyday urological procedures.This kind of surgery demands a set of skills that need training and experience.In this review,we aimed to inv... Objective:Transurethral resection of bladder tumor is one of the most common everyday urological procedures.This kind of surgery demands a set of skills that need training and experience.In this review,we aimed to investigate the current literature to find out if simulators,phantoms,and other training models could be used as a tool for teaching urologists.Methods:A systematic review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses statement and the recommendations of the European Association of Urology guidelines for conducting systematic reviews.Fifteen out of 932 studies met our inclusion criteria and are presented in the current review.Results:The UroTrainer(Karl Storz GmbH,Tuttlingen,Germany),a virtual reality training simulator,achieved positive feedback and an excellent face and construct validity by the participants.The inspection of bladder mucosa,blood loss,tumor resection,and procedural time was improved after the training,especially for inexperienced urologists and medical students.The construct validity of UroSim®(VirtaMed,Zurich,Switzerland)was established.SIMBLA simulator(Samed GmbH,Dresden,Germany)was found to be a realistic and useful tool by experts and urologists with intermediate experience.The test objective competency model based on SIMBLA simulator could be used for evaluating urologists.The porcine model of the Asian Urological Surgery Training and Education Group also received positive feedback by the participants that tried it.The Simulation and Technology Enhanced Learning Initiative Project had an extraordinary face and content validity,and 60%of participants would like to use the simulators in the future.The 5-day multimodal training curriculum“Boot Camp”in the United Kingdom achieved an increase of the level of confidence of the participants that lasted months after the project.Conclusion:Simulators and courses or curricula based on a simulator training could be a valuable learning tool for any surgeon,and there is no doubt that they should be a part of every urologist's technical education. 展开更多
关键词 SIMULATOR train CURRICULUM Transurethral resection VAPORESECTION Laser BLADDER
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Design and Development of Small Modular Courses for“Education-Training Integration”in Vocational Colleges:A Case Study 被引量:1
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作者 Zhixin Feng Meiqin Liang 《Journal of Contemporary Educational Research》 2024年第4期10-15,共6页
Vocational education plays a vital role in the development of skilled technical professionals and the advancement of the economy.However,the emphasis on campus education often neglects the importance of external train... Vocational education plays a vital role in the development of skilled technical professionals and the advancement of the economy.However,the emphasis on campus education often neglects the importance of external training,hindering the overall development of vocational education.This study aims to address this issue by exploring the design and development of small modular courses that integrate training and education in vocational colleges,focusing on the mechanics course as a case study.The research methods employed in this study include an in-depth analysis of enterprise training needs,the development of digital teaching resources utilizing the finite element method(FEM),and the implementation of a small modular course integrating education and training.The data analysis reveals positive outcomes in terms of learners’comprehension and engagement with complex mechanics formulas through the use of stress nephograms and other digital resources.This research provides a new perspective on curriculum design and offers insights into the integration of training and education in vocational colleges.The findings underscore the significance of incorporating innovative teaching methodologies and digital resources in enhancing the quality and relevance of vocational education,ultimately contributing to the cultivation of skilled professionals and the growth of the vocational education sector. 展开更多
关键词 Education-training integration Small modular courses Vocational colleges training Finite element method
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