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Cryopreservation of bovine sperm causes single‑strand DNA breaks that are localized in the toroidal regions of chromatin
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作者 Jordi Ribas‑Maynou Rodrigo Muiño +1 位作者 Carolina Tamargo Marc Yeste 《Journal of Animal Science and Biotechnology》 2025年第1期92-106,共15页
Background Sperm cryopreservation is widely used in the cattle industry,as it allows for disassociating the localiza-tion of sires and the collection of semen from the timing of artificial insemination.While freeze-th... Background Sperm cryopreservation is widely used in the cattle industry,as it allows for disassociating the localiza-tion of sires and the collection of semen from the timing of artificial insemination.While freeze-thawing is known to impair sperm DNA integrity,whether the damage induced consists of single-(SSB)or double-strand breaks(DSB)has not been determined.In addition,no previous study has addressed if DNA breaks preferentially reside in specific genome regions such as those forming the toroid linker regions,or are rather spread throughout the regions linked to protamines.The main aim of the present work,therefore,was to elucidate the type and localization of the DNA damage generated by cryopreservation and to evaluate its impact on artificial insemination outcomes in cattle.Results The incidence of SSB and DSB was evaluated in 12 ejaculates before and after cryopreservation with the Comet assay,and the localization of the DNA breaks was assessed using pulsed-field gel electrophoresis(PFGE).Before cryopreservation,the incidence of SSB was 10.99%±4.62%and involved 20.56%±3.04%of sperm cells,whereas these figures significantly(P<0.0001)increased up to 34.11%±3.48%and 53.36%±11.00%in frozen-thawed sperm.In contrast,no significant differences in the incidence of DSB were observed(P>0.990)before and after cryopreservation(before:incidence of 13.91%±1.75%of sperm DNA affecting 56.04%±12.49%of sperm cells;after:incidence of 13.55%±1.55%of sperm DNA involving 53.36%±11.00%of sperm cells).Moreover,PFGE revealed that the percentage of sperm DNA fragments whose length was shorter than a toroid(<31.5 kb)was greater(P<0.0001)after(27.00%±4.26%)than before freeze-thawing(15.57%±4.53%).These differences indicated that the DNA breaks induced by cryopreservation affect the regions condensed in protamines,which are structured in toroids.On the other hand,in vivo fertility rates were associated to the incidence of SSB and DSB in frozen-thawed sperm(P=0.032 and P=0.005),but not with the size of the DNA fragments resulting from these breaks(P>0.05).Conclusion Cryopreservation of bovine sperm generates single-strand DNA breaks,which are mainly located in protamine-condensed toroidal regions.The incidence of DNA breaks in cryopreserved sperm has an impact on cat-tle fertility,regardless of the size of generated fragments. 展开更多
关键词 Cattle DNA damage Fertility SPERM toroid linker regions
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Toroidal torques due to n=1 magnetic perturbations in ITER baseline scenario
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作者 Jingwei LI Li LI +5 位作者 Yueqiang LIU Yunfeng LIANG Yanfei WANG Lu TIAN Zhongqing LIU Fangchuan ZHONG 《Plasma Science and Technology》 2025年第1期39-51,共13页
Toroidal torques,generated by the resonant magnetic perturbation(RMP)and acting on the plasma column,are numerically systematically investigated for an ITER baseline scenario.The neoclassical toroidal viscosity(NTV),i... Toroidal torques,generated by the resonant magnetic perturbation(RMP)and acting on the plasma column,are numerically systematically investigated for an ITER baseline scenario.The neoclassical toroidal viscosity(NTV),in particular the resonant portion,is found to provide the dominant contribution to the total toroidal torque under the slow plasma flow regime in ITER.While the electromagnetic torque always opposes the plasma flow,the toroidal torque associated with the Reynolds stress enhances the plasma flow independent of the flow direction.A peculiar double-peak structure for the net NTV torque is robustly computed for ITER,as the toroidal rotation frequency is scanned near the zero value.This structure is found to be ultimately due to a non-monotonic behavior of the wave-particle resonance integral(over the particle pitch angle)in the superbanana plateau NTV regime in ITER.These findings are qualitatively insensitive to variations of a range of factors including the wall resistivity,the plasma pedestal flow and the assumed frequency of the rotating RMP field. 展开更多
关键词 toroidal torques resonant magnetic perturbation fieds plasma flow ITER baseline scenario
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Ground state of Rydberg-dressed Bose gas confined in a toroidal trap
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作者 Lin-Xue Wang Hong-Li Yang +3 位作者 Hui Liu Si-Lin Chen Ya-Jun Wang Xiao-Fei Zhang 《Communications in Theoretical Physics》 SCIE CAS CSCD 2024年第1期29-35,共7页
The experimental realization of Rydberg dressing technology in ultracold atomic systems provides another superior platform for studying novel states of matter and macroscopic quantum phenomena.In this work,based on th... The experimental realization of Rydberg dressing technology in ultracold atomic systems provides another superior platform for studying novel states of matter and macroscopic quantum phenomena.In this work,based on the mean-field theory,we have investigated the ground-state phases of a two-component Bose–Einstein condensate with Rydberg interaction and confined in a toroidal trap.The effects of the Rydberg interaction and external potential,especially the Rydberg blockade radius,on the ground-state structure of such a system have been investigated in full parameter space.Our results show that the Rydberg blockade radius,which can be regarded as another controllable parameter,can be used to obtain a variety of ground-state phases.More interestingly,it is found that for weak Rydberg interactions,the Rydberg blockade radius breaks the spontaneous rotational symmetry of the system,leading to the formation of a discrete unit cell structure.For strongly interacting cases,it can be used to realize different orders of discrete rotational symmetry breaking. 展开更多
关键词 Bose-Einstein condensate Rydberg dressing toroidal trap
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Terahertz toroidal dipole metamaterial sensors for detection of aflatoxin B1
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作者 徐建伟 欧阳收剑 +4 位作者 段守鑫 邹林儿 叶丹妮 杨思嘉 邓晓华 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期672-676,共5页
Terahertz metamaterial biosensors have attracted significant attention in the biological field due to their advantages of label-free,real-time and in situ detection.In this paper,a highly sensitive metamaterial sensor... Terahertz metamaterial biosensors have attracted significant attention in the biological field due to their advantages of label-free,real-time and in situ detection.In this paper,a highly sensitive metamaterial sensor with semi-ring mirror symmetry based on toroidal dipole resonance is designed for a new metamaterial biosensor.It is shown that a refractive index sensitivity of 337.5 GHz per refractive index unit can be achieved under an analyte of saturated thickness near a 1.33 THz transmission dip.For biosensor samples where aflatoxin B1 is dropped on the metamaterial surface in our experiment,dip amplitudes of transmission varying from 0.1904 to 0.203 and 0.2093 are observed as aflatoxin B1 concentrations are altered from 0 to 0.001μg·ml-1 and to 0.01μg·ml-1,respectively.Furthermore,when aflatoxin B1 concentrations are 0.1μg·ml-1,1μg·ml-1,10μg·ml-1 and 100μg·ml-1,dip amplitudes of 0.2179,0.226,0.2384 and 0.2527 and dip redshifts of 10.1 GHz,20.1 GHz,27.7 GHz and 37.6 GHz are respectively observed.These results illustrate high-sensitivity,label-free detection of aflatoxin B1,enriching the applications of sensors in the terahertz domain. 展开更多
关键词 TERAHERTZ METAMATERIAL toroidal dipole aflatoxin B1
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The impact of toroidal mode coupling on high-density discharges in J-TEXT
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作者 Peng DENG Wenzhe MAO +13 位作者 Zhipeng CHEN Yinan ZHOU Peng SHI Zhoujun YANG Li GAO Tao LAN Jinlin XIE Hong LI Zian WEI Adi LIU Chu ZHOU Weixing DING Wandong LIU Ge ZHUANG 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第12期1-8,共8页
Density limit has long been a widely studied issue influencing the operating range of tokamaks.The rapid growth of the m/n=2/1(where m and n are poloidal and toroidal mode numbers,respectively)tearing mode is generall... Density limit has long been a widely studied issue influencing the operating range of tokamaks.The rapid growth of the m/n=2/1(where m and n are poloidal and toroidal mode numbers,respectively)tearing mode is generally regarded as a primary precursor to the density limit disruption.In this experiment,the coupling of the m/n=1/1 mode and the m/n=2/1 mode in highdensity plasma was observed.During a sawtooth cycle,the frequencies of the two modes gradually converge until they become equal.After that,toroidal coupling occurs between the 1/1 and 2/1 modes,resulting in a mutually fixed phase relationship.With the occurrence of toroidal coupling,the 2/1 mode is stabilized.Prior to the disruption,the cessation of the 1/1 and 2/1 mode coupling,along with the rapid growth in the amplitude of the 2/1 mode,can be observed.Additionally,under the same parameters,comparing discharges with or without the 1/1 mode,it is found that the presence of the 1/1 mode leads to higher plasma density and temperature parameters. 展开更多
关键词 toroidal coupling tearing mode density limit SAWTOOTH
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Investigation on the roles of equilibrium toroidal rotation during edge-localized mode mitigated by resonant magnetic perturbations
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作者 董良康 陈少永 +3 位作者 牟茂淋 罗杨 秦晨晨 唐昌建 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第1期16-33,共18页
The effects of equilibrium toroidal rotation during edge-localized mode(ELM)mitigated by resonant magnetic perturbation(RMP)are studied with the experimental equilibria of the EAST tokamak based on the four-field mode... The effects of equilibrium toroidal rotation during edge-localized mode(ELM)mitigated by resonant magnetic perturbation(RMP)are studied with the experimental equilibria of the EAST tokamak based on the four-field model in the BOUT++code.As the two main parameters to determine the toroidal rotation profiles,the rotation shear and magnitudes were separately scanned to investigate their roles in the impact of RMPs on peeling-ballooning(P-B)modes.On one hand,the results show that strong toroidal rotation shear is favorable for the enhancement of the self-generated E×B shearing rate<ω_(E×B)>with RMPs,leading to significant ELM mitigation with RMP in the stronger toroidal rotation shear region.On the other hand,toroidal rotation magnitudes may affect ELM mitigation by changing the penetration of the RMPs,more precisely the resonant components.RMPs can lead to a reduction in the pedestal energy loss by enhancing the multimode coupling in the turbulence transport phase.The shielding effects on RMPs increase with the toroidal rotation magnitude,leading to the enhancement of the multimode coupling with RMPs to be significantly weakened.Hence,the reduction in pedestal energy loss by RMPs decreased with the rotation magnitude.In brief,the results show that toroidal rotation plays a dual role in ELM mitigation with RMP by changing the shielding effects of plasma by rotation magnitude and affecting<ω_(E×B)>by rotation shear.In the high toroidal rotation region,toroidal rotation shear is usually strong and hence plays a dominant role in the influence of RMP on P-B modes,whereas in the low rotation region,toroidal rotation shear is weak and has negligible impact on P-B modes,and the rotation magnitude plays a dominant role in the influence of RMPs on the P-B modes by changing the field penetration.Therefore,the dual role of toroidal rotation leads to stronger ELM mitigation with RMP,which may be achieved both in the low toroidal rotation region and the relatively high rotation region that has strong rotational shear. 展开更多
关键词 edge-localized mode peeling–ballooning modes resonant magnetic perturbation toroidal rotation plasma response TOKAMAK
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Effect of toroidal mode coupling on explosive dynamics of m/n=3/1 double tearing mode
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作者 Xingqiang LU Ge GAO +2 位作者 Zhiwei MA Wei GUO Xin LI 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第10期8-16,共9页
The CLT code was used to quantitatively study the impact of toroidal mode coupling on the explosive dynamics of the m/n=3/1 double tearing mode.The focus of this study was on explosive reconnection processes,in which ... The CLT code was used to quantitatively study the impact of toroidal mode coupling on the explosive dynamics of the m/n=3/1 double tearing mode.The focus of this study was on explosive reconnection processes,in which the energy bursts and the main mode no longer dominates when the separation between two rational surfaces is relatively large in the medium range.The development of higher m and n modes is facilitated by a relatively large separation between two rational surfaces,a small q_(min)(the minimum value of the safety factor),or low resistivity.The relationships between the higher m and n mode development,explosive reconnection rate,and position exchange of 3/1 islands are summarized for the first time.Separation plays a more important role than q_(min)in enhancing the development of higher m and n modes.At a relatively large separation,the good development of higher m and n modes greatly reduces the reconnection rate and suppresses the development of the main mode,resulting in the main mode not being able to develop sufficiently large to generate the position changes of 3/1 islands. 展开更多
关键词 toroidal mode coupling higher m and n modes explosive growth reconnection rate position change
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Toroidal李代数的结构与表示 被引量:1
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作者 谭绍滨 陈福林 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2011年第2期149-164,共16页
关于Toroidal李代数结构和表示理论的进行综述.介绍了Toroidal李代数的发展历史、结构理论、表示理论以及扭Toroidal李代数与高维仿射李代数的关系,扭Toroidal李代数的不可约表示等.
关键词 toroidAL李代数 结构 表示 toroidal李代数
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Toroidal李代数上的Poisson代数结构 被引量:9
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作者 靳全勤 佟洁 《数学年刊(A辑)》 CSCD 北大核心 2007年第1期57-70,共14页
非交换的Poisson代数同时具有结合代数和李代数两种代数结构,而结合代数和李代数之间满足所谓的Leibniz法则.文中确定了Toroidal李代数上所有的Poisson代数结构,推广了仿射Kac-Moody代数上相应的结论.
关键词 toroidAL李代数 POISSON代数 Leibniz法则
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F_4型Toroidal李代数的顶点表示 被引量:1
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作者 茅新晖 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2003年第3期281-286,共6页
ADE型Toroidal李代数的顶点算子表示首先由Moody,Rao和Yokonuma在1990年给出.本文基于E6型仿射李代数的图自同构及E6型Toroidal李代数的顶点算子表示,给出了F4型Toroidal李代数的一个忠实表示.
关键词 F4型toroidal李代数 顶点表示 E6型仿射李代数 图自同构 6型toroidal李代数 顶点算子表示
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广义Virasoro-Toroidal李代数不可约模 被引量:4
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作者 谭绍滨 《数学年刊(A辑)》 CSCD 北大核心 2002年第3期311-320,共10页
本文将Kac-Moody代数A1(1)的二阶表示理论[11]推广到Toroidal李代数的情形.并给出了A1型Toroidal李代数的一类不可约表示.
关键词 KAC-MOODY代数 顶点表示 toroidal代数
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阶化平移Toroidal李代数的Boson表示
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作者 连海峰 叶从峰 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2015年第2期224-228,共5页
阶化平移Toroidal李代数是Toroidal李代数的推广,它们基本上都不是根阶化的.利用Weyl代数和Clifford代数分别构造了阶化平移Toroidal李代数的一类带参数λ的Boson表示和Fermion表示,这类表示是忠实的,并且证明这类表示是酉表示的充要条... 阶化平移Toroidal李代数是Toroidal李代数的推广,它们基本上都不是根阶化的.利用Weyl代数和Clifford代数分别构造了阶化平移Toroidal李代数的一类带参数λ的Boson表示和Fermion表示,这类表示是忠实的,并且证明这类表示是酉表示的充要条件是λ=1/2. 展开更多
关键词 toroidAL李代数 Boson表示 酉表示
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关于Toroidal李代数的某些性质
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作者 高永存 孟道骥 《南开大学学报(自然科学版)》 CAS CSCD 北大核心 2001年第3期1-6,共6页
给出了 Toroidal李代数的某些性质及多重 Loop代数的有限维不可约表示的分类和实现 .
关键词 toroidAL李代数 多重Loop代数 KAC-MOODY代数 有限约不可约表示 仿射李代数 导子代数
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G_2型2-Toroidal李代数的顶点表示
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作者 陈玉成 茅新晖 《数学研究》 CSCD 2006年第4期379-387,共9页
在[4]和[5]中已经研究了sim p ly-laced型T oro idal李代数的顶点表示,[6]文据此给出了Bl型T oro idal李代数顶点表示的构造.受[6]文启发,本文给出了G2型T oro idal李代数的顶点表示的构造,这种构造方式与D(41)的D ynk in图的顶点粘合... 在[4]和[5]中已经研究了sim p ly-laced型T oro idal李代数的顶点表示,[6]文据此给出了Bl型T oro idal李代数顶点表示的构造.受[6]文启发,本文给出了G2型T oro idal李代数的顶点表示的构造,这种构造方式与D(41)的D ynk in图的顶点粘合和一个2上循环有着紧密联系. 展开更多
关键词 toroidAL李代数 顶点算子
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阶化平移Toroidal李代数L_4的导子和泛中心扩张 被引量:1
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作者 孔小丽 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2009年第3期305-309,共5页
Toroidal李代数(加适当的中心和导子)是以Laurent多项式代数为坐标环面的扩张仿射李代数.阶化平移to-roidal李代数Ln(n≥3)是B型和D型toroidal李代数的自然推广.考虑n=4时的导子和泛中心扩张,给出L4的导子,并通过一类特殊的阶化给予证明... Toroidal李代数(加适当的中心和导子)是以Laurent多项式代数为坐标环面的扩张仿射李代数.阶化平移to-roidal李代数Ln(n≥3)是B型和D型toroidal李代数的自然推广.考虑n=4时的导子和泛中心扩张,给出L4的导子,并通过一类特殊的阶化给予证明.也给出L4的所有的2-上循环,从而得到它的泛中心扩张.可以看出结论与孔和谭文章中n≠4时有很大的不同. 展开更多
关键词 阶化平移toroidal李代数 导子 泛中心扩张
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Ordered Toroid Structures of Nanoparticles in Self-attractive Semiflexible Polymer/Nanoparticle Composites
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作者 杨志勇 柴爱华 +1 位作者 李萍 杨雍福 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2016年第3期381-388,I0002,共9页
By employing dynamic Monte Carlo simulations, we investigate a coil-to-toroid transition of self-attractive semiflexible polymers and the spatial distributions of nanoparticles in self- attractive semiflexible polymer... By employing dynamic Monte Carlo simulations, we investigate a coil-to-toroid transition of self-attractive semiflexible polymers and the spatial distributions of nanoparticles in self- attractive semiflexible polymer/nanoparticle composites. The conformation of self-attractive semiflexible polymers depends on bending energy and self-attractive interactions between monomers in polymer chains. A three-stage process of toroid formation for self-attractive semiflexible chains is shown: several isolated toroids, a loose toroid structure, and a compact toroid structure. Utilizing the compact toroid conformations of self-attractive semiflexible chains, we can control effectively the spatial distributions of nanoparticles in self-attractive semiflexible polymer nanocomposites, and an unconventional toroid structure of nanoparti- cles is observed. 展开更多
关键词 Self-attractive semiflexible polymer NANOPARTICLES toroidal structure
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Toroidal李代数及其表示
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作者 陈福林 谭绍滨 +1 位作者 王清 余铌娜 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2023年第6期889-896,共8页
Toroidal李代数是仿射Kac-Moody代数的多变量推广.在本文中我们简要介绍toroidal李代数及其表示的有关进展.
关键词 toroidAL李代数 多重loop代数 可积表示 Drinfeld表现
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Numerical study of fast ion behavior in the presence of magnetic islands and toroidal field ripple in the EAST tokamak 被引量:2
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作者 张伟 胡立群 +3 位作者 孙有文 丁斯晔 张子君 刘松林 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第10期334-341,共8页
A peculiar first orbit loss type was found apart from the normal ones when we use ORBIT code to simulate fast ion orbits in the EAST tokamak. Fast ion orbits were studied in the presence of toroidal field (TF) rippl... A peculiar first orbit loss type was found apart from the normal ones when we use ORBIT code to simulate fast ion orbits in the EAST tokamak. Fast ion orbits were studied in the presence of toroidal field (TF) ripple and magnetohydro- dynamic (MHD) perturbations. We analyzed the properties of the drifted orbits in detail and compared their differences, finding that the combined effects of ripple and magnetic islands are much greater than the effects of either one of them alone. Then we investigated the orbitdeviations as a function of pitch angle in different radial positions. The modeling results demonstrate that the loss of trapped particles is mainly caused by the ripple, while MHD'perturbation mainly plays an important role in the passing particles. Furthermore we modeled the loss rate using different equilibriums. Results prove that a higher beta can indeed improve the confinement of fast ions, while a little change in the q profile can make the topologies of magnetic islands become quite different and results in quite different total particle losses. 展开更多
关键词 fast ion toroidal field ripple magnetic island orbit drift
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Nonlinear simulation of multiple toroidal Alfvén eigenmodes in tokamak plasmas 被引量:2
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作者 Xiao-Long Zhu Feng Wang Zheng-Xiong Wang 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第2期346-355,共10页
Nonlinear evolution of multiple toroidal Alfven eigenmodes(TAEs) driven by fast ions is self-consistently investigated by kinetic simulations in toroidal plasmas.To clearly identify the effect of nonlinear coupling on... Nonlinear evolution of multiple toroidal Alfven eigenmodes(TAEs) driven by fast ions is self-consistently investigated by kinetic simulations in toroidal plasmas.To clearly identify the effect of nonlinear coupling on the beam ion loss,simulations over single-n modes are also carried out and compared with those over multiple-n modes,and the wave-particle resonance and particle trajectory of lost ions in phase space are analyzed in detail.It is found that in the multiple-n case,the resonance overlap occurs so that the fast ion loss level is rather higher than the sum loss level that represents the summation of loss over all single-n modes in the single-n case.Moreover,increasing fast ion beta β_h can not only significantly increase the loss level in the multiple-n case but also significantly increase the loss level increment between the single-n and multiple-n cases.For example,the loss level in the multiple-n case for β_h=6.0% can even reach 13% of the beam ions and is 44% higher than the sum loss level calculated from all individual single-n modes in the single-n case.On the other hand,when the closely spaced resonance overlap occurs in the multiple-n case,the release of mode energy is increased so that the widely spaced resonances can also take place.In addition,phase space characterization is obtained in both single-n and multiple-n cases. 展开更多
关键词 TOKAMAK toroidal Alfve′n eigenmode wave-particle interaction beam ion loss
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Toroidal网络C(d1,d2)的(d,4)—控制数
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作者 邵汝军 吕长虹 《南京大学学报(数学半年刊)》 CAS 2000年第1期21-26,共6页
本文讨论二维Toroidal网格的(d,4)-控制数,得到如下结果:(1)如果m≥2,G=C(2m+1)或G=C(2m+2,3),当d=diam(G)+1时,Rd,k(G)=2;(2)如果G=C(d1,4)(d1≥3... 本文讨论二维Toroidal网格的(d,4)-控制数,得到如下结果:(1)如果m≥2,G=C(2m+1)或G=C(2m+2,3),当d=diam(G)+1时,Rd,k(G)=2;(2)如果G=C(d1,4)(d1≥3)或G=C(d15)(d1≥9),当d=diam(G)时,Rd,k(G)=2。 展开更多
关键词 直径 控制数 toroidal网格
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