Large-scale mountains like Asian topographies and the Rocky Mountains have important influences on subtropical jet streams(STJs)over downstream regions in winter.The dynamical role of the Rocky Mountains in modulating...Large-scale mountains like Asian topographies and the Rocky Mountains have important influences on subtropical jet streams(STJs)over downstream regions in winter.The dynamical role of the Rocky Mountains in modulating STJs with and without the existence of East Asian(EA)topographies in northern winter is investigated via numerical experiments.In agreement with previous studies,the Rocky Mountains(topographic forcing),with the existence of EA topographies,can only strengthen the STJ from the east coast of North America to the western Atlantic region.The independent role of the Rocky Mountains,however,strengthens the STJ over not only the east coast of North America but also over Pacific regions.It is found that the existence of EA topographies can dramatically strengthen the EA trough,as well as a downstream ridge which,in the upstream of the Rocky Mountains,acts to partly cancel out the strengthening of the anticyclone to the north of the Rocky Mountains and the northward warm air transport in the high latitudes of Pacific regions due to the Rocky Mountains’forcing alone.Such circulation changes effectively weaken the Rocky Mountains–forced strengthening of the meridional temperature gradient in the midlatitude North Pacific,and thus the STJ there.Therefore,EA topographies are of great importance in modulating the role of the Rocky Mountains as a dynamical forcing of STJ variability.展开更多
The topography of gear meshing interfaces is one of the key factors affecting the dynamic characteristics of the gear transmission system.In order to obtain the contact characteristics of meshing gear pair with differ...The topography of gear meshing interfaces is one of the key factors affecting the dynamic characteristics of the gear transmission system.In order to obtain the contact characteristics of meshing gear pair with different surface micro-topographies,an interface feature model and a tribo-dynamics coupling model for the gear system are proposed in this paper.The effects of the gear tooth surface micro-topography on the oil film distribution,contact damping and friction are considered.The time-varying meshing stiffness and the static transmission error are included in the abovementioned models.An exemplary gear pair is analyzed using the proposed models to investigate the influence of the surface micro-topography on the dynamic characteristics of gear system under different micro-topographies and input torque conditions.Simulation results show that the effects of gear tooth micro-topography on the gear dynamic responses(including the friction and the vicious damping at the gear meshing interface and the vibration in the direction of offline of action)are highly dependent on the regularity of tooth surface.The vibration and noise can be significantly controlled by manufacturing a regular gear tooth profiles instead of random profiles.展开更多
Modifying substrates through mineralization is a popular way to improve the osteogenic performance.Screening of the best mineralization characteristics on specific substrates for stem cells is meaningful but not fully...Modifying substrates through mineralization is a popular way to improve the osteogenic performance.Screening of the best mineralization characteristics on specific substrates for stem cells is meaningful but not fully studied.In this paper,poly(lactic-co-glycolic acid)/hydroxyapatite(PLGA[HA,PH)microsphere scaffolds with superficial pores were fabricated by a low-temperature fusion method.After the mineralization in the 5x stimulated body fluid(SBF)for 0,7,12 and 24 h,four mineralized scaffolds(MPH-0,MPH-7,MPH-12 and MPH-24)with different apatite topographies were obtained.It was found that the surface of MPH-7 was evenly decorated with abundant micro-pores,MPH-12 with dense and plain apatite layer,and MPH-24 with small spherical bumps.The responses of mouse bone mesenchymal stem cells(mBMSCs)to the four scaffolds were further studied.The results showed that MPH-7 and MPH-24 had more obvious effects on mBMSCs attachment,proliferation and differentiation than MPH-0 and MPH-12.This work indicated that to obtain the maximum improvement,the mineralization characteristics had to be carefully chosen.This was noteworthy in the chemical modification of surfaces to form the functionalized scaffolds for bone repair.展开更多
In this paper, (-amylase organized monolayer was assembled on the surface of the PET-CO2- substrate in different conditions. The different topography of the (-amylase/PET monolayer was obtained by AFM in tapping mode.
New information and communication technologies have led to the emergence of new techniques in our daily lives. Indeed, in topography, a lightning development of new techniques and new devices has been noticed. This de...New information and communication technologies have led to the emergence of new techniques in our daily lives. Indeed, in topography, a lightning development of new techniques and new devices has been noticed. This development has given rise to a multitude of choices of devices and various classes of precision. This implies that the decision-makers have to study the adequate equipment and the appropriate technique according to the topographic task to be realized. The objective is not to compare GNSS and topographic techniques, but to point out the contribution of the Global Navigation Satelite System (GNSS) techniques of topographic work. Thus, a theoretical study with a critical eye on the scientific principle of calculating the third topographic dimension followed by a leveling campaign, Real Time Kinematic (RTK) surveys will be used in order to be able to compare and interpret the result from these campaigns. The study of the difference resulting from the practical campaigns will allow us to identify the contribution of GNSS technology.展开更多
Alluvial fans possess diverse geomorphological features and have a significant impact on soil characteristics and variations in ecological stoichiometry.However,it remains unclear how alluvial fans in arid mountainous...Alluvial fans possess diverse geomorphological features and have a significant impact on soil characteristics and variations in ecological stoichiometry.However,it remains unclear how alluvial fans in arid mountainous areas influence the changes in ecological chemical stoichiometry and,consequently,indirectly affect ecosystem function.Alluvial fan,with its diverse topographical features,exerts a multifaceted influence on soil formation and characteristics.Limited information exists regarding the ecological stoichiometric characteristics of the alluvial fan in arid mountainous areas.This study investigated the soil physical-chemical characteristics,enzyme activities,soil ecological stoichiometries,and its driving factors of four types of micro-topographies(alluvial mesas,high floodplain,groove beach,and striated groove)in the foothills of eastern Helan Mountains,China.Results showed that soil physical and chemical properties in the 0–20 cm soil depth was consistently higher than those in the 20–40 cm soil depth,with no changes in pH,total nitrogen,and total potassium.C:P and N:P ratios in alluvial mesas,high floodplain,and striated groove were significantly higher than those in groove beach.Redundancy analysis showed that soil nutrients played the most significant role in the variation of soil ecological stoichiometry characteristics.Topography influenced soil stoichiometry indirectly,primarily through impacts on enzyme activity and soil nutrient elements.These findings elucidate the intricate interplay between soil ecological stoichiometric characteristics and environmental factors across diverse micro-topographies in alluvial fan,contributing to our understanding of the formation and development of soil in dryland.展开更多
Surface topographies of cell culture substrates can be used to generate in vitro cell culture environments similar to the in vivo cell niches. In vivo, the physical properties of the extracellular matrix (ECM), such a...Surface topographies of cell culture substrates can be used to generate in vitro cell culture environments similar to the in vivo cell niches. In vivo, the physical properties of the extracellular matrix (ECM), such as its topography, provide physical cues that play an important role in modulating cell function. Mimicking these properties remains a challenge to provide in vitro realistic environments for cells. Artificially generated substrates’ topographies were used extensively to explore this important surface cue. More recently, the replication of natural surface topographies has been enabling to exploration of characteristics such as hierarchy and size scales relevant for cells as advanced biomimetic substrates. These substrates offer more realistic and mimetic environments regarding the topographies found in vivo. This review will highlight the use of natural surface topographies as a template to generate substrates for in-vitro cell culture. This review starts with an analysis of the main cell functions that can be regulated by the substrate’s surface topography through cell-substrate interactions. Then, we will discuss research works wherein substrates for cell biology decorated with natural surface topographies were used and investigated regarding their influence on cellular performance. At the end of this review, we will highlight the advantages and challenges of the use of natural surface topographies as a template for the generation of advanced substrates for cell culture.展开更多
Surface topography is one of the key factors in regulating interactions between materials and cells.While topographies presented to cells in vivo are non-symmetrical and in complex shapes,current fabrication technique...Surface topography is one of the key factors in regulating interactions between materials and cells.While topographies presented to cells in vivo are non-symmetrical and in complex shapes,current fabrication techniques are limited to replicate these complex geometries.In this study,we developed a microcasting technique and successfully produced imprinted hydroxyapatite(HAp)surfaces with nature-inspired(honeycomb,pillars,and isolated islands)topographies.The in vitro biological performance of the developed non-symmetrical topographies was evaluated using adipose-derived stem cells(ADSCs).We demonstrated that ADSCs cultured on all HAp surfaces,except honeycomb patterns,presented well-defined stress fibers and expressed focal adhesion protein(paxillin)molecules.Isolated islands topographies significantly promoted osteogenic differentiation of ADSCs with increased alkaline phosphatase activity and upregulation of key osteogenic markers,compared to the other topographies and the control unmodified(flat)HAp surface.In contrast,honeycomb topographies hampered the ability of the ADSCs to proliferate and differentiate to the osteogenic lineage.This work presents a facile technique to imprint nature-derived topographies on the surface of bioceramics which opens up opportunities for the development of bioresponsive interfaces in tissue engineering and regenerative medicine.展开更多
With hard turning, which is an attractive alternative to existing grinding processes, surface quality is of great importance. Signal processing techniques were used to relate workpiece surface topography to the dynami...With hard turning, which is an attractive alternative to existing grinding processes, surface quality is of great importance. Signal processing techniques were used to relate workpiece surface topography to the dynamic behavior of the machine tool. Spatial domain frequency analyses based on fast Fourier transform were used to analyze the tool behavior. Wavelet reconstruction was used for profile filtering. The results show that machine vibration remarkably affects the surface topography at small feed rates, but has negligible effect at high feed rates. The analyses also show how to control the surface quality during hard turning.展开更多
This paper is devoted to a multi-mesh-scale approach for describing the dynamic behaviors of thin geophysical mass flows on complex topographies.Because the topographic surfaces are generally non-trivially curved,we i...This paper is devoted to a multi-mesh-scale approach for describing the dynamic behaviors of thin geophysical mass flows on complex topographies.Because the topographic surfaces are generally non-trivially curved,we introduce an appropriate local coordinate system for describing the flow behaviors in an efficient way.The complex surfaces are supposed to be composed of a finite number of triangle elements.Due to the unequal orientation of the triangular elements,the distinct flux directions add to the complexity of solving the Riemann problems at the boundaries of the triangular elements.Hence,a vertex-centered cell system is introduced for computing the evolution of the physical quantities,where the cell boundaries lie within the triangles and the conventional Riemann solvers can be applied.Consequently,there are two mesh scales:the element scale for the local topographic mapping and the vertex-centered cell scale for the evolution of the physical quantities.The final scheme is completed by employing the HLL-approach for computing the numerical flux at the interfaces.Three numerical examples and one application to a large-scale landslide are conducted to examine the performance of the proposed approach as well as to illustrate its capability in describing the shallow flows on complex topographies.展开更多
The Hengduan Mountains,situated on the southeastern edge of the Qinghai-Tibet Plateau,are the longest and widest north-south-oriented mountain range in China,exerting a significant influence on the ecological and geog...The Hengduan Mountains,situated on the southeastern edge of the Qinghai-Tibet Plateau,are the longest and widest north-south-oriented mountain range in China,exerting a significant influence on the ecological and geographical pattern.Understanding the topographic and geomorphological characteristics of the Hengduan Mountains is fundamental and crucial for research in related fields such as ecology,geography,and sustainability.In this study,Digital Elevation Model(DEM)data were utilized to extract and analyze the topography and geomorphology(TG)pattern.TG maps have been developed to quantitatively classify the TG types in the Hengduan Mountains by combining the five factors of elevation,slope,aspect,relief and landform.The spatial distribution and quantitative characteristics of these factors were mapped and investigated using geographic information systems.The results revealed that:(1)The Hengduan Mountains exhibit an elongated north-south distribution,with an average elevation of approximately 3746 m,an average slope of around 25°,and an average relief of about 266 m.(2)The Hengduan Mountains display significant elevation differences,with an overall high elevation,characterized by a trend of lower elevation in the east and higher elevation in the west,as well as irregular orientations of various aspects.(3)The 19 landform types were identified,the landform types of the Hengduan Mountains are primarily composed of low-relief high-mountains(42.0618%),low-relief mid-mountains(22.4624%),and high-elevation hills(20.5839%).The results of the study can provide data and information support for the ecology,environmental protection and sustainable development of the Hengduan Mountains.展开更多
Traumatic injuries to the central nervous system(CNS) result in disruption of the intricate network of axons which connect functionally related neurons that are widely distributed throughout the brain and spinal cord....Traumatic injuries to the central nervous system(CNS) result in disruption of the intricate network of axons which connect functionally related neurons that are widely distributed throughout the brain and spinal cord.Under normal conditions,maintenance of this complex system is structurally and functionally supported by astrocytes (ACs)and other glial cells,the processes of which form a framework surrounding neuronal cell bodies,dendrites,axons,and synapses.展开更多
Machine learning models are increasingly used to correct the vertical biases(mainly due to vegetation and buildings)in global Digital Elevation Models(DEMs),for downstream applications which need‘‘bare earth"el...Machine learning models are increasingly used to correct the vertical biases(mainly due to vegetation and buildings)in global Digital Elevation Models(DEMs),for downstream applications which need‘‘bare earth"elevations.The predictive accuracy of these models has improved significantly as more flexible model architectures are developed and new explanatory datasets produced,leading to the recent release of three model-corrected DEMs(FABDEM,DiluviumDEM and FathomDEM).However,there has been relatively little focus so far on explaining or interrogating these models,especially important in this context given their downstream impact on many other applications(including natural hazard simulations).In this study we train five separate models(by land cover environment)to correct vertical biases in the Copernicus DEM and then explain them using SHapley Additive exPlanation(SHAP)values.Comparing the models,we find significant variation in terms of the specific input variables selected and their relative importance,suggesting that an ensemble of models(specialising by land cover)is likely preferable to a general model applied everywhere.Visualising the patterns learned by the models(using SHAP dependence plots)provides further insights,building confidence in some cases(where patterns are consistent with domain knowledge and past studies)and highlighting potentially problematic variables in others(such as proxy relationships which may not apply in new application sites).Our results have implications for future DEM error prediction studies,particularly in evaluating a very wide range of potential input variables(160 candidates)drawn from topographic,multispectral,Synthetic Aperture Radar,vegetation,climate and urbanisation datasets.展开更多
Harrat Lunayyir,a volcanic field in western Saudi Arabia,exhibits diverse geomorphological and topographical features shaped by volcanic,tectonic,and climatic processes.This study integrates field observations,remote ...Harrat Lunayyir,a volcanic field in western Saudi Arabia,exhibits diverse geomorphological and topographical features shaped by volcanic,tectonic,and climatic processes.This study integrates field observations,remote sensing,and GIS analysis to investigate the spatial distribution and relationships between volcanic landforms,lava flows,and topographical variation result obtained is a morphological classification of the cinder cones of Harrat Lunayyir,which can be sub-divided into four types:tephra rings,horseshoe-shaped volcanoes,multiple volcanoes and volcanoes without craters.All of these are monogenetic volcanoes,unlike central volcanoes(stratovolcanoes)which live for tens or hundreds of thousands of years and erupt numerous times.In Harrat Lunayyir,there is a clear dominance of arched horseshoe-shaped volcanoes(58)over ring-shaped cinder cones(10),A1_symmetric cones(circular,uniform cinder cones with a single crater)(32),A2_asymmetric cones(elongated,irregular cones and may feature one or more craters)(8),volcanoes without craters(55)and multiple volcanoes(20).The classification presented in this paper makes it possible to include all morphological types of volcanoes found in the region.This fact also renders the present classification a useful tool to apply in other,both insular and continental volcanic areas to eventually analyze and systematize the study of eruptive edifices with similar traits.Hence,this research will explore the standard physical volcanology literature so as to follow accepted definitions.展开更多
Progressive modifications in submarine topography and shorelines drastically affect tidal dynamics in bays.This study examines the influence of topographic slope,bay length,and driving forces on tidal currents followi...Progressive modifications in submarine topography and shorelines drastically affect tidal dynamics in bays.This study examines the influence of topographic slope,bay length,and driving forces on tidal currents following land reclamation.Tidal equa-tions are analytically solved using infinite series,deriving expressions for tidal levels and currents in narrow bays with varying topog-raphy.Tidal levels,influenced by topographic variations,are characterized by amplitude and phase lag of their complex amplitude.These levels demonstrate high sensitivity to longitudinal slope variations but remain relatively stable under lateral slope changes.Un-der constant topographic slopes,even minor changes in bay length can drastically modify amplitude and phase lag,highlighting the sensitivity of tidal dynamics to geometric alterations.Tidal velocity notably increases with steeper longitudinal slopes and modestly rises with elevated lateral slopes.However,changes in longitudinal and lateral slopes do not considerably alter flow patterns.While external forces predominantly regulate tidal velocity with negligible effects on flow patterns,endogenous resistance influences veloci-ty but minimally impacts flow structure.These findings enhance the understanding of tidal responses to geometric and topographic changes,providing valuable guidance for land reclamation projects and coastal management strategies.展开更多
This study presents finely resolved radar signatures of multiple cyclonic vortices associated with an EF2 tornadic supercell that occurred in Guangzhou on 16 June 2022 and discusses how the mesocyclone formed on the l...This study presents finely resolved radar signatures of multiple cyclonic vortices associated with an EF2 tornadic supercell that occurred in Guangzhou on 16 June 2022 and discusses how the mesocyclone formed on the lee side of mountain.A nearby X-band phased-array radar provides evidence that the mesocyclone was shallow,with a depth generally confined to less than 3 km.The mesocyclonic feature was observed to initiate from near-ground level,driven by the interaction between intensifying cold pool surges and shallow lee-side ambient flows.It was first recognized shortly after the presence of near-ground cyclonic convergence signatures over the leading edges of cold pool outflows.Over the subsequent 17 min,the mesocyclone developed upward,reaching a maximum height of 3 km,and produced a tornado 8min later.Nearly coinciding with the time of tornadogenesis,a noticeable separation of the low-level tornado cyclone from the midlevel mesocyclone was observed.This shift in the vertically oriented vortex tube was likely caused by modifications to the low-level flow due to the complex hilly terrain or by occlusions associated with rear-flank downdrafts.After tornadogenesis,high-resolution X-PAR observations revealed that the lowest-level mesocyclonic signature contracted into a gate-to-gate tornadic vortex signature(TVS)at the tip of hook echoes.Compared to conventional S-band operational weather radars,rapid-scan X-PAR observations indicate that a core diameter threshold of 1.5–2 km could be employed to identify a cyclonically sheared radial velocity couplet as a TVS,potentially extending the lead time for Doppler-based tornado warnings.展开更多
Fog is a highly complex weather phenomenon influenced by numerous factors.This study investigated the impact of the Changbai Mountains’topography on the formation and development of spring fog in the Bohai Sea.From 1...Fog is a highly complex weather phenomenon influenced by numerous factors.This study investigated the impact of the Changbai Mountains’topography on the formation and development of spring fog in the Bohai Sea.From 12 to 14 May 2021,the Bohai region experienced a sea fog event.Utilizing Himawari-8 satellite data,ERA5 reanalysis dataset,land and sea station observations,the WRF model,a topography sensitivity experiment,and backward trajectory tracking,the influence of the Changbai Mountains’topography on the evolution of this sea fog event was assessed.Results indicated that the Changbai Mountains’topography significantly impacted the propagation and concentration of the sea fog through dual effects—namely,the Venturi Effect and Foehn Clearance Effect.Comparative simulations incorporating and excluding the Changbai Mountains revealed that its topography favored weak convergence(Venturi Effect)of low-level airflow over the Bohai Sea induced by a high-pressure system,promoting westward fog expansion.Additionally,the backward trajectory analysis further indicated that the Foehn Clearance Effect of the Changbai Mountains extended its influence far beyond the immediate lee side,contributing to significant changes in atmospheric conditions such as reductions in relative humidity and increases in potential temperature.The dry,warm foehn contributed to a reduction in the liquid water content,ultimately leading to the weakening or even dissipation of the sea fog in the region close to the Changbai Mountains.This study emphasizes the crucial role of the Changbai Mountains’topography in the development and evolution of fog,providing valuable insights for forecasting fog in regions with complex terrain.展开更多
Geomorphometric modeling and mapping of Antarctic oases are promising for obtaining new quantitative knowledge about the topography of these unique landscapes and for the further use of morphometric information in Ant...Geomorphometric modeling and mapping of Antarctic oases are promising for obtaining new quantitative knowledge about the topography of these unique landscapes and for the further use of morphometric information in Antarctic research.Within the framework of a project to create a thematic physical-geographical scientific reference geomorphometric atlas of ice-free areas of Antarctica,we performed geomorphometric modeling and mapping of the Bunger Hills(Knox Coast,Wilkes Land,East Antarctica),one of the largest Antarctic oases.By processing a fragment of the Reference Elevation Model of Antarctica(REMA)covering the Bunger Hills and adjacent glaciers,we created,for the first time,a series of 37 medium-to large-scale maps of nine of the most scientifically important morphometric variables(i.e.,slope gradient,slope aspect,vertical curvature,horizontal curvature,maximal curvature,minimal curvature,catchment area,topographic wetness index,and stream power index).The morphometric maps describe the topography of the Bunger Hills in a quantitative,rigorous,and reproducible manner.New morphometric data can be useful for further geological,geomorphological,glaciological,ecological,and hydrological studies of this Antarctic oasis.展开更多
Objective:To evaluate the performance of orthokeratology(ortho-k)lens reordering using software-designed system,so as to determine the feasibility of ortho-k lens reordering without discontinuing lens wear.Methods:Thi...Objective:To evaluate the performance of orthokeratology(ortho-k)lens reordering using software-designed system,so as to determine the feasibility of ortho-k lens reordering without discontinuing lens wear.Methods:This study is a retrospective analysis of data of ortho-k lens wearers who had a history of short-term discontinuation of lens wear.A total of 94 individuals aged over 8 years with spherical equivalent refraction ranging from-0.50 to-6.50 diopters were included.The corneal topography data at baseline(before ortho-k)and after lens wear discontinuation(cessation of ortho-k treatment)were imported separately into the lens-design software,along with corresponding refraction data.Subsequently,corneal and lens parameters were generated and compared.Intraclass correlation coefficients(ICC)were calculated,and Bland and Altman analyses were conducted.Results:All 94 children were involved in the retrospective analysis.Compared with baseline data,there was a high level of consistency between Rwo(without discontinuation)and Rwith(with discontinuation),with an ICC of 0.96(P<0.001).Furthermore,the comparison of lens parameters generated by the Easyfit software between baseline and after short-term discontinuation showed a high degree of consistency,with all of the ICC values exceeding 0.90.Similar results were obtained using the WAVE software,as both ICC values and Bland-Altman plots demonstrated a high level of consistency in lens parameters between two conditions(nearly all data points fell within the 95%LoAs).Conclusions:It is feasible to directly reorder new ortho-k lenses using software fitting approaches.However,further investigations are necessary to validate their practicability in a clinical setting.展开更多
基金supported by the Strategic Priority Research Program of Chinese Academy of Sciences [grant number XDA17010105-02]Key Research Program of Frontier Sciences,CAS [grant number QYZDY-SSW-DQC018]the National Natural Science Foundation of China [grant numbers91437105,41430533,and 41575041]
文摘Large-scale mountains like Asian topographies and the Rocky Mountains have important influences on subtropical jet streams(STJs)over downstream regions in winter.The dynamical role of the Rocky Mountains in modulating STJs with and without the existence of East Asian(EA)topographies in northern winter is investigated via numerical experiments.In agreement with previous studies,the Rocky Mountains(topographic forcing),with the existence of EA topographies,can only strengthen the STJ from the east coast of North America to the western Atlantic region.The independent role of the Rocky Mountains,however,strengthens the STJ over not only the east coast of North America but also over Pacific regions.It is found that the existence of EA topographies can dramatically strengthen the EA trough,as well as a downstream ridge which,in the upstream of the Rocky Mountains,acts to partly cancel out the strengthening of the anticyclone to the north of the Rocky Mountains and the northward warm air transport in the high latitudes of Pacific regions due to the Rocky Mountains’forcing alone.Such circulation changes effectively weaken the Rocky Mountains–forced strengthening of the meridional temperature gradient in the midlatitude North Pacific,and thus the STJ there.Therefore,EA topographies are of great importance in modulating the role of the Rocky Mountains as a dynamical forcing of STJ variability.
基金Projects(51905053,51805051)supported by the National Natural Science Foundation of ChinaProject(cstc2019jcyj-bshX0119)supported by the Chongqing Postdoctoral Science Foundation,China。
文摘The topography of gear meshing interfaces is one of the key factors affecting the dynamic characteristics of the gear transmission system.In order to obtain the contact characteristics of meshing gear pair with different surface micro-topographies,an interface feature model and a tribo-dynamics coupling model for the gear system are proposed in this paper.The effects of the gear tooth surface micro-topography on the oil film distribution,contact damping and friction are considered.The time-varying meshing stiffness and the static transmission error are included in the abovementioned models.An exemplary gear pair is analyzed using the proposed models to investigate the influence of the surface micro-topography on the dynamic characteristics of gear system under different micro-topographies and input torque conditions.Simulation results show that the effects of gear tooth micro-topography on the gear dynamic responses(including the friction and the vicious damping at the gear meshing interface and the vibration in the direction of offline of action)are highly dependent on the regularity of tooth surface.The vibration and noise can be significantly controlled by manufacturing a regular gear tooth profiles instead of random profiles.
基金supported by the National Basic Research Program of China(No.2012CB619100)the National Natural Science Foundation of China(No.51372085)+2 种基金Guangdong-Hongkong Common Technology Bidding Project(No.2013B010136003)the Shenzhen Science and Technology Program(No.JCYJ20150401145529010)Fundamental Research Funds for the Central Universities(2013ZZ0005)
文摘Modifying substrates through mineralization is a popular way to improve the osteogenic performance.Screening of the best mineralization characteristics on specific substrates for stem cells is meaningful but not fully studied.In this paper,poly(lactic-co-glycolic acid)/hydroxyapatite(PLGA[HA,PH)microsphere scaffolds with superficial pores were fabricated by a low-temperature fusion method.After the mineralization in the 5x stimulated body fluid(SBF)for 0,7,12 and 24 h,four mineralized scaffolds(MPH-0,MPH-7,MPH-12 and MPH-24)with different apatite topographies were obtained.It was found that the surface of MPH-7 was evenly decorated with abundant micro-pores,MPH-12 with dense and plain apatite layer,and MPH-24 with small spherical bumps.The responses of mouse bone mesenchymal stem cells(mBMSCs)to the four scaffolds were further studied.The results showed that MPH-7 and MPH-24 had more obvious effects on mBMSCs attachment,proliferation and differentiation than MPH-0 and MPH-12.This work indicated that to obtain the maximum improvement,the mineralization characteristics had to be carefully chosen.This was noteworthy in the chemical modification of surfaces to form the functionalized scaffolds for bone repair.
文摘In this paper, (-amylase organized monolayer was assembled on the surface of the PET-CO2- substrate in different conditions. The different topography of the (-amylase/PET monolayer was obtained by AFM in tapping mode.
文摘New information and communication technologies have led to the emergence of new techniques in our daily lives. Indeed, in topography, a lightning development of new techniques and new devices has been noticed. This development has given rise to a multitude of choices of devices and various classes of precision. This implies that the decision-makers have to study the adequate equipment and the appropriate technique according to the topographic task to be realized. The objective is not to compare GNSS and topographic techniques, but to point out the contribution of the Global Navigation Satelite System (GNSS) techniques of topographic work. Thus, a theoretical study with a critical eye on the scientific principle of calculating the third topographic dimension followed by a leveling campaign, Real Time Kinematic (RTK) surveys will be used in order to be able to compare and interpret the result from these campaigns. The study of the difference resulting from the practical campaigns will allow us to identify the contribution of GNSS technology.
基金funded by the Key Project of Natural Science Foundation of the Ningxia Hui Autonomous Region(2022AAC02020)the Chinese Academy of Engineering and Local Cooperation(2021NXZD8)the Yinchuan Natural Resources Bureau Research Project(022204129004).
文摘Alluvial fans possess diverse geomorphological features and have a significant impact on soil characteristics and variations in ecological stoichiometry.However,it remains unclear how alluvial fans in arid mountainous areas influence the changes in ecological chemical stoichiometry and,consequently,indirectly affect ecosystem function.Alluvial fan,with its diverse topographical features,exerts a multifaceted influence on soil formation and characteristics.Limited information exists regarding the ecological stoichiometric characteristics of the alluvial fan in arid mountainous areas.This study investigated the soil physical-chemical characteristics,enzyme activities,soil ecological stoichiometries,and its driving factors of four types of micro-topographies(alluvial mesas,high floodplain,groove beach,and striated groove)in the foothills of eastern Helan Mountains,China.Results showed that soil physical and chemical properties in the 0–20 cm soil depth was consistently higher than those in the 20–40 cm soil depth,with no changes in pH,total nitrogen,and total potassium.C:P and N:P ratios in alluvial mesas,high floodplain,and striated groove were significantly higher than those in groove beach.Redundancy analysis showed that soil nutrients played the most significant role in the variation of soil ecological stoichiometry characteristics.Topography influenced soil stoichiometry indirectly,primarily through impacts on enzyme activity and soil nutrient elements.These findings elucidate the intricate interplay between soil ecological stoichiometric characteristics and environmental factors across diverse micro-topographies in alluvial fan,contributing to our understanding of the formation and development of soil in dryland.
基金This work is a result of the project FROnTHERA(NORTE-01-0145-FEDER-000023)supported by Norte Portugal Regional Operational Programme(NORTE 2020)+3 种基金under the PORTUGAL 2020 Partnership Agreement,through the European Regional Development Fund(ERDF)Portuguese Foundation for Science and Technology under the doctoral programme in Tissue Engineering,Regenerative Medicine and Stem Cells(PD/59/2013)(PD/BD/128087/2016)by the project Cells4_IDs(PTDC/BTM-SAL/28882/2017).
文摘Surface topographies of cell culture substrates can be used to generate in vitro cell culture environments similar to the in vivo cell niches. In vivo, the physical properties of the extracellular matrix (ECM), such as its topography, provide physical cues that play an important role in modulating cell function. Mimicking these properties remains a challenge to provide in vitro realistic environments for cells. Artificially generated substrates’ topographies were used extensively to explore this important surface cue. More recently, the replication of natural surface topographies has been enabling to exploration of characteristics such as hierarchy and size scales relevant for cells as advanced biomimetic substrates. These substrates offer more realistic and mimetic environments regarding the topographies found in vivo. This review will highlight the use of natural surface topographies as a template to generate substrates for in-vitro cell culture. This review starts with an analysis of the main cell functions that can be regulated by the substrate’s surface topography through cell-substrate interactions. Then, we will discuss research works wherein substrates for cell biology decorated with natural surface topographies were used and investigated regarding their influence on cellular performance. At the end of this review, we will highlight the advantages and challenges of the use of natural surface topographies as a template for the generation of advanced substrates for cell culture.
文摘Surface topography is one of the key factors in regulating interactions between materials and cells.While topographies presented to cells in vivo are non-symmetrical and in complex shapes,current fabrication techniques are limited to replicate these complex geometries.In this study,we developed a microcasting technique and successfully produced imprinted hydroxyapatite(HAp)surfaces with nature-inspired(honeycomb,pillars,and isolated islands)topographies.The in vitro biological performance of the developed non-symmetrical topographies was evaluated using adipose-derived stem cells(ADSCs).We demonstrated that ADSCs cultured on all HAp surfaces,except honeycomb patterns,presented well-defined stress fibers and expressed focal adhesion protein(paxillin)molecules.Isolated islands topographies significantly promoted osteogenic differentiation of ADSCs with increased alkaline phosphatase activity and upregulation of key osteogenic markers,compared to the other topographies and the control unmodified(flat)HAp surface.In contrast,honeycomb topographies hampered the ability of the ADSCs to proliferate and differentiate to the osteogenic lineage.This work presents a facile technique to imprint nature-derived topographies on the surface of bioceramics which opens up opportunities for the development of bioresponsive interfaces in tissue engineering and regenerative medicine.
基金Supported by the DAAD (German Academic Exchange Service)
文摘With hard turning, which is an attractive alternative to existing grinding processes, surface quality is of great importance. Signal processing techniques were used to relate workpiece surface topography to the dynamic behavior of the machine tool. Spatial domain frequency analyses based on fast Fourier transform were used to analyze the tool behavior. Wavelet reconstruction was used for profile filtering. The results show that machine vibration remarkably affects the surface topography at small feed rates, but has negligible effect at high feed rates. The analyses also show how to control the surface quality during hard turning.
文摘This paper is devoted to a multi-mesh-scale approach for describing the dynamic behaviors of thin geophysical mass flows on complex topographies.Because the topographic surfaces are generally non-trivially curved,we introduce an appropriate local coordinate system for describing the flow behaviors in an efficient way.The complex surfaces are supposed to be composed of a finite number of triangle elements.Due to the unequal orientation of the triangular elements,the distinct flux directions add to the complexity of solving the Riemann problems at the boundaries of the triangular elements.Hence,a vertex-centered cell system is introduced for computing the evolution of the physical quantities,where the cell boundaries lie within the triangles and the conventional Riemann solvers can be applied.Consequently,there are two mesh scales:the element scale for the local topographic mapping and the vertex-centered cell scale for the evolution of the physical quantities.The final scheme is completed by employing the HLL-approach for computing the numerical flux at the interfaces.Three numerical examples and one application to a large-scale landslide are conducted to examine the performance of the proposed approach as well as to illustrate its capability in describing the shallow flows on complex topographies.
基金funded by the Yunnan Provincial Basic Research Joint Special Fund Project(2019FH001(-052))Cangshan Mountain Synthetic Scientific Expeditions Fund.
文摘The Hengduan Mountains,situated on the southeastern edge of the Qinghai-Tibet Plateau,are the longest and widest north-south-oriented mountain range in China,exerting a significant influence on the ecological and geographical pattern.Understanding the topographic and geomorphological characteristics of the Hengduan Mountains is fundamental and crucial for research in related fields such as ecology,geography,and sustainability.In this study,Digital Elevation Model(DEM)data were utilized to extract and analyze the topography and geomorphology(TG)pattern.TG maps have been developed to quantitatively classify the TG types in the Hengduan Mountains by combining the five factors of elevation,slope,aspect,relief and landform.The spatial distribution and quantitative characteristics of these factors were mapped and investigated using geographic information systems.The results revealed that:(1)The Hengduan Mountains exhibit an elongated north-south distribution,with an average elevation of approximately 3746 m,an average slope of around 25°,and an average relief of about 266 m.(2)The Hengduan Mountains display significant elevation differences,with an overall high elevation,characterized by a trend of lower elevation in the east and higher elevation in the west,as well as irregular orientations of various aspects.(3)The 19 landform types were identified,the landform types of the Hengduan Mountains are primarily composed of low-relief high-mountains(42.0618%),low-relief mid-mountains(22.4624%),and high-elevation hills(20.5839%).The results of the study can provide data and information support for the ecology,environmental protection and sustainable development of the Hengduan Mountains.
文摘Traumatic injuries to the central nervous system(CNS) result in disruption of the intricate network of axons which connect functionally related neurons that are widely distributed throughout the brain and spinal cord.Under normal conditions,maintenance of this complex system is structurally and functionally supported by astrocytes (ACs)and other glial cells,the processes of which form a framework surrounding neuronal cell bodies,dendrites,axons,and synapses.
文摘Machine learning models are increasingly used to correct the vertical biases(mainly due to vegetation and buildings)in global Digital Elevation Models(DEMs),for downstream applications which need‘‘bare earth"elevations.The predictive accuracy of these models has improved significantly as more flexible model architectures are developed and new explanatory datasets produced,leading to the recent release of three model-corrected DEMs(FABDEM,DiluviumDEM and FathomDEM).However,there has been relatively little focus so far on explaining or interrogating these models,especially important in this context given their downstream impact on many other applications(including natural hazard simulations).In this study we train five separate models(by land cover environment)to correct vertical biases in the Copernicus DEM and then explain them using SHapley Additive exPlanation(SHAP)values.Comparing the models,we find significant variation in terms of the specific input variables selected and their relative importance,suggesting that an ensemble of models(specialising by land cover)is likely preferable to a general model applied everywhere.Visualising the patterns learned by the models(using SHAP dependence plots)provides further insights,building confidence in some cases(where patterns are consistent with domain knowledge and past studies)and highlighting potentially problematic variables in others(such as proxy relationships which may not apply in new application sites).Our results have implications for future DEM error prediction studies,particularly in evaluating a very wide range of potential input variables(160 candidates)drawn from topographic,multispectral,Synthetic Aperture Radar,vegetation,climate and urbanisation datasets.
文摘Harrat Lunayyir,a volcanic field in western Saudi Arabia,exhibits diverse geomorphological and topographical features shaped by volcanic,tectonic,and climatic processes.This study integrates field observations,remote sensing,and GIS analysis to investigate the spatial distribution and relationships between volcanic landforms,lava flows,and topographical variation result obtained is a morphological classification of the cinder cones of Harrat Lunayyir,which can be sub-divided into four types:tephra rings,horseshoe-shaped volcanoes,multiple volcanoes and volcanoes without craters.All of these are monogenetic volcanoes,unlike central volcanoes(stratovolcanoes)which live for tens or hundreds of thousands of years and erupt numerous times.In Harrat Lunayyir,there is a clear dominance of arched horseshoe-shaped volcanoes(58)over ring-shaped cinder cones(10),A1_symmetric cones(circular,uniform cinder cones with a single crater)(32),A2_asymmetric cones(elongated,irregular cones and may feature one or more craters)(8),volcanoes without craters(55)and multiple volcanoes(20).The classification presented in this paper makes it possible to include all morphological types of volcanoes found in the region.This fact also renders the present classification a useful tool to apply in other,both insular and continental volcanic areas to eventually analyze and systematize the study of eruptive edifices with similar traits.Hence,this research will explore the standard physical volcanology literature so as to follow accepted definitions.
基金supported by the National Natural Sci-ence Foundation of China(No.U2106204)the Shanxi Water Conservancy Science and Technology Re-search and Extension Project(No.2023ZF19).
文摘Progressive modifications in submarine topography and shorelines drastically affect tidal dynamics in bays.This study examines the influence of topographic slope,bay length,and driving forces on tidal currents following land reclamation.Tidal equa-tions are analytically solved using infinite series,deriving expressions for tidal levels and currents in narrow bays with varying topog-raphy.Tidal levels,influenced by topographic variations,are characterized by amplitude and phase lag of their complex amplitude.These levels demonstrate high sensitivity to longitudinal slope variations but remain relatively stable under lateral slope changes.Un-der constant topographic slopes,even minor changes in bay length can drastically modify amplitude and phase lag,highlighting the sensitivity of tidal dynamics to geometric alterations.Tidal velocity notably increases with steeper longitudinal slopes and modestly rises with elevated lateral slopes.However,changes in longitudinal and lateral slopes do not considerably alter flow patterns.While external forces predominantly regulate tidal velocity with negligible effects on flow patterns,endogenous resistance influences veloci-ty but minimally impacts flow structure.These findings enhance the understanding of tidal responses to geometric and topographic changes,providing valuable guidance for land reclamation projects and coastal management strategies.
基金supported by the National Key R&D Program of China(2022YFC3004101)the National Natural Science Foundation of China(Grant No.42275006)+2 种基金the Guangdong Basic and Applied Basic Research Foundation(Grant No.2022A1515011814)the China Meteorological Administration Tornado Key Laboratory(Grant No.TKL202302)the Science and Technology Research Project of Guangdong Meteorological Service(Grant No.GRMC2023Q35)。
文摘This study presents finely resolved radar signatures of multiple cyclonic vortices associated with an EF2 tornadic supercell that occurred in Guangzhou on 16 June 2022 and discusses how the mesocyclone formed on the lee side of mountain.A nearby X-band phased-array radar provides evidence that the mesocyclone was shallow,with a depth generally confined to less than 3 km.The mesocyclonic feature was observed to initiate from near-ground level,driven by the interaction between intensifying cold pool surges and shallow lee-side ambient flows.It was first recognized shortly after the presence of near-ground cyclonic convergence signatures over the leading edges of cold pool outflows.Over the subsequent 17 min,the mesocyclone developed upward,reaching a maximum height of 3 km,and produced a tornado 8min later.Nearly coinciding with the time of tornadogenesis,a noticeable separation of the low-level tornado cyclone from the midlevel mesocyclone was observed.This shift in the vertically oriented vortex tube was likely caused by modifications to the low-level flow due to the complex hilly terrain or by occlusions associated with rear-flank downdrafts.After tornadogenesis,high-resolution X-PAR observations revealed that the lowest-level mesocyclonic signature contracted into a gate-to-gate tornadic vortex signature(TVS)at the tip of hook echoes.Compared to conventional S-band operational weather radars,rapid-scan X-PAR observations indicate that a core diameter threshold of 1.5–2 km could be employed to identify a cyclonically sheared radial velocity couplet as a TVS,potentially extending the lead time for Doppler-based tornado warnings.
基金jointly supported by the National Natural Science Foundation of China[grant number 42205009]the Open Grants of the State Key Laboratory of Severe Weather[grant number 2024LASWB23]+1 种基金the Collaborative Innovation Project for Marine Meteorological Science and Technology in the Bohai Rim Region[grant number QYXM202315]the Research and Development Project of Hebei Provincial Meteorological Bureau[grant number 22ky26]。
文摘Fog is a highly complex weather phenomenon influenced by numerous factors.This study investigated the impact of the Changbai Mountains’topography on the formation and development of spring fog in the Bohai Sea.From 12 to 14 May 2021,the Bohai region experienced a sea fog event.Utilizing Himawari-8 satellite data,ERA5 reanalysis dataset,land and sea station observations,the WRF model,a topography sensitivity experiment,and backward trajectory tracking,the influence of the Changbai Mountains’topography on the evolution of this sea fog event was assessed.Results indicated that the Changbai Mountains’topography significantly impacted the propagation and concentration of the sea fog through dual effects—namely,the Venturi Effect and Foehn Clearance Effect.Comparative simulations incorporating and excluding the Changbai Mountains revealed that its topography favored weak convergence(Venturi Effect)of low-level airflow over the Bohai Sea induced by a high-pressure system,promoting westward fog expansion.Additionally,the backward trajectory analysis further indicated that the Foehn Clearance Effect of the Changbai Mountains extended its influence far beyond the immediate lee side,contributing to significant changes in atmospheric conditions such as reductions in relative humidity and increases in potential temperature.The dry,warm foehn contributed to a reduction in the liquid water content,ultimately leading to the weakening or even dissipation of the sea fog in the region close to the Changbai Mountains.This study emphasizes the crucial role of the Changbai Mountains’topography in the development and evolution of fog,providing valuable insights for forecasting fog in regions with complex terrain.
文摘Geomorphometric modeling and mapping of Antarctic oases are promising for obtaining new quantitative knowledge about the topography of these unique landscapes and for the further use of morphometric information in Antarctic research.Within the framework of a project to create a thematic physical-geographical scientific reference geomorphometric atlas of ice-free areas of Antarctica,we performed geomorphometric modeling and mapping of the Bunger Hills(Knox Coast,Wilkes Land,East Antarctica),one of the largest Antarctic oases.By processing a fragment of the Reference Elevation Model of Antarctica(REMA)covering the Bunger Hills and adjacent glaciers,we created,for the first time,a series of 37 medium-to large-scale maps of nine of the most scientifically important morphometric variables(i.e.,slope gradient,slope aspect,vertical curvature,horizontal curvature,maximal curvature,minimal curvature,catchment area,topographic wetness index,and stream power index).The morphometric maps describe the topography of the Bunger Hills in a quantitative,rigorous,and reproducible manner.New morphometric data can be useful for further geological,geomorphological,glaciological,ecological,and hydrological studies of this Antarctic oasis.
基金supported by the National Natural Science Foundation of China(82371089).
文摘Objective:To evaluate the performance of orthokeratology(ortho-k)lens reordering using software-designed system,so as to determine the feasibility of ortho-k lens reordering without discontinuing lens wear.Methods:This study is a retrospective analysis of data of ortho-k lens wearers who had a history of short-term discontinuation of lens wear.A total of 94 individuals aged over 8 years with spherical equivalent refraction ranging from-0.50 to-6.50 diopters were included.The corneal topography data at baseline(before ortho-k)and after lens wear discontinuation(cessation of ortho-k treatment)were imported separately into the lens-design software,along with corresponding refraction data.Subsequently,corneal and lens parameters were generated and compared.Intraclass correlation coefficients(ICC)were calculated,and Bland and Altman analyses were conducted.Results:All 94 children were involved in the retrospective analysis.Compared with baseline data,there was a high level of consistency between Rwo(without discontinuation)and Rwith(with discontinuation),with an ICC of 0.96(P<0.001).Furthermore,the comparison of lens parameters generated by the Easyfit software between baseline and after short-term discontinuation showed a high degree of consistency,with all of the ICC values exceeding 0.90.Similar results were obtained using the WAVE software,as both ICC values and Bland-Altman plots demonstrated a high level of consistency in lens parameters between two conditions(nearly all data points fell within the 95%LoAs).Conclusions:It is feasible to directly reorder new ortho-k lenses using software fitting approaches.However,further investigations are necessary to validate their practicability in a clinical setting.
