Objective:To investigate the clinical efficacy and safety of percutaneous kyphoplasty at different surgical timings in the treatment of osteoporotic vertebral compression fracture(OVCF)based on the theory of“dynamic-...Objective:To investigate the clinical efficacy and safety of percutaneous kyphoplasty at different surgical timings in the treatment of osteoporotic vertebral compression fracture(OVCF)based on the theory of“dynamic-static integration”.Methods:Patients with OVCF who underwent percutaneous kyphoplasty in our hospital were selected and divided into Groups A,B,and C for those undergoing surgery within 7,7—21,and>21 days of fracture occurrence.The variations in the amount of bone cement injected,pre-and post-operative pain levels,functional activity,deformity correction of the injured vertebrae,bone cement leakage,and vertebral body height loss were compared among the three groups.Results:Regarding pain relief and functional activity,the postoperative Visual Analog Scale and Oswestry Disability Index scores of the three groups significantly improved.Furthermore,the deformities of the injured vertebrae in the three groups were significantly corrected,with Groups A and B exhibiting superior correction compared to Group C.Moreover,the bone cement leakage rates in groups A and C were higher than that in Group B.At the 3-month follow-up,the loss of vertebral height in Group C was significantly higher than those in groups A and B.Conclusion:Kyphoplasty is effective for OVCF treatment.Early surgery can effectively restore the vertebral height of the injured vertebra,reduce kyphosis,and reduce height loss of the injured vertebra after surgery;nevertheless,treatment within 1—3 weeks of the fracture can reduce the occurrence of bone cement leakage,making the surgery safer.Therefore,surgical treatment within 1—3 weeks of fracture is safer and can achieve satisfactory therapeutic effects.From the perspective of traditional Chinese medicine,PKP surgery can transform the fracture end from a micromotion state to a fixed state,which fully embodies the theory of“dynamic-static integration”.展开更多
After spinal cord injury,impairment of the sensorimotor circuit can lead to dysfunction in the motor,sensory,proprioceptive,and autonomic nervous systems.Functional recovery is often hindered by constraints on the tim...After spinal cord injury,impairment of the sensorimotor circuit can lead to dysfunction in the motor,sensory,proprioceptive,and autonomic nervous systems.Functional recovery is often hindered by constraints on the timing of interventions,combined with the limitations of current methods.To address these challenges,various techniques have been developed to aid in the repair and reconstruction of neural circuits at different stages of injury.Notably,neuromodulation has garnered considerable attention for its potential to enhance nerve regeneration,provide neuroprotection,restore neurons,and regulate the neural reorganization of circuits within the cerebral cortex and corticospinal tract.To improve the effectiveness of these interventions,the implementation of multitarget early interventional neuromodulation strategies,such as electrical and magnetic stimulation,is recommended to enhance functional recovery across different phases of nerve injury.This review concisely outlines the challenges encountered following spinal cord injury,synthesizes existing neurostimulation techniques while emphasizing neuroprotection,repair,and regeneration of impaired connections,and advocates for multi-targeted,task-oriented,and timely interventions.展开更多
A series of blue and blue‑green Ir(Ⅲ)complexes has been investigated theoretically to explore their electronic structures,photophysical properties,efficiency roll‑off effect,and thermal activation delayed fluorescenc...A series of blue and blue‑green Ir(Ⅲ)complexes has been investigated theoretically to explore their electronic structures,photophysical properties,efficiency roll‑off effect,and thermal activation delayed fluorescence(TADF)properties.All calculations were performed using density functional theory(DFT)and time‑dependent density functional theory(TDDFT).Calculations for electronic structures,frontier molecular orbital characteristics(which determine the efficiency roll‑off effect of the complexes),and photophysical properties were conducted using the Gaussian 09 software package.The calculation of spin‑orbit coupling matrix elements<T|HSOC|S>,which determine the TADF properties of the complexes,was performed using the ORCA software package.The calculation results show that the auxiliary ligand tetraphenylimidodiphosphinate(tpip),a strong electron‑withdrawing group,can mitigate the efficiency roll‑off effect of the complex.Furthermore,TADF is observed in one of the designed complexes,(F_(3)Phppy)_(2)Ir(tpip),where F_(3)Phppy=2‑[4‑(2,4,6‑trifluorophenyl)phenyl]pyridine.展开更多
AIM:To compare the tear film quantity and stability parameters in keratoconus(KCN)and normal eyes using test breakup time(TBUT),noninvasive TBUT(NITBUT),and Schirmer test.METHODS:All participants(n=166),including pati...AIM:To compare the tear film quantity and stability parameters in keratoconus(KCN)and normal eyes using test breakup time(TBUT),noninvasive TBUT(NITBUT),and Schirmer test.METHODS:All participants(n=166),including patients with KCN and age-matched healthy individuals with normal corneas,were recruited from those referred to Farabi Eye Hospital,Iran,in 2023.To better account for genetic and environmental factors,the control group comprised healthy individuals who were relatives of KCN patients and had normal corneal topography.Tear quantity parameters were evaluated in the following order:NITBUT,TBUT,and Schirmer tests.RESULTS:The mean age of cases in KCN(61.7%males)and normal(63.5%males)participants was 27.54±5.44y(range 19 to 38)and 27.52±5.63y(range 20 to 38),respectively(P=0.976).NIBUT,TBUT,and Schirmer’s tests were significantly lower in KCN group compared to normal controls(all P<0.001).The mean difference for NIBUT was-7.81s(P<0.001),and for TBUT was-7.61s(P<0.001).Schirmer test values were also significantly lower in the KCN group,with a mean difference of-5.61 mm compared to normal people(P<0.001).CONCLUSION:Our findings demonstrate significant tear film impairment in KCN.The reductions in NIBUT,TBUT and Schirmer scores highlight an underlying tear film dysfunction in KCN that extends beyond the morphological changes of the cornea.展开更多
The Shanghai High Repetition Rate XFEL and Extreme Light Facility(SHINE)is currently under construction as one of the world’s most advanced hard X-ray free-electron laser facilities.The timing system,as an essential ...The Shanghai High Repetition Rate XFEL and Extreme Light Facility(SHINE)is currently under construction as one of the world’s most advanced hard X-ray free-electron laser facilities.The timing system,as an essential part of the free-electron laser facility,provides precise timing of trigger pulse signals for a range of devices to ensure that particles are generated and accelerated to the designed energy while enabling the precise measurement of beam parameters.To precisely distribute and synchronize the 1.003086 MHz(1300/1296)timing signals over a distance of approximately 3.1 km based on White Rabbit technology,three technical routes have been proposed.This paper begins with a description of the design and development process of the timing system for the SHINE project,which culminates with the determination of the design scheme.During the installation and commissioning of the timing system,the jitter accuracy of the timing signal was tested and found to be less than 10 ps,which meets the requirements of the project.Furthermore,the precise clock synchronization signal provided by the timing system supported the joint debugging of various related systems and realization of beam acquisition.展开更多
Field-effect nanofluidic transistors(FENTs),biomimicking the structure and functionality of neuron,act as biological transistors with the ability to gate switching responses to external stimuli.The switching ratio has...Field-effect nanofluidic transistors(FENTs),biomimicking the structure and functionality of neuron,act as biological transistors with the ability to gate switching responses to external stimuli.The switching ratio has been verified to evaluate the performance of FENTs,but until recently,the response time,another crucial indicator,has been ignored.Employing finite-element method,we investigated the relationship among gate charge,switching ratio and response time by divisionally manipulating gate charge,including entrance surface and the surface of confinement space,for ion transport to optimize switching capability.The dual-split gate charge on FENTs exhibits synergistic effect on switching response.Based on the two regional gate charge on FENTs,multivalence ions in lower concentration,high aspect ratio and single channel show higher switching ratio but longer response time compared to monovalent ions.The findings highlight the necessity of balancing these two signals in FENTs and offer insights for optimizing their design and expanding applications to dual-signal-detection iontronics.展开更多
A 32-channel charge-sensitive amplifier(CSA)is designed for fast timing in the delay-line readout of a parallel plate avalanche counter(PPAC)array.It is realized on a PCB with operational amplifiers and other discrete...A 32-channel charge-sensitive amplifier(CSA)is designed for fast timing in the delay-line readout of a parallel plate avalanche counter(PPAC)array.It is realized on a PCB with operational amplifiers and other discrete components.Each channel consists of an integrator,a pole-zero cancellation net,and a linear amplification stage,which can be adapted to accommodate either positive or negative input signals.The RMS equivalent input noise charges are 3.3 fC,the conversion gains are approximately±2 mV∕fC,and the intrinsic time resolution reaches 32 ps.In the prototype PPAC application,the CSA performs as well as the commercial FTA820A amplifier,providing a position resolution as good as 0.17 mm,and exhibiting reliable stability during several hours of continuous data acquisition.展开更多
Severe trauma often involves complex injuries,leading to high disability and fatality rates.Effective treatment requires prompt and coordinated efforts across multiple disciplines to enhance success rates.Time-based c...Severe trauma often involves complex injuries,leading to high disability and fatality rates.Effective treatment requires prompt and coordinated efforts across multiple disciplines to enhance success rates.Time-based chain rescue is crucial in managing severe trauma.A patient with chest and abdominal injuries and hemorrhagic shock was transferred from an ambulance to our hospital.Our trauma team-initiated pre-hospital first aid,utilized an emergency green channel,and conducted rapid ultrasound,collaborating across disciplines.The patient eventually recovered and was discharged.展开更多
The susceptibility of ore particles to electrical breakdown plays a critical role for high voltage pulse(HVP)breakage,yet its quantitative characterization still lacks deep understanding.Two indicators,namely breakdow...The susceptibility of ore particles to electrical breakdown plays a critical role for high voltage pulse(HVP)breakage,yet its quantitative characterization still lacks deep understanding.Two indicators,namely breakdown delay time(T_(d))and breakdown strength(E_(b))were compared,based on analysis on the two breakdown modes namely wavefront mode and post-wave mode.It was found that T_(d) is more suitable to characterize the susceptibility of ore particles to electrical breakdown in HVP breakage than E_(b).A probabilistic model based on the Weibull distribution is developed to describe the relation of breakdown probability to T_(d).Regression analyses were conducted to investigate how operating parameters and particle properties influence Td and size reduction degree of ore particles in HVP breakage.The regressed models demonstrate potential capability to predict metallic minerals content and HVP breakage degree based on operating parameters and particle properties.展开更多
Safer,smarter,faster...In China,people prefer high-speed trains to flights if the journey time is under five hours.High-speed train travel is set to become even more attractive with the addition of a new member to the...Safer,smarter,faster...In China,people prefer high-speed trains to flights if the journey time is under five hours.High-speed train travel is set to become even more attractive with the addition of a new member to the high-speed train family:the CR450,the world’s fastest electric multiple unit(EMU).展开更多
A RadioFrequency Quadrupole(RFQ)cooler-buncher system was developed and implemented in a collinear laser spectroscopy setup.This system converts a continuous ion beam into short bunches while enhancing the beam qualit...A RadioFrequency Quadrupole(RFQ)cooler-buncher system was developed and implemented in a collinear laser spectroscopy setup.This system converts a continuous ion beam into short bunches while enhancing the beam quality and reducing the energy spread.The functionality of the RFQ cooler buncher was verified through offline tests with stable rubidium and indium beams delivered from a surface ion source and a laser ablation ion source,respectively.Bunched ion beams with a full width at half maximum of approximately 2μs in the time-of-flight spectrum were successfully achieved with a transmission efficiency exceeding 60%.The implementation of the RFQ cooler-buncher system also significantly improved the overall transmission efficiency of the collinear laser spectroscopy setup.展开更多
Covert timing channels(CTC)exploit network resources to establish hidden communication pathways,posing signi cant risks to data security and policy compliance.erefore,detecting such hidden and dangerous threats remain...Covert timing channels(CTC)exploit network resources to establish hidden communication pathways,posing signi cant risks to data security and policy compliance.erefore,detecting such hidden and dangerous threats remains one of the security challenges. is paper proposes LinguTimeX,a new framework that combines natural language processing with arti cial intelligence,along with explainable Arti cial Intelligence(AI)not only to detect CTC but also to provide insights into the decision process.LinguTimeX performs multidimensional feature extraction by fusing linguistic attributes with temporal network patterns to identify covert channels precisely.LinguTimeX demonstrates strong e ectiveness in detecting CTC across multiple languages;namely English,Arabic,and Chinese.Speci cally,the LSTM and RNN models achieved F1 scores of 90%on the English dataset,89%on the Arabic dataset,and 88%on the Chinese dataset,showcasing their superior performance and ability to generalize across multiple languages. is highlights their robustness in detecting CTCs within security systems,regardless of the language or cultural context of the data.In contrast,the DeepForest model produced F1-scores ranging from 86%to 87%across the same datasets,further con rming its e ectiveness in CTC detection.Although other algorithms also showed reasonable accuracy,the LSTM and RNN models consistently outperformed them in multilingual settings,suggesting that deep learning models might be better suited for this particular problem.展开更多
Time-delayed blasting is widely utilized in engineering to mitigate induced vibration hazards and enhance fragmentation.The underlying vibration reduction principle is the decrease of the charge weight per delay,while...Time-delayed blasting is widely utilized in engineering to mitigate induced vibration hazards and enhance fragmentation.The underlying vibration reduction principle is the decrease of the charge weight per delay,while the potential for further vibration reduction remains debated,largely due to unclear underlying mechanisms.In light of the popularization of electronic detonators and the representativeness of double-hole configurationsfor multiple blastholes,it is essential to investigate the vibration characteristics induced by time-delayed double blastholes.Therefore,a series of doubleborehole experimental blasts was conducted in an underground roadway to clarify the variation in vibration from single-hole to dual-hole conditions.Based on the experimental data and inherent limitations,an exact full-fieldtheoretical model was further employed to systematically analyze the effects of delay time,charge length,and borehole inclination angle on vibrations induced by various doublehole configurations.The experimental data and theoretical analysis reveal that the general scaled distance effectively predicts vibrations in delayed blasting but does not reflectvibration reduction.Increasing delay time causes fluctuatingPPVs,which stabilize slightly above single-hole PPVs as delay times exceed a certain value.The delayed blasting primarily reduces near-fieldfrequencies.Longer charge lengths in double boreholes increase PPV levels and attenuation rates within a certain length,and the vibration behavior of combined long and short charge lengths is governed by the long blasthole.Larger blasthole inclination angles enhance vibration amplitude and reduce PPV attenuation rates.Optimizing inclination angles is more critical than adjusting delay times,and parallel boreholes offer the best vibration control.展开更多
This study proposes a novel forecasting framework that simultaneously captures the strong periodicity and irregular meteorological fluctuations inherent in solar radiation time series.Existing approaches typically def...This study proposes a novel forecasting framework that simultaneously captures the strong periodicity and irregular meteorological fluctuations inherent in solar radiation time series.Existing approaches typically define inter-regional correlations using either simple correlation coefficients or distance-based measures when applying spatio-temporal graph neural networks(STGNNs).However,such definitions are prone to generating spurious correlations due to the dominance of periodic structures.To address this limitation,we adopt the Elastic-Band Transform(EBT)to decompose solar radiation into periodic and amplitude-modulated components,which are then modeled independently with separate graph neural networks.The periodic component,characterized by strong nationwide correlations,is learned with a relatively simple architecture,whereas the amplitude-modulated component is modeled with more complex STGNNs that capture climatological similarities between regions.The predictions from the two components are subsequently recombined to yield final forecasts that integrate both periodic patterns and aperiodic variability.The proposed framework is validated with multiple STGNN architectures,and experimental results demonstrate improved predictive accuracy and interpretability compared to conventional methods.展开更多
Precipitation events,which follow a life cycle of initiation,development,and decay,represent the fundamental form of precipitation.Comprehensive and accurate detection of these events is crucial for effective water re...Precipitation events,which follow a life cycle of initiation,development,and decay,represent the fundamental form of precipitation.Comprehensive and accurate detection of these events is crucial for effective water resource management and flood control.However,current investigations on their spatio-temporal patterns remain limited,largely because of the lack of systematic detection indices that are specifically designed for precipitation events,which constrains event-scale research.In this study,we defined a set of precipitation event detection indices(PEDI)that consists of five conventional and fourteen extreme indices to characterize precipitation events from the perspectives of intensity,duration,and frequency.Applications of the PEDI revealed the spatial patterns of hourly precipitation events in China and its first-and second-order river basins from 2008 to 2017.Both conventional and extreme precipitation events displayed spatial distribution patterns that gradually decreased in intensity,duration,and frequency from southeast to northwest China.Compared with those in northwest China,the average values of most PEDIs in southeast China were usually 2-10 times greater for first-order river basins and 3-15 times greater for second-order basins.The PEDI could serve as a reference method for investigating precipitation events at global,regional,and basin scales.展开更多
Predicting the behavior of renewable energy systems requires models capable of generating accurate forecasts from limited historical data,a challenge that becomes especially pronounced when commissioning new facil-iti...Predicting the behavior of renewable energy systems requires models capable of generating accurate forecasts from limited historical data,a challenge that becomes especially pronounced when commissioning new facil-ities where operational records are scarce.This review aims to synthesize recent progress in data-efficient deep learning approaches for addressing such“cold-start”forecasting problems.It primarily covers three interrelated domains—solar photovoltaic(PV),wind power,and electrical load forecasting—where data scarcity and operational variability are most critical,while also including representative studies on hydropower and carbon emission prediction to provide a broader systems perspective.To this end,we examined trends from over 150 predominantly peer-reviewed studies published between 2019 and mid-2025,highlighting advances in zero-shot and few-shot meta-learning frameworks that enable rapid model adaptation with minimal labeled data.Moreover,transfer learning approaches combined with spatiotemporal graph neural networks have been employed to transfer knowledge from existing energy assets to new,data-sparse environments,effectively capturing hidden dependencies among geographic features,meteorological dynamics,and grid structures.Synthetic data generation has further proven valuable for expanding training samples and mitigating overfitting in cold-start scenarios.In addition,large language models and explainable artificial intelligence(XAI)—notably conversational XAI systems—have been used to interpret and communicate complex model behaviors in accessible terms,fostering operator trust from the earliest deployment stages.By consolidating methodological advances,unresolved challenges,and open-source resources,this review provides a coherent overview of deep learning strategies that can shorten the data-sparse ramp-up period of new energy infrastructures and accelerate the transition toward resilient,low-carbon electricity grids.展开更多
基金supported by the National Natural Science Foundation of China(82374493).
文摘Objective:To investigate the clinical efficacy and safety of percutaneous kyphoplasty at different surgical timings in the treatment of osteoporotic vertebral compression fracture(OVCF)based on the theory of“dynamic-static integration”.Methods:Patients with OVCF who underwent percutaneous kyphoplasty in our hospital were selected and divided into Groups A,B,and C for those undergoing surgery within 7,7—21,and>21 days of fracture occurrence.The variations in the amount of bone cement injected,pre-and post-operative pain levels,functional activity,deformity correction of the injured vertebrae,bone cement leakage,and vertebral body height loss were compared among the three groups.Results:Regarding pain relief and functional activity,the postoperative Visual Analog Scale and Oswestry Disability Index scores of the three groups significantly improved.Furthermore,the deformities of the injured vertebrae in the three groups were significantly corrected,with Groups A and B exhibiting superior correction compared to Group C.Moreover,the bone cement leakage rates in groups A and C were higher than that in Group B.At the 3-month follow-up,the loss of vertebral height in Group C was significantly higher than those in groups A and B.Conclusion:Kyphoplasty is effective for OVCF treatment.Early surgery can effectively restore the vertebral height of the injured vertebra,reduce kyphosis,and reduce height loss of the injured vertebra after surgery;nevertheless,treatment within 1—3 weeks of the fracture can reduce the occurrence of bone cement leakage,making the surgery safer.Therefore,surgical treatment within 1—3 weeks of fracture is safer and can achieve satisfactory therapeutic effects.From the perspective of traditional Chinese medicine,PKP surgery can transform the fracture end from a micromotion state to a fixed state,which fully embodies the theory of“dynamic-static integration”.
基金supported by the National Key Research and Development Program of China,No.2023YFC3603705(to DX)the National Natural Science Foundation of China,No.82302866(to YZ).
文摘After spinal cord injury,impairment of the sensorimotor circuit can lead to dysfunction in the motor,sensory,proprioceptive,and autonomic nervous systems.Functional recovery is often hindered by constraints on the timing of interventions,combined with the limitations of current methods.To address these challenges,various techniques have been developed to aid in the repair and reconstruction of neural circuits at different stages of injury.Notably,neuromodulation has garnered considerable attention for its potential to enhance nerve regeneration,provide neuroprotection,restore neurons,and regulate the neural reorganization of circuits within the cerebral cortex and corticospinal tract.To improve the effectiveness of these interventions,the implementation of multitarget early interventional neuromodulation strategies,such as electrical and magnetic stimulation,is recommended to enhance functional recovery across different phases of nerve injury.This review concisely outlines the challenges encountered following spinal cord injury,synthesizes existing neurostimulation techniques while emphasizing neuroprotection,repair,and regeneration of impaired connections,and advocates for multi-targeted,task-oriented,and timely interventions.
文摘A series of blue and blue‑green Ir(Ⅲ)complexes has been investigated theoretically to explore their electronic structures,photophysical properties,efficiency roll‑off effect,and thermal activation delayed fluorescence(TADF)properties.All calculations were performed using density functional theory(DFT)and time‑dependent density functional theory(TDDFT).Calculations for electronic structures,frontier molecular orbital characteristics(which determine the efficiency roll‑off effect of the complexes),and photophysical properties were conducted using the Gaussian 09 software package.The calculation of spin‑orbit coupling matrix elements<T|HSOC|S>,which determine the TADF properties of the complexes,was performed using the ORCA software package.The calculation results show that the auxiliary ligand tetraphenylimidodiphosphinate(tpip),a strong electron‑withdrawing group,can mitigate the efficiency roll‑off effect of the complex.Furthermore,TADF is observed in one of the designed complexes,(F_(3)Phppy)_(2)Ir(tpip),where F_(3)Phppy=2‑[4‑(2,4,6‑trifluorophenyl)phenyl]pyridine.
文摘AIM:To compare the tear film quantity and stability parameters in keratoconus(KCN)and normal eyes using test breakup time(TBUT),noninvasive TBUT(NITBUT),and Schirmer test.METHODS:All participants(n=166),including patients with KCN and age-matched healthy individuals with normal corneas,were recruited from those referred to Farabi Eye Hospital,Iran,in 2023.To better account for genetic and environmental factors,the control group comprised healthy individuals who were relatives of KCN patients and had normal corneal topography.Tear quantity parameters were evaluated in the following order:NITBUT,TBUT,and Schirmer tests.RESULTS:The mean age of cases in KCN(61.7%males)and normal(63.5%males)participants was 27.54±5.44y(range 19 to 38)and 27.52±5.63y(range 20 to 38),respectively(P=0.976).NIBUT,TBUT,and Schirmer’s tests were significantly lower in KCN group compared to normal controls(all P<0.001).The mean difference for NIBUT was-7.81s(P<0.001),and for TBUT was-7.61s(P<0.001).Schirmer test values were also significantly lower in the KCN group,with a mean difference of-5.61 mm compared to normal people(P<0.001).CONCLUSION:Our findings demonstrate significant tear film impairment in KCN.The reductions in NIBUT,TBUT and Schirmer scores highlight an underlying tear film dysfunction in KCN that extends beyond the morphological changes of the cornea.
基金supported by SHINE and Shanghai Municipal Science and Technology Major Project(No.2017SHZDZX02).
文摘The Shanghai High Repetition Rate XFEL and Extreme Light Facility(SHINE)is currently under construction as one of the world’s most advanced hard X-ray free-electron laser facilities.The timing system,as an essential part of the free-electron laser facility,provides precise timing of trigger pulse signals for a range of devices to ensure that particles are generated and accelerated to the designed energy while enabling the precise measurement of beam parameters.To precisely distribute and synchronize the 1.003086 MHz(1300/1296)timing signals over a distance of approximately 3.1 km based on White Rabbit technology,three technical routes have been proposed.This paper begins with a description of the design and development process of the timing system for the SHINE project,which culminates with the determination of the design scheme.During the installation and commissioning of the timing system,the jitter accuracy of the timing signal was tested and found to be less than 10 ps,which meets the requirements of the project.Furthermore,the precise clock synchronization signal provided by the timing system supported the joint debugging of various related systems and realization of beam acquisition.
基金supported by the Natural Science Foundation of Guangdong Province,China (No.2025A1515011654)the National Natural Science Foundation of China (No.22090053)+3 种基金the Fundamental Research Funds for National Universities,China University of Geosciences (Wuhan)support from the program of China Scholarships Council (No.202406410155)Young Elite Scientists Sponsorship Program by CAST-Doctoral Student Special Plansupport from the S&T Special Program of Huzhou (No.2024GZ07)。
文摘Field-effect nanofluidic transistors(FENTs),biomimicking the structure and functionality of neuron,act as biological transistors with the ability to gate switching responses to external stimuli.The switching ratio has been verified to evaluate the performance of FENTs,but until recently,the response time,another crucial indicator,has been ignored.Employing finite-element method,we investigated the relationship among gate charge,switching ratio and response time by divisionally manipulating gate charge,including entrance surface and the surface of confinement space,for ion transport to optimize switching capability.The dual-split gate charge on FENTs exhibits synergistic effect on switching response.Based on the two regional gate charge on FENTs,multivalence ions in lower concentration,high aspect ratio and single channel show higher switching ratio but longer response time compared to monovalent ions.The findings highlight the necessity of balancing these two signals in FENTs and offer insights for optimizing their design and expanding applications to dual-signal-detection iontronics.
基金supported by the National Natural Science Foundation of China(Nos.U2167202,12225504,12005276)the Natural Science Foundation of Shandong Province(No.ZR2024QA172)the Fundamental Research Funds of Shandong University.
文摘A 32-channel charge-sensitive amplifier(CSA)is designed for fast timing in the delay-line readout of a parallel plate avalanche counter(PPAC)array.It is realized on a PCB with operational amplifiers and other discrete components.Each channel consists of an integrator,a pole-zero cancellation net,and a linear amplification stage,which can be adapted to accommodate either positive or negative input signals.The RMS equivalent input noise charges are 3.3 fC,the conversion gains are approximately±2 mV∕fC,and the intrinsic time resolution reaches 32 ps.In the prototype PPAC application,the CSA performs as well as the commercial FTA820A amplifier,providing a position resolution as good as 0.17 mm,and exhibiting reliable stability during several hours of continuous data acquisition.
基金Jiangsu Provincial Hospital Association Hospital Management Innovation Research Fund(Project Ni.:JSYGY-3-2025-267)。
文摘Severe trauma often involves complex injuries,leading to high disability and fatality rates.Effective treatment requires prompt and coordinated efforts across multiple disciplines to enhance success rates.Time-based chain rescue is crucial in managing severe trauma.A patient with chest and abdominal injuries and hemorrhagic shock was transferred from an ambulance to our hospital.Our trauma team-initiated pre-hospital first aid,utilized an emergency green channel,and conducted rapid ultrasound,collaborating across disciplines.The patient eventually recovered and was discharged.
基金The financial supports from National Natural Science Foundation of China(Nos.52574313,52204272 and 52074091)to this project。
文摘The susceptibility of ore particles to electrical breakdown plays a critical role for high voltage pulse(HVP)breakage,yet its quantitative characterization still lacks deep understanding.Two indicators,namely breakdown delay time(T_(d))and breakdown strength(E_(b))were compared,based on analysis on the two breakdown modes namely wavefront mode and post-wave mode.It was found that T_(d) is more suitable to characterize the susceptibility of ore particles to electrical breakdown in HVP breakage than E_(b).A probabilistic model based on the Weibull distribution is developed to describe the relation of breakdown probability to T_(d).Regression analyses were conducted to investigate how operating parameters and particle properties influence Td and size reduction degree of ore particles in HVP breakage.The regressed models demonstrate potential capability to predict metallic minerals content and HVP breakage degree based on operating parameters and particle properties.
文摘Safer,smarter,faster...In China,people prefer high-speed trains to flights if the journey time is under five hours.High-speed train travel is set to become even more attractive with the addition of a new member to the high-speed train family:the CR450,the world’s fastest electric multiple unit(EMU).
基金supported by the National Natural Science Foundation of China(Nos.12027809,12350007)National Key R&D Program of China(Nos.2022YFA1605100,2023YFA1606403,and 2023YFE0101600)+1 种基金New Cornerstone Science Foundation through the XPLORER PRIZEfunding from the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation program under grant agreement No.679038.
文摘A RadioFrequency Quadrupole(RFQ)cooler-buncher system was developed and implemented in a collinear laser spectroscopy setup.This system converts a continuous ion beam into short bunches while enhancing the beam quality and reducing the energy spread.The functionality of the RFQ cooler buncher was verified through offline tests with stable rubidium and indium beams delivered from a surface ion source and a laser ablation ion source,respectively.Bunched ion beams with a full width at half maximum of approximately 2μs in the time-of-flight spectrum were successfully achieved with a transmission efficiency exceeding 60%.The implementation of the RFQ cooler-buncher system also significantly improved the overall transmission efficiency of the collinear laser spectroscopy setup.
基金This study is financed by the European Union-NextGenerationEU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,Project No.BG-RRP-2.013-0001.
文摘Covert timing channels(CTC)exploit network resources to establish hidden communication pathways,posing signi cant risks to data security and policy compliance.erefore,detecting such hidden and dangerous threats remains one of the security challenges. is paper proposes LinguTimeX,a new framework that combines natural language processing with arti cial intelligence,along with explainable Arti cial Intelligence(AI)not only to detect CTC but also to provide insights into the decision process.LinguTimeX performs multidimensional feature extraction by fusing linguistic attributes with temporal network patterns to identify covert channels precisely.LinguTimeX demonstrates strong e ectiveness in detecting CTC across multiple languages;namely English,Arabic,and Chinese.Speci cally,the LSTM and RNN models achieved F1 scores of 90%on the English dataset,89%on the Arabic dataset,and 88%on the Chinese dataset,showcasing their superior performance and ability to generalize across multiple languages. is highlights their robustness in detecting CTCs within security systems,regardless of the language or cultural context of the data.In contrast,the DeepForest model produced F1-scores ranging from 86%to 87%across the same datasets,further con rming its e ectiveness in CTC detection.Although other algorithms also showed reasonable accuracy,the LSTM and RNN models consistently outperformed them in multilingual settings,suggesting that deep learning models might be better suited for this particular problem.
基金supported by the National Natural Science Foundation of China(Grant Nos.42407267 and 52374152)the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20220975).
文摘Time-delayed blasting is widely utilized in engineering to mitigate induced vibration hazards and enhance fragmentation.The underlying vibration reduction principle is the decrease of the charge weight per delay,while the potential for further vibration reduction remains debated,largely due to unclear underlying mechanisms.In light of the popularization of electronic detonators and the representativeness of double-hole configurationsfor multiple blastholes,it is essential to investigate the vibration characteristics induced by time-delayed double blastholes.Therefore,a series of doubleborehole experimental blasts was conducted in an underground roadway to clarify the variation in vibration from single-hole to dual-hole conditions.Based on the experimental data and inherent limitations,an exact full-fieldtheoretical model was further employed to systematically analyze the effects of delay time,charge length,and borehole inclination angle on vibrations induced by various doublehole configurations.The experimental data and theoretical analysis reveal that the general scaled distance effectively predicts vibrations in delayed blasting but does not reflectvibration reduction.Increasing delay time causes fluctuatingPPVs,which stabilize slightly above single-hole PPVs as delay times exceed a certain value.The delayed blasting primarily reduces near-fieldfrequencies.Longer charge lengths in double boreholes increase PPV levels and attenuation rates within a certain length,and the vibration behavior of combined long and short charge lengths is governed by the long blasthole.Larger blasthole inclination angles enhance vibration amplitude and reduce PPV attenuation rates.Optimizing inclination angles is more critical than adjusting delay times,and parallel boreholes offer the best vibration control.
基金supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(RS-2023-00249743).
文摘This study proposes a novel forecasting framework that simultaneously captures the strong periodicity and irregular meteorological fluctuations inherent in solar radiation time series.Existing approaches typically define inter-regional correlations using either simple correlation coefficients or distance-based measures when applying spatio-temporal graph neural networks(STGNNs).However,such definitions are prone to generating spurious correlations due to the dominance of periodic structures.To address this limitation,we adopt the Elastic-Band Transform(EBT)to decompose solar radiation into periodic and amplitude-modulated components,which are then modeled independently with separate graph neural networks.The periodic component,characterized by strong nationwide correlations,is learned with a relatively simple architecture,whereas the amplitude-modulated component is modeled with more complex STGNNs that capture climatological similarities between regions.The predictions from the two components are subsequently recombined to yield final forecasts that integrate both periodic patterns and aperiodic variability.The proposed framework is validated with multiple STGNN architectures,and experimental results demonstrate improved predictive accuracy and interpretability compared to conventional methods.
基金National Key Research and Development Program of China,No.2023YFC3206605,No.2021YFC3201102National Natural Science Foundation of China,No.41971035。
文摘Precipitation events,which follow a life cycle of initiation,development,and decay,represent the fundamental form of precipitation.Comprehensive and accurate detection of these events is crucial for effective water resource management and flood control.However,current investigations on their spatio-temporal patterns remain limited,largely because of the lack of systematic detection indices that are specifically designed for precipitation events,which constrains event-scale research.In this study,we defined a set of precipitation event detection indices(PEDI)that consists of five conventional and fourteen extreme indices to characterize precipitation events from the perspectives of intensity,duration,and frequency.Applications of the PEDI revealed the spatial patterns of hourly precipitation events in China and its first-and second-order river basins from 2008 to 2017.Both conventional and extreme precipitation events displayed spatial distribution patterns that gradually decreased in intensity,duration,and frequency from southeast to northwest China.Compared with those in northwest China,the average values of most PEDIs in southeast China were usually 2-10 times greater for first-order river basins and 3-15 times greater for second-order basins.The PEDI could serve as a reference method for investigating precipitation events at global,regional,and basin scales.
文摘Predicting the behavior of renewable energy systems requires models capable of generating accurate forecasts from limited historical data,a challenge that becomes especially pronounced when commissioning new facil-ities where operational records are scarce.This review aims to synthesize recent progress in data-efficient deep learning approaches for addressing such“cold-start”forecasting problems.It primarily covers three interrelated domains—solar photovoltaic(PV),wind power,and electrical load forecasting—where data scarcity and operational variability are most critical,while also including representative studies on hydropower and carbon emission prediction to provide a broader systems perspective.To this end,we examined trends from over 150 predominantly peer-reviewed studies published between 2019 and mid-2025,highlighting advances in zero-shot and few-shot meta-learning frameworks that enable rapid model adaptation with minimal labeled data.Moreover,transfer learning approaches combined with spatiotemporal graph neural networks have been employed to transfer knowledge from existing energy assets to new,data-sparse environments,effectively capturing hidden dependencies among geographic features,meteorological dynamics,and grid structures.Synthetic data generation has further proven valuable for expanding training samples and mitigating overfitting in cold-start scenarios.In addition,large language models and explainable artificial intelligence(XAI)—notably conversational XAI systems—have been used to interpret and communicate complex model behaviors in accessible terms,fostering operator trust from the earliest deployment stages.By consolidating methodological advances,unresolved challenges,and open-source resources,this review provides a coherent overview of deep learning strategies that can shorten the data-sparse ramp-up period of new energy infrastructures and accelerate the transition toward resilient,low-carbon electricity grids.