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Time-varying networks based on activation and deactivation mechanisms 被引量:1
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作者 王学文 罗月娥 +1 位作者 张丽杰 许新建 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第10期527-532,共6页
A class of models for activity-driven networks is proposed in which nodes vary in two states: active and inactive. Only active nodes can receive links from others which represent instantaneous dynamical interactions.... A class of models for activity-driven networks is proposed in which nodes vary in two states: active and inactive. Only active nodes can receive links from others which represent instantaneous dynamical interactions. The evolution of the network couples the addition of new nodes and state transitions of old ones. The active group changes with activated nodes entering and deactivated ones leaving. A general differential equation framework is developed to study the degree distribution of nodes of integrated networks where four different schemes are formulated. 展开更多
关键词 time-varying networks activity-driven degree distribution
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Finite time hybrid synchronization of heterogeneous duplex complex networks via time-varying intermittent control
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作者 Cheng-Jun Xie Xiang-Qing Lu 《Chinese Physics B》 2025年第4期354-363,共10页
This paper study the finite time internal synchronization and the external synchronization(hybrid synchronization)for duplex heterogeneous complex networks by time-varying intermittent control.There few study hybrid s... This paper study the finite time internal synchronization and the external synchronization(hybrid synchronization)for duplex heterogeneous complex networks by time-varying intermittent control.There few study hybrid synchronization of heterogeneous duplex complex networks.Therefore,we study the finite time hybrid synchronization of heterogeneous duplex networks,which employs the time-varying intermittent control to drive the duplex heterogeneous complex networks to achieve hybrid synchronization in finite time.To be specific,the switch frequency of the controllers can be changed with time by devise Lyapunov function and boundary function,the internal synchronization and external synchronization are achieved simultaneously in finite time.Finally,numerical examples are presented to illustrate the validness of theoretical results. 展开更多
关键词 finite time synchronization time-varying intermittent control duplex heterogeneous networks complex networks
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Modified Fixed-Time Synchronization Criteria of Complex Networks with Time-Varying Delays via Continuous or Discontinuous Control
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作者 WU Huan WU Ailong ZHANG Jin'e 《Wuhan University Journal of Natural Sciences》 2025年第2期150-158,共9页
This paper investigates modified fixed-time synchronization(FxTS)of complex networks(CNs)with time-varying delays based on continuous and discontinuous controllers.First,for the sake of making the settling time(ST)of ... This paper investigates modified fixed-time synchronization(FxTS)of complex networks(CNs)with time-varying delays based on continuous and discontinuous controllers.First,for the sake of making the settling time(ST)of FxTS is independent of the initial values and parameters of the CNs,a modified fixed-time(FxT)stability theorem is proposed,where the ST is determined by an arbitrary positive number given in advance.Then,continuous controller and discontinuous controller are designed to realize the modified FxTS target of CNs.In addition,based on the designed controllers,CNs can achieve synchronization at any given time,or even earlier.And control strategies effectively solve the problem of ST related to the parameters of CNs.Finally,an appropriate simulation example is conducted to examine the effectiveness of the designed control strategies. 展开更多
关键词 complex networks settling time fixed-time synchronization controllers time-varying delays
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A Multi-Timescale Characteristics Analysis of the Network Power Response Excited by Voltage with Time-Varying Amplitude and Frequency
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作者 Jiabing Hu Weizhong Wen +2 位作者 Yingbiao Li Xing Liu Jianbo Guo 《Engineering》 2025年第8期49-61,共13页
The dynamics of network power response play a crucial role in system stability.However,the integration of power electronic equipment leads to amplitude and angular frequency(abbreviated as"frequency")time-va... The dynamics of network power response play a crucial role in system stability.However,the integration of power electronic equipment leads to amplitude and angular frequency(abbreviated as"frequency")time-varying characteristics of the node voltage during dynamic processes.As a result,traditional calcu-lation methods for and characteristics of the power response of the network based on phasor and impe-dance lose their validity.Therefore,this paper undertakes mathematical calculations to reveal the power response of a network under excitation by voltage with time-varying amplitude and frequency(TVAF),relying on the original mathematical relationships and superimposed step response.Then,the multi-timescale characteristics of both the active and reactive power of the network are explored physically.Additionally,this paper reveals a new phenomenon of storing and releasing the active and reactive power of the network.To meet practical engineering requirements,a simplified power expression is presented.Finally,the theoretical analysis is validated through time-domain simulations. 展开更多
关键词 Power response of network Voltage with time-varying amplitude and frequency Multi-timescale characteristics Power electronic equipment
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Privacy Distributed Constrained Optimization Over Time-Varying Unbalanced Networks and Its Application in Federated Learning
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作者 Mengli Wei Wenwu Yu +2 位作者 Duxin Chen Mingyu Kang Guang Cheng 《IEEE/CAA Journal of Automatica Sinica》 2025年第2期335-346,共12页
This paper investigates a class of constrained distributed zeroth-order optimization(ZOO) problems over timevarying unbalanced graphs while ensuring privacy preservation among individual agents. Not taking into accoun... This paper investigates a class of constrained distributed zeroth-order optimization(ZOO) problems over timevarying unbalanced graphs while ensuring privacy preservation among individual agents. Not taking into account recent progress and addressing these concerns separately, there remains a lack of solutions offering theoretical guarantees for both privacy protection and constrained ZOO over time-varying unbalanced graphs.We hereby propose a novel algorithm, termed the differential privacy(DP) distributed push-sum based zeroth-order constrained optimization algorithm(DP-ZOCOA). Operating over time-varying unbalanced graphs, DP-ZOCOA obviates the need for supplemental suboptimization problem computations, thereby reducing overhead in comparison to distributed primary-dual methods. DP-ZOCOA is specifically tailored to tackle constrained ZOO problems over time-varying unbalanced graphs,offering a guarantee of convergence to the optimal solution while robustly preserving privacy. Moreover, we provide rigorous proofs of convergence and privacy for DP-ZOCOA, underscoring its efficacy in attaining optimal convergence without constraints. To enhance its applicability, we incorporate DP-ZOCOA into the federated learning framework and formulate a decentralized zeroth-order constrained federated learning algorithm(ZOCOA-FL) to address challenges stemming from the timevarying imbalance of communication topology. Finally, the performance and effectiveness of the proposed algorithms are thoroughly evaluated through simulations on distributed least squares(DLS) and decentralized federated learning(DFL) tasks. 展开更多
关键词 Constrained distributed optimization decentralized federated learning(DFL) differential privacy(DP) time-varying unbalanced graphs zeroth-order gradient
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Joint Optimization of Routing and Resource Allocation in Decentralized UAV Networks Based on DDQN and GNN
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作者 Nawaf Q.H.Othman YANG Qinghai JIANG Xinpei 《电讯技术》 北大核心 2026年第1期1-10,共10页
Optimizing routing and resource allocation in decentralized unmanned aerial vehicle(UAV)networks remains challenging due to interference and rapidly changing topologies.The authors introduce a novel framework combinin... Optimizing routing and resource allocation in decentralized unmanned aerial vehicle(UAV)networks remains challenging due to interference and rapidly changing topologies.The authors introduce a novel framework combining double deep Q-networks(DDQNs)and graph neural networks(GNNs)for joint routing and resource allocation.The framework uses GNNs to model the network topology and DDQNs to adaptively control routing and resource allocation,addressing interference and improving network performance.Simulation results show that the proposed approach outperforms traditional methods such as Closest-to-Destination(c2Dst),Max-SINR(mSINR),and Multi-Layer Perceptron(MLP)-based models,achieving approximately 23.5% improvement in throughput,50% increase in connection probability,and 17.6% reduction in number of hops,demonstrating its effectiveness in dynamic UAV networks. 展开更多
关键词 decentralized UAV network resource allocation routing algorithm GNN DDQN DRL
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Time-Varying Formation Tracking Control of Heterogeneous Multi-Agent Systems With Intermittent Communications and Directed Switching Networks
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作者 Yuhan Wang Zhuping Wang +1 位作者 Hao Zhang Huaicheng Yan 《IEEE/CAA Journal of Automatica Sinica》 2025年第1期294-296,共3页
Dear Editor,This letter is concerned with the problem of time-varying formation tracking for heterogeneous multi-agent systems(MASs) under directed switching networks. For this purpose, our first step is to present so... Dear Editor,This letter is concerned with the problem of time-varying formation tracking for heterogeneous multi-agent systems(MASs) under directed switching networks. For this purpose, our first step is to present some sufficient conditions for the exponential stability of a particular category of switched systems. 展开更多
关键词 switched systems time varying formation tracking directed switching networks heterogeneous multi agent systems intermittent communications exponential stability
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HGS-ATD:A Hybrid Graph Convolutional Network-GraphSAGE Model for Anomaly Traffic Detection
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作者 Zhian Cui Hailong Li Xieyang Shen 《Journal of Harbin Institute of Technology(New Series)》 2026年第1期33-50,共18页
With network attack technology continuing to develop,traditional anomaly traffic detection methods that rely on feature engineering are increasingly insufficient in efficiency and accuracy.Graph Neural Network(GNN),a ... With network attack technology continuing to develop,traditional anomaly traffic detection methods that rely on feature engineering are increasingly insufficient in efficiency and accuracy.Graph Neural Network(GNN),a promising Deep Learning(DL)approach,has proven to be highly effective in identifying intricate patterns in graph⁃structured data and has already found wide applications in the field of network security.In this paper,we propose a hybrid Graph Convolutional Network(GCN)⁃GraphSAGE model for Anomaly Traffic Detection,namely HGS⁃ATD,which aims to improve the accuracy of anomaly traffic detection by leveraging edge feature learning to better capture the relationships between network entities.We validate the HGS⁃ATD model on four publicly available datasets,including NF⁃UNSW⁃NB15⁃v2.The experimental results show that the enhanced hybrid model is 5.71%to 10.25%higher than the baseline model in terms of accuracy,and the F1⁃score is 5.53%to 11.63%higher than the baseline model,proving that the model can effectively distinguish normal traffic from attack traffic and accurately classify various types of attacks. 展开更多
关键词 anomaly traffic detection graph neural network deep learning graph convolutional network
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A Recursive Method to Encryption-Decryption-Based Distributed Set-Membership Filtering for Time-Varying Saturated Systems Over Sensor Networks
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作者 Jun Hu Jiaxing Li +2 位作者 Chaoqing Jia Xiaojian Yi Hongjian Liu 《IEEE/CAA Journal of Automatica Sinica》 2025年第5期1047-1049,共3页
Dear Editor,This letter deals with the distributed recursive set-membership filtering(DRSMF)issue for state-saturated systems under encryption-decryption mechanism.To guarantee the data security,the encryption-decrypt... Dear Editor,This letter deals with the distributed recursive set-membership filtering(DRSMF)issue for state-saturated systems under encryption-decryption mechanism.To guarantee the data security,the encryption-decryption mechanism is considered in the signal transmission process.Specifically,a novel DRSMF scheme is developed such that,for both state saturation and encryption-decryption mechanism,the filtering error(FE)is limited to the ellipsoid domain.Then,the filtering error constraint matrix(FECM)is computed and a desirable filter gain is derived by minimizing the FECM.Besides,the bound-edness evaluation of the FECM is provided. 展开更多
关键词 time varying saturated systems signal transmission processspecificallya encryption decryption mechanism sensor networks recursive method distributed set membership filtering
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Conditional Generative Adversarial Network-Based Travel Route Recommendation
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作者 Sunbin Shin Luong Vuong Nguyen +3 位作者 Grzegorz J.Nalepa Paulo Novais Xuan Hau Pham Jason J.Jung 《Computers, Materials & Continua》 2026年第1期1178-1217,共40页
Recommending personalized travel routes from sparse,implicit feedback poses a significant challenge,as conventional systems often struggle with information overload and fail to capture the complex,sequential nature of... Recommending personalized travel routes from sparse,implicit feedback poses a significant challenge,as conventional systems often struggle with information overload and fail to capture the complex,sequential nature of user preferences.To address this,we propose a Conditional Generative Adversarial Network(CGAN)that generates diverse and highly relevant itineraries.Our approach begins by constructing a conditional vector that encapsulates a user’s profile.This vector uniquely fuses embeddings from a Heterogeneous Information Network(HIN)to model complex user-place-route relationships,a Recurrent Neural Network(RNN)to capture sequential path dynamics,and Neural Collaborative Filtering(NCF)to incorporate collaborative signals from the wider user base.This comprehensive condition,further enhanced with features representing user interaction confidence and uncertainty,steers a CGAN stabilized by spectral normalization to generate high-fidelity latent route representations,effectively mitigating the data sparsity problem.Recommendations are then formulated using an Anchor-and-Expand algorithm,which selects relevant starting Points of Interest(POI)based on user history,then expands routes through latent similarity matching and geographic coherence optimization,culminating in Traveling Salesman Problem(TSP)-based route optimization for practical travel distances.Experiments on a real-world check-in dataset validate our model’s unique generative capability,achieving F1 scores ranging from 0.163 to 0.305,and near-zero pairs−F1 scores between 0.002 and 0.022.These results confirm the model’s success in generating novel travel routes by recommending new locations and sequences rather than replicating users’past itineraries.This work provides a robust solution for personalized travel planning,capable of generating novel and compelling routes for both new and existing users by learning from collective travel intelligence. 展开更多
关键词 Travel route recommendation conditional generative adversarial network heterogeneous information network anchor-and-expand algorithm
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Artificial Intelligence (AI)-Enabled Unmanned Aerial Vehicle (UAV) Systems for Optimizing User Connectivity in Sixth-Generation (6G) Ubiquitous Networks
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作者 Zeeshan Ali Haider Inam Ullah +2 位作者 Ahmad Abu Shareha Rashid Nasimov Sufyan Ali Memon 《Computers, Materials & Continua》 2026年第1期534-549,共16页
The advent of sixth-generation(6G)networks introduces unprecedented challenges in achieving seamless connectivity,ultra-low latency,and efficient resource management in highly dynamic environments.Although fifth-gener... The advent of sixth-generation(6G)networks introduces unprecedented challenges in achieving seamless connectivity,ultra-low latency,and efficient resource management in highly dynamic environments.Although fifth-generation(5G)networks transformed mobile broadband and machine-type communications at massive scales,their properties of scaling,interference management,and latency remain a limitation in dense high mobility settings.To overcome these limitations,artificial intelligence(AI)and unmanned aerial vehicles(UAVs)have emerged as potential solutions to develop versatile,dynamic,and energy-efficient communication systems.The study proposes an AI-based UAV architecture that utilizes cooperative reinforcement learning(CoRL)to manage an autonomous network.The UAVs collaborate by sharing local observations and real-time state exchanges to optimize user connectivity,movement directions,allocate power,and resource distribution.Unlike conventional centralized or autonomous methods,CoRL involves joint state sharing and conflict-sensitive reward shaping,which ensures fair coverage,less interference,and enhanced adaptability in a dynamic urban environment.Simulations conducted in smart city scenarios with 10 UAVs and 50 ground users demonstrate that the proposed CoRL-based UAV system increases user coverage by up to 10%,achieves convergence 40%faster,and reduces latency and energy consumption by 30%compared with centralized and decentralized baselines.Furthermore,the distributed nature of the algorithm ensures scalability and flexibility,making it well-suited for future large-scale 6G deployments.The results highlighted that AI-enabled UAV systems enhance connectivity,support ultra-reliable low-latency communications(URLLC),and improve 6G network efficiency.Future work will extend the framework with adaptive modulation,beamforming-aware positioning,and real-world testbed deployment. 展开更多
关键词 6G networks UAV-based communication cooperative reinforcement learning network optimization user connectivity energy efficiency
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Analysis of DC Aging Characteristics of Stable ZnO Varistors Based on Voronoi Network and Finite Element Simulation Model
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作者 ZHANG Ping LU Mingtai +1 位作者 LU Tiantian YUE Yinghu 《材料导报》 北大核心 2026年第2期20-28,共9页
In modern ZnO varistors,traditional aging mechanisms based on increased power consumption are no longer relevant due to reduced power consumption during DC aging.Prolonged exposure to both AC and DC voltages results i... In modern ZnO varistors,traditional aging mechanisms based on increased power consumption are no longer relevant due to reduced power consumption during DC aging.Prolonged exposure to both AC and DC voltages results in increased leakage current,decreased breakdown voltage,and lower nonlinearity,ultimately compromising their protective performance.To investigate the evolution in electrical properties during DC aging,this work developed a finite element model based on Voronoi networks and conducted accelerated aging tests on commercial varistors.Throughout the aging process,current-voltage characteristics and Schottky barrier parameters were measured and analyzed.The results indicate that when subjected to constant voltage,current flows through regions with larger grain sizes,forming discharge channels.As aging progresses,the current focus increases on these channels,leading to a decline in the varistor’s overall performance.Furthermore,analysis of the Schottky barrier parameters shows that the changes in electrical performance during aging are non-monotonic.These findings offer theoretical support for understanding the aging mechanisms and condition assessment of modern stable ZnO varistors. 展开更多
关键词 ZnO varistors Voronoi network DC aging finite element method(FEM) current distribution double Schottky barrier theory
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Blockchain-Enabled Trusted Virtual Network Embedding in Intelligent Cyber-Physical Systems
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作者 Zhu Hailong Huang Tao +2 位作者 Zhang Yi Chen Ning Zhang Peiying 《China Communications》 2026年第1期175-188,共14页
With the rapid development of intelligent cyber-physical systems(ICPS),diverse services with varying Quality of Service(QoS)requirements have brought great challenges to traditional network resource allocation.Further... With the rapid development of intelligent cyber-physical systems(ICPS),diverse services with varying Quality of Service(QoS)requirements have brought great challenges to traditional network resource allocation.Furthermore,given the open environment and a multitude of devices,enhancing the security of ICPS is an urgent concern.To address these issues,this paper proposes a novel trusted virtual network embedding(T-VNE)approach for ICPS based combining blockchain and edge computing technologies.Additionally,the proposed algorithm leverages a deep reinforcement learning(DRL)model to optimize decision-making processes.It employs the policygradient-based agent to compute candidate embedding nodes and utilizes a breadth-first search(BFS)algorithm to determine the optimal embedding paths.Finally,through simulation experiments,the efficacy of the proposed method was validated,demonstrating outstanding performance in terms of security,revenue generation,and virtual network request(VNR)acceptance rate. 展开更多
关键词 blockchain cyber-physical system trusted embedding virtual network
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Artificial Neural Network Model for Thermal Conductivity Estimation of Metal Oxide Water-Based Nanofluids
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作者 Nikhil S.Mane Sheetal Kumar Dewangan +3 位作者 Sayantan Mukherjee Pradnyavati Mane Deepak Kumar Singh Ravindra Singh Saluja 《Computers, Materials & Continua》 2026年第1期316-331,共16页
The thermal conductivity of nanofluids is an important property that influences the heat transfer capabilities of nanofluids.Researchers rely on experimental investigations to explore nanofluid properties,as it is a n... The thermal conductivity of nanofluids is an important property that influences the heat transfer capabilities of nanofluids.Researchers rely on experimental investigations to explore nanofluid properties,as it is a necessary step before their practical application.As these investigations are time and resource-consuming undertakings,an effective prediction model can significantly improve the efficiency of research operations.In this work,an Artificial Neural Network(ANN)model is developed to predict the thermal conductivity of metal oxide water-based nanofluid.For this,a comprehensive set of 691 data points was collected from the literature.This dataset is split into training(70%),validation(15%),and testing(15%)and used to train the ANN model.The developed model is a backpropagation artificial neural network with a 4–12–1 architecture.The performance of the developed model shows high accuracy with R values above 0.90 and rapid convergence.It shows that the developed ANN model accurately predicts the thermal conductivity of nanofluids. 展开更多
关键词 Artificial neural networks nanofluids thermal conductivity PREDICTION
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Network perspective on rumination and non-suicidal self-injury among adolescents with depressive disorders
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作者 Fang-Fang Zhang Rui Guo +3 位作者 Si-Lan Chen Wei Yang Xing-Li Liang Ming-Fang Ma 《World Journal of Psychiatry》 2026年第1期346-355,共10页
BACKGROUND Non-suicidal self-injury(NSSI)is common among adolescents with depressive disorders and poses a major public health challenge.Rumination,a key cognitive feature of depression,includes different subtypes tha... BACKGROUND Non-suicidal self-injury(NSSI)is common among adolescents with depressive disorders and poses a major public health challenge.Rumination,a key cognitive feature of depression,includes different subtypes that may relate to NSSI through distinct psychological mechanisms.However,how these subtypes interact with specific NSSI behaviors remains unclear.AIM To examine associations between rumination subtypes and specific NSSI behaviors in adolescents.METHODS We conducted a cross-sectional study with 305 hospitalized adolescents diagnosed with depressive disorders.The subjects ranged from 12-18 years in age.Rumi-nation subtypes were assessed using the Ruminative Response Scale,and 12 NSSI behaviors were evaluated using a validated questionnaire.Network analysis was applied to explore symptom-level associations and identify central symptoms.RESULTS The network analysis revealed close connections between rumination subtypes and NSSI behaviors.Brooding was linked to behaviors such as hitting objects and burning.Scratching emerged as the most influential NSSI symptom.Symptomfocused rumination served as a key bridge connecting rumination and NSSI.CONCLUSION Symptom-focused rumination and scratching were identified as potential intervention targets.These findings highlight the psychological significance of specific cognitive-behavioral links in adolescent depression and suggest directions for tailored prevention and treatment.However,the cross-sectional,single-site design limits causal inference and generalizability.Future longitudinal and multi-center studies are needed to confirm causal pathways and verify the generalizability of the findings to broader adolescent populations. 展开更多
关键词 Depressive disorders Adolescents network analysis RUMINATION Non-suicidal self-injury
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Recurrent MAPPO for Joint UAV Trajectory and Traffic Offloading in Space-Air-Ground Integrated Networks
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作者 Zheyuan Jia Fenglin Jin +1 位作者 Jun Xie Yuan He 《Computers, Materials & Continua》 2026年第1期447-461,共15页
This paper investigates the traffic offloading optimization challenge in Space-Air-Ground Integrated Networks(SAGIN)through a novel Recursive Multi-Agent Proximal Policy Optimization(RMAPPO)algorithm.The exponential g... This paper investigates the traffic offloading optimization challenge in Space-Air-Ground Integrated Networks(SAGIN)through a novel Recursive Multi-Agent Proximal Policy Optimization(RMAPPO)algorithm.The exponential growth of mobile devices and data traffic has substantially increased network congestion,particularly in urban areas and regions with limited terrestrial infrastructure.Our approach jointly optimizes unmanned aerial vehicle(UAV)trajectories and satellite-assisted offloading strategies to simultaneously maximize data throughput,minimize energy consumption,and maintain equitable resource distribution.The proposed RMAPPO framework incorporates recurrent neural networks(RNNs)to model temporal dependencies in UAV mobility patterns and utilizes a decentralized multi-agent reinforcement learning architecture to reduce communication overhead while improving system robustness.The proposed RMAPPO algorithm was evaluated through simulation experiments,with the results indicating that it significantly enhances the cumulative traffic offloading rate of nodes and reduces the energy consumption of UAVs. 展开更多
关键词 Space-air-ground integrated networks UAV traffic offloading reinforcement learning
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Research Progress and Network Pharmacological Analysis of Single Herb Improvement of Functional Dyspepsia by Jineijin Shanzha(Galli Gigerii Endothelium Corneum and Crataegi Fructus)Traditional Chinese Medicine Patch
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作者 Yingbing HE Tianbao ZHANG Quan SHI 《Medicinal Plant》 2026年第1期10-19,共10页
[Objectives]To investigate the efficacy and potential mechanism of the topical preparation Jineijin-Shanzha Patch(composed of Galli Gigerii Endothelium Corneum and Crataegi Fructus)in improving functional dyspepsia(FD... [Objectives]To investigate the efficacy and potential mechanism of the topical preparation Jineijin-Shanzha Patch(composed of Galli Gigerii Endothelium Corneum and Crataegi Fructus)in improving functional dyspepsia(FD)based on network pharmacology.[Methods]Firstly,we reviewed the existing research progress on each constituent drug of the Jineijin Shanzha Patch for FD improvement.Following this,identified overlapping genes were utilized to construct both a"Drug-Active Component-FD Target"network and a Protein-Protein Interaction(PPI)network specific to the patch.In addition,Gene Ontology(GO)analysis was carried out.[Results]We identified that the 13 herbs in the Jineijin Shanzha Patch are mainly used for food stagnation,qi stagnation,and spleen deficiency.Screening revealed 43 active patch components,1414 FD-related targets,and 284 shared targets between them.The PPI network analysis further identified the top 10 core targets from these shared targets.From the"Drug-Active Component-FD Target"network,we identified the core elements.These included the herbal components Vignae Semen(from Liushenqu),Crataegi Fructus,and Pseudostellariae Radix;the active components quercetin,genistein,and apigenin;and the key targets CASP3,BCL2,and CASP9.GO analysis of the 284 overlapping targets indicated that the Jineijin Shanzha Patch may exert its therapeutic effects via regulation of biological processes such as the response to lipopolysaccharide,response to bacterium-derived molecules,and regulation of the apoptotic signaling pathway.[Conclusions]The main active components of the Jineijin Shanzha Patch(quercetin,genistein,and apigenin)may improve FD by modulating signaling pathways such as the response to lipopolysaccharide,response to bacterium-derived molecules,and regulation of the apoptotic signaling pathway,thereby acting on key targets including CASP3,BCL2,and CASP9. 展开更多
关键词 Medicinal plant Functional dyspepsia Action mechanism network pharmacology
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Defect Identification Method of Power Grid Secondary Equipment Based on Coordination of Knowledge Graph and Bayesian Network Fusion
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作者 Jun Xiong Peng Yang +1 位作者 Bohan Chen Zeming Chen 《Energy Engineering》 2026年第1期296-313,共18页
The reliable operation of power grid secondary equipment is an important guarantee for the safety and stability of the power system.However,various defects could be produced in the secondary equipment during longtermo... The reliable operation of power grid secondary equipment is an important guarantee for the safety and stability of the power system.However,various defects could be produced in the secondary equipment during longtermoperation.The complex relationship between the defect phenomenon andmulti-layer causes and the probabilistic influence of secondary equipment cannot be described through knowledge extraction and fusion technology by existing methods,which limits the real-time and accuracy of defect identification.Therefore,a defect recognition method based on the Bayesian network and knowledge graph fusion is proposed.The defect data of secondary equipment is transformed into the structured knowledge graph through knowledge extraction and fusion technology.The knowledge graph of power grid secondary equipment is mapped to the Bayesian network framework,combined with historical defect data,and introduced Noisy-OR nodes.The prior and conditional probabilities of the Bayesian network are then reasonably assigned to build a model that reflects the probability dependence between defect phenomena and potential causes in power grid secondary equipment.Defect identification of power grid secondary equipment is achieved by defect subgraph search based on the knowledge graph,and defect inference based on the Bayesian network.Practical application cases prove this method’s effectiveness in identifying secondary equipment defect causes,improving identification accuracy and efficiency. 展开更多
关键词 Knowledge graph Bayesian network secondary equipment defect identification
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Investigating the potential mechanisms of Wenqing Yin against atopic dermatitis based on network pharmacology,experimental pharmacology,and molecular docking
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作者 Yi Wang Zhen Liu +3 位作者 Si-Man Li Lin Lin Wei Dai Meng-Yue Ren 《Traditional Medicine Research》 2026年第2期1-11,共11页
Background:Wenqing Yin(WQY)is a classic prescription used to treat skin diseases like atopic dermatitis(AD)in China,and the aim of this study is to investigate the therapeutic effects and molecular mechanisms of WQY o... Background:Wenqing Yin(WQY)is a classic prescription used to treat skin diseases like atopic dermatitis(AD)in China,and the aim of this study is to investigate the therapeutic effects and molecular mechanisms of WQY on AD.Methods:The DNFB-induced mouse models of AD were established to investigate the therapeutic effects of WQY on AD.The symptoms of AD in the ears and backs of the mice were assessed,while inflammatory factors in the ear were quantified using quantitative real-time-polymerase chain reaction(qRT-PCR),and the percentages of CD4^(+)and CD8^(+)cells in the spleen were analyzed through flow cytometry.The compounds in WQY were identified using ultra-performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)analysis and the key targets and pathways of WQY to treat AD were predicted by network pharmacology.Subsequently,the key genes were tested and verified by qRT-PCR,and the potential active components and target proteins were verified by molecular docking.Results:WQY relieved the AD symptoms and histopathological injuries in the ear and back skin of mice with AD.Meanwhile,WQY significantly reduced the levels of inflammatory factors IL-6 and IL-1βin ear tissue,as well as the ratio of CD4^(+)/CD8^(+)cells in spleen.Additionally,a total of 142 compounds were identified from the water extract of WQY by UPLC-Orbitrap-MS/MS.39 key targets related to AD were screened out by network pharmacology methods.The KEGG analysis indicated that the effects of WQY were primarily mediated through pathways associated with Toll-like receptor signaling and T cell receptor signaling.Moreover,the results of qRT-PCR demonstrated that WQY significantly reduced the mRNA expressions of IL-4,IL-10,GATA3 and FOXP3,and molecular docking simulation verified that the active components of WQY had excellent binding abilities with IL-4,IL-10,GATA3 and FOXP3 proteins.Conclusion:The present study demonstrated that WQY effectively relieved AD symptoms in mice,decreased the inflammatory factors levels,regulated the balance of CD4^(+)and CD8^(+)cells,and the mechanism may be associated with the suppression of Th2 and Treg cell immune responses. 展开更多
关键词 Wenqing Yin atopic dermatitis mouse model UPLC-Orbitrap-MS/MS network pharmacology
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An artificial synapse capable of regulating signal transmission speed in a neuromorphic network
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作者 Jingru Sun Xiaosong Li +2 位作者 Yichuang Sun Zining Xiong Jiqi He 《Chinese Physics B》 2026年第1期66-77,共12页
The regulation of signal transmission speed is one of the most important capabilities of the biological nervous system.This study explores the mechanisms and methods for regulating signal transmission speed among nonm... The regulation of signal transmission speed is one of the most important capabilities of the biological nervous system.This study explores the mechanisms and methods for regulating signal transmission speed among nonmyelinated neurons within the same brain region,starting from spike-timing-dependent plasticity(STDP)of synapses.Building upon the Hodgkin-Huxley model,the dynamic behavior of synapses is incorporated,and the adaptive growth neuron(AGN)model is proposed.Artificial synaptic structures and neuronal physical nodes are also designed.The artificial synaptic structure exhibits unidirectionality,memory capacity,and STDP,enabling it to connect neuronal physical nodes through branching and merging structures.Furthermore,the artificial synapse can adjust signal transmission speed,regulate functional competition between different regions of the neuromorphic network,and promote information interaction.The findings of this study endow neuromorphic networks with the ability to regulate signal transmission speed over the long term,providing new insights into the development of neuromorphic networks. 展开更多
关键词 artificial synapse neuromorphic networks Hodgkin-Huxley model neuron circuit MEMRISTOR NEURODYNAMICS
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