期刊文献+
共找到224,837篇文章
< 1 2 250 >
每页显示 20 50 100
Accurate closed-form flutter eigensolutions of three-dimensional composite laminates with shear deformation
1
作者 Dezhuang PAN Yufeng XING 《Chinese Journal of Aeronautics》 2026年第1期230-246,共17页
According to the Mindlin plate theory and the first-order piston theory,this work obtains accurate closed-form eigensolutions for the flutter problem of three-dimensional(3D)rectangular laminated panels.The governing ... According to the Mindlin plate theory and the first-order piston theory,this work obtains accurate closed-form eigensolutions for the flutter problem of three-dimensional(3D)rectangular laminated panels.The governing differential equations are derived by the Hamilton's variational principle,and then solved by the iterative Separation-of-Variable(i SOV)method,which are applicable to arbitrary combinations of homogeneous Boundary Conditions(BCs).However,only the simply-support,clamped and cantilever panels are considered in this work for the sake of clarity.With the closed-form eigensolutions,the flutter frequency,flutter mode and flutter boundary are presented,and the effect of shear deformation and aerodynamic damping on flutter frequencies is investigated.Besides,the relation between panel energy and the work of aerodynamic load is discussed.The numerical comparisons reveal the following.(A)The flutter eigenvalues obtained by the present method are accurate,validated by the Finite Element Method(FEM)and the Galerkin method.(B)When the span-chord ratio is larger than 3,simplifying a 3D panel to 2D(two-dimensional)panel is reasonable and the relative differences of the flutter points predicted by the two models are less than one percent.(C)The reciprocal relationship between the mechanical energy of the panel and the work done by aerodynamic load is verified by using the present flutter eigenvalues and modes,further indicating the high accuracy of the present solutions.(D)The coupling of shear deformation and aerodynamic damping prevents frequency coalescing. 展开更多
关键词 Closed-form eigensolutions The first-order piston theory The Mindlin plate theory three-dimensional panel flutter Separation-of-variable method
原文传递
Digital reconstruction of three-dimensional contours and its application to microstructural evaluation of postblast rock fissure surfaces
2
作者 Yanbing Wang Zhaoyang Wang +1 位作者 Dairui Fu Mingwei Gang 《Deep Underground Science and Engineering》 2025年第2期316-328,共13页
Fracture surface contour study is one of the important requirements for characterization and evaluation of the microstructure of rocks.Based on the improved cube covering method and the 3D contour digital reconstructi... Fracture surface contour study is one of the important requirements for characterization and evaluation of the microstructure of rocks.Based on the improved cube covering method and the 3D contour digital reconstruction model,this study proposes a quantitative microstructure characterization method combining the roughness evaluation index and the 3D fractal dimension to study the change rule of the fracture surface morphology after blasting.This method was applied and validated in the study of the fracture microstructure of the rock after blasting.The results show that the fracture morphology characteristics of the 3D contour digital reconstruction model have good correlation with the changes of the blasting action.The undulation rate of the three-dimensional surface profile of the rock is more prone to dramatic rise and dramatic fall morphology.In terms of tilting trend,the tilting direction also shows gradual disorder,with the tilting angle increasing correspondingly.All the roughness evaluation indexes of the rock fissure surface after blasting show a linear and gradually increasing trend as the distance to the bursting center increases;the difference between the two-dimensional roughness evaluation indexes and the three-dimensional ones of the same micro-area rock samples also becomes increasingly larger,among which the three-dimensional fissure roughness coefficient JRC and the surface roughness ratio Rs display better correlation.Compared with the linear fitting formula of the power function relationship,the three-dimensional fractal dimension of the postblast fissure surface is fitted with the values of JRC and Rs,which renders higher correlation coefficients,and the degree of linear fitting of JRC to the three-dimensional fractal dimension is higher.The fractal characteristics of the blast-affected region form a unity with the three-dimensional roughness evaluation of the fissure surface. 展开更多
关键词 cube covering method evaluation of damage characterization fractal dimension roughness three-dimensional contour scanning
原文传递
Artificial intelligence-aided semi-automatic joint trace detection from textured three-dimensional models of rock mass 被引量:1
3
作者 Seyedahmad Mehrishal Jineon Kim +1 位作者 Yulong Shao Jae Joon Song 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第4期1973-1985,共13页
It is of great importance to obtain precise trace data,as traces are frequently the sole visible and measurable parameter in most outcrops.The manual recognition and detection of traces on high-resolution three-dimens... It is of great importance to obtain precise trace data,as traces are frequently the sole visible and measurable parameter in most outcrops.The manual recognition and detection of traces on high-resolution three-dimensional(3D)models are relatively straightforward but time-consuming.One potential solution to enhance this process is to use machine learning algorithms to detect the 3D traces.In this study,a unique pixel-wise texture mapper algorithm generates a dense point cloud representation of an outcrop with the precise resolution of the original textured 3D model.A virtual digital image rendering was then employed to capture virtual images of selected regions.This technique helps to overcome limitations caused by the surface morphology of the rock mass,such as restricted access,lighting conditions,and shading effects.After AI-powered trace detection on two-dimensional(2D)images,a 3D data structuring technique was applied to the selected trace pixels.In the 3D data structuring,the trace data were structured through 2D thinning,3D reprojection,clustering,segmentation,and segment linking.Finally,the linked segments were exported as 3D polylines,with each polyline in the output corresponding to a trace.The efficacy of the proposed method was assessed using a 3D model of a real-world case study,which was used to compare the results of artificial intelligence(AI)-aided and human intelligence trace detection.Rosette diagrams,which visualize the distribution of trace orientations,confirmed the high similarity between the automatically and manually generated trace maps.In conclusion,the proposed semi-automatic method was easy to use,fast,and accurate in detecting the dominant jointing system of the rock mass. 展开更多
关键词 Automatic trace detection digital joint mapping Rock discontinuities characterization three-dimensional(3D)trace network
在线阅读 下载PDF
Three-dimensional visualization interactive system for digital twin workshop 被引量:8
4
作者 Zhang Qinglei Yang Zhiwei +2 位作者 Duan Jianguo Liu Zhen Qin Jiyun 《Journal of Southeast University(English Edition)》 EI CAS 2021年第2期137-152,共16页
To improve the human-physical-virtual coordination and integration of the digital twin workshop,3D visual monitoring and human-computer interaction of the digital twin workshop was studied.First,a novel 6D model of th... To improve the human-physical-virtual coordination and integration of the digital twin workshop,3D visual monitoring and human-computer interaction of the digital twin workshop was studied.First,a novel 6D model of the 3D visualization interactive system for digital twin workshops is proposed.As the traditional 5D digital twin model ignores the importance of human-computer interaction,a new dimension of the user terminal was added.A hierarchical real-time data-driven mapping model for the workshop production process is then proposed.Moreover,a real-time data acquisition method for the industrial Internet of things is proposed based on OPC UA(object linking and embedding for process control unified architecture).Based on the 6D model of the system,the process of creating a 3D visualization virtual environment based on virtual reality is introduced,in addition to a data-driven process based on the data management cloud platform.Finally,the 6D model of the system was confirmed using the blade rotor test workshop as the object,and a 3D visualization interactive system is developed.The results show that the system is more transparent,real-time,data-driven and more efficient,as well as promotes the coordination and integration of human-physical-virtual,which has practical significance for developing digital twin workshops. 展开更多
关键词 digital twin workshop three-dimensional visualization human-computer interaction data driven OPC UA(object linking and embedding for process control unified architecture)
在线阅读 下载PDF
Specimen aspect ratio and progressive field strain development of sandstone under uniaxial compression by three-dimensional digital image correlation 被引量:15
5
作者 H. Munoz A. Taheri 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2017年第4期599-610,共12页
The complete stress-strain characteristics of sandstone specimens were investigated in a series of quasistatic monotonic uniaxial compression tests.Strain patterns development during pre-and post-peak behaviours in sp... The complete stress-strain characteristics of sandstone specimens were investigated in a series of quasistatic monotonic uniaxial compression tests.Strain patterns development during pre-and post-peak behaviours in specimens with different aspect ratios was also examined.Peak stress,post-peak portion of stress-strain,brittleness,characteristics of progressive localisation and field strain patterns development were affected at different extents by specimen aspect ratio.Strain patterns of the rocks were obtained by applying three-dimensional(3D) digital image correlation(DIC) technique.Unlike conventional strain measurement using strain gauges attached to specimen,3D DIC allowed not only measuring large strains,but more importantly,mapping the development of field strain throughout the compression test,i.e.in pre-and post-peak regimes.Field strain development in the surface of rock specimen suggests that strain starts localising progressively and develops at a lower rate in pre-peak regime.However,in post-peak regime,strains increase at different rates as local deformations take place at different extents in the vicinity and outside the localised zone.The extent of localised strains together with the rate of strain localisation is associated with the increase in rate of strength degradation.Strain localisation and local inelastic unloading outside the localised zone both feature post-peak regime. 展开更多
关键词 Uniaxial compression test Aspect ratio Strain patterns digital image correlation(DIC)
在线阅读 下载PDF
Optical encryption of multiple three-dimensional objects based on multiple interferences and single-pixel digital holography 被引量:2
6
作者 Ying Wang Qi Liu +1 位作者 Jun Wang Qiong-Hua Wang 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第3期253-259,共7页
We present an optical encryption method of multiple three-dimensional objects based on multiple interferences and single-pixel digital holography. By modifying the Mach-Zehnder interferometer, the interference of the ... We present an optical encryption method of multiple three-dimensional objects based on multiple interferences and single-pixel digital holography. By modifying the Mach-Zehnder interferometer, the interference of the multiple objects beams and the one reference beam is used to simultaneously encrypt multiple objects into a ciphertext. During decryption, each three-dimensional object can be decrypted independently without having to decrypt other objects. Since the single- pixel digital holography based on compressive sensing theory is introduced, the encrypted data of this method is effectively reduced. In addition, recording fewer encrypted data can greatly reduce the bandwidth of network transmission. Moreover, the compressive sensing essentially serves as a secret key that makes an intruder attack invalid, which means that the system is more secure than the conventional encryption method. Simulation results demonstrate the feasibility of the proposed method and show that the system has good security performance. 展开更多
关键词 multiple three-dimensional objects encryption single-pixel digital holography phase-shifting in- terference compressive sensing
原文传递
Three-dimensional line-of-sight-angle-constrained leader-following cooperative interception guidance law with prespecified impact time 被引量:3
7
作者 Hao YOU Xinlong CHANG Jiufen ZHAO 《Chinese Journal of Aeronautics》 2025年第1期491-506,共16页
To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D lea... To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D leader-following cooperative interception guidance law.First,in the LOS direction of the leader,an impact time-controlled guidance law is derived based on the fixed-time stability theory,which enables the leader to complete the interception task at a prespecified impact time.Next,in the LOS direction of the followers,by introducing a time consensus tracking error function,a fixed-time consensus tracking guidance law is investigated to guarantee the consensus tracking convergence of the time-to-go.Then,in the direction normal to the LOS,by combining the designed global integral sliding mode surface and the second-order Sliding Mode Control(SMC)theory,an innovative 3D LOS-angle-constrained interception guidance law is developed,which eliminates the reaching phase in the traditional sliding mode guidance laws and effectively saves energy consumption.Moreover,it effectively suppresses the chattering phenomenon while avoiding the singularity issue,and compensates for unknown interference caused by target maneuvering online,making it convenient for practical engineering applications.Finally,theoretical proof analysis and multiple sets of numerical simulation results verify the effectiveness,superiority,and robustness of the investigated guidance law. 展开更多
关键词 three-dimensional cooperative interception Leader-following missiles Prespecified impact time LOS-angle-constrained Fixed-time stability Global integral sliding mode
原文传递
A combination of digital design and three-dimensional printing to assist treatment of thoracolumbar compression fractures using percutaneous kyphoplasty 被引量:2
8
作者 Hui Lu Daixiang Jiang +1 位作者 Qimei Wu Rong Liu 《Global Health Journal》 2021年第4期190-193,共4页
Objective:To evaluate the clinical efficacy of the preoperative digita1 design combined with three dimensional(3D)printing models to assist percutaneous kyphoplasty(PKP)treatment for thoracolumbar compression frac tur... Objective:To evaluate the clinical efficacy of the preoperative digita1 design combined with three dimensional(3D)printing models to assist percutaneous kyphoplasty(PKP)treatment for thoracolumbar compression frac tures.Methods:From January 2018 to August 2020,we obtained data of 99 patients diagnosed thoracolumbar compression fractures.These patients were divided into control group(n=50)underwent traditional PKP surgery,and observation group(n=49)underwent preoperative digital design combined with 3D printing model assisted PKP treatment.The clinical efficacy was evaluated with five parameters,including operation time,number of intraoperative radiographs,visual analogue scale(VAS)score,Cobb Angle change,and high compression rate of injured vertebrae.Results:There were statistically significant differences of operation time and number of intraoperative radio graphs between the two groups(P<0.05).For VAS score,Cobb Angle change and vertebral height compression rate,all of these three parameters were significantly improved when the patients accepted surgery teatment in two groups(P<0.05).However,there were no significant differences between control group and observation group for these three parameters either before or after surgery(P>0.05).Conclusions:Through the design of preoperative surgical guide plate and the application of 3D printing model to guide the operation,the precise design of preoperative surgical puncture site and puncture Angle of the injured vertebra was realized,the number of intraoperative radiographs was reduced,the operation time was shortened and the operation efficiency was improved. 展开更多
关键词 Percutaneous kyphoplasty Thoracolumbar compression fracture digital design three-dimensional(3D)printing
暂未订购
Global Mapping of Three-Dimensional Urban Structures Reveals Escalating Utilization in the Vertical Dimension and Pronounced Building Space Inequality 被引量:1
9
作者 Xiaoping Liu Xinxin Wu +6 位作者 Xuecao Li Xiaocong Xu Weilin Liao Limin Jiao Zhenzhong Zeng Guangzhao Chen Xia Li 《Engineering》 2025年第4期86-99,共14页
Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significan... Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significant gap in detailed and consistent data on 3D building space structures with global coverage due to the challenges inherent in the data collection and model calibration processes.In this study,we constructed a global urban structure(GUS-3D)dataset,including building volume,height,and footprint information,at a 500 m spatial resolution using extensive satellite observation products and numerous reference building samples.Our analysis indicated that the total volume of buildings worldwide in2015 exceeded 1×10^(12)m^(3).Over the 1985 to 2015 period,we observed a slight increase in the magnitude of 3D building volume growth(i.e.,it increased from 166.02 km3 during the 1985–2000 period to 175.08km3 during the 2000–2015 period),while the expansion magnitudes of the two-dimensional(2D)building footprint(22.51×10^(3) vs 13.29×10^(3)km^(2))and urban extent(157×10^(3) vs 133.8×10^(3)km^(2))notably decreased.This trend highlights the significant increase in intensive vertical utilization of urban land.Furthermore,we identified significant heterogeneity in building space provision and inequality across cities worldwide.This inequality is particularly pronounced in many populous Asian cities,which has been overlooked in previous studies on economic inequality.The GUS-3D dataset shows great potential to deepen our understanding of the urban environment and creates new horizons for numerous 3D urban studies. 展开更多
关键词 three-dimensional Global mapping Building volume Building height Building space inequality
在线阅读 下载PDF
Three-dimensional reconstruction under computed tomography and myopectineal orifice measurement under laparoscopy for quality control of inguinal hernia treatment 被引量:1
10
作者 Lei Zhang Jing Chen +7 位作者 Yu-Ying Zhang Lei Liu Han-Dan Wang Ya-Fei Zhang Jun Sheng Qiu-Shi Hu Ming-Liang Liu Yi-Lin Yuan 《World Journal of Gastrointestinal Endoscopy》 2025年第3期50-59,共10页
BACKGROUND Inguinal hernias are common after surgery.Tension-free repair is widely accepted as the main method for managing inguinal hernias.Adequate exposure,coverage,and repair of the myopectineal orifice(MPO)are ne... BACKGROUND Inguinal hernias are common after surgery.Tension-free repair is widely accepted as the main method for managing inguinal hernias.Adequate exposure,coverage,and repair of the myopectineal orifice(MPO)are necessary.However,due to differences in race and sex,people’s body shapes vary.According to European guidelines,the patch should measure 10 cm×15 cm.If any part of the MPO is dissected,injury to the nerves,vascular network,or organs may occur during surgery,thereby leading to inguinal discomfort,pain,and seroma formation after surgery.Therefore,accurate localization and measurement of the boundary of the MPO are crucial for selecting the optimal patch for inguinal hernia repair.AIM To compare the size of the MPO measured on three-dimensional multislice spiral computed tomography(CT)with that measured via laparoscopy and explore the relevant factors influencing the size of the MPO.METHODS Clinical data from 74 patients who underwent laparoscopic tension-free inguinal hernia repair at the General Surgery Department of the First Affiliated Hospital of Anhui University of Science and Technology between September 2022 and July 2024 were collected and analyzed retrospectively.Transabdominal preperitoneal was performed.Sixty-four males and 10 females,with an average age of 58.30±12.32 years,were included.The clinical data of the patients were collected.The boundary of the MPO was measured on three-dimensional CT images before surgery and then again during transabdominal preperitoneal.All the preoperative and intraoperative data were analyzed via paired t-tests.A t-test was used for comparisons of age,body mass index,and sex between the groups.In the comparative analysis,a P value less than 0.05 indicated a significant difference.RESULTS The boundaries of the MPO on 3-dimensional CT images measured 7.05±0.47 cm and 6.27±0.61 cm,and the area of the MPO was 19.54±3.33 cm^(2).The boundaries of the MPO during surgery were 7.18±0.51 cm and 6.17±0.40 cm.The errors were not statistically significant.However,the intraoperative BD(the width of the MPO,P=0.024,P<0.05)and preoperative AC(the length of the MPO,P=0.045,P<0.05)significantly differed according to sex.The AC and BD measurements before and during surgery were not significantly different according to age,body mass index,hernia side or hernia type(P>0.05).CONCLUSION The application of this technology can aid in determining the most appropriate dissection range and patch size. 展开更多
关键词 HERNIA INGUINAL Myopectineal orifice three-dimensional reconstruction Computed tomography Inguinal hernia
暂未订购
From digits towards digitization:the past,present,and future of traditional Chinese medicine 被引量:2
11
作者 Qi WANG 《Digital Chinese Medicine》 2025年第1期4-19,共16页
Digitization is the inevitable path for the natural development of traditional Chinese medicine(TCM)in the context of the Fourth Industrial Revolution.The goal of TCM digitization is to generate intelligence from numb... Digitization is the inevitable path for the natural development of traditional Chinese medicine(TCM)in the context of the Fourth Industrial Revolution.The goal of TCM digitization is to generate intelligence from numbers.Originating from the reasoning paradigm of Xiangshu(象数,image-number)or phenotype-numerology thinking,TCM came with a deep correlation of clinical observations with digits and laid a strong theoretical basis for digitization.The digitization of TCM should start from the clinical aspect,solve the problem of electronic medical records,achieve standardization and informatization,and on this basis,form a TCM knowledge base through knowledge-building.This process depends on the combined efforts of multiple disciplines such as medicine,mathematics,and engineering to achieve the digitization and intelligent transformation of TCM.This era calls for TCM to break down barriers,embrace opportunities,and move towards digitization.However,during the transformation,it should maintain its essence,avoid simplistic conversions,be guided by scientific value,leverage cutting-edge technologies,and enhance the depth and breadth of the interpretation of TCM connotations.The digitization of TCM will also improve its service capabilities,create an innovative digitally-intelligent TCM service platform,and contribute to the development of“Healthy China”initiatives with wisdom and solutions. 展开更多
关键词 Traditional Chinese medicine(TCM) digitization Modernization of TCM Interdisciplinary integration
暂未订购
Three-Dimensional TIN Algorithm for Digital Terrain Modeling 被引量:7
12
作者 ZHU Qing ZHANG Yeting LI Fengchun 《Geo-Spatial Information Science》 2008年第2期79-85,共7页
The problem of taking an unorganized point cloud in 3D space and fitting a polyhedral surface to those points is both important and difficult. Aiming at increasing applications of full three dimensional digital terrai... The problem of taking an unorganized point cloud in 3D space and fitting a polyhedral surface to those points is both important and difficult. Aiming at increasing applications of full three dimensional digital terrain surface modeling, a new algorithm for the automatic generation of three dimensional triangulated irregular network from a point cloud is pro- posed. Based on the local topological consistency test, a combined algorithm of constrained 3D Delaunay triangulation and region-growing is extended to ensure topologically correct reconstruction. This paper also introduced an efficient neighbor- ing triangle location method by making full use of the surface normal information. Experimental results prove that this algo- rithm can efficiently obtain the most reasonable reconstructed mesh surface with arbitrary topology, wherein the automati- cally reconstructed surface has only small topological difference from the true surface. This algorithm has potential applica- tions to virtual environments, computer vision, and so on. 展开更多
关键词 three dimensional triangulated irregular network digital terrain surface modeling Delaunay triangulation
在线阅读 下载PDF
Dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions 被引量:1
13
作者 Chentong GAO Huiyu SUN +1 位作者 Jianping GU W.M.HUANG 《Applied Mathematics and Mechanics(English Edition)》 2025年第1期123-138,共16页
Currently,there are a limited number of dynamic models available for braided composite plates with large overall motions,despite the incorporation of three-dimensional(3D)braided composites into rotating blade compone... Currently,there are a limited number of dynamic models available for braided composite plates with large overall motions,despite the incorporation of three-dimensional(3D)braided composites into rotating blade components.In this paper,a dynamic model of 3D 4-directional braided composite thin plates considering braiding directions is established.Based on Kirchhoff's plate assumptions,the displacement variables of the plate are expressed.By incorporating the braiding directions into the constitutive equation of the braided composites,the dynamic model of the plate considering braiding directions is obtained.The effects of the speeds,braiding directions,and braided angles on the responses of the plate with fixed-axis rotation and translational motion,respectively,are investigated.This paper presents a dynamic theory for calculating the deformation of 3D braided composite structures undergoing both translational and rotational motions.It also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications. 展开更多
关键词 three-dimensional(3D)braided composite braiding direction composite thin plate large overall motion dynamic model
在线阅读 下载PDF
Three-dimensional models:from cell culture to Patient-Derived Organoid and its application to future liposarcoma research
14
作者 SAYUMI TAHARA SYDNEY RENTSCH +4 位作者 FERNANDA COSTAS CASAL DE FARIA PATRICIA SARCHET ROMA KARNA FEDERICA CALORE RAPHAEL E.POLLOCK 《Oncology Research》 SCIE 2025年第1期1-13,共13页
Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma ... Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma pathobiology.Conventional cell culture-based research(2D cell culture)is still playing a pivotal role,while several shortcomings have been recently under discussion.In vivo,mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell culture.However,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)characteristics.Therefore,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and in vivo animal models and fill in the gap between them.Given the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor Organoids(PDOs),represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy development.In this review,we first provide a general overview of 3D cell cultures compared to 2D cell cultures.We then focus on one of the recent 3D cell culture applications,Patient-Derived Organoids(PDOs),summarizing and discussing several PDO methodologies.Finally,we discuss the current and future applications of PDOs to sarcoma,particularly in the field of liposarcoma. 展开更多
关键词 Cell culture LIPOSARCOMA Patient-Derived Organoid(PDO) SPHEROID three-dimensional(3D)cell culture
暂未订购
Three-dimensional(3D)printing-assisted freeze-casting of processed pyritum-dopedβ-tricalcium phosphate biomimetic scaffold with angiogenesis and bone regeneration capability 被引量:1
15
作者 Chenxu WEI Zongan LI +9 位作者 Xiaoyun LIANG Yuwei ZHAO Xingyu ZHU Haibing HUA Guobao CHEN Kunming QIN Zhipeng CHEN Changcan SHI Feng ZHANG Weidong LI 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 2025年第9期863-880,共18页
Bone repair remains an important target in tissue engineering,making the development of bioactive scaffolds for effective bone defect repair a critical objective.In this study,β-tricalcium phosphate(β-TCP)scaffolds ... Bone repair remains an important target in tissue engineering,making the development of bioactive scaffolds for effective bone defect repair a critical objective.In this study,β-tricalcium phosphate(β-TCP)scaffolds incorporated with processed pyritum decoction(PPD)were fabricated using three-dimensional(3D)printing-assisted freeze-casting.The produced composite scaffolds were evaluated for their mechanical strength,physicochemical properties,biocompatibility,in vitro proangiogenic activity,and in vivo efficacy in repairing rabbit femoral defects.They not only demonstrated excellent physicochemical properties,enhanced mechanical strength,and good biosafety but also significantly promoted the proliferation,migration,and aggregation of pro-angiogenic human umbilical vein endothelial cells(HUVECs).In vivo studies revealed that all scaffold groups facilitated osteogenesis at the bone defect site,with theβ-TCP scaffolds loaded with PPD markedly enhancing the expression of neurogenic locus Notch homolog protein 1(Notch1),vascular endothelial growth factor(VEGF),bone morphogenetic protein-2(BMP-2),and osteopontin(OPN).Overall,the scaffolds developed in this study exhibited strong angiogenic and osteogenic capabilities both in vitro and in vivo.The incorporation of PPD notably promoted the angiogenic-osteogenic coupling,thereby accelerating bone repair,which suggests that PPD is a promising material for bone repair and that the PPD/β-TCP scaffolds hold great potential as a bone graft alternative. 展开更多
关键词 Bone defect Processed pyritum three-dimensional(3D)printing-assisted freeze-casting ANGIOGENESIS Bone regeneration VEGF-Notch1-BMP-2-OPN coupling
原文传递
Real-time model updating and prediction of three-dimensional timevarying consolidation settlement using machine learning
16
作者 Huaming Tian Yu Wang Danni Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第9期5954-5969,共16页
The development of digital twins for geotechnical structures necessitates the real-time updates of threedimensional(3D)virtual models(e.g.numerical finite element method(FEM)model)to accurately predict time-varying ge... The development of digital twins for geotechnical structures necessitates the real-time updates of threedimensional(3D)virtual models(e.g.numerical finite element method(FEM)model)to accurately predict time-varying geotechnical responses(e.g.consolidation settlement)in a 3D spatial domain.However,traditional 3D numerical model updating approaches are computationally prohibitive and therefore difficult to update the 3D responses in real time.To address these challenges,this study proposes a novel machine learning framework called sparse dictionary learning(T-3D-SDL)for real-time updating of time-varying 3D geotechnical responses.In T-3D-SDL,a concerned dataset(e.g.time-varying 3D settlement)is approximated as a linear superposition of dictionary atoms generated from 3D random FEM analyses.Field monitoring data are then used to identify non-trivial atoms and estimate their weights within a Bayesian framework for model updating and prediction.The proposed approach enables the real-time update of temporally varying settlements with a high 3D spatial resolution and quantified uncertainty as field monitoring data evolve.The proposed approach is illustrated using an embankment construction project.The results show that the proposed approach effectively improves settlement predictions along temporal and 3D spatial dimensions,with minimal latency(e.g.within minutes),as monitoring data appear.In addition,the proposed approach requires only a reasonably small number of 3D FEM model evaluations,avoids the use of widely adopted yet often criticized surrogate models,and effectively addresses the limitations(e.g.computational inefficiency)of existing 3D model updating approaches. 展开更多
关键词 digital twin three-dimensional(3D)finite element method(FEM) Time-varying 3D settlement Real-time model update Sparse dictionary learning(SDL)
在线阅读 下载PDF
Glasses-free three-dimensional laparoscopic systems in oncologic surgery:Innovation or equivalence?
17
作者 Gustavo Eder González Alvarez Christian Ramírez Sánchez +3 位作者 Melissa Martínez Nieto Mario A Alarcón-Sánchez Juan JoséVarela-Hernández Sarah M LomelíMartínez 《World Journal of Gastrointestinal Surgery》 2025年第11期6-11,共6页
The development of minimally invasive surgery has transformed the management of gastrointestinal cancer.Notably,three-dimensional visualization systems have increased surgical precision.This editorial discusses a rece... The development of minimally invasive surgery has transformed the management of gastrointestinal cancer.Notably,three-dimensional visualization systems have increased surgical precision.This editorial discusses a recent study by Shen and Zhang,which compared the clinical applications of naked-eye threedimensional laparoscopic systems vs traditional optical systems in radical surgery for gastric and colorectal cancer.Both systems appeared to yield comparable surgical and oncological outcomes in terms of safety parameters,operating times,and quality of lymph node dissection.However,the spectacle-free system’s technical and logistical limitations hindered its effects on the surgical team’s overall competency.This editorial examines the authors’findings within the broader context of the evolution of oncologic laparoscopy,discusses the relevance of the results in light of the current literature,and proposes future research directions focused on multicenter validation,comprehensive ergonomic analysis,and technological advancements aimed at enhancing intraoperative collaboration.As technology continues to evolve,clinical implementation of new methods must be supported by robust scientific evidence and standardized criteria,to ensure tangible improvements in efficiency,safety,and oncologic outcomes. 展开更多
关键词 Autostereoscopic three-dimensional technology Laparoscopic surgery three-dimensional laparoscopy Twodimensional laparoscopy Oncologic surgery
暂未订购
Investigation into the degradation of 2,4,6-trichlorophenol utilizing a three-dimensional electrocatalytic reactor filled with fluorine-doped copper-carbon particle electrodes
18
作者 Hongrui Zhang Wenyu Huang +4 位作者 Hainong Song Hanhui Yan Jia Zhang Fang Zhong Huilan Li 《Journal of Environmental Sciences》 2025年第9期701-719,共19页
The three-dimensional particle electrode system exhibits significant potential for application in the treatment of wastewater.Nonetheless,the advancement of effective granular electrodes characterized by elevated cata... The three-dimensional particle electrode system exhibits significant potential for application in the treatment of wastewater.Nonetheless,the advancement of effective granular electrodes characterized by elevated catalytic activity and minimal energy consumption continues to pose a significant challenge.In this research,Fluorine-doped copper-carbon(F/Cu-GAC)particle electrodes were effectively synthesized through an impregnationcalcination technique,utilizing granular activated carbon as the carrier and fluorinedoped modified copper oxides as the catalytic agents.The particle electrodes were subsequently utilized to promote the degradation of 2,4,6-trichlorophenol(2,4,6-TCP)in a threedimensional electrocatalytic reactor(3DER).The F/Cu-GAC particle electrodes were polarized under the action of electric field,which promoted the heterogeneous Fenton-like reaction in which H2O2 generated by two-electron oxygen reduction reaction(2e-ORR)of O_(2) was catalytically decomposed to·OH.The 3DER equipped with F/Cu-GAC particle electrodes showed 100%removal of 2,4,6-TCP and 79.24%removal of TOC with a specific energy consumption(EC)of approximately 0.019 kWh/g·COD after 2 h of operation.The F/Cu-GAC particle electrodes exhibited an overpotential of 0.38 V and an electrochemically active surface area(ECSA)of 715 cm^(2),as determined through linear sweep voltammetry(LSV)and cyclic voltammetry(CV)assessments.These findings suggest a high level of electrocatalytic performance.Furthermore,the catalytic mechanism of the 3DER equipped with F/Cu-GAC particle electrodes was elucidated through the application of X-ray photoelectron spectroscopy(XPS),electron spin resonance(ESR),and active species capture experiments.This investigation offers a novel approach for the effective degradation of 2,4,6-TCP. 展开更多
关键词 2 4 6-TRICHLOROPHENOL Heterogeneous Fenton-like process three-dimensional electrocatalytic reactor three-dimensional particle electrode system Fluorine-doped copper-carbon particle electrodes
原文传递
A three-dimensional digital visualization model of cervical nerves in a healthy person 被引量:1
19
作者 Jiaming Cao Dong Fu Sen Li 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第20期1829-1836,共8页
Three-dimensional reconstruction nerve models are classically obtained from two-dimensional images of "visible human" frozen sections. However, because of the flexibility of nerve tissues and small color differences... Three-dimensional reconstruction nerve models are classically obtained from two-dimensional images of "visible human" frozen sections. However, because of the flexibility of nerve tissues and small color differences compared with surrounding tissues, the integrity and validity of nerve tissues can be impaired during milling. Thus, in the present study, we obtained two-dimensional data from a healthy volunteer based on continuous CT angiography and magnetic resonance myelography. Semi-automatic segmentation and reconstruction were then conducted at different thresholds in different tissues using Mimics software. Small anatomical structures such as muscles and cervical nerves were reconstructed using the medical computer aided design module. Three-dimensional digital models of the cervical nerves and their surrounding structures were successfully developed, which allowed visualization of the spatial relation of anatomical structures with a strong three-dimensional effect, distinct appearance, clear distribution, and good continuity, precision, and integrality. These results indicate the validity of a three-dimensional digital visualization model of healthy human cervical nerves, which overcomes the disadvantages of milling, avoids data loss, and exhibits a realistic appearance and three-dimensional image. 展开更多
关键词 neural regeneration CERVICAL three-dimension CT magnetic resonance myelography cervical plexus phrenic nerve vagus nerve recurrent laryngeal nerve GANGLION stellate ganglion grants-supported paper NEUROREGENERATION
暂未订购
上一页 1 2 250 下一页 到第
使用帮助 返回顶部