To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D lea...To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D leader-following cooperative interception guidance law.First,in the LOS direction of the leader,an impact time-controlled guidance law is derived based on the fixed-time stability theory,which enables the leader to complete the interception task at a prespecified impact time.Next,in the LOS direction of the followers,by introducing a time consensus tracking error function,a fixed-time consensus tracking guidance law is investigated to guarantee the consensus tracking convergence of the time-to-go.Then,in the direction normal to the LOS,by combining the designed global integral sliding mode surface and the second-order Sliding Mode Control(SMC)theory,an innovative 3D LOS-angle-constrained interception guidance law is developed,which eliminates the reaching phase in the traditional sliding mode guidance laws and effectively saves energy consumption.Moreover,it effectively suppresses the chattering phenomenon while avoiding the singularity issue,and compensates for unknown interference caused by target maneuvering online,making it convenient for practical engineering applications.Finally,theoretical proof analysis and multiple sets of numerical simulation results verify the effectiveness,superiority,and robustness of the investigated guidance law.展开更多
Experts and officials shared their insights on poverty reduction cooperation and sustainable development during the 2025 International Seminar on Global Poverty Reduction Partnerships.
A three-dimensional path-planning approach has been developed to coordinate multiple fixed-wing unmanned aerial vehicles(UAVs)while avoiding collisions.The hierarchical path-planning architecture that divides the path...A three-dimensional path-planning approach has been developed to coordinate multiple fixed-wing unmanned aerial vehicles(UAVs)while avoiding collisions.The hierarchical path-planning architecture that divides the path-planning process into two layers is proposed by designing the velocityobstacle strategy for satisfying timeliness and effectiveness.The upper-level layer focuses on creating an efficient Dubins initial path considering the dynamic constraints of the fixed wing.Subsequently,the lower-level layer detects potential collisions and adjusts its flight paths to avoid collisions by using the threedimensional velocity obstacle method,which describes the maneuvering space of collision avoidance as the intersection space of half space.To further handle the dynamic and collisionavoidance constraints,a priority mechanism is designed to ensure that the adjusted path is still feasible for fixed-wing UAVs.Simulation experiments demonstrate the effectiveness of the proposed method.展开更多
Intercepting high-maneuverability hypersonic targets in near-space environments poses significant challenges due to their extreme speeds and evasive capabilities.To address these challenges,this study presents an inte...Intercepting high-maneuverability hypersonic targets in near-space environments poses significant challenges due to their extreme speeds and evasive capabilities.To address these challenges,this study presents an integrated approach that combines a Three-Dimensional Finite-Time Optimal Cooperative Guidance Law(FTOC)with an Information Fusion Anti-saturation Predefined-time Observer(IFAPO).The proposed FTOC guidance law employs a nonlinear,non-quadratic finite-time optimal control strategy designed for rapid convergence within the limited timeframes of near-space interceptions,avoiding the need for remaining flight time estimation or linear decoupling inherent in traditional methods.To complement the guidance strategy,the IFAPO leverages multi-source information fusion theory and incorporates anti-saturation mechanisms to enhance target maneuver estimation.This method ensures accurate and real-time prediction of target acceleration while maintaining predefined convergence performance,even under complex interception conditions.By integrating the FTOC guidance law and IFAPO,the approach optimizes cooperative missile positioning,improves interception success rates,and minimizes fuel consumption,addressing practical constraints in military applications.Simulation results and comparative analyses confirm the effectiveness of the integrated approach,demonstrating its capability to achieve cooperative interception of highly maneuvering targets with enhanced efficiency and reduced economic costs,aligning with realistic combat scenarios.展开更多
In this article,a three-dimensional cooperative guidance problem for highly maneuvering targets is investigated under the assumption of perfect information.Inspired by the coverage strategy,the cooperative guidance pr...In this article,a three-dimensional cooperative guidance problem for highly maneuvering targets is investigated under the assumption of perfect information.Inspired by the coverage strategy,the cooperative guidance problem is decomposed into one-on-one guidance problems against predictive interception points.To expand the coverage area of each missile,these one-on-one guidance problems are formulated as flight path angle tracking problems,and the optimal error dynamics is extended to derive the guidance law analytically.In addition,through the introduction of the coverage probability model,the dynamic coverage strategy is proposed.The predictive interception points are updated online by maximizing the coverage probability,which aims to achieve successful interception despite variations in target acceleration.Furthermore,a switching strategy of the guidance command is designed for collision avoidance.Simulation results demonstrate that the missile group can cooperatively intercept a highly maneuvering target under the proposed guidance law.展开更多
In order to simultaneously attack a target with impact angle constraint in threedimensional(3-D) space, a novel distributed cooperative guidance law for multiple missiles under directed communication topologies is pro...In order to simultaneously attack a target with impact angle constraint in threedimensional(3-D) space, a novel distributed cooperative guidance law for multiple missiles under directed communication topologies is proposed without radial velocity measurements. First, based on missiles-target 3-D relative motion equations, the multiple missiles cooperative guidance model with impact angle constraint is constructed. Then, in Line-of-Sight(LOS) direction, based on multiagent system cooperative control theory, one guidance law with directed topologies is designed with strict proof, which can guarantee finite time consensus of multiple missiles' impact times. Next, in elevation direction and azimuth direction of LOS, based on homogeneous system stability theory and integral sliding mode control theory, two guidance laws are proposed respectively with strict proof, which can guarantee LOS angles converge to desired values and LOS angular rates converge to zero in finite time. Finally, the effectiveness of the designed cooperative guidance law is demonstrated through simulation results.展开更多
This paper presents the cooperative strategies for salvo attack of multiple missiles based on the classical proportional navigation（PN） algorithm.The three-dimensional（3-D） guidance laws are developed in a quite s...This paper presents the cooperative strategies for salvo attack of multiple missiles based on the classical proportional navigation（PN） algorithm.The three-dimensional（3-D） guidance laws are developed in a quite simple formulation that consists of a PN component for target capture and a coordination component for simultaneous arrival.The centralized algorithms come into effect when the global information of time-to-go estimation is obtained, whereas the decentralized algorithms have better performance when each missile can only collect information from neighbors.Numerical simulations demonstrate that the proposed coordination algorithms are feasible to perform the cooperative engagement of multiple missiles against both stationary and maneuvering targets.The effectiveness of the 3-D guidance laws is also discussed.展开更多
Cooperative interception of the target with strong maneuverability by multiple missiles with weak maneuverability in the three-dimensional nonlinear model is studied.Firstly,the three-dimensional nonlinear model of co...Cooperative interception of the target with strong maneuverability by multiple missiles with weak maneuverability in the three-dimensional nonlinear model is studied.Firstly,the three-dimensional nonlinear model of cooperative guidance is established.The three-dimensional reachable region is represented composed of lateral acceleration and longitudinal acceleration in the two-dimensional coordinate system.Secondly,the problem of the multiple missile’s reachable coverage area is transformed into the problem of cooperative coverage.A cooperative coverage strategy is proposed and an algorithm for quickly calculating the number of required missiles is designed.Then,the guidance law based on the cooperative coverage strategy is proposed,and it is proved that cooperative interception of the target can be achieved under the acceleration limit.Moreover,the relations among the number of missiles,the initial array position of terminal guidance and the coverage area of the target’s large maneuver are analyzed.The dynamic adjustment strategy of guidance parameters is proposed to reduce the guidance error.Finally,simulation results show that multiple missiles with low maneuverability can achieve effective interception of target with strong maneuverability through the proposed cooperative strategy and cooperative guidance method.展开更多
Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significan...Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significant gap in detailed and consistent data on 3D building space structures with global coverage due to the challenges inherent in the data collection and model calibration processes.In this study,we constructed a global urban structure(GUS-3D)dataset,including building volume,height,and footprint information,at a 500 m spatial resolution using extensive satellite observation products and numerous reference building samples.Our analysis indicated that the total volume of buildings worldwide in2015 exceeded 1×10^(12)m^(3).Over the 1985 to 2015 period,we observed a slight increase in the magnitude of 3D building volume growth(i.e.,it increased from 166.02 km3 during the 1985–2000 period to 175.08km3 during the 2000–2015 period),while the expansion magnitudes of the two-dimensional(2D)building footprint(22.51×10^(3) vs 13.29×10^(3)km^(2))and urban extent(157×10^(3) vs 133.8×10^(3)km^(2))notably decreased.This trend highlights the significant increase in intensive vertical utilization of urban land.Furthermore,we identified significant heterogeneity in building space provision and inequality across cities worldwide.This inequality is particularly pronounced in many populous Asian cities,which has been overlooked in previous studies on economic inequality.The GUS-3D dataset shows great potential to deepen our understanding of the urban environment and creates new horizons for numerous 3D urban studies.展开更多
Cell adhesion plays pivotal roles in the morphogenesis of multicellular organisms.Epithelial cells form several types of cell-to-cell adhesion,including zonula occludens(tight junctions),zonula adhaerens(adherens junc...Cell adhesion plays pivotal roles in the morphogenesis of multicellular organisms.Epithelial cells form several types of cell-to-cell adhesion,including zonula occludens(tight junctions),zonula adhaerens(adherens junctions),and macula adhaerens(desmosomes).Although these adhesion complexes are basically observed only in epithelial cells,cadherins,which are the major cell adhesion molecules of adherens junctions,are expressed in both epithelial and non-epithelial tissues,including neural tissues(Kawauchi,2012).The cadherin superfamily consists of more than 100 members,but classic cadherins.展开更多
This paper proposes a cooperative guidance law for attacking a ground target with the impact angle constraint based on the motion camouflage strategy in the line-of-sight(LOS)frame.A dynamic model with the impact angl...This paper proposes a cooperative guidance law for attacking a ground target with the impact angle constraint based on the motion camouflage strategy in the line-of-sight(LOS)frame.A dynamic model with the impact angle constraint is established according to the relative motion between multiple missiles and the target.The process of cooperative guidance law design is divided into two stages.Firstly,based on the undirected graph theory,a new finite-time consensus protocol on the LOS direction is derived to guarantee relative distances reach consensus.And the value of acceleration command is positive,which is beneficial for engineering realization.Secondly,the acceleration command on the normal direction of the LOS is designed based on motion camouflage and finite-time convergence,which can ensure the missiles reach the target with the desired angle and satisfy the motion camouflage state.The finitetime stability analysis is proved by the Lyapunov theory.Numerical simulations for stationary and maneuver targets have demonstrated the effectiveness of the cooperative guidance law proposed.展开更多
The paper presents a new three-dimensional (3D) cooperative guidance approach by the receding horizon control (RHC) technique. The objective is to coordinate the impact time of a group of interceptor missiles against ...The paper presents a new three-dimensional (3D) cooperative guidance approach by the receding horizon control (RHC) technique. The objective is to coordinate the impact time of a group of interceptor missiles against the stationary target. The framework of a distributed RHC scheme is developed, in which each interceptor missile is assigned its own finite-horizon optimal control problem (FHOCP) and only shares the information with its neighbors. The solution of the local FHOCP is obtained by the constrained particle swarm optimization (PSO) method that is integrated into the distributed RHC framework with enhanced equality and inequality constraints. The numerical simulations show that the proposed guidance approach is feasible to implement the cooperative engagement with satisfied accuracy of target capture. Finally, the computation efficiency of the distributed RHC scheme is discussed in consideration of the PSO parameters, control update period and prediction horizon. (C) 2016 Chinese Society of Aeronautics and Astronautics. Production and hosting by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.展开更多
Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma ...Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma pathobiology.Conventional cell culture-based research(2D cell culture)is still playing a pivotal role,while several shortcomings have been recently under discussion.In vivo,mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell culture.However,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)characteristics.Therefore,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and in vivo animal models and fill in the gap between them.Given the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor Organoids(PDOs),represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy development.In this review,we first provide a general overview of 3D cell cultures compared to 2D cell cultures.We then focus on one of the recent 3D cell culture applications,Patient-Derived Organoids(PDOs),summarizing and discussing several PDO methodologies.Finally,we discuss the current and future applications of PDOs to sarcoma,particularly in the field of liposarcoma.展开更多
The space-air-ground integrated network(SAGIN)combines the superiority of the satellite,aerial,and ground communications,which is envisioned to provide high-precision positioning ability as well as seamless connectivi...The space-air-ground integrated network(SAGIN)combines the superiority of the satellite,aerial,and ground communications,which is envisioned to provide high-precision positioning ability as well as seamless connectivity in the 5G and Beyond 5G(B5G)systems.In this paper,we propose a three-dimensional SAGIN localization scheme for ground agents utilizing multi-source information from satellites,base stations and unmanned aerial vehicles(UAVs).Based on the designed scheme,we derive the positioning performance bound and establish a distributed maximum likelihood algorithm to jointly estimate the positions and clock offsets of ground agents.Simulation results demonstrate the validity of the SAGIN localization scheme and reveal the effects of the number of satellites,the number of base stations,the number of UAVs and clock noise on positioning performance.展开更多
This paper investigates the problem of distributed cooperative guidance law design for multiple anti-ship missiles in the three-dimensional(3-D)space hitting simultaneously the same target with considering the desired...This paper investigates the problem of distributed cooperative guidance law design for multiple anti-ship missiles in the three-dimensional(3-D)space hitting simultaneously the same target with considering the desired terminal impact angle constraint.To address this issue,the problem formulation including 3-D nonlinear mathematical model description,and communication topology are built firstly.Then the consensus variable is constructed using the available information and can reach consensus under the proposed acceleration command along the line-of-sight(LOS)which satisfies the impact time constraint.However,the normal accelerations are designed to guarantee the convergence of the LOS angular rate.Furthermore,consider the terminal impact angle constraints,a nonsingular terminal sliding mode(NTSM)control is introduced,and a finite time convergent control law of normal acceleration is proposed.The convergence of the proposed guidance law is proved by using the second Lyapunov stability method,and numerical simulations are also conducted to verify its effectiveness.The results indicate that the proposed cooperative guidance law can regulate the impact time error and impact angle error in finite time if the connecting time of the communication topology is longer than the required convergent time.展开更多
Both China and Indonesia are influential maritime powers in the Asia-Pacific region.Strengthening practical maritime cooperation is highly significant to both sides as an important component of comprehensive strategic...Both China and Indonesia are influential maritime powers in the Asia-Pacific region.Strengthening practical maritime cooperation is highly significant to both sides as an important component of comprehensive strategic cooperation.Maritime cooperation has become a prominent part of the“five pillar”cooperation framework between the two countries alongside political,economic,people-to-people exchange,and security,playing a positive role in elevating the China-Indonesia comprehensive strategic partnership to a higher level.展开更多
On September 1st,the 18th Chi na-LAC Business Summit Promotion Conference opened in Beijing.Chinese and foreign vips gathered to prepare for the 18th China LAC Business Summit,planned for Zhengzhou,Henan,from Novemb...On September 1st,the 18th Chi na-LAC Business Summit Promotion Conference opened in Beijing.Chinese and foreign vips gathered to prepare for the 18th China LAC Business Summit,planned for Zhengzhou,Henan,from November 3rd to 4th.展开更多
The development of minimally invasive surgery has transformed the management of gastrointestinal cancer.Notably,three-dimensional visualization systems have increased surgical precision.This editorial discusses a rece...The development of minimally invasive surgery has transformed the management of gastrointestinal cancer.Notably,three-dimensional visualization systems have increased surgical precision.This editorial discusses a recent study by Shen and Zhang,which compared the clinical applications of naked-eye threedimensional laparoscopic systems vs traditional optical systems in radical surgery for gastric and colorectal cancer.Both systems appeared to yield comparable surgical and oncological outcomes in terms of safety parameters,operating times,and quality of lymph node dissection.However,the spectacle-free system’s technical and logistical limitations hindered its effects on the surgical team’s overall competency.This editorial examines the authors’findings within the broader context of the evolution of oncologic laparoscopy,discusses the relevance of the results in light of the current literature,and proposes future research directions focused on multicenter validation,comprehensive ergonomic analysis,and technological advancements aimed at enhancing intraoperative collaboration.As technology continues to evolve,clinical implementation of new methods must be supported by robust scientific evidence and standardized criteria,to ensure tangible improvements in efficiency,safety,and oncologic outcomes.展开更多
The year 2025 marks the 50th anniversary of the establishment of diplomatic relations between China and Thailand,as well as the“Golden Jubilee of Sino-Thai Friendship”.Over the past half-century,the scale and scope ...The year 2025 marks the 50th anniversary of the establishment of diplomatic relations between China and Thailand,as well as the“Golden Jubilee of Sino-Thai Friendship”.Over the past half-century,the scale and scope of economic and trade cooperation between China and Thailand have dramatically expanded.Both nations have strengthened their bilateral economic ties,which have increasingly strengthened their interdependence and.complementarity,presenting a broad prospect of mutual benefit and win-win cooperation.展开更多
Since the resumption of diplomatic relations between China and Indonesia in the 1990s,the economic and trade cooperation between the two countries has developed rapidly and continuously.Since 2013,the scale of trade b...Since the resumption of diplomatic relations between China and Indonesia in the 1990s,the economic and trade cooperation between the two countries has developed rapidly and continuously.Since 2013,the scale of trade between the two countries has expanded year on year,and investment has broadened from traditional agriculture and industry to the digital economy and financial insurance,which has effectively promoted industrial development in both countries.More infrastructure cooperation has significantly improved the development environment in Indonesia,producing tangible benefits for the local people.Different types of special economic zones have facilitated breakthrough development for Indonesian industries while creating employment opportunities for local residents and driving local economic development.展开更多
文摘To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D leader-following cooperative interception guidance law.First,in the LOS direction of the leader,an impact time-controlled guidance law is derived based on the fixed-time stability theory,which enables the leader to complete the interception task at a prespecified impact time.Next,in the LOS direction of the followers,by introducing a time consensus tracking error function,a fixed-time consensus tracking guidance law is investigated to guarantee the consensus tracking convergence of the time-to-go.Then,in the direction normal to the LOS,by combining the designed global integral sliding mode surface and the second-order Sliding Mode Control(SMC)theory,an innovative 3D LOS-angle-constrained interception guidance law is developed,which eliminates the reaching phase in the traditional sliding mode guidance laws and effectively saves energy consumption.Moreover,it effectively suppresses the chattering phenomenon while avoiding the singularity issue,and compensates for unknown interference caused by target maneuvering online,making it convenient for practical engineering applications.Finally,theoretical proof analysis and multiple sets of numerical simulation results verify the effectiveness,superiority,and robustness of the investigated guidance law.
文摘Experts and officials shared their insights on poverty reduction cooperation and sustainable development during the 2025 International Seminar on Global Poverty Reduction Partnerships.
基金supported by the National Science Fund for Distinguished Young Scholars(52425211)BIT Research Fund Program for Young Scholars(XSQD-202201005).
文摘A three-dimensional path-planning approach has been developed to coordinate multiple fixed-wing unmanned aerial vehicles(UAVs)while avoiding collisions.The hierarchical path-planning architecture that divides the path-planning process into two layers is proposed by designing the velocityobstacle strategy for satisfying timeliness and effectiveness.The upper-level layer focuses on creating an efficient Dubins initial path considering the dynamic constraints of the fixed wing.Subsequently,the lower-level layer detects potential collisions and adjusts its flight paths to avoid collisions by using the threedimensional velocity obstacle method,which describes the maneuvering space of collision avoidance as the intersection space of half space.To further handle the dynamic and collisionavoidance constraints,a priority mechanism is designed to ensure that the adjusted path is still feasible for fixed-wing UAVs.Simulation experiments demonstrate the effectiveness of the proposed method.
基金supported by the National Natural Science Foundation of China(Grant No.61773142).
文摘Intercepting high-maneuverability hypersonic targets in near-space environments poses significant challenges due to their extreme speeds and evasive capabilities.To address these challenges,this study presents an integrated approach that combines a Three-Dimensional Finite-Time Optimal Cooperative Guidance Law(FTOC)with an Information Fusion Anti-saturation Predefined-time Observer(IFAPO).The proposed FTOC guidance law employs a nonlinear,non-quadratic finite-time optimal control strategy designed for rapid convergence within the limited timeframes of near-space interceptions,avoiding the need for remaining flight time estimation or linear decoupling inherent in traditional methods.To complement the guidance strategy,the IFAPO leverages multi-source information fusion theory and incorporates anti-saturation mechanisms to enhance target maneuver estimation.This method ensures accurate and real-time prediction of target acceleration while maintaining predefined convergence performance,even under complex interception conditions.By integrating the FTOC guidance law and IFAPO,the approach optimizes cooperative missile positioning,improves interception success rates,and minimizes fuel consumption,addressing practical constraints in military applications.Simulation results and comparative analyses confirm the effectiveness of the integrated approach,demonstrating its capability to achieve cooperative interception of highly maneuvering targets with enhanced efficiency and reduced economic costs,aligning with realistic combat scenarios.
基金supported by the National Natural Science Foundation of China(Nos.61773142,62303136)China Postdoctoral Science Foundation(No.2023M740912)Postdoctoral Fellowship Program of CPSF,China(No.GZC20233447).
文摘In this article,a three-dimensional cooperative guidance problem for highly maneuvering targets is investigated under the assumption of perfect information.Inspired by the coverage strategy,the cooperative guidance problem is decomposed into one-on-one guidance problems against predictive interception points.To expand the coverage area of each missile,these one-on-one guidance problems are formulated as flight path angle tracking problems,and the optimal error dynamics is extended to derive the guidance law analytically.In addition,through the introduction of the coverage probability model,the dynamic coverage strategy is proposed.The predictive interception points are updated online by maximizing the coverage probability,which aims to achieve successful interception despite variations in target acceleration.Furthermore,a switching strategy of the guidance command is designed for collision avoidance.Simulation results demonstrate that the missile group can cooperatively intercept a highly maneuvering target under the proposed guidance law.
基金supported by the National Natural Science Foundation of China(Nos.61603114,61673135)
文摘In order to simultaneously attack a target with impact angle constraint in threedimensional(3-D) space, a novel distributed cooperative guidance law for multiple missiles under directed communication topologies is proposed without radial velocity measurements. First, based on missiles-target 3-D relative motion equations, the multiple missiles cooperative guidance model with impact angle constraint is constructed. Then, in Line-of-Sight(LOS) direction, based on multiagent system cooperative control theory, one guidance law with directed topologies is designed with strict proof, which can guarantee finite time consensus of multiple missiles' impact times. Next, in elevation direction and azimuth direction of LOS, based on homogeneous system stability theory and integral sliding mode control theory, two guidance laws are proposed respectively with strict proof, which can guarantee LOS angles converge to desired values and LOS angular rates converge to zero in finite time. Finally, the effectiveness of the designed cooperative guidance law is demonstrated through simulation results.
基金supported by the National Natural Science Foundation of China (Nos.61273349, 61203223)
文摘This paper presents the cooperative strategies for salvo attack of multiple missiles based on the classical proportional navigation（PN） algorithm.The three-dimensional（3-D） guidance laws are developed in a quite simple formulation that consists of a PN component for target capture and a coordination component for simultaneous arrival.The centralized algorithms come into effect when the global information of time-to-go estimation is obtained, whereas the decentralized algorithms have better performance when each missile can only collect information from neighbors.Numerical simulations demonstrate that the proposed coordination algorithms are feasible to perform the cooperative engagement of multiple missiles against both stationary and maneuvering targets.The effectiveness of the 3-D guidance laws is also discussed.
基金supported by the Science and Technology Innovation 2030-Key Project of‘‘New Generation Artificial Intelligence”,China(No.2020AAA0108204)the National Natural Science Foundation of China(Nos.61922008,61973013,61873011,61803014)+4 种基金the Innovation Zone Project,China(No.18-163-00-TS-001-001-34)the Defense Industrial TechnologyDevelopmentProgram,China(No.JCKY2019601C106)the Beijing Natural Science Foundation(No.4182035the Special Research Project of Chinese Civil Aircraft,China National Postdoctoral Program for Innovative Talents(No.BX20200034)Project funded by China Postdoctoral Science Foundation(No.2020 M680297)。
文摘Cooperative interception of the target with strong maneuverability by multiple missiles with weak maneuverability in the three-dimensional nonlinear model is studied.Firstly,the three-dimensional nonlinear model of cooperative guidance is established.The three-dimensional reachable region is represented composed of lateral acceleration and longitudinal acceleration in the two-dimensional coordinate system.Secondly,the problem of the multiple missile’s reachable coverage area is transformed into the problem of cooperative coverage.A cooperative coverage strategy is proposed and an algorithm for quickly calculating the number of required missiles is designed.Then,the guidance law based on the cooperative coverage strategy is proposed,and it is proved that cooperative interception of the target can be achieved under the acceleration limit.Moreover,the relations among the number of missiles,the initial array position of terminal guidance and the coverage area of the target’s large maneuver are analyzed.The dynamic adjustment strategy of guidance parameters is proposed to reduce the guidance error.Finally,simulation results show that multiple missiles with low maneuverability can achieve effective interception of target with strong maneuverability through the proposed cooperative strategy and cooperative guidance method.
基金supported by the National Science Fund for Distinguished Young Scholars(42225107)the National Natural Science Foundation of China(42001326,42371414,42171409,and 42271419)+1 种基金the Natural Science Foundation of Guangdong Province of China(2022A1515012207)the Basic and Applied Basic Research Project of Guangzhou Science and Technology Planning(202201011539)。
文摘Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significant gap in detailed and consistent data on 3D building space structures with global coverage due to the challenges inherent in the data collection and model calibration processes.In this study,we constructed a global urban structure(GUS-3D)dataset,including building volume,height,and footprint information,at a 500 m spatial resolution using extensive satellite observation products and numerous reference building samples.Our analysis indicated that the total volume of buildings worldwide in2015 exceeded 1×10^(12)m^(3).Over the 1985 to 2015 period,we observed a slight increase in the magnitude of 3D building volume growth(i.e.,it increased from 166.02 km3 during the 1985–2000 period to 175.08km3 during the 2000–2015 period),while the expansion magnitudes of the two-dimensional(2D)building footprint(22.51×10^(3) vs 13.29×10^(3)km^(2))and urban extent(157×10^(3) vs 133.8×10^(3)km^(2))notably decreased.This trend highlights the significant increase in intensive vertical utilization of urban land.Furthermore,we identified significant heterogeneity in building space provision and inequality across cities worldwide.This inequality is particularly pronounced in many populous Asian cities,which has been overlooked in previous studies on economic inequality.The GUS-3D dataset shows great potential to deepen our understanding of the urban environment and creates new horizons for numerous 3D urban studies.
基金funded by JSPS KAKENHI Grant Numbers JP26290015 and JP21H02655(to TK)from Ministry of Education,Culture,Sports,Science,and Technology of Japan(MEXT)。
文摘Cell adhesion plays pivotal roles in the morphogenesis of multicellular organisms.Epithelial cells form several types of cell-to-cell adhesion,including zonula occludens(tight junctions),zonula adhaerens(adherens junctions),and macula adhaerens(desmosomes).Although these adhesion complexes are basically observed only in epithelial cells,cadherins,which are the major cell adhesion molecules of adherens junctions,are expressed in both epithelial and non-epithelial tissues,including neural tissues(Kawauchi,2012).The cadherin superfamily consists of more than 100 members,but classic cadherins.
基金This work was supported by the National Nature Science Foundation of China(11572097).
文摘This paper proposes a cooperative guidance law for attacking a ground target with the impact angle constraint based on the motion camouflage strategy in the line-of-sight(LOS)frame.A dynamic model with the impact angle constraint is established according to the relative motion between multiple missiles and the target.The process of cooperative guidance law design is divided into two stages.Firstly,based on the undirected graph theory,a new finite-time consensus protocol on the LOS direction is derived to guarantee relative distances reach consensus.And the value of acceleration command is positive,which is beneficial for engineering realization.Secondly,the acceleration command on the normal direction of the LOS is designed based on motion camouflage and finite-time convergence,which can ensure the missiles reach the target with the desired angle and satisfy the motion camouflage state.The finitetime stability analysis is proved by the Lyapunov theory.Numerical simulations for stationary and maneuver targets have demonstrated the effectiveness of the cooperative guidance law proposed.
基金co-supported by the National Natural Science Foundation of China(Nos. 61273349 and 61573043)
文摘The paper presents a new three-dimensional (3D) cooperative guidance approach by the receding horizon control (RHC) technique. The objective is to coordinate the impact time of a group of interceptor missiles against the stationary target. The framework of a distributed RHC scheme is developed, in which each interceptor missile is assigned its own finite-horizon optimal control problem (FHOCP) and only shares the information with its neighbors. The solution of the local FHOCP is obtained by the constrained particle swarm optimization (PSO) method that is integrated into the distributed RHC framework with enhanced equality and inequality constraints. The numerical simulations show that the proposed guidance approach is feasible to implement the cooperative engagement with satisfied accuracy of target capture. Finally, the computation efficiency of the distributed RHC scheme is discussed in consideration of the PSO parameters, control update period and prediction horizon. (C) 2016 Chinese Society of Aeronautics and Astronautics. Production and hosting by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.
文摘Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma pathobiology.Conventional cell culture-based research(2D cell culture)is still playing a pivotal role,while several shortcomings have been recently under discussion.In vivo,mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell culture.However,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)characteristics.Therefore,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and in vivo animal models and fill in the gap between them.Given the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor Organoids(PDOs),represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy development.In this review,we first provide a general overview of 3D cell cultures compared to 2D cell cultures.We then focus on one of the recent 3D cell culture applications,Patient-Derived Organoids(PDOs),summarizing and discussing several PDO methodologies.Finally,we discuss the current and future applications of PDOs to sarcoma,particularly in the field of liposarcoma.
文摘The space-air-ground integrated network(SAGIN)combines the superiority of the satellite,aerial,and ground communications,which is envisioned to provide high-precision positioning ability as well as seamless connectivity in the 5G and Beyond 5G(B5G)systems.In this paper,we propose a three-dimensional SAGIN localization scheme for ground agents utilizing multi-source information from satellites,base stations and unmanned aerial vehicles(UAVs).Based on the designed scheme,we derive the positioning performance bound and establish a distributed maximum likelihood algorithm to jointly estimate the positions and clock offsets of ground agents.Simulation results demonstrate the validity of the SAGIN localization scheme and reveal the effects of the number of satellites,the number of base stations,the number of UAVs and clock noise on positioning performance.
文摘This paper investigates the problem of distributed cooperative guidance law design for multiple anti-ship missiles in the three-dimensional(3-D)space hitting simultaneously the same target with considering the desired terminal impact angle constraint.To address this issue,the problem formulation including 3-D nonlinear mathematical model description,and communication topology are built firstly.Then the consensus variable is constructed using the available information and can reach consensus under the proposed acceleration command along the line-of-sight(LOS)which satisfies the impact time constraint.However,the normal accelerations are designed to guarantee the convergence of the LOS angular rate.Furthermore,consider the terminal impact angle constraints,a nonsingular terminal sliding mode(NTSM)control is introduced,and a finite time convergent control law of normal acceleration is proposed.The convergence of the proposed guidance law is proved by using the second Lyapunov stability method,and numerical simulations are also conducted to verify its effectiveness.The results indicate that the proposed cooperative guidance law can regulate the impact time error and impact angle error in finite time if the connecting time of the communication topology is longer than the required convergent time.
文摘Both China and Indonesia are influential maritime powers in the Asia-Pacific region.Strengthening practical maritime cooperation is highly significant to both sides as an important component of comprehensive strategic cooperation.Maritime cooperation has become a prominent part of the“five pillar”cooperation framework between the two countries alongside political,economic,people-to-people exchange,and security,playing a positive role in elevating the China-Indonesia comprehensive strategic partnership to a higher level.
文摘On September 1st,the 18th Chi na-LAC Business Summit Promotion Conference opened in Beijing.Chinese and foreign vips gathered to prepare for the 18th China LAC Business Summit,planned for Zhengzhou,Henan,from November 3rd to 4th.
文摘The development of minimally invasive surgery has transformed the management of gastrointestinal cancer.Notably,three-dimensional visualization systems have increased surgical precision.This editorial discusses a recent study by Shen and Zhang,which compared the clinical applications of naked-eye threedimensional laparoscopic systems vs traditional optical systems in radical surgery for gastric and colorectal cancer.Both systems appeared to yield comparable surgical and oncological outcomes in terms of safety parameters,operating times,and quality of lymph node dissection.However,the spectacle-free system’s technical and logistical limitations hindered its effects on the surgical team’s overall competency.This editorial examines the authors’findings within the broader context of the evolution of oncologic laparoscopy,discusses the relevance of the results in light of the current literature,and proposes future research directions focused on multicenter validation,comprehensive ergonomic analysis,and technological advancements aimed at enhancing intraoperative collaboration.As technology continues to evolve,clinical implementation of new methods must be supported by robust scientific evidence and standardized criteria,to ensure tangible improvements in efficiency,safety,and oncologic outcomes.
文摘The year 2025 marks the 50th anniversary of the establishment of diplomatic relations between China and Thailand,as well as the“Golden Jubilee of Sino-Thai Friendship”.Over the past half-century,the scale and scope of economic and trade cooperation between China and Thailand have dramatically expanded.Both nations have strengthened their bilateral economic ties,which have increasingly strengthened their interdependence and.complementarity,presenting a broad prospect of mutual benefit and win-win cooperation.
文摘Since the resumption of diplomatic relations between China and Indonesia in the 1990s,the economic and trade cooperation between the two countries has developed rapidly and continuously.Since 2013,the scale of trade between the two countries has expanded year on year,and investment has broadened from traditional agriculture and industry to the digital economy and financial insurance,which has effectively promoted industrial development in both countries.More infrastructure cooperation has significantly improved the development environment in Indonesia,producing tangible benefits for the local people.Different types of special economic zones have facilitated breakthrough development for Indonesian industries while creating employment opportunities for local residents and driving local economic development.
