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Accurate closed-form flutter eigensolutions of three-dimensional composite laminates with shear deformation
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作者 Dezhuang PAN Yufeng XING 《Chinese Journal of Aeronautics》 2026年第1期230-246,共17页
According to the Mindlin plate theory and the first-order piston theory,this work obtains accurate closed-form eigensolutions for the flutter problem of three-dimensional(3D)rectangular laminated panels.The governing ... According to the Mindlin plate theory and the first-order piston theory,this work obtains accurate closed-form eigensolutions for the flutter problem of three-dimensional(3D)rectangular laminated panels.The governing differential equations are derived by the Hamilton's variational principle,and then solved by the iterative Separation-of-Variable(i SOV)method,which are applicable to arbitrary combinations of homogeneous Boundary Conditions(BCs).However,only the simply-support,clamped and cantilever panels are considered in this work for the sake of clarity.With the closed-form eigensolutions,the flutter frequency,flutter mode and flutter boundary are presented,and the effect of shear deformation and aerodynamic damping on flutter frequencies is investigated.Besides,the relation between panel energy and the work of aerodynamic load is discussed.The numerical comparisons reveal the following.(A)The flutter eigenvalues obtained by the present method are accurate,validated by the Finite Element Method(FEM)and the Galerkin method.(B)When the span-chord ratio is larger than 3,simplifying a 3D panel to 2D(two-dimensional)panel is reasonable and the relative differences of the flutter points predicted by the two models are less than one percent.(C)The reciprocal relationship between the mechanical energy of the panel and the work done by aerodynamic load is verified by using the present flutter eigenvalues and modes,further indicating the high accuracy of the present solutions.(D)The coupling of shear deformation and aerodynamic damping prevents frequency coalescing. 展开更多
关键词 Closed-form eigensolutions The first-order piston theory The Mindlin plate theory three-dimensional panel flutter Separation-of-variable method
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A MIXED FINITE ELEMENT AND UPWIND MIXED FINITE ELEMENT MULTI-STEP METHOD FOR THE THREE-DIMENSIONAL POSITIVE SEMI-DEFINITE DARCY-FORCHHEIMER MISCIBLE DISPLACEMENT PROBLEM
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作者 Yirang YUAN Changfeng LI +1 位作者 Huailing SONG Tongjun SUN 《Acta Mathematica Scientia》 2025年第2期715-736,共22页
In this paper,a composite numerical scheme is proposed to solve the threedimensional Darcy-Forchheimer miscible displacement problem with positive semi-definite assumptions.A mixed finite element is used for the fow e... In this paper,a composite numerical scheme is proposed to solve the threedimensional Darcy-Forchheimer miscible displacement problem with positive semi-definite assumptions.A mixed finite element is used for the fow equation.The velocity and pressure are computed simultaneously.The accuracy of velocity is improved one order.The concentration equation is solved by using mixed finite element,multi-step difference and upwind approximation.A multi-step method is used to approximate time derivative for improving the accuracy.The upwind approximation and an expanded mixed finite element are adopted to solve the convection and diffusion,respectively.The composite method could compute the diffusion flux and its gradient.It possibly becomes an eficient tool for solving convection-dominated diffusion problems.Firstly,the conservation of mass holds.Secondly,the multi-step method has high accuracy.Thirdly,the upwind approximation could avoid numerical dispersion.Using numerical analysis of a priori estimates and special techniques of differential equations,we give an error estimates for a positive definite problem.Numerical experiments illustrate its computational efficiency and feasibility of application. 展开更多
关键词 Darcy-Forchheimer fow three-dimensional positive semi-definite problem upwind mixed finite element multi-step method conservation of mass convergence analysis
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Mixed integer programming modeling for the satellite three-dimensional component assignment and layout optimization problem
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作者 Yufeng XIA Xianqi CHEN +3 位作者 Zhijia LIU Weien ZHOU Wen YAO Zhongneng ZHANG 《Chinese Journal of Aeronautics》 2025年第6期427-447,共21页
Satellite Component Layout Optimization(SCLO) is crucial in satellite system design.This paper proposes a novel Satellite Three-Dimensional Component Assignment and Layout Optimization(3D-SCALO) problem tailored to en... Satellite Component Layout Optimization(SCLO) is crucial in satellite system design.This paper proposes a novel Satellite Three-Dimensional Component Assignment and Layout Optimization(3D-SCALO) problem tailored to engineering requirements, aiming to optimize satellite heat dissipation while considering constraints on static stability, 3D geometric relationships between components, and special component positions. The 3D-SCALO problem is a challenging bilevel combinatorial optimization task, involving the optimization of discrete component assignment variables in the outer layer and continuous component position variables in the inner layer,with both influencing each other. To address this issue, first, a Mixed Integer Programming(MIP) model is proposed, which reformulates the original bilevel problem into a single-level optimization problem, enabling the exploration of a more comprehensive optimization space while avoiding iterative nested optimization. Then, to model the 3D geometric relationships between components within the MIP framework, a linearized 3D Phi-function method is proposed, which handles non-overlapping and safety distance constraints between cuboid components in an explicit and effective way. Subsequently, the Finite-Rectangle Method(FRM) is proposed to manage 3D geometric constraints for complex-shaped components by approximating them with a finite set of cuboids, extending the applicability of the geometric modeling approach. Finally, the feasibility and effectiveness of the proposed MIP model are demonstrated through two numerical examples"and a real-world engineering case, which confirms its suitability for complex-shaped components and real engineering applications. 展开更多
关键词 Mixed integer programming modeling three-dimensional component assignment Layout optimization Phi-function Finite-rectangle method
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Two kinds of contact problems in three-dimensional icosahedral quasicrystals 被引量:11
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作者 Xuefen ZHAO Xing LI Shenghu DING 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2015年第12期1569-1580,共12页
Two kinds of contact problems, i.e., the frictional contact problem and the adhesive contact problem, in three-dimensional (3D) icosahedral quasicrystals are dis- cussed by a complex variable function method. For th... Two kinds of contact problems, i.e., the frictional contact problem and the adhesive contact problem, in three-dimensional (3D) icosahedral quasicrystals are dis- cussed by a complex variable function method. For the frictional contact problem, the contact stress exhibits power singularities at the edge of the contact zone. For the adhe- sive contact problem, the contact stress exhibits oscillatory singularities at the edge of the contact zone. The numerical examples show that for the two kinds of contact problems, the contact stress exhibits singularities, and reaches the maximum value at the edge of the contact zone. The phonon-phason coupling constant has a significant effect on the contact stress intensity, while has little impact on the contact stress distribution regu- lation. The results are consistent with those of the classical elastic materials when the phonon-phason coupling constant is 0. For the adhesive contact problem, the indentation force has positive correlation with the contact displacement, but the phonon-phason cou- pling constant impact is barely perceptible. The validity of the conclusions is verified. 展开更多
关键词 three-dimensional (3D) icosahedral quasicrystal Riemann-Hilbert problem contact problem SINGULARITY complex variable function method
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Three-dimensional problem of transient contact dynamics 被引量:1
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作者 范天佑 H.G.Hahn A.Voigt 《Science China Mathematics》 SCIE 1996年第10期1096-1105,共10页
An analytic solution to three-dimensional problem of transient contact dynamics is developed, and a generalized Galin’s theorem is proved. Based on the theorem, contact displacements can be determined analytically wh... An analytic solution to three-dimensional problem of transient contact dynamics is developed, and a generalized Galin’s theorem is proved. Based on the theorem, contact displacements can be determined analytically when the given contact stresses are some quite general functions; in contrast to this, one can readily evaluate the corresponding contact stresses in analytic version when some quite general displacements are prescribed. The quite general form mentioned above means the prescribed quantities are any polynomials of x and y and any transient function of time. Numerical results for the contact displacements-time variation dearly demonstrate the effect of inertia induced by the dynamic stress. 展开更多
关键词 TRANSIENT dynamic CONTACT three-dimensional problem GENERALIZED Galin’s theorem.
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Three-dimensional line-of-sight-angle-constrained leader-following cooperative interception guidance law with prespecified impact time 被引量:3
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作者 Hao YOU Xinlong CHANG Jiufen ZHAO 《Chinese Journal of Aeronautics》 2025年第1期491-506,共16页
To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D lea... To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D leader-following cooperative interception guidance law.First,in the LOS direction of the leader,an impact time-controlled guidance law is derived based on the fixed-time stability theory,which enables the leader to complete the interception task at a prespecified impact time.Next,in the LOS direction of the followers,by introducing a time consensus tracking error function,a fixed-time consensus tracking guidance law is investigated to guarantee the consensus tracking convergence of the time-to-go.Then,in the direction normal to the LOS,by combining the designed global integral sliding mode surface and the second-order Sliding Mode Control(SMC)theory,an innovative 3D LOS-angle-constrained interception guidance law is developed,which eliminates the reaching phase in the traditional sliding mode guidance laws and effectively saves energy consumption.Moreover,it effectively suppresses the chattering phenomenon while avoiding the singularity issue,and compensates for unknown interference caused by target maneuvering online,making it convenient for practical engineering applications.Finally,theoretical proof analysis and multiple sets of numerical simulation results verify the effectiveness,superiority,and robustness of the investigated guidance law. 展开更多
关键词 three-dimensional cooperative interception Leader-following missiles Prespecified impact time LOS-angle-constrained Fixed-time stability Global integral sliding mode
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Meshless analysis of three-dimensional steady-state heat conduction problems 被引量:3
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作者 程荣军 葛红霞 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第9期36-41,共6页
Steady-state heat conduction problems arisen in connection with various physical and engineering problems where the functions satisfy a given partial differential equation and particular boundary conditions, have attr... Steady-state heat conduction problems arisen in connection with various physical and engineering problems where the functions satisfy a given partial differential equation and particular boundary conditions, have attracted much attention and research recently. These problems are independent of time and involve only space coordinates, as in Poisson's equation or the Laplace equation with Dirichlet, Neuman, or mixed conditions. When the problems are too complex, it is difficult to find an analytical solution, the only choice left is an approximate numerical solution. This paper deals with the numerical solution of three-dimensional steady-state heat conduction problems using the meshless reproducing kernel particle method (RKPM). A variational method is used to obtain the discrete equations. The essential boundary conditions are enforced by the penalty method. The effectiveness of RKPM for three-dimensional steady-state heat conduction problems is investigated by two numerical examples. 展开更多
关键词 reproducing kernel particle method meshless method steady-state heat conduction problem
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Global Mapping of Three-Dimensional Urban Structures Reveals Escalating Utilization in the Vertical Dimension and Pronounced Building Space Inequality 被引量:1
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作者 Xiaoping Liu Xinxin Wu +6 位作者 Xuecao Li Xiaocong Xu Weilin Liao Limin Jiao Zhenzhong Zeng Guangzhao Chen Xia Li 《Engineering》 2025年第4期86-99,共14页
Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significan... Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significant gap in detailed and consistent data on 3D building space structures with global coverage due to the challenges inherent in the data collection and model calibration processes.In this study,we constructed a global urban structure(GUS-3D)dataset,including building volume,height,and footprint information,at a 500 m spatial resolution using extensive satellite observation products and numerous reference building samples.Our analysis indicated that the total volume of buildings worldwide in2015 exceeded 1×10^(12)m^(3).Over the 1985 to 2015 period,we observed a slight increase in the magnitude of 3D building volume growth(i.e.,it increased from 166.02 km3 during the 1985–2000 period to 175.08km3 during the 2000–2015 period),while the expansion magnitudes of the two-dimensional(2D)building footprint(22.51×10^(3) vs 13.29×10^(3)km^(2))and urban extent(157×10^(3) vs 133.8×10^(3)km^(2))notably decreased.This trend highlights the significant increase in intensive vertical utilization of urban land.Furthermore,we identified significant heterogeneity in building space provision and inequality across cities worldwide.This inequality is particularly pronounced in many populous Asian cities,which has been overlooked in previous studies on economic inequality.The GUS-3D dataset shows great potential to deepen our understanding of the urban environment and creates new horizons for numerous 3D urban studies. 展开更多
关键词 three-dimensional Global mapping Building volume Building height Building space inequality
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Three-dimensional reconstruction under computed tomography and myopectineal orifice measurement under laparoscopy for quality control of inguinal hernia treatment 被引量:1
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作者 Lei Zhang Jing Chen +7 位作者 Yu-Ying Zhang Lei Liu Han-Dan Wang Ya-Fei Zhang Jun Sheng Qiu-Shi Hu Ming-Liang Liu Yi-Lin Yuan 《World Journal of Gastrointestinal Endoscopy》 2025年第3期50-59,共10页
BACKGROUND Inguinal hernias are common after surgery.Tension-free repair is widely accepted as the main method for managing inguinal hernias.Adequate exposure,coverage,and repair of the myopectineal orifice(MPO)are ne... BACKGROUND Inguinal hernias are common after surgery.Tension-free repair is widely accepted as the main method for managing inguinal hernias.Adequate exposure,coverage,and repair of the myopectineal orifice(MPO)are necessary.However,due to differences in race and sex,people’s body shapes vary.According to European guidelines,the patch should measure 10 cm×15 cm.If any part of the MPO is dissected,injury to the nerves,vascular network,or organs may occur during surgery,thereby leading to inguinal discomfort,pain,and seroma formation after surgery.Therefore,accurate localization and measurement of the boundary of the MPO are crucial for selecting the optimal patch for inguinal hernia repair.AIM To compare the size of the MPO measured on three-dimensional multislice spiral computed tomography(CT)with that measured via laparoscopy and explore the relevant factors influencing the size of the MPO.METHODS Clinical data from 74 patients who underwent laparoscopic tension-free inguinal hernia repair at the General Surgery Department of the First Affiliated Hospital of Anhui University of Science and Technology between September 2022 and July 2024 were collected and analyzed retrospectively.Transabdominal preperitoneal was performed.Sixty-four males and 10 females,with an average age of 58.30±12.32 years,were included.The clinical data of the patients were collected.The boundary of the MPO was measured on three-dimensional CT images before surgery and then again during transabdominal preperitoneal.All the preoperative and intraoperative data were analyzed via paired t-tests.A t-test was used for comparisons of age,body mass index,and sex between the groups.In the comparative analysis,a P value less than 0.05 indicated a significant difference.RESULTS The boundaries of the MPO on 3-dimensional CT images measured 7.05±0.47 cm and 6.27±0.61 cm,and the area of the MPO was 19.54±3.33 cm^(2).The boundaries of the MPO during surgery were 7.18±0.51 cm and 6.17±0.40 cm.The errors were not statistically significant.However,the intraoperative BD(the width of the MPO,P=0.024,P<0.05)and preoperative AC(the length of the MPO,P=0.045,P<0.05)significantly differed according to sex.The AC and BD measurements before and during surgery were not significantly different according to age,body mass index,hernia side or hernia type(P>0.05).CONCLUSION The application of this technology can aid in determining the most appropriate dissection range and patch size. 展开更多
关键词 HERNIA INGUINAL Myopectineal orifice three-dimensional reconstruction Computed tomography Inguinal hernia
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NUMERICAL METHOD OF MIXED FINITE VOLUME-MODIFIED UPWIND FRACTIONAL STEP DIFFERENCE FOR THREE-DIMENSIONAL SEMICONDUCTOR DEVICE TRANSIENT BEHAVIOR PROBLEMS 被引量:5
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作者 袁益让 杨青 +1 位作者 李长峰 孙同军 《Acta Mathematica Scientia》 SCIE CSCD 2017年第1期259-279,共21页
Transient behavior of three-dimensional semiconductor device with heat conduc- tion is described by a coupled mathematical system of four quasi-linear partial differential equations with initial-boundary value conditi... Transient behavior of three-dimensional semiconductor device with heat conduc- tion is described by a coupled mathematical system of four quasi-linear partial differential equations with initial-boundary value conditions. The electric potential is defined by an ellip- tic equation and it appears in the following three equations via the electric field intensity. The electron concentration and the hole concentration are determined by convection-dominated diffusion equations and the temperature is interpreted by a heat conduction equation. A mixed finite volume element approximation, keeping physical conservation law, is used to get numerical values of the electric potential and the accuracy is improved one order. Two con- centrations and the heat conduction are computed by a fractional step method combined with second-order upwind differences. This method can overcome numerical oscillation, dispersion and decreases computational complexity. Then a three-dimensional problem is solved by computing three successive one-dimensional problems where the method of speedup is used and the computational work is greatly shortened. An optimal second-order error estimate in L2 norm is derived by using prior estimate theory and other special techniques of partial differential equations. This type of mass-conservative parallel method is important and is most valuable in numerical analysis and application of semiconductor device. 展开更多
关键词 three dimensional transient behavior of heat conduction problem mixed finitevolume element modified upwind fractional step difference second-order error
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Solvability on boundary-value problems of elasticity of three-dimensional quasicrystals 被引量:1
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作者 郭丽辉 范天佑 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2007年第8期1061-1070,共10页
Weak solution (or generalized solution) for the boundary-value problems of partial differential equations of elasticity of 3D (three-dimensional) quasicrystals is given, in which the matrix expression is used. In ... Weak solution (or generalized solution) for the boundary-value problems of partial differential equations of elasticity of 3D (three-dimensional) quasicrystals is given, in which the matrix expression is used. In terms of Korn inequality and theory of function space, we prove the uniqueness of the weak solution. This gives an extension of existence theorem of solution for classical elasticity to that of quasicrystals, and develops the weak solution theory of elasticity of 2D quasicrystals given by the second author of the paper and his students. 展开更多
关键词 QUASICRYSTAL ELASTICITY boundary-value problem weak solution SOLVABILITY
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Factorization method for inverse obstacle scattering problem in three-dimensional planar acoustic waveguides 被引量:1
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作者 Xue Qin 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第10期130-140,共11页
In this paper, we consider the inverse scattering problem of reconstructing a bounded obstacle in a three-dimensional planar waveguide from the scattered near-field data measured on a finite cylindrical surface contai... In this paper, we consider the inverse scattering problem of reconstructing a bounded obstacle in a three-dimensional planar waveguide from the scattered near-field data measured on a finite cylindrical surface containing the obstacle and corresponding to infinitely many incident point sources also placed on the measurement surface. The obstacle is allowed to be an impenetrable scatterer or a penetrable scatterer. We establish the validity of the factorization method with the nearfield data to characterize the obstacle in the planar waveguide by constructing an outgoing-to-incoming operator which is an integral operator defined on the measurement surface with the kernel given in terms of an infinite series. 展开更多
关键词 factorization method planar waveguide inverse scattering problem
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Artificial intelligence-aided semi-automatic joint trace detection from textured three-dimensional models of rock mass 被引量:1
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作者 Seyedahmad Mehrishal Jineon Kim +1 位作者 Yulong Shao Jae Joon Song 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第4期1973-1985,共13页
It is of great importance to obtain precise trace data,as traces are frequently the sole visible and measurable parameter in most outcrops.The manual recognition and detection of traces on high-resolution three-dimens... It is of great importance to obtain precise trace data,as traces are frequently the sole visible and measurable parameter in most outcrops.The manual recognition and detection of traces on high-resolution three-dimensional(3D)models are relatively straightforward but time-consuming.One potential solution to enhance this process is to use machine learning algorithms to detect the 3D traces.In this study,a unique pixel-wise texture mapper algorithm generates a dense point cloud representation of an outcrop with the precise resolution of the original textured 3D model.A virtual digital image rendering was then employed to capture virtual images of selected regions.This technique helps to overcome limitations caused by the surface morphology of the rock mass,such as restricted access,lighting conditions,and shading effects.After AI-powered trace detection on two-dimensional(2D)images,a 3D data structuring technique was applied to the selected trace pixels.In the 3D data structuring,the trace data were structured through 2D thinning,3D reprojection,clustering,segmentation,and segment linking.Finally,the linked segments were exported as 3D polylines,with each polyline in the output corresponding to a trace.The efficacy of the proposed method was assessed using a 3D model of a real-world case study,which was used to compare the results of artificial intelligence(AI)-aided and human intelligence trace detection.Rosette diagrams,which visualize the distribution of trace orientations,confirmed the high similarity between the automatically and manually generated trace maps.In conclusion,the proposed semi-automatic method was easy to use,fast,and accurate in detecting the dominant jointing system of the rock mass. 展开更多
关键词 Automatic trace detection Digital joint mapping Rock discontinuities characterization three-dimensional(3D)trace network
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Dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions 被引量:1
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作者 Chentong GAO Huiyu SUN +1 位作者 Jianping GU W.M.HUANG 《Applied Mathematics and Mechanics(English Edition)》 2025年第1期123-138,共16页
Currently,there are a limited number of dynamic models available for braided composite plates with large overall motions,despite the incorporation of three-dimensional(3D)braided composites into rotating blade compone... Currently,there are a limited number of dynamic models available for braided composite plates with large overall motions,despite the incorporation of three-dimensional(3D)braided composites into rotating blade components.In this paper,a dynamic model of 3D 4-directional braided composite thin plates considering braiding directions is established.Based on Kirchhoff's plate assumptions,the displacement variables of the plate are expressed.By incorporating the braiding directions into the constitutive equation of the braided composites,the dynamic model of the plate considering braiding directions is obtained.The effects of the speeds,braiding directions,and braided angles on the responses of the plate with fixed-axis rotation and translational motion,respectively,are investigated.This paper presents a dynamic theory for calculating the deformation of 3D braided composite structures undergoing both translational and rotational motions.It also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications. 展开更多
关键词 three-dimensional(3D)braided composite braiding direction composite thin plate large overall motion dynamic model
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An Efficient Three-Dimensional Coupled Normal Mode Model and Its Application to Internal Solitary Wave Problems 被引量:1
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作者 Ze-Zhong Zhang Wen-Yu Luo Ren-He Zhang 《Chinese Physics Letters》 SCIE CAS CSCD 2018年第8期36-39,共4页
We present an efficient three-dimensional coupled-mode model based on the Fourier synthesis technique. In principle, this model is a one-way model, and hence provides satisfactory accuracy for problems where the forwa... We present an efficient three-dimensional coupled-mode model based on the Fourier synthesis technique. In principle, this model is a one-way model, and hence provides satisfactory accuracy for problems where the forward scattering dominates. At the same time, this model provides an efficiency gain of an order of magnitude or more over two-way coupled-mode models. This model can be applied to three-dimensional range-dependent problems with a slowly varying bathymetry or internal waves. A numerical example of the latter is demonstrated in this work. Comparisons of both accuracy and efficiency between the present model and a benchmark model are also provided. 展开更多
关键词 An Efficient three-dimensional Coupled Normal Mode Model and Its Application to Internal Solitary Wave problems
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Three-dimensional models:from cell culture to Patient-Derived Organoid and its application to future liposarcoma research
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作者 SAYUMI TAHARA SYDNEY RENTSCH +4 位作者 FERNANDA COSTAS CASAL DE FARIA PATRICIA SARCHET ROMA KARNA FEDERICA CALORE RAPHAEL E.POLLOCK 《Oncology Research》 SCIE 2025年第1期1-13,共13页
Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma ... Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma pathobiology.Conventional cell culture-based research(2D cell culture)is still playing a pivotal role,while several shortcomings have been recently under discussion.In vivo,mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell culture.However,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)characteristics.Therefore,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and in vivo animal models and fill in the gap between them.Given the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor Organoids(PDOs),represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy development.In this review,we first provide a general overview of 3D cell cultures compared to 2D cell cultures.We then focus on one of the recent 3D cell culture applications,Patient-Derived Organoids(PDOs),summarizing and discussing several PDO methodologies.Finally,we discuss the current and future applications of PDOs to sarcoma,particularly in the field of liposarcoma. 展开更多
关键词 Cell culture LIPOSARCOMA Patient-Derived Organoid(PDO) SPHEROID three-dimensional(3D)cell culture
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Theoretical researches on three-dimensional coda wave scattering problem 被引量:1
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作者 聂永安 曾健 冯德益 《Acta Seismologica Sinica(English Edition)》 CSCD 1995年第1期83-87,共5页
Based on the previous researches on scattering theory, a model of single and multiple scattering in a three-dimensional infinite medium with non-zero hypocentral distance is proposed in this paper. According to the as... Based on the previous researches on scattering theory, a model of single and multiple scattering in a three-dimensional infinite medium with non-zero hypocentral distance is proposed in this paper. According to the assumptionof three-dimensional medium with numerous, statistically isotropic and uniformly distributed scatterers, we obtain the analytic form of power spectrum of coda waves for single scattering and the integral form of power spectrum of coda waves for multiple scattering. 展开更多
关键词 coda wave three-dimensional model
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THE CAPTURE RANGES AND THE DANGEROUS RANGES FOR THE THREE-DIMENSIONAL TWO-AIRCRAFT COMBAT PROBLEM
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作者 Tong Minan and Wang LixinNorthwestern Polytechnical University 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 1990年第2期88-97,共10页
In this paper, we use differential game theory to study the three-dimensional two-aircraft air-to-air combat problem. We give the ways to determine the Capture Ranges (CR) and the Dangerous Ranges (DR) for these two a... In this paper, we use differential game theory to study the three-dimensional two-aircraft air-to-air combat problem. We give the ways to determine the Capture Ranges (CR) and the Dangerous Ranges (DR) for these two aircraft according to the target entry directions, barrier and isochronic lines respectively. The simulations are given by referring to two sets of real aircraft parameters. After discussing the simulation results, we have obtained some conclusions that match the real air-to-air combat situation quite well. 展开更多
关键词 CR DR THE CAPTURE RANGES AND THE DANGEROUS RANGES FOR THE three-dimensional TWO-AIRCRAFT COMBAT problem
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Exact analytical solution to three-dimensional phase change heat transfer problems in biological tissues subject to freezing
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作者 李方方 刘静 乐恺 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2009年第1期63-72,共10页
Analytically solving a three-dimensional (3-D) bioheat transfer problem with phase change during a freezing process is extremely difficult but theoretically important. The moving heat source model and the Green func... Analytically solving a three-dimensional (3-D) bioheat transfer problem with phase change during a freezing process is extremely difficult but theoretically important. The moving heat source model and the Green function method are introduced to deal with the cryopreservation process of in vitro biomaterials. Exact solutions for the 3-D temperature transients of tissues under various boundary conditions, such as totally convective cooling, totally fixed temperature cooling and a hybrid between them on tissue surfaces, are obtained. Furthermore, the cryosurgical process in living tissues subject to freezing by a single or multiple cryoprobes is also analytically solved. A closed-form analytical solution to the bioheat phase change process is derived by considering contributions from blood perfusion heat transfer, metabolic heat generation, and heat sink of a cryoprobe. The present method is expected to have significant value for analytically solving complex bioheat transfer problems with phase change. 展开更多
关键词 three-dimensional phase change heat transfer problem CRYOSURGERY CRYOPRESERVATION moving heat source model bioheat transfer Green's function analytical solution
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The dimension split element-free Galerkin method for three-dimensional potential problems 被引量:4
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作者 Z.J.Meng H.Cheng +1 位作者 L.D.Ma Y.M.Cheng 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2018年第3期462-474,共13页
This paper presents the dimension split element-free Galerkin (DSEFG) method for three-dimensional potential problems, and the corresponding formulae are obtained. The main idea of the DSEFG method is that a three-d... This paper presents the dimension split element-free Galerkin (DSEFG) method for three-dimensional potential problems, and the corresponding formulae are obtained. The main idea of the DSEFG method is that a three-dimensional potential problem can be transformed into a series of two-dimensional problems. For these two-dimensional problems, the improved moving least-squares (IMLS) approximation is applied to construct the shape function, which uses an orthogonal function system with a weight function as the basis functions. The Galerkin weak form is applied to obtain a discretized system equation, and the penalty method is employed to impose the essential boundary condition. The finite difference method is selected in the splitting direction. For the purposes of demonstration, some selected numerical examples are solved using the DSEFG method. The convergence study and error analysis of the DSEFG method are presented. The numerical examples show that the DSEFG method has greater computational precision and computational efficiency than the IEFG method. 展开更多
关键词 Dimension split method Improved moving least-squares (IMLS) approximation Improved element-free Galerkin (IEFG) method Finite difference method (FDM) Dimension split element-free Galerkin (DSEFG) method Potential problem
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