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A Temperature-Indexed Concrete Damage Plasticity Model Incorporating Bond-Slip Mechanism for Thermo-Mechanical Analysis of Reinforced Concrete Structures
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作者 Wu Feng Tengku Anita Raja Hussin Xu Yang 《Structural Durability & Health Monitoring》 2026年第1期216-234,共19页
This study investigates the thermo–mechanical behavior of C40 concrete and reinforced concrete subjected to elevated temperatures up to 700℃by integrating experimental testing and advanced numerical modeling.A tempe... This study investigates the thermo–mechanical behavior of C40 concrete and reinforced concrete subjected to elevated temperatures up to 700℃by integrating experimental testing and advanced numerical modeling.A temperature-indexed Concrete Damage Plasticity(CDP)framework incorporating bond–slip effects was developed in Abaqus to capture both global stress–strain responses and localized damage evolution.Uniaxial compression tests on thermally exposed cylinders provided residual strength data and failure observations for model calibration and validation.Results demonstrated a distinct two-stage degradation regime:moderate stiffness and strength reduction up to~400℃,followed by sharp deterioration beyond 500℃–600℃,with residual capacity at 700℃reduced to~20%–25%of the ambient value.Strain–damage analyses revealed the formation of a peripheral tensile strain band,which thickened and propagated inward with increasing temperature,governing crack initiation and cover spalling.Supplemental analyses highlighted that transverse reinforcement improved ductility and damage distribution at moderate temperatures(~300℃),but bond deterioration and steel softening beyond~600℃substantially diminished confinement effectiveness.The proposed CDP model accurately reproduced experimental stress–strain curves(R^(2)≈0.94–0.98 up to 600℃;≈0.90 at 700℃),with peak stress errors within 7%–10%and energy absorption captured within~12%.These findings confirm the robustness of the temperature-indexed CDP framework for simulating fire-damaged reinforced concrete and provide practical guidelines for post-fire assessment,spalling detection,and fire-resilient design of structural members. 展开更多
关键词 thermo-mechanical coupling high temperature concrete damage plasticity(CDP) BOND-SLIP residual strength fire resistance spalling prediction structural safety assessment
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COUPLED THERMO-MECHANICAL ANALYSIS OF FUNCTIONALLY GRADIENT WEAK/MICRO-DISCONTINUOUS INTERFACE WITH GRADED FINITE ELEMENT METHOD 被引量:2
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作者 Zhiwen Gao Kang Yong Lee Youhe Zhou 《Acta Mechanica Solida Sinica》 SCIE EI 2012年第4期331-341,共11页
Coupled thermo-mechanical analysis of two bonded functionally graded materials subjected to thermal loads is conducted in this study with the graded finite element method. The thermal-mechanical properties of the bi-m... Coupled thermo-mechanical analysis of two bonded functionally graded materials subjected to thermal loads is conducted in this study with the graded finite element method. The thermal-mechanical properties of the bi-material interfaces are classified based on discontinuity degrees of their material properties and their derivatives at the interfaces. Numerical results indicate that discontinuity exerts remarkable effect on the temperature profile and stress value at the interface of two bonded functionally-graded materials. Under the thermal flux loading conditions, the stronger the interface discontinuity is, the smaller the heat flux is. 展开更多
关键词 functionally graded material thermo-mechanical analysis weak/micro discontin-uous graded finite element method
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Thermo-mechanical analysis of an SI engine piston using different boundary condition treatments
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作者 Amir-Hasan Kakaee Javad Gharloghi +1 位作者 Aliasghar Foroughifar Abdoreza Khanlari 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第10期3817-3829,共13页
Heat transfer of an SI engine's piston is calculated by employing three different methods based on resistor-capacitor model with the help of MATLAB code, and then the piston is thermo-mechanically analyzed using c... Heat transfer of an SI engine's piston is calculated by employing three different methods based on resistor-capacitor model with the help of MATLAB code, and then the piston is thermo-mechanically analyzed using commercial ANSYS code. The results of three methods are compared to study their effects on the piston thermal behavior. It is shown that resistor-capacitor model with less number of equations and consequently less solution time, is an appropriate method for solving problems of engine piston heat transfer. In the second part, the thermal stresses due to non-uniform temperature distribution, and mechanical stresses due to mechanical loads are calculated. Finally, the temperature distributions as a thermal load along with mechanical loads are applied to the piston to determine the total stress distribution and critical fracture zones. It is found that the amount of thermal stresses is considerable. 展开更多
关键词 PISTON TEMPERATURE boundary condition STRESS thermo-mechanical analysis
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Design and Coupled Thermo-Mechanical Analysis of Silicon Carbide Primary Mirror Assembly
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作者 HAN Yuan-yuan ZHANG Yu-min HAN Jie-cai 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2006年第B12期62-65,共4页
Based on the principle that the thermal expansion coefficient of the support structure should match that of the mirror, three schemes of primary mirror assembly were designed. Of them, the first is fused silica mirror... Based on the principle that the thermal expansion coefficient of the support structure should match that of the mirror, three schemes of primary mirror assembly were designed. Of them, the first is fused silica mirror plus 4J32 flexible support plus ZTC4 support back plate, the second K9 mirror plus 4J45 flexible support plus ZTC4 support back plate, and the third SiC mirror plus SiC rigid support back plate. A coupled thermo-mechanical analysis of the three primary mirror assemblies was made with finite element method. The results show that the SiC assembly is the best of all schemes in terms of their combination properties due to its elimination of the thermal expansion mismatch between the materials. The analytical results on the cryogenic property of the SiC primary mirror assembly show a higher surface finish of the SiC mirror even under the cryogenic condition. 展开更多
关键词 silicon carbide primary mirror assembly DESIGN coupled thermo-mechanical analysis
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Transient thermo-mechanical analysis for bimorph soft robot based on thermally responsive liquid crystal elastomers 被引量:1
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作者 Yun CUI Yafei YIN +4 位作者 Chengjun WANG K. SIM Yuhang LI Cunjiang YU Jizhou SONG 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2019年第7期943-952,共10页
Thermally responsive liquid crystal elastomers (LCEs) hold great promise in applications of soft robots and actuators because of the induced size and shape change with temperature. Experiments have successfully demons... Thermally responsive liquid crystal elastomers (LCEs) hold great promise in applications of soft robots and actuators because of the induced size and shape change with temperature. Experiments have successfully demonstrated that the LCE based bimorphs can be effective soft robots once integrated with soft sensors and thermal actuators. Here, we present an analytical transient thermo-mechanical model for a bimorph structure based soft robot, which consists of a strip of LCE and a thermal inert polymer actuated by an ultra-thin stretchable open-mesh shaped heater to mimic the unique locomotion behaviors of an inchworm. The coupled mechanical and thermal analysis based on the thermo-mechanical theory is carried out to underpin the transient bending behavior, and a systematic understanding is therefore achieved. The key analytical results reveal that the thickness and the modulus ratio of the LCE and the inert polymer layer dominate the transient bending deformation. The analytical results will not only render fundamental understanding of the actuation of bimorph structures, but also facilitate the rational design of soft robotics. 展开更多
关键词 TRANSIENT thermo-mechanical analysis SOFT ROBOT thermal-responsive liq- UID crystal elastomer (LCE)
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Thermo-Mechanical Analysis of a Typical Vehicle Engine Using PTC-Creo
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作者 Jafar Mahmoudi 《Journal of Mechanical Materials and Mechanics Research》 2022年第2期1-15,共15页
In this work,a typical vehicle engine is modeled within PTC-Creo soft­ware,and its thermal,mechanical,and thermo-mechanical performance are evaluated.This is followed by the vibrational,fatigue,and buckling analy... In this work,a typical vehicle engine is modeled within PTC-Creo soft­ware,and its thermal,mechanical,and thermo-mechanical performance are evaluated.This is followed by the vibrational,fatigue,and buckling analy­sis of the assembly of components,which are the predominant failure caus­es.The results show that the least temperature gradient occurs in the center of the pin,which connects the piston to the connecting rod,the maximum displacement is seen just below the piston head,and the thermo-mechanical failure is caused mostly(about 85%)by the mechanical load rather than the thermal one.Also,in fatigue analysis,the minimum and maximum values for the safety factor are 0.63 and 5,respectively.The results can prevent the reoccurrence of similar failures and help the enhancement of the compo­nents’design and manufacturing process. 展开更多
关键词 Stress analysis Engine failure PTC-Creo Thermomechanical analysis
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Thermo-Mechanical Analysis of Water-Cooled Gun Barrel During Burst Firing 被引量:1
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作者 樊黎霞 胡志刚 赵建波 《Defence Technology(防务技术)》 SCIE EI CAS 2006年第1期1-6,共6页
The thermo-mechanical stress and deformation of water-cooled gun barrel during burst firing are studied by finite element analysis (FEA). The problem is modeled in two steps: 1) A transient heat transfer analysis is f... The thermo-mechanical stress and deformation of water-cooled gun barrel during burst firing are studied by finite element analysis (FEA). The problem is modeled in two steps: 1) A transient heat transfer analysis is first carried out in order to determine temperature evolution and to predict the residual temperatures during the burst firing event; 2) The thermo-mecha- nical stresses and deformation caused by both the residual temperature field and the gas pressure are then calculated. The results show that the residual temperature field tends to a steady state with the increasing of rounds. The residual temperature field has much effect on the gun barrel stress and deformation, especially on the assembly area between barrel and water jacket. The gage between the barrel and water jacket is the critical factor to the thermo- mechanical stress and deformation. The results of this analysis will be very useful to develop the new strength design theory of the liquid-cooled gun barrel. 展开更多
关键词 有限元分析 机械分析 武器
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Changes in border-associated macrophages after stroke: Single-cell sequencing analysis 被引量:2
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作者 Ning Yu Yang Zhao +3 位作者 Peng Wang Fuqiang Zhang Cuili Wen Shilei Wang 《Neural Regeneration Research》 2026年第1期346-356,共11页
Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macro... Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macrophages have been poorly understood and largely overlooked. However, a recent study reported that border-associated macrophages participate in stroke-induced inflammation, although many details and the underlying mechanisms remain unclear. In this study, we performed a comprehensive single-cell analysis of mouse border-associated macrophages using sequencing data obtained from the Gene Expression Omnibus(GEO) database(GSE174574 and GSE225948). Differentially expressed genes were identified, and enrichment analysis was performed to identify the transcription profile of border-associated macrophages. CellChat analysis was conducted to determine the cell communication network of border-associated macrophages. Transcription factors were predicted using the ‘pySCENIC' tool. We found that, in response to hypoxia, borderassociated macrophages underwent dynamic transcriptional changes and participated in the regulation of inflammatory-related pathways. Notably, the tumor necrosis factor pathway was activated by border-associated macrophages following ischemic stroke. The pySCENIC analysis indicated that the activity of signal transducer and activator of transcription 3(Stat3) was obviously upregulated in stroke, suggesting that Stat3 inhibition may be a promising strategy for treating border-associated macrophages-induced neuroinflammation. Finally, we constructed an animal model to investigate the effects of border-associated macrophages depletion following a stroke. Treatment with liposomes containing clodronate significantly reduced infarct volume in the animals and improved neurological scores compared with untreated animals. Taken together, our results demonstrate comprehensive changes in border-associated macrophages following a stroke, providing a theoretical basis for targeting border-associated macrophages-induced neuroinflammation in stroke treatment. 展开更多
关键词 border-associated macrophages CLODRONATE hypoxia ISCHEMIA-REPERFUSION ischemic stroke liposomes neuroinflammation single-cell sequencing analysis STAT3 tumor necrosis factor
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Thermo-mechanical damage behavior of the interface between hybrid alkali-resistant glass fiber-reinforced concrete and rock under high and variable temperature conditions
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作者 Cong Zhang Zhen Xu +4 位作者 Shanyong Wang Chong Shi Hui Wang Yonggang Zhang Guoqing Chen 《International Journal of Mining Science and Technology》 2026年第2期399-421,共23页
Thermal-mechanical damage and deformation at the interface between shotcrete linings and the surrounding rock of tunnels under high-temperature and variable-temperature conditions are critical to the safe construction... Thermal-mechanical damage and deformation at the interface between shotcrete linings and the surrounding rock of tunnels under high-temperature and variable-temperature conditions are critical to the safe construction and operation of tunnel engineering.This study investigated the thermo-mechanical damage behavior of the composite interface between alkali-resistant glass fiber-reinforced concrete(ARGFRC)and granite,focusing on a plateau railway tunnel.Laboratory triaxial tests,laser scanning,XRD analysis,numerical simulations,and theoretical analyses were employed to investigate how different initial curing temperatures and joint roughness coefficient(JRC)influence interfacial damage behavior.The results indicate that an increase in interface roughness exacerbates the structural damage at the interface.At a JRC of 19.9 and a temperature of 70℃,crack initiation in granite was notably restrained when the confining pressure rose from 7 MPa to 10 MPa.Roughness-induced stress distribution at the interface was notably altered,although this effect became less pronounced under high confining pressure conditions.Additionally,during high-temperature curing,thermal stress concentration at the tips of micro-convex protrusions on the granite surface induced microcracks in the adjacent ARGFRC matrix,followed by deformation.These findings provide practical guidelines for designing concrete support systems to ensure tunnel structural safety in high-altitude regions with harsh thermal environments. 展开更多
关键词 High and variable temperature ARGFRC-granite INTERFACE thermo-mechanical coupling Damage evolution
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Crystal structure,thermal analysis,and luminescence properties of six heterocyclic lanthanide complexes
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作者 SONG Zihe ZHAO Jinjin +1 位作者 REN Ning ZHANG Jianjun 《无机化学学报》 北大核心 2026年第1期181-192,共12页
Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'... Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'-bipyridine]were successfully synthesized by the volatilization of the solution at room temperature.The crystal structures of six complexes were determined by single-crystal X-ray diffraction technology.The results showed that the complexes all have a binuclear structure,and the structures contain free ethanol molecules.Moreover,the coordination number of the central metal of each structural unit is eight.Adjacent structural units interact with each other through hydrogen bonds and further expand to form 1D chain-like and 2D planar structures.After conducting a systematic study on the luminescence properties of complexes 1-4,their emission and excitation spectra were obtained.Experimental results indicated that the fluorescence lifetimes of complexes 2 and 3 were 0.807 and 0.845 ms,respectively.The emission spectral data of complexes 1-4 were imported into the CIE chromaticity coordinate system,and their corre sponding luminescent regions cover the yellow light,red light,green light,and orange-red light bands,respectively.Within the temperature range of 299.15-1300 K,the thermal decomposition processes of the six complexes were comprehensively analyzed by using TG-DSC/FTIR/MS technology.The hypothesis of the gradual loss of ligand groups during the decomposition process was verified by detecting the escaped gas,3D infrared spectroscopy,and ion fragment information detected by mass spectrometry.The specific decomposition path is as follows:firstly,free ethanol molecules and neutral ligands are removed,and finally,acidic ligands are released;the final product is the corresponding metal oxide.CCDC:2430420,1;2430422,2;2430419,3;2430424,4;2430421,5;2430423,6. 展开更多
关键词 lanthanide complexes fluorescence property crystal structure thermal analysis
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Cavity ring-down spectroscopy CO gas sensor integrating principal component analysis with savitzky-golay filtering
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作者 GUO Zi-long SHI Cheng-rui +4 位作者 DONG Yuan-yuan ZHANG Lei SUN Xiao-yuan SUN Jing-jing ZHOU Sheng 《中国光学(中英文)》 北大核心 2026年第1期179-189,共11页
The Savitzky-Golay(SG)filter,which employs polynomial least-squares approximations to smooth data and estimate derivatives,is widely used for processing noisy data.However,noise suppression by the SG filter is recogni... The Savitzky-Golay(SG)filter,which employs polynomial least-squares approximations to smooth data and estimate derivatives,is widely used for processing noisy data.However,noise suppression by the SG filter is recognized to be limited at data boundaries and high frequencies,which can significantly reduce the signal-to-noise ratio(SNR).To solve this problem,a novel method synergistically integrating Principal Component Analysis(PCA)with SG filtering is proposed in this paper.This approach avoids the is-sue of excessive smoothing associated with larger window sizes.The proposed PCA-SG filtering algorithm was applied to a CO gas sensing system based on Cavity Ring-Down Spectroscopy(CRDS).The perform-ance of the PCA-SG filtering algorithm is demonstrated through comparison with Moving Average Filtering(MAF),Wavelet Transformation(WT),Kalman Filtering(KF),and the SG filter.The results demonstrate that the proposed algorithm exhibits superior noise reduction capabilities compared to the other algorithms evaluated.The SNR of the ring-down signal was improved from 11.8612 dB to 29.0913 dB,and the stand-ard deviation of the extracted ring-down time constant was reduced from 0.037μs to 0.018μs.These results confirm that the proposed PCA-SG filtering algorithm effectively improves the smoothness of the ring-down curve data,demonstrating its feasibility. 展开更多
关键词 cavity ring-down spectroscopy CO gas sensor principal component analysis Savitzky-Golay filter
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Global,regional,and national burdens of acute respiratory infections among children and adolescents from 1990 to 2021:A systematic analysis
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作者 Xiang Meng Sijie Li +4 位作者 Meiyan Li Husheng Xiong Xuejuan Chen Yonghui Zhong Dingmei Zhang 《Asian Pacific Journal of Tropical Medicine》 2026年第2期51-60,I0001-I0061,共71页
Objective:To evaluate the global,regional,and national burden and determinants of Acute Respiratory Infections(ARIs)among children and adolescents from 1990 to 2021.Methods:We analysed ARI mortality and disability-adj... Objective:To evaluate the global,regional,and national burden and determinants of Acute Respiratory Infections(ARIs)among children and adolescents from 1990 to 2021.Methods:We analysed ARI mortality and disability-adjusted life years(DALYs),stratified by age,sex,and economic development level based on data retrieved from the Global Burden of Disease study 2021.Decomposition and frontier analyses were employed to identify key drivers of burden variation and visualize potential reductions based on development levels.Results:Between 1990 and 2021,the global burden of ARIs showed a significant decline in both achievable age-standardized DALYs rate and age-standardized mortality rates(EAPC=-3.87 and-3.81,respectively).Different age groups and sex witnessed different levels of ARI burden,males experienced heavier burden than females and the 0-4 years-old group experienced heavier burden than other study age groups.Most of the 204 countries and territories experienced a downward trend of ARI burden,with slight increases observed only in Lesotho and Dominica.A negative correlation was found between the Socio-demographic Index and ARI burden.Decomposition analysis indicated that the significant decreases in deaths and DALYs were primarily driven by epidemiological changes.Conclusions:The global burden of ARIs among children and adolescents has declined over the past three decades,but substantial regional disparities persist.Targeted public health strategies are needed to address the continued ARI burden in high-risk regions and vulnerable age groups. 展开更多
关键词 Respiratory infection Global disease burden Decomposition analysis Frontier analysis
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Artificial intelligence-assisted non-metallic inclusion particle analysis in advanced steels using machine learning:A review
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作者 Gonghao Lian Xiaoming Liu +3 位作者 Qiang Wang Chunguang Shen Yi Wang Wangzhong Mu 《International Journal of Minerals,Metallurgy and Materials》 2026年第2期401-416,共16页
The detection and characterization of non-metallic inclusions are essential for clean steel production.Recently,imaging analysis combined with high-dimensional data processing of metallic materials using artificial in... The detection and characterization of non-metallic inclusions are essential for clean steel production.Recently,imaging analysis combined with high-dimensional data processing of metallic materials using artificial intelligence(AI)-based machine learning(ML)has developed rapidly.This technique has achieved impressive results in the field of inclusion classification in process metallurgy.The present study surveys the ML modeling of inclusion prediction in advanced steels,including the detection,classification,and feature prediction of inclusions in different steel grades.Studies on clean steel with different features based on data and image analysis via ML are summarized.Regarding the data analysis,the inclusion prediction methodology based on ML establishes a connection between the experimental parameters and inclusion characteristics and analyzes the importance of the experimental parameters.Regarding the image analysis,the focus is placed on the classification of different types of inclusions via deep learning,in comparison with data analysis.Finally,further development of inclusion analyses using ML-based methods is recommended.This work paves the way for the application of AIbased methodologies for ultraclean-steel studies from a sustainable metallurgy perspective. 展开更多
关键词 machine learning inclusion classification image analysis data analysis clean steel
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Integrated transcriptome and metabolome analysis reveals light induction of anthocyanin rapid accumulation in red-fleshed peach after pre-harvest bagging
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作者 Jia Wei Fengjie He +6 位作者 Kexin Sun Li Wang Yiming Yin Junbei Ni Songling Bai Yuanwen Teng Huijuan Jia 《Horticultural Plant Journal》 2026年第3期539-554,共16页
Red-fleshed fruits are valued for their vibrant color and high anthocyanin content.Pre-harvest fruit bagging enhances fruit peel pigmentation,but its effect on flesh coloration remains poorly characterized.This study ... Red-fleshed fruits are valued for their vibrant color and high anthocyanin content.Pre-harvest fruit bagging enhances fruit peel pigmentation,but its effect on flesh coloration remains poorly characterized.This study revealed that removing bags from‘Gengcunyangtao’red-fleshed peach fruits triggers the rapid and uniform accumulation of anthocyanins in the flesh,resulting in anthocyanin levels that exceed those in unbagged fruits.The exposure to light after bag removal triggered significant increases in anthocyanin levels within 24 h.This was accompanied by the rapid upregulation of light-responsive and flavonoid biosynthetic gene expression levels within 6 h.A metabolomic analysis indicated that anthocyanin precursors,especially p-coumaric acid,accumulated before bag removal,thereby increasing substrate availability for rapid anthocyanin synthesis.On the basis of a weighted gene co-expression network analysis,MYB transcription factors,anthocyanin transporters,glutathione S-transferase,and multidrug and toxic compound extrusion(MATE)were identified as key regulators that coordinate precursor storage along with light-induced transcriptional activation.Notably,PpMYB4 binds to the promoter of PpGSTF14 and activates its expression,thereby promoting anthocyanin accumulation.The study findings elucidated the temporal coordination of metabolic priming and light-responsive transcriptional regulation driving rapid anthocyanin biosynthesis,with possible implications for improving peach fruit flesh coloration. 展开更多
关键词 Red-fleshed peach ANTHOCYANIN Pre-harvest fruit bagging Light exposure Transcriptome analysis Metabolome analysis
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Cloning and Bioinformatics Analysis of DsCBL4 Gene from Dianthus spiculifolius Schur
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作者 Di Haoyang Hou Xinyang +4 位作者 Li Yan You Xue Yu Yuxin Wang Jingang Zhang Haizhen 《Journal of Northeast Agricultural University(English Edition)》 2026年第1期22-34,共13页
Dianthus spiculifolius Schur,as an emerging ornamental plant,has extensive applications and economic values.In this study,the DsCBL4 gene was successfully cloned,and its tissue-specific expression,expression patterns ... Dianthus spiculifolius Schur,as an emerging ornamental plant,has extensive applications and economic values.In this study,the DsCBL4 gene was successfully cloned,and its tissue-specific expression,expression patterns under various abiotic stresses,subcellular localization,and bioinformatics analysis of the encoded amino acid sequence were conducted.The results showed that the coding region of the DsCBL4 gene was 675 bp long,encoding 224 amino acids.It had high homology with the amino acids encoded by Amaranthus tricolor,Chenopodium quinoa and Spinacia oleracea.The predicted relative molecular mass of DsCBL4 was 25.61 ku,with an isoelectric point of 4.58,and it had phosphorylation sites,belonging to an unstable hydrophilic protein.Its secondary structure includedα-helices,irregular coils and extended chains.The tertiary structure prediction revealed that DsCBL4 had four EFhand calcium-binding domains necessary for Ca2+binding in plant calmodulin-like proteins and the FPSF motif for calcineurin B-like protein(CBL)-interacting protein kinase(CIPK)activation.The expression level of the DsCBL4 gene showed tissue specificity,with the highest expression in roots.It was induced by drought,low temperature,combined drought and low temperature,salt stress,nitrogen stress,phosphorus stress,calcium ion stress,high temperature stress,and abscisic acid(ABA)stress.Both transient infection in Nicotiana tabacum L.and stable expression in transgenic Arabidopsis thaliana showed that the DsCBL4 protein was localized to the cell membrane.These results suggested that DsCBL4 might be involved in the abiotic stress response of Dianthus spiculifolius through the calcium signaling pathway,providing a theoretical basis for understanding its molecular mechanism.This study provided an important reference for further exploring the role of the DsCBLs gene family in plant stress resistance. 展开更多
关键词 Dianthus spiculifolius Schur CBL4 gene gene cloning expression analysis structural analysis
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Comprehensive pan-cancer analysis of the receptor-interacting protein kinase family expression,genomic alterations,and functional implications
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作者 Wan-Rong Li Xin Li Jian Wang 《Life Research》 2026年第1期35-44,共10页
Background:Receptor-interacting protein kinases(RIPKs)regulate cell death,inflammation,and immune responses,yet their roles in cancer are not fully understood.This study investigates the expression,genomic alterations... Background:Receptor-interacting protein kinases(RIPKs)regulate cell death,inflammation,and immune responses,yet their roles in cancer are not fully understood.This study investigates the expression,genomic alterations,and functional implications of RIPK family members across various cancers.Methods:We collected multi-omics data from The Cancer Genome Atlas and other public databases,including gene expression,copy number variation(CNV),mutation,methylation,tumor mutation burden(TMB),and microsatellite instability(MSI).Differential expression and survival analyses were performed using DESeq2 and Cox proportional hazards models.CNV and mutation data were analyzed with GISTIC2 and Mutect2,and methylation data with the ChAMP package.Correlations with TMB and MSI were assessed using Pearson coefficients,and gene set enrichment analysis was conducted with the MSigDB Hallmark gene sets.Results:RIPK family members show significant differential expression in various cancers,with RIPK1 and RIPK4 frequently altered.Survival analysis reveals heterogeneous impacts on overall survival.CNV and mutation analyses identify high alteration frequencies for RIPK2 and RIPK7,affecting gene expression.RIPK1 and RIPK7 are hypermethylated in several cancers,inversely correlating with RIPK3 expression.RIPK1,RIPK2,RIPK5,RIPK6,and RIPK7 correlate positively with TMB,while RIPK3 shows negative correlations in some cancers.MSI analysis indicates associations with DNA mismatch repair.G ene set enrichment analysis highlights immune-related pathway enrichment for RIPK1,RIPK2,RIPK3,and RIPK6,and cell proliferation and DNA repair pathways for RIPK4 and RIPK5.RIPK family members showed heterogeneous alterations across cancers:for example,RIPK7 was mutated in up to~15%of u terine c orpus e ndometrial c arcinoma and l ung s quamous c ell c arcinoma cases,and RIPK1 and RIPK7 exhibited frequent promoter hypermethylation in multiple tumor types.Several genes displayed context-dependent associations with overall survival and with TMB/MSI.Conclusion:This pan-cancer analysis of the RIPK family reveals their diverse roles and potential as biomarkers and therapeutic targets.The findings emphasize the importance of RIPK genes in tumorigenesis and suggest context-dependent functions across cancer types.Further studies are needed to explore their mechanisms in cancer development and clinical applications. 展开更多
关键词 RIPK family pan-cancer analysis tumor mutation burden microsatellite instability gene set enrichment analysis
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Motion Performance Analysis of Offshore Lifting for Wind-Fishery Integrated Aquaculture Net Cage Considering Multi-Body Coupling Effects
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作者 WANG Wanqi YU Tongshun +2 位作者 LU Peng ZHAO Hui TAO Wei 《南方能源建设》 2026年第1期1-15,共15页
[Objective]This study aims to investigate the multi-body hydrodynamic interaction mechanisms during offshore lifting operations of aquaculture net cages in wind-fishery integration systems.By integrating numerical sim... [Objective]This study aims to investigate the multi-body hydrodynamic interaction mechanisms during offshore lifting operations of aquaculture net cages in wind-fishery integration systems.By integrating numerical simulations and dynamic analysis methods,this study systematically investigates the coupled dynamic response characteristics during the cage-carrier vessel separation process to reveal its dynamic evolution patterns and key influence mechanisms.[Method]Based on potential flow theory,a fully coupled dynamic analysis model of crane vessel-net cage-semi-submersible barge was established for a marine ranch project in Guangdong.The complete lifting process was dynamically simulated using SESAM software.Five typical operating sea states were configured to investigate the influence of wave parameters on the system's motion response under combined wave-current-wind actions.[Result]The results demonstrate that wave period dominates the system stability.Under short-period conditions,the system maintains stable motion with relatively small horizontal relative displacements,while long-period conditions excite low-frequency resonance,leading to significant slow-drift motions.Vertical response analysis reveals that long-period waves cause severe relative displacement fluctuations between the cage and semi-submersible vessel,with actual displacement amplitudes doubling the preset safety target of 2.045 m.Quantitative analysis further indicates that when significant wave height increases from 1.0 m to 1.5 m,the actual displacement amplitude increases by approximately 20%relative to the target displacement of 2.045 m,demonstrating that its influence is significantly weaker than the displacement variations induced by wave period changes.The complete dynamic simulation successfully captures the continuous dynamic response characteristics during the lifting process.[Conclusion]This research clarifies the influence mechanisms of wave parameters on the cage lifting process,identifying wave period as the crucial factor for operational safety.An operation window assessment method incorporating multi-body coupling effects is established,proposing a safety criterion with peak period not exceeding six seconds as the core requirement.The findings provide theoretical foundation for safe installation of marine ranch net cages and offer valuable references for similar offshore lifting operations. 展开更多
关键词 wind-fishery integration offshore lifting hydrodynamic analysis multi-body coupling analysis motion response safe operation window
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Corrigendum to“Transcriptomic and biochemical analysis of the mechanism of sodium gluconate promoting the degradation of benzo[a]pyrene by Bacillus subtilis MSC4”[Journal of Environmental Sciences,Volume 152,June 2025,Pages 39-53]
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《Journal of Environmental Sciences》 2026年第2期789-791,共3页
Rui Chena,b,Tangbing Cui a,b,∗a School of Biology and Biological Engineering,South China University of Technology,Guangzhou 510006,China b Guangdong Key Laboratory of Fermentation and Enzyme Engineering,South China Un... Rui Chena,b,Tangbing Cui a,b,∗a School of Biology and Biological Engineering,South China University of Technology,Guangzhou 510006,China b Guangdong Key Laboratory of Fermentation and Enzyme Engineering,South China University of Technology,Guangzhou 510006,China The authors regret that the published version of this article contained several errors and omissions,which are described and corrected below.1.Figs.3 and 4(figure order and legends).In the published article,Figs.3 and 4 were inadvertently published in reversed order.The figures should be swapped so that the figure content matches its caption.The correct figures and their legends are provided on the following page.2.Title correction.The compound name in the published title was incorrectly typeset as“benzo[a]pyrene”The correct spelling is“benzo[a]pyrene.”3.Text corrections in Section 2.4.Several typographical errors occurred in Section 2.4(“Up-regulation of acetoin,lactate,and kanosamine biosynthesis under sodium gluconate treatment”). 展开更多
关键词 benzo pyrene degradation correction transcriptomic analysis biochemical analysis CORRIGENDUM sodium gluconate Bacillus subtilis Msc enzyme engineeringsouth
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Correction:Uncertainty and sensibility analysis of loss-of-forced-cooling accidents for 150-MWt molten salt reactors
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作者 Kai Wang Chao-Qun Wang +2 位作者 Qun Yang Zhao-Zhong He Na-Xiu Wang 《Nuclear Science and Techniques》 2026年第5期394-394,共1页
Correction to:Nuclear Science and Techniques(2025)36:111 https://doi.org/10.1007/s41365-025-01681-9.In the sentence beginning‘The weights of the parameters used for the…’in this article,the text‘RCSs’should have ... Correction to:Nuclear Science and Techniques(2025)36:111 https://doi.org/10.1007/s41365-025-01681-9.In the sentence beginning‘The weights of the parameters used for the…’in this article,the text‘RCSs’should have read‘SCRs’.In Table 7 of this article,the column header ρ_fuel was incorrect and should have read CPv_fuel.For completeness and transparency,the old incorrect version and the corrected version of Table 7 are displayed below. 展开更多
关键词 uncertainty analysis molten salt reactors loss forced cooling accidents nuclear science techniques weights parameters sensitivity analysis
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Advanced isoconversional kinetic analysis of lepidolite sulfation product decomposition reactions for selectively extracting lithium
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作者 Yubo Liu Baozhong Ma +4 位作者 Jiahui Cheng Xiang Li Hui Yang Chengyan Wang Yongqiang Chen 《International Journal of Minerals,Metallurgy and Materials》 2026年第1期217-227,共11页
The sulfation and decomposition process has proven effective in selectively extracting lithium from lepidolite.It is essential to clarify the thermochemical behavior and kinetic parameters of decomposition reactions.A... The sulfation and decomposition process has proven effective in selectively extracting lithium from lepidolite.It is essential to clarify the thermochemical behavior and kinetic parameters of decomposition reactions.Accordingly,comprehensive kinetic study by employing thermalgravimetric analysis at various heating rates was presented in this paper.Two main weight loss regions were observed during heating.The initial region corresponded to the dehydration of crystal water,whereas the subsequent region with overlapping peaks involved complex decomposition reactions.The overlapping peaks were separated into two individual reaction peaks and the activation energy of each peak was calculated using isoconversional kinetics methods.The activation energy of peak 1 exhibited a continual increase as the reaction conversion progressed,while that of peak 2 steadily decreased.The optimal kinetic models,identified as belonging to the random nucleation and subsequent growth category,provided valuable insights into the mechanism of the decomposition reactions.Furthermore,the adjustment factor was introduced to reconstruct the kinetic mechanism models,and the reconstructed models described the kinetic mechanism model more accurately for the decomposition reactions.This study enhanced the understanding of the thermochemical behavior and kinetic parameters of the lepidolite sulfation product decomposition reactions,further providing theoretical basis for promoting the selective extraction of lithium. 展开更多
关键词 LITHIUM LEPIDOLITE decomposition reactions KINETICS isoconversional analysis
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