Background and Objectives:Stunting is a global health challenge,especially in developing countries like Indonesia,where its prevalence reached 21.6%in 2022.This condition stems from malnutrition,recurrent infections,a...Background and Objectives:Stunting is a global health challenge,especially in developing countries like Indonesia,where its prevalence reached 21.6%in 2022.This condition stems from malnutrition,recurrent infections,and inadequate care during the first 1,000 days of life.Maternal nutrition is critical for fetal growth,as deficiencies can lead to low birth weight and short birth length,increasing the risk of stunting.This study evaluates the potential of fortified tempeh as a nutritional intervention to improve birth outcomes.Methods and Study Design:A quasi-experimental study with a quantitative approach was conducted to compare the effects of regular and fortified tempeh on BW and BL among pregnant women in Kuningan Regency.展开更多
Objective:To highlight the comparative studies between total isoflavone extracts from soybean and tempeh on the neuronal oxidative stress and antioxidant activities.Methods:The total isoflavones were administered oral...Objective:To highlight the comparative studies between total isoflavone extracts from soybean and tempeh on the neuronal oxidative stress and antioxidant activities.Methods:The total isoflavones were administered orally for 15 days with 3 selected doses(10,20 and 40 mg/kg).Piracetam(400 mg/kg,p.o.)was used as a standard drug while scopolamine(1 mg/kg,i.p.)was used as a drug that promoted amnesia in selected groups.The oxidative markers(thiobarbituric acid reactive substances and nitric oxide)were measured in brain homogenate.The antioxidant activities evaluated were catalase,superoxide dismutase,glutathione reductase and glutathione.Results:Our results showed that soybean and tempeh isoflavones significantly improved the levels of catalase,superoxide dismutase,glutathione reductase and glutathione while decreased levels of thiobarbituric acid reactive substances and nitric oxide in both the brain of normal as well as scopolamine-induced animals.Conclusions:Our findings suggested that soybean and tempeh isoflavones could be useful in the management and prevention of age-related neurodegenerative changes including Alzheimer’s disease through its antioxidant activities.展开更多
基金the Culinary Laboratory,Faculty of Public Health,Hasanuddin University.
文摘Background and Objectives:Stunting is a global health challenge,especially in developing countries like Indonesia,where its prevalence reached 21.6%in 2022.This condition stems from malnutrition,recurrent infections,and inadequate care during the first 1,000 days of life.Maternal nutrition is critical for fetal growth,as deficiencies can lead to low birth weight and short birth length,increasing the risk of stunting.This study evaluates the potential of fortified tempeh as a nutritional intervention to improve birth outcomes.Methods and Study Design:A quasi-experimental study with a quantitative approach was conducted to compare the effects of regular and fortified tempeh on BW and BL among pregnant women in Kuningan Regency.
基金supported by the Research Excellence Funds(600-RMI/DANA 5/3/REI(3/2013)and 600-RMI/ST/DANA 5/3/DST(465/2011)),Research Management Centure,Universiti Teknologi MARA,Malaysia and Institute of Graduate Studies,Universiti Teknologi MARA,Malaysia
文摘Objective:To highlight the comparative studies between total isoflavone extracts from soybean and tempeh on the neuronal oxidative stress and antioxidant activities.Methods:The total isoflavones were administered orally for 15 days with 3 selected doses(10,20 and 40 mg/kg).Piracetam(400 mg/kg,p.o.)was used as a standard drug while scopolamine(1 mg/kg,i.p.)was used as a drug that promoted amnesia in selected groups.The oxidative markers(thiobarbituric acid reactive substances and nitric oxide)were measured in brain homogenate.The antioxidant activities evaluated were catalase,superoxide dismutase,glutathione reductase and glutathione.Results:Our results showed that soybean and tempeh isoflavones significantly improved the levels of catalase,superoxide dismutase,glutathione reductase and glutathione while decreased levels of thiobarbituric acid reactive substances and nitric oxide in both the brain of normal as well as scopolamine-induced animals.Conclusions:Our findings suggested that soybean and tempeh isoflavones could be useful in the management and prevention of age-related neurodegenerative changes including Alzheimer’s disease through its antioxidant activities.
