目的探讨超声心动图检测Tei指数对孕中晚期子痫前期孕妇胎儿心脏功能及出生情况的影响。方法选取2022年1月—2023年10月江西省妇幼保健院收治的重度子痫前期孕妇40例作为A组,轻度子痫前期孕妇50例作为B组,选取2022年1月—2023年10月同...目的探讨超声心动图检测Tei指数对孕中晚期子痫前期孕妇胎儿心脏功能及出生情况的影响。方法选取2022年1月—2023年10月江西省妇幼保健院收治的重度子痫前期孕妇40例作为A组,轻度子痫前期孕妇50例作为B组,选取2022年1月—2023年10月同期正常孕妇35例作为C组。所有孕妇均予以超声心动图检查,比较3组孕妇新生儿心室Tei指数、心室功能指标及出生情况,采用Pearson相关性分析孕中晚期子痫前期孕妇胎儿心室Tei指数与胎儿出生情况的关系。结果与C组比较(0.25±0.02,0.28±0.02),A组和B组左室Tei指数(0.47±0.03,0.34±0.01)以及右室Tei指数(0.53±0.02,0.37±0.03)均显著上升(P<0.05),与B组比较(0.34±0.01,0.37±0.03),A组左室Tei指数(0.47±0.03)和右室Tei指数(0.53±0.02)均显著上升(P<0.05)。3组左室Tei指数和右室Tei指数比较差异有统计学意义(P<0.05)。与C组比较(64.01±8.94 ms,169.02±7.72 ms,67.44±9.76 ms,172.33±7.30 ms),A组左心室等容时间(71.25±9.80)ms及右心室等容时间(78.25±11.89)ms显著上升,左心室射血时间(162.21±5.36)ms及右心室射血时间(165.24±6.58)ms显著下降;B组右心室等容时间(74.20±10.34)ms显著上升,右心室射血时间(167.83±8.33)ms显著下降(P<0.05)。与B组比较(165.65±6.87)ms,A组左心室射血时间(162.21±5.36)ms显著下降(P<0.05)。3组心室功能指标比较差异有统计学意义(P<0.05)。与C组比较(9.21±0.05分,9.99±0.06分),A组与B组孕妇新生儿出生孕周1min Apgar评分(8.47±1.25分,9.05±0.08分)及5 min Apgar评分(9.83±0.33分,9.95±0.29分)均显著下降(P<0.05),此外,A组孕妇新生儿出生体重(2230.28±536.96)g也显著下降(P<0.05)。与B组比较(3125.37±398.54 g,37.61±1.04周,9.05±0.08分),A组新生儿出生体重(2230.28±536.96)g、出生孕周(34.53±2.14)周、1 min Apgar评分(8.47±1.25)分显著下降(P<0.05)。3组孕妇新生儿出生情况比较差异有统计学意义(P<0.05)。孕中晚期子痫前期孕妇胎儿右心室Tei指数与出生体重、出生孕周、1 min Apgar评分及5 min Apgar评分呈负相关(r=-0.528,-0.385,-0.763,-0.572,均P<0.05)。结论孕中晚期子痫前期胎儿Tei指数与孕妇疾病程度相关,且以右心室出现损伤为主,此外Tei指数与胎儿出生时Apgar评分、孕周及体重相关,有望成为预测胎儿出生情况的一个指标。展开更多
Lead-free halide perovskites provide a promising solution for efficient thermoelectric materials due to their ultralow lattice thermal conductivity(κ_(L)).However,disadvantages such as the electrically resistive natu...Lead-free halide perovskites provide a promising solution for efficient thermoelectric materials due to their ultralow lattice thermal conductivity(κ_(L)).However,disadvantages such as the electrically resistive nature strongly affect their power factor.In this work,we introduced the Te-based halide perovskites thermoelectric material Cs_(2)TeI_(6),which is already known as a promising candidate for photovoltaic applications due to its moderate band gap.Our findings reveal that Cs_(2)TeI_(6)has an exceptionally ultralow κ_(L)at room temperature,reaching as low as 0.17 W·m^(-1)·K^(-1).We found that the four-phonon scattering processes play a dominant role in suppressing the thermal transport,leading to an approximate 50% reduction in its particle-like thermal conductivity κ_(p) at 300 K.The ultralow κ_(L)can be mainly attributed to the strong discrepancy in bonding strength,which induces large anharmonicity.The flat and dense phonon dispersions result in a strong phonon scattering rate,making it easy to generate wavelike phonon tunneling.After accounting for the wavelike thermal conductivity κ_(c),a nonstandard T^(-0.30)temperature dependence was observed.Benefiting from the ultralow κ_(L),n-type Cs_(2)TeI_(6)is predicted to achieve an extraordinary ZT of 2.26 at 700 K.This work highlights a pathway for searching high-performance and low-cost thermoelectrics based on lead-free halide perovskites.展开更多
目的探讨双多普勒Tei指数(DD-Tei指数)评估肺动脉高压新生儿肺动脉压力及右心功能的应用价值。方法选取2020年7月—2021年6月在厦门市儿童医院住院的矫正胎龄28~40周肺动脉高压新生儿90例(肺动脉高压组),按肺动脉压力分为轻度(40~50 mm ...目的探讨双多普勒Tei指数(DD-Tei指数)评估肺动脉高压新生儿肺动脉压力及右心功能的应用价值。方法选取2020年7月—2021年6月在厦门市儿童医院住院的矫正胎龄28~40周肺动脉高压新生儿90例(肺动脉高压组),按肺动脉压力分为轻度(40~50 mm Hg)、中度(51~70 mm Hg)、重度(>70 mm Hg)3组,其中轻度组35例,中度组30例,重度组25例。另选择同期同孕龄、无肺动脉高压新生儿30例为对照组。测量右心室面积变化分数(RVFAC)、三尖瓣环收缩期峰值位移(TAPSE)、三尖瓣环峰值速度(TAPSV)、DD-Tei指数。绘制受试者工作特征(ROC)曲线,评价右心功能参数对肺动脉高压的诊断效能。结果对照组、轻度组、中度组、重度组RVFAC分别为40.80%(37.33%,43.66%)、38.20%(36.80%,38.90%)、36.00%(33.93%,37.55%)、33.60%(31.80%,34.30%)。对照组、轻度组、中度组、重度组TAPSE分别为9.60(8.86,10.82)mm、8.56(8.34,8.76)mm、7.49(6.88,7.92)mm、6.43(6.18,7.05)mm。对照组、轻度组、中度组、重度组TAPSV分别为8.47(7.33,9.20)cm/s、7.78(7.30,8.00)cm/s、6.35(5.84,6.96)cm/s、5.75(5.25,6.42)cm/s。对照组、轻度组、中度组、重度组DD-Tei指数分别为0.44(0.42,0.49)、0.56(0.52,0.58)、0.66(0.63,0.69)、0.76(0.74,0.80)。RVFAC、TAPSE及TAPSV随着肺动脉压力升高而降低(H=67.840,89.510,82.980,均P<0.05),DD-Tei指数随着肺动脉压力升高而增高(H=103.340,P<0.05)。RVFAC、TAPSE、TAPSV与肺动脉压力均呈负相关(r=-0.789,-0.879,-0.841,均P<0.05),DD-Tei指数与肺动脉压力呈正相关(r=0.938,P<0.05)。RVFAC、TAPSE、TAPSV及DD-Tei指数对肺动脉高压均具有较好的诊断效能,曲线下面积分别为0.834,0.923,0.861,0.969,其中DD-Tei指数诊断效能最好。结论DD-Tei指数可以较好地评价肺动脉高压新生儿的右心功能,而且可以反映肺动脉压力变化。展开更多
文摘目的探讨超声心动图检测Tei指数对孕中晚期子痫前期孕妇胎儿心脏功能及出生情况的影响。方法选取2022年1月—2023年10月江西省妇幼保健院收治的重度子痫前期孕妇40例作为A组,轻度子痫前期孕妇50例作为B组,选取2022年1月—2023年10月同期正常孕妇35例作为C组。所有孕妇均予以超声心动图检查,比较3组孕妇新生儿心室Tei指数、心室功能指标及出生情况,采用Pearson相关性分析孕中晚期子痫前期孕妇胎儿心室Tei指数与胎儿出生情况的关系。结果与C组比较(0.25±0.02,0.28±0.02),A组和B组左室Tei指数(0.47±0.03,0.34±0.01)以及右室Tei指数(0.53±0.02,0.37±0.03)均显著上升(P<0.05),与B组比较(0.34±0.01,0.37±0.03),A组左室Tei指数(0.47±0.03)和右室Tei指数(0.53±0.02)均显著上升(P<0.05)。3组左室Tei指数和右室Tei指数比较差异有统计学意义(P<0.05)。与C组比较(64.01±8.94 ms,169.02±7.72 ms,67.44±9.76 ms,172.33±7.30 ms),A组左心室等容时间(71.25±9.80)ms及右心室等容时间(78.25±11.89)ms显著上升,左心室射血时间(162.21±5.36)ms及右心室射血时间(165.24±6.58)ms显著下降;B组右心室等容时间(74.20±10.34)ms显著上升,右心室射血时间(167.83±8.33)ms显著下降(P<0.05)。与B组比较(165.65±6.87)ms,A组左心室射血时间(162.21±5.36)ms显著下降(P<0.05)。3组心室功能指标比较差异有统计学意义(P<0.05)。与C组比较(9.21±0.05分,9.99±0.06分),A组与B组孕妇新生儿出生孕周1min Apgar评分(8.47±1.25分,9.05±0.08分)及5 min Apgar评分(9.83±0.33分,9.95±0.29分)均显著下降(P<0.05),此外,A组孕妇新生儿出生体重(2230.28±536.96)g也显著下降(P<0.05)。与B组比较(3125.37±398.54 g,37.61±1.04周,9.05±0.08分),A组新生儿出生体重(2230.28±536.96)g、出生孕周(34.53±2.14)周、1 min Apgar评分(8.47±1.25)分显著下降(P<0.05)。3组孕妇新生儿出生情况比较差异有统计学意义(P<0.05)。孕中晚期子痫前期孕妇胎儿右心室Tei指数与出生体重、出生孕周、1 min Apgar评分及5 min Apgar评分呈负相关(r=-0.528,-0.385,-0.763,-0.572,均P<0.05)。结论孕中晚期子痫前期胎儿Tei指数与孕妇疾病程度相关,且以右心室出现损伤为主,此外Tei指数与胎儿出生时Apgar评分、孕周及体重相关,有望成为预测胎儿出生情况的一个指标。
基金supported by the National Natural Science Foundation of China(Grant Nos.12204482 and U2330104)the Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi(Grant No.2020L0537)+2 种基金the Natural Science Foundation of Shanxi Province(Grant No.202403021221164)Higher Education Teaching Reform and Innovation Project of Shanxi Province(Grant No.J20220480)Graduate Curriculum Ideological and Political Education Project of Shanxi Normal University(Grant No.010520233013)。
文摘Lead-free halide perovskites provide a promising solution for efficient thermoelectric materials due to their ultralow lattice thermal conductivity(κ_(L)).However,disadvantages such as the electrically resistive nature strongly affect their power factor.In this work,we introduced the Te-based halide perovskites thermoelectric material Cs_(2)TeI_(6),which is already known as a promising candidate for photovoltaic applications due to its moderate band gap.Our findings reveal that Cs_(2)TeI_(6)has an exceptionally ultralow κ_(L)at room temperature,reaching as low as 0.17 W·m^(-1)·K^(-1).We found that the four-phonon scattering processes play a dominant role in suppressing the thermal transport,leading to an approximate 50% reduction in its particle-like thermal conductivity κ_(p) at 300 K.The ultralow κ_(L)can be mainly attributed to the strong discrepancy in bonding strength,which induces large anharmonicity.The flat and dense phonon dispersions result in a strong phonon scattering rate,making it easy to generate wavelike phonon tunneling.After accounting for the wavelike thermal conductivity κ_(c),a nonstandard T^(-0.30)temperature dependence was observed.Benefiting from the ultralow κ_(L),n-type Cs_(2)TeI_(6)is predicted to achieve an extraordinary ZT of 2.26 at 700 K.This work highlights a pathway for searching high-performance and low-cost thermoelectrics based on lead-free halide perovskites.
文摘目的探讨双多普勒Tei指数(DD-Tei指数)评估肺动脉高压新生儿肺动脉压力及右心功能的应用价值。方法选取2020年7月—2021年6月在厦门市儿童医院住院的矫正胎龄28~40周肺动脉高压新生儿90例(肺动脉高压组),按肺动脉压力分为轻度(40~50 mm Hg)、中度(51~70 mm Hg)、重度(>70 mm Hg)3组,其中轻度组35例,中度组30例,重度组25例。另选择同期同孕龄、无肺动脉高压新生儿30例为对照组。测量右心室面积变化分数(RVFAC)、三尖瓣环收缩期峰值位移(TAPSE)、三尖瓣环峰值速度(TAPSV)、DD-Tei指数。绘制受试者工作特征(ROC)曲线,评价右心功能参数对肺动脉高压的诊断效能。结果对照组、轻度组、中度组、重度组RVFAC分别为40.80%(37.33%,43.66%)、38.20%(36.80%,38.90%)、36.00%(33.93%,37.55%)、33.60%(31.80%,34.30%)。对照组、轻度组、中度组、重度组TAPSE分别为9.60(8.86,10.82)mm、8.56(8.34,8.76)mm、7.49(6.88,7.92)mm、6.43(6.18,7.05)mm。对照组、轻度组、中度组、重度组TAPSV分别为8.47(7.33,9.20)cm/s、7.78(7.30,8.00)cm/s、6.35(5.84,6.96)cm/s、5.75(5.25,6.42)cm/s。对照组、轻度组、中度组、重度组DD-Tei指数分别为0.44(0.42,0.49)、0.56(0.52,0.58)、0.66(0.63,0.69)、0.76(0.74,0.80)。RVFAC、TAPSE及TAPSV随着肺动脉压力升高而降低(H=67.840,89.510,82.980,均P<0.05),DD-Tei指数随着肺动脉压力升高而增高(H=103.340,P<0.05)。RVFAC、TAPSE、TAPSV与肺动脉压力均呈负相关(r=-0.789,-0.879,-0.841,均P<0.05),DD-Tei指数与肺动脉压力呈正相关(r=0.938,P<0.05)。RVFAC、TAPSE、TAPSV及DD-Tei指数对肺动脉高压均具有较好的诊断效能,曲线下面积分别为0.834,0.923,0.861,0.969,其中DD-Tei指数诊断效能最好。结论DD-Tei指数可以较好地评价肺动脉高压新生儿的右心功能,而且可以反映肺动脉压力变化。
