Egypt takes a liking to Chinese food For those who think Peking(former name of Beijing)is in China,coming to Egypt would be an eye-opener.There’s a Peking in the upmarket Mohandeseen District of Giza,the city that ha...Egypt takes a liking to Chinese food For those who think Peking(former name of Beijing)is in China,coming to Egypt would be an eye-opener.There’s a Peking in the upmarket Mohandeseen District of Giza,the city that harbors some of the greatest pyramids of Egypt;a second one in the Zamalek District of Greater Cairo frequented by expats,another one in Heliopolis and seven more.展开更多
Fang Chuxiong’s works combine the meticulousness of fine brushwork with the elegance of freehand brushstrokes,making him a distinct figure in the contemporary Chinese art circle.Fang Chuxiong is a representative figu...Fang Chuxiong’s works combine the meticulousness of fine brushwork with the elegance of freehand brushstrokes,making him a distinct figure in the contemporary Chinese art circle.Fang Chuxiong is a representative figure in the field of contemporary Chinese flower-and-bird painting.His artwork masterfully integrates the elements of nature,the charm of living creatures,the subtleties of brushwork,and the vitality of color,exhibiting refined taste and a vibrant style.展开更多
Taste buds relay taste sensory information to the primary taste neurons but depend on those same neurons for essential components to maintain function.While denervation-induced taste bud degeneration and subsequent re...Taste buds relay taste sensory information to the primary taste neurons but depend on those same neurons for essential components to maintain function.While denervation-induced taste bud degeneration and subsequent regeneration were discovered decades ago,the mechanisms underlying these phenomena(e.g.,heterogenous cellular responses to nerve injury and the signaling pathways involved)remain poorly understood.Here,using mouse genetics,nerve injury models,pharmacologic manipulation,and taste bud organoid models,we identify a specific subpopulation of taste cells,predominantly c-Kit-expressing sweet cells,that exhibit superior resistance to nerve injury.We found the c-Kit inhibitor imatinib selectively reduced the number of residual c-Kit-expressing sweet cells at post-operation week 2,subsequently attenuating the re-emergence of other type II cells by post-operation week 4.In taste bud organoids,c-Kit-expressing cells were resistant to R-spondin withdrawal but susceptible to imatinib,while other taste cell types showed the opposite behavior.We also observed a distinct population of residual taste cells that acquired stem-like properties,generating clonal descendent cells among suprabasal keratinocytes independent of c-Kit signaling.Together,our findings reveal that c-Kit signaling confers resilience on c-Kit-expressing sweet cells and supports the broader reconstruction of taste buds during the later regenerative stage following nerve injury.展开更多
A little girl tastes food at the Romanian booth at the 2025 Chengdu Europe Culture Season in Chengdu,southwest China's Sichuan Province,on April 12,2025.
The utilization of Lactobacillus plantarum(LP)in chili sauce production is well-known for its capacity to enhance product quality and sensory attributes.However,there is still limited knowledge regarding the taste-act...The utilization of Lactobacillus plantarum(LP)in chili sauce production is well-known for its capacity to enhance product quality and sensory attributes.However,there is still limited knowledge regarding the taste-active metabolites in the sauce.To bridge this gap,our study employed metabolomics and webbased computational tools to investigate the dynamic changes of taste-active metabolites during chili sauce fermentation.By leveraging the advantages of the feature-based molecular network(FBMN),we conducted a rapid annotation of metabolites,successfully identifying 205 metabolites,a considerable portion of which were previously unreported.Through the utilization of the Virtual Taste tool,we identified dihydrosphingosine,lactic acid,isoleucine,phytosphingosine,and gluconic acid as potential taste indicators for quality control.Pathway enrichment analysis further supported their primary involvement in key biochemical pathways,including amino acid t RNA biosynthesis,phenylalanine,tyrosine,tryptophan biosynthesis,and sphingolipid metabolism.This investigation provides valuable insights into the underlying mechanisms contributing to the distinctive flavor profile of chili sauce.展开更多
1 Himalayan salt,a pink organic variety of the essential food sourced from Pakistan,is becoming increasingly popular in China,fueled by growing demand from quality‑conscious consumers.Himalayan salt is on the dining t...1 Himalayan salt,a pink organic variety of the essential food sourced from Pakistan,is becoming increasingly popular in China,fueled by growing demand from quality‑conscious consumers.Himalayan salt is on the dining tables of more Chinese consumers on occasions such as camping,barbecue parties and grilling steak at home,and it has been used to improve taste and for decorative purposes.展开更多
Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production.In addition,sugars can act as signaling molecules.To study sugar signaling at the systemic level,there is an u...Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production.In addition,sugars can act as signaling molecules.To study sugar signaling at the systemic level,there is an urgent need to systematically identify sugar-sensing proteins and nucleic acids.I propose the terms“swodkoreceptor”and“swodkocrine signaling,”derived from the Polish word“slodki”meaning“sweet,”to comprise all sugar-sensing proteins and signaling events,respectively,regardless of their cellular location and signaling domains.This proposal is intended to facilitate the inclusion of proteins such as the Escherichia coli Lac I repressor as an allolactose receptor,human glucokinase regulatory protein(GCKR)as a fructose receptor,and other sugar-binding based allosterically regulated enzymes and transcription factors as sugar-sensing receptors.In addition,enzyme-interacting proteins whose interaction state is regulated by sugar binding have also been proposed as sugar receptors.The systemic study of protein-and nucleic-acid-based swodkoreceptors may help to identify organelle-specific swodkoreceptors and to also address receptor duality.The study of intra-and inter-organism swodkocrine signaling and its crosstalk with gasocrine signaling may help to understand the etiology of diseases due to dysregulation in sugar homeostasis and signaling.展开更多
[Objective] The paper was to study adsorption dynamics of calyx aroma onto basic tea in scenting process of calyx-scented tea, so as to increase aroma and quality of products. [Method] Adsorption experiment was carrie...[Objective] The paper was to study adsorption dynamics of calyx aroma onto basic tea in scenting process of calyx-scented tea, so as to increase aroma and quality of products. [Method] Adsorption experiment was carried out in a hermetic container, and the effect of calyx amount, contact time, moisture content of basic tea and temperature on the scenting process was studied. [Result] The optimal moisture and temperature for scenting process was 4% and 10 ℃, respectively. [Conclusion] The scenting process accorded pseudo-first-order kinetic model, and the adsorption dynamic data of total process could better fit pseudo-second-order kinetic model.展开更多
Huizhou-style gardens have been greatly influenced by Huizhou culture, their plant landscapes have also been integrated with various aspects of Huizhou culture, which demonstrated the ideology, historical and cultural...Huizhou-style gardens have been greatly influenced by Huizhou culture, their plant landscapes have also been integrated with various aspects of Huizhou culture, which demonstrated the ideology, historical and cultural connotation of the society in an abstract and impalpable way. In this study, Huizhou-style miniature landscapes, plants of virtual implications, flowers or fruit trees of special connotations are taken for examples to analyze the influence of Xin’an Neo-Confucianism on plant landscapes in Huizhou-style gardens, the demonstration of Huizhou businessmen’s aesthetic tastes, as well as folk cultures of Huizhou, which implies that plant landscapes in Huizhou-style gardens are those incorporating with humanistic spirits, ornamental and practical uses. This study aims to provide references for further researches in the present situation of ancient Huizhou areas, protection of ancient Huizhou-style gardens and construction of new-style Huizhou gardens.展开更多
上期的第一个话题“旅游”是我们每个人在生活中都会经历或已经经历过的事情。要说人们为什么旅游,原因实在很多,关键是怎样条理清楚地表达出来。考生应首先说出最主要的目的,可以用一两句话概括,然后再谈具体内容。如:Travelling can b...上期的第一个话题“旅游”是我们每个人在生活中都会经历或已经经历过的事情。要说人们为什么旅游,原因实在很多,关键是怎样条理清楚地表达出来。考生应首先说出最主要的目的,可以用一两句话概括,然后再谈具体内容。如:Travelling can broaden our mind.With thedevelopment of high technology,the world isbecoming a global village.It is very important tolearn the culture of other places or even other countries.Sometimes we can learn more through travelling thanwe do from textbooks.When we go to a new place,展开更多
文摘Egypt takes a liking to Chinese food For those who think Peking(former name of Beijing)is in China,coming to Egypt would be an eye-opener.There’s a Peking in the upmarket Mohandeseen District of Giza,the city that harbors some of the greatest pyramids of Egypt;a second one in the Zamalek District of Greater Cairo frequented by expats,another one in Heliopolis and seven more.
文摘Fang Chuxiong’s works combine the meticulousness of fine brushwork with the elegance of freehand brushstrokes,making him a distinct figure in the contemporary Chinese art circle.Fang Chuxiong is a representative figure in the field of contemporary Chinese flower-and-bird painting.His artwork masterfully integrates the elements of nature,the charm of living creatures,the subtleties of brushwork,and the vitality of color,exhibiting refined taste and a vibrant style.
基金supported by a National Research Foundation of Korea(NRF)grant funded by the Korean Government(Ministry of Science and ICT,RS-2023-00208193 to Y.T.J.)by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI)funded by the Ministry of Health&Welfare(RS-2024-00403511 to D.-H.K.)by a Korea University grant(K2117151 to Y.T.J.)。
文摘Taste buds relay taste sensory information to the primary taste neurons but depend on those same neurons for essential components to maintain function.While denervation-induced taste bud degeneration and subsequent regeneration were discovered decades ago,the mechanisms underlying these phenomena(e.g.,heterogenous cellular responses to nerve injury and the signaling pathways involved)remain poorly understood.Here,using mouse genetics,nerve injury models,pharmacologic manipulation,and taste bud organoid models,we identify a specific subpopulation of taste cells,predominantly c-Kit-expressing sweet cells,that exhibit superior resistance to nerve injury.We found the c-Kit inhibitor imatinib selectively reduced the number of residual c-Kit-expressing sweet cells at post-operation week 2,subsequently attenuating the re-emergence of other type II cells by post-operation week 4.In taste bud organoids,c-Kit-expressing cells were resistant to R-spondin withdrawal but susceptible to imatinib,while other taste cell types showed the opposite behavior.We also observed a distinct population of residual taste cells that acquired stem-like properties,generating clonal descendent cells among suprabasal keratinocytes independent of c-Kit signaling.Together,our findings reveal that c-Kit signaling confers resilience on c-Kit-expressing sweet cells and supports the broader reconstruction of taste buds during the later regenerative stage following nerve injury.
文摘A little girl tastes food at the Romanian booth at the 2025 Chengdu Europe Culture Season in Chengdu,southwest China's Sichuan Province,on April 12,2025.
基金the financial support from Sichuan Technology Development Program,China(2020YFN0056,2021ZHCG0051,2020YFN0094,2021YFN0048,2020YFN0151)the Natural Science Foundation of Sichuan Province(2022NSFSC0105)Pidu 100 Innovative Talents Program(2022)。
文摘The utilization of Lactobacillus plantarum(LP)in chili sauce production is well-known for its capacity to enhance product quality and sensory attributes.However,there is still limited knowledge regarding the taste-active metabolites in the sauce.To bridge this gap,our study employed metabolomics and webbased computational tools to investigate the dynamic changes of taste-active metabolites during chili sauce fermentation.By leveraging the advantages of the feature-based molecular network(FBMN),we conducted a rapid annotation of metabolites,successfully identifying 205 metabolites,a considerable portion of which were previously unreported.Through the utilization of the Virtual Taste tool,we identified dihydrosphingosine,lactic acid,isoleucine,phytosphingosine,and gluconic acid as potential taste indicators for quality control.Pathway enrichment analysis further supported their primary involvement in key biochemical pathways,including amino acid t RNA biosynthesis,phenylalanine,tyrosine,tryptophan biosynthesis,and sphingolipid metabolism.This investigation provides valuable insights into the underlying mechanisms contributing to the distinctive flavor profile of chili sauce.
文摘1 Himalayan salt,a pink organic variety of the essential food sourced from Pakistan,is becoming increasingly popular in China,fueled by growing demand from quality‑conscious consumers.Himalayan salt is on the dining tables of more Chinese consumers on occasions such as camping,barbecue parties and grilling steak at home,and it has been used to improve taste and for decorative purposes.
基金supported by the National Science Centre grants,Grant/Award Number:SONATA-BIS 2020/38/E/NZ3/00090 and SONATA 2021/43/D/NZ3/01798。
文摘Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production.In addition,sugars can act as signaling molecules.To study sugar signaling at the systemic level,there is an urgent need to systematically identify sugar-sensing proteins and nucleic acids.I propose the terms“swodkoreceptor”and“swodkocrine signaling,”derived from the Polish word“slodki”meaning“sweet,”to comprise all sugar-sensing proteins and signaling events,respectively,regardless of their cellular location and signaling domains.This proposal is intended to facilitate the inclusion of proteins such as the Escherichia coli Lac I repressor as an allolactose receptor,human glucokinase regulatory protein(GCKR)as a fructose receptor,and other sugar-binding based allosterically regulated enzymes and transcription factors as sugar-sensing receptors.In addition,enzyme-interacting proteins whose interaction state is regulated by sugar binding have also been proposed as sugar receptors.The systemic study of protein-and nucleic-acid-based swodkoreceptors may help to identify organelle-specific swodkoreceptors and to also address receptor duality.The study of intra-and inter-organism swodkocrine signaling and its crosstalk with gasocrine signaling may help to understand the etiology of diseases due to dysregulation in sugar homeostasis and signaling.
基金Supported by Special Major Build of China and Nature Science Research Foundations of Sichuan Agricultural University(06370101)~~
文摘[Objective] The paper was to study adsorption dynamics of calyx aroma onto basic tea in scenting process of calyx-scented tea, so as to increase aroma and quality of products. [Method] Adsorption experiment was carried out in a hermetic container, and the effect of calyx amount, contact time, moisture content of basic tea and temperature on the scenting process was studied. [Result] The optimal moisture and temperature for scenting process was 4% and 10 ℃, respectively. [Conclusion] The scenting process accorded pseudo-first-order kinetic model, and the adsorption dynamic data of total process could better fit pseudo-second-order kinetic model.
文摘Huizhou-style gardens have been greatly influenced by Huizhou culture, their plant landscapes have also been integrated with various aspects of Huizhou culture, which demonstrated the ideology, historical and cultural connotation of the society in an abstract and impalpable way. In this study, Huizhou-style miniature landscapes, plants of virtual implications, flowers or fruit trees of special connotations are taken for examples to analyze the influence of Xin’an Neo-Confucianism on plant landscapes in Huizhou-style gardens, the demonstration of Huizhou businessmen’s aesthetic tastes, as well as folk cultures of Huizhou, which implies that plant landscapes in Huizhou-style gardens are those incorporating with humanistic spirits, ornamental and practical uses. This study aims to provide references for further researches in the present situation of ancient Huizhou areas, protection of ancient Huizhou-style gardens and construction of new-style Huizhou gardens.
文摘上期的第一个话题“旅游”是我们每个人在生活中都会经历或已经经历过的事情。要说人们为什么旅游,原因实在很多,关键是怎样条理清楚地表达出来。考生应首先说出最主要的目的,可以用一两句话概括,然后再谈具体内容。如:Travelling can broaden our mind.With thedevelopment of high technology,the world isbecoming a global village.It is very important tolearn the culture of other places or even other countries.Sometimes we can learn more through travelling thanwe do from textbooks.When we go to a new place,
