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Infrared small target detection based on density peaks searching and weighted multi-feature local difference
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作者 JI Bin FAN Pengxiang +2 位作者 WANG Mengli LIU Yang XU Jiafeng 《Optoelectronics Letters》 2025年第4期218-225,共8页
To address the issues of unknown target size,blurred edges,background interference and low contrast in infrared small target detection,this paper proposes a method based on density peaks searching and weighted multi-f... To address the issues of unknown target size,blurred edges,background interference and low contrast in infrared small target detection,this paper proposes a method based on density peaks searching and weighted multi-feature local difference.Firstly,an improved high-boost filter is used for preprocessing to eliminate background clutter and high-brightness interference,thereby increasing the probability of capturing real targets in the density peak search.Secondly,a triple-layer window is used to extract features from the area surrounding candidate targets,addressing the uncertainty of small target sizes.By calculating multi-feature local differences between the triple-layer windows,the problems of blurred target edges and low contrast are resolved.To balance the contribution of different features,intra-class distance is used to calculate weights,achieving weighted fusion of multi-feature local differences to obtain the weighted multi-feature local differences of candidate targets.The real targets are then extracted using the interquartile range.Experiments on datasets such as SIRST and IRSTD-IK show that the proposed method is suitable for various complex types and demonstrates good robustness and detection performance. 展开更多
关键词 extract featur background clutter density peaks searching infrared small target detection weighted multi feature local difference capturing real targets density peak infrared small target detectionthis
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Data matching and association based on the arc-segment difference method
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作者 Jiannan Sun Zhe Kang +1 位作者 Zhenwei Li Cunbo Fan 《Astronomical Techniques and Instruments》 2025年第5期299-309,共11页
In response to the issue of fuzzy matching and association when optical observation data are matched with the orbital elements in a catalog database,this paper proposes a matching and association strategy based on the... In response to the issue of fuzzy matching and association when optical observation data are matched with the orbital elements in a catalog database,this paper proposes a matching and association strategy based on the arcsegment difference method.First,a matching error threshold is set to match the observation data with the known catalog database.Second,the matching results for the same day are sorted on the basis of target identity and observation residuals.Different matching error thresholds and arc-segment dynamic association thresholds are then applied to categorize the observation residuals of the same target across different arc-segments,yielding matching results under various thresholds.Finally,the orbital residual is computed through orbit determination(OD),and the positional error is derived by comparing the OD results with the orbit track from the catalog database.The appropriate matching error threshold is then selected on the basis of these results,leading to the final matching and association of the fuzzy correlation data.Experimental results showed that the correct matching rate for data arc-segments is 92.34% when the matching error threshold is set to 720″,with the arc-segment difference method processing the results of an average matching rate of 97.62% within 8 days.The remaining 5.28% of the fuzzy correlation data are correctly matched and associated,enabling identification of orbital maneuver targets through further processing and analysis.This method substantially enhances the efficiency and accuracy of space target cataloging,offering robust technical support for dynamic maintenance of the space target database. 展开更多
关键词 Optical data processing Space target identification Fuzzy correlation Arc-segment difference method Orbit determination
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A Moving IR Point Target Detection Algorithm Based on Reverse Phase Feature of Neighborhood in Difference Between Neighbor Frame Images 被引量:3
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作者 朱风云 秦世引 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2006年第3期225-232,共8页
An algorithm for detecting moving IR point target in complex background is proposed, which is based on the Reverse Phase Feature of Neighborhood (RPFN) of target in difference between neighbor frame images that two ... An algorithm for detecting moving IR point target in complex background is proposed, which is based on the Reverse Phase Feature of Neighborhood (RPFN) of target in difference between neighbor frame images that two positions of the target in the difference image are near and the gray values of them are close to in absolute value but with inverse sign. Firstly, pairs of points with RPFN are detected in the difference image between neighbor frame images, with which a virtual vector graph is made, and then the moving point target can be detected by the vectors' sequence cumulated in vector graphs. In addition, a theorem for the convergence of detection of target contrail by this algorithm is given and proved so as to afford a solid guarantee for practical applications of the algorithm proposed in this paper. Finally, some simulation results with 1000 frames from 10 typical images in complex background show that moving point targets with SNR not lower than 1.5 can be detected effectively. 展开更多
关键词 pattern recognition target detection point target difference image RPFN
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ANALYSIS OF TARGET TRACKING BASED ON RANGE DIFFERENCE MEASUREMENT OF MULTISTATIC RADAR SYSTEM 被引量:1
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作者 Wei Chongyu Xu Shanjia Wang Dongjin (Dept. of Electronic Engineering & Information Science of USTC, Hefei 230027, China) 《Journal of Electronics(China)》 2000年第4期297-303,共7页
An analysis is presented for target tracking with short range multistatic radar system in this paper. The velocity vector is introduced into the model to depict target motion more precisely. The system measurement equ... An analysis is presented for target tracking with short range multistatic radar system in this paper. The velocity vector is introduced into the model to depict target motion more precisely. The system measurement equation is such constructed on the basis of range difference that make the tracking model independent of the transmitter position. Therefore the algorithm is very much suitable for the case that the transmitter is not fixed. Simulation results show that the algorithm has the advantages of fast tracking and small steady tracking errors, and can be used for tracking target in short range with multistatic radar system. 展开更多
关键词 Multistatic RADAR system target TRACKING RANGE difference
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A NEW METHOD FOR DETERMINING THE LOCATION AND LENGTH OF A THIN CYLINDRICAL TARGET WITH RANGE DIFFERENCE OF A MULTISTATIC RADAR SYSTEM 被引量:1
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作者 Wei Chongyu Xu Shanjia Wang Dongjin (Dept. of Electron. Eng. and Info. Sci., Univ. of Sci. and Technol. of China, Hefei 230027) 《Journal of Electronics(China)》 2000年第2期139-145,共7页
This paper describes a short range target location system based on the range difference information of a T-R4 multistatic radar system with FMCW signal. A new method is proposed to determine the location and length of... This paper describes a short range target location system based on the range difference information of a T-R4 multistatic radar system with FMCW signal. A new method is proposed to determine the location and length of a thin cylindrical target making use of the high resolution of wide band FMCW signal and the spectrum characteristics of the target echo. Formulae are derived for target location and its length estimation being independent of the transmitter position. System performances are simulated with the proposed algorithm and the results are given for various situations. 展开更多
关键词 Multistatic radar target LOCATION Range difference FMCW
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Fast-moving target tracking based on mean shift and frame-difference methods 被引量:32
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作者 Hongpeng Yin Yi Chai +1 位作者 Simon X. Yang Xiaoyan Yang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2011年第4期587-592,共6页
The mean shift tracker has difficulty in tracking fast moving targets and suffers from tracking error accumulation problem. To overcome the limitations of the mean shift method, a new approach is proposed by integrati... The mean shift tracker has difficulty in tracking fast moving targets and suffers from tracking error accumulation problem. To overcome the limitations of the mean shift method, a new approach is proposed by integrating the mean shift algorithm and frame-difference methods. The rough position of the moving tar- get is first located by the direct frame-difference algorithm and three-frame-difference algorithm for the immobile camera scenes and mobile camera scenes, respectively. Then, the mean shift algorithm is used to achieve precise tracking of the target. Several tracking experiments show that the proposed method can effectively track first moving targets and overcome the tracking error accumulation problem. 展开更多
关键词 mean shift frame-difference method target tracking computer vision.
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Fusion Reaction Rate Coefficient for Different Beam and Target Scenarios
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作者 欧巍 曾宪俊 +1 位作者 邓柏权 苟富均 《Chinese Physics Letters》 SCIE CAS CSCD 2015年第2期43-47,共5页
Fusion power output is proportional not only to the fuel particle number densities participating in reaction but also to the fusion reaction rate coefficient (or reactivity), which is dependent on reactant velocity ... Fusion power output is proportional not only to the fuel particle number densities participating in reaction but also to the fusion reaction rate coefficient (or reactivity), which is dependent on reactant velocity distribution functions. They are usuMly assumed to be dual Maxwellian distribution functions with the same temperature for thermal nuclear fusion circumstances. However, if high power neutral beam injection and minority ion species ICRF plasma heating, or multi-pinched plasma beam head-on collision, in a converging region are required and investigated in future large scale fusion reactors, then the fractions of the injected energetic fast ion tail resulting from ionization or charge exchange will be large enough and their contribution to the non-Maxwellian distribution functions is not negligible, hence to the fusion reaction rate coefficient or calculation of fusion power. In such cases, beam-target, and beam-beam reaction enhancement effect contributions should play very important roles. In this paper, several useful formulae to calculate the fusion reaction rate coefticient for different beam and target combination scenarios are derived in detail 展开更多
关键词 Fusion Reaction Rate Coefficient for different Beam and target Scenarios exp
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Target acquisition performance in the presence of JPEG image compression
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作者 Boban Bondzulic Nenad Stojanovic +3 位作者 Vladimir Lukin Sergey A.Stankevich Dimitrije Bujakovic Sergii Kryvenko 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期30-41,共12页
This paper presents an investigation on the effect of JPEG compression on the similarity between the target image and the background,where the similarity is further used to determine the degree of clutter in the image... This paper presents an investigation on the effect of JPEG compression on the similarity between the target image and the background,where the similarity is further used to determine the degree of clutter in the image.Four new clutter metrics based on image quality assessment are introduced,among which the Haar wavelet-based perceptual similarity index,known as HaarPSI,provides the best target acquisition prediction results.It is shown that the similarity between the target and the background at the boundary between visually lossless and visually lossy compression does not change significantly compared to the case when an uncompressed image is used.In future work,through subjective tests,it is necessary to check whether this presence of compression at the threshold of just noticeable differences will affect the human target acquisition performance.Similarity values are compared with the results of subjective tests of the well-known target Search_2 database,where the degree of agreement between objective and subjective scores,measured through linear correlation,reached a value of 90%. 展开更多
关键词 JPEG compression target acquisition performance Image quality assessment Just noticeable difference Probability of target detection target mean searching time
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Cultural differences between English and Chinese color words
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作者 龙占红 《中国校外教育》 2008年第6期84-,142,共2页
color words may show different cultural connotation of each language in some degree.While translating,we should handle color words appropriately according to cultural differences in both the original and target langua... color words may show different cultural connotation of each language in some degree.While translating,we should handle color words appropriately according to cultural differences in both the original and target language.This paper brings a discussion of cultural differences between English and Chinese color words. 展开更多
关键词 CULTURAL differenceS CULTURAL CONNOTATION ENGLISH and Chinese target LANGUAGE
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A Method to Obtain the Moving Speed of Uncooperative Target Based on Only Two Measurements
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作者 Tao Yu 《Advances in Aerospace Science and Technology》 2024年第1期1-9,共9页
The existing research results show that a fixed single station must conduct three consecutive frequency shift measurements and obtain the target’s moving speed by constructing two frequency difference equations. This... The existing research results show that a fixed single station must conduct three consecutive frequency shift measurements and obtain the target’s moving speed by constructing two frequency difference equations. This article proposes a new method that requires only two consecutive measurements. While using the azimuth measurement to obtain the angular difference between two radial distances, it also conducts two consecutive Doppler frequency shift measurements at the same target azimuth. On the basis of this measurement, a frequency difference equation is first constructed and solved jointly with the Doppler frequency shift equation. By eliminating the velocity variable and using the measured angular difference to obtain the target’s lead angle, the target’s velocity can be solved by using the Doppler frequency shift equation again. The new method avoids the condition that the target must move equidistantly, which not only provides an achievable method for engineering applications but also lays a good foundation for further exploring the use of steady-state signals to achieve passive positioning. 展开更多
关键词 Moving Speed Non-Cooperative target Doppler Frequency Shift Frequency difference Equation AZIMUTH Steady-State Signal Passive Location
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基于UHPLC-QE-MS非靶向代谢组学的当归不同药用部位差异代谢物分析
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作者 杨秀娟 魏江霞 +4 位作者 杨志军 田一虹 段国建 陈晖 李硕 《药学学报》 北大核心 2025年第4期1093-1102,共10页
本研究利用UHPLC-QE-MS结合非靶向代谢组学技术鉴定当归不同药用部位(归头、归身、归尾)的差异性化合物,通过主成分分析和正交偏最小二乘-判别分析方法筛选差异代谢物,并分析相关代谢通路。结果在当归不同药用部位中共鉴定出18类1072个... 本研究利用UHPLC-QE-MS结合非靶向代谢组学技术鉴定当归不同药用部位(归头、归身、归尾)的差异性化合物,通过主成分分析和正交偏最小二乘-判别分析方法筛选差异代谢物,并分析相关代谢通路。结果在当归不同药用部位中共鉴定出18类1072个代谢物,主要为萜类、苯丙素类、脂质及其衍生物、生物碱、黄酮类、有机酸及其衍生物等,其中,归头对比归身映射530个差异代谢物、归头对比归尾映射565个差异代谢物、归身对比归尾映射474个差异代谢物,而山柰酚、绿原酸、阿魏酸、藁本内酯、甘草素、芦丁等成分主要富集于归尾,柚皮素、芹菜素等成分主要富集于归身,雌二醇、川芎嗪等成分主要富集于归头;差异代谢物主要富集在类黄酮、黄酮以及黄酮醇的生物合成、吲哚生物碱生物合成、色氨酸代谢、苯丙氨酸代谢等通路上。该研究通过非靶向代谢组学技术对当归不同药用部位的差异代谢物进行比较分析,为临床合理、精准应用当归不同药用部位提供科学支撑。 展开更多
关键词 当归 不同药用部位 代谢组学 差异代谢物 UHPLC-QE-MS
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非靶向代谢组学分析锦灯笼不同部位的代谢物差异
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作者 金银萍 李政 +1 位作者 邓莉 张浩 《食品工业科技》 北大核心 2025年第19期287-296,共10页
采用非靶向代谢组学方法,分析锦灯笼宿萼、果、茎和根等不同部位间代谢物的差异性。运用超高效液相色谱-四极杆-静电场轨道肼高分辨质谱(UHPLC-Q-Orbitrap HRMS),通过主成分分析(PCA)、正交偏最小二乘判别分析(OPLS-DA)、聚类分析(HCA)... 采用非靶向代谢组学方法,分析锦灯笼宿萼、果、茎和根等不同部位间代谢物的差异性。运用超高效液相色谱-四极杆-静电场轨道肼高分辨质谱(UHPLC-Q-Orbitrap HRMS),通过主成分分析(PCA)、正交偏最小二乘判别分析(OPLS-DA)、聚类分析(HCA)、代谢物及其代谢通路差异性分析,对锦灯笼不同部位的代谢组学特征进行研究。结果显示,从锦灯笼不同部位中共检测到1416种代谢物,其含量组成以有机酸、生物碱、氨基酸及其衍生物等为主;锦灯笼不同部位的代谢物存在显著差异,宿萼中代谢物种类含量较高的是黄酮、苯丙素、维生素类,果中代谢物种类含量较高的是有机酸、生物碱、甾体类,茎中代谢物种类含量较高的是萜、黄酮、酯、酚酸类,根中代谢物种类含量较高的是糖、脂、氨基酸及其衍生物类;OPLS-DA分析筛选出113个差异代谢物(变量权重值VIP>1.7和P<0.05),其中有机酸、生物碱、脂类等成分占比较高,主要参与不饱和脂肪酸生物合成、柠檬酸循环、丙酮酸等代谢途径;在鉴定出的黄酮类成分中有20%均为差异代谢物,并且此类成分在差异代谢物中变异比例最大。该研究可为锦灯笼不同部位的成分差异以及资源的综合开发利用提供理论参考。 展开更多
关键词 锦灯笼 不同部位 非靶向代谢组学 差异代谢物
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基于广泛靶向代谢组学分析不同品种黑老虎果籽脂质差异
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作者 李逢振 杨琪 梁忠厚 《天然产物研究与开发》 北大核心 2025年第8期1478-1485,1459,共9页
为探究不同品种的黑老虎果籽的脂质含量及差异,本研究采用广泛靶向代谢组学技术鉴定并分析了虎绿、大红和粉红黑老虎果籽间脂质组分差异和高度富集成分。结果表明,总脂质含量表现为1组(虎绿果籽)>2组(大红果籽)>3组(粉红果籽),脂... 为探究不同品种的黑老虎果籽的脂质含量及差异,本研究采用广泛靶向代谢组学技术鉴定并分析了虎绿、大红和粉红黑老虎果籽间脂质组分差异和高度富集成分。结果表明,总脂质含量表现为1组(虎绿果籽)>2组(大红果籽)>3组(粉红果籽),脂质成分包括1个游离脂肪酸(free fatty acids,FFA)、3种甘油脂、13种甘油磷脂、4种鞘脂及2种固醇脂等,其中甘油三酯含量最高;比较3组果籽间脂质差异高达172个,其中二酰基甘油-3-O-羧基羟甲基胆碱、二酰基甘油三甲基高丝氨酸及溶血磷脂酰肌醇脂质含量差异尤为显著;比较3组与1、2组间的差异脂质种类,甘油磷脂的数量最多;1组与2组间比较,差异脂质种类中游离脂肪酸的数量最多;进一步通过富集分析发现,黑老虎果籽组间的差异脂质主要富集在以下几条代谢通路中:甘油磷脂代谢、花生四烯酸代谢、亚油酸代谢、脂肪酸生物合成、不饱和脂肪酸生物合成及鞘脂代谢等。不同品种黑老虎果籽的脂质类组分,含量及代谢通路方面具有显著差异,揭示不同品种黑老虎果籽的环境逆境适应能力及潜在功能特性。 展开更多
关键词 黑老虎果籽 脂质差异 代谢通路 广泛靶向 代谢组学分析
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图像目标抗遮挡视觉差补偿算法仿真
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作者 赵海燕 杜丽娟 +1 位作者 刘琨 肖琳 《计算机仿真》 2025年第1期244-248,共5页
由于场景复杂、光线变化等因素的影响,图像中的目标物体可能被遮挡,导致视差的失真和误差,从而影响对图像目标的精准跟踪。为了有效解决上述问题,提出图像目标抗遮挡视觉差补偿算法。将图像转移到HSI颜色空间中,检测并消除图像中存在的... 由于场景复杂、光线变化等因素的影响,图像中的目标物体可能被遮挡,导致视差的失真和误差,从而影响对图像目标的精准跟踪。为了有效解决上述问题,提出图像目标抗遮挡视觉差补偿算法。将图像转移到HSI颜色空间中,检测并消除图像中存在的噪声;将去噪后的图像输入YOLOv3网络中,检测并定位目标区域;根据人眼视觉特性建立二维视觉差异直方图,结合LDR算法对目标区域展开增强处理,通过灰度补偿方法对目标区域展开灰度补偿,避免过度增强现象的发生,实现目标抗遮挡视觉差补偿。实验结果表明,所提算法的图像去噪效果好、目标定位精度高、补偿效果好、补偿效率高。 展开更多
关键词 颜色空间 目标定位 二维视觉差异直方图 视觉差补偿
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多注意力对比学习的红外小目标检测
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作者 边小勇 胡其仁 《计算机应用》 北大核心 2025年第11期3707-3712,共6页
红外小目标检测(IRSTD)是目标检测领域中的研究热点和难点,具有像素小、对比度低和无纹理的特性,难以从小目标有限和扭曲的信息中学习正确的特征表示,因此IRSTD方法依然面临挑战。针对以上问题,提出多注意力对比学习的IRSTD方法。首先,... 红外小目标检测(IRSTD)是目标检测领域中的研究热点和难点,具有像素小、对比度低和无纹理的特性,难以从小目标有限和扭曲的信息中学习正确的特征表示,因此IRSTD方法依然面临挑战。针对以上问题,提出多注意力对比学习的IRSTD方法。首先,采用U-Net为基本框架,在编码阶段提出一种融合频率注意力(FA)和空间注意力的上下文混合块(CMB),产生初级注意力特征图;其次,在解码阶段设计多核中心差分卷积(MKCDC),用于提取小目标在不同尺度下都稳定表征的核心信息;最后,联合二元交叉熵损失和对比损失函数训练小目标检测网络,提高小目标特征表示能力,得到富于判别的小目标检测模型。实验结果表明,在IRSTD-1k和NUAA-SIRST数据集上,所提方法的检测率(Pd)分别达到96.63%和100.00%,与密集嵌套的注意力网络(DNA-Net)相比,分别提高了4.71和1.90个百分点。可见,所提方法有效提高了IRSTD性能。 展开更多
关键词 深度学习 小目标检测 注意力U-Net 中心差分卷积 对比学习
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基于局部对比和特征增强的红外小目标检测网络
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作者 朵琳 张芸 +2 位作者 殷瑜 段威 任勇 《陕西理工大学学报(自然科学版)》 2025年第3期79-87,共9页
针对杂波背景下红外小目标检测面临的目标分布稀疏、对比度低以及在深层网络中极易丢失等问题,以U-Net架构为基准,提出了一种基于局部对比和特征增强的检测网络。首先,用局部对比特征提取模块结合普通卷积和空洞卷积,大范围内探索图像... 针对杂波背景下红外小目标检测面临的目标分布稀疏、对比度低以及在深层网络中极易丢失等问题,以U-Net架构为基准,提出了一种基于局部对比和特征增强的检测网络。首先,用局部对比特征提取模块结合普通卷积和空洞卷积,大范围内探索图像之间的语义信息,对目标特征进行粗略提取。再利用中心差分卷积,通过局部对比小目标与背景之间的差异,实现目标与背景的分离。然后,利用注意力机制设计了特征增强模块,该模块在通道方向上通过自适应地校准特征响应,进一步加深红外小目标与周边区域的对比度,增强特征表示,防止目标特征在深层网络中丢失。在4个公开数据集上的实验表明,该方法与现有其他方法相比具有明显的优越性和更强的泛化能力。 展开更多
关键词 红外小目标检测 中心差分卷积 注意力机制 深度学习
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中国双碳目标达成的区域差异预测及其影响因素 被引量:2
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作者 谌莹 石柳 《生态学报》 北大核心 2025年第10期4789-4802,共14页
为明晰我国区域间双碳目标达成的进度和峰值的差异性特征,进而展开区域双碳目标压力测试,选用中国30个省域21年的数据,先从省域人均碳排放和人均RGDP两个指标维度对各省域的低碳经济发展现状展开聚类分析,接着利用半参回归方法验证人均... 为明晰我国区域间双碳目标达成的进度和峰值的差异性特征,进而展开区域双碳目标压力测试,选用中国30个省域21年的数据,先从省域人均碳排放和人均RGDP两个指标维度对各省域的低碳经济发展现状展开聚类分析,接着利用半参回归方法验证人均碳排放峰值存在性,并运用FGLS实证方法检验基于EKC模型、IPAT模型以及ImPACT模型构建的实证模型稳健性,进而分别对常住人口、RGDP、碳强度和能源结构四个关键影响因素设置高低情景,运用上述实证模型对全样本、分组样本和省域样本进行峰值预测和比较分析。结果显示:①各分组样本的半参回归结果接近于“倒U型”,预示了人均碳排放峰值的客观存在性,为使用实证模型展开峰值分析提供了支持。②各组样本在不同实证模型下计算出来的峰值比较接近,但单个模型下各组峰值差异明显,说明不同类型省域出现峰值所对应的人均RGDP水平差别较大。③通过比较各组系数和峰值数据可知人口和经济增长对峰值的影响最为关键。④预测结果显示,30个省域呈现出两类分化特征,能源消费结构是导致区域达峰时间和峰值大小产生差异的关键因素。 展开更多
关键词 双碳目标 碳排放峰值 区域差异 影响因素
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基于生物信息学及动物实验探究人参-黄精配伍干预创伤后应激障碍的作用及机制
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作者 丁可可 陈道康 +4 位作者 王婧吉 王训翠 张峥嵘 杨绍杰 朱国旗 《中国药理学通报》 北大核心 2025年第6期1099-1107,共9页
目的评价人参-黄精不同配比对SPS诱导的小鼠PTSD样行为的改善作用,并利用生物信息学及动物实验探究其作用机制。方法人参-黄精以1∶0(RH1)、2∶1(RH2)、1∶2(RH3)、0∶1(RH4)四种配比(总共60 g)进行提取,UPLC-UV法检测不同配比人参-黄... 目的评价人参-黄精不同配比对SPS诱导的小鼠PTSD样行为的改善作用,并利用生物信息学及动物实验探究其作用机制。方法人参-黄精以1∶0(RH1)、2∶1(RH2)、1∶2(RH3)、0∶1(RH4)四种配比(总共60 g)进行提取,UPLC-UV法检测不同配比人参-黄精的中药有效成分人参皂苷Rg1、Rb1及多糖提取率;建立SPS小鼠模型,分别灌胃给药RH1、RH2、RH3及RH4(400 mg·kg^(-1))14 d后,行为学评价PTSD样行为;ELISA测定血清CORT、IL-1β及IL-10含量;生物信息学分析筛选潜在靶点;Western blot检测海马Calpain-1、PSD95和BDNF蛋白表达。结果SPS小鼠经人参-黄精不同配比提取物治疗后,能改善SPS小鼠PTSD样行为,RH2效果最佳,降低CORT及IL-1β水平,提高IL-10含量。筛选PTSD疾病潜在作用靶点160个,分别富集在抑制突触损伤、发挥抗氧化特性及抑制神经炎症等功能。RH2能阻止SPS诱导的Calpain-1、PSD95、BDNF的表达下降和GluN2B的升高。分子对接显示,人参皂苷Rg1和Rb1与Calpain-1、PSD95、BDNF分别有较强的结合力。结论人参-黄精以2∶1的配比能更有效阻止SPS诱导的小鼠PTSD样行为,其作用可能与调控Calpain-1、PSD95、BDNF和GluN2B等靶标相关。 展开更多
关键词 人参 黄精 不同配比 PTSD 分子靶标 生物信息学
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2种云南特色小米辣果实成熟过程中代谢物比较分析
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作者 胡华冉 钟秋月 +4 位作者 杜磊 张芮豪 李卫芬 刘发万 桂敏 《热带作物学报》 北大核心 2025年第2期343-358,共16页
辣椒及其制品以其独特的风味深受各国人民喜爱,而代谢物质的组成及其含量对辣椒风味品质有重要影响。小米辣是云南区域性特色辣椒品种,因其营养成分丰富、辣味香浓深受消费者青睐。为了探明不同栽培种云南特色小米辣果实在成熟过程中代... 辣椒及其制品以其独特的风味深受各国人民喜爱,而代谢物质的组成及其含量对辣椒风味品质有重要影响。小米辣是云南区域性特色辣椒品种,因其营养成分丰富、辣味香浓深受消费者青睐。为了探明不同栽培种云南特色小米辣果实在成熟过程中代谢产物和代谢途径的异同,本研究以绿熟期和红熟期云南本地传统小米辣(Capsicum frutescens L.)和晶翠(C. baccatum L.)小米辣果实为研究对象,借助非靶向代谢组技术揭示2种小米辣果实在不同生育期的代谢物变化和代谢途径差异。结果表明:在云南小米辣中共鉴定出12类880个代谢产物,其中脂类、有机酸类占比最高,表明云南小米辣营养物质丰富,可以作为一种潜在的功能性食品原料。差异代谢物的种类、数量因生育期、品种差异出现显著不同,但小米辣红熟果较绿熟果的营养物质更丰富;2种栽培种相比,云南本地小米辣中的黄酮类物质较丰富,而晶翠中的氨基酸数量、种类更多。从不同比较组筛选出特有差异代谢物,黄酮类、甘油磷脂类、氨基酸类等物质可作为2种栽培种在不同生育期的潜在生物标志。KEGG富集分析发现包含了常见代谢物的代谢通路(脂质、氨基酸、糖类、碳水化合物、次生代谢产物、萜类和多酮类等),小米辣在2个生育期的关键代谢通路主要富集在甘油磷脂代谢通路、黄酮和黄酮醇生物合成、植物次生代谢产物的生物合成、苯丙素的生物合成,并找到不同比较组特有差异代谢通路。综上,2种小米辣果实代谢物种类、数量差异显著且独具特色,本研究结果为小米辣风味品质育种及后期采收策略提供数据支持。 展开更多
关键词 小米辣 不同生育期 非靶向代谢组 差异代谢物 代谢途径
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FDLIE-YOLO:频域增强的端到端低照度图像目标检测方法 被引量:1
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作者 李扬 李现国 +3 位作者 陈莲 杨清永 徐常余 徐晟 《红外与激光工程》 北大核心 2025年第1期256-268,共13页
针对低照度图像目标检测的挑战,提出一种端到端检测方法FDLIE-YOLO。首先,设计频域处理模块FDPB(Frequency Domain Processing Block),采用傅里叶变换提取全局信息,从而获取估计幅度分量,利用其与亮度的正相关关系,提升低光照图像质量,... 针对低照度图像目标检测的挑战,提出一种端到端检测方法FDLIE-YOLO。首先,设计频域处理模块FDPB(Frequency Domain Processing Block),采用傅里叶变换提取全局信息,从而获取估计幅度分量,利用其与亮度的正相关关系,提升低光照图像质量,进而构建频域低照度图像增强网络FDLIENet(Frequency Domain Low-light Image Enhancement Network)。然后,使用YOLOv8n进行目标检测,通过联合损失实现图像增强与目标检测的端到端训练。该损失引入马氏距离的幅度差异损失,以精准调整图像幅度,并用MPDIoU(Minimum Point Distance based IoU)损失取代YOLOv8n原有的回归损失,提高检测准确性。实验结果显示,FDLIENet在低照度环境下的图像增强表现显著,在LOLReal和ExDark数据集上的PSNR、SSIM和NIQE指标分别达到23.18 dB、0.858和3.98;FDLIEYOLO在ExDark数据集,平均精度均值mAP为80.6%,较当前主流端到端检测方法提高了1.1%~1.6%,且实时性好。 展开更多
关键词 低照度图像 目标检测 增强网络 频域处理 幅度差异损失 回归损失
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