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Utilization of Industrial Waste Slag as Aggregate in Concrete Applications by Adopting Taguchi’s Approach for Optimization 被引量:2
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作者 Mohammed Nadeem Arun D. Pofale 《Open Journal of Civil Engineering》 2012年第3期96-105,共10页
This paper presents result of an experimental investigation carried out to evaluate effects of replacing aggregates (coarse & fine) with that of Slag (Crystallized & Granular) which is an industrial waste by-p... This paper presents result of an experimental investigation carried out to evaluate effects of replacing aggregates (coarse & fine) with that of Slag (Crystallized & Granular) which is an industrial waste by-product on concrete strength properties by using Taguchi’s approach of optimization. Whole study was done in three phases, in the first phase natural coarse aggregate was replaced by crystallized slag coarse aggregate keeping fine aggregate (natural sand) common in all the mixes, in the second phase fine aggregate (natural sand) was replaced by granular slag keeping natural coarse aggregate common in all the mixes and in the third phase both the aggregates were replaced by crystallized & granular aggregates. The study concluded that compressive strength of concrete improved almost all the % replacements of normal crushed coarse aggregate with crystallized slag by 5% to 7%. In case of replacements of fine aggregate and both type of aggregates, the strength improvements were notably noticed at 30% to 50% replacement level. It could also be said that full substitution of slag aggregate with normal crushed coarse aggregate improved the flexure and split tensile strength by 6% to 8% at all replacements and in case of replacing fine aggregate & both the aggregates( Fine & coarse) with slag, the strength improvement was at 30% to 50% replacements. It is evident from the investigation that Taguchi approach for optimization helped in indentifying the factors affecting the final outcomes. Based on the overall observations, it could be recommended that Slag could be effectively utilized as coarse & fine aggregates in all concrete applications. 展开更多
关键词 COMPREssIVE Flexure and sPLIT TENsILE strength sLAG AGGREGATE taguchi’s approach
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Optimization of safflower oil transesterification using the Taguchi approach 被引量:2
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作者 N.Kumar S.K.Mohapatra +2 位作者 S.S.Ragit K.Kundu R.Karmakar 《Petroleum Science》 SCIE CAS CSCD 2017年第4期798-805,共8页
Biodiesel is an alternative renewable fuel which is produced by using biomass resources. Its physicochemical properties are close to those of the petroleum diesel fuel. This study highlights biodiesel production from ... Biodiesel is an alternative renewable fuel which is produced by using biomass resources. Its physicochemical properties are close to those of the petroleum diesel fuel. This study highlights biodiesel production from safflower seed oil. The main aim of this experimental work is to optimize the process parameters, namely the methanolto-oil molar ratio, catalyst concentration, reaction time and reaction temperature for biodiesel production. The Taguchi robust design approach was used with an L9 orthogonal array to analyze the influence of process factors on performance parameters. The results showed that the optimum yield of biodiesel was 93.8% with viscosity 5.60 c St, with a methanol-to-oil molar ratio of 4:1, catalyst concentration of 1.5 wt%, reaction time of 90 min and reaction temperature of 60 ℃. The catalyst concentration was found to be the most influencing parameter which contributed 51.1% and 50.8% of the total effect on the yield of biodiesel, Y;, and viscosity of biodiesel, Y;, respectively. 展开更多
关键词 ANOVA BIODIEsEL OPTIMIZATION taguchi approach TRANsEsTERIFICATION
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Optimization of PVD process parameter for coating AZ91D magnesium alloy by Taguchi grey approach 被引量:6
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作者 M.Sivapragash P.Kumaradhas +1 位作者 S.C.Vettivel B.Stanly Jones Retnam 《Journal of Magnesium and Alloys》 SCIE EI CAS 2018年第2期171-179,共9页
This study was an attempt made to explore the possibility of increasing the surface properties of the AZ91D magnesium alloy by applying ZrO_(2)coating using Physical Vapour Deposition(PVD-RF)sputtering process.In orde... This study was an attempt made to explore the possibility of increasing the surface properties of the AZ91D magnesium alloy by applying ZrO_(2)coating using Physical Vapour Deposition(PVD-RF)sputtering process.In order to improve the quality of the coating,the PVD process parameter with multiple performance characteristics was optimized by using the Taguchi grey approach.L 18 orthogonal array was selected for conducting the experiments.The proposed Taguchi grey method was find out the optimal process parameter for multiple performance characteristics.The optimal combination was attained at chamber pressure of 0.003 bar,argon gas in millibar and power input of 200 W.The validation experiment result shows an improvement in the micro hardness and surface finish.Also,the performance characterizations such as SEM,EDX,XRD,coating thickness,surface roughness and micro hardness were measured at optimal process parameter. 展开更多
关键词 PVD coating Mg alloy taguchi grey approach
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Investigation of ductile iron casting process parameters using Taguchi approach and response surface methodology 被引量:3
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作者 A. Johnson Santhosh A. R. Lakshmanan 《China Foundry》 SCIE 2016年第5期352-360,共9页
To find the optimized levels of various casting parameters in the ductile iron casting, various casting defects and the rejection rate were observed from a medium scale foundry. The controlled values of different cast... To find the optimized levels of various casting parameters in the ductile iron casting, various casting defects and the rejection rate were observed from a medium scale foundry. The controlled values of different casting parameters such as pouring temperature, inoculation, carbon equivalent, moisture content, green compression strength, permeability and mould hardness were selected. Three different melts of metal with 0.4wt.%, 0.6wt.%, and 0.8wt.% inoculation (Fe-Si-Mg alloy and post inoculant) were produced using a 1-ton capacity coreless medium frequency induction furnace. L-27 orthogonal array with 3-level settings were chosen for the analysis. Responses for each run were observed. The signal-to-noise (S/N) ratio for each run was calculated using the Taguchi approach, and the optimized levels of different casting parameters were identified based on the SIN ratio. The analysis of variance for the casting acceptance percentage concludes that inoculation is the most significant factor affecting the castings' quality with a contribution percentage of 44%; an increase in inoculation results in a significant improvement in acceptance percentage of ductile iron castings. The experiment results showed that with the optimized parameters, the rejection rate was reduced from 16.98% to 6.07%. 展开更多
关键词 optimized levels casting parameters s/N ratio taguchi approach ANOVA ‘F’-Test
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Specific energy optimization in sawing of rocks using Taguchi approach 被引量:2
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作者 Izzet Karakurt 《Journal of Central South University》 SCIE EI CAS 2014年第1期365-372,共8页
This work aims at selecting optimal operating variables to obtain the minimum specific energy(SE) in sawing of rocks.A particular granite was sampled and sawn by a fully automated circular diamond sawblades.The periph... This work aims at selecting optimal operating variables to obtain the minimum specific energy(SE) in sawing of rocks.A particular granite was sampled and sawn by a fully automated circular diamond sawblades.The peripheral speed,the traverse speed,the cut depth and the flow rate of cooling fluid were selected as the operating variables.Taguchi approach was adopted as a statistical design of experimental technique for optimization studies.The results were evaluated based on the analysis of variance and signal-to-noise ratio(S/N ratio).Statistically significant operating variables and their percentage contribution to the process were also determined.Additionally,a statistical model was developed to demonstrate the relationship between SE and operating variables using regression analysis and the model was then verified.It was found that the optimal combination of operating variables for minimum SE is the peripheral speed of 25 m/s,the traverse speed of 70 cm/min,the cut depth of 2 cm and the flow rate of cooling fluid of 100 mL/s.The cut depth and traverse speed were statistically determined as the significant operating variables affecting the SE,respectively.Furthermore,the regression model results reveal that the predictive model has a high applicability for practical applications. 展开更多
关键词 circular diamond sawblades GRANITE specific energy taguchi approach
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Optimization of Carburized UNS G10170 Steel Process Parameters Using Taguchi Approach and Response Surface Model (RSM) 被引量:1
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作者 Olawale Samuel Fatoba Olaitan Lukman Akanji Abiodun Samson Aasa 《Journal of Minerals and Materials Characterization and Engineering》 2014年第6期566-578,共13页
The utilization of carburizing materials in surface engineering has undergone many tremendous changes. Effective quality control is possible through carburizing the steel components under op-timal conditions. In this ... The utilization of carburizing materials in surface engineering has undergone many tremendous changes. Effective quality control is possible through carburizing the steel components under op-timal conditions. In this research work, process parameters like furnace temperature, soaking time and particle size of energizer were taken for optimization of carburized UNS-G10170 steel to yield maximum hardness using Taguchi’s design of experiment concepts and Response Surface Model. Nine experimental runs based on Taguchi’s L9 orthogonal array were performed;signal to noise (S/N) ratios, analysis of variance (ANOVA) and regression analysis were used with hardness as response variable. From the optimization and experimental analyses conducted, it was observed that furnace temperature, soaking time and particle size had significant influence in obtaining a better surface integrity. The optimal values obtained during the study optimization by Taguchi approach and Response Surface Model (RSM) were validated by confirmation experiments. 展开更多
关键词 ANOVA s/N Ratios taguchi Method HARDNEss RsM OPTIMIZATION
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China’s Approach to Labor Provisions in Free Trade Agreements:Evolution,Impact,and Framework
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作者 WU Wenfang HUANG Linhan JIANG Yu(Translated) 《The Journal of Human Rights》 2025年第2期341-369,共29页
Labor provisions have become a fundamental trade rule in regional and bilateral trade agreements.Although China’s legislation on pilot Free Trade Zones includes content related to labor protection,it primarily aligns... Labor provisions have become a fundamental trade rule in regional and bilateral trade agreements.Although China’s legislation on pilot Free Trade Zones includes content related to labor protection,it primarily aligns with labor indicators in“Doing Business”,the assessment of business situations issued by the World Bank.It differs from the labor rights protection focus emphasized in trade agreements.The latest strategic documents issued by the State Council of China have addressed this issue to fully achieve the goal of aligning Free Trade Zones with high-standard trade agreements.Building on the development of Free Trade Zone legislation and domestic labor law governance,China should proactively explore a tailored approach to labor provisions in Free Trade Agreements.In this approach,it should explicitly define the“baseline”and“ceiling”for labor provisions during negotiations and,within this framework,establish benchmarks for labor rights protection,enforcement mechanisms,and cross-border regulatory mechanisms suited to the specific conditions of the agreement parties. 展开更多
关键词 labor law governance pilot free trade zones free trade agreements labor standards China’s approach
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Brief on Language Oriented Approach(LOA)of Teaching Programming Skills
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作者 Bauminwood 《Journal of Contemporary Educational Research》 2025年第8期78-84,共7页
The study believes teaching is a communication and exchange process between teachers and students,and the quality of teaching depends on communication qualities,especially whether theories,ideas,and methods are accura... The study believes teaching is a communication and exchange process between teachers and students,and the quality of teaching depends on communication qualities,especially whether theories,ideas,and methods are accurately transmitted from teachers to students.In programming course teaching,there are losses of the original meaning of the English textbook after being translated into Chinese.In order to avoid the loss of original meaning,the study uses original English textbook for the software programming teaching.In the language choice for specific documentation and programming descriptions,the study emphasizes the choice of the inventor’s language.Based on practice,the study summarized the principle of the Language Oriented Approach of Teaching Programming Skills,and outlined the main points and structure of this approach,concluding the prerequisites for its use.Also,the categories of Language Oriented Approach are mentioned.The study shed light on attributing the use of AI,such as the emerging ChatGPT applications,to the Language Oriented Approach. 展开更多
关键词 Language Oriented approach of teaching Inventor’s Native Language Programming professional training The nature of ChatGPT application in teaching
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The Comparison and Contrast of Skopostheorie and Baker's Equivalence Translation Approach
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作者 李永秀 《海外英语》 2011年第7X期176-178,共3页
Equivalence can be said to be the central issue in translation although its different approaches have caused heated controversy.However,as early as the 1970s,the Skopostheorie emerged in Germany,and it seemed to chall... Equivalence can be said to be the central issue in translation although its different approaches have caused heated controversy.However,as early as the 1970s,the Skopostheorie emerged in Germany,and it seemed to challenge the equivalence theories.Although Nida and some linguistics raised some negative problems of this theory,it still rapidly became famous around the world,This article will mainly compare and analyse Skopostheorie and Baker's translation equivalence approach.First,it will give a simple overview of these two approaches.Second,it will discuss the relevant strengths and weaknesses of these two approaches in relation to their usage.Finally,it will discuss combining these two approaches in the same translation. 展开更多
关键词 COMPARIsON and CONTRAsT skopostheorie Baker’s EQUIVALENCE TRANsLATION approach
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Comparison of the modified Wiltse’s approach with spinal minimally invasive system and traditional approach for the therapy of thoracolumbar fracture 被引量:19
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作者 Jie Chang Jiang Cao +3 位作者 Ziyan Huang Boyao Wang Tao Sui Xiaojian Cao 《The Journal of Biomedical Research》 CAS CSCD 2020年第5期379-386,共8页
Thoracolumbar fractures are usually treated by open posterior pedicle screw fixation.However,this procedure involves massive paraspinal muscle stripping,inflicting surgical trauma,and prolonged X-ray exposure.In this ... Thoracolumbar fractures are usually treated by open posterior pedicle screw fixation.However,this procedure involves massive paraspinal muscle stripping,inflicting surgical trauma,and prolonged X-ray exposure.In this study,we observed 127 patients with single-segment injury thoracolumbar fractures.Thirty-six patients were treated by the modified Wiltse’s paraspinal approach with minimally invasive channel system,while 91 patients were treated via traditional posterior approach.Operation time,intraoperative blood loss,intraoperative fluoroscopy frequency,screw placement accuracy,visual analogue scale score,and Cobb’s angle of two groups were compared.The X-ray exposure times were notably reduced(4.2±1.6) in the new approach group(P<0.05).The pedicle screw placement accuracy and Cobb’s angle after surgery were similar in the two groups.We conclude that modified Wiltse’s paraspinal approach w ith spinal minimally invasive channel system surgery can significantly reduce the X-ray exposure times and is an alternative therapy for the thoracolumbar fracture. 展开更多
关键词 thoracolumbar fracture Wiltse’s paraspinal approach spinal minimally invasive channel system
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Description of two new species of Pseudoaliinostoc(Nostocales,Cyanobacteria)from China based on the polyphasic approach 被引量:4
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作者 Fangfang CAI Gongliang YU Renhui LI 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2022年第3期1233-1244,共12页
Two cyanobacterial strains CHAB5870 and CHAB5871 morphologically identifi ed as Nostoc-like species were isolated from different habitats in China,and they were phylogenetically and taxonomically characterized based o... Two cyanobacterial strains CHAB5870 and CHAB5871 morphologically identifi ed as Nostoc-like species were isolated from different habitats in China,and they were phylogenetically and taxonomically characterized based on a polyphasic approach combining morphological,ecological,and molecular data.In the 16S rRNA gene phylogeny inferred using maximum likelihood,maximum-parismony,and bayesian inference methods,these two strains clustered within the Pseudoaliinostoc clade.The 16S rRNA gene sequences of these two strains displayed≥95.5%and≤98%similarity to Pseudoaliinostoc species,which indicated them to represent new species of the genus Pseudoaliinostoc.Furthermore,the unique pattern of D1-D1′and Box-B helix of the 16S–23S rRNA internal transcribed spacer(ITS)secondary structure also revealed that two strains represented novel species.These results supported the establishment of two new Pseudoaliinostoc species with the name P.jiangxiense sp.nov.and P.yunnanense sp.nov. 展开更多
关键词 16s rRNA gene 16s–23s ITs new species morphology polyphasic approach TAXONOMY
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Comparison of six statistical approaches in the selection of appropriate fish growth models 被引量:7
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作者 朱立新 李丽芳 梁振林 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2009年第3期457-467,共11页
The performance of six statistical approaches,which can be used for selection of the best model to describe the growth of individual fish,was analyzed using simulated and real length-at-age data.The six approaches inc... The performance of six statistical approaches,which can be used for selection of the best model to describe the growth of individual fish,was analyzed using simulated and real length-at-age data.The six approaches include coefficient of determination(R2),adjusted coefficient of determination(adj.-R2),root mean squared error(RMSE),Akaike's information criterion(AIC),bias correction of AIC(AICc) and Bayesian information criterion(BIC).The simulation data were generated by five growth models with different numbers of parameters.Four sets of real data were taken from the literature.The parameters in each of the five growth models were estimated using the maximum likelihood method under the assumption of the additive error structure for the data.The best supported model by the data was identified using each of the six approaches.The results show that R2 and RMSE have the same properties and perform worst.The sample size has an effect on the performance of adj.-R2,AIC,AICc and BIC.Adj.-R2 does better in small samples than in large samples.AIC is not suitable to use in small samples and tends to select more complex model when the sample size becomes large.AICc and BIC have best performance in small and large sample cases,respectively.Use of AICc or BIC is recommended for selection of fish growth model according to the size of the length-at-age data. 展开更多
关键词 growth model model selection statistical approach Akalke's information criterion Bayesian information criterion
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A molecular mechanics approach for analyzing tensile nonlinear deformation behavior of single-walled carbon nanotubes 被引量:3
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作者 Yu Wang Daining Fang +1 位作者 Ai Kah Soh Bin Liu 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2007年第6期663-671,共9页
In this paper, by capturing the atomic information and reflecting the behaviour governed by the nonlinear potential function, an analytical molecular mechanics approach is proposed. A constitutive relation for single-... In this paper, by capturing the atomic information and reflecting the behaviour governed by the nonlinear potential function, an analytical molecular mechanics approach is proposed. A constitutive relation for single-walled carbon nanotubes (SWCNT's) is established to describe the nonlinear stress-strain curve of SWCNT's and to predict both the elastic properties and breaking strain of SWCNT's during tensile deformation. An analysis based on the virtual internal bond (VIB) model proposed by P. Zhang et al. is also presented for comparison. The results indicate that the proposed molecular mechanics approach is indeed an acceptable analytical method for analyzing the mechanical behavior of SWCNT's. 展开更多
关键词 Molecular mechanics approach Carbon nanotube Constitutive relation Young's modulus
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Hyperbaric oxygen therapy as a new treatment approach for Alzheimer's disease 被引量:5
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作者 Ronit Shapira Shai Efrati Uri Ashery 《Neural Regeneration Research》 SCIE CAS CSCD 2018年第5期817-818,共2页
Hyperbaric oxygen therapy as a new treatment approach for Alzheimer’s disease(AD):Alongside the increase in life expectancy,the prevalence of age-related disorders,such as neurodegenerative diseases,is on the rise... Hyperbaric oxygen therapy as a new treatment approach for Alzheimer’s disease(AD):Alongside the increase in life expectancy,the prevalence of age-related disorders,such as neurodegenerative diseases,is on the rise.For example,AD,the most common form of dementia in the elderly,accounts for 60–80%of all dementia cases. 展开更多
关键词 Hyperbaric oxygen therapy as a new treatment approach for Alzheimer’s disease AD
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Combining ability and gene action studies for yield and fibre traits in Gossypium arboreum using Griffings numerical and Haymans graphical approach 被引量:1
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作者 SUKRUTHA Bhimireddy RAJESWARI Sivakami +3 位作者 PREMALATHA N. BOOPATHI Narayana Manikanda THIRUKUMARAN K. MANIVANNAN A. 《Journal of Cotton Research》 CAS 2023年第3期141-156,共16页
Background For the purpose of utilising hybrid vigour to produce possible hybrids with a suitable level of stability,the knowledge of gene activity and combining ability is a crucial prerequisite before choosing desir... Background For the purpose of utilising hybrid vigour to produce possible hybrids with a suitable level of stability,the knowledge of gene activity and combining ability is a crucial prerequisite before choosing desirable parents.The present study was carried out with six parents crossed in full diallel fashion and generated 30 F1 hybrids.These hybrids were evaluated in two replications in Randomized Block Design at Department of Cotton,TNAU for combining ability and gene action.Diallel analysis was carried out according to Griffing’s method-I(parents + F_(1) + reciprocals) and model-I and Hayman’s graphical approach by using INDOSTAT software.Results Analysis of variance for combining ability indicated that mean square values of GCA,SCA and reciprocals were highly significant for all the traits except for the uniformity index.RG763 and K12 showed highly positively significant GCA effects for most of the yield traits while PA838 and K12 for fibre quality traits,so they were found as best general combiners.PAIG379 × K12 and PDB29 × K12 for yield traits,and PDB29 × PA838,RG763 × PA838,and CNA1007 × RG763 cross combinations for fibre quality traits could be recommended for future breeding programms.Conclusion The results of both Griffing’s and Hayman’s approaches showed that non-additive gene action predominates as SCA variance was bigger than GCA variance,so heterosis breeding is thought to be a more fruitful option for enhancing GCA of many traits. 展开更多
关键词 Gene action Combining ability Diallel analysis Hayman’s approach Griffing’s approach Vr-Wr graph Desi cotton
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New approaches for prevention and treatment of Alzheimer's disease:a fascinating challenge 被引量:4
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作者 Luca Piemontese 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第3期405-406,共2页
The prevention and treatment of neurodegenerative diseases is the new challenge for pharmaceutical industry,but also for public institutions,physicians,patients,and their families.The spread of these pathologies is,in... The prevention and treatment of neurodegenerative diseases is the new challenge for pharmaceutical industry,but also for public institutions,physicians,patients,and their families.The spread of these pathologies is,in fact,a real social problem,especially in the Western Countries where the population age is increasing and chronic diseases are more and more common. 展开更多
关键词 PPARs New approaches for prevention and treatment of Alzheimer’s disease:a fascinating challenge
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Adapting communicative language teaching approach to China's context 被引量:3
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作者 YE Jin 《Sino-US English Teaching》 2007年第10期29-33,共5页
The issue on which this essay focuses is how to adapt the Communicative Language Teaching (CLT) Approach to China's context. With the recent accession to the WTO, the long-awaited Olympic games in Beijing, China ha... The issue on which this essay focuses is how to adapt the Communicative Language Teaching (CLT) Approach to China's context. With the recent accession to the WTO, the long-awaited Olympic games in Beijing, China has made learning English a national priority. It is very important and necessary to research on how to adapt CLT flexibly and appropriately to China's context if most Chinese English learners are to gain a good grasp of oral English, and if specialist learning is to be achieved by those who need English for business and academic purposes. Therefore this essay is structured as follows: First, analyzing the different types of English teaching methods in China and then focusing on the CLT Method. By analyzing and contrasting these English teaching methods, the need to change the current English teaching methods in China will be discovered. Finally, it explains the problems of adopting the more modem CLT Approach and gives suggestions on how it may best be adapted to the Chinese context. 展开更多
关键词 CLT approach China's context English teaching
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Tribological Behaviour of Aluminium/Alumina/Graphite Hybrid Metal Matrix Composite Using Taguchi’s Techniques 被引量:2
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作者 N. Radhika R. Subramanian S. Venkat Prasat 《Journal of Minerals and Materials Characterization and Engineering》 2011年第5期427-443,共17页
Tribological behaviour of aluminium alloy (Al-Si10Mg) reinforced with alumina (9%) and graphite (3%) fabricated by stir casting process was investigated. The wear and frictional properties of the hybrid metal matrix c... Tribological behaviour of aluminium alloy (Al-Si10Mg) reinforced with alumina (9%) and graphite (3%) fabricated by stir casting process was investigated. The wear and frictional properties of the hybrid metal matrix composites was studied by performing dry sliding wear test using a pin-on-disc wear tester. Experiments were conducted based on the plan of experiments generated through Taguchi’s technique. A L27 Orthogonal array was selected for analysis of the data. Investigation to find the influence of applied load, sliding speed and sliding distance on wear rate, as well as the coefficient of friction during wearing process was carried out using ANOVA and regression equations for each response were developed. Objective of the model was chosen as ‘smaller the better’ characteristics to analyse the dry sliding wear resistance. Results show that sliding distance has the highest influence followed by load and sliding speed. Finally, confirmation tests were carried out to verify the experimental results and Scanning Electron Microscopic studies were done on the wear surfaces. 展开更多
关键词 Metal Matrix Composites sTIR CAsTING taguchi’s TECHNIQUEs ORTHOGONAL array Analysis of variance wear behaviour.
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A direct probabilistic approach to solve state equations for nonlinear systems under random excitation 被引量:1
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作者 Zheng Lv Zhiping Qiu 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2016年第5期941-958,共18页
In this paper, a direct probabilistic approach(DPA) is presented to formulate and solve moment equations for nonlinear systems excited by environmental loads that can be either a stationary or nonstationary random p... In this paper, a direct probabilistic approach(DPA) is presented to formulate and solve moment equations for nonlinear systems excited by environmental loads that can be either a stationary or nonstationary random process.The proposed method has the advantage of obtaining the response's moments directly from the initial conditions and statistical characteristics of the corresponding external excitations. First, the response's moment equations are directly derived based on a DPA, which is completely independent of the It?/filtering approach since no specific assumptions regarding the correlation structure of excitation are made.By solving them under Gaussian closure, the response's moments can be obtained. Subsequently, a multiscale algorithm for the numerical solution of moment equations is exploited to improve computational efficiency and avoid much wall-clock time. Finally, a comparison of the results with Monte Carlo(MC) simulation gives good agreement.Furthermore, the advantage of the multiscale algorithm in terms of efficiency is also demonstrated by an engineering example. 展开更多
关键词 Direct probabilistic approach Nonlinear dynamic system Nonstationary random process Response’s moments Multiscale algorithm
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Shifting balance from neurodegeneration to regeneration of the brain: a novel therapeutic approach to Alzheimer's disease and related neurodegenerative conditions 被引量:3
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作者 Khalid Iqbal Syed Faraz Kazim +1 位作者 Silvia Bolognin Julie Blanchard 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第16期1518-1519,共2页
Neurodegeneration is one of the biggest public health problems in modern society. Age-associated neurodegeneration, which is accelerated several-fold in Alzheimer's disease (AD) alone, is not only an enormous socia... Neurodegeneration is one of the biggest public health problems in modern society. Age-associated neurodegeneration, which is accelerated several-fold in Alzheimer's disease (AD) alone, is not only an enormous social and economic burden to the affected in- dividuals and their families, but is also a great scientific challenge. Currently 25-35 million people worldwide suffer from AD, the single largest cause of dementia in middle- to old-aged individuals. These numbers are projected to triple by 2050 if no treatment to prevent or reverse AD is developed. 展开更多
关键词 a novel therapeutic approach to Alzheimer’s disease and related neurodegenerative conditions shifting balance from neurodegeneration to regeneration of the brain AD
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