目的:比较米拉贝隆与舍尼亭治疗TURP术后膀胱痉挛的安全性与有效性。方法:回顾性收集TURP术后因膀胱痉挛使用米拉贝隆或舍尼亭的患者临床数据各45例,评估米拉贝隆与舍尼亭的有效性以及安全性。结果:米拉贝隆组总有效率为93.33%,高于舍...目的:比较米拉贝隆与舍尼亭治疗TURP术后膀胱痉挛的安全性与有效性。方法:回顾性收集TURP术后因膀胱痉挛使用米拉贝隆或舍尼亭的患者临床数据各45例,评估米拉贝隆与舍尼亭的有效性以及安全性。结果:米拉贝隆组总有效率为93.33%,高于舍尼亭组的73.33%,差异具有统计学意义(P Objective: To compare the safety and efficacy of mirabegron and tolterodine in the treatment of bladder spasm after transurethral resection of the prostate (TURP). Methods: The clinical data of 45 patients who used mirabegron and 45 patients who used tolterodine for bladder spasm after TURP were retrospectively collected to evaluate the efficacy and safety of mirabegron and tolterodine. Results: The total effective rate of the mirabegron group was 93.33%, which was higher than that of the tolterodine group (73.33%), and the difference was statistically significant (P < 0.05). The rate of requiring additional analgesic drugs in the mirabegron group was 6.67%, which was lower than that in the tolterodine group (26.7%). The incidence of adverse reactions such as dry eyes, dry mouth, and constipation in the tolterodine group was higher than that in the mirabegron group (40% vs 12%). Six patients in the tolterodine group developed urinary retention after catheter removal, while no acute urinary retention occurred in the mirabegron group. Conclusion: The efficacy and safety of mirabegron in the treatment of bladder spasm after TURP seem to be slightly higher than those of tolterodine, and it has good clinical applicability.展开更多
目的:探讨经尿道前列腺电切术(trans-urethral resection of prostate,TURP)后排尿困难的病因及处理。方法:回顾性分析22例TURP术后出现排尿困难患者的临床资料及治疗方法。结果:术后发生腺体及异物残留3例,尿道狭窄5例,膀胱颈挛缩和逼...目的:探讨经尿道前列腺电切术(trans-urethral resection of prostate,TURP)后排尿困难的病因及处理。方法:回顾性分析22例TURP术后出现排尿困难患者的临床资料及治疗方法。结果:术后发生腺体及异物残留3例,尿道狭窄5例,膀胱颈挛缩和逼尿肌无力各7例,均经治疗后恢复。结论:腺体残留、尿道狭窄、膀胱颈挛缩、逼尿肌无力是TURP术后排尿困难的主要原因。正确的术前诊断及术中、术后处理是预防TURP术后发生排尿困难的关键。展开更多
目的探讨经尿道前列腺切除术(transurethral resection of prostate,TURP)术后尿道狭窄的预防及诊治策略。方法回顾性分析2006-2010年本科104例TURP术后尿道狭窄患者临床资料,总结患者术后临床症状、发病时间、狭窄发生部位及疗效,结合...目的探讨经尿道前列腺切除术(transurethral resection of prostate,TURP)术后尿道狭窄的预防及诊治策略。方法回顾性分析2006-2010年本科104例TURP术后尿道狭窄患者临床资料,总结患者术后临床症状、发病时间、狭窄发生部位及疗效,结合临床检查情况进行分析。结果前列腺增生患者TURP术后尿道狭窄发生率为(4.44%,104/2 341);TURP术后尿道狭窄多发生于术后1年内,术后4～6个月为本组尿道狭窄发生高发期(41.35%,43/104);TURP术后尿道狭窄最常见狭窄部位为膜部尿道(35.58%,37/104),其次为尿道外口(21.15%,22/104)、膀胱颈(18.27%,19/104)及悬垂部(15.38%,16/104)。结论加强手术操作技能训练、尿管护理及充分润滑有助于预防TURP术后尿道狭窄的发生,治疗需要根据尿道狭窄部位及程度进行选择。展开更多
目的探讨经尿道前列腺切除术(transurethral resection of prostate,TURP)在晚期前列腺癌治疗中的作用。方法研究组晚期前列腺癌68例予TURP加间歇内分泌治疗,对照组晚期前列腺癌20例予单纯间歇内分泌治疗,对比研究组与对照组术后1月、...目的探讨经尿道前列腺切除术(transurethral resection of prostate,TURP)在晚期前列腺癌治疗中的作用。方法研究组晚期前列腺癌68例予TURP加间歇内分泌治疗,对照组晚期前列腺癌20例予单纯间歇内分泌治疗,对比研究组与对照组术后1月、半年、1年、3年国际前列腺症状评分、最大尿流率、前列腺特异性抗原、疾病进展率、肿瘤相关病死率。结果研究组TURP术后1月、半年与对照组相比国际前列腺症状评分、最大尿流率有显著改善(P<0.01)。两组疾病进展率及肿瘤相关病死率差异无统计学意义(P>0.05)。结论 TURP加间歇内分泌治疗能迅速解除前列腺癌所致膀胱出口梗阻症状,明显改善患者生存质量,且不会加快疾病进展率及增加肿瘤相关病死率。展开更多
文摘目的:比较米拉贝隆与舍尼亭治疗TURP术后膀胱痉挛的安全性与有效性。方法:回顾性收集TURP术后因膀胱痉挛使用米拉贝隆或舍尼亭的患者临床数据各45例,评估米拉贝隆与舍尼亭的有效性以及安全性。结果:米拉贝隆组总有效率为93.33%,高于舍尼亭组的73.33%,差异具有统计学意义(P Objective: To compare the safety and efficacy of mirabegron and tolterodine in the treatment of bladder spasm after transurethral resection of the prostate (TURP). Methods: The clinical data of 45 patients who used mirabegron and 45 patients who used tolterodine for bladder spasm after TURP were retrospectively collected to evaluate the efficacy and safety of mirabegron and tolterodine. Results: The total effective rate of the mirabegron group was 93.33%, which was higher than that of the tolterodine group (73.33%), and the difference was statistically significant (P < 0.05). The rate of requiring additional analgesic drugs in the mirabegron group was 6.67%, which was lower than that in the tolterodine group (26.7%). The incidence of adverse reactions such as dry eyes, dry mouth, and constipation in the tolterodine group was higher than that in the mirabegron group (40% vs 12%). Six patients in the tolterodine group developed urinary retention after catheter removal, while no acute urinary retention occurred in the mirabegron group. Conclusion: The efficacy and safety of mirabegron in the treatment of bladder spasm after TURP seem to be slightly higher than those of tolterodine, and it has good clinical applicability.
文摘目的:探讨经尿道前列腺电切术(trans-urethral resection of prostate,TURP)后排尿困难的病因及处理。方法:回顾性分析22例TURP术后出现排尿困难患者的临床资料及治疗方法。结果:术后发生腺体及异物残留3例,尿道狭窄5例,膀胱颈挛缩和逼尿肌无力各7例,均经治疗后恢复。结论:腺体残留、尿道狭窄、膀胱颈挛缩、逼尿肌无力是TURP术后排尿困难的主要原因。正确的术前诊断及术中、术后处理是预防TURP术后发生排尿困难的关键。
文摘目的探讨经尿道前列腺切除术(transurethral resection of prostate,TURP)术后尿道狭窄的预防及诊治策略。方法回顾性分析2006-2010年本科104例TURP术后尿道狭窄患者临床资料,总结患者术后临床症状、发病时间、狭窄发生部位及疗效,结合临床检查情况进行分析。结果前列腺增生患者TURP术后尿道狭窄发生率为(4.44%,104/2 341);TURP术后尿道狭窄多发生于术后1年内,术后4～6个月为本组尿道狭窄发生高发期(41.35%,43/104);TURP术后尿道狭窄最常见狭窄部位为膜部尿道(35.58%,37/104),其次为尿道外口(21.15%,22/104)、膀胱颈(18.27%,19/104)及悬垂部(15.38%,16/104)。结论加强手术操作技能训练、尿管护理及充分润滑有助于预防TURP术后尿道狭窄的发生,治疗需要根据尿道狭窄部位及程度进行选择。
文摘目的探讨经尿道前列腺切除术(transurethral resection of prostate,TURP)在晚期前列腺癌治疗中的作用。方法研究组晚期前列腺癌68例予TURP加间歇内分泌治疗,对照组晚期前列腺癌20例予单纯间歇内分泌治疗,对比研究组与对照组术后1月、半年、1年、3年国际前列腺症状评分、最大尿流率、前列腺特异性抗原、疾病进展率、肿瘤相关病死率。结果研究组TURP术后1月、半年与对照组相比国际前列腺症状评分、最大尿流率有显著改善(P<0.01)。两组疾病进展率及肿瘤相关病死率差异无统计学意义(P>0.05)。结论 TURP加间歇内分泌治疗能迅速解除前列腺癌所致膀胱出口梗阻症状,明显改善患者生存质量,且不会加快疾病进展率及增加肿瘤相关病死率。
