Gastric cancer(GC)is the fifth most common malignancy and the fourth leading cause of cancer-related death worldwide,with China bearing nearly half of the global burden[1,2].Most patients are diagnosed at stage Ⅲ–Ⅳ...Gastric cancer(GC)is the fifth most common malignancy and the fourth leading cause of cancer-related death worldwide,with China bearing nearly half of the global burden[1,2].Most patients are diagnosed at stage Ⅲ–Ⅳ,and despite perioperative therapy plus D2 gastrectomy being the standard of care,long-term survival remains poor[3,4].展开更多
基金supported by the National Key Research and Development Program of China(2021YFA0910100 and 2022YFC2504602)Healthy Zhejiang One Million People Cohort(K-20230085)+9 种基金National Natural Science Foundation of China(82304946,82241230,T2125002,82341007,82304946,82473489,and 82573745)Zhejiang gastrointestinal cancer Clinical Medical Research Center(2022E50006)Medical Science and Technology Project of Zhejiang Province(WKJ-ZJ-2323)Beijing Natural Science Foundation(Z220014)Natural Science Foundation of Zhejiang Province(LR21H280001,LBZ22H160002,LBD24H290001,and LMS25H160006)Science and Technology Projects of Zhejiang Province(2019C03049)Program of Zhejiang Provincial TCM Sci-tech Plan(2018ZY006 and 2020ZZ005)Science and Technology Projects of Zhejiang Province(2022KY684)Program of Zhejiang Provincial TCM Sci-tech Plan(2022ZQ020)the New Cornerstone Science Foundation through the XPLORER PRIZE.
文摘Gastric cancer(GC)is the fifth most common malignancy and the fourth leading cause of cancer-related death worldwide,with China bearing nearly half of the global burden[1,2].Most patients are diagnosed at stage Ⅲ–Ⅳ,and despite perioperative therapy plus D2 gastrectomy being the standard of care,long-term survival remains poor[3,4].