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Comprehensive single-cell profiling uncovers TsMHC-Ⅱ expression predicting response to neoadjuvant immunotherapy in gastric cancer
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作者 Zhiyuan Xu Zhichun Tang +18 位作者 Simeng Hu Litao Yang Jingli Xu Pengfei Yu Yian Du Yanqiang Zhang Jiahui Chen Xiaoxiao Wu Siwei Pan ShengJie Zhang Ling Huang Qing Wei Ruolan Zhang Wujie Chen Haibin Wei Wei Sun Can Hu Fan Bai Xiangdong Cheng 《Science Bulletin》 2026年第4期727-731,共5页
Gastric cancer(GC)is the fifth most common malignancy and the fourth leading cause of cancer-related death worldwide,with China bearing nearly half of the global burden[1,2].Most patients are diagnosed at stage Ⅲ–Ⅳ... Gastric cancer(GC)is the fifth most common malignancy and the fourth leading cause of cancer-related death worldwide,with China bearing nearly half of the global burden[1,2].Most patients are diagnosed at stage Ⅲ–Ⅳ,and despite perioperative therapy plus D2 gastrectomy being the standard of care,long-term survival remains poor[3,4]. 展开更多
关键词 gastric cancer gc perioperative therapy neoadjuvant immunotherapy comprehensive single cell profiling gastric cancer long term survival tsmhc II expression d gastrectomy
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