Background:Cyperi Rhizoma,derived from Cyperus rotundus L.,is a widely used medicinal herb in traditional Chinese medicine(TCM),with Shandong Province recognized as its geo-authentic habitat.However,the quality of Cyp...Background:Cyperi Rhizoma,derived from Cyperus rotundus L.,is a widely used medicinal herb in traditional Chinese medicine(TCM),with Shandong Province recognized as its geo-authentic habitat.However,the quality of Cyperi Rhizoma varies significantly across different regions,potentially influencing its therapeutic efficacy.This study investigates the influence of geographic origin on the chemical composition and overall quality of Cyperi Rhizoma.Methods:A comprehensive approach,including traditional quality assessment,GC-MS(g as c hromatography-m ass s pectrometry),RP-HPLC(r everse p hase h igh-p erformance l iquid c hromatography),and FT-IR(f ourier t ransform i nfrared s pectroscopy)techniques,was employed to analyze Cyperi Rhizoma samples from Shandong Province.These methods examined the physical appearance,chemical profile,and content variations,particularly focusing onα-cyperone.Results:Traditional quality assessments revealed noticeable differences in the external characteristics of the samples.GC-MS analysis identified a variety of unique chemical constituents,while RP-HPLC and FT-IR showed significant variations inα-cyperone content,with higher levels found in Shandong samples.Conclusion:These results demonstrate that geographic origin is a critical determinant of Cyperi Rhizoma quality,with Shandong specimens exhibiting superiorα-cyperone levels and characteristic phytochemical profiles.This validates the geo-authenticity concept in TCM and provides actionable data for developing evidence-based quality standards,suggesting that provenance should be prioritized in medicinal material selection and pharmacopeial specifications.展开更多
The global prevalence of metabolic-associated fatty liver disease(MAFLD)is on the rise,seriously threatening human health.Currently,no specific approved drugs are available for its treatment.This paper reviews the pat...The global prevalence of metabolic-associated fatty liver disease(MAFLD)is on the rise,seriously threatening human health.Currently,no specific approved drugs are available for its treatment.This paper reviews the pathogenesis of MAFLD,covering aspects like lipid accumulation and insulin resistance,oxidative stress,endoplasmic reticulum stress(ERS),lipotoxicity-induced hepatocyte damage,and fibrosis.It also elaborates on multiple treatment approaches for MAFLD,including metabolic regulation,improvement of the gut-liver axis interaction,modulation of immune and inflammatory pathways,enhancement of the adipose tissue-liver interaction,alleviation of fibrosis,prevention of hepatocyte injury,and traditional Chinese medicine(TCM)external therapies.Additionally,natural product research advancements,individual Chinese medicine components,and mixed herbal formulas for MAFLD treatment is provided.Many natural products and traditional Chinese medicines exhibit favorable effects in regulating lipid metabolism,anti-inflammation,and anti-oxidation,offering new directions and potential drug options for MAFLD treatment.This is expected to provide a reference for future clinical treatment and drug development.展开更多
Currently,the number of patients with myopia is increasing rapidly across the globe.Traditional Chinese medicine(TCM),with its long history and rich experience,has shown promise in effectively managing and treating th...Currently,the number of patients with myopia is increasing rapidly across the globe.Traditional Chinese medicine(TCM),with its long history and rich experience,has shown promise in effectively managing and treating this condition.Nevertheless,considering the vast amount of research that is currently being conducted,focusing on the utilization of TCM in the management of myopia,there is an urgent requirement for a thorough and comprehensive review.The review would serve to clarify the practical applications of TCM within this specific field,and it would also aim to elucidate the underlying mechanisms that are at play,providing a deeper understanding of how TCM principles can be effectively integrated into modern medical practices.Here,some modern medical pathogenesis of myopia and appropriate TCM techniques studies are summarized in the prevention and treatment of myopia.Further,we discussed the potential mechanisms and the future research directions of TCM against myopia.Identifying these mechanisms is crucial for understanding how TCM can be effectively utilized in this context.The combination of various TCM methods or the combination of traditional Chinese and Western medicine is of great significance for the prevention and control of myopia in the future.展开更多
Chemotherapy-induced diarrhea(CID)is a major concern for cancer patients and is associated with significant morbidity and mortality.Currently,the clinical management of CID is limited.The utilization of antidiarrheal ...Chemotherapy-induced diarrhea(CID)is a major concern for cancer patients and is associated with significant morbidity and mortality.Currently,the clinical management of CID is limited.The utilization of antidiarrheal medications,such as loperamide and octreotide,is relatively limited because of their unsatisfactory efficacy and adverse effects.In recent years,traditional Chinese medicine(TCM)has attracted great interest because of its beneficial effect in treating CID,which has multitarget and low-toxicity therapeutic characteristics.TCM exhibits remarkable therapeutic potential in the prevention and treatment of CID.It can alleviate and treat CID by regulating chemical drug metabolism,improving the integrity of the intestinal barrier,stimulating proliferation while suppressing the apoptosis of intestinal epithelial cells,ameliorating oxidative stress and inflammation and regulating bile acids and aquaporins.However,large-scale,randomized,double-blind clinical trials of TCM for the treatment of CID are lacking,and most preclinical experiments have not been translated to clinical trials.Accordingly,this review highlights the clinical efficacy and molecular mechanisms of TCM against CID via PubMed,Web of Science and China National Knowledge Infrastructure and proposes that future research on TCM against CID should focus on strengthening the connection from bench to bed,which may help to comprehensively evaluate the therapeutic potential of TCM against CID.展开更多
Traditional Medicine(TM),particularly Traditional Chinese Medicine(TCM),is an indispensable component of the global healthcare system,offering unique insights to modern medical science.Clinical efficacy is the bedrock...Traditional Medicine(TM),particularly Traditional Chinese Medicine(TCM),is an indispensable component of the global healthcare system,offering unique insights to modern medical science.Clinical efficacy is the bedrock for the inheritance and development of TM.To meet the growing demand for high-quality healthcare,it is imperative to integrate TM with modern technology to address the issue of insufficient evidence for the efficacy of TM.展开更多
Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developme...Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.展开更多
Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developme...Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.展开更多
Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developme...Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.展开更多
Traditional Chinese medicines(TCMs)have been used for centuries to treat and manage various diseases.However,their effective delivery to targeted sites may be a major challenge due to their poor water solubility,low b...Traditional Chinese medicines(TCMs)have been used for centuries to treat and manage various diseases.However,their effective delivery to targeted sites may be a major challenge due to their poor water solubility,low bio-availability,and potential toxicity.Nanocarriers,such as liposomes,polymeric nanoparticles,inorganic nanoparticles,and organic/inorganic nanohybrids based on active constituents from TCMs have been extensively studied as a promising strategy to improve the delivery of active constituents from TCMs to achieve a higher therapeutic effect with fewer side effects compared to conventional formulations.This article summarizes the recent progress in nanocarrier-based delivery systems.Nanotechnology can broaden the scope of applications of traditional Chinese medicine.The concept of nano-traditional Chinese medicine(nano-TCM)is introduced,and the progress of nanomedicine,the advantages,and the development direction of nano-TCM are reviewed,providing new ideas for the development of nano-TCM.展开更多
Objective:To analyze the application value of prescription management of traditional Chinese medicine formula granules in reducing unreasonable prescriptions.Methods:From January to June 2024,before improving prescrip...Objective:To analyze the application value of prescription management of traditional Chinese medicine formula granules in reducing unreasonable prescriptions.Methods:From January to June 2024,before improving prescription management strategies,118 patients treated with traditional Chinese medicine formula granules were included in the control group.From July to December 2024,after improving prescription management strategies,118 patients treated with traditional Chinese medicine formula granules were included in the observation group.The unqualified prescription rate,incidence of adverse reactions,complaint rate,and satisfaction were compared.Results:The unqualified prescription rate of traditional Chinese medicine formula granules in the observation group was lower than that in the control group(P<0.05);the incidence of adverse reactions and patient complaint rate of traditional Chinese medicine formula granules in the observation group were lower than those in the control group(P<0.05);the satisfaction of traditional Chinese medicine formula granules in the observation group was higher than that in the control group(P<0.05).Conclusion:Improving the prescription management strategy of traditional Chinese medicine formula granules can reduce the unqualified prescription rate and the incidence of adverse drug reactions,reduce patient complaints,and is conducive to improving patient satisfaction.展开更多
In the dynamic landscape of modern healthcare and precision medicine,the digital revolution is reshaping medical industries at an unprecedented pace,and traditional Chinese medicine(TCM)is no exception[1-4].The paper...In the dynamic landscape of modern healthcare and precision medicine,the digital revolution is reshaping medical industries at an unprecedented pace,and traditional Chinese medicine(TCM)is no exception[1-4].The paper“From digits towards digitization:the past,present,and future of traditional Chinese medicine”by Academician&TCM National Master Qi WANG(王琦).展开更多
Modern western medicine typically focuses on treating specific symptoms or diseases,and traditional Chinese medicine(TCM)emphasizes the interconnections of the body’s various systems under external environment and ta...Modern western medicine typically focuses on treating specific symptoms or diseases,and traditional Chinese medicine(TCM)emphasizes the interconnections of the body’s various systems under external environment and takes a holistic approach to preventing and treating diseases.Phenomics was initially introduced to the field of TCM in 2008 as a new discipline that studies the laws of integrated and dynamic changes of human clinical phenomes under the scope of the theories and practices of TCM based on phenomics.While TCM Phenomics 1.0 has initially established a clinical phenomic system centered on Zhenghou(a TCM definition of clinical phenome),bottlenecks remain in data standardization,mechanistic interpretation,and precision intervention.Here,we systematically elaborates on the theoretical foundations,technical pathways,and future challenges of integrating digital medicine with TCM phenomics under the framework of“TCM phenomics 2.0”,which is supported by digital medicine technologies such as artificial intelligence,wearable devices,medical digital twins,and multi-omics integration.This framework aims to construct a closed-loop system of“Zhenghou–Phenome–Mechanism–Intervention”and to enable the digitization,standardization,and precision of disease diagnosis and treatment.The integration of digital medicine and TCM phenomics not only promotes the modernization and scientific transformation of TCM theory and practice but also offers new paradigms for precision medicine.In practice,digital tools facilitate multi-source clinical data acquisition and standardization,while AI and big data algorithms help reveal the correlations between clinical Zhenghou phenomes and molecular mechanisms,thereby improving scientific rigor in diagnosis,efficacy evaluation,and personalized intervention.Nevertheless,challenges persist,including data quality and standardization issues,shortage of interdisciplinary talents,and insufficiency of ethical and legal regulations.Future development requires establishing national data-sharing platforms,strengthening international collaboration,fostering interdisciplinary professionals,and improving ethical and legal frameworks.Ultimately,this approach seeks to build a new disease identification and classification system centered on phenomes and to achieve the inheritance,innovation,and modernization of TCM diagnostic and therapeutic patterns.展开更多
Insect-derived traditional Chinese medicine(TCM)constitutes an essential component of TCM,with the earliest records found in“52 Bingfang”(Prescriptions of fifty-two diseases,which is one of the earliest Chinese medi...Insect-derived traditional Chinese medicine(TCM)constitutes an essential component of TCM,with the earliest records found in“52 Bingfang”(Prescriptions of fifty-two diseases,which is one of the earliest Chinese medical prescriptions).展开更多
Traditional medicine in Myanmar has a long history,combining the local natural environment,culture,and religious beliefs to form a unique medical system.This article adopts the method of literature research,focusing o...Traditional medicine in Myanmar has a long history,combining the local natural environment,culture,and religious beliefs to form a unique medical system.This article adopts the method of literature research,focusing on the existing book“Milestones of Traditional Medicine in Myanmar”,and reviewing existing literature to analyze historical and contemporary sources.Elaborate on the question of how the history of traditional medicine in Myanmar originated and has continued to develop until now.These histories have proven that traditional medicine in Myanmar,despite facing numerous obstacles,has always been used by the people of Myanmar and has unique value,which deserves our continued attention and inheritance.展开更多
This review highlights the therapeutic qualities of crustaceans such as crabs,shrimps,lobsters,and similar species that have historically been utilized for promoting human health.This study is particularly valuable as...This review highlights the therapeutic qualities of crustaceans such as crabs,shrimps,lobsters,and similar species that have historically been utilized for promoting human health.This study is particularly valuable as our reliance on synthetic medications and chemicals for maintaining good health increases,often leading to numerous side effects.Thus,there is a pressing need to explore alternative and natural solutions that can enhance general well-being and avert illnesses.Crustaceans were found to have numerous compounds that possess qualities such as fighting microbial pathogens(antimicrobial),diminishing inflammation(anti-inflammatory),exhibiting antioxidant properties,and regulating the immune system(immuno-modulatory),making them helpful in addressing various health issues.This review highlights 25 species of crustaceans for having multiple exceptional benefits to human health.A crucial aspect of this study relied on ancient Vedic medical manuscripts,from which data was gathered regarding the types of crustaceans and their applications for preserving health.We collected data that was determined to uphold these conventional theories.The key findings of the study also include the versatile applications of multiple compounds that can be extracted from crustacean byproducts like their shell wastes.The major compounds are Chitin and Chitosan being greatly utilized in fields like agriculture,cosmetology,in medical sciences for tissue regeneration and drug delivery,paper and textile industry.Compounds like Astaxanthin were observed with positive cardiovascular effect and antioxidant properties while Glucosamine,Chondroitin and Taurine were found to be essential components of bio-metabolic pathways and various bio-synthesizing processes inside human body.Therefore,the research highlights the important contribution of crustaceans in multiple sectors and also points out their economic value.This systematic literature review seeks to serve as a resource for researchers,healthcare providers,and pharmaceutical professionals who utilize insights regarding crustaceans and their beneficial byproducts for sustainable applications in their respective areas.展开更多
Traditional Chinese medicine (TCM) with its millenniaold wisdom rooted in the principles of holistic Yin-Yang balance and “Bianzheng Lunzhi”[辨证论治, Zhenghou(证候) differentiation and treatment], has long offered ...Traditional Chinese medicine (TCM) with its millenniaold wisdom rooted in the principles of holistic Yin-Yang balance and “Bianzheng Lunzhi”[辨证论治, Zhenghou(证候) differentiation and treatment], has long offered a unique lens to understand human health and disease.However, the modern scientific interpretation of TCM remains at the stage of “knowing that it works, but not knowing why it works”.展开更多
Microneedles(MNs)have attracted increasing attention as a transdermal delivery system(TDDS)[1].However,traditional volatile Chinese medicines cannot be dissolved in conventional soluble MN materials,such as hyaluronic...Microneedles(MNs)have attracted increasing attention as a transdermal delivery system(TDDS)[1].However,traditional volatile Chinese medicines cannot be dissolved in conventional soluble MN materials,such as hyaluronic acid and chitosan,making it difficult for many traditional Chinese medicine ingredients to be applied to MN.Elemene(ELE)was successfully isolated from Curcuma longa,and has numerous antitumor and curative effects[2].展开更多
Editorial Policy.Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developme...Editorial Policy.Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.展开更多
With the support of the Belt and Road Initiative(BRI),the international reach of traditional Chinese medicine(TCM)is taking shape as a“Silk Road of Health,”opening new pathways for closer connections among peoples.T...With the support of the Belt and Road Initiative(BRI),the international reach of traditional Chinese medicine(TCM)is taking shape as a“Silk Road of Health,”opening new pathways for closer connections among peoples.The journey of TCM,in turn.展开更多
The official release of the“Drug Registration Management Measures”in January 2020 marked a new milestone in the classification management of traditional Chinese medicine(TCM)registration,ushering in a new era for th...The official release of the“Drug Registration Management Measures”in January 2020 marked a new milestone in the classification management of traditional Chinese medicine(TCM)registration,ushering in a new era for the registration and application of innovative TCM drugs.This article provides a detailed analysis of the approval status of innovative TCM drugs,improved new drugs,and ancient classic prescription compound preparations from 2020 to 2024,revealing the significant achievements made in the inheritance and innovation of TCM in China.The study found that the number of New Drug Applications(NDAs)and Investigational New Drug Applications(INDs)have increased annually,with a particularly notable surge in the submission of applications for classic prescription compound preparations.The approval rates for innovative TCM drugs and improved new drugs have significantly increased,along with the streamlining of review and approval process,leading to shorter development cycles and reduced costs.Key findings include:(1)Enterprises demonstrate strong enthusiasm for the research and development of innovative and improved TCM drugs,actively engaging in various types of drug R&D and submissions;(2)Classic prescription compound preparations have become a focal point for enterprises due to their shorter development cycles and lower costs;(3)Improvement to the“three-combined”evidence system has accelerated the R&D process by incorporating real-world data.Through this study,we aim to provide valuable insights for TCM R&D enterprises and policymakers,promoting the sustained prosperity and development of the TCM sector.展开更多
基金supported by the National Natural Science Foundation of China(No.82204610)Qihang Talent Program(L2022046)+1 种基金the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(CI2021A04013)Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ15-YQ-041 and L2021029).
文摘Background:Cyperi Rhizoma,derived from Cyperus rotundus L.,is a widely used medicinal herb in traditional Chinese medicine(TCM),with Shandong Province recognized as its geo-authentic habitat.However,the quality of Cyperi Rhizoma varies significantly across different regions,potentially influencing its therapeutic efficacy.This study investigates the influence of geographic origin on the chemical composition and overall quality of Cyperi Rhizoma.Methods:A comprehensive approach,including traditional quality assessment,GC-MS(g as c hromatography-m ass s pectrometry),RP-HPLC(r everse p hase h igh-p erformance l iquid c hromatography),and FT-IR(f ourier t ransform i nfrared s pectroscopy)techniques,was employed to analyze Cyperi Rhizoma samples from Shandong Province.These methods examined the physical appearance,chemical profile,and content variations,particularly focusing onα-cyperone.Results:Traditional quality assessments revealed noticeable differences in the external characteristics of the samples.GC-MS analysis identified a variety of unique chemical constituents,while RP-HPLC and FT-IR showed significant variations inα-cyperone content,with higher levels found in Shandong samples.Conclusion:These results demonstrate that geographic origin is a critical determinant of Cyperi Rhizoma quality,with Shandong specimens exhibiting superiorα-cyperone levels and characteristic phytochemical profiles.This validates the geo-authenticity concept in TCM and provides actionable data for developing evidence-based quality standards,suggesting that provenance should be prioritized in medicinal material selection and pharmacopeial specifications.
基金supported by the National Natural Science Foundation of China(82574477)the Jiangsu Provincial Traditional Chinese Medicine Science and Technology Development Plan(QN202426)+5 种基金Jiangsu Province“333 High-level Talents Training Project”((2024)3-0189)Youth Talent Support Project of the Jiangsu Association for Science and Technology(TJ-2023-053)Shanxi Provincial Department-Municipal Key Laboratory Cultivation Base for Quality Enhancement and Utilization of Shangdang Chinese Medicinal Materials(KF202401)Fundamental Research Program of Shanxi Province(202403021221211)the research project supported by the Shanxi Scholarship Council of China(No.2023-158)Open Project of Key Laboratory of Tibetan Medicine Basic Research,Ministry of Education.
文摘The global prevalence of metabolic-associated fatty liver disease(MAFLD)is on the rise,seriously threatening human health.Currently,no specific approved drugs are available for its treatment.This paper reviews the pathogenesis of MAFLD,covering aspects like lipid accumulation and insulin resistance,oxidative stress,endoplasmic reticulum stress(ERS),lipotoxicity-induced hepatocyte damage,and fibrosis.It also elaborates on multiple treatment approaches for MAFLD,including metabolic regulation,improvement of the gut-liver axis interaction,modulation of immune and inflammatory pathways,enhancement of the adipose tissue-liver interaction,alleviation of fibrosis,prevention of hepatocyte injury,and traditional Chinese medicine(TCM)external therapies.Additionally,natural product research advancements,individual Chinese medicine components,and mixed herbal formulas for MAFLD treatment is provided.Many natural products and traditional Chinese medicines exhibit favorable effects in regulating lipid metabolism,anti-inflammation,and anti-oxidation,offering new directions and potential drug options for MAFLD treatment.This is expected to provide a reference for future clinical treatment and drug development.
基金supported by Healthy China initiative of Traditional Chinese Medicine(No.889042).
文摘Currently,the number of patients with myopia is increasing rapidly across the globe.Traditional Chinese medicine(TCM),with its long history and rich experience,has shown promise in effectively managing and treating this condition.Nevertheless,considering the vast amount of research that is currently being conducted,focusing on the utilization of TCM in the management of myopia,there is an urgent requirement for a thorough and comprehensive review.The review would serve to clarify the practical applications of TCM within this specific field,and it would also aim to elucidate the underlying mechanisms that are at play,providing a deeper understanding of how TCM principles can be effectively integrated into modern medical practices.Here,some modern medical pathogenesis of myopia and appropriate TCM techniques studies are summarized in the prevention and treatment of myopia.Further,we discussed the potential mechanisms and the future research directions of TCM against myopia.Identifying these mechanisms is crucial for understanding how TCM can be effectively utilized in this context.The combination of various TCM methods or the combination of traditional Chinese and Western medicine is of great significance for the prevention and control of myopia in the future.
基金supported by the Innovative Team Project of Ordinary Universities in Guangdong Province(No.2022KCXTD016).
文摘Chemotherapy-induced diarrhea(CID)is a major concern for cancer patients and is associated with significant morbidity and mortality.Currently,the clinical management of CID is limited.The utilization of antidiarrheal medications,such as loperamide and octreotide,is relatively limited because of their unsatisfactory efficacy and adverse effects.In recent years,traditional Chinese medicine(TCM)has attracted great interest because of its beneficial effect in treating CID,which has multitarget and low-toxicity therapeutic characteristics.TCM exhibits remarkable therapeutic potential in the prevention and treatment of CID.It can alleviate and treat CID by regulating chemical drug metabolism,improving the integrity of the intestinal barrier,stimulating proliferation while suppressing the apoptosis of intestinal epithelial cells,ameliorating oxidative stress and inflammation and regulating bile acids and aquaporins.However,large-scale,randomized,double-blind clinical trials of TCM for the treatment of CID are lacking,and most preclinical experiments have not been translated to clinical trials.Accordingly,this review highlights the clinical efficacy and molecular mechanisms of TCM against CID via PubMed,Web of Science and China National Knowledge Infrastructure and proposes that future research on TCM against CID should focus on strengthening the connection from bench to bed,which may help to comprehensively evaluate the therapeutic potential of TCM against CID.
文摘Traditional Medicine(TM),particularly Traditional Chinese Medicine(TCM),is an indispensable component of the global healthcare system,offering unique insights to modern medical science.Clinical efficacy is the bedrock for the inheritance and development of TM.To meet the growing demand for high-quality healthcare,it is imperative to integrate TM with modern technology to address the issue of insufficient evidence for the efficacy of TM.
文摘Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.
文摘Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.
文摘Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.
基金supported by Young Talent Program of The Affiliated Hospital of Xuzhou Medical University,Advanced Program of The Affiliated Hospital of Xuzhou Medical University(PYJH2024210)Medical Research Project of Jiangsu Provincial Health Commission(H2023050)National Natural Science Foundation of China(No.32301278).
文摘Traditional Chinese medicines(TCMs)have been used for centuries to treat and manage various diseases.However,their effective delivery to targeted sites may be a major challenge due to their poor water solubility,low bio-availability,and potential toxicity.Nanocarriers,such as liposomes,polymeric nanoparticles,inorganic nanoparticles,and organic/inorganic nanohybrids based on active constituents from TCMs have been extensively studied as a promising strategy to improve the delivery of active constituents from TCMs to achieve a higher therapeutic effect with fewer side effects compared to conventional formulations.This article summarizes the recent progress in nanocarrier-based delivery systems.Nanotechnology can broaden the scope of applications of traditional Chinese medicine.The concept of nano-traditional Chinese medicine(nano-TCM)is introduced,and the progress of nanomedicine,the advantages,and the development direction of nano-TCM are reviewed,providing new ideas for the development of nano-TCM.
文摘Objective:To analyze the application value of prescription management of traditional Chinese medicine formula granules in reducing unreasonable prescriptions.Methods:From January to June 2024,before improving prescription management strategies,118 patients treated with traditional Chinese medicine formula granules were included in the control group.From July to December 2024,after improving prescription management strategies,118 patients treated with traditional Chinese medicine formula granules were included in the observation group.The unqualified prescription rate,incidence of adverse reactions,complaint rate,and satisfaction were compared.Results:The unqualified prescription rate of traditional Chinese medicine formula granules in the observation group was lower than that in the control group(P<0.05);the incidence of adverse reactions and patient complaint rate of traditional Chinese medicine formula granules in the observation group were lower than those in the control group(P<0.05);the satisfaction of traditional Chinese medicine formula granules in the observation group was higher than that in the control group(P<0.05).Conclusion:Improving the prescription management strategy of traditional Chinese medicine formula granules can reduce the unqualified prescription rate and the incidence of adverse drug reactions,reduce patient complaints,and is conducive to improving patient satisfaction.
文摘In the dynamic landscape of modern healthcare and precision medicine,the digital revolution is reshaping medical industries at an unprecedented pace,and traditional Chinese medicine(TCM)is no exception[1-4].The paper“From digits towards digitization:the past,present,and future of traditional Chinese medicine”by Academician&TCM National Master Qi WANG(王琦).
基金Science and Technology strategic cooperation Programs of Luzhou Municipal People’s Government and Southwest Medical University (2019LZXNYD-P01DUAN)National Key R&D Program of China (2024YFC3505400)Regional Key R&D Program of Ningxia Hui Autonomous Region (2024BEG01003)。
文摘Modern western medicine typically focuses on treating specific symptoms or diseases,and traditional Chinese medicine(TCM)emphasizes the interconnections of the body’s various systems under external environment and takes a holistic approach to preventing and treating diseases.Phenomics was initially introduced to the field of TCM in 2008 as a new discipline that studies the laws of integrated and dynamic changes of human clinical phenomes under the scope of the theories and practices of TCM based on phenomics.While TCM Phenomics 1.0 has initially established a clinical phenomic system centered on Zhenghou(a TCM definition of clinical phenome),bottlenecks remain in data standardization,mechanistic interpretation,and precision intervention.Here,we systematically elaborates on the theoretical foundations,technical pathways,and future challenges of integrating digital medicine with TCM phenomics under the framework of“TCM phenomics 2.0”,which is supported by digital medicine technologies such as artificial intelligence,wearable devices,medical digital twins,and multi-omics integration.This framework aims to construct a closed-loop system of“Zhenghou–Phenome–Mechanism–Intervention”and to enable the digitization,standardization,and precision of disease diagnosis and treatment.The integration of digital medicine and TCM phenomics not only promotes the modernization and scientific transformation of TCM theory and practice but also offers new paradigms for precision medicine.In practice,digital tools facilitate multi-source clinical data acquisition and standardization,while AI and big data algorithms help reveal the correlations between clinical Zhenghou phenomes and molecular mechanisms,thereby improving scientific rigor in diagnosis,efficacy evaluation,and personalized intervention.Nevertheless,challenges persist,including data quality and standardization issues,shortage of interdisciplinary talents,and insufficiency of ethical and legal regulations.Future development requires establishing national data-sharing platforms,strengthening international collaboration,fostering interdisciplinary professionals,and improving ethical and legal frameworks.Ultimately,this approach seeks to build a new disease identification and classification system centered on phenomes and to achieve the inheritance,innovation,and modernization of TCM diagnostic and therapeutic patterns.
基金funded by the National Natural Science Foundation of China(Grant Nos.:82222068,82070423,82270348,and 82173779)the Innovation Team and Talents Cultivation Pro-gram of National Administration of Traditional Chinese Medicine,China(Grant No:ZYYCXTD-D-202206)+1 种基金Fujian Province Science and Technology Project,China(Grant Nos.:2021J01420479,2021J02058,2022J011374,and 2022J02057)Fundamental Research Funds for the Chinese Central Universities,China(Grant No.:20720230070).
文摘Insect-derived traditional Chinese medicine(TCM)constitutes an essential component of TCM,with the earliest records found in“52 Bingfang”(Prescriptions of fifty-two diseases,which is one of the earliest Chinese medical prescriptions).
基金2020 Yunnan Province International Commissioner(Individual)Recognition Work Project(202003AK140041)2024 Yunnan Provincial Philosophy and Social Science Innovation Team:Research on the Exchange and Integration of Traditional Medicine in Yunnan(2024CX09)2023 Hospital-level Project of School of Basic Medical Sciences,Yunnan University of Traditional Chinese Medicine,“Comparison and Research on Traditional Medicine Treatment Methods in China and Burma”(2023CBMS009).
文摘Traditional medicine in Myanmar has a long history,combining the local natural environment,culture,and religious beliefs to form a unique medical system.This article adopts the method of literature research,focusing on the existing book“Milestones of Traditional Medicine in Myanmar”,and reviewing existing literature to analyze historical and contemporary sources.Elaborate on the question of how the history of traditional medicine in Myanmar originated and has continued to develop until now.These histories have proven that traditional medicine in Myanmar,despite facing numerous obstacles,has always been used by the people of Myanmar and has unique value,which deserves our continued attention and inheritance.
文摘This review highlights the therapeutic qualities of crustaceans such as crabs,shrimps,lobsters,and similar species that have historically been utilized for promoting human health.This study is particularly valuable as our reliance on synthetic medications and chemicals for maintaining good health increases,often leading to numerous side effects.Thus,there is a pressing need to explore alternative and natural solutions that can enhance general well-being and avert illnesses.Crustaceans were found to have numerous compounds that possess qualities such as fighting microbial pathogens(antimicrobial),diminishing inflammation(anti-inflammatory),exhibiting antioxidant properties,and regulating the immune system(immuno-modulatory),making them helpful in addressing various health issues.This review highlights 25 species of crustaceans for having multiple exceptional benefits to human health.A crucial aspect of this study relied on ancient Vedic medical manuscripts,from which data was gathered regarding the types of crustaceans and their applications for preserving health.We collected data that was determined to uphold these conventional theories.The key findings of the study also include the versatile applications of multiple compounds that can be extracted from crustacean byproducts like their shell wastes.The major compounds are Chitin and Chitosan being greatly utilized in fields like agriculture,cosmetology,in medical sciences for tissue regeneration and drug delivery,paper and textile industry.Compounds like Astaxanthin were observed with positive cardiovascular effect and antioxidant properties while Glucosamine,Chondroitin and Taurine were found to be essential components of bio-metabolic pathways and various bio-synthesizing processes inside human body.Therefore,the research highlights the important contribution of crustaceans in multiple sectors and also points out their economic value.This systematic literature review seeks to serve as a resource for researchers,healthcare providers,and pharmaceutical professionals who utilize insights regarding crustaceans and their beneficial byproducts for sustainable applications in their respective areas.
文摘Traditional Chinese medicine (TCM) with its millenniaold wisdom rooted in the principles of holistic Yin-Yang balance and “Bianzheng Lunzhi”[辨证论治, Zhenghou(证候) differentiation and treatment], has long offered a unique lens to understand human health and disease.However, the modern scientific interpretation of TCM remains at the stage of “knowing that it works, but not knowing why it works”.
基金supported by Shandong Provincial Natural Science Foundation Innovation and Development Joint Project,China(Grant No.:ZR2021LZY039)Zhejiang Provincial Traditional Chinese Medicine Science and Technology Plan,China(Grant No.:2021ZB184)。
文摘Microneedles(MNs)have attracted increasing attention as a transdermal delivery system(TDDS)[1].However,traditional volatile Chinese medicines cannot be dissolved in conventional soluble MN materials,such as hyaluronic acid and chitosan,making it difficult for many traditional Chinese medicine ingredients to be applied to MN.Elemene(ELE)was successfully isolated from Curcuma longa,and has numerous antitumor and curative effects[2].
文摘Editorial Policy.Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.
文摘With the support of the Belt and Road Initiative(BRI),the international reach of traditional Chinese medicine(TCM)is taking shape as a“Silk Road of Health,”opening new pathways for closer connections among peoples.The journey of TCM,in turn.
文摘The official release of the“Drug Registration Management Measures”in January 2020 marked a new milestone in the classification management of traditional Chinese medicine(TCM)registration,ushering in a new era for the registration and application of innovative TCM drugs.This article provides a detailed analysis of the approval status of innovative TCM drugs,improved new drugs,and ancient classic prescription compound preparations from 2020 to 2024,revealing the significant achievements made in the inheritance and innovation of TCM in China.The study found that the number of New Drug Applications(NDAs)and Investigational New Drug Applications(INDs)have increased annually,with a particularly notable surge in the submission of applications for classic prescription compound preparations.The approval rates for innovative TCM drugs and improved new drugs have significantly increased,along with the streamlining of review and approval process,leading to shorter development cycles and reduced costs.Key findings include:(1)Enterprises demonstrate strong enthusiasm for the research and development of innovative and improved TCM drugs,actively engaging in various types of drug R&D and submissions;(2)Classic prescription compound preparations have become a focal point for enterprises due to their shorter development cycles and lower costs;(3)Improvement to the“three-combined”evidence system has accelerated the R&D process by incorporating real-world data.Through this study,we aim to provide valuable insights for TCM R&D enterprises and policymakers,promoting the sustained prosperity and development of the TCM sector.
