Infrastructure development within protected areas has become a critical concern in biodiversity conservation,particularly in ecologically sensitive regions like Bantimurung Bulusaraung National Park (TN Babul), Indone...Infrastructure development within protected areas has become a critical concern in biodiversity conservation,particularly in ecologically sensitive regions like Bantimurung Bulusaraung National Park (TN Babul), Indonesia. Thisstudy aims to evaluate the ecological, social, economic, institutional, and infrastructural sustainability of the Maros–Watampone road corridor that crosses TN Babul. Using a qualitative descriptive design, the research employed theMultidimensional Scaling (MDS) method supported by leverage and Monte Carlo analysis. Data were gathered fromkey stakeholders through purposive sampling and analyzed based on sustainability attributes across five dimensions.The findings reveal that environmental, institutional, and infrastructure dimensions scored in the "less sustainable"category, indicating high ecological risk and governance gaps. In contrast, economic and social dimensions weremoderately sustainable, reflecting emerging opportunities for inclusive growth. Sensitive attributes influencingsustainability include habitat fragmentation, road design, governance coordination, and community participation. Thestudy concludes that balancing development with conservation requires integrated, multi-stakeholder strategies andtargeted interventions that address the most vulnerable sustainability dimensions.展开更多
本文于2025年07月发表于《Blood》杂志,发表后引起业内广泛关注,Blood发布述评文章(Thrombopoiesis comes full circle,Amelia A Rodolf,Owen J T McCarty,2025,10,23)。本文题录为:Wu H,Lu Y,Sun D,et al.circFUT8promotes proplatelet...本文于2025年07月发表于《Blood》杂志,发表后引起业内广泛关注,Blood发布述评文章(Thrombopoiesis comes full circle,Amelia A Rodolf,Owen J T McCarty,2025,10,23)。本文题录为:Wu H,Lu Y,Sun D,et al.circFUT8promotes proplatelet formation by interacting with IGF2BP2 and stabilizing TNS1 mRNA in megakaryocytes.Blood.2025;146(17):2119-2132.该研究首次揭示了环状RNA circFUT8促进血小板生成的重要作用,阐明了circFUT8通过与IGF2BP2相互作用促进巨核细胞中TNS1 mRNA的稳定,进而调控巨核细胞肌动蛋白骨架重排的作用机制。本研究揭示了血小板生成调控的新机制,拓宽了环形RNA的生物学功能,为血小板减少症提供了潜在的治疗靶点,也为血小板体外生成策略提供了新的理论依据。现在作者将再次通过佳文解读的方式来阐述这一研究。展开更多
文摘Infrastructure development within protected areas has become a critical concern in biodiversity conservation,particularly in ecologically sensitive regions like Bantimurung Bulusaraung National Park (TN Babul), Indonesia. Thisstudy aims to evaluate the ecological, social, economic, institutional, and infrastructural sustainability of the Maros–Watampone road corridor that crosses TN Babul. Using a qualitative descriptive design, the research employed theMultidimensional Scaling (MDS) method supported by leverage and Monte Carlo analysis. Data were gathered fromkey stakeholders through purposive sampling and analyzed based on sustainability attributes across five dimensions.The findings reveal that environmental, institutional, and infrastructure dimensions scored in the "less sustainable"category, indicating high ecological risk and governance gaps. In contrast, economic and social dimensions weremoderately sustainable, reflecting emerging opportunities for inclusive growth. Sensitive attributes influencingsustainability include habitat fragmentation, road design, governance coordination, and community participation. Thestudy concludes that balancing development with conservation requires integrated, multi-stakeholder strategies andtargeted interventions that address the most vulnerable sustainability dimensions.
文摘本文于2025年07月发表于《Blood》杂志,发表后引起业内广泛关注,Blood发布述评文章(Thrombopoiesis comes full circle,Amelia A Rodolf,Owen J T McCarty,2025,10,23)。本文题录为:Wu H,Lu Y,Sun D,et al.circFUT8promotes proplatelet formation by interacting with IGF2BP2 and stabilizing TNS1 mRNA in megakaryocytes.Blood.2025;146(17):2119-2132.该研究首次揭示了环状RNA circFUT8促进血小板生成的重要作用,阐明了circFUT8通过与IGF2BP2相互作用促进巨核细胞中TNS1 mRNA的稳定,进而调控巨核细胞肌动蛋白骨架重排的作用机制。本研究揭示了血小板生成调控的新机制,拓宽了环形RNA的生物学功能,为血小板减少症提供了潜在的治疗靶点,也为血小板体外生成策略提供了新的理论依据。现在作者将再次通过佳文解读的方式来阐述这一研究。
