目的探讨超声心动图检测Tei指数对孕中晚期子痫前期孕妇胎儿心脏功能及出生情况的影响。方法选取2022年1月—2023年10月江西省妇幼保健院收治的重度子痫前期孕妇40例作为A组,轻度子痫前期孕妇50例作为B组,选取2022年1月—2023年10月同...目的探讨超声心动图检测Tei指数对孕中晚期子痫前期孕妇胎儿心脏功能及出生情况的影响。方法选取2022年1月—2023年10月江西省妇幼保健院收治的重度子痫前期孕妇40例作为A组,轻度子痫前期孕妇50例作为B组,选取2022年1月—2023年10月同期正常孕妇35例作为C组。所有孕妇均予以超声心动图检查,比较3组孕妇新生儿心室Tei指数、心室功能指标及出生情况,采用Pearson相关性分析孕中晚期子痫前期孕妇胎儿心室Tei指数与胎儿出生情况的关系。结果与C组比较(0.25±0.02,0.28±0.02),A组和B组左室Tei指数(0.47±0.03,0.34±0.01)以及右室Tei指数(0.53±0.02,0.37±0.03)均显著上升(P<0.05),与B组比较(0.34±0.01,0.37±0.03),A组左室Tei指数(0.47±0.03)和右室Tei指数(0.53±0.02)均显著上升(P<0.05)。3组左室Tei指数和右室Tei指数比较差异有统计学意义(P<0.05)。与C组比较(64.01±8.94 ms,169.02±7.72 ms,67.44±9.76 ms,172.33±7.30 ms),A组左心室等容时间(71.25±9.80)ms及右心室等容时间(78.25±11.89)ms显著上升,左心室射血时间(162.21±5.36)ms及右心室射血时间(165.24±6.58)ms显著下降;B组右心室等容时间(74.20±10.34)ms显著上升,右心室射血时间(167.83±8.33)ms显著下降(P<0.05)。与B组比较(165.65±6.87)ms,A组左心室射血时间(162.21±5.36)ms显著下降(P<0.05)。3组心室功能指标比较差异有统计学意义(P<0.05)。与C组比较(9.21±0.05分,9.99±0.06分),A组与B组孕妇新生儿出生孕周1min Apgar评分(8.47±1.25分,9.05±0.08分)及5 min Apgar评分(9.83±0.33分,9.95±0.29分)均显著下降(P<0.05),此外,A组孕妇新生儿出生体重(2230.28±536.96)g也显著下降(P<0.05)。与B组比较(3125.37±398.54 g,37.61±1.04周,9.05±0.08分),A组新生儿出生体重(2230.28±536.96)g、出生孕周(34.53±2.14)周、1 min Apgar评分(8.47±1.25)分显著下降(P<0.05)。3组孕妇新生儿出生情况比较差异有统计学意义(P<0.05)。孕中晚期子痫前期孕妇胎儿右心室Tei指数与出生体重、出生孕周、1 min Apgar评分及5 min Apgar评分呈负相关(r=-0.528,-0.385,-0.763,-0.572,均P<0.05)。结论孕中晚期子痫前期胎儿Tei指数与孕妇疾病程度相关,且以右心室出现损伤为主,此外Tei指数与胎儿出生时Apgar评分、孕周及体重相关,有望成为预测胎儿出生情况的一个指标。展开更多
Lead-free halide perovskites provide a promising solution for efficient thermoelectric materials due to their ultralow lattice thermal conductivity(κ_(L)).However,disadvantages such as the electrically resistive natu...Lead-free halide perovskites provide a promising solution for efficient thermoelectric materials due to their ultralow lattice thermal conductivity(κ_(L)).However,disadvantages such as the electrically resistive nature strongly affect their power factor.In this work,we introduced the Te-based halide perovskites thermoelectric material Cs_(2)TeI_(6),which is already known as a promising candidate for photovoltaic applications due to its moderate band gap.Our findings reveal that Cs_(2)TeI_(6)has an exceptionally ultralow κ_(L)at room temperature,reaching as low as 0.17 W·m^(-1)·K^(-1).We found that the four-phonon scattering processes play a dominant role in suppressing the thermal transport,leading to an approximate 50% reduction in its particle-like thermal conductivity κ_(p) at 300 K.The ultralow κ_(L)can be mainly attributed to the strong discrepancy in bonding strength,which induces large anharmonicity.The flat and dense phonon dispersions result in a strong phonon scattering rate,making it easy to generate wavelike phonon tunneling.After accounting for the wavelike thermal conductivity κ_(c),a nonstandard T^(-0.30)temperature dependence was observed.Benefiting from the ultralow κ_(L),n-type Cs_(2)TeI_(6)is predicted to achieve an extraordinary ZT of 2.26 at 700 K.This work highlights a pathway for searching high-performance and low-cost thermoelectrics based on lead-free halide perovskites.展开更多
目的探讨妊娠期糖尿病(GDM)孕妇胎儿心脏功能的变化及超声心动图Tei指数对胎儿心脏功能的评价作用。方法选取GDM孕妇108例,根据血糖控制情况分为血糖控制理想56例(GDM1组)和血糖控制不良52例(GDM2组);选取年龄、孕周及BMI相匹配的正常...目的探讨妊娠期糖尿病(GDM)孕妇胎儿心脏功能的变化及超声心动图Tei指数对胎儿心脏功能的评价作用。方法选取GDM孕妇108例,根据血糖控制情况分为血糖控制理想56例(GDM1组)和血糖控制不良52例(GDM2组);选取年龄、孕周及BMI相匹配的正常妊娠孕妇50例作为对照组。测量三组空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(GHb A_(1c))。应用多普勒超声心动图测定三组胎儿心脏结构、功能指标及左、右心室的Tei指数。结果 GDM2组FPG、2 h PG及GHb A_(1c)均高于GDM1组和对照组(P均<0.05)。GDM2组胎儿左室壁厚度、右室壁厚度、右室舒张末期内径(RVDd)、左室短轴缩短率(LVFS)、右室短轴缩短率及左室射血分数(LVEF)均高于对照组(P均<0.05),GDM2组的RVDd、右室收缩末期内径、LVFS及LVEF均高于GDM1组(P均<0.05),GDM1组LVFS高于对照组(P<0.05)。GDM1及GDM2组胎儿左、右心室Tei指数均高于对照组(P均<0.05),GDM2组胎儿左、右心室Tei指数高于GDM1组和对照组(P均<0.05)。结论 Tei指数与GDM孕妇胎儿心脏功能变化相关,可作为临床综合评估GDM胎儿心肌受累的一项简单可靠指标。展开更多
文摘目的比较加温湿化高流量鼻导管通气(heated humidified high-flow nasal cannula,HHHFNC)和经鼻持续气道正压通气(nasal continuous positive airway pressure,NCPAP)在早产儿呼吸窘迫综合征(neonatal respiratory distress syndrome,NRDS)初始治疗的疗效及对心功能的影响。方法选自徐州市中心医院2021年1月~2023年11月收治的胎龄<35周、需无创通气的早产儿NRDS进行前瞻性研究,随机分为HHHFNC组和NCPAP组,初始治疗分别采用HHHFNC和NCPAP。比较疗效、安全性及对心功能的影响。结果HHHFNC组55例,NCPAP组53例。两组给予肺表面活性剂的例数和总剂量、入组24h内呼吸暂停次数、无创通气时长、无创通气失败例数、达全肠道喂养时间、住院时长和住院费用等比较,差异均无统计学意义(P>0.05)。HHHFNC组鼻损伤率明显低于NCPAP组(0 vs 11.3%,P=0.032);两组气胸、Ⅱ~Ⅲ期坏死性小肠结肠炎、血流动力学显著异常动脉导管未闭、Ⅱ~Ⅳ级脑室内出血、支气管肺发育不良和首次筛查需要治疗的早产儿视网膜病等比较,差异均无统计学意义(P>0.05)。两组无创通气24±6h和48±6h、组间吸入氧浓度和动脉血二氧化碳分压比较,差异无统计学意义(P>0.05),组间血浆B型尿钠肽(183.9±48.5ng/L vs 187.8±51.4ng/L,189.4±50.9ng/L vs 180.2±45.1ng/L)和右室Tei指数(0.38±0.05 vs 0.40±0.06,0.38±0.06 vs 0.39±0.06)比较,差异无统计学意义(P>0.05)。结论在胎龄<35周、需要无创通气的NRDS早产儿初始治疗中,HHHFNC疗效与NCPAP相似,鼻损伤率更低。两者其他安全性指标及对心功能的影响相似。
文摘目的探讨超声心动图检测Tei指数对孕中晚期子痫前期孕妇胎儿心脏功能及出生情况的影响。方法选取2022年1月—2023年10月江西省妇幼保健院收治的重度子痫前期孕妇40例作为A组,轻度子痫前期孕妇50例作为B组,选取2022年1月—2023年10月同期正常孕妇35例作为C组。所有孕妇均予以超声心动图检查,比较3组孕妇新生儿心室Tei指数、心室功能指标及出生情况,采用Pearson相关性分析孕中晚期子痫前期孕妇胎儿心室Tei指数与胎儿出生情况的关系。结果与C组比较(0.25±0.02,0.28±0.02),A组和B组左室Tei指数(0.47±0.03,0.34±0.01)以及右室Tei指数(0.53±0.02,0.37±0.03)均显著上升(P<0.05),与B组比较(0.34±0.01,0.37±0.03),A组左室Tei指数(0.47±0.03)和右室Tei指数(0.53±0.02)均显著上升(P<0.05)。3组左室Tei指数和右室Tei指数比较差异有统计学意义(P<0.05)。与C组比较(64.01±8.94 ms,169.02±7.72 ms,67.44±9.76 ms,172.33±7.30 ms),A组左心室等容时间(71.25±9.80)ms及右心室等容时间(78.25±11.89)ms显著上升,左心室射血时间(162.21±5.36)ms及右心室射血时间(165.24±6.58)ms显著下降;B组右心室等容时间(74.20±10.34)ms显著上升,右心室射血时间(167.83±8.33)ms显著下降(P<0.05)。与B组比较(165.65±6.87)ms,A组左心室射血时间(162.21±5.36)ms显著下降(P<0.05)。3组心室功能指标比较差异有统计学意义(P<0.05)。与C组比较(9.21±0.05分,9.99±0.06分),A组与B组孕妇新生儿出生孕周1min Apgar评分(8.47±1.25分,9.05±0.08分)及5 min Apgar评分(9.83±0.33分,9.95±0.29分)均显著下降(P<0.05),此外,A组孕妇新生儿出生体重(2230.28±536.96)g也显著下降(P<0.05)。与B组比较(3125.37±398.54 g,37.61±1.04周,9.05±0.08分),A组新生儿出生体重(2230.28±536.96)g、出生孕周(34.53±2.14)周、1 min Apgar评分(8.47±1.25)分显著下降(P<0.05)。3组孕妇新生儿出生情况比较差异有统计学意义(P<0.05)。孕中晚期子痫前期孕妇胎儿右心室Tei指数与出生体重、出生孕周、1 min Apgar评分及5 min Apgar评分呈负相关(r=-0.528,-0.385,-0.763,-0.572,均P<0.05)。结论孕中晚期子痫前期胎儿Tei指数与孕妇疾病程度相关,且以右心室出现损伤为主,此外Tei指数与胎儿出生时Apgar评分、孕周及体重相关,有望成为预测胎儿出生情况的一个指标。
基金supported by the National Natural Science Foundation of China(Grant Nos.12204482 and U2330104)the Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi(Grant No.2020L0537)+2 种基金the Natural Science Foundation of Shanxi Province(Grant No.202403021221164)Higher Education Teaching Reform and Innovation Project of Shanxi Province(Grant No.J20220480)Graduate Curriculum Ideological and Political Education Project of Shanxi Normal University(Grant No.010520233013)。
文摘Lead-free halide perovskites provide a promising solution for efficient thermoelectric materials due to their ultralow lattice thermal conductivity(κ_(L)).However,disadvantages such as the electrically resistive nature strongly affect their power factor.In this work,we introduced the Te-based halide perovskites thermoelectric material Cs_(2)TeI_(6),which is already known as a promising candidate for photovoltaic applications due to its moderate band gap.Our findings reveal that Cs_(2)TeI_(6)has an exceptionally ultralow κ_(L)at room temperature,reaching as low as 0.17 W·m^(-1)·K^(-1).We found that the four-phonon scattering processes play a dominant role in suppressing the thermal transport,leading to an approximate 50% reduction in its particle-like thermal conductivity κ_(p) at 300 K.The ultralow κ_(L)can be mainly attributed to the strong discrepancy in bonding strength,which induces large anharmonicity.The flat and dense phonon dispersions result in a strong phonon scattering rate,making it easy to generate wavelike phonon tunneling.After accounting for the wavelike thermal conductivity κ_(c),a nonstandard T^(-0.30)temperature dependence was observed.Benefiting from the ultralow κ_(L),n-type Cs_(2)TeI_(6)is predicted to achieve an extraordinary ZT of 2.26 at 700 K.This work highlights a pathway for searching high-performance and low-cost thermoelectrics based on lead-free halide perovskites.
文摘目的探讨妊娠期糖尿病(GDM)孕妇胎儿心脏功能的变化及超声心动图Tei指数对胎儿心脏功能的评价作用。方法选取GDM孕妇108例,根据血糖控制情况分为血糖控制理想56例(GDM1组)和血糖控制不良52例(GDM2组);选取年龄、孕周及BMI相匹配的正常妊娠孕妇50例作为对照组。测量三组空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(GHb A_(1c))。应用多普勒超声心动图测定三组胎儿心脏结构、功能指标及左、右心室的Tei指数。结果 GDM2组FPG、2 h PG及GHb A_(1c)均高于GDM1组和对照组(P均<0.05)。GDM2组胎儿左室壁厚度、右室壁厚度、右室舒张末期内径(RVDd)、左室短轴缩短率(LVFS)、右室短轴缩短率及左室射血分数(LVEF)均高于对照组(P均<0.05),GDM2组的RVDd、右室收缩末期内径、LVFS及LVEF均高于GDM1组(P均<0.05),GDM1组LVFS高于对照组(P<0.05)。GDM1及GDM2组胎儿左、右心室Tei指数均高于对照组(P均<0.05),GDM2组胎儿左、右心室Tei指数高于GDM1组和对照组(P均<0.05)。结论 Tei指数与GDM孕妇胎儿心脏功能变化相关,可作为临床综合评估GDM胎儿心肌受累的一项简单可靠指标。
