Geomechanical properties of rocks vary across different measurement scales,primarily due to heterogeneity.Micro-scale geomechanical tests,including micro-scale“scratch tests”and nano-scale nanoindentation tests,are ...Geomechanical properties of rocks vary across different measurement scales,primarily due to heterogeneity.Micro-scale geomechanical tests,including micro-scale“scratch tests”and nano-scale nanoindentation tests,are attractive at different scales.Each method requires minimal sample volume,is low cost,and includes a relatively rapid measurement turnaround time.However,recent micro-scale test results–including scratch test results and nanoindentation results–exhibit tangible variance and uncertainty,suggesting a need to correlate mineral composition mapping to elastic modulus mapping to isolate the relative impact of specific minerals.Different research labs often utilize different interpretation methods,and it is clear that future micro-mechanical tests may benefit from standardized testing and interpretation procedures.The objectives of this study are to seek options for standardized testing and interpretation procedures,through two specific objectives:(1)Quantify chemical and physical controls on micro-mechanical properties and(2)Quantify the source of uncertainties associated with nanoindentation measurements.To reach these goals,we conducted mechanical tests on three different scales:triaxial compression tests,scratch tests,and nanoindentation tests.We found that mineral phase weight percentage is highly correlated with nanoindentation elastic modulus distribution.Finally,we conclude that nanoindentation testing is a mineralogy and microstructure-based method and generally yields significant uncertainty and overestimation.The uncertainty of the testing method is largely associated with not mapping pore space a priori.Lastly,the uncertainty can be reduced by combining phase mapping and modulus mapping with substantial and random data sampling.展开更多
This study presents the results of a Monte Carlo simulation to compare the statistical power of Siegel-Tukey and Savage tests.The main purpose of the study is to evaluate the statistical power of both tests in scenari...This study presents the results of a Monte Carlo simulation to compare the statistical power of Siegel-Tukey and Savage tests.The main purpose of the study is to evaluate the statistical power of both tests in scenarios involving Normal,Platykurtic and Skewed distributions over different sample sizes and standard deviation values.In the study,standard deviation ratios were set as 2,3,4,1/2,1/3 and 1/4 and power comparisons were made between small and large sample sizes.For equal sample sizes,small sample sizes of 5,8,10,12,16 and 20 and large sample sizes of 25,50,75 and 100 were used.For different sample sizes,the combinations of(4,16),(8,16),(10,20),(16,4),(16,8)and(20,10)small sample sizes and(10,30),(30,10),(50,75),(50,100),(75,50),(75,100),(100,50)and(100,75)large sample sizes were examined in detail.According to the findings,the power analysis under variance heterogeneity conditions shows that the Siegel-Tukey test has a higher statistical power than the other nonparametric Savage test at small and large sample sizes.In particular,the Siegel-Tukey test was reported to offer higher precision and power under variance heterogeneity,regardless of having equal or different sample sizes.展开更多
In recent years,the application scenarios of electrical and electronic products have become increasingly diverse worldwide.The impact of climatic environmental tests on the performance of related products has attracte...In recent years,the application scenarios of electrical and electronic products have become increasingly diverse worldwide.The impact of climatic environmental tests on the performance of related products has attracted much attention,and formulating scientific and reasonable environmental test plans has become an important step to ensure product quality and reliability.展开更多
BACKGROUND Small intestinal bacterial overgrowth(SIBO)is suspected and excluded frequently in functional gastrointestinal(GI)disorders.Children presenting with various esophago-gastro-duodenal(upper GI)symptoms are ra...BACKGROUND Small intestinal bacterial overgrowth(SIBO)is suspected and excluded frequently in functional gastrointestinal(GI)disorders.Children presenting with various esophago-gastro-duodenal(upper GI)symptoms are rarely subjected to investig-ations for SIBO.AIM To estimate the frequency of SIBO in children having functional upper GI sym-ptoms(as cases)and to compare the result of the SIBO status to that of the con-trols.METHODS Children aged 6 to 18 who presented with upper GI symptoms were selected for the study.All children were subjected to upper GI endoscopy before being advised of any proton pump inhibitors(PPIs).Children with normal endoscopy were assigned as cases,and children having any endoscopic lesion were design-ated as controls.Both groups were subjected to a glucose-hydrogen breath test by Bedfont Gastrolyser.RESULTS A total of 129 consecutive children who were naive to PPIs and had normal ba-seline investigations were included in the study.Among them,67 patients had endoscopic lesions and served as the control group,with six cases being excluded due to the presence of Helicobacter pylori in gastric biopsies.Sixty-two children with normal endoscopy results formed the case group.In the case group,35 children(59%)tested positive for hydrogen breath tests,compared to 13 children(21%)in the control group.The calculated odds ratio was 5.38(95%confidence interval:2.41-12.0),which was statistically significant.Further analysis of symptoms revealed that nausea,halitosis,foul-smelling eructation,and epigastric fullness were positive predictors of SIBO.CONCLUSION It is worthwhile to investigate and treat SIBO in all children presenting with upper GI symptoms that are not explained by endoscopy findings.展开更多
The China Spallation Neutron Source(CSNS)is the fourth pulsed accelerator-driven neutron source in the world,and it achieved its design target of 100 kW in 2020.The planned China Spallation Neutron Source Phase II(CSN...The China Spallation Neutron Source(CSNS)is the fourth pulsed accelerator-driven neutron source in the world,and it achieved its design target of 100 kW in 2020.The planned China Spallation Neutron Source Phase II(CSNS-II)commenced in 2024.The CSNS-II linac design primarily involves the addition of a radio-frequency ion source and a section of a superconducting linear accelerator composed of two types of superconducting cavities,namely double-spoke and six-cell elliptical cavities,after the drift tube linac(DTL).The development of the double-spoke superconducting cavity began in early 2021,and by January 2023,the welding,post-processing,and vertical tests of two 324 MHz double-spoke cavity prototypes were completed,with vertical test gradients of 11.6 and 15 MV/m,and Q_(0)≥3×10^(10)@E_(acc)≤10 MV/m.The R&D of the cryomodule began in January 2022.In October 2023,the clean assembly of the double-spoke cavity string and cold mass installation of the cryomodule commenced,with the installation of the cryomodule and valve box completing in two months.In January 2024,a horizontal test of the cryomodule was completed,making it the first double-spoke cavity cryomodule in China.The test results showed that the maximum gradients of the two superconducting cavities at a pulse width of 4 ms and repetition frequency of 25 Hz were 12.8 and 15.2 MV/m,respectively.This article provides a detailed introduction to the double-spoke superconducting cavity,tuner,coupler,and cryomodule,elaborates on the clean assembly of the cavity string and cold mass installation of the cryomodule,and provides a detailed analysis of the horizontal test results.展开更多
The mineralization process of microbial-induced calcium carbonate precipitation(MICP)is influenced by many factors,and the uniformity of the calcium carbonate precipitation has become the main focus and challenge for ...The mineralization process of microbial-induced calcium carbonate precipitation(MICP)is influenced by many factors,and the uniformity of the calcium carbonate precipitation has become the main focus and challenge for MICP technology.In this study,the uniformity of the saturated calcareous sand treated with MICP was in-vestigated through one-dimensional calcareous sand column tests and model tests.The coefficient of variation was employed in one-dimensional sand column tests to investigate the impact of injection rate,cementation solution concentration,and number of injection cycles on the uniformity of the MICP treatment.Additionally,model tests were conducted to investigate the impact of injection pressure and methods on the treatment range and uniformity under three-dimensional seepage conditions.Test results demonstrate that the reinforcement strength and uniformity are significantly influenced by the injection rate of the cementation solution,with a rate of 3 mL/min,yielding a favorable treatment effect.Excessive concentration of the cementation solution can lead to significant non-uniformity and a reduction in the compressive strength of MICP-treated samples.Conversely,excessively low concentrations may result in decreased bonding efficiency.Among the four considered con-centrations,0.5 mol/L and 1 mol/L exhibit superior reinforcing effects.The morphological development of calcareous sandy foundation reinforcement is associated with the spatial distribution pattern of the bacterial solution,exhibiting a relatively larger reinforcement area in proximity to the lower region of the model and a gradually decreasing range towards the upper part.Under three-dimensional seepage conditions,in addition to the non-uniform radial cementation along the injection pipe,there is also vertical heterogeneity of cementation along the length of the injection pipe due to gravitational effects,resulting in preferential deposition of calcium carbonate at the lower section,The application of injection pressure and a double-pipe circulation injection method can mitigate the accumulation of bacterial solution and cementation solution at the bottom,thereby improving the reinforcement range and uniformity.展开更多
The lack of systematic and scientific top-level arrangement in the field of civil aircraft flight test leads to the problems of long duration and high cost.Based on the flight test activity,mathematical models of flig...The lack of systematic and scientific top-level arrangement in the field of civil aircraft flight test leads to the problems of long duration and high cost.Based on the flight test activity,mathematical models of flight test duration and cost are established to set up the framework of flight test process.The top-level arrangement for flight test is optimized by multi-objective algorithm to reduce the duration and cost of flight test.In order to verify the necessity and validity of the mathematical models and the optimization algorithm of top-level arrangement,real flight test data is used to make an example calculation.Results show that the multi-objective optimization results of the top-level flight arrangement are better than the initial arrangement data,which can shorten the duration,reduce the cost,and improve the efficiency of flight test.展开更多
Considering the challenges posed by external disturbances on carrier-based aircraft land-ing control,higher demands are required for the precision and convergence of the carrier landingcontrol system.First,this paper ...Considering the challenges posed by external disturbances on carrier-based aircraft land-ing control,higher demands are required for the precision and convergence of the carrier landingcontrol system.First,this paper proposes an Adaptive Terminal Sliding Combined Super TwistingControl(ATS-STC)method to address the issues of low precision,slow convergence,and poor dis-turbance rejection capability resulting from external disturbances,such as carrier air-wake and deckmotion.By introducing a nonlinear term into the sliding surface and employing an integralapproach,the proposed ATS-STC method can ensure finite-time convergence and mitigate the chat-tering problem.An adaptive law is also utilized to estimate the external disturbances,therebyenhancing the anti-disturbance performance.Then,the stability and convergence time analysis ofthe designed controller are conducted.Based on the proposed method,an Automatic Carrier Land-ing System(ACLS)is developed to perform the carrier landing control task.Furthermore,a multi-dimensional validation is carried out.For the numerical simulation test,the Terminal Sliding ModeControl(TSMC)method and Proportion Integration Differentiation(PID)method are introducedas comparison,the quantitative assessment results show that the tracking error of TSMC and PIDcan reach 1.5 times and 2 times that of the proposed method.Finally,the Hardware-in-the-Loop(HIL)test and real flight test are conducted.All the experimental results demonstrate that the pro-posed control method is more effective and precise.展开更多
In high-risk industrial environments like nuclear power plants,precise defect identification and localization are essential for maintaining production stability and safety.However,the complexity of such a harsh enviro...In high-risk industrial environments like nuclear power plants,precise defect identification and localization are essential for maintaining production stability and safety.However,the complexity of such a harsh environment leads to significant variations in the shape and size of the defects.To address this challenge,we propose the multivariate time series segmentation network(MSSN),which adopts a multiscale convolutional network with multi-stage and depth-separable convolutions for efficient feature extraction through variable-length templates.To tackle the classification difficulty caused by structural signal variance,MSSN employs logarithmic normalization to adjust instance distributions.Furthermore,it integrates classification with smoothing loss functions to accurately identify defect segments amid similar structural and defect signal subsequences.Our algorithm evaluated on both the Mackey-Glass dataset and industrial dataset achieves over 95%localization and demonstrates the capture capability on the synthetic dataset.In a nuclear plant's heat transfer tube dataset,it captures 90%of defect instances with75%middle localization F1 score.展开更多
In the current social environment,the importance of energy conservation and emission reduction is increasing day by day for both the country and its people.Electronic and electrical products,as important items for peo...In the current social environment,the importance of energy conservation and emission reduction is increasing day by day for both the country and its people.Electronic and electrical products,as important items for people’s production and life,require high attention from industry insiders in terms of their energy efficiency testing.Relying on energy efficiency testing can achieve the goal of energy conservation and emission reduction,and related quality control technologies will also inject new momentum into the green development of the industry.This article will discuss the practical strategies of quality control technology for energy efficiency testing of electronic and electrical products based on the significance of such testing,hoping to provide some help.展开更多
The integration of Global Navigation Satellite System(GNSS)technology into railway train control systems is a crucial step toward achieving the vision of a digital railway.Traditional train control systems undergo ext...The integration of Global Navigation Satellite System(GNSS)technology into railway train control systems is a crucial step toward achieving the vision of a digital railway.Traditional train control systems undergo extensive in-house tests and prolonged field tests for certification and approval before operational deployment,leading to high costs,delays,and operational disruptions.This paper introduces a GNSS-based train control localization framework which eliminates the need for on-site testing by leveraging train movement dynamics and 3D environment modeling to create a zero on-site testing platform.The proposed framework simulates train movement and the surrounding 3D environment using collected railway line location data and environmental attributes to generate realistic multipath signals and obscuration effects.This approach enables comprehensive laboratory-based case studies for train localization,reducing the huge amount test of needed for physical field trials.The framework is established in house,using the data collected at the Test Base of China Academy of Railway Sciences(Circular Railway).Results from the open area and cutting environment tests demonstrate high localization accuracy repeatability within the simulated environment,validating the feasibility and effectiveness of zero on-site testing for GNSS-based train control systems.This research highlights the potential of GNSS simulation platforms in enhancing cost efficiency,operational safety,and accuracy for future digital railways.展开更多
The uniaxial compressive strength(UCS)of rocks is a vital geomechanical parameter widely used for rock mass classification,stability analysis,and engineering design in rock engineering.Various UCS testing methods and ...The uniaxial compressive strength(UCS)of rocks is a vital geomechanical parameter widely used for rock mass classification,stability analysis,and engineering design in rock engineering.Various UCS testing methods and apparatuses have been proposed over the past few decades.The objective of the present study is to summarize the status and development in theories,test apparatuses,data processing of the existing testing methods for UCS measurement.It starts with elaborating the theories of these test methods.Then the test apparatus and development trends for UCS measurement are summarized,followed by a discussion on rock specimens for test apparatus,and data processing methods.Next,the method selection for UCS measurement is recommended.It reveals that the rock failure mechanism in the UCS testing methods can be divided into compression-shear,compression-tension,composite failure mode,and no obvious failure mode.The trends of these apparatuses are towards automation,digitization,precision,and multi-modal test.Two size correction methods are commonly used.One is to develop empirical correlation between the measured indices and the specimen size.The other is to use a standard specimen to calculate the size correction factor.Three to five input parameters are commonly utilized in soft computation models to predict the UCS of rocks.The selection of the test methods for the UCS measurement can be carried out according to the testing scenario and the specimen size.The engineers can gain a comprehensive understanding of the UCS testing methods and its potential developments in various rock engineering endeavors.展开更多
Microstructural heterogeneity of low-permeability sandstone roofs of deep unmineable coal seams due to diagenesis significantly affects rock mechanical behavior,greatly impacting the sealing potential of in situ CO_(2...Microstructural heterogeneity of low-permeability sandstone roofs of deep unmineable coal seams due to diagenesis significantly affects rock mechanical behavior,greatly impacting the sealing potential of in situ CO_(2) sequestration and the structural stability of the geological formation.However,little is known about how the microstructure of different mineral groups influences the multiscale mechanical behavior of deep sandstone.This study proposes a new method for quantitatively characterizing the multiscale mechanical properties of low-permeability sandstone and shows the mechanisms responsible for mechanical failure at the micro-,meso-,and macroscale.Triaxial compression tests and targeted nanoindentation tests were conducted to assess the micro-and macroscale mechanical properties of different types of sandstone.The micro-and macroscale experiments were coupled with numerical simulations of compression using a unified cohesive model based on Voronoi polygons to clarify the multiscale mechanical behavior.The results indicate that quartz,the primary mineral component of the sandstones examined,exhibits the strongest micromechanical properties,followed by feldspar,calcite,and clay minerals.Compared to polycrystalline quartz,monocrystalline quartz has a more stable microstructure and is mechanically stronger.The macro-mechanical properties of tight sandstone samples are weakened by increased microstructural inhomogeneity and larger grain size.This leads to a higher likelihood of splitting damage,characterized by a high degree of discrete and weak stress sensitivity.The major conclusion is that the positive rhythm lithofacies of medium-grained sandstone to siltstone are the most favorable for efficient CO_(2) sequestration in deep unmineable coal seams.展开更多
This article introduces the composition and working principle of home appliance control board automation testing equipment,elaborates on the importance of key technical indicators,explains the integrated design of fun...This article introduces the composition and working principle of home appliance control board automation testing equipment,elaborates on the importance of key technical indicators,explains the integrated design of functional modules,signal processing modules,and data analysis modules,and covers aspects such as the application of machine learning algorithms and the establishment of fault waveform databases.Finally,it looks forward to the development of intelligent testing systems and emphasizes the importance of building a standardized testing system.展开更多
Fluoropyrimidines(FP),including 5-fluorouracil and its prodrug capecitabine,are commonly employed in treating various solid tumors.Nonetheless,their use is frequently constrained by severe toxicities in 20%-30%of pati...Fluoropyrimidines(FP),including 5-fluorouracil and its prodrug capecitabine,are commonly employed in treating various solid tumors.Nonetheless,their use is frequently constrained by severe toxicities in 20%-30%of patients.Pharmacogenetic testing for dihydropyrimidine dehydrogenase(DPYD)deficiency,based on DPYD polymorphisms,has notably decreased severe adverse events,improving the safety of FP therapy.A recent D'Amato et al study evaluated the prevalence of DPYD polymorphisms and their effect on FP tolerability among Italian patients with gastrointestinal cancers.Although this study provided important insights into the significance of DPYD testing,its retrospective nature,inconsistency in testing DPYD variants,and lack of consideration for socioeconomic and confounding factors showed considerable limitations.Expanding the screening to include DPYD variants,addressing confounding biases through robust statistical analyses,and implementing prospective studies are critical next steps to strengthen the clinical evidence.Furthermore,the absence of a comprehensive cost-effectiveness analysis highlights the need for further financial assessments to advocate for broader implementation.We emphasized integrating DPYD-guided dosing,pre-treatment genetic counseling,and standardized testing procedures into clinical practice to improve patient outcomes and minimize treatment-related toxicities.展开更多
Working memory is a core cognitive function that supports goal-directed behavior and complex thought.We developed a spatial working memory and attention test on paired symbols(SWAPS)which has been proved to be a usefu...Working memory is a core cognitive function that supports goal-directed behavior and complex thought.We developed a spatial working memory and attention test on paired symbols(SWAPS)which has been proved to be a useful and valid tool for spatial working memory and attention studies in the fields of cognitive psychology,education,and psychiatry.The repeated administration of working memory capacity tests is common in clinical and research settings.Studies suggest that repeated cognitive tests may improve the performance scores also known as retest effects.The systematic investigation of retest effects in SWAPS is critical for interpreting scientific results,but it is still not fully developed.To address this,we recruited 77 college students aged 18–21 years and used SWAPS comprising 72 trials with different memory loads,learning time,and delay span.We repeated the test once a week for five weeks to investigate the retest effects of SWAPS.There were significant retest effects in the first two tests:the accuracy of the SWAPS tests significantly increased,and then stabilized.These findings provide useful information for researchers to appropriately use or interpret the repeated working memory tests.Further experiments are still needed to clarify the factors that mediate the retest effects,and find out the cognitive mechanism that influences the retest effects.展开更多
Shotcrete is one of the common solutions for shallow sliding.It works by forming a protective layer with high strength and cementing the loose soil particles on the slope surface to prevent shallow sliding.However,the...Shotcrete is one of the common solutions for shallow sliding.It works by forming a protective layer with high strength and cementing the loose soil particles on the slope surface to prevent shallow sliding.However,the solidification time of conventional cement paste is long when shotcrete is used to treat cohesionless soil landslide.The idea of reinforcing slope with polyurethane solidified soil(i.e.,mixture of polyurethane and sand)was proposed.Model tests and finite element analysis were carried out to study the effectiveness of the proposed new method on the emergency treatment of cohesionless soil landslide.Surcharge loading on the crest of the slope was applied step by step until landslide was triggered so as to test and compare the stability and bearing capacity of slope models with different conditions.The simulated slope displacements were relatively close to the measured results,and the simulated slope deformation characteristics were in good agreement with the observed phenomena,which verifies the accuracy of the numerical method.Under the condition of surcharge loading on the crest of the slope,the unreinforced slope slid when the surcharge loading exceeded 30 k Pa,which presented a failure mode of local instability and collapse at the shallow layer of slope top.The reinforced slope remained stable even when the surcharge loading reached 48 k Pa.The displacement of the reinforced slope was reduced by more than 95%.Overall,this study verifies the effectiveness of polyurethane in the emergency treatment of cohesionless soil landslide and should have broad application prospects in the field of geological disasters concerning the safety of people's live.展开更多
Subgrade engineering is a fundamental aspect of infrastructure construction in China.As the primary structural element responsible for bearing and distributing traffic loads,the subgrade must not only withstand the su...Subgrade engineering is a fundamental aspect of infrastructure construction in China.As the primary structural element responsible for bearing and distributing traffic loads,the subgrade must not only withstand the substantial pressures exerted by vehicles,trains,and other forms of transportation,but also efficiently transfer these loads to the underlying foundation,ensuring the stability and longevity of the roadway.In recent years,advancements in subgrade engineering technology have propelled the industry towards smarter,greener,and more sustainable practices,particularly in the areas of intelligent monitoring,disaster management,and innovative construction methods.This paper reviews the application and methodologies of intelligent testing equipment,including cone penetration testing(CPT)devices,soil resistivity testers,and intelligent rebound testers,in subgrade engineering.It examines the operating principles,advantages,limitations,and application ranges of these tools in subgrade testing.Additionally,the paper evaluates the practical use of advanced equipment from both domestic and international perspectives,addressing the challenges encountered by various instruments in realworld applications.These devices enable precise,comprehensive testing and evaluation of subgrade conditions at different stages,providing real-time data analysis and intelligent early warnings.This supports effective subgrade health management and maintenance.As intelligent technologies continue to evolve and integrate,these tools will increasingly enhance the accuracy,efficiency,and sustainability of subgrade monitoring.展开更多
基金support of this project through the Southwest Regional Partnership on Carbon Sequestration(Grant No.DE-FC26-05NT42591)Improving Production in the Emerging Paradox Oil Play(Grant No.DE-FE0031775).
文摘Geomechanical properties of rocks vary across different measurement scales,primarily due to heterogeneity.Micro-scale geomechanical tests,including micro-scale“scratch tests”and nano-scale nanoindentation tests,are attractive at different scales.Each method requires minimal sample volume,is low cost,and includes a relatively rapid measurement turnaround time.However,recent micro-scale test results–including scratch test results and nanoindentation results–exhibit tangible variance and uncertainty,suggesting a need to correlate mineral composition mapping to elastic modulus mapping to isolate the relative impact of specific minerals.Different research labs often utilize different interpretation methods,and it is clear that future micro-mechanical tests may benefit from standardized testing and interpretation procedures.The objectives of this study are to seek options for standardized testing and interpretation procedures,through two specific objectives:(1)Quantify chemical and physical controls on micro-mechanical properties and(2)Quantify the source of uncertainties associated with nanoindentation measurements.To reach these goals,we conducted mechanical tests on three different scales:triaxial compression tests,scratch tests,and nanoindentation tests.We found that mineral phase weight percentage is highly correlated with nanoindentation elastic modulus distribution.Finally,we conclude that nanoindentation testing is a mineralogy and microstructure-based method and generally yields significant uncertainty and overestimation.The uncertainty of the testing method is largely associated with not mapping pore space a priori.Lastly,the uncertainty can be reduced by combining phase mapping and modulus mapping with substantial and random data sampling.
文摘This study presents the results of a Monte Carlo simulation to compare the statistical power of Siegel-Tukey and Savage tests.The main purpose of the study is to evaluate the statistical power of both tests in scenarios involving Normal,Platykurtic and Skewed distributions over different sample sizes and standard deviation values.In the study,standard deviation ratios were set as 2,3,4,1/2,1/3 and 1/4 and power comparisons were made between small and large sample sizes.For equal sample sizes,small sample sizes of 5,8,10,12,16 and 20 and large sample sizes of 25,50,75 and 100 were used.For different sample sizes,the combinations of(4,16),(8,16),(10,20),(16,4),(16,8)and(20,10)small sample sizes and(10,30),(30,10),(50,75),(50,100),(75,50),(75,100),(100,50)and(100,75)large sample sizes were examined in detail.According to the findings,the power analysis under variance heterogeneity conditions shows that the Siegel-Tukey test has a higher statistical power than the other nonparametric Savage test at small and large sample sizes.In particular,the Siegel-Tukey test was reported to offer higher precision and power under variance heterogeneity,regardless of having equal or different sample sizes.
文摘In recent years,the application scenarios of electrical and electronic products have become increasingly diverse worldwide.The impact of climatic environmental tests on the performance of related products has attracted much attention,and formulating scientific and reasonable environmental test plans has become an important step to ensure product quality and reliability.
文摘BACKGROUND Small intestinal bacterial overgrowth(SIBO)is suspected and excluded frequently in functional gastrointestinal(GI)disorders.Children presenting with various esophago-gastro-duodenal(upper GI)symptoms are rarely subjected to investig-ations for SIBO.AIM To estimate the frequency of SIBO in children having functional upper GI sym-ptoms(as cases)and to compare the result of the SIBO status to that of the con-trols.METHODS Children aged 6 to 18 who presented with upper GI symptoms were selected for the study.All children were subjected to upper GI endoscopy before being advised of any proton pump inhibitors(PPIs).Children with normal endoscopy were assigned as cases,and children having any endoscopic lesion were design-ated as controls.Both groups were subjected to a glucose-hydrogen breath test by Bedfont Gastrolyser.RESULTS A total of 129 consecutive children who were naive to PPIs and had normal ba-seline investigations were included in the study.Among them,67 patients had endoscopic lesions and served as the control group,with six cases being excluded due to the presence of Helicobacter pylori in gastric biopsies.Sixty-two children with normal endoscopy results formed the case group.In the case group,35 children(59%)tested positive for hydrogen breath tests,compared to 13 children(21%)in the control group.The calculated odds ratio was 5.38(95%confidence interval:2.41-12.0),which was statistically significant.Further analysis of symptoms revealed that nausea,halitosis,foul-smelling eructation,and epigastric fullness were positive predictors of SIBO.CONCLUSION It is worthwhile to investigate and treat SIBO in all children presenting with upper GI symptoms that are not explained by endoscopy findings.
文摘The China Spallation Neutron Source(CSNS)is the fourth pulsed accelerator-driven neutron source in the world,and it achieved its design target of 100 kW in 2020.The planned China Spallation Neutron Source Phase II(CSNS-II)commenced in 2024.The CSNS-II linac design primarily involves the addition of a radio-frequency ion source and a section of a superconducting linear accelerator composed of two types of superconducting cavities,namely double-spoke and six-cell elliptical cavities,after the drift tube linac(DTL).The development of the double-spoke superconducting cavity began in early 2021,and by January 2023,the welding,post-processing,and vertical tests of two 324 MHz double-spoke cavity prototypes were completed,with vertical test gradients of 11.6 and 15 MV/m,and Q_(0)≥3×10^(10)@E_(acc)≤10 MV/m.The R&D of the cryomodule began in January 2022.In October 2023,the clean assembly of the double-spoke cavity string and cold mass installation of the cryomodule commenced,with the installation of the cryomodule and valve box completing in two months.In January 2024,a horizontal test of the cryomodule was completed,making it the first double-spoke cavity cryomodule in China.The test results showed that the maximum gradients of the two superconducting cavities at a pulse width of 4 ms and repetition frequency of 25 Hz were 12.8 and 15.2 MV/m,respectively.This article provides a detailed introduction to the double-spoke superconducting cavity,tuner,coupler,and cryomodule,elaborates on the clean assembly of the cavity string and cold mass installation of the cryomodule,and provides a detailed analysis of the horizontal test results.
基金support of Natural Science Foundation of China(Grant No.52108324,No.52008207,and No.52108298)for conducting this study.
文摘The mineralization process of microbial-induced calcium carbonate precipitation(MICP)is influenced by many factors,and the uniformity of the calcium carbonate precipitation has become the main focus and challenge for MICP technology.In this study,the uniformity of the saturated calcareous sand treated with MICP was in-vestigated through one-dimensional calcareous sand column tests and model tests.The coefficient of variation was employed in one-dimensional sand column tests to investigate the impact of injection rate,cementation solution concentration,and number of injection cycles on the uniformity of the MICP treatment.Additionally,model tests were conducted to investigate the impact of injection pressure and methods on the treatment range and uniformity under three-dimensional seepage conditions.Test results demonstrate that the reinforcement strength and uniformity are significantly influenced by the injection rate of the cementation solution,with a rate of 3 mL/min,yielding a favorable treatment effect.Excessive concentration of the cementation solution can lead to significant non-uniformity and a reduction in the compressive strength of MICP-treated samples.Conversely,excessively low concentrations may result in decreased bonding efficiency.Among the four considered con-centrations,0.5 mol/L and 1 mol/L exhibit superior reinforcing effects.The morphological development of calcareous sandy foundation reinforcement is associated with the spatial distribution pattern of the bacterial solution,exhibiting a relatively larger reinforcement area in proximity to the lower region of the model and a gradually decreasing range towards the upper part.Under three-dimensional seepage conditions,in addition to the non-uniform radial cementation along the injection pipe,there is also vertical heterogeneity of cementation along the length of the injection pipe due to gravitational effects,resulting in preferential deposition of calcium carbonate at the lower section,The application of injection pressure and a double-pipe circulation injection method can mitigate the accumulation of bacterial solution and cementation solution at the bottom,thereby improving the reinforcement range and uniformity.
基金supported by the National Natural Science Foundation of China(62073267,61903305)the Fundamental Research Funds for the Central Universities(HXGJXM202214).
文摘The lack of systematic and scientific top-level arrangement in the field of civil aircraft flight test leads to the problems of long duration and high cost.Based on the flight test activity,mathematical models of flight test duration and cost are established to set up the framework of flight test process.The top-level arrangement for flight test is optimized by multi-objective algorithm to reduce the duration and cost of flight test.In order to verify the necessity and validity of the mathematical models and the optimization algorithm of top-level arrangement,real flight test data is used to make an example calculation.Results show that the multi-objective optimization results of the top-level flight arrangement are better than the initial arrangement data,which can shorten the duration,reduce the cost,and improve the efficiency of flight test.
基金supported by the National Natural Science Foundation of China(No.T2288101)the National Key Research and Development Project,China(No.2020YFC1512500)the Academic Excellence Foundation of Beijing University of Aeronautics and Astronautics(BUAA)。
文摘Considering the challenges posed by external disturbances on carrier-based aircraft land-ing control,higher demands are required for the precision and convergence of the carrier landingcontrol system.First,this paper proposes an Adaptive Terminal Sliding Combined Super TwistingControl(ATS-STC)method to address the issues of low precision,slow convergence,and poor dis-turbance rejection capability resulting from external disturbances,such as carrier air-wake and deckmotion.By introducing a nonlinear term into the sliding surface and employing an integralapproach,the proposed ATS-STC method can ensure finite-time convergence and mitigate the chat-tering problem.An adaptive law is also utilized to estimate the external disturbances,therebyenhancing the anti-disturbance performance.Then,the stability and convergence time analysis ofthe designed controller are conducted.Based on the proposed method,an Automatic Carrier Land-ing System(ACLS)is developed to perform the carrier landing control task.Furthermore,a multi-dimensional validation is carried out.For the numerical simulation test,the Terminal Sliding ModeControl(TSMC)method and Proportion Integration Differentiation(PID)method are introducedas comparison,the quantitative assessment results show that the tracking error of TSMC and PIDcan reach 1.5 times and 2 times that of the proposed method.Finally,the Hardware-in-the-Loop(HIL)test and real flight test are conducted.All the experimental results demonstrate that the pro-posed control method is more effective and precise.
基金supported by the National Science and Technology Major Project of the Ministry of Science and Technology of China(2024ZD0608100)the National Natural Science Foundation of China(62332017,U22A2022)
文摘In high-risk industrial environments like nuclear power plants,precise defect identification and localization are essential for maintaining production stability and safety.However,the complexity of such a harsh environment leads to significant variations in the shape and size of the defects.To address this challenge,we propose the multivariate time series segmentation network(MSSN),which adopts a multiscale convolutional network with multi-stage and depth-separable convolutions for efficient feature extraction through variable-length templates.To tackle the classification difficulty caused by structural signal variance,MSSN employs logarithmic normalization to adjust instance distributions.Furthermore,it integrates classification with smoothing loss functions to accurately identify defect segments amid similar structural and defect signal subsequences.Our algorithm evaluated on both the Mackey-Glass dataset and industrial dataset achieves over 95%localization and demonstrates the capture capability on the synthetic dataset.In a nuclear plant's heat transfer tube dataset,it captures 90%of defect instances with75%middle localization F1 score.
文摘In the current social environment,the importance of energy conservation and emission reduction is increasing day by day for both the country and its people.Electronic and electrical products,as important items for people’s production and life,require high attention from industry insiders in terms of their energy efficiency testing.Relying on energy efficiency testing can achieve the goal of energy conservation and emission reduction,and related quality control technologies will also inject new momentum into the green development of the industry.This article will discuss the practical strategies of quality control technology for energy efficiency testing of electronic and electrical products based on the significance of such testing,hoping to provide some help.
基金supported by the National Natural Science Foundation of China(62027809,U2268206,T2222015,U2468202).
文摘The integration of Global Navigation Satellite System(GNSS)technology into railway train control systems is a crucial step toward achieving the vision of a digital railway.Traditional train control systems undergo extensive in-house tests and prolonged field tests for certification and approval before operational deployment,leading to high costs,delays,and operational disruptions.This paper introduces a GNSS-based train control localization framework which eliminates the need for on-site testing by leveraging train movement dynamics and 3D environment modeling to create a zero on-site testing platform.The proposed framework simulates train movement and the surrounding 3D environment using collected railway line location data and environmental attributes to generate realistic multipath signals and obscuration effects.This approach enables comprehensive laboratory-based case studies for train localization,reducing the huge amount test of needed for physical field trials.The framework is established in house,using the data collected at the Test Base of China Academy of Railway Sciences(Circular Railway).Results from the open area and cutting environment tests demonstrate high localization accuracy repeatability within the simulated environment,validating the feasibility and effectiveness of zero on-site testing for GNSS-based train control systems.This research highlights the potential of GNSS simulation platforms in enhancing cost efficiency,operational safety,and accuracy for future digital railways.
基金the National Natural Science Foundation of China(Grant Nos.52308403 and 52079068)the Yunlong Lake Laboratory of Deep Underground Science and Engineering(No.104023005)the China Postdoctoral Science Foundation(Grant No.2023M731998)for funding provided to this work.
文摘The uniaxial compressive strength(UCS)of rocks is a vital geomechanical parameter widely used for rock mass classification,stability analysis,and engineering design in rock engineering.Various UCS testing methods and apparatuses have been proposed over the past few decades.The objective of the present study is to summarize the status and development in theories,test apparatuses,data processing of the existing testing methods for UCS measurement.It starts with elaborating the theories of these test methods.Then the test apparatus and development trends for UCS measurement are summarized,followed by a discussion on rock specimens for test apparatus,and data processing methods.Next,the method selection for UCS measurement is recommended.It reveals that the rock failure mechanism in the UCS testing methods can be divided into compression-shear,compression-tension,composite failure mode,and no obvious failure mode.The trends of these apparatuses are towards automation,digitization,precision,and multi-modal test.Two size correction methods are commonly used.One is to develop empirical correlation between the measured indices and the specimen size.The other is to use a standard specimen to calculate the size correction factor.Three to five input parameters are commonly utilized in soft computation models to predict the UCS of rocks.The selection of the test methods for the UCS measurement can be carried out according to the testing scenario and the specimen size.The engineers can gain a comprehensive understanding of the UCS testing methods and its potential developments in various rock engineering endeavors.
基金supported by the project from the Exploration and Development Research Institute of PetroChina Daqing Oilfield Companyfinancial support from the research by the National Natural Science Foundation of China(42402148)+1 种基金Sichuan Provincial Fund(24NSFSC4997)Guizhou Outstanding Young Science and Technology Talent Program(YQK[2023]012).
文摘Microstructural heterogeneity of low-permeability sandstone roofs of deep unmineable coal seams due to diagenesis significantly affects rock mechanical behavior,greatly impacting the sealing potential of in situ CO_(2) sequestration and the structural stability of the geological formation.However,little is known about how the microstructure of different mineral groups influences the multiscale mechanical behavior of deep sandstone.This study proposes a new method for quantitatively characterizing the multiscale mechanical properties of low-permeability sandstone and shows the mechanisms responsible for mechanical failure at the micro-,meso-,and macroscale.Triaxial compression tests and targeted nanoindentation tests were conducted to assess the micro-and macroscale mechanical properties of different types of sandstone.The micro-and macroscale experiments were coupled with numerical simulations of compression using a unified cohesive model based on Voronoi polygons to clarify the multiscale mechanical behavior.The results indicate that quartz,the primary mineral component of the sandstones examined,exhibits the strongest micromechanical properties,followed by feldspar,calcite,and clay minerals.Compared to polycrystalline quartz,monocrystalline quartz has a more stable microstructure and is mechanically stronger.The macro-mechanical properties of tight sandstone samples are weakened by increased microstructural inhomogeneity and larger grain size.This leads to a higher likelihood of splitting damage,characterized by a high degree of discrete and weak stress sensitivity.The major conclusion is that the positive rhythm lithofacies of medium-grained sandstone to siltstone are the most favorable for efficient CO_(2) sequestration in deep unmineable coal seams.
文摘This article introduces the composition and working principle of home appliance control board automation testing equipment,elaborates on the importance of key technical indicators,explains the integrated design of functional modules,signal processing modules,and data analysis modules,and covers aspects such as the application of machine learning algorithms and the establishment of fault waveform databases.Finally,it looks forward to the development of intelligent testing systems and emphasizes the importance of building a standardized testing system.
文摘Fluoropyrimidines(FP),including 5-fluorouracil and its prodrug capecitabine,are commonly employed in treating various solid tumors.Nonetheless,their use is frequently constrained by severe toxicities in 20%-30%of patients.Pharmacogenetic testing for dihydropyrimidine dehydrogenase(DPYD)deficiency,based on DPYD polymorphisms,has notably decreased severe adverse events,improving the safety of FP therapy.A recent D'Amato et al study evaluated the prevalence of DPYD polymorphisms and their effect on FP tolerability among Italian patients with gastrointestinal cancers.Although this study provided important insights into the significance of DPYD testing,its retrospective nature,inconsistency in testing DPYD variants,and lack of consideration for socioeconomic and confounding factors showed considerable limitations.Expanding the screening to include DPYD variants,addressing confounding biases through robust statistical analyses,and implementing prospective studies are critical next steps to strengthen the clinical evidence.Furthermore,the absence of a comprehensive cost-effectiveness analysis highlights the need for further financial assessments to advocate for broader implementation.We emphasized integrating DPYD-guided dosing,pre-treatment genetic counseling,and standardized testing procedures into clinical practice to improve patient outcomes and minimize treatment-related toxicities.
基金the National Natural Science Foundation of China(No.91632103)the Shanghai Education Commission Research and Innovation Program(No.2019-01-07-00-02-E00037)+2 种基金the Program of Shanghai Subject Chief Scientist(No.17XD1401700)the Higher Education Disciplinary Innovation Programthe“Eastern Scholar”Project。
文摘Working memory is a core cognitive function that supports goal-directed behavior and complex thought.We developed a spatial working memory and attention test on paired symbols(SWAPS)which has been proved to be a useful and valid tool for spatial working memory and attention studies in the fields of cognitive psychology,education,and psychiatry.The repeated administration of working memory capacity tests is common in clinical and research settings.Studies suggest that repeated cognitive tests may improve the performance scores also known as retest effects.The systematic investigation of retest effects in SWAPS is critical for interpreting scientific results,but it is still not fully developed.To address this,we recruited 77 college students aged 18–21 years and used SWAPS comprising 72 trials with different memory loads,learning time,and delay span.We repeated the test once a week for five weeks to investigate the retest effects of SWAPS.There were significant retest effects in the first two tests:the accuracy of the SWAPS tests significantly increased,and then stabilized.These findings provide useful information for researchers to appropriately use or interpret the repeated working memory tests.Further experiments are still needed to clarify the factors that mediate the retest effects,and find out the cognitive mechanism that influences the retest effects.
基金the financial support from the Fujian Science Foundation for Outstanding Youth(2023J06039)the National Natural Science Foundation of China(Grant No.41977259,U2005205,41972268)the Independent Research Project of Technology Innovation Center for Monitoring and Restoration Engineering of Ecological Fragile Zone in Southeast China(KY-090000-04-2022-019)。
文摘Shotcrete is one of the common solutions for shallow sliding.It works by forming a protective layer with high strength and cementing the loose soil particles on the slope surface to prevent shallow sliding.However,the solidification time of conventional cement paste is long when shotcrete is used to treat cohesionless soil landslide.The idea of reinforcing slope with polyurethane solidified soil(i.e.,mixture of polyurethane and sand)was proposed.Model tests and finite element analysis were carried out to study the effectiveness of the proposed new method on the emergency treatment of cohesionless soil landslide.Surcharge loading on the crest of the slope was applied step by step until landslide was triggered so as to test and compare the stability and bearing capacity of slope models with different conditions.The simulated slope displacements were relatively close to the measured results,and the simulated slope deformation characteristics were in good agreement with the observed phenomena,which verifies the accuracy of the numerical method.Under the condition of surcharge loading on the crest of the slope,the unreinforced slope slid when the surcharge loading exceeded 30 k Pa,which presented a failure mode of local instability and collapse at the shallow layer of slope top.The reinforced slope remained stable even when the surcharge loading reached 48 k Pa.The displacement of the reinforced slope was reduced by more than 95%.Overall,this study verifies the effectiveness of polyurethane in the emergency treatment of cohesionless soil landslide and should have broad application prospects in the field of geological disasters concerning the safety of people's live.
基金supported by the National Natural Science Foundation of China for Distinguished Young Scholars(Grant No.42225206)National Natural Science Foundation of China(42207180,42477209,42302320).
文摘Subgrade engineering is a fundamental aspect of infrastructure construction in China.As the primary structural element responsible for bearing and distributing traffic loads,the subgrade must not only withstand the substantial pressures exerted by vehicles,trains,and other forms of transportation,but also efficiently transfer these loads to the underlying foundation,ensuring the stability and longevity of the roadway.In recent years,advancements in subgrade engineering technology have propelled the industry towards smarter,greener,and more sustainable practices,particularly in the areas of intelligent monitoring,disaster management,and innovative construction methods.This paper reviews the application and methodologies of intelligent testing equipment,including cone penetration testing(CPT)devices,soil resistivity testers,and intelligent rebound testers,in subgrade engineering.It examines the operating principles,advantages,limitations,and application ranges of these tools in subgrade testing.Additionally,the paper evaluates the practical use of advanced equipment from both domestic and international perspectives,addressing the challenges encountered by various instruments in realworld applications.These devices enable precise,comprehensive testing and evaluation of subgrade conditions at different stages,providing real-time data analysis and intelligent early warnings.This supports effective subgrade health management and maintenance.As intelligent technologies continue to evolve and integrate,these tools will increasingly enhance the accuracy,efficiency,and sustainability of subgrade monitoring.
