More studies have indicated that polysaccharide sulfate has anti-coagulant activity.Now,heparin is the most popular anticoagulant used in clinic,however,its side effects have also caused highly concern.It is still und...More studies have indicated that polysaccharide sulfate has anti-coagulant activity.Now,heparin is the most popular anticoagulant used in clinic,however,its side effects have also caused highly concern.It is still under intensive investigations to synthesize effective safe polysaccharide sulfate as heparin substitute.We extracted water-soluble polysaccharide from fermented mycelium of edible polyporus albicans（Imaz.） teng,and got the water-soluble polyporus albicans teng sulfate（PATS） by modifying the water-solubility polyose with the method of chlorosulfonic acid-pyridine.The anti-coagulant assay of PATS in vitro towards normal human plasma indicates its remarkable anticoagulant activity,while the dose could be as low as 5 mg/L for anticoagulation.The anti-coagulant effect was equivalent to that of heparin about 150 U when the concentration of PATS was 10 mg/L.The study on anti-coagulation mechanism suggests that PATS got involved in the intrinsic pathway.The anti-coagulation activity of PATS was due to the inhibition of the coagulation factors IIa and Xa activities mediated by antithrombin Ⅲ（ATIII）.The anti-coagulation mechanism of PATS is absolutely identical to that of heparin.In conclusion,we suggest that PATS has the similar anti-coagulation characteristic to heparin,but with a better anti-coagulation effect.Meanwhile,derived from edible fungus-polysaccharide,PATS has more bio-safety advantage.Therefore,PATS has promising future to be developed and used as an ideal substitute for heparin in clinic.展开更多
Raindrops contain abundant renewable energy including both kinetic energy and electrostatic energy,and how to effectively harvest it becomes a hot research topic.Recently,a triboelectric nanogenerator(TENG)using liqui...Raindrops contain abundant renewable energy including both kinetic energy and electrostatic energy,and how to effectively harvest it becomes a hot research topic.Recently,a triboelectric nanogenerator(TENG)using liquid-solid contact electrification has been demonstrated for achieving an ultra-high instantaneous power output.However,when harvesting the energy from the dense raindrops instead of a single droplet,a more rational structure to eliminate the mutual influence of individual generation units is needed for maximize the output.In this work,a“solar panel-like”bridge array generators(BAGs)is proposed.By adopting array lower electrodes(ALE)and bridge reflux structure(BRS),BAGs could minimize the sharp drop in the peak power output for large-scale energy harvesting devices.When the area of the raindrop energy harvesting device is 15×15 cm2,the peak power output of BAGs reached 200 W/m2,which is remarkable for paving a potential industrial approach for effective harvesting raindrop energy at a large scale.展开更多
Background:This study aims to explore the therapeutic effects of the Qi Teng Mai Ning recipe on ischemic stroke and vascular cognitive impairment through its potential to modulate cellular autophagy,with a focus on id...Background:This study aims to explore the therapeutic effects of the Qi Teng Mai Ning recipe on ischemic stroke and vascular cognitive impairment through its potential to modulate cellular autophagy,with a focus on identifying its active ingredients and their target proteins.Methods:The study began with the identification of active ingredients in the Qi Teng Mai Ning recipe.It proceeded to screen the gene expression omnibus database for ischemic stroke and vascular cognitive impairment-associated differentially expressed mRNAs and to identify cellular autophagy-related proteins via the Human Autophagy Database.These proteins were annotated with Gene Ontology and Kyoto Encyclopedia of Genes and Genomes functions and subjected to molecular docking with the recipe’s core active ingredients.In vitro cell experiments were conducted on hypoxic HT22 cells,involving CCK8 assay,lentiviral transfection to silence autophagy related 9B(ATG9B),immunofluorescence staining,and qPCR validation to investigate the effects of the recipe on autophagy.Results:The analysis identified 104 active ingredients targeting 408 proteins and forming a complex ingredient-target network.Intersecting 55 ischemic stroke-related and 909 vascular cognitive impairment-related differentially expressed mRNAs revealed 14 co-expressed mRNAs.Molecular docking showed quercetin,kaempferol,myrcene,and conferone as key ingredients targeting autophagy-related proteins.Cellular experiments indicated that the recipe significantly enhanced cell viability under hypoxic conditions,reduced apoptosis,and modulated the expression of autophagy-related factors,thereby decreasing apoptosis rates in HT22 cells.Conclusion:The Qi Teng Mai Ning recipe offers protective effects against ischemic stroke and vascular cognitive impairment by modulating autophagy-related proteins.Its efficacy highlights the potential of traditional Chinese medicine in treating these conditions,though further research is needed to fully understand its mechanisms and clinical applications.展开更多
Objecrive:To investigate the expression of TNF-αand NF-κB in the uterus of chronic pelvic inflammatory disease(CPID)model rats.Methods:40 female rats that adaptive fed for 5 days were randomly divided into normal gr...Objecrive:To investigate the expression of TNF-αand NF-κB in the uterus of chronic pelvic inflammatory disease(CPID)model rats.Methods:40 female rats that adaptive fed for 5 days were randomly divided into normal group,model group,high dose group,medium dose group and low dosegroup.In addition to the normal group:the rats in each group were made chronic pelvic inflammatory model by mechanical injuuy combined with implantation of bacteria.The rats in each group were administrated by gavage for 20days.After the last administration,the level of TNF-αand NF-κB in serum was measured by ELASA method.Results:(1)after the establishment of the model,the uterus of the chronic pelvic inflammatory model rats showed the pathological damage of chroic infilammation;the levels of lNF-αand NF-κB inserum were higher than those in the normal group,the difference was statistically significant(P<0.05).(2)After the drug intervention,the uterine tissue morphology of the rats in the Zhuang Yi Liu Fang Teng Fang Group was basically restored to normal,with only a small amount of inflammatory cell infiltration and other pathological changes;compared with the rats in the model group,the TNF-αin serum of the rats in each treatment group was lower,the difference was statistically significant(P<0.05).The expression of NF-κB in serum of each treatment group was lower fthan that of the model group(P<0.05).Conclusion:Zhuang Yi Liu Teng Fang can efectively improve the endometrial histomorphology of CPID model rats,and regulate the levels of TNF-αand NF-κB in the uterus of chronic pelvic inflammatory model rats.展开更多
The Teng people are an ethnic group who live in the boundary area of Tibet.For various reasons,the survey of ethnic minorities in China.conducted in the 1950s,excluded the Teng people. Nevertheless,the products,the li...The Teng people are an ethnic group who live in the boundary area of Tibet.For various reasons,the survey of ethnic minorities in China.conducted in the 1950s,excluded the Teng people. Nevertheless,the products,the lifestyle and even the culture of the Teng people are unique amongst ethnic Tibetan.Moinpa, and Lhopa.They are,therefore,named as the"Teng people".展开更多
Triboelectric nanogenerators(TENGS)represent a cutting-edge class of devices for energy conversion and self-powered sensing.The selection of appror priate triboelectric and conductive materials is critical in determin...Triboelectric nanogenerators(TENGS)represent a cutting-edge class of devices for energy conversion and self-powered sensing.The selection of appror priate triboelectric and conductive materials is critical in determining the performance of TENGS.In recent years,MXenes,particularly T,C,MXenes,have emerged as promising candidates for triboelectric/conductive materials in TENGS.To elucidate the multifaceted roles of MXenes,this review examines their applications from a materials science perspective.The applications are categorized into four types based on the functional layers of TENGS where MXenes are applied:(1)MXene films as conductive laye rs,(2)MXene films as triboelectric layers,(3)MXene nanosheets as fillers in polymer-based triboelectric layers,and(4)MXene films as charge trapping layers.The rationale and advantages of utilizi ng MXenes in each application are analyzed and elucidated.Owing to their unique combination of properties,including electronegativity,electrical conductivity,and flexibility,MXenes demonstrate remarkable versatility in all functional layers,either as pure films or composite films.Systematic analysis reveals that MXene composite films are particularly promising for various applications.This review represents the first comprehensive attempt to classify MXene applications in TENGS and articulate their inherent advantages,thereby providing a foundation for the design and development of high-performance MXene-based TENGS.展开更多
Since their birth in 2012,triboelectric nanogenerators(TENGs)have demonstrated astonishing development potential in the fields of energy,sensing,and advanced materials science.The capability of TENGs to convert high-e...Since their birth in 2012,triboelectric nanogenerators(TENGs)have demonstrated astonishing development potential in the fields of energy,sensing,and advanced materials science.The capability of TENGs to convert high-entropy energy into electrical signals has led to technological breakthroughs in multiple domains.In the field of energy harvesting,TENGs have moved beyond conventional fluid energy harvesting,harvesting energy even from slow,low-frequency fluid motion.This has given them significant advantages in distributed energy scenarios.In the field of intelligent sensing,TENG-based sensors have achieved high sensitivity,driving advancements in the industrial Internet of Things and environmental monitoring.High-voltage output(tens of kilovolts)and contact electrification are two characteristics of TENGs.Based on these two characteristics,TENGs can be used to develop new high-voltage power sources and interface probe applications.This topical review introduces the working principles and theoretical foundations of TENGs and then presents four of their cutting-edge applications:fluid energy harvesting,self-adaptive sensors and systems,high-voltage power sources,and interface probes.Finally,the current challenges faced by TENGs in these fields are discussed,and some solutions are offered.This review not only provides a comprehensive overview of the latest applications of TENGs but also offers guidance for their future development.展开更多
Triboelectric nanogenerators(TENGs)are promising for self-powered biomedical applications such as wound healing,cancer therapy,and biosensing.However,their dependence on external wires and electrodes limits usability ...Triboelectric nanogenerators(TENGs)are promising for self-powered biomedical applications such as wound healing,cancer therapy,and biosensing.However,their dependence on external wires and electrodes limits usability and comfort.Here,we introduce a wire-free approach using dermal conductive tattoos.Unlike conventional systems requiring a back conductor,our method uses skin as the triboelectric layer,with charge transferred via subdermal conductive tattoos—eliminating external accessories.This concept was validated through triboelectric testing of skin,tattoo performance on artificial models,bioresorbable ink development,and in vivo voltage generation.The system successfully accelerated wound healing in freely walking animals,powered solely by body motion.The use of bioresorbable zinc-based inks enabled temporary functionality that disappeared naturally with the healing process.Furthermore,the tattooed electrodes can be seamlessly merged with artistic designs,paving the way for next-generation bioelectronic tattoos that are both therapeutic and aesthetically personalized.展开更多
Objective： By applying moxibustion to the eight confluent points in different periods of time, to observe the changes in thermal pain threshold latency of acupoints based on Fei Teng Ba Fa. Methods： A total of 468 h...Objective： By applying moxibustion to the eight confluent points in different periods of time, to observe the changes in thermal pain threshold latency of acupoints based on Fei Teng Ba Fa. Methods： A total of 468 healthy college student volunteers received moxibustion at the eight confluent points in three different periods of time, i.e. Chen （7：00-9：00）, Wu （11：00-13：00） and Xu （19：00-21：00）. The thermal pain threshold latency was adopted to measure the changes in pain threshold of the eight confluent points under different conditions （different periods of time, different genders, different acupoints and different states of the acupoints） based on Fei Teng Ba Fa. Results： Finally, thirty subjects dropped out and 438 subjects were included. The comparison of thermal pain threshold latencies of the eight confluent points in the same opening or closing state based on Fei Teng Ba Fa： latencies of the closing points and adjunct points were significantly different in different periods of time （P〈0.05）, the latencies of the males were significantly longer than those of the females （P〈0.05）; there was no significant difference in the latency between the left and right sides （P〉0.05）; in the female group, there was a significant difference in the latency between the lower-limb points and the upper-limb points （P〈0.05）. The comparison of thermal point threshold latencies of the eight confluent points in different opening or closing state： in the period of Wu （11：00-13：00）, the latencies of the opening points were significantly longer than those of the closing points and adjunct points （P〈0.05）; for men, their opening and closing points had significantly longer thermal pain threshold latencies than their adjunct points （P〈0.05）; despite the gender, the latencies of the upper limb opening and closing points were significantly longer than the latency of the adjunct points （P〈0.05）; in the female group, the latencies of the lower-limb opening points were significantly shorter than those of the lower-limb closing and adjunct points （P〈0.05）. Conclusion： Based on Fei Teng Ba Fa, the pain thresholds of the eight confluent points vary in different periods of time, gender, acupoint location and opening/closing state, which can be taken as the evidence of making time-based acu puncture-moxibustion prescriptions.展开更多
Portable power is an effective solution to realize self-powered sensors for wearable devices,promoting future sustainable development.Membrane-based triboelectric nanogenerators(M-TENGs)have emerged as a promising tec...Portable power is an effective solution to realize self-powered sensors for wearable devices,promoting future sustainable development.Membrane-based triboelectric nanogenerators(M-TENGs)have emerged as a promising technology for harvesting biomechanical energy from human motion owing to their advantages,such as simple structure,lightweight design,and efficient energy conversion.However,the poor durability,low adaptability,and un-washability of two-dimensional membrane materials have largely hindered their application in wearable electronics.In this study,we propose a sheath-core polyvinylidene fluoride(PVDF)/graphene(G)-carbon fiber(CF)yarn fabricated via conjugate electrospinning,comprising a commercial CF core and an electrospun graphene-doped PVDF sheath,which improves the fatigue resistance of electrospun nanofiber films under prolonged friction and keeps a high degree of freedom.The resulting electronic textile,woven with the large-scale electrospun PVDF/G-CF yarn,demonstrates a remarkable power density of 25.5 mW·m^(-2).The tight distribution of PVDF/G nanofibers on the textile surface ensures excellent softness,washability,and durability.Furthermore,the electrospun PVDF/G-CF textile exhibits significant potential in pressure sensing,self-powered operation,and motion detection,making it highly suitable for wearable electronics applications.展开更多
Recently,the triboelectric nanogenerator(TENG)has been widely studied for the development of flexible and wearable electronics.Among the various methods for TENG modification,melting nearfield direct writing is a new ...Recently,the triboelectric nanogenerator(TENG)has been widely studied for the development of flexible and wearable electronics.Among the various methods for TENG modification,melting nearfield direct writing is a new method to fabricate solid-liquid TENG.Here,the electrospun PCL was introduced with traditional polymers to fabricate the compound solid triboelectric layer,and water,dimethicone and GaIn were chosen as the liquid triboelectric layers.In this paper,the solid substrate effect,temperature gradient effect,and the liquid substrate effect were compared in terms of TENGs.A free-standing model of TENG is employed in this paper,and the charge generated by the PCL-PI composite solid triboelectrical solid layer is more than 10 times higher than the pristine one,showing the high charge generating ability to melt near-field direct written microfibers.Furthermore,detailed investigation will be discussed how we can get a high the out-circuit voltage and short-circuit current.展开更多
Water-solid triboelectric nanogenerators(TENGs),as new energy collection devices,have attracted increasing attention in ocean energy harvesting and selfpowered sensing.Polyacrylic acid(PAA)coating,usually used on the ...Water-solid triboelectric nanogenerators(TENGs),as new energy collection devices,have attracted increasing attention in ocean energy harvesting and selfpowered sensing.Polyacrylic acid(PAA)coating,usually used on the surface of marine equipment,has the property of anti-aging and anti-wear but limits triboelectrical output when used with TENGs.In this paper,polyacrylic acid coating was modified with fluorinated polyacrylate resin(F-PAA)to increase its triboelectrical output,by 6 times,and also to increase its anti-corrosion property.In addition,the corrosion resistance property can be further enhanced by cathodic protection using the electrical output generated by the water-flow triboelectrical energy transfer process.Given their easy fabrication,water-flow energy harvesting,and corrosion resistance,PAA/F-PAA coating-based TENGs have promising applications in river and ocean energy collection and corrosion protection.展开更多
文摘More studies have indicated that polysaccharide sulfate has anti-coagulant activity.Now,heparin is the most popular anticoagulant used in clinic,however,its side effects have also caused highly concern.It is still under intensive investigations to synthesize effective safe polysaccharide sulfate as heparin substitute.We extracted water-soluble polysaccharide from fermented mycelium of edible polyporus albicans（Imaz.） teng,and got the water-soluble polyporus albicans teng sulfate（PATS） by modifying the water-solubility polyose with the method of chlorosulfonic acid-pyridine.The anti-coagulant assay of PATS in vitro towards normal human plasma indicates its remarkable anticoagulant activity,while the dose could be as low as 5 mg/L for anticoagulation.The anti-coagulant effect was equivalent to that of heparin about 150 U when the concentration of PATS was 10 mg/L.The study on anti-coagulation mechanism suggests that PATS got involved in the intrinsic pathway.The anti-coagulation activity of PATS was due to the inhibition of the coagulation factors IIa and Xa activities mediated by antithrombin Ⅲ（ATIII）.The anti-coagulation mechanism of PATS is absolutely identical to that of heparin.In conclusion,we suggest that PATS has the similar anti-coagulation characteristic to heparin,but with a better anti-coagulation effect.Meanwhile,derived from edible fungus-polysaccharide,PATS has more bio-safety advantage.Therefore,PATS has promising future to be developed and used as an ideal substitute for heparin in clinic.
基金supported in part by the National Natural Science Foundation of China(NSFC)under Grant No.52007095 and in part by NSFC under Grant No.51977118.
文摘Raindrops contain abundant renewable energy including both kinetic energy and electrostatic energy,and how to effectively harvest it becomes a hot research topic.Recently,a triboelectric nanogenerator(TENG)using liquid-solid contact electrification has been demonstrated for achieving an ultra-high instantaneous power output.However,when harvesting the energy from the dense raindrops instead of a single droplet,a more rational structure to eliminate the mutual influence of individual generation units is needed for maximize the output.In this work,a“solar panel-like”bridge array generators(BAGs)is proposed.By adopting array lower electrodes(ALE)and bridge reflux structure(BRS),BAGs could minimize the sharp drop in the peak power output for large-scale energy harvesting devices.When the area of the raindrop energy harvesting device is 15×15 cm2,the peak power output of BAGs reached 200 W/m2,which is remarkable for paving a potential industrial approach for effective harvesting raindrop energy at a large scale.
文摘Background:This study aims to explore the therapeutic effects of the Qi Teng Mai Ning recipe on ischemic stroke and vascular cognitive impairment through its potential to modulate cellular autophagy,with a focus on identifying its active ingredients and their target proteins.Methods:The study began with the identification of active ingredients in the Qi Teng Mai Ning recipe.It proceeded to screen the gene expression omnibus database for ischemic stroke and vascular cognitive impairment-associated differentially expressed mRNAs and to identify cellular autophagy-related proteins via the Human Autophagy Database.These proteins were annotated with Gene Ontology and Kyoto Encyclopedia of Genes and Genomes functions and subjected to molecular docking with the recipe’s core active ingredients.In vitro cell experiments were conducted on hypoxic HT22 cells,involving CCK8 assay,lentiviral transfection to silence autophagy related 9B(ATG9B),immunofluorescence staining,and qPCR validation to investigate the effects of the recipe on autophagy.Results:The analysis identified 104 active ingredients targeting 408 proteins and forming a complex ingredient-target network.Intersecting 55 ischemic stroke-related and 909 vascular cognitive impairment-related differentially expressed mRNAs revealed 14 co-expressed mRNAs.Molecular docking showed quercetin,kaempferol,myrcene,and conferone as key ingredients targeting autophagy-related proteins.Cellular experiments indicated that the recipe significantly enhanced cell viability under hypoxic conditions,reduced apoptosis,and modulated the expression of autophagy-related factors,thereby decreasing apoptosis rates in HT22 cells.Conclusion:The Qi Teng Mai Ning recipe offers protective effects against ischemic stroke and vascular cognitive impairment by modulating autophagy-related proteins.Its efficacy highlights the potential of traditional Chinese medicine in treating these conditions,though further research is needed to fully understand its mechanisms and clinical applications.
基金Collaborative Innovation Center of Zhuang and Yao Ethnic Medicine,No.:Gui Jiao Ke Yan〔2013〕20Guangxi first-class discipline construction project(No.Gui Jiao Ke Yan[2018]12)+1 种基金Open Project for Guangxi First-class Discipline Constuction of GuangxiUniversity of Chinese Medicine(No.2019XK038)Funded by Development Program of High-level Talent Team under Qihuang Project of Guangxi University of Chinese Medicine(No.2018005).
文摘Objecrive:To investigate the expression of TNF-αand NF-κB in the uterus of chronic pelvic inflammatory disease(CPID)model rats.Methods:40 female rats that adaptive fed for 5 days were randomly divided into normal group,model group,high dose group,medium dose group and low dosegroup.In addition to the normal group:the rats in each group were made chronic pelvic inflammatory model by mechanical injuuy combined with implantation of bacteria.The rats in each group were administrated by gavage for 20days.After the last administration,the level of TNF-αand NF-κB in serum was measured by ELASA method.Results:(1)after the establishment of the model,the uterus of the chronic pelvic inflammatory model rats showed the pathological damage of chroic infilammation;the levels of lNF-αand NF-κB inserum were higher than those in the normal group,the difference was statistically significant(P<0.05).(2)After the drug intervention,the uterine tissue morphology of the rats in the Zhuang Yi Liu Fang Teng Fang Group was basically restored to normal,with only a small amount of inflammatory cell infiltration and other pathological changes;compared with the rats in the model group,the TNF-αin serum of the rats in each treatment group was lower,the difference was statistically significant(P<0.05).The expression of NF-κB in serum of each treatment group was lower fthan that of the model group(P<0.05).Conclusion:Zhuang Yi Liu Teng Fang can efectively improve the endometrial histomorphology of CPID model rats,and regulate the levels of TNF-αand NF-κB in the uterus of chronic pelvic inflammatory model rats.
文摘The Teng people are an ethnic group who live in the boundary area of Tibet.For various reasons,the survey of ethnic minorities in China.conducted in the 1950s,excluded the Teng people. Nevertheless,the products,the lifestyle and even the culture of the Teng people are unique amongst ethnic Tibetan.Moinpa, and Lhopa.They are,therefore,named as the"Teng people".
基金supported by the National Natural Science Foundation of China(No.52372284)the Natural Science Foundation of Henan Province(No.232300421135).
文摘Triboelectric nanogenerators(TENGS)represent a cutting-edge class of devices for energy conversion and self-powered sensing.The selection of appror priate triboelectric and conductive materials is critical in determining the performance of TENGS.In recent years,MXenes,particularly T,C,MXenes,have emerged as promising candidates for triboelectric/conductive materials in TENGS.To elucidate the multifaceted roles of MXenes,this review examines their applications from a materials science perspective.The applications are categorized into four types based on the functional layers of TENGS where MXenes are applied:(1)MXene films as conductive laye rs,(2)MXene films as triboelectric layers,(3)MXene nanosheets as fillers in polymer-based triboelectric layers,and(4)MXene films as charge trapping layers.The rationale and advantages of utilizi ng MXenes in each application are analyzed and elucidated.Owing to their unique combination of properties,including electronegativity,electrical conductivity,and flexibility,MXenes demonstrate remarkable versatility in all functional layers,either as pure films or composite films.Systematic analysis reveals that MXene composite films are particularly promising for various applications.This review represents the first comprehensive attempt to classify MXene applications in TENGS and articulate their inherent advantages,thereby providing a foundation for the design and development of high-performance MXene-based TENGS.
基金supported by the National Natural Science Foundation of China(Grant No.52277227).
文摘Since their birth in 2012,triboelectric nanogenerators(TENGs)have demonstrated astonishing development potential in the fields of energy,sensing,and advanced materials science.The capability of TENGs to convert high-entropy energy into electrical signals has led to technological breakthroughs in multiple domains.In the field of energy harvesting,TENGs have moved beyond conventional fluid energy harvesting,harvesting energy even from slow,low-frequency fluid motion.This has given them significant advantages in distributed energy scenarios.In the field of intelligent sensing,TENG-based sensors have achieved high sensitivity,driving advancements in the industrial Internet of Things and environmental monitoring.High-voltage output(tens of kilovolts)and contact electrification are two characteristics of TENGs.Based on these two characteristics,TENGs can be used to develop new high-voltage power sources and interface probe applications.This topical review introduces the working principles and theoretical foundations of TENGs and then presents four of their cutting-edge applications:fluid energy harvesting,self-adaptive sensors and systems,high-voltage power sources,and interface probes.Finally,the current challenges faced by TENGs in these fields are discussed,and some solutions are offered.This review not only provides a comprehensive overview of the latest applications of TENGs but also offers guidance for their future development.
基金funded by Iran National Science Foundation(INSF)under project no.4022012.
文摘Triboelectric nanogenerators(TENGs)are promising for self-powered biomedical applications such as wound healing,cancer therapy,and biosensing.However,their dependence on external wires and electrodes limits usability and comfort.Here,we introduce a wire-free approach using dermal conductive tattoos.Unlike conventional systems requiring a back conductor,our method uses skin as the triboelectric layer,with charge transferred via subdermal conductive tattoos—eliminating external accessories.This concept was validated through triboelectric testing of skin,tattoo performance on artificial models,bioresorbable ink development,and in vivo voltage generation.The system successfully accelerated wound healing in freely walking animals,powered solely by body motion.The use of bioresorbable zinc-based inks enabled temporary functionality that disappeared naturally with the healing process.Furthermore,the tattooed electrodes can be seamlessly merged with artistic designs,paving the way for next-generation bioelectronic tattoos that are both therapeutic and aesthetically personalized.
文摘Objective： By applying moxibustion to the eight confluent points in different periods of time, to observe the changes in thermal pain threshold latency of acupoints based on Fei Teng Ba Fa. Methods： A total of 468 healthy college student volunteers received moxibustion at the eight confluent points in three different periods of time, i.e. Chen （7：00-9：00）, Wu （11：00-13：00） and Xu （19：00-21：00）. The thermal pain threshold latency was adopted to measure the changes in pain threshold of the eight confluent points under different conditions （different periods of time, different genders, different acupoints and different states of the acupoints） based on Fei Teng Ba Fa. Results： Finally, thirty subjects dropped out and 438 subjects were included. The comparison of thermal pain threshold latencies of the eight confluent points in the same opening or closing state based on Fei Teng Ba Fa： latencies of the closing points and adjunct points were significantly different in different periods of time （P〈0.05）, the latencies of the males were significantly longer than those of the females （P〈0.05）; there was no significant difference in the latency between the left and right sides （P〉0.05）; in the female group, there was a significant difference in the latency between the lower-limb points and the upper-limb points （P〈0.05）. The comparison of thermal point threshold latencies of the eight confluent points in different opening or closing state： in the period of Wu （11：00-13：00）, the latencies of the opening points were significantly longer than those of the closing points and adjunct points （P〈0.05）; for men, their opening and closing points had significantly longer thermal pain threshold latencies than their adjunct points （P〈0.05）; despite the gender, the latencies of the upper limb opening and closing points were significantly longer than the latency of the adjunct points （P〈0.05）; in the female group, the latencies of the lower-limb opening points were significantly shorter than those of the lower-limb closing and adjunct points （P〈0.05）. Conclusion： Based on Fei Teng Ba Fa, the pain thresholds of the eight confluent points vary in different periods of time, gender, acupoint location and opening/closing state, which can be taken as the evidence of making time-based acu puncture-moxibustion prescriptions.
基金support from National Natural Science Foundation of China(No.52173059)China National Textile and Apparel Council Science and Technology Guidance Project(No.2020116)+1 种基金the Key Research and Development Program of Jiangsu Province(No.21KJA540002)the Open Project of Tianjin Key Laboratory of Optoelectronic Detection Technology and System(No.2023LOTDS011).
文摘Portable power is an effective solution to realize self-powered sensors for wearable devices,promoting future sustainable development.Membrane-based triboelectric nanogenerators(M-TENGs)have emerged as a promising technology for harvesting biomechanical energy from human motion owing to their advantages,such as simple structure,lightweight design,and efficient energy conversion.However,the poor durability,low adaptability,and un-washability of two-dimensional membrane materials have largely hindered their application in wearable electronics.In this study,we propose a sheath-core polyvinylidene fluoride(PVDF)/graphene(G)-carbon fiber(CF)yarn fabricated via conjugate electrospinning,comprising a commercial CF core and an electrospun graphene-doped PVDF sheath,which improves the fatigue resistance of electrospun nanofiber films under prolonged friction and keeps a high degree of freedom.The resulting electronic textile,woven with the large-scale electrospun PVDF/G-CF yarn,demonstrates a remarkable power density of 25.5 mW·m^(-2).The tight distribution of PVDF/G nanofibers on the textile surface ensures excellent softness,washability,and durability.Furthermore,the electrospun PVDF/G-CF textile exhibits significant potential in pressure sensing,self-powered operation,and motion detection,making it highly suitable for wearable electronics applications.
基金the the opening fund of Key Laboratory of Science and Technology on Silicon Devices,Chinese Academy of Sciences[KLSDTJJ2022-5]the National Key Research and Development Program of China[2020YFE0205304]+2 种基金Natural Science Foundation of Chongqing,China[cstc2021jcyj-msxmX1002]the Fundamental Research Funds for the Central Universities[AUGA5710051221]Heilongjiang Provincial Natural Science Foundation of China[YQ2022E024].
文摘Recently,the triboelectric nanogenerator(TENG)has been widely studied for the development of flexible and wearable electronics.Among the various methods for TENG modification,melting nearfield direct writing is a new method to fabricate solid-liquid TENG.Here,the electrospun PCL was introduced with traditional polymers to fabricate the compound solid triboelectric layer,and water,dimethicone and GaIn were chosen as the liquid triboelectric layers.In this paper,the solid substrate effect,temperature gradient effect,and the liquid substrate effect were compared in terms of TENGs.A free-standing model of TENG is employed in this paper,and the charge generated by the PCL-PI composite solid triboelectrical solid layer is more than 10 times higher than the pristine one,showing the high charge generating ability to melt near-field direct written microfibers.Furthermore,detailed investigation will be discussed how we can get a high the out-circuit voltage and short-circuit current.
基金the Program for Taishan Scholars of Shandong Province(No.ts20190965)the National Key Research and Development Program of China(2020YFF0304600)+2 种基金the Key Research Program of the Chinese Academy of Sciences(Grant No.XDPB24)the National Natural Science Foundation of China(Grant No.51905518)the Innovation Leading Talents Program of Qingdao(19-3-2-23-zhc)in China.
文摘Water-solid triboelectric nanogenerators(TENGs),as new energy collection devices,have attracted increasing attention in ocean energy harvesting and selfpowered sensing.Polyacrylic acid(PAA)coating,usually used on the surface of marine equipment,has the property of anti-aging and anti-wear but limits triboelectrical output when used with TENGs.In this paper,polyacrylic acid coating was modified with fluorinated polyacrylate resin(F-PAA)to increase its triboelectrical output,by 6 times,and also to increase its anti-corrosion property.In addition,the corrosion resistance property can be further enhanced by cathodic protection using the electrical output generated by the water-flow triboelectrical energy transfer process.Given their easy fabrication,water-flow energy harvesting,and corrosion resistance,PAA/F-PAA coating-based TENGs have promising applications in river and ocean energy collection and corrosion protection.
