为了适应工程中多通道振动数据的快速存储和准确查询。基于LabVIEW的TDMS(technical data management streaming)数据逻辑方式,设计实现了一套完整的某试车台振动数据存储查询虚拟仪器系统。该系统可以通过手动存储和报警自动触发存储...为了适应工程中多通道振动数据的快速存储和准确查询。基于LabVIEW的TDMS(technical data management streaming)数据逻辑方式,设计实现了一套完整的某试车台振动数据存储查询虚拟仪器系统。该系统可以通过手动存储和报警自动触发存储两种方式对多通道、多类型海量数据进行快速存储。同时,还具有对指定通道指定类型数据的准确查询、导出以及打印功能等。在某型号试车台背景下开发出来的这套性能和操控界面兼备的监测系统,对于类似工程实践具有一定的借鉴意义。展开更多
在LabVIEW中分别使用TDMS(Technical Data Management Streaming)文件和SQL Server数据库分析处理实验数据,比较两者的运行速度。对速度较慢的方法再进行算法改进,相对提高运算效率,最终分析速度差异的根本原因,这将有助于在LabVIEW的...在LabVIEW中分别使用TDMS(Technical Data Management Streaming)文件和SQL Server数据库分析处理实验数据,比较两者的运行速度。对速度较慢的方法再进行算法改进,相对提高运算效率,最终分析速度差异的根本原因,这将有助于在LabVIEW的各种应用中合理使用数据处理方式。展开更多
Mycophenolic acid(MPA),the active moiety of both mycophenolate mofetil(MMF)and enteric-coated mycophenolate sodium(EC-MPS),serves as a primary immunosuppressant for maintaining solid organ transplants.Therapeutic drug...Mycophenolic acid(MPA),the active moiety of both mycophenolate mofetil(MMF)and enteric-coated mycophenolate sodium(EC-MPS),serves as a primary immunosuppressant for maintaining solid organ transplants.Therapeutic drug monitoring(TDM)enhances treatment outcomes through tailored approaches.This study aimed to develop an evidence-based guideline for MPA TDM,facilitating its rational application in clinical settings.The guideline plan was drawn from the Institute of Medicine and World Health Organization(WHO)guidelines.Using the Delphi method,clinical questions and outcome indicators were generated.Systematic reviews,Grading of Recommendations Assessment,Development,and Evaluation(GRADE)evidence quality evaluations,expert opinions,and patient values guided evidence-based suggestions for the guideline.External reviews further refined the recommendations.The guideline for the TDM of MPA(IPGRP-2020CN099)consists of four sections and 16 recommendations encompassing target populations,monitoring strategies,dosage regimens,and influencing factors.High-risk populations,timing of TDM,area under the curve(AUC)versus trough concentration(C0),target concentration ranges,monitoring frequency,and analytical methods are addressed.Formulation-specific recommendations,initial dosage regimens,populations with unique considerations,pharmacokinetic-informed dosing,body weight factors,pharmacogenetics,and drug–drug interactions are covered.The evidence-based guideline offers a comprehensive recommendation for solid organ transplant recipients undergoing MPA therapy,promoting standardization of MPA TDM,and enhancing treatment efficacy and safety.展开更多
文摘为了适应工程中多通道振动数据的快速存储和准确查询。基于LabVIEW的TDMS(technical data management streaming)数据逻辑方式,设计实现了一套完整的某试车台振动数据存储查询虚拟仪器系统。该系统可以通过手动存储和报警自动触发存储两种方式对多通道、多类型海量数据进行快速存储。同时,还具有对指定通道指定类型数据的准确查询、导出以及打印功能等。在某型号试车台背景下开发出来的这套性能和操控界面兼备的监测系统,对于类似工程实践具有一定的借鉴意义。
文摘在LabVIEW中分别使用TDMS(Technical Data Management Streaming)文件和SQL Server数据库分析处理实验数据,比较两者的运行速度。对速度较慢的方法再进行算法改进,相对提高运算效率,最终分析速度差异的根本原因,这将有助于在LabVIEW的各种应用中合理使用数据处理方式。
基金supported by the National Natural Science Foundation of China(NSFC)(No.72304007)the Huatong Guokang Medical Research Fund(No.2023HT010)。
文摘Mycophenolic acid(MPA),the active moiety of both mycophenolate mofetil(MMF)and enteric-coated mycophenolate sodium(EC-MPS),serves as a primary immunosuppressant for maintaining solid organ transplants.Therapeutic drug monitoring(TDM)enhances treatment outcomes through tailored approaches.This study aimed to develop an evidence-based guideline for MPA TDM,facilitating its rational application in clinical settings.The guideline plan was drawn from the Institute of Medicine and World Health Organization(WHO)guidelines.Using the Delphi method,clinical questions and outcome indicators were generated.Systematic reviews,Grading of Recommendations Assessment,Development,and Evaluation(GRADE)evidence quality evaluations,expert opinions,and patient values guided evidence-based suggestions for the guideline.External reviews further refined the recommendations.The guideline for the TDM of MPA(IPGRP-2020CN099)consists of four sections and 16 recommendations encompassing target populations,monitoring strategies,dosage regimens,and influencing factors.High-risk populations,timing of TDM,area under the curve(AUC)versus trough concentration(C0),target concentration ranges,monitoring frequency,and analytical methods are addressed.Formulation-specific recommendations,initial dosage regimens,populations with unique considerations,pharmacokinetic-informed dosing,body weight factors,pharmacogenetics,and drug–drug interactions are covered.The evidence-based guideline offers a comprehensive recommendation for solid organ transplant recipients undergoing MPA therapy,promoting standardization of MPA TDM,and enhancing treatment efficacy and safety.
