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An Approximate Hotelling T<sup>2</sup>-Test for Heteroscedastic One-Way MANOVA
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作者 Jin-Ting Zhang 《Open Journal of Statistics》 2012年第1期1-11,共11页
In this paper, we consider the general linear hypothesis testing (GLHT) problem in heteroscedastic one-way MANOVA. The well-known Wald-type test statistic is used. Its null distribution is approximated by a Hotelling ... In this paper, we consider the general linear hypothesis testing (GLHT) problem in heteroscedastic one-way MANOVA. The well-known Wald-type test statistic is used. Its null distribution is approximated by a Hotelling T2 distribution with one parameter estimated from the data, resulting in the so-called approximate Hotelling T2 (AHT) test. The AHT test is shown to be invariant under affine transformation, different choices of the contrast matrix specifying the same hypothesis, and different labeling schemes of the mean vectors. The AHT test can be simply conducted using the usual F-distribution. Simulation studies and real data applications show that the AHT test substantially outperforms the test of [1] and is comparable to the parametric bootstrap (PB) test of [2] for the multivariate k-sample Behrens-Fisher problem which is a special case of the GLHT problem in heteroscedastic one-way MANOVA. 展开更多
关键词 APPROXIMATE HOTELLING t2test MULTIVARIATE k-Sample Behrens-Fisher Problem Wishart-Approximation Wishart MIXTURE
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LOW FREQUENCY VARIABILITY OF INTERANNUAL CHANGE PATTERNS FOR GLOBAL MEAN TEMPERATURE DURING THE RECENT 100 YEARS
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作者 刘晶淼 丁裕国 余锦华 《Journal of Tropical Meteorology》 SCIE 2002年第1期46-55,共10页
The TEEOF method that expands temporally is used to conduct a diagnostic study of the variation patterns of 1, 3, 6 and 10 years with regard to mean air temperature over the globe and Southern and Northern Hemispheres... The TEEOF method that expands temporally is used to conduct a diagnostic study of the variation patterns of 1, 3, 6 and 10 years with regard to mean air temperature over the globe and Southern and Northern Hemispheres over the course of 100 years. The results show that the first mode of TEEOF takes up more than 50% in the total variance, with each of the first mode in the interannual oscillations generally standing for annually varying patterns which are related with climate and reflecting long-term tendency of change in air temperature. It is particularly true for the first mode on the 10-year scale, which shows an obvious ascending trend concerning the temperature in winter and consistently the primary component of time goes in a way that is very close to the sequence of actual temperature. Apart from the first mode of all time sections of TEEOF for the globe and the two hemispheres and the second mode of the 1-year TEEOF, interannual variation described by other characteristic vectors are showing various patterns, with corresponding primary components having relation with long-term variability of specific interannual quasi-periodic oscillation structures. A 2T test applied to the annual variation pattern shows that the abrupt changes for the Southern Hemisphere and the globe come closer to the result of a uni-element t test for mean temperature than those for the Northern Hemisphere do. It indicates that the 2Ttest, when carried out with patterns of multiple variables, seems more reasonable than the t test with single elements. 展开更多
关键词 global mean temperature patterns of interannual variation abrupt change of climate 2T test
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Optimal Estimation for Power of Variance with Application to Gene-Set Testing 被引量:1
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作者 Min XIAO Ting CHEN +1 位作者 Kunpeng HUANG Ruixing MING 《Journal of Systems Science and Information》 CSCD 2020年第6期549-564,共16页
Detecting differential expression of genes in genom research(e.g.,2019-nCoV)is not uncommon,due to the cost only small sample is employed to estimate a large number of variances(or their inverse)of variables simultane... Detecting differential expression of genes in genom research(e.g.,2019-nCoV)is not uncommon,due to the cost only small sample is employed to estimate a large number of variances(or their inverse)of variables simultaneously.However,the commonly used approaches perform unreliable.Borrowing information across different variables or priori information of variables,shrinkage estimation approaches are proposed and some optimal shrinkage estimators are obtained in the sense of asymptotic.In this paper,we focus on the setting of small sample and a likelihood-unbiased estimator for power of variances is given under the assumption that the variances are chi-squared distribution.Simulation reports show that the likelihood-unbiased estimators for variances and their inverse perform very well.In addition,application comparison and real data analysis indicate that the proposed estimator also works well. 展开更多
关键词 high-dimensional diagonal covariance matrix geometric shrinkage estimator small sample optimal shrinkage parameter likelihood-unbiased estimator hotelling’s t2test
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On the k-sample Behrens-Fisher problem for high-dimensional data 被引量:3
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作者 ZHANG JinTing XU JinFeng 《Science China Mathematics》 SCIE 2009年第6期1285-1304,共20页
For several decades, much attention has been paid to the two-sample Behrens-Fisher (BF) problem which tests the equality of the means or mean vectors of two normal populations with unequal variance/covariance structur... For several decades, much attention has been paid to the two-sample Behrens-Fisher (BF) problem which tests the equality of the means or mean vectors of two normal populations with unequal variance/covariance structures. Little work, however, has been done for the k-sample BF problem for high dimensional data which tests the equality of the mean vectors of several high-dimensional normal populations with unequal covariance structures. In this paper we study this challenging problem via extending the famous Scheffe’s transformation method, which reduces the k-sample BF problem to a one-sample problem. The induced one-sample problem can be easily tested by the classical Hotelling’s T 2 test when the size of the resulting sample is very large relative to its dimensionality. For high dimensional data, however, the dimensionality of the resulting sample is often very large, and even much larger than its sample size, which makes the classical Hotelling’s T 2 test not powerful or not even well defined. To overcome this difficulty, we propose and study an L 2-norm based test. The asymptotic powers of the proposed L 2-norm based test and Hotelling’s T 2 test are derived and theoretically compared. Methods for implementing the L 2-norm based test are described. Simulation studies are conducted to compare the L 2-norm based test and Hotelling’s T 2 test when the latter can be well defined, and to compare the proposed implementation methods for the L 2-norm based test otherwise. The methodologies are motivated and illustrated by a real data example. 展开更多
关键词 χ 2-approximation χ 2-type mixtures high-dimensional data analysis Hotelling’s T 2 test k-sample test L 2-norm based test Primary 62H15 Secondary 62E17 62E20
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具有遗传性疾病和性状的遗传位点分析 被引量:1
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作者 庞加平 黄姚宇翀 朱一琳 《数学的实践与认识》 北大核心 2017年第14期107-117,共11页
近年来,位点已成为人们研究DNA遗传信息的重要载体,其在疾病的性状和遗传机理的研究方面有重大帮助.主要结合遗传统计学中全基因组关联性分析(GWAS)、统计检验和机器学习等方法,通过对比分析样本人群的健康状况或疾病性状与位点编码来... 近年来,位点已成为人们研究DNA遗传信息的重要载体,其在疾病的性状和遗传机理的研究方面有重大帮助.主要结合遗传统计学中全基因组关联性分析(GWAS)、统计检验和机器学习等方法,通过对比分析样本人群的健康状况或疾病性状与位点编码来确定致病位点或致病基因的位置,并且通过受限制的波兹曼机(Restricted Boltzmann Machine,RBM)对一组疾病特征进行降维,从而能够结合统计检验方法特定该组疾病特征相应的致病位点. 展开更多
关键词 全基因组关联性分析 Hotelling-T2检验 Kruskal-Wallis检验 卡方齐性检验 受限制波兹曼机
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