In this study, we present the preparation of stable 1T-WS2 ultrathin nanosheets with NH~ intercalation using a bottom-up hydrothermal method and the potential application of this material in light-induced photothermal...In this study, we present the preparation of stable 1T-WS2 ultrathin nanosheets with NH~ intercalation using a bottom-up hydrothermal method and the potential application of this material in light-induced photothermal cancer therapy. Our results revealed that nanosheets with a size of 150 nm were highly hydrophilic and exhibited strong light absorption and excellent photostability in the broad near-infrared wavelength region. The in vitro experimental results indicated good biocompatibility of the nanosheets. More notably, our in vivo antitumor experiments illustrated that light-induced photothermal ablation originating from irradiation of the 1T-WS2 nanosheets with an 808 nm laser could efficiently kill tumor cells; these effects were obtained not only at the cellular level but also in the living organs of mice. This result may lead to new applications of two-dimensional layered materials in novel photothermal therapies and other photothermal related fields.展开更多
以条叶唇柱苣苔(Chirita ophiopogoides D Fang et W T Wang)的幼嫩叶片、种子为外植体,以MS为基本培养基,建立了条叶唇柱苣苔的组织培养和再生体系。试验结果表明:条叶唇柱苣苔叶片诱导不定芽的最佳培养基为MS+2,4-D0.5 mg/L+IAA 0.5 m...以条叶唇柱苣苔(Chirita ophiopogoides D Fang et W T Wang)的幼嫩叶片、种子为外植体,以MS为基本培养基,建立了条叶唇柱苣苔的组织培养和再生体系。试验结果表明:条叶唇柱苣苔叶片诱导不定芽的最佳培养基为MS+2,4-D0.5 mg/L+IAA 0.5 mg/L+NAA 0.2 mg/L,丛生芽分化的最佳培养基为MS+KT 1.0 mg/L+IAA 3.0 mg/L+NAA 0.5mg/L;MS+NAA 0.5 mg/L+6-BA 1.5 mg/L的培养基最适合继代,MS+IBA 2.0 mg/L+AC 0.5 mg/L培养基的生根效果最好,平均根长为4.67 cm,生根率达100%。展开更多
文摘In this study, we present the preparation of stable 1T-WS2 ultrathin nanosheets with NH~ intercalation using a bottom-up hydrothermal method and the potential application of this material in light-induced photothermal cancer therapy. Our results revealed that nanosheets with a size of 150 nm were highly hydrophilic and exhibited strong light absorption and excellent photostability in the broad near-infrared wavelength region. The in vitro experimental results indicated good biocompatibility of the nanosheets. More notably, our in vivo antitumor experiments illustrated that light-induced photothermal ablation originating from irradiation of the 1T-WS2 nanosheets with an 808 nm laser could efficiently kill tumor cells; these effects were obtained not only at the cellular level but also in the living organs of mice. This result may lead to new applications of two-dimensional layered materials in novel photothermal therapies and other photothermal related fields.
