提出T-球形模糊数的减法和除法算子,讨论T-球形模糊数减法和除法算子的性质。提出基于T-球形模糊减法和除法算子的灰色关联分析方法,并将该方法与多准则妥协解排序(vlsekriterijumska optimizacija i kompromisno resenje,VIKOR)方法结...提出T-球形模糊数的减法和除法算子,讨论T-球形模糊数减法和除法算子的性质。提出基于T-球形模糊减法和除法算子的灰色关联分析方法,并将该方法与多准则妥协解排序(vlsekriterijumska optimizacija i kompromisno resenje,VIKOR)方法结合,防止计算过程中T-球形模糊信息的丢失,利用一种新的得分函数完善T-球形模糊数的比较机制。通过实例及对比实验说明所提的基于T-球形模糊减法和除法算子的灰色-VIKOR方法的有效性和优越性,为解决T-球形模糊环境下的多属性决策问题提供新的有效的方法。展开更多
Pseudounipolar neurons in the dorsal root ganglia(DRG),as the central nodes of primary sensory afferents,possess a distinctive T-junction that is not merely a morphological peculiarity but also performs complex roles ...Pseudounipolar neurons in the dorsal root ganglia(DRG),as the central nodes of primary sensory afferents,possess a distinctive T-junction that is not merely a morphological peculiarity but also performs complex roles in rapid,multiplexed shunting and regulation of sensory signals.This specialized geometry enables separation,filtering,and feedback regulation of neuronal signals,thereby coordinating peripheral and central responses at multiple levels.Recent advances,including spatial transcriptomics,single-cell sequencing,super-resolution microscopy,organoid models,and novel electrophysiological methods,have permitted more precise dissection of the T-junction's molecular composition,ion-channel distribution,and electrophysiological properties.Here,we review current knowledge of the T-junction's developmental regulation and multilayered molecular networks,and we detail its functional alterations in both physiological signaling and pathological pain states,with particular emphasis on ion-channel modulation,signal attenuation,and selective transmission mechanisms.Finally,we discuss contemporary pain-intervention approaches and prospects for precision-targeted therapies,aiming to provide a theoretical foundation for future studies in pain physiology and clinical translation.展开更多
文摘提出T-球形模糊数的减法和除法算子,讨论T-球形模糊数减法和除法算子的性质。提出基于T-球形模糊减法和除法算子的灰色关联分析方法,并将该方法与多准则妥协解排序(vlsekriterijumska optimizacija i kompromisno resenje,VIKOR)方法结合,防止计算过程中T-球形模糊信息的丢失,利用一种新的得分函数完善T-球形模糊数的比较机制。通过实例及对比实验说明所提的基于T-球形模糊减法和除法算子的灰色-VIKOR方法的有效性和优越性,为解决T-球形模糊环境下的多属性决策问题提供新的有效的方法。
基金supported by grant from the National Key Technology Support Program of the Ministry of Science and Technology of China(No.2021ZD0203204)。
文摘Pseudounipolar neurons in the dorsal root ganglia(DRG),as the central nodes of primary sensory afferents,possess a distinctive T-junction that is not merely a morphological peculiarity but also performs complex roles in rapid,multiplexed shunting and regulation of sensory signals.This specialized geometry enables separation,filtering,and feedback regulation of neuronal signals,thereby coordinating peripheral and central responses at multiple levels.Recent advances,including spatial transcriptomics,single-cell sequencing,super-resolution microscopy,organoid models,and novel electrophysiological methods,have permitted more precise dissection of the T-junction's molecular composition,ion-channel distribution,and electrophysiological properties.Here,we review current knowledge of the T-junction's developmental regulation and multilayered molecular networks,and we detail its functional alterations in both physiological signaling and pathological pain states,with particular emphasis on ion-channel modulation,signal attenuation,and selective transmission mechanisms.Finally,we discuss contemporary pain-intervention approaches and prospects for precision-targeted therapies,aiming to provide a theoretical foundation for future studies in pain physiology and clinical translation.
