A hybrid method for synthesizing antenna＇s three dimensional （3D） pattern is proposed to obtain the low sidelobe feature of truncated cone conformal phased arrays. In this method, the elements of truncated cone con...A hybrid method for synthesizing antenna＇s three dimensional （3D） pattern is proposed to obtain the low sidelobe feature of truncated cone conformal phased arrays. In this method, the elements of truncated cone conformal phased arrays are projected to the tangent plane in one generatrix of the truncated cone. Then two dimensional （2D） Chebyshev amplitude distribution optimization is respectively used in two mutual vertical directions of the tangent plane. According to the location of the elements, the excitation current amplitude distribution of each element on the conformal structure is derived reversely, then the excitation current amplitude is further optimized by using the genetic algorithm （GA）. A truncated cone problem with 8x8 elements on it, and a 3D pattern desired side lobe level （SLL） up to 35 dB, is studied. By using the hybrid method, the optimal goal is accomplished with acceptable CPU time, which indicates that this hybrid method for the low sidelobe synthesis is feasible.展开更多
The reduction of disulfides by samarium diiodide led to sa arium thiolates (ArSSml2).This new thiolate anion species reacted smoothly with α, β -unsaturated esters (nitriles) to give 1,4-addition products β -thioes...The reduction of disulfides by samarium diiodide led to sa arium thiolates (ArSSml2).This new thiolate anion species reacted smoothly with α, β -unsaturated esters (nitriles) to give 1,4-addition products β -thioesters and β -thionitriles in good yields under mild and neutralcondition.展开更多
The crystal structure of the new title compound （E）-ethyl 6-benzyl-2-[（cyclopropylmethylamino）（4-fluorophenylamino）methyleneamino]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate ethanol monosolvate （C28H...The crystal structure of the new title compound （E）-ethyl 6-benzyl-2-[（cyclopropylmethylamino）（4-fluorophenylamino）methyleneamino]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate ethanol monosolvate （C28H31FN 4O2S·C2H6O, Mr=552.70） has been prepared and determined by single-crystal X-ray diffraction. The crystal is of monoclinic system, space group P21/c with a=13.806（10）, b=10.850（7）, c=19.938（14）, β=98.842（9）° , V=2951（4）3 , Z=4, Dc=1.244g/cm 3 , F（000）=1176, μ=0.153 mm-1 , MoKα radiation （λ=0.71073）, R=0.0758 and wR=0.2234 for 4262 observed reflections with I 〉 2σ（I）. Intramolecular N-H…S and C-H…N interactions as well as intermolecular N-H…O and O-H…N hydrogen bonds help to stabilize the crystal structure. X-ray diffraction analysis reveals that the asymmetric unit contains one title molecule and one ethanol molecule.展开更多
(3R,5R)-3-((tert-Butyldimethylsily)oxy)-5-((Z)-2-bromovinyl)-tetrahydro-furan-2-one, an intermediate for the synthesis of Fostriecin was achieved by intramolecular asymmetric induction in propene addition of (-)-8-phe...(3R,5R)-3-((tert-Butyldimethylsily)oxy)-5-((Z)-2-bromovinyl)-tetrahydro-furan-2-one, an intermediate for the synthesis of Fostriecin was achieved by intramolecular asymmetric induction in propene addition of (-)-8-phenylmenthyl glyoxylate followed by inversion of C3-hydroxyl group and Sharpless asymmetric dihydroxylation with simultaneous cyclization to give lactone 5. Then protection of C3-hydroxyl group and oxidation of the C6-primary hydroxyl group which reacted with Wittig reagent to yield the target compound 4.展开更多
A series of novel pyrazole-based lipoprotein-associated phospholipase A2 （Lp-PLA2） inhibitors have been de- signed and synthetized by a variety of acetophenones via a 10-step convergent approach. The synthetic appro...A series of novel pyrazole-based lipoprotein-associated phospholipase A2 （Lp-PLA2） inhibitors have been de- signed and synthetized by a variety of acetophenones via a 10-step convergent approach. The synthetic approach is carefully optimized, and an unsuccessful alternative route is also discussed. The in vitro biological activity reveals that all the synthesized compounds are potent Lp-PLA2 inhibitors with compound 13b being the most potent one （Lp-PLA2, IC50= 1.5 nmol/L）.展开更多
Poly（2-hydroxyethylmethacrylate） chains were grafted onto the backbone of agar using a microwave assisted method involving a combination of microwave irradiation and ceric ammonium nitrate to initiate the grafting r...Poly（2-hydroxyethylmethacrylate） chains were grafted onto the backbone of agar using a microwave assisted method involving a combination of microwave irradiation and ceric ammonium nitrate to initiate the grafting reaction. The synthesized graft copolymers were characterized by intrinsic viscosity measurements, Fourier transform infrared spectroscopy, elemental analysis （C, H, N, O and S） and scanning electron microscopy. Ag-g-P （HEMA）-2 showed a much higher flocculation efficacy than agar. The optimized dosage of flocculation for Ag-g-P （HEMA）-2 in the wastewater was found to be 0.75 ppm. Compared to agar, Ag-g-P（HEMA）-2 was found to considerably reduce the pollutant load in the wastewater.展开更多
New cycloaddition has been established for the synthesis of indoline-spiro benzofurodiazepine derivatives. Those reactions were conducted by reacting readily available and inexpensive starting materials, such as ben- ...New cycloaddition has been established for the synthesis of indoline-spiro benzofurodiazepine derivatives. Those reactions were conducted by reacting readily available and inexpensive starting materials, such as ben- zene- 1,2-diamines, tetronic acid and indoline-2,3-diones, in aqueous solution under microwave irradiation. When mono-substituted benzene-l,2-diamines as an amine component was employed, the reaction regioselectively re- sulted in the poly-functionalized indoline-spiro benzofurodiazepine with good yields. The present green synthesis shows attractive characteristics such as the use of water as reaction media, concise one-pot conditions, short reaction periods, easy work-up/purification and reduced waste production without the use of any strong acids or metal promoters.展开更多
Les anticorps semblent avoir une influence sur la reponse immunologique in vivo. Si Campbell a signale une stimulation de la synthese d’anticorps anti-albumine bovine (BSA) par l’injection de cet anticorps au cours ...Les anticorps semblent avoir une influence sur la reponse immunologique in vivo. Si Campbell a signale une stimulation de la synthese d’anticorps anti-albumine bovine (BSA) par l’injection de cet anticorps au cours de l’immunisation, Mason et al., Uhr et Baumann, Neiders et al., au contraire, ont montre que l’antitoxine et l’hemolysine elles-memes peuvent inhiber la formation de ces anticorps. Ces resultats contradictoires traduisent la complexite des experiences in vivo, car dans ces conditions, l’antigene co-展开更多
互联网信息技术与地理信息技术相结合的WebGIS技术已成为GIS发展的主流趋势之一,该文阐述了该主流技术的特点和相关技术,又以MapGuide软件作为主要支持技术,以SQL Sever 2000作为数据库管理工具,以校园信息数据为例,设计并实现了校园信...互联网信息技术与地理信息技术相结合的WebGIS技术已成为GIS发展的主流趋势之一,该文阐述了该主流技术的特点和相关技术,又以MapGuide软件作为主要支持技术,以SQL Sever 2000作为数据库管理工具,以校园信息数据为例,设计并实现了校园信息系统。实现了地图浏览、地图查询、要素编辑、三维实景浏览、数据信息的编辑等功能,为用户浏览校园信息提供了方便快捷的方式,亦可以在网页中浏览、方便管理地图信息。展开更多
基金supported by the Fundamental Research Funds for the Central Universities(YWF-13D2-XX-13)the National High-tech Research and Development Program(863 Program)(2008AA121802)
文摘A hybrid method for synthesizing antenna＇s three dimensional （3D） pattern is proposed to obtain the low sidelobe feature of truncated cone conformal phased arrays. In this method, the elements of truncated cone conformal phased arrays are projected to the tangent plane in one generatrix of the truncated cone. Then two dimensional （2D） Chebyshev amplitude distribution optimization is respectively used in two mutual vertical directions of the tangent plane. According to the location of the elements, the excitation current amplitude distribution of each element on the conformal structure is derived reversely, then the excitation current amplitude is further optimized by using the genetic algorithm （GA）. A truncated cone problem with 8x8 elements on it, and a 3D pattern desired side lobe level （SLL） up to 35 dB, is studied. By using the hybrid method, the optimal goal is accomplished with acceptable CPU time, which indicates that this hybrid method for the low sidelobe synthesis is feasible.
文摘The reduction of disulfides by samarium diiodide led to sa arium thiolates (ArSSml2).This new thiolate anion species reacted smoothly with α, β -unsaturated esters (nitriles) to give 1,4-addition products β -thioesters and β -thionitriles in good yields under mild and neutralcondition.
基金Supported by the National Natural Science Foundation of China (No.21102084)the Key Project of Hubei Provincial Department of Education (No.D20091301)Doctoral Startup Foundation of China Three Gorges University (No.KJ2009B004)
文摘The crystal structure of the new title compound （E）-ethyl 6-benzyl-2-[（cyclopropylmethylamino）（4-fluorophenylamino）methyleneamino]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate ethanol monosolvate （C28H31FN 4O2S·C2H6O, Mr=552.70） has been prepared and determined by single-crystal X-ray diffraction. The crystal is of monoclinic system, space group P21/c with a=13.806（10）, b=10.850（7）, c=19.938（14）, β=98.842（9）° , V=2951（4）3 , Z=4, Dc=1.244g/cm 3 , F（000）=1176, μ=0.153 mm-1 , MoKα radiation （λ=0.71073）, R=0.0758 and wR=0.2234 for 4262 observed reflections with I 〉 2σ（I）. Intramolecular N-H…S and C-H…N interactions as well as intermolecular N-H…O and O-H…N hydrogen bonds help to stabilize the crystal structure. X-ray diffraction analysis reveals that the asymmetric unit contains one title molecule and one ethanol molecule.
文摘(3R,5R)-3-((tert-Butyldimethylsily)oxy)-5-((Z)-2-bromovinyl)-tetrahydro-furan-2-one, an intermediate for the synthesis of Fostriecin was achieved by intramolecular asymmetric induction in propene addition of (-)-8-phenylmenthyl glyoxylate followed by inversion of C3-hydroxyl group and Sharpless asymmetric dihydroxylation with simultaneous cyclization to give lactone 5. Then protection of C3-hydroxyl group and oxidation of the C6-primary hydroxyl group which reacted with Wittig reagent to yield the target compound 4.
文摘A series of novel pyrazole-based lipoprotein-associated phospholipase A2 （Lp-PLA2） inhibitors have been de- signed and synthetized by a variety of acetophenones via a 10-step convergent approach. The synthetic approach is carefully optimized, and an unsuccessful alternative route is also discussed. The in vitro biological activity reveals that all the synthesized compounds are potent Lp-PLA2 inhibitors with compound 13b being the most potent one （Lp-PLA2, IC50= 1.5 nmol/L）.
文摘Poly（2-hydroxyethylmethacrylate） chains were grafted onto the backbone of agar using a microwave assisted method involving a combination of microwave irradiation and ceric ammonium nitrate to initiate the grafting reaction. The synthesized graft copolymers were characterized by intrinsic viscosity measurements, Fourier transform infrared spectroscopy, elemental analysis （C, H, N, O and S） and scanning electron microscopy. Ag-g-P （HEMA）-2 showed a much higher flocculation efficacy than agar. The optimized dosage of flocculation for Ag-g-P （HEMA）-2 in the wastewater was found to be 0.75 ppm. Compared to agar, Ag-g-P（HEMA）-2 was found to considerably reduce the pollutant load in the wastewater.
基金Project supported by the National Natural Science Foundation of China （Nos. 21072163 and 21002083）, Science Foundation in Interdisciplinary Major Research Project of Xuzhou Normal University （No. 09XKXKOI）, Doctoral Research Foundation of Xuzhou Normal University （XZNU, No. 1 0XLR20） and Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials （Nos. JSKC07035 and JSKC09062）.
文摘New cycloaddition has been established for the synthesis of indoline-spiro benzofurodiazepine derivatives. Those reactions were conducted by reacting readily available and inexpensive starting materials, such as ben- zene- 1,2-diamines, tetronic acid and indoline-2,3-diones, in aqueous solution under microwave irradiation. When mono-substituted benzene-l,2-diamines as an amine component was employed, the reaction regioselectively re- sulted in the poly-functionalized indoline-spiro benzofurodiazepine with good yields. The present green synthesis shows attractive characteristics such as the use of water as reaction media, concise one-pot conditions, short reaction periods, easy work-up/purification and reduced waste production without the use of any strong acids or metal promoters.
文摘Les anticorps semblent avoir une influence sur la reponse immunologique in vivo. Si Campbell a signale une stimulation de la synthese d’anticorps anti-albumine bovine (BSA) par l’injection de cet anticorps au cours de l’immunisation, Mason et al., Uhr et Baumann, Neiders et al., au contraire, ont montre que l’antitoxine et l’hemolysine elles-memes peuvent inhiber la formation de ces anticorps. Ces resultats contradictoires traduisent la complexite des experiences in vivo, car dans ces conditions, l’antigene co-
文摘互联网信息技术与地理信息技术相结合的WebGIS技术已成为GIS发展的主流趋势之一,该文阐述了该主流技术的特点和相关技术,又以MapGuide软件作为主要支持技术,以SQL Sever 2000作为数据库管理工具,以校园信息数据为例,设计并实现了校园信息系统。实现了地图浏览、地图查询、要素编辑、三维实景浏览、数据信息的编辑等功能,为用户浏览校园信息提供了方便快捷的方式,亦可以在网页中浏览、方便管理地图信息。
