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Green transplant:A scoping review of sustainability challenges and opportunities in transplantation
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作者 Angeliki Emmanouilidou Eleni Avramidou +3 位作者 Filippos F Karageorgos Nikolaos-Andreas Anastasopoulos Vassilios Papalois Georgios Tsoulfas 《World Journal of Transplantation》 2026年第1期63-74,共12页
Green transplant refers to the realization of the importance of understanding and improving the environmental footprint of transplantation through sustainable practices.This involves assessing the entire transplantati... Green transplant refers to the realization of the importance of understanding and improving the environmental footprint of transplantation through sustainable practices.This involves assessing the entire transplantation process including preoperative evaluation,donation,organ and patient transportation,surgery,postoperative recovery,and follow-up.This is a topic that has not been fully addressed yet,but its importance is being increasingly appreciated in surgery.The aim of this study was to investigate the carbon footprint associated with transplantation and propose sustainable mitigating solutions.A comprehensive review of the existing literature on transplantation was conducted and supplemented with findings from the broader fields of surgical and perioperative care,given the scarcity of available data.The analysis identified the most involved environmental factors and attempted to offer practical solutions based on current sustainability practices.Notably,no study has yet examined the carbon footprint associated with the entire transplantation procedure.Only five studies have attempted to assess the environmental impact of kidney or liver transplants,but they focused,almost explicitly,on specific steps of the process.By employing an extrapolative methodology from the broader surgical field,we determined that the primary contributors to the environmental impact of transplantation are energy,consumables and materials,anesthesia and pharmaceuticals,transportation,and water.This review offers practical solutions utilizing the 5R framework,emphasizing sustainability to ensure transplantation remains clinically and environmentally relevant. 展开更多
关键词 Green transplantation sustainability Environmental impact Carbon footprint REVIEW
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Evaluation and Forecasting of Water Sustainability in China Under Shared Socio-economic Pathways
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作者 SONG Song XIE Yufeng +2 位作者 WANG Zeyu YANG Jinxin YANG Zhiqi 《Chinese Geographical Science》 2025年第4期675-692,共18页
Water resources play a fundamental role in maintaining ecosystem well-being and supporting socio-economic progress.Nevertheless,the water sustainability confronts unprecedented challenges exacerbated by climate change... Water resources play a fundamental role in maintaining ecosystem well-being and supporting socio-economic progress.Nevertheless,the water sustainability confronts unprecedented challenges exacerbated by climate change and human interventions.This research establishes a comprehensive evaluation framework aligned with the United Nations'Sustainability Development Goals(SDGs)to assess water sustainability across 30 Chinese provinces,municipalities,and autonomous regions(excluding Xizang,Hong Kong,Macao and Taiwan).By integrating natural,economic,and social factors,this research elucidated the spatiotemporal evolution patterns of water sustainability from 2010 to 2020,and projected future trajectories under diverse socio-economic pathways(SSPs)for 2030 and 2050.The main findings include:1)China's water sustainability demonstrated gradual improvement during 2010–2020,yet baseline levels remain suboptimal for achieving SDG targets in 2030.Projections suggest significant enhancements by 2050,particularly under the SSP1-2.6 sustainability-oriented scenario.2)Persistent regional disparities are evident,with acute sustainability deficits observed in densely populated,intensively cultivated northern and the arid northwestern territories.These disparities are projected to attenuate by 2050.3)Natural ecological processes emerge as the dominant contributor to water sustainability,with projected growth potential.Economic processes constitute a secondary driver,while social dimensions exhibit more limited influence,both displaying heterogeneous developmental trajectories.4)SDG 6.4(Water Use Efficiency)demonstrates the highest implementation efficiency,whereas SDG 6.3(Water Quality)and SDG 15.1(Terrestrial Ecosystem Conservation)require urgent policy interventions.This study demonstrates the applicability of the proposed SDGs-aligned framework in diagnosing China's water sustainability challenges,providing actionable insights for regional policy prioritization.The interdisciplinary methodology bridges scientific analysis and governance strategies,enabling robust decision-making under complex future uncertainties. 展开更多
关键词 sustainability Development Goals(SDGs) water sustainability shared socio-economic pathways(SSPs) future projections China
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Smart Techniques Promoting Sustainability in Construction Engineering and Management 被引量:2
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作者 Song-Shun Lin Shui-Long Shen +1 位作者 Annan Zhou Xiang-Sheng Chen 《Engineering》 2025年第2期262-282,共21页
Construction engineering and management(CEM)has become increasingly complicated with the increasing size of engineering projects under different construction environments,motivating the digital transformation of CEM.T... Construction engineering and management(CEM)has become increasingly complicated with the increasing size of engineering projects under different construction environments,motivating the digital transformation of CEM.To contribute to a better understanding of the state of the art of smart techniques for engineering projects,this paper provides a comprehensive review of multi-criteria decision-making(MCDM)techniques,intelligent techniques,and their applications in CEM.First,a comprehensive framework detailing smart technologies for construction projects is developed.Next,the characteristics of CEM are summarized.A bibliometric review is then conducted to investigate the keywords,journals,and clusters related to the application of smart techniques in CEM during 2000-2022.Recent advancements in intelligent techniques are also discussed under the following six topics:①big data technology;②computer vision;③speech recognition;④natural language processing;⑤machine learning;and⑥knowledge representation,understanding,and reasoning.The applications of smart techniques are then illustrated via underground space exploitation.Finally,future research directions for the sustainable development of smart construction are highlighted. 展开更多
关键词 Construction engineering and management Multi-criteria decision-making techniques Intelligent techniques Digital transformation sustainability
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Optimizing the rotation cycle of previous crops increases crop yield and environmental sustainability in paddy field rotation 被引量:1
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作者 Siyu Gun Jing Liu +6 位作者 Fangyuan Huang Junwei Wang Hui Cheng Qigan Li Zhan Jiang Yonghua Zhu Ni Ma 《The Crop Journal》 2025年第4期1281-1290,共10页
Global food production faces enormous challenges in increasing yields while promoting environmental sustainability.A field experiments in the ecotone between the Yangtze River Basin and the HuangHuai-Hai Plain evaluat... Global food production faces enormous challenges in increasing yields while promoting environmental sustainability.A field experiments in the ecotone between the Yangtze River Basin and the HuangHuai-Hai Plain evaluated the effects of changing preceding crop rotation cycles(wheat and rapeseed)on long-term wheat-rice(W)and rapeseed-rice(R)rotation systems.A comprehensive evaluation of crop rotation systems was conducted using life cycle assessment,considering productivity,economic benefits,carbon footprint(CF),and soil health.Compared with fallow-rice rotation(F),alternating rapeseed and wheat rotations increased equivalent yield by 60.4%-82.2%,reduced CF by 0.3%-5.7%,and improved soil health by 0.3%-47.5%.Additionally,adding rapeseed to rotations increased soil nutrient content and raised soil organic carbon stocks by 31.3%-40.5%.The 3R rotation(3-year rapeseed-rice and 1-year wheat-rice)boosted rice yield by 82.2%and annual economic benefits by 84.4%,offering an effective model for optimizing long-term R rotations.Similarly,the 2W rotation(2-year wheat-rice and 1-year rapeseed rice)enhanced rice yield by 70.0% and annual economic benefits by 65.9%,providing a successful example for optimizing long-term W rotations.The 3R rapeseed-based rotation and the 2W wheatbased rotation demonstrated good environmental sustainability.These rotation systems have broad potential in sustainable intensive farming,especially in China and similar regions. 展开更多
关键词 Crop rotation RAPESEED Wheat Environmental sustainability Soil health
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Smart Grid Innovations: Increasing Resilience, Security, and Sustainability in the Era of Energy Transition 被引量:1
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作者 Yixin Yu Yanli Liu Didi Yu 《Engineering》 2025年第8期1-2,共2页
The accelerating global energy transition,driven by climate imperatives and technological advancements,demands fundamen-tal transformations in power systems.Smart grids,characterized by cyber-physical integration,dist... The accelerating global energy transition,driven by climate imperatives and technological advancements,demands fundamen-tal transformations in power systems.Smart grids,characterized by cyber-physical integration,distributed renewable resources,and data-driven intelligence,have emerged as the backbone of this evolution.This convergence,however,introduces unprecedented complexities in resilience,security,stability,and market operation.This special issue presents five pivotal studies addressing these interconnected challenges,offering novel methodologies and insights to advance the efficiency,resilience,and sustainability of modern power systems. 展开更多
关键词 SECURITY sustainability global energy transitiondriven smart grids RESILIENCE distributed renewable resources renewable resourcesand cyber physical integration
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Long-term combined application of organic and inorganic fertilizers increases crop yield sustainability by improving soil fertility in maize-wheat cropping systems 被引量:1
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作者 Jinfeng Wang Xueyun Yang +3 位作者 Shaomin Huang Lei Wu Zejiang Cai Minggang Xu 《Journal of Integrative Agriculture》 2025年第1期290-305,共16页
Organic material combined with inorganic fertilizer has been shown to greatly improve crop yield and maintain soil fertility globally. However, it remains unclear if crop yield and soil fertility can be sustained in t... Organic material combined with inorganic fertilizer has been shown to greatly improve crop yield and maintain soil fertility globally. However, it remains unclear if crop yield and soil fertility can be sustained in the long term under the combined application of organic and inorganic fertilizers. Three long-term field trials were conducted to investigate the effects of organic amendments on the grain sustainable yield index(SYI), soil fertility index(SFI)and nutrient balance in maize–wheat cropping systems of central and southern China during 1991–2019. Five treatments were included in the trials: 1) no fertilization(control);2) balanced mineral fertilization(NPK);3) NPK plus manure(NPKM);4) high dose of NPK plus manure(1.5NPKM);and 5) NPK plus crop straw(NPKS). Over time, the grain yields of wheat and maize showed an increasing trend in all four fertilization treatments at the Yangling(YL) and Zhengzhou(ZZ) locations, while they declined at Qiyang(QY). The grain yield in the NPKM and 1.5NPKM treatments gradually exceeded that of the NPK and NPKS treatments at the QY site. The largest SYI was recorded in the NPKM treatment across the three sites, suggesting that inorganic fertilizer combined with manure can effectively improve crop yield sustainability. Higher SYI values were recorded at the YL and ZZ sites than at the QY site, possibly because the soil was more acid at QY. The key factors affecting grain yield were soil available phosphorus(AP) and available potassium(AK) at the YL and ZZ sites, and pH and AP at the QY site.All fertilization treatments resulted in soil N and P surpluses at the three sites, but soil K surpluses were recorded only at the QY site. The SFI was greater in the 1.5NPKM, NPKM and NPKS treatments than in the NPK treatment by 13.3–40.0 and 16.4–63.6% at the YL and ZZ sites, respectively, and was significantly higher in the NPKM and 1.5NPKM treatments than in the NPK and NPKS treatments at the QY site. A significant, positive linear relationship was found between SFI and crop yield, and SYI and nutrient balance, indicating that grain yield and its sustainability significantly increased with increasing soil fertility. The apparent N, P and K balances positively affected SFI.This study suggests that the appropriate amount of manure mixed with mineral NPK fertilizer is beneficial to the development of sustainable agriculture, which effectively increases the crop yield and yield sustainability by improving soil fertility. 展开更多
关键词 organic amendments crop yield yield sustainability soil fertility nutrient balance
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Resource sustainability application of lithium iron phosphate batteries via citric acid coupled recycling and regeneration 被引量:1
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作者 Xiang Li Gui-Dong Li +1 位作者 Ye Chen Meng-Kui Tian 《Rare Metals》 2025年第6期4226-4240,共15页
Lithium iron phosphate(LiFePO_(4),LFP)batteries have shown extensive adoption in power applications in recent years for their reliable safety,high theoretical capability and low cost.Nevertheless,the finite lifespan o... Lithium iron phosphate(LiFePO_(4),LFP)batteries have shown extensive adoption in power applications in recent years for their reliable safety,high theoretical capability and low cost.Nevertheless,the finite lifespan of these batteries necessitates the future processing of a significant number of spent LFP batteries,underscoring the urgent need for the development of both efficient and eco-friendly recycling methods.This study combines the advantages of wet leaching and direct regeneration methods,leveraging citric acid's multifaceted role to streamline the combined leaching and hydrothermal processes.Results indicate that citric acid efficiently leaches all elements from spent LFP batteries.Furthermore,through its unique structure,it enhances hydrothermal regeneration by stabilizing metal ions and controlling crystal growth,and also acts as a carbon source for the surface carbon coating of regenerated LFP(RLFP).The R-LFP shows outstanding electrochemical stability,achieving a discharge capacity of 155.1 mAh.g^(-1)at 0.1C,with a capacity retention rate of 93.2%after 300 cycles at 1C.Furthermore,economic and environmental analyses demonstrate this method's superior cost-effectiveness and sustainability.Therefore,the method proposed in this study is efficient,simple and avoids the complex process of element separation,innovatively using a single reagent to achieve closed-loop recycling of LFP batteries,providing a novel and effective solution for the resource sustainability application. 展开更多
关键词 Spent LiFePO_(4) batteries Battery regeneration Resource sustainability
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Sludge Management: Integrating the Principle of Circular Economy into the Concept of Sustainability
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作者 Ludovico Spinosa 《Journal of Environmental Science and Engineering(A)》 CAS 2025年第1期53-59,共7页
The development of sustainable sludge management systems requires looking at them with a new vision in which the concepts of SD(Sustainable Development)must integrate those of CE(Circular Economy),both concepts subjec... The development of sustainable sludge management systems requires looking at them with a new vision in which the concepts of SD(Sustainable Development)must integrate those of CE(Circular Economy),both concepts subject to the principles of TD(Thermodynamics),thus allowing the adoption of actions that are all the more effective the more complete the evaluation of the social dimension has been.This involves a new“Way of thinking”which sees the sludge system as the“Locomotive”of the entire wastewater/sludge treatment train and is developed through“Ways of acting”which includes both“Technical”actions to maximize recoveries of useful materials and/or or energy,and“Socio/Institutional”actions to overcome barriers linked to local cultures and traditions,also considering that the specific local context heavily influences the choices capable of satisfying the concepts of CE.It follows the need of issuing realistic and applicable regulations and overcoming social barriers,such as lack of infrastructure and/or qualified personnel,to achieve an effective integration of the concepts of CE with the more general ones of sustainability. 展开更多
关键词 Circular economy REGULATION sludge management STANDARDIZATION sustainability.
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Students' sustainability consciousness with the three dimensions of sustainability:Does the locus of control play a role?
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作者 Durdana OVAIS 《Regional Sustainability》 2023年第1期13-27,共15页
The persistent environmental problems and the growing difficulty to achieve sustainable development require a re-evaluation of person’ sustainable knowledge, attitude, and behaviour. To go to where we want to go, we ... The persistent environmental problems and the growing difficulty to achieve sustainable development require a re-evaluation of person’ sustainable knowledge, attitude, and behaviour. To go to where we want to go, we must first assess where we are now. The study investigated the level of sustainability consciousness of students in India, and sustainability consciousness was expressed in sustainability knowledge, attitude, and behaviour. Sustainability consciousness was further examined using the three dimensions, such as environment, society, and economy. By drawing the perception map of students and studying the role of the locus of control, the reasons why sustainability knowledge does not appear in sustainability behaviour were analyzed. Quantitative analysis was conducted for a sample of 205 students from higher educational institutions across central India(Madhya Pradesh) from January to March in 2022. The data were analyzed using the SPSS 26 and Smart Partial Least Square(PLS) 3.0. The research revealed that sustainability attitude impacts sustainability behaviour more than sustainability knowledge. The results showed that respondents’ sustainability knowledge is higher than their sustainability attitude and behaviour. Moreover, it was discovered that economic concerns can lead to sustainability behaviour. In order to study respondents’ behaviour regarding sustainability consciousness, the study divided respondents into two groups according to the locus of control: the internal and external locus of control. It was found that most respondents thought whatever happened around them was beyond their control. Further, the locus of control influenced sustainability behaviour in groups with the internal locus of control. The study helps to explain why sustainability knowledge and attitude cannot translate into sustainability behaviour and provides a basis for achieving sustainable development. The conclusions of this study are crucial for governments, educational institutions, and organizations that empower youth to change their behaviour. 展开更多
关键词 sustainability CONSCIOUSNESS sustainability knowledge sustainability attitude sustainability behaviour Locus of control Higher education
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In the Green Zone With shared goals in sustainability and innovation, China and Singapore are advancing partnerships that could redefine the future of the green economy
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作者 Chio Hock Lai Paul 《China Report ASEAN》 2025年第12期27-27,共1页
This article is based on a speech by Executive Vice President of Singapore China Association Chio Hock Lai Paul at the opening ceremony of the ASEAN-China(Beijing Municipal Administrative Center)Trade and Investment P... This article is based on a speech by Executive Vice President of Singapore China Association Chio Hock Lai Paul at the opening ceremony of the ASEAN-China(Beijing Municipal Administrative Center)Trade and Investment Promotion Conference.Minor edits have been made for clarity and readability. 展开更多
关键词 sustainability SINGAPORE partnerships investment ASEAN TRADE green economy China
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Social-ecological indicators and framework for assessing the sustainability of shrimp farming in coastal Bangladesh
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作者 Kazi Atiah TAIYEBI Natalie Ann Cooper WELDEN Md Sarwar HOSSAIN 《Regional Sustainability》 2025年第5期39-56,共18页
Shrimp farming is a major global aquaculture activity;however,its social and ecological impacts raise sustainability concerns.While previous research has focused on isolated social or environmental aspects of sustaina... Shrimp farming is a major global aquaculture activity;however,its social and ecological impacts raise sustainability concerns.While previous research has focused on isolated social or environmental aspects of sustainability in shrimp farming,integrated assessments of these factors using a social-ecological systems(SES)approach are rare.A framework for assessing the sustainability of shrimp farming-comprising a set of social and ecological indicators-is developed and conceptualized in this study for the first time,using an integrated,interdisciplinary,and empirical SES approach.We first identified key social and ecological indicators and developed a conceptual framework based on SES approach,then surveyed 90 shrimp farms across 3 coastal regions(including Satkhira,Bagerhat,and Cox’s Bazar districts)in Bangladesh.Nearly all farmers in Satkhira(97%)and all in Bagerhat(100%)expressed dissatisfaction with the decreasing pattern of shrimp production and profitability over the last decade.In contrast,nearly all respondents in Cox’s Bazar(97%)reported satisfaction with increasing shrimp production.Except in Cox’s Bazar,equity in labor payment remained a concern for the social sustainability of the shrimp farming system.The changing pattern of shrimp production and profitability,which does not ensure equity,poses a threat to the sustainability of shrimp farming.Most of the surveyed farmers recognized the mutual benefits of mangrove forests and shrimp farming(97%in Satkhira and 77%in Cox’s Bazar),which suggests potential for the development of policy on integrated mangrove-shrimp farming with community-based management.This research could help assess the sustainability of the shrimp farming system and contribute to achieving Sustainable Development Goals 2(zero hunger)and 8(decent work and economic growth).By examining existing practices and developing a novel framework,this study highlights informed decision-making and guides methodological discussion on assessing the sustainability of shrimp farming using the SES approach in coastal regions and different aquaculture systems worldwide. 展开更多
关键词 Shrimp farming Social-ecological systems(SES) sustainability Sustainable Development Goals(SDGs) Coastal Bangladesh
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Chinese spandex enterprise named finalist at ITMF Sustainability&Innovation Award 2025
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作者 Zhao Xinhua 《China Textile》 2025年第6期10-11,共2页
The winners of the ITMF Sustainability&Innovation Awards 2025 and the ITMF Start-up Awards 2025 presented their project at the ITMF&IAF Conference 2025 which was held from 24-25 October in Yogyakarta,Indonesia... The winners of the ITMF Sustainability&Innovation Awards 2025 and the ITMF Start-up Awards 2025 presented their project at the ITMF&IAF Conference 2025 which was held from 24-25 October in Yogyakarta,Indonesia and was co-hosted by Indonesia Textile Industry Association(API). 展开更多
关键词 SPANDEX textile industry conference ENTERPRISE sustainability Yogyakarta Indonesia INNOVATION
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Enhancing Organizational Sustainability through Green HRM:A Conceptual Review
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作者 Md.Abu Issa Gazi Md.Farijul Islam +3 位作者 Shamal Mia Md.Nurun Nabi Margia Yesmin Abdul Rahman bin S Senathirajah 《Journal of Environmental & Earth Sciences》 2025年第5期30-48,共19页
This study delves into Green Human Resource Management(GHRM)as well as its link with organizational sustainability.Through a review of literature,this research hopes to fathom the place of eco-sustainability in employ... This study delves into Green Human Resource Management(GHRM)as well as its link with organizational sustainability.Through a review of literature,this research hopes to fathom the place of eco-sustainability in employee involvement and enhancing environmental responsibility via Green HRM.The main aim of this study is to thoroughly examine the literature on GHRM and its contribution to improving organizational sustainability through employee engagement and diminished environmental impact.The PRISMA guidelines were utilized in this conceptual review in order to investigate the impact that Green HRM has on the sustainability of organizations.The results show that Green HRM is vital for organizational sustainability since it reduces their ecological footprint,raises employee morale,and improves reputation.Additionally,the study emphasizes the significance of including Green HRM practices into organizational strategies and operations so as to achieve long-term sustainability.Findings indicate that through implementing green HRM practices organizations can record increased employee engagement levels,reduced turnover rates and improved customer satisfaction.Moreover,there are lower costs associated with green human resource management practices because of less waste and a better image for the brand.Nonetheless,some challenges and constraints towards change have been observed in relation to the implementation of these practices by companies.This study therefore gives an overview of how green HRM enhances organizational sustainability,thereby urging firms to adopt sustainable HR practices for successful operations in the future.These findings are important for human resource professionals,policymakers,or organizations who want to embed sustainability into their business strategy. 展开更多
关键词 Green HRM sustainability Sustainable Development Organizations Developing Country
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The Birth of Sustainability and Its Development in fib
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作者 Koji Sakai 《Journal of Civil Engineering and Architecture》 2025年第3期120-129,共10页
The history of human being is a result of various activities to live.Humanity has lived with the nature which has enabled to sustain the lives.Humanity has gained great benefits by the use of nature and its alternatio... The history of human being is a result of various activities to live.Humanity has lived with the nature which has enabled to sustain the lives.Humanity has gained great benefits by the use of nature and its alternation.The comfortable environment development made the increase of population and the alternation of nature has extended.The past few hundred years can be said the era of fossil fuels.Surprisingly,it has caused the global warming.The construction sector is the industry in which the foundation for social and economic activities is created.It has been believed that a comfortable and safety life,production and use of environments will lead to happiness for humanity.However,we could not put a break on the development.Of course it is,the construction-related sectors that consume the most large natural resources and energy,and therefore emit the largest quantity of CO_(2).Fortunately,a concept in which we can deal with this situation was developed.It is sustainability concept.In this paper,firstly the concept“sustainability”which was born at the end of 20th century is reconfirmed.As the performance-based design has played a significant role in sustainability design,secondly the concept is explained based on the author’s paper and book.Thirdly the development of sustainability in fib is comprehensively discussed including sustainability-resilience dispute and ethics. 展开更多
关键词 CO_(2) ETHICS FIB performance-based design RESILIENCE sustainability
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A Belgian Diplomat’s Sustainability Odyssey in China
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作者 ZHANG HUI 《China Today》 2025年第5期67-69,共3页
Captivated by the enduring wisdom of traditional Chinese culture and the country’s modern transformation,Patrick Nijs,former Belgian ambassador to China,chose to take root in the country after retirement and bring hi... Captivated by the enduring wisdom of traditional Chinese culture and the country’s modern transformation,Patrick Nijs,former Belgian ambassador to China,chose to take root in the country after retirement and bring his visionary green dream to life. 展开更多
关键词 RETIREMENT green dream ODYSSEY traditional chinese culture sustainability modern transformation belgian diplomat
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ISPO Award 2025:Advancing innovation and sustainability in sports fashion
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作者 Zhao Xinhua 《China Textile》 2025年第6期27-29,共3页
ISPO stands as the premier global sports industry event-serving as a catalyst for inspiration,a hub for professional connections,and a strategic compass for the upcoming season's trends.It is driven by the mission... ISPO stands as the premier global sports industry event-serving as a catalyst for inspiration,a hub for professional connections,and a strategic compass for the upcoming season's trends.It is driven by the mission to ignite the power of sport within every individual,creating impact so profound and far-reaching that its benefits are shared by all.On November 30,2025,the ISPO Award Gathering at ISPO Munich celebrated the innovation stars of the year.Under the direction of Christina Rabel,the Gold Winners were chosen-the products that stand out in terms of innovation,design and market relevance. 展开更多
关键词 innovation sustainability ispo award ignite power sport sports fashion professional connections market relevance sport impact
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Clinical outcomes and drug sustainability after non-medical switch from ustekinumab originator to biosimilars in inflammatory bowel disease
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作者 Justin Kritzinger Ivanna Candel +6 位作者 Gynter Kotrri Huzaifa Nadeem Waqqas Afif Alain Bitton Gary Wild Talat Bessissow Peter Laszlo Lakatos 《World Journal of Gastroenterology》 2025年第48期116-125,共10页
BACKGROUND Biologic therapies have transformed the management of inflammatory bowel disease(IBD),yet their high cost poses substantial challenges for healthcare systems.Biosimilars offer a cost-effective alternative,w... BACKGROUND Biologic therapies have transformed the management of inflammatory bowel disease(IBD),yet their high cost poses substantial challenges for healthcare systems.Biosimilars offer a cost-effective alternative,with extensive evidence supporting the safety and efficacy of non-medical switching for infliximab and adalimumab.However,real-world data on ustekinumab biosimilars in IBD remain limited.Given increasing mandates for non-medical switches in Canada,evaluating clinical outcomes is critical to ensure patient safety and treatment sustainability.We hypothesized that switching from originator ustekinumab to a biosimilar would preserve clinical efficacy,safety,and drug persistence in patients with IBD.AIM To evaluate clinical efficacy,treatment persistence,biomarker activity,and adverse events in IBD patients who underwent non-medical biosimilar switching from the ustekinumab originator to a biosimilar.METHODS This was an observational study of consecutive IBD patients who underwent a biosimilar switch.Disease activity,biomarkers,drug sustainability,and adverse events were captured 8 weeks before the switch,at the time of switch(baseline),12 weeks,and 24 weeks after the switch.RESULTS Of 81 patients were included[85.2%had Crohn’s disease,the median age at inclusion:42 years(interquartile ranges:29-61)].Previous biological exposure was 82.7%and a dose optimization of the originator ustekinumab was performed in 63%before the switch.Drug sustainability at 12 weeks and 24 weeks of switch was 96.3%and 95%,regardless of disease type or phenotype.The discontinuation rate was 4.9%.There was no significant difference in the rates of clinical remission at week 8 before switch,baseline,week 12,and 24 after switch:87%,85.9%,84.3%,and 92.7%,P=not statistically significant.The biomarker activity was not significantly different for C-reactive protein,hemoglobin,albumin,and fecal calprotectin(P=not statistically significant).All patients who stopped therapy after the non-medical switch needed a dose optimisation of the originator ustekinumab and had previous biological therapy prior to starting the ustekinumab originator.CONCLUSION Despite prior biologic exposure and frequent dose escalation,switching to ustekinumab biosimilar showed stable efficacy,unchanged biomarkers,and high treatment persistence. 展开更多
关键词 BIOSIMILAR Inflammatory bowel disease USTEKINUMAB Efficacy Drug sustainability
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The Evolution and Environmental Prospects of Renewable Bioplastics:Types,Production Methods,and Sustainability
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作者 Farah Syazwani Shahar Thinesh Sharma Balakrishnan Mohamed Thariq Hameed Sultan 《Journal of Renewable Materials》 2025年第6期1071-1101,共31页
In this comprehensive review,the evolution and progress of bioplastics are examined,with an emphasis on their types,production methods,environmental impact,and biodegradability.In light of the increasing global effort... In this comprehensive review,the evolution and progress of bioplastics are examined,with an emphasis on their types,production methods,environmental impact,and biodegradability.In light of the increasing global efforts to address environmental degradation,bioplastics have emerged as a highly potential substitute for conventional petroleum-based plastics.This review classifies various categories of bioplastics,encompassing both biodegradable and bio-based variations,and assesses their environmental consequences using life cycle evaluations and biodegradability calculations.This paper analyzes the technological advancements that have enhanced the mechanical and thermal characteristics of bioplastics,hence increasing their feasibility for extensive commercial applications in diverse sectors.This review critically examines the possible uses of bioplastics in important industries including packaging,aerospace,and healthcare,emphasizing both achievements and current obstacles.In addition,the assessment addresses the economic and technical obstacles to expanding bioplastic manufacturing,namely concerns about cost,material efficiency,and waste disposal.Moreover,the article forecasts the future potential of bioplastics in furthering a sustainable circular economy and suggests methods to address existing constraints,such as improvements in recycling technology and the establishment of more economically efficient manufacturing methods.The findings are intended to educate policymakers,industry stakeholders,and researchers on the crucial contribution of bioplastics in attaining sustainability objectives and promoting innovation in the field of material science. 展开更多
关键词 BIOPLASTICS sustainability circular economy environmental impact technological innovations
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Enhancing wastewater treatment efficiency with stereoscopic hydrogel evaporators and renewable energy integration for sustainability
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作者 unxiao Wang Yue Tian +3 位作者 Yonghang Yu Liang Wang Guangmiao Qu Shengyang Yang 《Chinese Journal of Chemical Engineering》 2025年第4期38-46,共9页
Enhancing wastewater treatment efficiency through innovative technologies is paramount in addressing global environmental challenges.This study explores utilizing stereoscopic hydrogel evaporators combined with renewa... Enhancing wastewater treatment efficiency through innovative technologies is paramount in addressing global environmental challenges.This study explores utilizing stereoscopic hydrogel evaporators combined with renewable energy sources to optimize wastewater treatment processes.A cross-linked super absorbent polymer(SAP)hydrogel was synthesized using acrylic acid and 2-hydroxyethyl methacrylate monomers and integrated with a light-absorbing carbon membrane to form a solar-assisted evaporator(MSAP).The MSAP achieved a high evaporation rate of 3.08 kg m^(-2)·h^(-1)and a photothermal conversion efficiency of 94.27%.It demonstrated excellent removal efficiency for dye-polluted wastewater,significantly reducing concentrations of pollutants.The MSAP maintained high performance in outdoor conditions,showcasing its potential for real-world applications.This approach,incorporating both solar and wind energy,significantly boosts water evaporation rates and presents a promising,eco-friendly solution for sustainable wastewater treatment within the circular development framework. 展开更多
关键词 Stereoscopic hydrogel evaporator EVAPORATION Solar energy Waste water sustainability
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