AIM: To retrospectively analyze factors affecting the long-term survival of patients with pancreatic cancer who underwent pancreatic resection.METHODS: From January 2000 to December 2011,195 patients underwent pancrea...AIM: To retrospectively analyze factors affecting the long-term survival of patients with pancreatic cancer who underwent pancreatic resection.METHODS: From January 2000 to December 2011,195 patients underwent pancreatic resection in our hospital.The prognostic factors after pancreatic resection were analyzed in all 195 patients.After excluding the censored cases within an observational period,the clinicopathological characteristics of 20 patients who survived ≥ 5(n = 20) and < 5(n = 76) years were compared.For this comparison,we analyzed the patients who underwent surgery before June 2008 and were observed for more than 5 years.For statistical analyses,the log-rank test was used to compare the cumulative survival rates,and the χ2 and Mann-Whitney tests were used to compare the two groups.The CoxHazard model was used for a multivariate analysis,and P values less than 0.05 were considered significant.A multivariate analysis was conducted on the factors that were significant in the univariate analysis.RESULTS: The median survival for all patients was 27.1 months,and the 5-year actuarial survival rate was 34.5%.The median observational period was 595 d.With the univariate analysis,the UICC stage was significantly associated with survival time,and the CA19-9 ≤ 200 U/m L,DUPAN-2 ≤ 180 U/m L,t u m o r s i ze ≤ 2 0 m m,R 0 re s e c t i o n,a b s e n c e o f lymph node metastasis,absence of extrapancreatic neural invasion,and absence of portal invasion were favorable prognostic factors.The multivariate analysis showed that tumor size ≤ 20 mm(HR = 0.40; 95%CI: 0.17-0.83,P = 0.012) and negative surgical margins(R0 resection)(HR = 0.48; 95%CI: 0.30-0.77,P = 0.003) were independent favorable prognostic factors.Among the 96 patients,20 patients survived for 5 years or more,and 76 patients died within 5 years after operation.Comparison of the 20 5-year survivors with the 76 non-survivors showed that lower concentrations of DUPAN-2(79.5 vs 312.5 U/mL,P = 0.032),tumor size ≤ 20 mm(35% vs 8%,P = 0.008),R0 resection(95% vs 61%,P = 0.004),and absence of lymph nodemetastases(60% vs 18%,P = 0.036) were significantly associated with the 5-year survival.CONCLUSION: Negative surgical margins and a tumor size ≤ 20 mm were independent favorable prognostic factors.Histologically curative resection and early tumor detection are important factors in achieving long-term survival.展开更多
The new curriculum,new ideas and new requirements concerning English teaching have made the rural English teaching face unprecedented challenges. There are many problems contributing to the poor effect of rural Englis...The new curriculum,new ideas and new requirements concerning English teaching have made the rural English teaching face unprecedented challenges. There are many problems contributing to the poor effect of rural English teaching,such as outdated teaching equipment,unreasonable curriculum design,insufficient teaching staff,asymmetrical teaching content,family education and students' personal problems. Based on the Chinese General Social Survey data,it is found that in terms of English reading,English speaking or English writing,the current English level of China's rural residents is lagging behind. From the average,the reading level of rural residents is better than the speaking and writing level,but the paired T-test results show that there are no significant differences between them,suggesting that under the current system of rural English teaching,the English level of rural residents is constrained to a low level. To improve the rural English teaching in the future,it is necessary to pay close attention to the following aspects: stabilizing the investment in rural education; optimizing the English teaching content; converting the philosophy of education; increasing teacher training; establishing the new linkage system.展开更多
Objectives To investigate prevalence of blood lipid level among 1401 residents aged≥60 years in rong-gui community.Methods 1401 ones(579 males,822 females,(68.12±6.64)years Of total 1503 residents aged≥60 years...Objectives To investigate prevalence of blood lipid level among 1401 residents aged≥60 years in rong-gui community.Methods 1401 ones(579 males,822 females,(68.12±6.64)years Of total 1503 residents aged≥60 years in the 2 villages which were randomly exampled in rong-gui community were investigated.867 ones aged among 60-69 years(61.9%),430 ones aged among 70-79 years(30.7%),104 ones aged≥60 years(7.4%).Investigative items included age,sex,total cholesterol(TC),triglyceride(TG),body height,body weight,waist circumference(WC),hip circumference(HC),fasting plasma glucose(FG),blood pressure,history of past illness,body mass index(BMI),waist hip ratio(WHR),waist height ratio(WHtR).Results(l)Of total 1401 residents,Prevalence of hyperlipemia were 42.8%,female were signifleanfly higher than male(P【0.01),The difference among three age groups were not significant,the combined prevalence of hyperlipemia and borderline hyperlipemia was 80.1%.(2)The FG、BMI、SBP、DBP、WC、WHR、WHtR of residents with hyperlipemia were higher than ones with normal blood lipid level(P【0.01).(3)By Pearson correlation analysis,we found that hyperlipemia was obviously correlated with FG,BMI,WC,WHR,WHtR,SBP,DBP.Conclusions(1)Prevalence of hyperlipemia were 42.8%,female were signifleanfly higher than male.(2)hyperlipemia were obviously correlated with higher FG、BMI、WC、WHR、WHtR、SBP、DBP.展开更多
Objectives To investigate prevalence of overweight and obesity among residents aged 3≥60 years in ronggui community.Methods 1372 ones(570 males,802 females,68.03±6.62 years)Of total 1503 residents aged≥60 years...Objectives To investigate prevalence of overweight and obesity among residents aged 3≥60 years in ronggui community.Methods 1372 ones(570 males,802 females,68.03±6.62 years)Of total 1503 residents aged≥60 years in the 2 villages which were randomly exampled in rong-gui community were investigated.857 ones aged among 60-69 years(62.5%),416 ones aged among 70-79 years(30.3%),99 ones aged≥60 years(7.2%).Investigative items included age,sex,body height,body weight,waist circumference(WC),hip circumference(HC)、fasting plasma glucose(FG),total cholesterol(TC),triglyceride(TG),blood pressure,history of past illness,body mass index(BMI),waist hip ratio(WHR)and waist height ratio(WHtR).Results(1)Of total 1372 residents,the combined prevalence of overweight and obesity was 39.4%.Prevalence of overweight,obesity were 29.4%,10.0%respectively.Prevalence of overweight,obesity of male were 30.8%,6.0%,and female,28.5%,12.8%respectively.Prevalence of overweight,obesity of residents aged 60-69 years were 31.2%,11.3%,70-79 years were 27.0%,9.1%and≥80 years were 25.2%,2.0%respectively.The difference between male and female、among three age groups were not significant.(2)Of total 1372 residents,prevalence of central adiposity were 34.6%,male was 15.9%and female was 52.4%,female signifleanfly higher than male(P【0.01).(3)The FG^TG.SBP^DBP of residents with overweight、obesity or central adiposity were higher than residents with normal weight or WC(P【0.01).(4)By Pearson correlation analysis,we found that overweight、obesity and central adiposity were obviously correlated with FG、TG、SBP、DBP(P【0.01),were not correlated with TC(P】0.05).Conclusions(1)Of total 1372 residents,the combined preva-lence of overweight and obesity was 39.4%,prevalence of overweight,obesity were 29.4%,10.0%respectively,prevalence of central adiposity were 34.6%,female was 52.4%,female signifleanfly higher than male.(2)overweight.obesity and central adiposity were obviously correlated with FG,TG,SBP,DBP.展开更多
文摘AIM: To retrospectively analyze factors affecting the long-term survival of patients with pancreatic cancer who underwent pancreatic resection.METHODS: From January 2000 to December 2011,195 patients underwent pancreatic resection in our hospital.The prognostic factors after pancreatic resection were analyzed in all 195 patients.After excluding the censored cases within an observational period,the clinicopathological characteristics of 20 patients who survived ≥ 5(n = 20) and < 5(n = 76) years were compared.For this comparison,we analyzed the patients who underwent surgery before June 2008 and were observed for more than 5 years.For statistical analyses,the log-rank test was used to compare the cumulative survival rates,and the χ2 and Mann-Whitney tests were used to compare the two groups.The CoxHazard model was used for a multivariate analysis,and P values less than 0.05 were considered significant.A multivariate analysis was conducted on the factors that were significant in the univariate analysis.RESULTS: The median survival for all patients was 27.1 months,and the 5-year actuarial survival rate was 34.5%.The median observational period was 595 d.With the univariate analysis,the UICC stage was significantly associated with survival time,and the CA19-9 ≤ 200 U/m L,DUPAN-2 ≤ 180 U/m L,t u m o r s i ze ≤ 2 0 m m,R 0 re s e c t i o n,a b s e n c e o f lymph node metastasis,absence of extrapancreatic neural invasion,and absence of portal invasion were favorable prognostic factors.The multivariate analysis showed that tumor size ≤ 20 mm(HR = 0.40; 95%CI: 0.17-0.83,P = 0.012) and negative surgical margins(R0 resection)(HR = 0.48; 95%CI: 0.30-0.77,P = 0.003) were independent favorable prognostic factors.Among the 96 patients,20 patients survived for 5 years or more,and 76 patients died within 5 years after operation.Comparison of the 20 5-year survivors with the 76 non-survivors showed that lower concentrations of DUPAN-2(79.5 vs 312.5 U/mL,P = 0.032),tumor size ≤ 20 mm(35% vs 8%,P = 0.008),R0 resection(95% vs 61%,P = 0.004),and absence of lymph nodemetastases(60% vs 18%,P = 0.036) were significantly associated with the 5-year survival.CONCLUSION: Negative surgical margins and a tumor size ≤ 20 mm were independent favorable prognostic factors.Histologically curative resection and early tumor detection are important factors in achieving long-term survival.
文摘The new curriculum,new ideas and new requirements concerning English teaching have made the rural English teaching face unprecedented challenges. There are many problems contributing to the poor effect of rural English teaching,such as outdated teaching equipment,unreasonable curriculum design,insufficient teaching staff,asymmetrical teaching content,family education and students' personal problems. Based on the Chinese General Social Survey data,it is found that in terms of English reading,English speaking or English writing,the current English level of China's rural residents is lagging behind. From the average,the reading level of rural residents is better than the speaking and writing level,but the paired T-test results show that there are no significant differences between them,suggesting that under the current system of rural English teaching,the English level of rural residents is constrained to a low level. To improve the rural English teaching in the future,it is necessary to pay close attention to the following aspects: stabilizing the investment in rural education; optimizing the English teaching content; converting the philosophy of education; increasing teacher training; establishing the new linkage system.
文摘Objectives To investigate prevalence of blood lipid level among 1401 residents aged≥60 years in rong-gui community.Methods 1401 ones(579 males,822 females,(68.12±6.64)years Of total 1503 residents aged≥60 years in the 2 villages which were randomly exampled in rong-gui community were investigated.867 ones aged among 60-69 years(61.9%),430 ones aged among 70-79 years(30.7%),104 ones aged≥60 years(7.4%).Investigative items included age,sex,total cholesterol(TC),triglyceride(TG),body height,body weight,waist circumference(WC),hip circumference(HC),fasting plasma glucose(FG),blood pressure,history of past illness,body mass index(BMI),waist hip ratio(WHR),waist height ratio(WHtR).Results(l)Of total 1401 residents,Prevalence of hyperlipemia were 42.8%,female were signifleanfly higher than male(P【0.01),The difference among three age groups were not significant,the combined prevalence of hyperlipemia and borderline hyperlipemia was 80.1%.(2)The FG、BMI、SBP、DBP、WC、WHR、WHtR of residents with hyperlipemia were higher than ones with normal blood lipid level(P【0.01).(3)By Pearson correlation analysis,we found that hyperlipemia was obviously correlated with FG,BMI,WC,WHR,WHtR,SBP,DBP.Conclusions(1)Prevalence of hyperlipemia were 42.8%,female were signifleanfly higher than male.(2)hyperlipemia were obviously correlated with higher FG、BMI、WC、WHR、WHtR、SBP、DBP.
文摘Objectives To investigate prevalence of overweight and obesity among residents aged 3≥60 years in ronggui community.Methods 1372 ones(570 males,802 females,68.03±6.62 years)Of total 1503 residents aged≥60 years in the 2 villages which were randomly exampled in rong-gui community were investigated.857 ones aged among 60-69 years(62.5%),416 ones aged among 70-79 years(30.3%),99 ones aged≥60 years(7.2%).Investigative items included age,sex,body height,body weight,waist circumference(WC),hip circumference(HC)、fasting plasma glucose(FG),total cholesterol(TC),triglyceride(TG),blood pressure,history of past illness,body mass index(BMI),waist hip ratio(WHR)and waist height ratio(WHtR).Results(1)Of total 1372 residents,the combined prevalence of overweight and obesity was 39.4%.Prevalence of overweight,obesity were 29.4%,10.0%respectively.Prevalence of overweight,obesity of male were 30.8%,6.0%,and female,28.5%,12.8%respectively.Prevalence of overweight,obesity of residents aged 60-69 years were 31.2%,11.3%,70-79 years were 27.0%,9.1%and≥80 years were 25.2%,2.0%respectively.The difference between male and female、among three age groups were not significant.(2)Of total 1372 residents,prevalence of central adiposity were 34.6%,male was 15.9%and female was 52.4%,female signifleanfly higher than male(P【0.01).(3)The FG^TG.SBP^DBP of residents with overweight、obesity or central adiposity were higher than residents with normal weight or WC(P【0.01).(4)By Pearson correlation analysis,we found that overweight、obesity and central adiposity were obviously correlated with FG、TG、SBP、DBP(P【0.01),were not correlated with TC(P】0.05).Conclusions(1)Of total 1372 residents,the combined preva-lence of overweight and obesity was 39.4%,prevalence of overweight,obesity were 29.4%,10.0%respectively,prevalence of central adiposity were 34.6%,female was 52.4%,female signifleanfly higher than male.(2)overweight.obesity and central adiposity were obviously correlated with FG,TG,SBP,DBP.
