Temporal lobe epilepsy(TLE)is the most common form of focal epilepsy in adults,with approximately 30%of patients developing drug resistance and requiring surgical evaluation[1].Epilepsy surgery achieves seizure-freedo...Temporal lobe epilepsy(TLE)is the most common form of focal epilepsy in adults,with approximately 30%of patients developing drug resistance and requiring surgical evaluation[1].Epilepsy surgery achieves seizure-freedom in a substantial proportion of cases[2].However,complex presentations of TLE remain difficult to manage surgically due to incongruent or indeterminate presurgical findings,which complicate delineation of the epileptogenic zone(EZ)and increase the likelihood of treatment failure.展开更多
基金supported by the Beijing Municipal Science&Technology Commission(Z231100004823035)the Capital Medical University Cultivation Project(PYZ24128)CAAE Epilepsy Research Fund(CU-2024-010).
文摘Temporal lobe epilepsy(TLE)is the most common form of focal epilepsy in adults,with approximately 30%of patients developing drug resistance and requiring surgical evaluation[1].Epilepsy surgery achieves seizure-freedom in a substantial proportion of cases[2].However,complex presentations of TLE remain difficult to manage surgically due to incongruent or indeterminate presurgical findings,which complicate delineation of the epileptogenic zone(EZ)and increase the likelihood of treatment failure.