Objective: To evaluate the clinical value of serum tumor supplied group of factor (TSGF) in diagnosis of epithelial ovarian cancer. Methods: The serum TSGF was tested in 69 patients with epithelial ovarian cancer, 28...Objective: To evaluate the clinical value of serum tumor supplied group of factor (TSGF) in diagnosis of epithelial ovarian cancer. Methods: The serum TSGF was tested in 69 patients with epithelial ovarian cancer, 28 patients with benign ovarian lesion and 61 healthy women. The serum levels of vascular endothelial growth factor (VEGF) and CA125 were determined in patients with epithelial ovarian cancer and in those with benign ovarian lesion. The correlations of TSGF with VEGF and CA125 were investigated. Results: The serum level of TSGF in patients with epithelial ovarian cancer was obviously higher than in patients with benign ovarian lesion and in healthy women (P<0.01). The serum level of TSGF in patients with epithelial cancer was associated with stage and grade. TSGF was highest in stage III, followed by stage IV, and was lowest in stage I-II. The TSGF level was lower in well-differentiated tumors and was higher in poorly differentiated tumor. There were no significant difference among diagnostic value of TSGF, VEGF, and CA125 in differentiation between epithelial ovarian cancer and benign ovarian lesion (P>0.05). The serum level of TSGF and VEGF and CA125 in patients with epithelial ovarian cancer showed positive correlation (P<0.01, P<0.05, respectively). Conclusion: There is no marked difference in diagnostic value among TSGF, VEGF and CA125. TSGF has a certain value in diagnosis of epithelial ovarian cancer, and is helpful to distinguish epithelial ovarian cancer from benign ovarian lesion.展开更多
The Guddu Thermal Power Plant of WAPDA is a main fossil powerplant in Pakistan,among which unit 4 with 210 MW in capacity suppliedby China,went into operation in 1986.Two 110 MW boiler-turbine-generator units and one ...The Guddu Thermal Power Plant of WAPDA is a main fossil powerplant in Pakistan,among which unit 4 with 210 MW in capacity suppliedby China,went into operation in 1986.Two 110 MW boiler-turbine-generator units and one 9 MW gas turbine-generator unit of phase Ⅰ projectof the power plant,provided by Skoda Export Co.of Czechoslovakia,wereput into operation in 1974,while one 210 MW boiler-turbine-generatorunit of phase Ⅱ,provided by the Technical Export Corporation of theSoviet Union,was put into operation in 1980.For the phase Ⅲ,one 210 MW boiler-turbine-generator unit,Which展开更多
In the Third Pole(TP)region,there are about 100,000 km2of glaciers[1],distributed mainly in the Tibetan Plateau and its surroundings.Glacier melt-water from these glaciers not only feeds rivers,such as the Indus,Brahm...In the Third Pole(TP)region,there are about 100,000 km2of glaciers[1],distributed mainly in the Tibetan Plateau and its surroundings.Glacier melt-water from these glaciers not only feeds rivers,such as the Indus,Brahmaputra,Ganges,Yellow and Yangtze,which finally reach the seas,but also feeds the rivers,such as the Tarim River,Heihe River and a lot of other rivers,which finally reach the arid areas or deserts.The Asian Water Tower[2]is,therefore,proposed to characterize the significance of the glaciers and glacier melt water at all the river heads in the TP,which is important water resource both for regulating seasonal water demands in the arid areas or deserts and for sea level rising.In addition,they also change the water cycle at a large scale[3].展开更多
The China-ASEAN Free Trade Area(CAFTA)3.0Upgrade Protocol added a section on“Supply Chain Connectivity,”which emphasizes that all parties recognize the lessons learned from the COVID-19 pandemic and cooperate to enh...The China-ASEAN Free Trade Area(CAFTA)3.0Upgrade Protocol added a section on“Supply Chain Connectivity,”which emphasizes that all parties recognize the lessons learned from the COVID-19 pandemic and cooperate to enhance the resilience of the regional supply chain.This is an inevitable trend amid the current accelerated restructuring of the global supply chain,the complex and severe international economic and trade situation,and the impact on the regional industrial chain.It also represents a fundamental shift and consensus on the logic of supply chain cooperation between China and ASEAN countries—a transformation from“Efficiency First”to“Resilience First.”展开更多
Against a backdrop of rising global trade protectionism and accelerated restructuring of international industrial and supply chains,regional institutional cooperation is becoming a key force in stabilizing cross-borde...Against a backdrop of rising global trade protectionism and accelerated restructuring of international industrial and supply chains,regional institutional cooperation is becoming a key force in stabilizing cross-border trade and investment.The ASEAN region enjoys strong economic growth momentum with a distinct demographic advantage while China boasts a complete industrial system and manufacturing capacity.展开更多
In the past few decades,China's foreign trade,leveraging its comprehensive industrial system,resilient supply chain,and factor cost advantages,has steadily constructed a global division of labor pattern as the“wo...In the past few decades,China's foreign trade,leveraging its comprehensive industrial system,resilient supply chain,and factor cost advantages,has steadily constructed a global division of labor pattern as the“world's factory”.展开更多
This study is to evaluate the clinical value of serum tumor supplied group of factors (TSGF) in diagnosis of canine cancer. 145 dogs with malignant tumors,32 benign diseases,34 dogs with non-tumor diseases,and 6 healt...This study is to evaluate the clinical value of serum tumor supplied group of factors (TSGF) in diagnosis of canine cancer. 145 dogs with malignant tumors,32 benign diseases,34 dogs with non-tumor diseases,and 6 healthy dogs. Biochemical colorimetric assay were used to detect the serum TSGF level. Blood samples were collected at the time of initial diagnostic evaluation,before each chemotherapy session,and at follow-up visits. The serum TSGF level in dogs with malignant tumors,benign diseases,non-tumor diseases and healthy dog were 67. 3 ± 22. 1 U/mL,57. 3 ± 7. 58 U/mL,60. 2 ± 14. 2 U/mL and 54. 6 ± 3. 21 U/mL,the first group was statistically significant higher than the latter (P < 0. 05). 56. 6% malignant patients exceeded the upper limit of the normal reference range (61 U/mL). The samples were classified to groups according clinic stage. The TSGF level from malignant tumor groups were stage I 56. 8 ± 5. 93 U/mL. stage II 66. 7 ± 25. 7 U/mL,stage III 75. 6 ± 22. 7 U/mL and stage IV 73. 9 ± 29. 6 U/mL. Excluding stage I, the TSGF level of all stages are statistically significant higher than healthy group,respectively,the stage III was also statistically significant higher than stage I. Further follow-up study indicated that in entirely insect group,the TSGF level decreased after treatment and kept in low level. In the partly insect group,although the TSGF activity decreased in a short term after surgery,the TSGF level would increase again and kept in high level. From this fact we considered that TSGF level is expected to be a newly potential biomarker in screening neoplastic diseases in veterinary and a monitoring factor for predicting relapse.展开更多
The world economy is now in a period of indepth adjustment.The intensification of geopolitical conflicts,a rise of trade protectionism,and reconfiguration of global supply chains have prompted all countries to re-exam...The world economy is now in a period of indepth adjustment.The intensification of geopolitical conflicts,a rise of trade protectionism,and reconfiguration of global supply chains have prompted all countries to re-examine their openness to trade amid rising uncertainties.Against this backdrop,China’s continuing commitment to promoting higherlevel opening up and building the Hainan Free Trade Port(Hainan FTP)has distinct contemporary significance and strategic value.展开更多
Purpose-This study explores how managerial leadership and organizational innovation interact to enhance resilience and risk management in railway supply chains and how these capabilities contribute to sustained compet...Purpose-This study explores how managerial leadership and organizational innovation interact to enhance resilience and risk management in railway supply chains and how these capabilities contribute to sustained competitive advantage.It emphasizes the strategic importance of resilience in railway systems that face operational complexity,regulatory pressures and increasing exposure to systemic risks.Design/methodology/approach-A mixed-methods design was employed,integrating survey data from 186 railway organizations with six case studies involving railway operators,rolling stock manufacturers and supply chain partners across multiple regions.Constructs were measured using validated scales and hypothesized relationships were tested using Structural Equation Modeling(SEM).Case study interviews were analyzed thematically to provide contextual understanding of leadership practices and innovation strategies.Findings-The results confirm that transformational managerial leadership significantly predicts innovation adoption,which in turn strengthens resilience and risk management capabilities.Resilience emerged as a powerful driver of competitive advantage,reinforcing its role as a strategic capability rather than a reactive response to disruptions.Furthermore,innovation was shown to partially mediate the relationship between leadership and resilience,highlighting its function as the operational channel through which vision translates into capability.Originality/value-This study contributes to the literature by integrating the Resource-Based View(RBV)and Dynamic Capabilities(DC)framework into the context of railway supply chains.It is among the first to empirically validate the mediating role of innovation between leadership and resilience,offering both theoretical advancements and actionable strategies for building resilient and competitive railway systems.展开更多
The shift to the China-ASEAN Free Trade Area(CAFTA)3.0 version marked more than just a technical update to an existing trade agreement.It signaled a recalibration ofregional economic cooperation as global trade has in...The shift to the China-ASEAN Free Trade Area(CAFTA)3.0 version marked more than just a technical update to an existing trade agreement.It signaled a recalibration ofregional economic cooperation as global trade has increasingly become shaped by digitalization,sustainability concerns,and fragile supply chains.For Indonesia,Southeast Asia’s largest economy and one of its most demographically dynamic,CAFTA 3.0 offers a framework that could materially strengthen its long-term economic position,if navigated with care and intent.展开更多
Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development...Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development of mechanization,wide-row spacing substrate cultivation became an optimize mode of the greenhouse cucumber cultivation,aligning with the trend of intelligent agriculture.To determine the optimal nutrient solution supply amount(NS)and supply frequency(SF)for promoting the integrated growth of cucumber under wide-row spacing substrate cultivation,we explored the effects of substrate supply amount(SS),NS,and SF on cucumber yield,quality,and element utilization efficiency.A five-level quadratic orthogonal rotation combination design with three experimental factors(NS,SF,and SS)was implemented for 23 coupling treatments over three growing seasons,including spring(2022S and 2023S)and autumn(2022A).The technique for order preference by similarity to ideal solution(TOPSIS)combining weights based on game theory was applied to construct cucumber comprehensive growth evaluation model.Single and two experimental factors analyses revealed significant effects of single factors and the coupling of NS-SS,NS-SF and SS-SF on the integrated growth of cucumber for all three growing seasons.For the NS-SF-SS combination,the optimal parameters for comprehensive cucumber growth were determined as follows:levels of^(-1).68 for NS,-0.7 for SF,and^(-1).682 for SS in 2022A;-0.43 for NS,-0.06 for SF,and 0.34 for SS in 2022S;0.3 for NS,-0.02 for SF,and 0.04 for SS in 2023S.Furthermore,for SS ranges of 2.00-3.01,3.01-4.50,4.50-5.99,5.99-7.00(L·plant^(-1)),the corresponding NS and SF intervals maximizing cucumber integrated growth in spring were:0.28-0.30(L·plant^(-1))and 6(times·d^(-1)),0.26-0.30(L·plant^(-1))and 6(times·d^(-1)),0.25-0.30(L·plant^(-1))and 6(times·d^(-1)),0.23-0.30(L·plant^(-1))and 6(times·d^(-1)),respectively.With the same SS,the corresponding NS and SF intervals that maximized cucumber integrated growth in autumn were:0.10(L·plant^(-1))and 8(times·d^(-1)),0.18(L·plant^(-1))and 7(times·d^(-1)),0.30(L·plant^(-1))and 6(times·d^(-1)),0.49(L·plant^(-1))and 5(times·d^(-1)),respectively.The results provide a theoretical basis for solution management,and further in-depth research on cucumber cultivation.展开更多
International trade serves as a crucial pathway for enhancing global food security and equality amid severe food crises worldwide.Under globalization,economic development has profoundly influenced food trade,while dis...International trade serves as a crucial pathway for enhancing global food security and equality amid severe food crises worldwide.Under globalization,economic development has profoundly influenced food trade,while disparities in food purchasing power among different economic development groups have led to uneven food security outcomes.However,the varying contributions of international trade to food security across these groups remain to be quantitatively elucidated.This study categorized countries into four economic development groups—high,high-medium,medium-low,and low—and examined changes in their food security scores from 2010 to 2019.The cross-group contributions of international trade to food security across these groups were compared.The results revealed that the food security score of the high economic development group was 9.22 times higher than that of the low economic development group.From 2010 to 2019,the high economic development group exhibited a significant upward trend in food security scores,whereas the low economic development group showed a significant decline.Moreover,international trade contributed significantly to both cross-group and within-group food security in the high economic development group,while its contribution to the low economic development group remained negligible.These findings demonstrated that international trade has further widened the food security gap between the high and low economic development groups,and its limited contribution to the low economic development group has failed to reverse the declining trend in their food security scores.This study quantified the divergent impacts of international trade on food security across economic development groups,providing valuable insights for optimizing global food trade policies—particularly in addressing the food security challenges faced by low econominc development group.展开更多
To achieve the goals of sustainable development of the energy system and the construction of a lowcarbon society,this study proposes a multi-energy storage collaborative optimization strategy for industrial park that ...To achieve the goals of sustainable development of the energy system and the construction of a lowcarbon society,this study proposes a multi-energy storage collaborative optimization strategy for industrial park that integrates the laddered carbon trading mechanism with demand response.Firstly,a dual dimensional DR model is constructed based on the characteristics of load elasticity.The alternativeDRenables flexible substitution of energy loads through complementary conversion of electricity/heat/cold multi-energy sources,while the price DR relies on timeof-use electricity price signals to guide load spatiotemporal migration;Secondly,the LCT mechanism is introduced to achieve optimal carbon emission costs through a tiered carbon quota allocation mechanism.On this basis,an optimization decision model is established with the core objective of maximizing the annual net profit of the park.The objective function takes into account energy sales revenue,generator unit costs,and investment and operation costs of multiple types of energy storage facilities.Themodel constraint system covers three key dimensions:dynamic operation constraints of power generation units,including unit output limits,ramping capability,and minimum start-stop time;the physical boundary of an electric/hot/cold multi-energy storage system involves energy storage capacity and charge/discharge efficiency;The multi-energy network coupling balance equation ensures that the energy conversion and transmission process satisfies the law of conservation of energy.Using CPLEX mathematical programming solver for simulation verification,construct an energy storage capacity configuration decision process that includes LCT-DR synergistic effect.The research results show that compared with the traditional single energy storage configuration mode,this strategy effectively enhances the economic feasibility and engineering practicality of industrial park operation by coordinating demand side resource scheduling and finely controlling carbon costs,while maintaining stable system operation.Its methodological framework provides a technical path that combines theoretical rigor and practical operability for the low-carbon transformation of regional integrated energy systems.展开更多
Understanding the spatial mach between water purification service supply and demand is crucial for optimizing watershed management and strengthening nature-society linkages,particularly in ecologically critical areas ...Understanding the spatial mach between water purification service supply and demand is crucial for optimizing watershed management and strengthening nature-society linkages,particularly in ecologically critical areas such as the Three Gorges Reservoir Area(TGRA).This study quantified the spatiotemporal patterns of water purification supply and demand by assessing the actual and potential non-point source pollution,and compared their mismatch ratio in the TGRA.Meanwhile,supply-demand reachability indicator was used to identify the water purification supply-demand relationship.Results showed that the TGRA generally maintained a balanced supply and demand relationship for water purification.Spatial analysis revealed that the ecosystem service demand and reachability indicator peaked in regions with>1000 m and>25°.Water purification exhibited High-High in the central Yangtze River corridor and southwestern TGRA,whereas Low-Low in the northern and southern regions.Driving analysis indicated climate factors significantly enhanced both supply(0.41)and demand(0.54),whereas soil factors exerted negative impacts on both supply(−0.37)and demand(−0.23).Topographic and socioeconomic factors also showed adverse,albeit relatively minor,effects.Based on the observed spatial mismatches,we propose shifting water purification governance strategies from aggregate control towards spatially targeted coordination that explicitly addresses distinct supply-demand relationships across different zones.展开更多
Following a magnitude M 7.9 earthquake that struck near Mandalay,Myanmar in March 2025,this study investigates the seismic damage inflicted upon the city’s municipal water supply system.The analysis focuses on the fa...Following a magnitude M 7.9 earthquake that struck near Mandalay,Myanmar in March 2025,this study investigates the seismic damage inflicted upon the city’s municipal water supply system.The analysis focuses on the failure characteristics of water facilities and pipelines,examines cross-system cascading effects,and proposes corresponding recovery strategies.The main findings are as follows:(1)The damage to water plant facilities,concentrated in ancillary structures and connections due to insufficient seismic measures,demonstrated significant intensity-dependence.Increased seismic intensity not only aggravated structural damage but also compromised core treatment processes,leading to deteriorated water quality.(2)Within the same seismic intensity zone,high-density polyethylene(HDPE)pipes exhibited a significantly lower damage occurrence rate than ductile iron(DI)pipes,highlighting the material’s substantial influence on seismic performance.Moreover,a strong positive correlation was observed between the overall pipeline network damage and the seismic intensity.The average damage rate in IntensityⅨzones was 6.84 times that of IntensityⅧzones.(3)A cascading failure,initiated by a power outage,led to water supply disruption,loss of emergency response capability,and elevated secondary risks.This strongly coupled cross-system effect resulted in significant spatiotemporal propagation of disaster impacts.(4)The post-earthquake recovery adopted a phased strategy that prioritized critical facilities.Actions involved rapidly restoring the core supply zone with temporary points,reinstating the water plant’s power supply,and deploying targeted technologies for efficient pipeline repair.The outcomes of this study are expected to provide critical support and a valuable reference for developing earthquake-resilient urban water supply systems.展开更多
Electrochemical CO_(2) reduction reaction(CO_(2)RR) into valuable formate provides a strategy for carbon neutrality.Bismuth(Bi) catalysts,attributed to their appropriate energy barrier of OCHO*intermediate,have demons...Electrochemical CO_(2) reduction reaction(CO_(2)RR) into valuable formate provides a strategy for carbon neutrality.Bismuth(Bi) catalysts,attributed to their appropriate energy barrier of OCHO*intermediate,have demonstrated substantial potential for the advancement of electrocatalytic CO_(2) reduction to formate.However,due to the weak bonding of protons(H^(*)) of Bi,the available protonate of CO_(2) on Bi is insufficient,which limits the formation of OCHO^(*).Prediction by theoretical calculation,chlorine doping can effectively promote the dissociation of H_(2)O and thus achieve effective proton supply.We prepare chlorine-doped Bi(Cl-Bi) via an electrochemical conversion strategy for electroreduction of CO_(2) .An obvious improvement of faradaic efficiency(FE) of formate(96.7% at-0.95 V vs.RHE) can be achieved on Cl-Bi,higher than that of Bi(89.4%).Meanwhile,Cl-Bi has the highest formate production rate of 275 μmol h^(-1)cm^(-2)at-0.95 V vs.RHE,which is 1.2 times higher than that of Bi(224 μmol h^(-1)cm^(-2)).In situ characterizations and kinetic analysis reveal that chlorine doping promotes the activation of H_(2)O and supply sufficient protons to promote the protonation of CO_(2) to OCHO^(*),which is consistent with theoretical calculation.The study presents an effective strategy for rational design of highly efficient electrocatalysts to promote green chemical production.展开更多
A comprehensive assessment of grain supply,demand,and ecosystem service flows is essential for identifying grain movement pathways,ensuring regional grain security,and guiding sustainable management strategies.However...A comprehensive assessment of grain supply,demand,and ecosystem service flows is essential for identifying grain movement pathways,ensuring regional grain security,and guiding sustainable management strategies.However,current studies primarily focus on short-term grain provision services while neglecting the spatiotemporal variations in grain flows across different scales.This gap limits the identification of dynamic matching relationships and the formulation of optimization strategies for balancing grain flows.This study examined the spatiotemporal evolution of grain supply and demand in the Beijing-Tianjin-Hebei(BTH)region from 1980 to 2020.Using the Enhanced TwoStep Floating Catchment Area method,the grain provision ecosystem service flows were quantified,the changes in supply–demand matching under different grain flow scenarios were analyzed and the optimal distance threshold for grain flows was investigated.The results revealed that grain production follows a spatial distribution pattern characterized by high levels in the southeast and low levels in the northwest.A significant mismatch exists between supply and demand,and it shows a scale effect.Deficit areas are mainly concentrated in the northwest,while surplus areas are mainly located in the central and southern regions.As the spatial scale increases,the ecosystem service supply–demand ratio(SDR)classification becomes more clustered,while it exhibits greater spatial SDR heterogeneity at smaller scales.This study examined two distinct scenarios of grain provision ecosystem service flow dynamics based on 100 and 200 km distance thresholds.The flow increased significantly,from 2.17 to 11.81million tons in the first scenario and from 2.41 to 12.37 million tons in the second scenario over nearly 40 years,forming a spatial movement pattern from the central and southern regions to the surrounding areas.Large flows were mainly concentrated in the interior of urban centers,with significant outflows between cities such as Baoding,Shijiazhuang,Xingtai,and Hengshui.At the county scale,supply–demand matching patterns remained consistent between the grain flows in the two scenarios.Notably,incorporating grain flow dynamics significantly reduced the number of grain-deficit areas compared to scenarios without grain flow.In 2020,grain-deficit counties decreased by28.79 and 37.88%,and cities by 12.50 and 25.0%under the two scenarios,respectively.Furthermore,the distance threshold for achieving optimal supply and demand matching at the county scale was longer than at the city scale in both grain flow scenarios.This study provides valuable insights into the dynamic relationships and heterogeneous patterns of grain matching,and expands the research perspective on grain and ecosystem service flows across various spatiotemporal scales.展开更多
Objectives This study aimed to design and evaluate a detection system for the accidental dislodgement of head-and-neck medical supplies through hand position recognition and tracking in Intensive Care Unit(ICU)patient...Objectives This study aimed to design and evaluate a detection system for the accidental dislodgement of head-and-neck medical supplies through hand position recognition and tracking in Intensive Care Unit(ICU)patients.Methods We conducted a single-center,prospective,parallel-group feasibility randomized controlled trial.We recruited 80 participants using convenience sampling from the ICU of a hospital in Ningbo City,Zhejiang Province,between March 2025 and June 2025,and they were randomly assigned to either the control group(routine care)or the intervention group(routine care plus image recognition-based detection system).The system continuously tracked patients’hand positions via bedside cameras and generated real-time alarms when hands entered predefined risk zones,notifying on-duty nurses to enable early intervention.System stability was assessed by continuous system uptime;system performance and clinical feasibility were evaluated by the frequencies of risk actions and accidental dislodgement of medical supplies(ADMS).Results All 80 participants completed the intervention,with 40 patients in each group.The baseline characteristics and median observation time of the two groups were balanced(intervention group:48 h/patient vs.control group:49 h/patient).Compared with the control group,the intervention group showed fewer ADMS(2/40 vs.9/40)and detected more risk actions per 100 h(36 vs.25);all system-detected events had corroborating images with complete concordance on manual review,and all nurse-recorded hand-contact events were accurately captured.Conclusions The study demonstrated that the image recognition-based detection system can function stably in clinical settings,providing accurate and continuous surveillance while supporting the early detection of risk actions.By reducing the observation burden and offering real-time cognitive support,the system complements routine nursing care and serves as an additional safety measure in ICU practice.With further optimization and larger multicenter validation,this approach could have the potential to make a significant contribution to the development of smart ICUs and the broader digital transformation of nursing care.展开更多
Ensuring reliable power supply in urban distribution networks is a complex and critical task.To address the increased demand during extreme scenarios,this paper proposes an optimal dispatch strategy that considers the...Ensuring reliable power supply in urban distribution networks is a complex and critical task.To address the increased demand during extreme scenarios,this paper proposes an optimal dispatch strategy that considers the coordination with virtual power plants(VPPs).The proposed strategy improves systemflexibility and responsiveness by optimizing the power adjustment of flexible resources.In the proposed strategy,theGaussian Process Regression(GPR)is firstly employed to determine the adjustable range of aggregated power within the VPP,facilitating an assessment of its potential contribution to power supply support.Then,an optimal dispatch model based on a leader-follower game is developed to maximize the benefits of the VPP and flexible resources while guaranteeing the power balance at the same time.To solve the proposed optimal dispatch model efficiently,the constraints of the problem are reformulated and resolved using the Karush-Kuhn-Tucker(KKT)optimality conditions and linear programming duality theorem.The effectiveness of the strategy is illustrated through a detailed case study.展开更多
The 15th Five-Year Plan will begin in 2026,amid heightened global technological competition and rapid supply chain changes.At this pivotal moment,the low-altitude economy and commercial aerospace,once seen as futurist...The 15th Five-Year Plan will begin in 2026,amid heightened global technological competition and rapid supply chain changes.At this pivotal moment,the low-altitude economy and commercial aerospace,once seen as futuristic,are quickly transitioning from strategic concepts to large-scale manufacturing industries.These sectors now drive China’s high-quality development and support a new framework for international engagement.展开更多
文摘Objective: To evaluate the clinical value of serum tumor supplied group of factor (TSGF) in diagnosis of epithelial ovarian cancer. Methods: The serum TSGF was tested in 69 patients with epithelial ovarian cancer, 28 patients with benign ovarian lesion and 61 healthy women. The serum levels of vascular endothelial growth factor (VEGF) and CA125 were determined in patients with epithelial ovarian cancer and in those with benign ovarian lesion. The correlations of TSGF with VEGF and CA125 were investigated. Results: The serum level of TSGF in patients with epithelial ovarian cancer was obviously higher than in patients with benign ovarian lesion and in healthy women (P<0.01). The serum level of TSGF in patients with epithelial cancer was associated with stage and grade. TSGF was highest in stage III, followed by stage IV, and was lowest in stage I-II. The TSGF level was lower in well-differentiated tumors and was higher in poorly differentiated tumor. There were no significant difference among diagnostic value of TSGF, VEGF, and CA125 in differentiation between epithelial ovarian cancer and benign ovarian lesion (P>0.05). The serum level of TSGF and VEGF and CA125 in patients with epithelial ovarian cancer showed positive correlation (P<0.01, P<0.05, respectively). Conclusion: There is no marked difference in diagnostic value among TSGF, VEGF and CA125. TSGF has a certain value in diagnosis of epithelial ovarian cancer, and is helpful to distinguish epithelial ovarian cancer from benign ovarian lesion.
文摘The Guddu Thermal Power Plant of WAPDA is a main fossil powerplant in Pakistan,among which unit 4 with 210 MW in capacity suppliedby China,went into operation in 1986.Two 110 MW boiler-turbine-generator units and one 9 MW gas turbine-generator unit of phase Ⅰ projectof the power plant,provided by Skoda Export Co.of Czechoslovakia,wereput into operation in 1974,while one 210 MW boiler-turbine-generatorunit of phase Ⅱ,provided by the Technical Export Corporation of theSoviet Union,was put into operation in 1980.For the phase Ⅲ,one 210 MW boiler-turbine-generator unit,Which
基金supported by the International Partnership Program of Chinese Academy of Sciences(131C11KYSB20160061)the Strategic Priority Research Program of Chinese Academy of Sciences(XDA20100309)
文摘In the Third Pole(TP)region,there are about 100,000 km2of glaciers[1],distributed mainly in the Tibetan Plateau and its surroundings.Glacier melt-water from these glaciers not only feeds rivers,such as the Indus,Brahmaputra,Ganges,Yellow and Yangtze,which finally reach the seas,but also feeds the rivers,such as the Tarim River,Heihe River and a lot of other rivers,which finally reach the arid areas or deserts.The Asian Water Tower[2]is,therefore,proposed to characterize the significance of the glaciers and glacier melt water at all the river heads in the TP,which is important water resource both for regulating seasonal water demands in the arid areas or deserts and for sea level rising.In addition,they also change the water cycle at a large scale[3].
文摘The China-ASEAN Free Trade Area(CAFTA)3.0Upgrade Protocol added a section on“Supply Chain Connectivity,”which emphasizes that all parties recognize the lessons learned from the COVID-19 pandemic and cooperate to enhance the resilience of the regional supply chain.This is an inevitable trend amid the current accelerated restructuring of the global supply chain,the complex and severe international economic and trade situation,and the impact on the regional industrial chain.It also represents a fundamental shift and consensus on the logic of supply chain cooperation between China and ASEAN countries—a transformation from“Efficiency First”to“Resilience First.”
文摘Against a backdrop of rising global trade protectionism and accelerated restructuring of international industrial and supply chains,regional institutional cooperation is becoming a key force in stabilizing cross-border trade and investment.The ASEAN region enjoys strong economic growth momentum with a distinct demographic advantage while China boasts a complete industrial system and manufacturing capacity.
文摘In the past few decades,China's foreign trade,leveraging its comprehensive industrial system,resilient supply chain,and factor cost advantages,has steadily constructed a global division of labor pattern as the“world's factory”.
文摘This study is to evaluate the clinical value of serum tumor supplied group of factors (TSGF) in diagnosis of canine cancer. 145 dogs with malignant tumors,32 benign diseases,34 dogs with non-tumor diseases,and 6 healthy dogs. Biochemical colorimetric assay were used to detect the serum TSGF level. Blood samples were collected at the time of initial diagnostic evaluation,before each chemotherapy session,and at follow-up visits. The serum TSGF level in dogs with malignant tumors,benign diseases,non-tumor diseases and healthy dog were 67. 3 ± 22. 1 U/mL,57. 3 ± 7. 58 U/mL,60. 2 ± 14. 2 U/mL and 54. 6 ± 3. 21 U/mL,the first group was statistically significant higher than the latter (P < 0. 05). 56. 6% malignant patients exceeded the upper limit of the normal reference range (61 U/mL). The samples were classified to groups according clinic stage. The TSGF level from malignant tumor groups were stage I 56. 8 ± 5. 93 U/mL. stage II 66. 7 ± 25. 7 U/mL,stage III 75. 6 ± 22. 7 U/mL and stage IV 73. 9 ± 29. 6 U/mL. Excluding stage I, the TSGF level of all stages are statistically significant higher than healthy group,respectively,the stage III was also statistically significant higher than stage I. Further follow-up study indicated that in entirely insect group,the TSGF level decreased after treatment and kept in low level. In the partly insect group,although the TSGF activity decreased in a short term after surgery,the TSGF level would increase again and kept in high level. From this fact we considered that TSGF level is expected to be a newly potential biomarker in screening neoplastic diseases in veterinary and a monitoring factor for predicting relapse.
文摘The world economy is now in a period of indepth adjustment.The intensification of geopolitical conflicts,a rise of trade protectionism,and reconfiguration of global supply chains have prompted all countries to re-examine their openness to trade amid rising uncertainties.Against this backdrop,China’s continuing commitment to promoting higherlevel opening up and building the Hainan Free Trade Port(Hainan FTP)has distinct contemporary significance and strategic value.
文摘Purpose-This study explores how managerial leadership and organizational innovation interact to enhance resilience and risk management in railway supply chains and how these capabilities contribute to sustained competitive advantage.It emphasizes the strategic importance of resilience in railway systems that face operational complexity,regulatory pressures and increasing exposure to systemic risks.Design/methodology/approach-A mixed-methods design was employed,integrating survey data from 186 railway organizations with six case studies involving railway operators,rolling stock manufacturers and supply chain partners across multiple regions.Constructs were measured using validated scales and hypothesized relationships were tested using Structural Equation Modeling(SEM).Case study interviews were analyzed thematically to provide contextual understanding of leadership practices and innovation strategies.Findings-The results confirm that transformational managerial leadership significantly predicts innovation adoption,which in turn strengthens resilience and risk management capabilities.Resilience emerged as a powerful driver of competitive advantage,reinforcing its role as a strategic capability rather than a reactive response to disruptions.Furthermore,innovation was shown to partially mediate the relationship between leadership and resilience,highlighting its function as the operational channel through which vision translates into capability.Originality/value-This study contributes to the literature by integrating the Resource-Based View(RBV)and Dynamic Capabilities(DC)framework into the context of railway supply chains.It is among the first to empirically validate the mediating role of innovation between leadership and resilience,offering both theoretical advancements and actionable strategies for building resilient and competitive railway systems.
文摘The shift to the China-ASEAN Free Trade Area(CAFTA)3.0 version marked more than just a technical update to an existing trade agreement.It signaled a recalibration ofregional economic cooperation as global trade has increasingly become shaped by digitalization,sustainability concerns,and fragile supply chains.For Indonesia,Southeast Asia’s largest economy and one of its most demographically dynamic,CAFTA 3.0 offers a framework that could materially strengthen its long-term economic position,if navigated with care and intent.
基金supported by the China Agriculture Research System(Grant No.CARS-23-D06)the Key Research and Development Program of Shaanxi Province(Grant Nos.2024NC2-GJHX-29 and 2024NC-ZDCYL-05-08)Shaanxi Agricultural Collaborative Innovation and Extension Alliance Project(Grant No.LMZD202202).
文摘Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development of mechanization,wide-row spacing substrate cultivation became an optimize mode of the greenhouse cucumber cultivation,aligning with the trend of intelligent agriculture.To determine the optimal nutrient solution supply amount(NS)and supply frequency(SF)for promoting the integrated growth of cucumber under wide-row spacing substrate cultivation,we explored the effects of substrate supply amount(SS),NS,and SF on cucumber yield,quality,and element utilization efficiency.A five-level quadratic orthogonal rotation combination design with three experimental factors(NS,SF,and SS)was implemented for 23 coupling treatments over three growing seasons,including spring(2022S and 2023S)and autumn(2022A).The technique for order preference by similarity to ideal solution(TOPSIS)combining weights based on game theory was applied to construct cucumber comprehensive growth evaluation model.Single and two experimental factors analyses revealed significant effects of single factors and the coupling of NS-SS,NS-SF and SS-SF on the integrated growth of cucumber for all three growing seasons.For the NS-SF-SS combination,the optimal parameters for comprehensive cucumber growth were determined as follows:levels of^(-1).68 for NS,-0.7 for SF,and^(-1).682 for SS in 2022A;-0.43 for NS,-0.06 for SF,and 0.34 for SS in 2022S;0.3 for NS,-0.02 for SF,and 0.04 for SS in 2023S.Furthermore,for SS ranges of 2.00-3.01,3.01-4.50,4.50-5.99,5.99-7.00(L·plant^(-1)),the corresponding NS and SF intervals maximizing cucumber integrated growth in spring were:0.28-0.30(L·plant^(-1))and 6(times·d^(-1)),0.26-0.30(L·plant^(-1))and 6(times·d^(-1)),0.25-0.30(L·plant^(-1))and 6(times·d^(-1)),0.23-0.30(L·plant^(-1))and 6(times·d^(-1)),respectively.With the same SS,the corresponding NS and SF intervals that maximized cucumber integrated growth in autumn were:0.10(L·plant^(-1))and 8(times·d^(-1)),0.18(L·plant^(-1))and 7(times·d^(-1)),0.30(L·plant^(-1))and 6(times·d^(-1)),0.49(L·plant^(-1))and 5(times·d^(-1)),respectively.The results provide a theoretical basis for solution management,and further in-depth research on cucumber cultivation.
基金supported by National Natural Science Foundation of China(Grants No.42361144888 and 42401308)National Key Research and Development Program of China(Grant No.2024YFF1309200).
文摘International trade serves as a crucial pathway for enhancing global food security and equality amid severe food crises worldwide.Under globalization,economic development has profoundly influenced food trade,while disparities in food purchasing power among different economic development groups have led to uneven food security outcomes.However,the varying contributions of international trade to food security across these groups remain to be quantitatively elucidated.This study categorized countries into four economic development groups—high,high-medium,medium-low,and low—and examined changes in their food security scores from 2010 to 2019.The cross-group contributions of international trade to food security across these groups were compared.The results revealed that the food security score of the high economic development group was 9.22 times higher than that of the low economic development group.From 2010 to 2019,the high economic development group exhibited a significant upward trend in food security scores,whereas the low economic development group showed a significant decline.Moreover,international trade contributed significantly to both cross-group and within-group food security in the high economic development group,while its contribution to the low economic development group remained negligible.These findings demonstrated that international trade has further widened the food security gap between the high and low economic development groups,and its limited contribution to the low economic development group has failed to reverse the declining trend in their food security scores.This study quantified the divergent impacts of international trade on food security across economic development groups,providing valuable insights for optimizing global food trade policies—particularly in addressing the food security challenges faced by low econominc development group.
基金funded by Science and Technology Projects from State Grid Corporation of China,(Research on Adaptive Balance Optimization and Simulation Technology of Industrial community Energy System with High Proportion of Distributed Energy,No.:5100-202355752A-3-4-SY).
文摘To achieve the goals of sustainable development of the energy system and the construction of a lowcarbon society,this study proposes a multi-energy storage collaborative optimization strategy for industrial park that integrates the laddered carbon trading mechanism with demand response.Firstly,a dual dimensional DR model is constructed based on the characteristics of load elasticity.The alternativeDRenables flexible substitution of energy loads through complementary conversion of electricity/heat/cold multi-energy sources,while the price DR relies on timeof-use electricity price signals to guide load spatiotemporal migration;Secondly,the LCT mechanism is introduced to achieve optimal carbon emission costs through a tiered carbon quota allocation mechanism.On this basis,an optimization decision model is established with the core objective of maximizing the annual net profit of the park.The objective function takes into account energy sales revenue,generator unit costs,and investment and operation costs of multiple types of energy storage facilities.Themodel constraint system covers three key dimensions:dynamic operation constraints of power generation units,including unit output limits,ramping capability,and minimum start-stop time;the physical boundary of an electric/hot/cold multi-energy storage system involves energy storage capacity and charge/discharge efficiency;The multi-energy network coupling balance equation ensures that the energy conversion and transmission process satisfies the law of conservation of energy.Using CPLEX mathematical programming solver for simulation verification,construct an energy storage capacity configuration decision process that includes LCT-DR synergistic effect.The research results show that compared with the traditional single energy storage configuration mode,this strategy effectively enhances the economic feasibility and engineering practicality of industrial park operation by coordinating demand side resource scheduling and finely controlling carbon costs,while maintaining stable system operation.Its methodological framework provides a technical path that combines theoretical rigor and practical operability for the low-carbon transformation of regional integrated energy systems.
基金sponsored by the National Natural Science Foundation of China(Grant number 42471510,42001218)National Major Water Conservancy Project Construction(follow up to the Three Gorges Project)(No.12620202700221 J001,NO.102126222020270029030)General Project of Hubei Social Science Fund(No.2021211,HBSK2022YB357,HBSKJJ20233269,HBSKJJ20243233).
文摘Understanding the spatial mach between water purification service supply and demand is crucial for optimizing watershed management and strengthening nature-society linkages,particularly in ecologically critical areas such as the Three Gorges Reservoir Area(TGRA).This study quantified the spatiotemporal patterns of water purification supply and demand by assessing the actual and potential non-point source pollution,and compared their mismatch ratio in the TGRA.Meanwhile,supply-demand reachability indicator was used to identify the water purification supply-demand relationship.Results showed that the TGRA generally maintained a balanced supply and demand relationship for water purification.Spatial analysis revealed that the ecosystem service demand and reachability indicator peaked in regions with>1000 m and>25°.Water purification exhibited High-High in the central Yangtze River corridor and southwestern TGRA,whereas Low-Low in the northern and southern regions.Driving analysis indicated climate factors significantly enhanced both supply(0.41)and demand(0.54),whereas soil factors exerted negative impacts on both supply(−0.37)and demand(−0.23).Topographic and socioeconomic factors also showed adverse,albeit relatively minor,effects.Based on the observed spatial mismatches,we propose shifting water purification governance strategies from aggregate control towards spatially targeted coordination that explicitly addresses distinct supply-demand relationships across different zones.
基金National Key Research and Development Program of China under Grant No.2023YFC3805201Scientific Research Fund of Institute of Engineering Mechanics,China Earthquake Administration under Grant Nos.2024B29 and 2024B25。
文摘Following a magnitude M 7.9 earthquake that struck near Mandalay,Myanmar in March 2025,this study investigates the seismic damage inflicted upon the city’s municipal water supply system.The analysis focuses on the failure characteristics of water facilities and pipelines,examines cross-system cascading effects,and proposes corresponding recovery strategies.The main findings are as follows:(1)The damage to water plant facilities,concentrated in ancillary structures and connections due to insufficient seismic measures,demonstrated significant intensity-dependence.Increased seismic intensity not only aggravated structural damage but also compromised core treatment processes,leading to deteriorated water quality.(2)Within the same seismic intensity zone,high-density polyethylene(HDPE)pipes exhibited a significantly lower damage occurrence rate than ductile iron(DI)pipes,highlighting the material’s substantial influence on seismic performance.Moreover,a strong positive correlation was observed between the overall pipeline network damage and the seismic intensity.The average damage rate in IntensityⅨzones was 6.84 times that of IntensityⅧzones.(3)A cascading failure,initiated by a power outage,led to water supply disruption,loss of emergency response capability,and elevated secondary risks.This strongly coupled cross-system effect resulted in significant spatiotemporal propagation of disaster impacts.(4)The post-earthquake recovery adopted a phased strategy that prioritized critical facilities.Actions involved rapidly restoring the core supply zone with temporary points,reinstating the water plant’s power supply,and deploying targeted technologies for efficient pipeline repair.The outcomes of this study are expected to provide critical support and a valuable reference for developing earthquake-resilient urban water supply systems.
基金financially supported by the Natural Science Foundation of Shandong Province (No.ZR2022QE076)the National Natural Science Foundation of China (No.52202092)the Science and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China (No.2023KJ104)。
文摘Electrochemical CO_(2) reduction reaction(CO_(2)RR) into valuable formate provides a strategy for carbon neutrality.Bismuth(Bi) catalysts,attributed to their appropriate energy barrier of OCHO*intermediate,have demonstrated substantial potential for the advancement of electrocatalytic CO_(2) reduction to formate.However,due to the weak bonding of protons(H^(*)) of Bi,the available protonate of CO_(2) on Bi is insufficient,which limits the formation of OCHO^(*).Prediction by theoretical calculation,chlorine doping can effectively promote the dissociation of H_(2)O and thus achieve effective proton supply.We prepare chlorine-doped Bi(Cl-Bi) via an electrochemical conversion strategy for electroreduction of CO_(2) .An obvious improvement of faradaic efficiency(FE) of formate(96.7% at-0.95 V vs.RHE) can be achieved on Cl-Bi,higher than that of Bi(89.4%).Meanwhile,Cl-Bi has the highest formate production rate of 275 μmol h^(-1)cm^(-2)at-0.95 V vs.RHE,which is 1.2 times higher than that of Bi(224 μmol h^(-1)cm^(-2)).In situ characterizations and kinetic analysis reveal that chlorine doping promotes the activation of H_(2)O and supply sufficient protons to promote the protonation of CO_(2) to OCHO^(*),which is consistent with theoretical calculation.The study presents an effective strategy for rational design of highly efficient electrocatalysts to promote green chemical production.
基金supported by the National Natural Science Foundation of China(42471336,52379021 and 42201278)the Hebei Province Backbone Talent Program,China(Returnee Platform for Overseas Study)(A20240028)+2 种基金the Hebei Province Statistical Science Research Project,China(2024HZ04)the Hebei Province Graduate Education and Teaching Reform Research Project,China(YJG2024046)the Innovation Ability Training Program for Postgraduate Students of Hebei Provincial Department of Education,China(CXZZSS2025048)。
文摘A comprehensive assessment of grain supply,demand,and ecosystem service flows is essential for identifying grain movement pathways,ensuring regional grain security,and guiding sustainable management strategies.However,current studies primarily focus on short-term grain provision services while neglecting the spatiotemporal variations in grain flows across different scales.This gap limits the identification of dynamic matching relationships and the formulation of optimization strategies for balancing grain flows.This study examined the spatiotemporal evolution of grain supply and demand in the Beijing-Tianjin-Hebei(BTH)region from 1980 to 2020.Using the Enhanced TwoStep Floating Catchment Area method,the grain provision ecosystem service flows were quantified,the changes in supply–demand matching under different grain flow scenarios were analyzed and the optimal distance threshold for grain flows was investigated.The results revealed that grain production follows a spatial distribution pattern characterized by high levels in the southeast and low levels in the northwest.A significant mismatch exists between supply and demand,and it shows a scale effect.Deficit areas are mainly concentrated in the northwest,while surplus areas are mainly located in the central and southern regions.As the spatial scale increases,the ecosystem service supply–demand ratio(SDR)classification becomes more clustered,while it exhibits greater spatial SDR heterogeneity at smaller scales.This study examined two distinct scenarios of grain provision ecosystem service flow dynamics based on 100 and 200 km distance thresholds.The flow increased significantly,from 2.17 to 11.81million tons in the first scenario and from 2.41 to 12.37 million tons in the second scenario over nearly 40 years,forming a spatial movement pattern from the central and southern regions to the surrounding areas.Large flows were mainly concentrated in the interior of urban centers,with significant outflows between cities such as Baoding,Shijiazhuang,Xingtai,and Hengshui.At the county scale,supply–demand matching patterns remained consistent between the grain flows in the two scenarios.Notably,incorporating grain flow dynamics significantly reduced the number of grain-deficit areas compared to scenarios without grain flow.In 2020,grain-deficit counties decreased by28.79 and 37.88%,and cities by 12.50 and 25.0%under the two scenarios,respectively.Furthermore,the distance threshold for achieving optimal supply and demand matching at the county scale was longer than at the city scale in both grain flow scenarios.This study provides valuable insights into the dynamic relationships and heterogeneous patterns of grain matching,and expands the research perspective on grain and ecosystem service flows across various spatiotemporal scales.
文摘Objectives This study aimed to design and evaluate a detection system for the accidental dislodgement of head-and-neck medical supplies through hand position recognition and tracking in Intensive Care Unit(ICU)patients.Methods We conducted a single-center,prospective,parallel-group feasibility randomized controlled trial.We recruited 80 participants using convenience sampling from the ICU of a hospital in Ningbo City,Zhejiang Province,between March 2025 and June 2025,and they were randomly assigned to either the control group(routine care)or the intervention group(routine care plus image recognition-based detection system).The system continuously tracked patients’hand positions via bedside cameras and generated real-time alarms when hands entered predefined risk zones,notifying on-duty nurses to enable early intervention.System stability was assessed by continuous system uptime;system performance and clinical feasibility were evaluated by the frequencies of risk actions and accidental dislodgement of medical supplies(ADMS).Results All 80 participants completed the intervention,with 40 patients in each group.The baseline characteristics and median observation time of the two groups were balanced(intervention group:48 h/patient vs.control group:49 h/patient).Compared with the control group,the intervention group showed fewer ADMS(2/40 vs.9/40)and detected more risk actions per 100 h(36 vs.25);all system-detected events had corroborating images with complete concordance on manual review,and all nurse-recorded hand-contact events were accurately captured.Conclusions The study demonstrated that the image recognition-based detection system can function stably in clinical settings,providing accurate and continuous surveillance while supporting the early detection of risk actions.By reducing the observation burden and offering real-time cognitive support,the system complements routine nursing care and serves as an additional safety measure in ICU practice.With further optimization and larger multicenter validation,this approach could have the potential to make a significant contribution to the development of smart ICUs and the broader digital transformation of nursing care.
基金supported by the Science and Technology Project of Sichuan Electric Power Company“Power Supply Guarantee Strategy for Urban Distribution Networks Considering Coordination with Virtual Power Plant during Extreme Weather Event”(No.521920230003).
文摘Ensuring reliable power supply in urban distribution networks is a complex and critical task.To address the increased demand during extreme scenarios,this paper proposes an optimal dispatch strategy that considers the coordination with virtual power plants(VPPs).The proposed strategy improves systemflexibility and responsiveness by optimizing the power adjustment of flexible resources.In the proposed strategy,theGaussian Process Regression(GPR)is firstly employed to determine the adjustable range of aggregated power within the VPP,facilitating an assessment of its potential contribution to power supply support.Then,an optimal dispatch model based on a leader-follower game is developed to maximize the benefits of the VPP and flexible resources while guaranteeing the power balance at the same time.To solve the proposed optimal dispatch model efficiently,the constraints of the problem are reformulated and resolved using the Karush-Kuhn-Tucker(KKT)optimality conditions and linear programming duality theorem.The effectiveness of the strategy is illustrated through a detailed case study.
文摘The 15th Five-Year Plan will begin in 2026,amid heightened global technological competition and rapid supply chain changes.At this pivotal moment,the low-altitude economy and commercial aerospace,once seen as futuristic,are quickly transitioning from strategic concepts to large-scale manufacturing industries.These sectors now drive China’s high-quality development and support a new framework for international engagement.
