本文介绍了直接数字频率合成器(DDFS:Direct Digital Frequency Synthesizer)的基本工作原理、主要误差源及改善方法,在此基础上着重讨论了压缩数据以等效增加数据容量的Sunderland算法,并提出了一种改进的数据分割方法,可以在杂散和RO...本文介绍了直接数字频率合成器(DDFS:Direct Digital Frequency Synthesizer)的基本工作原理、主要误差源及改善方法,在此基础上着重讨论了压缩数据以等效增加数据容量的Sunderland算法,并提出了一种改进的数据分割方法,可以在杂散和ROM容量之间取得一个最优值,Matlab仿真结果验证了这一点。展开更多
使用直接数字频率综合(direct digital synthesizer,DDS)技术生成正弦信号时,幅度精度与查找表容量两个条件相互制约,由于容量限制,高精度需要的超大容量查找表在实际中往往无法实现。针对该问题,提出了一种基于压缩查找表的高精度正弦...使用直接数字频率综合(direct digital synthesizer,DDS)技术生成正弦信号时,幅度精度与查找表容量两个条件相互制约,由于容量限制,高精度需要的超大容量查找表在实际中往往无法实现。针对该问题,提出了一种基于压缩查找表的高精度正弦信号生成算法。首先,推导了DDS输出信号精度与查找表容量的关系,为查找表的设计提供了理论依据。然后,依据精度需求构造了一种高效的压缩查找表,给出了查找表容量与压缩比的关系。最后,给出了算法的实现流程,通过仿真验证了信号精度及压缩比,信号幅度为106,精度为10-5时,压缩比达到107倍。展开更多
Peripheral nerves are particularly vulnerable to injuries and are involved in numerous pathologies for which specific treatments are lacking. This review summarizes the pathophysiological features of the most common t...Peripheral nerves are particularly vulnerable to injuries and are involved in numerous pathologies for which specific treatments are lacking. This review summarizes the pathophysiological features of the most common traumatic nerve injury in humans and the different animal models used in nerve regeneration studies. ~Ihe current knowledge concerning Wallerian degeneration and nerve regrowth is then described. Finally, the involvement of intraneural vascularization in these processes is addressed. As intraneural vascularization has been poorly studied, histological experiments were carried out from rat sciatic nerves damaged by a glycerol injection. The results, taken together with the data from literature, suggest that revascularization plays an important role in peripheral nerve regeneration and must therefore be studied more carefully.展开更多
Injury severity, operative technique and nerve regeneration are important factors to consider when constructing a model of peripheral nerve injury. Here, we present a novel peripheral nerve injury model and compare it...Injury severity, operative technique and nerve regeneration are important factors to consider when constructing a model of peripheral nerve injury. Here, we present a novel peripheral nerve injury model and compare it with the complete sciatic nerve transection method. In the experimental group, under a microscope, a 3-mm longitudinal incision was made in the epineurium of the sciatic nerve to reveal the nerve fibers, which were then transected. The small, longitudinal incision in the epineurium was then sutured closed, requiring no stump anastomosis. In the control group, the sciatic nerve was completely transected, and the epineurium was repaired by anastomosis. At 2 and 4 weeks after surgery, Wallerian degeneration was observed in both groups. In the experimental group, at 8 and 12 weeks after surgery, distinct medullary nerve fibers and axons were observed in the injured sciatic nerve. Regular, dense myelin sheaths were visible, as well as some scarring. By 12 weeks, the myelin sheaths were normal and intact, and a tight lamellar structure was observed. Functionally, limb movement and nerve conduction recovered in the injured region between 4 and 12 weeks. The present results demonstrate that longitudinal epineural incision with nerve transection can stably replicate a model of Sunderland grade IV peripheral nerve injury. Compared with the complete sciatic nerve transection model, our method reduced the difficulties of micromanipulation and surgery time, and resulted in good stump restoration, nerve regeneration, and functional recovery.展开更多
文摘本文介绍了直接数字频率合成器(DDFS:Direct Digital Frequency Synthesizer)的基本工作原理、主要误差源及改善方法,在此基础上着重讨论了压缩数据以等效增加数据容量的Sunderland算法,并提出了一种改进的数据分割方法,可以在杂散和ROM容量之间取得一个最优值,Matlab仿真结果验证了这一点。
文摘使用直接数字频率综合(direct digital synthesizer,DDS)技术生成正弦信号时,幅度精度与查找表容量两个条件相互制约,由于容量限制,高精度需要的超大容量查找表在实际中往往无法实现。针对该问题,提出了一种基于压缩查找表的高精度正弦信号生成算法。首先,推导了DDS输出信号精度与查找表容量的关系,为查找表的设计提供了理论依据。然后,依据精度需求构造了一种高效的压缩查找表,给出了查找表容量与压缩比的关系。最后,给出了算法的实现流程,通过仿真验证了信号精度及压缩比,信号幅度为106,精度为10-5时,压缩比达到107倍。
基金supported by a doctoral fellowship from the ‘Conseil Régional du Limousin’ to MC
文摘Peripheral nerves are particularly vulnerable to injuries and are involved in numerous pathologies for which specific treatments are lacking. This review summarizes the pathophysiological features of the most common traumatic nerve injury in humans and the different animal models used in nerve regeneration studies. ~Ihe current knowledge concerning Wallerian degeneration and nerve regrowth is then described. Finally, the involvement of intraneural vascularization in these processes is addressed. As intraneural vascularization has been poorly studied, histological experiments were carried out from rat sciatic nerves damaged by a glycerol injection. The results, taken together with the data from literature, suggest that revascularization plays an important role in peripheral nerve regeneration and must therefore be studied more carefully.
基金supported by a grant from the Plan of the Department of Science and Technology of Hebei Province of China,No.142777105D
文摘Injury severity, operative technique and nerve regeneration are important factors to consider when constructing a model of peripheral nerve injury. Here, we present a novel peripheral nerve injury model and compare it with the complete sciatic nerve transection method. In the experimental group, under a microscope, a 3-mm longitudinal incision was made in the epineurium of the sciatic nerve to reveal the nerve fibers, which were then transected. The small, longitudinal incision in the epineurium was then sutured closed, requiring no stump anastomosis. In the control group, the sciatic nerve was completely transected, and the epineurium was repaired by anastomosis. At 2 and 4 weeks after surgery, Wallerian degeneration was observed in both groups. In the experimental group, at 8 and 12 weeks after surgery, distinct medullary nerve fibers and axons were observed in the injured sciatic nerve. Regular, dense myelin sheaths were visible, as well as some scarring. By 12 weeks, the myelin sheaths were normal and intact, and a tight lamellar structure was observed. Functionally, limb movement and nerve conduction recovered in the injured region between 4 and 12 weeks. The present results demonstrate that longitudinal epineural incision with nerve transection can stably replicate a model of Sunderland grade IV peripheral nerve injury. Compared with the complete sciatic nerve transection model, our method reduced the difficulties of micromanipulation and surgery time, and resulted in good stump restoration, nerve regeneration, and functional recovery.