目的本研究的目的是研究不同的营养评估方法与维持性血液透析患者的预后的关系。方法对我院血液透析中心的83名患者进行营养评估,包括主观综合性营养评估(subjective global assessment,SGA)、营养不良-炎症评分(malnutrition inflammat...目的本研究的目的是研究不同的营养评估方法与维持性血液透析患者的预后的关系。方法对我院血液透析中心的83名患者进行营养评估,包括主观综合性营养评估(subjective global assessment,SGA)、营养不良-炎症评分(malnutrition inflammation score,MIS)和微型营养评定简表(mini nutrition assessment short form,MNA-SF)。同时收集基本资料、辅助检查结果。随访48月(40±13月),采用Kaplan-Meier以及Cox回归分析比较不同营养评估方法与患者全因死亡风险的差别。结果 Kaplan-Meier分析提示:SGA<25分患者的死亡风险较SGA≥25分患者高(P<0.05),MIS>10分组比MIS≤10分死亡风险高(P>0.05)。以MNA-SF分组,MNA-SF≥11分死亡风险低于NA-SF<11分(P>0.05)。多因素Cox回归分析提示,SGA及MIS不同分组仍然与维持性血液透析患者不同的全因死亡风险有关(P<0.05)。结论不同营养评估方法对于维持性血液透析患者长期生存的预测能力不同,SGA法以及MIS法所评价的营养状况与维持性血液透析患者长期的全因死亡风险有较好相关性。展开更多
Objective： Correct nutritional assessment is essential for leukemia patients after hematopoietic stem cell transplantation （HSCT）. This study aimed to investigate the best nutritional assessment method for leukemia...Objective： Correct nutritional assessment is essential for leukemia patients after hematopoietic stem cell transplantation （HSCT）. This study aimed to investigate the best nutritional assessment method for leukemia patients after HSCT, and find the possible nutritional risk of the patients during the transplantation process in order to intervene in the patients with nutritional risks and undernourished patients timely, so that the entire transplantation process could be successfully completed. Methods： A prospective study was performed in 108 leukemia patients after HSCT, and different nutritional assessment methods, including nutritional risk screening 2002 （NRS2002）, mini nutritional assessment （MNA）, subjective globe assessment （SGA） and malnutritional universal screening tools （MUST）, were used. The associations between nutritional status of these patients and nutritional assessment methods were analyzed. Results： A total of 108 patients completed SGA, and 99 patients completed NRS2002, MNA and MUST. During the treatment process, 85.2% of the patients lost weight, wherein, 50% lost weight greater than 5%, and 42.6% had significantly reduced food intake. For nutritional risk assessment, the positive rates of NRS2002, MNA and MUST were 100%, 74.7% and 63.6%, respectively. There was a significant difference （P〈0.05） among the positive rates of NRS2002, MNA and MUST. In undernutrition assessment, the positive rate of SGA （83.3%） was significantly higher than that of MNA （17.2%） （P〈0.05）, and the incidence rate of nutritional risk among leukemia patients _〈30 years old was greater than that of patients 〉30 years old （P〈0.05）. Conclusions： Patients with leukemia were in poor nutritional status during and after HSCT. The leukemia patients 〈30 years old had a greater incidence rate of nutritional risk. As nutritional risk screening tool, the specificity of NRS2002 is not high, but it can be used for evaluating nutritional deficiencies. MNA is a good nutritional risk screening tool, but not an adequate tool for nutritional assessment. If assessment of undernutrition is necessary, the combination of all these screening tools and clinical laboratory indicators should he applied to improve accuracy.展开更多
目的:探讨肝硬化患者营养不良的相关因素。方法:已确诊49例肝硬化住院患者空腹测血常规、血生化、肝纤维化、血凝分析、微量元素测定、尿常规,及人体测量学指标:身高、体重(weight)、上臂围(Mid-upperarmcir cumference,AC)、上臂肌围(M...目的:探讨肝硬化患者营养不良的相关因素。方法:已确诊49例肝硬化住院患者空腹测血常规、血生化、肝纤维化、血凝分析、微量元素测定、尿常规,及人体测量学指标:身高、体重(weight)、上臂围(Mid-upperarmcir cumference,AC)、上臂肌围(Mid-upper arm muscle circumference,AMC)、肱三头肌皮褶厚度(Triceps skin fold thickness,TSF)、髂骨上皮褶厚度(Ilium skin fold thickness,ISF)、腓肠肌围((Gastrocnemius muscle circumference,GC),计算体重指数(Body mass index,BMI)、Pignete指数、比胸围(Ratio of Chest circumference and body Height,C/H)、Rohrer指数、Vervaeck指数等指标110项,采用主观全面营养评价法(Subjective global assessment,SGA)进行营养评估。结果:计量资料应用t检验、计数资料应用X2检验进行单因素分析,筛选出与肝硬化营养不良有关的因素26项,纳入Logistic回归向前逐步选择法(似然比)行多因素分析,GC、AC、ISF、阴离子间隙(AG)4项指标的降低与肝硬化患者营养不良的发生有关系。结论:在采用SGA法评估肝硬化患者营养状况时,应注意GC、AC、ISF及AG的变化。展开更多
文摘目的本研究的目的是研究不同的营养评估方法与维持性血液透析患者的预后的关系。方法对我院血液透析中心的83名患者进行营养评估,包括主观综合性营养评估(subjective global assessment,SGA)、营养不良-炎症评分(malnutrition inflammation score,MIS)和微型营养评定简表(mini nutrition assessment short form,MNA-SF)。同时收集基本资料、辅助检查结果。随访48月(40±13月),采用Kaplan-Meier以及Cox回归分析比较不同营养评估方法与患者全因死亡风险的差别。结果 Kaplan-Meier分析提示:SGA<25分患者的死亡风险较SGA≥25分患者高(P<0.05),MIS>10分组比MIS≤10分死亡风险高(P>0.05)。以MNA-SF分组,MNA-SF≥11分死亡风险低于NA-SF<11分(P>0.05)。多因素Cox回归分析提示,SGA及MIS不同分组仍然与维持性血液透析患者不同的全因死亡风险有关(P<0.05)。结论不同营养评估方法对于维持性血液透析患者长期生存的预测能力不同,SGA法以及MIS法所评价的营养状况与维持性血液透析患者长期的全因死亡风险有较好相关性。
文摘Objective： Correct nutritional assessment is essential for leukemia patients after hematopoietic stem cell transplantation （HSCT）. This study aimed to investigate the best nutritional assessment method for leukemia patients after HSCT, and find the possible nutritional risk of the patients during the transplantation process in order to intervene in the patients with nutritional risks and undernourished patients timely, so that the entire transplantation process could be successfully completed. Methods： A prospective study was performed in 108 leukemia patients after HSCT, and different nutritional assessment methods, including nutritional risk screening 2002 （NRS2002）, mini nutritional assessment （MNA）, subjective globe assessment （SGA） and malnutritional universal screening tools （MUST）, were used. The associations between nutritional status of these patients and nutritional assessment methods were analyzed. Results： A total of 108 patients completed SGA, and 99 patients completed NRS2002, MNA and MUST. During the treatment process, 85.2% of the patients lost weight, wherein, 50% lost weight greater than 5%, and 42.6% had significantly reduced food intake. For nutritional risk assessment, the positive rates of NRS2002, MNA and MUST were 100%, 74.7% and 63.6%, respectively. There was a significant difference （P〈0.05） among the positive rates of NRS2002, MNA and MUST. In undernutrition assessment, the positive rate of SGA （83.3%） was significantly higher than that of MNA （17.2%） （P〈0.05）, and the incidence rate of nutritional risk among leukemia patients _〈30 years old was greater than that of patients 〉30 years old （P〈0.05）. Conclusions： Patients with leukemia were in poor nutritional status during and after HSCT. The leukemia patients 〈30 years old had a greater incidence rate of nutritional risk. As nutritional risk screening tool, the specificity of NRS2002 is not high, but it can be used for evaluating nutritional deficiencies. MNA is a good nutritional risk screening tool, but not an adequate tool for nutritional assessment. If assessment of undernutrition is necessary, the combination of all these screening tools and clinical laboratory indicators should he applied to improve accuracy.
文摘目的:探讨肝硬化患者营养不良的相关因素。方法:已确诊49例肝硬化住院患者空腹测血常规、血生化、肝纤维化、血凝分析、微量元素测定、尿常规,及人体测量学指标:身高、体重(weight)、上臂围(Mid-upperarmcir cumference,AC)、上臂肌围(Mid-upper arm muscle circumference,AMC)、肱三头肌皮褶厚度(Triceps skin fold thickness,TSF)、髂骨上皮褶厚度(Ilium skin fold thickness,ISF)、腓肠肌围((Gastrocnemius muscle circumference,GC),计算体重指数(Body mass index,BMI)、Pignete指数、比胸围(Ratio of Chest circumference and body Height,C/H)、Rohrer指数、Vervaeck指数等指标110项,采用主观全面营养评价法(Subjective global assessment,SGA)进行营养评估。结果:计量资料应用t检验、计数资料应用X2检验进行单因素分析,筛选出与肝硬化营养不良有关的因素26项,纳入Logistic回归向前逐步选择法(似然比)行多因素分析,GC、AC、ISF、阴离子间隙(AG)4项指标的降低与肝硬化患者营养不良的发生有关系。结论:在采用SGA法评估肝硬化患者营养状况时,应注意GC、AC、ISF及AG的变化。
