To realize equal power splitting at two arbitrary gigahertz-frequencies, this paper presents a new type of Wilkinson dual frequency power divider, consisting of three-section transmission lines and a series RLC(resist...To realize equal power splitting at two arbitrary gigahertz-frequencies, this paper presents a new type of Wilkinson dual frequency power divider, consisting of three-section transmission lines and a series RLC(resistor, inductor and capacitor)circuit. By equating the [ABCD] matrix of the proposed circuit to that of the quarter-wave impedance transformer, coupled with even/odd mode analyses, the design equations of the proposed network are derived. For verification, two dual-frequency power dividers with dual-band operating frequencies at 0.6 GHz and 3.0 GHz, and 3.8 GHz and 10 GHz respectively are designed and simulated. Simulation results show that the dual-band ratio of the proposed power divider can be as large as 5. Comparisons of the simulation results at X-band and S-band with different power dividers indicate that the proposed dual-band power divider performs better under the scenario of the upper operating frequency extending to X-band.展开更多
A miniaturized square resonator bandpass filter with circular stubs is designed, fabricated, and characterized. Analytical calculations were carried out to determine the critical filter parameters and the design was o...A miniaturized square resonator bandpass filter with circular stubs is designed, fabricated, and characterized. Analytical calculations were carried out to determine the critical filter parameters and the design was optimized using a 3D electromagnetic finite-element solver. The measured results were in good agreement with the designed results. The proposed filter exhibits significant improvement in bandwidth compared to the conventional square resonator bandpass filters.展开更多
目的旨在通过生物信息学分析结合实验验证,探讨PCBP1(Poly(rC)-Binding Protein 1)在胃癌组织中的表达特征及其临床意义,对其与铁死亡主要调控因子STUB1(STIP1 Homology and U-Box Containing Protein 1)的关系研究。并通过免疫组化实...目的旨在通过生物信息学分析结合实验验证,探讨PCBP1(Poly(rC)-Binding Protein 1)在胃癌组织中的表达特征及其临床意义,对其与铁死亡主要调控因子STUB1(STIP1 Homology and U-Box Containing Protein 1)的关系研究。并通过免疫组化实验验证PCBP1与STUB1在胃癌中的表达模式及其与临床病理特征的关系。为新型胃癌靶向治疗策略提供重要的理论支撑和潜在的干预靶点。方法从TIMER 2.0在线分析网站中获取PCBP1在胃癌及癌旁组织的基因表达数据。利用癌症基因组图谱(The Cancer Genome Atlas,TCGA)数据库中胃癌数据(STAD)进行KEGG通路富集分析,并揭示其潜在作用机制;在铁死亡调控通路中找出主要调控因子STUB1。随后,采用免疫组化法检测33例胃癌组织及对应癌旁组织中PCBP1和STUB1的表达情况。将所收集的病例依据不同的分化程度、年龄、性别、肿瘤浸润深度、TNM分期及病理学形态进行分组,观察二者的阳性表达率,采用χ^(2)检验分析两者之间及其与临床和病理特征间的相关性,进一步探讨PCBP1和STUB1与胃癌恶性程度的关系。结果免疫组化结果显示PCBP1在癌组织中的阳性表达率为69.7%,明显高于癌旁组织中的阳性表达率48.5%;STUB1在癌组织中的阳性表达率为39.4%,低于癌旁组织中的阳性表达率54.5%,两者差异均有统计学意义(P<0.05)。PCBP1的阳性表达率与肿瘤分化程度、淋巴结转移及Lauren分型有相关性(P<0.05);与患者的年龄、性别、浸润深度、临床分期、神经浸润、脉管侵犯无相关性(P>0.05)。STUB1的阳性表达率与肿瘤分化程度、浸润深度、淋巴结转移及Lauren分型有相关性(P<0.05),但与患者的年龄、性别、临床分期、神经浸润、脉管侵犯无相关性(P>0.05)。PCBP1(癌)与STUB1(癌)的Spearman相关系数为-0.413,P为0.017,表明两者之间存在显著的负相关性。结论PCBP1可通过调控铁死亡通路中主要调控因子STUB1参与胃癌的恶性进展。为胃癌的分子机制探索及潜在治疗靶点提供了新的理论依据。展开更多
With the principles of microwave circuits and semiconductor device physics, two microwave power device test circuits combined with a test fixture are designed and simulated, whose properties are evaluated by a paramet...With the principles of microwave circuits and semiconductor device physics, two microwave power device test circuits combined with a test fixture are designed and simulated, whose properties are evaluated by a parameter network analyzer within the frequency range from 3 to 8GHz. The simulation and experimental results verify that the test circuit with a radial stub is better than that without. As an example, a C-band AlGaN/GaN HEMT microwave power device is tested with the designed circuit and fixture. With a 5.4GHz microwave input signal,the maximum gain is 8.75dB,and the maximum output power is 33.2dBm.展开更多
OSPF路由协议是一种典型的链路状态(Link-state)的路由协议,一般用于同一个路由域内。在这里,路由域是指一个自治系统(Autonomous System),即AS,它是指一组通过统一的路由政策或路由协议互相交换路由信息的网络。在这个AS中,所有的OSPF...OSPF路由协议是一种典型的链路状态(Link-state)的路由协议,一般用于同一个路由域内。在这里,路由域是指一个自治系统(Autonomous System),即AS,它是指一组通过统一的路由政策或路由协议互相交换路由信息的网络。在这个AS中,所有的OSPF路由器都维护一个相同的描述这个AS结构的数据库,该数据库中存放的是路由域中相应链路的状态信息,OSPF路由器正是通过这个数据库计算出其OSPF路由表的,作为一种链路状态的路由协议,OSPF将链路状态广播数据LSA(Link State Advertisement)传送给在某一区域内的所有路由器,这一点与距离矢量路由协议不同。运行距离矢量路由协议的路由器是将部分或全部的路由表传递给与其相邻的路由器。展开更多
基金Supported by National Natural Science Foundation of China,11447118,11247032,11365011Youth Science Foundation of Science and Technology Department of Jiangxi Province,20151BAB212004,20151BAB212012~~
文摘To realize equal power splitting at two arbitrary gigahertz-frequencies, this paper presents a new type of Wilkinson dual frequency power divider, consisting of three-section transmission lines and a series RLC(resistor, inductor and capacitor)circuit. By equating the [ABCD] matrix of the proposed circuit to that of the quarter-wave impedance transformer, coupled with even/odd mode analyses, the design equations of the proposed network are derived. For verification, two dual-frequency power dividers with dual-band operating frequencies at 0.6 GHz and 3.0 GHz, and 3.8 GHz and 10 GHz respectively are designed and simulated. Simulation results show that the dual-band ratio of the proposed power divider can be as large as 5. Comparisons of the simulation results at X-band and S-band with different power dividers indicate that the proposed dual-band power divider performs better under the scenario of the upper operating frequency extending to X-band.
文摘A miniaturized square resonator bandpass filter with circular stubs is designed, fabricated, and characterized. Analytical calculations were carried out to determine the critical filter parameters and the design was optimized using a 3D electromagnetic finite-element solver. The measured results were in good agreement with the designed results. The proposed filter exhibits significant improvement in bandwidth compared to the conventional square resonator bandpass filters.
文摘目的旨在通过生物信息学分析结合实验验证,探讨PCBP1(Poly(rC)-Binding Protein 1)在胃癌组织中的表达特征及其临床意义,对其与铁死亡主要调控因子STUB1(STIP1 Homology and U-Box Containing Protein 1)的关系研究。并通过免疫组化实验验证PCBP1与STUB1在胃癌中的表达模式及其与临床病理特征的关系。为新型胃癌靶向治疗策略提供重要的理论支撑和潜在的干预靶点。方法从TIMER 2.0在线分析网站中获取PCBP1在胃癌及癌旁组织的基因表达数据。利用癌症基因组图谱(The Cancer Genome Atlas,TCGA)数据库中胃癌数据(STAD)进行KEGG通路富集分析,并揭示其潜在作用机制;在铁死亡调控通路中找出主要调控因子STUB1。随后,采用免疫组化法检测33例胃癌组织及对应癌旁组织中PCBP1和STUB1的表达情况。将所收集的病例依据不同的分化程度、年龄、性别、肿瘤浸润深度、TNM分期及病理学形态进行分组,观察二者的阳性表达率,采用χ^(2)检验分析两者之间及其与临床和病理特征间的相关性,进一步探讨PCBP1和STUB1与胃癌恶性程度的关系。结果免疫组化结果显示PCBP1在癌组织中的阳性表达率为69.7%,明显高于癌旁组织中的阳性表达率48.5%;STUB1在癌组织中的阳性表达率为39.4%,低于癌旁组织中的阳性表达率54.5%,两者差异均有统计学意义(P<0.05)。PCBP1的阳性表达率与肿瘤分化程度、淋巴结转移及Lauren分型有相关性(P<0.05);与患者的年龄、性别、浸润深度、临床分期、神经浸润、脉管侵犯无相关性(P>0.05)。STUB1的阳性表达率与肿瘤分化程度、浸润深度、淋巴结转移及Lauren分型有相关性(P<0.05),但与患者的年龄、性别、临床分期、神经浸润、脉管侵犯无相关性(P>0.05)。PCBP1(癌)与STUB1(癌)的Spearman相关系数为-0.413,P为0.017,表明两者之间存在显著的负相关性。结论PCBP1可通过调控铁死亡通路中主要调控因子STUB1参与胃癌的恶性进展。为胃癌的分子机制探索及潜在治疗靶点提供了新的理论依据。
文摘With the principles of microwave circuits and semiconductor device physics, two microwave power device test circuits combined with a test fixture are designed and simulated, whose properties are evaluated by a parameter network analyzer within the frequency range from 3 to 8GHz. The simulation and experimental results verify that the test circuit with a radial stub is better than that without. As an example, a C-band AlGaN/GaN HEMT microwave power device is tested with the designed circuit and fixture. With a 5.4GHz microwave input signal,the maximum gain is 8.75dB,and the maximum output power is 33.2dBm.
文摘OSPF路由协议是一种典型的链路状态(Link-state)的路由协议,一般用于同一个路由域内。在这里,路由域是指一个自治系统(Autonomous System),即AS,它是指一组通过统一的路由政策或路由协议互相交换路由信息的网络。在这个AS中,所有的OSPF路由器都维护一个相同的描述这个AS结构的数据库,该数据库中存放的是路由域中相应链路的状态信息,OSPF路由器正是通过这个数据库计算出其OSPF路由表的,作为一种链路状态的路由协议,OSPF将链路状态广播数据LSA(Link State Advertisement)传送给在某一区域内的所有路由器,这一点与距离矢量路由协议不同。运行距离矢量路由协议的路由器是将部分或全部的路由表传递给与其相邻的路由器。
