A multifractal model is developed to connect the Lagrangian multifractal dimensions with their Eulerian counterparts. We propose that the characteristic time scale of a Lagrangian quantity should be the Lagrangian tim...A multifractal model is developed to connect the Lagrangian multifractal dimensions with their Eulerian counterparts. We propose that the characteristic time scale of a Lagrangian quantity should be the Lagrangian time scale, and it should not be the Eulerian time scale which was widely used in previous studies on Lagrangian statistics. Using the present model, we can obtain the scaling exponents of Lagrangian velocity structure functions from the existing data or models of scaling exponents of Eulerian velocity structure functions. This model is validated by comparing its prediction with the results of experiments, direct numerical simulations, and the previous theoretical models. The comparison shows that the proposed model can better predict the scaling exponents of Lagrangian velocity structure functions, especially for orders larger than 6.展开更多
Streamwise evolution of longitudinal and transverse velocity structure functions in a decaying homogeneous and nearly isotropic turbulence is reported for Reynolds numbers Reλ up to 720. First, two theoretical relati...Streamwise evolution of longitudinal and transverse velocity structure functions in a decaying homogeneous and nearly isotropic turbulence is reported for Reynolds numbers Reλ up to 720. First, two theoretical relations between longitudinal and transverse structure functions are examined in the light of recently derived relations and the results show that the low-order transverse structure functions can be well approximated by longitudinal ones within the sub-inertial range. Reconstruction of fourth-order transverse structure functions with a recently proposed relation by Grauer et al. is comparatively less valid than the relation already proposed by Antonia et al. Secondly, extended self-similarity methods are used to measure the scaling exponents up to order eight and the streamwise evolution of scaling exponents is explored. The scaling exponents of longitudinal structure functions are, at first location, close to Zybin's model, and at the fourth location, close to She–Leveque model. No obvious trend is found for the streamwise evolution of longitudinal scaling exponents, whereas, on the contrary, transverse scaling exponents become slightly smaller with the development of a steamwise direction. Finally, the stremwise variation of the order-dependent isotropy ratio indicates the turbulence at the last location is closer to isotropic than the other three locations.展开更多
Nucleon unpolarized structure functions in the ep elastic scattering are discussed. A new unpolarized structure function F^-3 due to the two-photon-exchange is given. Numerical results of the new structure function in...Nucleon unpolarized structure functions in the ep elastic scattering are discussed. A new unpolarized structure function F^-3 due to the two-photon-exchange is given. Numerical results of the new structure function in the limit of x →1 are displayed.展开更多
The time sequence of longitudinal velocity component at different vertical locations in turbulent boundary layer was finely measured in a wind tunnel. The concept of coarse_grained velocity structure functions, which ...The time sequence of longitudinal velocity component at different vertical locations in turbulent boundary layer was finely measured in a wind tunnel. The concept of coarse_grained velocity structure functions, which describes the relative motions of straining and compressing for multi_scale eddy structures in turbulent flows, was put forward based on the theory of locally multi_scale average. Based on the consistency between coarse_grained velocity structure function and Harr wavelet transformation,detecting method was presented, by which the coherent structures and their intermittency was identified by multi_scale flatness factor calculated by locally average structure function. Phase_averaged evolution course for multi_scale coherent eddy structures in wall turbulence were extracted by this conditional sampling to educe scheme. The dynamics course of multi_scale coherent eddy structures and their effects on statistics of turbulent flows were studied.展开更多
We discuss the nucleon spin structure function g<SUB>1</SUB> and the difference between the proton and neutron targets , based on quark model calculation. Quark-hadron duality for the nucleon spin structur...We discuss the nucleon spin structure function g<SUB>1</SUB> and the difference between the proton and neutron targets , based on quark model calculation. Quark-hadron duality for the nucleon spin structure function is also analyzed. Effects of the Δ(1232) and Roper P<SUB>11</SUB>(1440) resonances on the spin structure function and on the difference are mentioned. The results of different models for the Roper resonance are also addressed.展开更多
The instanton induced cross section in deep inelastic kinematics is a subject which people are tendentious to investigate it. Instanton induced contributions are well defined for the nucleon structure function. The no...The instanton induced cross section in deep inelastic kinematics is a subject which people are tendentious to investigate it. Instanton induced contributions are well defined for the nucleon structure function. The non-perturbative contribution to the quark distributions of structure function, F2（x, Q2）, is considered within an instanton model for the QCD vacuum. We find that the structure function may possess numerically large non-perterbative contributions which are related to the violation of chirality and correspond to the correction of parton distribution of the leading twist. It is shown that the instantons give a negative contribution to the structure function at the NLO approximation. A comparison between our results, considering instantaon effect, and the case when we do not take this effect is done. Taking into account the instanton size, p, via the modified running coupling constant we get to a good agreement between our results at the NLO and NNLO approximations and the available experimental data, specially at the low values of the Bjorken variable x 〈 0.1 which confirms the validity of our calculations.展开更多
Since the famous work by Kolmogorov on incompressible turbulence,the structure-function theory has been a key foundation of modern turbulence study.Due to the simplicity of Burgers turbulence,structure functions are c...Since the famous work by Kolmogorov on incompressible turbulence,the structure-function theory has been a key foundation of modern turbulence study.Due to the simplicity of Burgers turbulence,structure functions are calculated to arbitrary orders,which provides numerous implications for other compressible turbulent systems.We present the derivation of exact forcing-scale resolving expressions for high-order structure functions of the burgers turbulence.Compared with the previous theories,where the structure functions are calculated in the inertial range based on the statistics of shocks,our expressions link high-order structure functions in different orders without extra information on the flow structure and are valid beyond the inertial range,therefore they are easily checked by numerical simulations.展开更多
Closure models started from Chou＇s work have been developed for more than 70 years, aiming at providing analytical tools to describe turbulent flows in the spectral space. In this study, a preliminary attempt is pres...Closure models started from Chou＇s work have been developed for more than 70 years, aiming at providing analytical tools to describe turbulent flows in the spectral space. In this study, a preliminary attempt is presented to introduce a closure model in the physical space, using the velocity structure functions as key parameters. The present closure model appears to qualitatively reproduce the asymptotic scaling behav- iors at small and large scales, despite some inappropriate behaviors such as oscillations. Therefore, further improvements of the present model are expected to provide appropriate descriptions of turbulent flows in the physical space.展开更多
Understanding the acid resistance mechanism of S.mutans is crucial for preventing dental caries.FtsZ is the core protein for cell division in bacteria that can polymerize into Z-rings and drive cytokinesis.Our previou...Understanding the acid resistance mechanism of S.mutans is crucial for preventing dental caries.FtsZ is the core protein for cell division in bacteria that can polymerize into Z-rings and drive cytokinesis.Our previous study revealed that the FtsZ in S.mutans(SmFtsZ) has higher self-assembly and GTPase activity under acidic stress,which may be responsible for acid resistance and ca riogenesis of S.mutans.However,the functional structure mechanism of SmFtsZ under low pH conditions is still unclear.Here,we further reported the crystal structure of S.mutans FtsZ,revealing a unique lateral interface.Through protein polymerization and GTPase activity assay,we experimentally demonstrated that the mutation of Arg68 on this lateral interface significantly reduced the functional activity of FtsZ in an acidic environment.The phenotype assay and rat caries model further showed that the mutation of Arg68 effectively inhibited the acid resistance of S.mutans and the occurrence and progress of dental caries in vivo.By employing a molecular dynamics simulation analysis,we conclude that the mutation of Arg68 disrupts the conformation change necessary for SmFtsZ polymerization under acidic conditions.Our study proposes a novel mechanism to maintain FtsZ function in bacteria and could be a potential target for antimicrobial drugs to inhibit the growth of S.mutans in acidic environments.展开更多
Functionally graded cellular structures(FGCSs)have a multitude of applications to a wide range of industries.Utilising the ever-progressing technology of additive manufacturing(AM),FGCSs can be applied to control mate...Functionally graded cellular structures(FGCSs)have a multitude of applications to a wide range of industries.Utilising the ever-progressing technology of additive manufacturing(AM),FGCSs can be applied to control material grading and achieve the desired mechanical properties.The current study explores the design and optimisation of FGCSs for AM,with a focus on improving the compression and impact performance of below knee(BK)prosthetic limbs made of thermoplastic polyurethane(TPU).A multiscale research methodology integrating topology optimization(TO),finite element analysis(FEA),and design of experiments(Do E)was adopted to optimise lattice structures in terms of stiffness and lightweight properties.Two-unit cell designs were considered in the study:Schwarz P gyroid and body-centered cubic(BCC).Response surface methodology(RSM)was implemented to analyse the effect of minimum and maximum cell wall thickness,cell size,and unit cell type on the mechanical performance of TPU FGCS structures.The results indicated that a Schwarz P FGCS structure with cell size,minimum and maximum cell wall thickness of 6,0.9 and 2.8 mm,respectively,could be optimal for a compromise between performance and weight.In this optimized case,stiffness and volume fraction values of 684 N/mm and 0.64 were obtained,respectively.The study also presents a proof-of-concept design for a BK prosthetic damper,highlighting the potential of FGCSs to enhance patient comfort,reduce manufacturing costs,and enable personalised designs through 3D scanning and AM.The obtained results could be a step forward towards the incorporation of AM technologies in prosthetics,offering a pathway to lightweight,cost-effective,and functionally tailored solutions.展开更多
Extended quark distribution functions are presented obtained by fitting a large amount of experimental data of the l-A DIS process on the basis of an improved nuclear density model. The experimental data of l-A DIS pr...Extended quark distribution functions are presented obtained by fitting a large amount of experimental data of the l-A DIS process on the basis of an improved nuclear density model. The experimental data of l-A DIS processes with A≥ 3 in the region 0.0010 ≤ x ≤ 0.9500 are quite satisfactorily described by using the extended formulae. Our knowledge of the influence of nuclear matter on the quark distributions is deepened.展开更多
Cuticular wax plays a major role in the growth and storage of plant fruits.The cuticular wax coating,which covers the outermost layer of a fruit’s epidermal cells,is insoluble in water.Cuticular wax is mainly compose...Cuticular wax plays a major role in the growth and storage of plant fruits.The cuticular wax coating,which covers the outermost layer of a fruit’s epidermal cells,is insoluble in water.Cuticular wax is mainly composed of very long-chain fatty acids(VLCFAs);their derivatives,including esters,primary alcohols,secondary alcohols,aldehydes,and ketones;and triterpenoids.This complex mixture of lipids is probably biosynthesized in the epidermal cells of most plants and exuded onto the surface.Cuticular wax not only makes the fruit less susceptible to microbial infection but also reduces mechanical damage to the fruit,thereby maintaining the fruit’s commodity value.To date,research has mostly focused on the changes,function,and regulation of fruit wax before harvest,while ignoring the changes and functions of wax in fruit storage.This paper reviews on the composition,structure,and metabolic regulation of cuticular wax in fruits.It also focuses on postharvest factors affecting wax composition,such as storage temperature,relative humidity(RH),gas atmosphere,and as exogenous hormones;and the effects of wax on fruit postharvest quality,including water dispersion,fruit softening,physiological disorders,and disease resistance.These summaries may be of assistance in better understanding the changes in cuticular wax in postharvest fruit and the resulting effects on fruit quality.展开更多
Hydrogel scaffolds have numerous potential applications in the tissue engineering field.However,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and hi...Hydrogel scaffolds have numerous potential applications in the tissue engineering field.However,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and high mechanical properties.Inspired by Chinese ramen,we propose a universal fabricating method(printing-P,training-T,cross-linking-C,PTC&PCT)for tough hydrogel scaffolds to fill this gap.First,3D printing fabricates a hydrogel scaffold with desired structures(P).Then,the scaffold could have extraordinarily high mechanical properties and functional surface structure by cycle mechanical training with salting-out assistance(T).Finally,the training results are fixed by photo-cross-linking processing(C).The tough gelatin hydrogel scaffolds exhibit excellent tensile strength of 6.66 MPa(622-fold untreated)and have excellent biocompatibility.Furthermore,this scaffold possesses functional surface structures from nanometer to micron to millimeter,which can efficiently induce directional cell growth.Interestingly,this strategy can produce bionic human tissue with mechanical properties of 10 kPa-10 MPa by changing the type of salt,and many hydrogels,such as gelatin and silk,could be improved with PTC or PCT strategies.Animal experiments show that this scaffold can effectively promote the new generation of muscle fibers,blood vessels,and nerves within 4 weeks,prompting the rapid regeneration of large-volume muscle loss injuries.展开更多
The development of the socialist market economy demands the furtherintensification of the reform of the management operating system (MOS)of the state-owned assets, the strengthening of the efficiency in the man-agemen...The development of the socialist market economy demands the furtherintensification of the reform of the management operating system (MOS)of the state-owned assets, the strengthening of the efficiency in the man-agement of state-owned assets,and the improvement of the operating bene-展开更多
With the verification of the State Organization Establishment Committee and the approval of the State Council, the CAS is now an institutional organization under the direct supervision of the State Council. It is both...With the verification of the State Organization Establishment Committee and the approval of the State Council, the CAS is now an institutional organization under the direct supervision of the State Council. It is both the highest academic institution and the most comprehensive research center in natural sciences in China.展开更多
Mimicking the electric microenvironment of natural tissue is a promising strategy for developing biomedical implants. However, current research has not taken biomimetic electrical functional units into consideration w...Mimicking the electric microenvironment of natural tissue is a promising strategy for developing biomedical implants. However, current research has not taken biomimetic electrical functional units into consideration when designing biomedical implants. In this research, ordered structures with Schottky heterojunction functional unit (OSSH) were constructed on titanium implant surfaces for bone regeneration regulation. The Schottky heterojunction functional unit is composed of periodically distributed titanium microdomain and titanium oxide microdomain with different carrier densities and surface potentials. The OSSH regulates the M2-type polarization of macrophages to a regenerative immune response by activating the PI3K-AKT-mTOR signal pathway and further promotes osteogenic differentiation of rat bone marrow mesenchymal stem cells. This work provides fundamental insights into the biological effects driven by the Schottky heterojunction functional units that can electrically modulate osteogenesis.展开更多
Based on a simple nonrelativistic constituent quark model, the nucleon structure function F<SUB>2</SUB> in the resonance region is estimated by taking the contributions from low-lying nucleon resonances in...Based on a simple nonrelativistic constituent quark model, the nucleon structure function F<SUB>2</SUB> in the resonance region is estimated by taking the contributions from low-lying nucleon resonances into account. Calculated results are employed to study quark-hardon duality in the nucleon electron scattering process by comparing them to the scaling behavior from the data in deep inelastic scattering region.展开更多
By employing the parametrization form of the nucleon spin structure functionin the resonance region, which includes the contributions of the resonance peaks and of nonresonancebackground, we study Bloom—Oilman quark-...By employing the parametrization form of the nucleon spin structure functionin the resonance region, which includes the contributions of the resonance peaks and of nonresonancebackground, we study Bloom—Oilman quark-hadron duality of g_1 both in the inelastic resonanceregion and elastic one.展开更多
The aging process is an inexorable fact throughout our lives and is considered a major factor in develo ping neurological dysfunctions associated with cognitive,emotional,and motor impairments.Aging-associated neurode...The aging process is an inexorable fact throughout our lives and is considered a major factor in develo ping neurological dysfunctions associated with cognitive,emotional,and motor impairments.Aging-associated neurodegenerative diseases are characterized by the progressive loss of neuronal structure and function.展开更多
The evaluation of thermal resistance constitution for packaged A1GaN/GaN high electron mobility transistor （HEMT） by structure function method is proposed in this paper. The evaluation is based on the transient heat...The evaluation of thermal resistance constitution for packaged A1GaN/GaN high electron mobility transistor （HEMT） by structure function method is proposed in this paper. The evaluation is based on the transient heating measurement of the A1GaN/GaN HEMT by pulsed electrical temperature sensitive parameter method. The extracted chip-level and package-level thermal resistances of the packaged multi-finger A1GaN/GaN HEMT with 400μm SiC substrate are 22.5 K/W and 7.2 K/W respectively, which provides a non-invasive method to evaluate the chip-level thermal resistance of packaged A1GaN/GaN HEMTs. It is also experimentally proved that the extraction of the chip- level thermal resistance by this proposed method is not influenced by package form of the tested device and temperature boundary condition of measurement stage.展开更多
基金supported by the National Natural Science Foundation of China(11072247,11021262,and 11232011)National Natural Science Associate Foundation of China(NSAF)(U1230126)973 program of China(2013CB834100)
文摘A multifractal model is developed to connect the Lagrangian multifractal dimensions with their Eulerian counterparts. We propose that the characteristic time scale of a Lagrangian quantity should be the Lagrangian time scale, and it should not be the Eulerian time scale which was widely used in previous studies on Lagrangian statistics. Using the present model, we can obtain the scaling exponents of Lagrangian velocity structure functions from the existing data or models of scaling exponents of Eulerian velocity structure functions. This model is validated by comparing its prediction with the results of experiments, direct numerical simulations, and the previous theoretical models. The comparison shows that the proposed model can better predict the scaling exponents of Lagrangian velocity structure functions, especially for orders larger than 6.
基金Project supported by the National Natural Science Foundation of China （Grant Nos. 11272196, 11002085, and 11032007） and the Key Project of Education Commission of Shanghai Municipal, China （Grant No. 11ZZ87）.
文摘Streamwise evolution of longitudinal and transverse velocity structure functions in a decaying homogeneous and nearly isotropic turbulence is reported for Reynolds numbers Reλ up to 720. First, two theoretical relations between longitudinal and transverse structure functions are examined in the light of recently derived relations and the results show that the low-order transverse structure functions can be well approximated by longitudinal ones within the sub-inertial range. Reconstruction of fourth-order transverse structure functions with a recently proposed relation by Grauer et al. is comparatively less valid than the relation already proposed by Antonia et al. Secondly, extended self-similarity methods are used to measure the scaling exponents up to order eight and the streamwise evolution of scaling exponents is explored. The scaling exponents of longitudinal structure functions are, at first location, close to Zybin's model, and at the fourth location, close to She–Leveque model. No obvious trend is found for the streamwise evolution of longitudinal scaling exponents, whereas, on the contrary, transverse scaling exponents become slightly smaller with the development of a steamwise direction. Finally, the stremwise variation of the order-dependent isotropy ratio indicates the turbulence at the last location is closer to isotropic than the other three locations.
基金supported by National Natural Sciences Foundation under Grant Nos.10475088 and 10775148CAS under Grant No.KJCX3-SYW-N2
文摘Nucleon unpolarized structure functions in the ep elastic scattering are discussed. A new unpolarized structure function F^-3 due to the two-photon-exchange is given. Numerical results of the new structure function in the limit of x →1 are displayed.
文摘The time sequence of longitudinal velocity component at different vertical locations in turbulent boundary layer was finely measured in a wind tunnel. The concept of coarse_grained velocity structure functions, which describes the relative motions of straining and compressing for multi_scale eddy structures in turbulent flows, was put forward based on the theory of locally multi_scale average. Based on the consistency between coarse_grained velocity structure function and Harr wavelet transformation,detecting method was presented, by which the coherent structures and their intermittency was identified by multi_scale flatness factor calculated by locally average structure function. Phase_averaged evolution course for multi_scale coherent eddy structures in wall turbulence were extracted by this conditional sampling to educe scheme. The dynamics course of multi_scale coherent eddy structures and their effects on statistics of turbulent flows were studied.
文摘We discuss the nucleon spin structure function g<SUB>1</SUB> and the difference between the proton and neutron targets , based on quark model calculation. Quark-hadron duality for the nucleon spin structure function is also analyzed. Effects of the Δ(1232) and Roper P<SUB>11</SUB>(1440) resonances on the spin structure function and on the difference are mentioned. The results of different models for the Roper resonance are also addressed.
文摘The instanton induced cross section in deep inelastic kinematics is a subject which people are tendentious to investigate it. Instanton induced contributions are well defined for the nucleon structure function. The non-perturbative contribution to the quark distributions of structure function, F2（x, Q2）, is considered within an instanton model for the QCD vacuum. We find that the structure function may possess numerically large non-perterbative contributions which are related to the violation of chirality and correspond to the correction of parton distribution of the leading twist. It is shown that the instantons give a negative contribution to the structure function at the NLO approximation. A comparison between our results, considering instantaon effect, and the case when we do not take this effect is done. Taking into account the instanton size, p, via the modified running coupling constant we get to a good agreement between our results at the NLO and NNLO approximations and the available experimental data, specially at the low values of the Bjorken variable x 〈 0.1 which confirms the validity of our calculations.
基金supported by the National Natural Science Foundation of China(Grant No.92052102).
文摘Since the famous work by Kolmogorov on incompressible turbulence,the structure-function theory has been a key foundation of modern turbulence study.Due to the simplicity of Burgers turbulence,structure functions are calculated to arbitrary orders,which provides numerous implications for other compressible turbulent systems.We present the derivation of exact forcing-scale resolving expressions for high-order structure functions of the burgers turbulence.Compared with the previous theories,where the structure functions are calculated in the inertial range based on the statistics of shocks,our expressions link high-order structure functions in different orders without extra information on the flow structure and are valid beyond the inertial range,therefore they are easily checked by numerical simulations.
基金supported by the National Natural Science Foundation of China(Nos.11572025,11202013,and 51420105008)
文摘Closure models started from Chou＇s work have been developed for more than 70 years, aiming at providing analytical tools to describe turbulent flows in the spectral space. In this study, a preliminary attempt is presented to introduce a closure model in the physical space, using the velocity structure functions as key parameters. The present closure model appears to qualitatively reproduce the asymptotic scaling behav- iors at small and large scales, despite some inappropriate behaviors such as oscillations. Therefore, further improvements of the present model are expected to provide appropriate descriptions of turbulent flows in the physical space.
基金supported by the Beijing Natural Science Foundation:7222220National Natural Science Foundation of China (82001039)+2 种基金Research Foundation of Peking University School and Hospital of Stomatology:PKUSS20230117The Fundamental Research Funds for the Central UniversitiesYoung Elite Scientist Sponsorship Program by CAST (No.2019QNRC001 to Y.L.L)。
文摘Understanding the acid resistance mechanism of S.mutans is crucial for preventing dental caries.FtsZ is the core protein for cell division in bacteria that can polymerize into Z-rings and drive cytokinesis.Our previous study revealed that the FtsZ in S.mutans(SmFtsZ) has higher self-assembly and GTPase activity under acidic stress,which may be responsible for acid resistance and ca riogenesis of S.mutans.However,the functional structure mechanism of SmFtsZ under low pH conditions is still unclear.Here,we further reported the crystal structure of S.mutans FtsZ,revealing a unique lateral interface.Through protein polymerization and GTPase activity assay,we experimentally demonstrated that the mutation of Arg68 on this lateral interface significantly reduced the functional activity of FtsZ in an acidic environment.The phenotype assay and rat caries model further showed that the mutation of Arg68 effectively inhibited the acid resistance of S.mutans and the occurrence and progress of dental caries in vivo.By employing a molecular dynamics simulation analysis,we conclude that the mutation of Arg68 disrupts the conformation change necessary for SmFtsZ polymerization under acidic conditions.Our study proposes a novel mechanism to maintain FtsZ function in bacteria and could be a potential target for antimicrobial drugs to inhibit the growth of S.mutans in acidic environments.
基金financially supported and funded by the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University(IMSIU)(No.IMSIU-DDRSP2503)。
文摘Functionally graded cellular structures(FGCSs)have a multitude of applications to a wide range of industries.Utilising the ever-progressing technology of additive manufacturing(AM),FGCSs can be applied to control material grading and achieve the desired mechanical properties.The current study explores the design and optimisation of FGCSs for AM,with a focus on improving the compression and impact performance of below knee(BK)prosthetic limbs made of thermoplastic polyurethane(TPU).A multiscale research methodology integrating topology optimization(TO),finite element analysis(FEA),and design of experiments(Do E)was adopted to optimise lattice structures in terms of stiffness and lightweight properties.Two-unit cell designs were considered in the study:Schwarz P gyroid and body-centered cubic(BCC).Response surface methodology(RSM)was implemented to analyse the effect of minimum and maximum cell wall thickness,cell size,and unit cell type on the mechanical performance of TPU FGCS structures.The results indicated that a Schwarz P FGCS structure with cell size,minimum and maximum cell wall thickness of 6,0.9 and 2.8 mm,respectively,could be optimal for a compromise between performance and weight.In this optimized case,stiffness and volume fraction values of 684 N/mm and 0.64 were obtained,respectively.The study also presents a proof-of-concept design for a BK prosthetic damper,highlighting the potential of FGCSs to enhance patient comfort,reduce manufacturing costs,and enable personalised designs through 3D scanning and AM.The obtained results could be a step forward towards the incorporation of AM technologies in prosthetics,offering a pathway to lightweight,cost-effective,and functionally tailored solutions.
基金Supported by Natural Science Foundation of China (100775061, 10505016, 10575119)CAS Knowledge Innovation Project(KJCX-SYW-N02)+1 种基金Major State Basic Research Developing Program of China (2007CB815004)Natural Science Foundationof Hebei Province in China (A2005000535, 103143)
文摘Extended quark distribution functions are presented obtained by fitting a large amount of experimental data of the l-A DIS process on the basis of an improved nuclear density model. The experimental data of l-A DIS processes with A≥ 3 in the region 0.0010 ≤ x ≤ 0.9500 are quite satisfactorily described by using the extended formulae. Our knowledge of the influence of nuclear matter on the quark distributions is deepened.
基金This work was supported by the National Natural Science Foundation of China(31772042)Ramóny Cajal grant(RYC2020-030365-I)+1 种基金Xunta de Galicia for supporting the program(Excelencia-ED431F2022/01)the Key Research&Development Program of Zhejiang Province(2021C02015).
文摘Cuticular wax plays a major role in the growth and storage of plant fruits.The cuticular wax coating,which covers the outermost layer of a fruit’s epidermal cells,is insoluble in water.Cuticular wax is mainly composed of very long-chain fatty acids(VLCFAs);their derivatives,including esters,primary alcohols,secondary alcohols,aldehydes,and ketones;and triterpenoids.This complex mixture of lipids is probably biosynthesized in the epidermal cells of most plants and exuded onto the surface.Cuticular wax not only makes the fruit less susceptible to microbial infection but also reduces mechanical damage to the fruit,thereby maintaining the fruit’s commodity value.To date,research has mostly focused on the changes,function,and regulation of fruit wax before harvest,while ignoring the changes and functions of wax in fruit storage.This paper reviews on the composition,structure,and metabolic regulation of cuticular wax in fruits.It also focuses on postharvest factors affecting wax composition,such as storage temperature,relative humidity(RH),gas atmosphere,and as exogenous hormones;and the effects of wax on fruit postharvest quality,including water dispersion,fruit softening,physiological disorders,and disease resistance.These summaries may be of assistance in better understanding the changes in cuticular wax in postharvest fruit and the resulting effects on fruit quality.
基金supported by the Innovative Research Group Project of the National Natural Science Foundation of China(T2121004)Key Programme(52235007)National Outstanding Youth Foundation of China(52325504).
文摘Hydrogel scaffolds have numerous potential applications in the tissue engineering field.However,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and high mechanical properties.Inspired by Chinese ramen,we propose a universal fabricating method(printing-P,training-T,cross-linking-C,PTC&PCT)for tough hydrogel scaffolds to fill this gap.First,3D printing fabricates a hydrogel scaffold with desired structures(P).Then,the scaffold could have extraordinarily high mechanical properties and functional surface structure by cycle mechanical training with salting-out assistance(T).Finally,the training results are fixed by photo-cross-linking processing(C).The tough gelatin hydrogel scaffolds exhibit excellent tensile strength of 6.66 MPa(622-fold untreated)and have excellent biocompatibility.Furthermore,this scaffold possesses functional surface structures from nanometer to micron to millimeter,which can efficiently induce directional cell growth.Interestingly,this strategy can produce bionic human tissue with mechanical properties of 10 kPa-10 MPa by changing the type of salt,and many hydrogels,such as gelatin and silk,could be improved with PTC or PCT strategies.Animal experiments show that this scaffold can effectively promote the new generation of muscle fibers,blood vessels,and nerves within 4 weeks,prompting the rapid regeneration of large-volume muscle loss injuries.
文摘The development of the socialist market economy demands the furtherintensification of the reform of the management operating system (MOS)of the state-owned assets, the strengthening of the efficiency in the man-agement of state-owned assets,and the improvement of the operating bene-
文摘With the verification of the State Organization Establishment Committee and the approval of the State Council, the CAS is now an institutional organization under the direct supervision of the State Council. It is both the highest academic institution and the most comprehensive research center in natural sciences in China.
基金supported by the National Natural Science Foundation of China(Nos.52072127,52201297,U21A2055,and U22A20160)the China Postdoctoral Science Foundation(No.2022M711200)the Royal Society(No.IEC/NSFC/191344)(UK).
文摘Mimicking the electric microenvironment of natural tissue is a promising strategy for developing biomedical implants. However, current research has not taken biomimetic electrical functional units into consideration when designing biomedical implants. In this research, ordered structures with Schottky heterojunction functional unit (OSSH) were constructed on titanium implant surfaces for bone regeneration regulation. The Schottky heterojunction functional unit is composed of periodically distributed titanium microdomain and titanium oxide microdomain with different carrier densities and surface potentials. The OSSH regulates the M2-type polarization of macrophages to a regenerative immune response by activating the PI3K-AKT-mTOR signal pathway and further promotes osteogenic differentiation of rat bone marrow mesenchymal stem cells. This work provides fundamental insights into the biological effects driven by the Schottky heterojunction functional units that can electrically modulate osteogenesis.
文摘Based on a simple nonrelativistic constituent quark model, the nucleon structure function F<SUB>2</SUB> in the resonance region is estimated by taking the contributions from low-lying nucleon resonances into account. Calculated results are employed to study quark-hardon duality in the nucleon electron scattering process by comparing them to the scaling behavior from the data in deep inelastic scattering region.
文摘By employing the parametrization form of the nucleon spin structure functionin the resonance region, which includes the contributions of the resonance peaks and of nonresonancebackground, we study Bloom—Oilman quark-hadron duality of g_1 both in the inelastic resonanceregion and elastic one.
文摘The aging process is an inexorable fact throughout our lives and is considered a major factor in develo ping neurological dysfunctions associated with cognitive,emotional,and motor impairments.Aging-associated neurodegenerative diseases are characterized by the progressive loss of neuronal structure and function.
基金supported by the Natural Science Foundation of Beijing,China (Grant No. 4092005)the National High Technology Research and Development Program of China (Grant No. 2009AA032704)the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20091103110006)
文摘The evaluation of thermal resistance constitution for packaged A1GaN/GaN high electron mobility transistor （HEMT） by structure function method is proposed in this paper. The evaluation is based on the transient heating measurement of the A1GaN/GaN HEMT by pulsed electrical temperature sensitive parameter method. The extracted chip-level and package-level thermal resistances of the packaged multi-finger A1GaN/GaN HEMT with 400μm SiC substrate are 22.5 K/W and 7.2 K/W respectively, which provides a non-invasive method to evaluate the chip-level thermal resistance of packaged A1GaN/GaN HEMTs. It is also experimentally proved that the extraction of the chip- level thermal resistance by this proposed method is not influenced by package form of the tested device and temperature boundary condition of measurement stage.
