In this paper, a novel approach is proposed for denoising of Chinese calligraphy tablet documents. The method includes two phases: First, a partial differential equations (PDE) based the total variation model and Otsu...In this paper, a novel approach is proposed for denoising of Chinese calligraphy tablet documents. The method includes two phases: First, a partial differential equations (PDE) based the total variation model and Otsu thresholding method are used to preprocess the calligraphy document image. Second, a new method based on run-length statistics and structure charac- teristics of Chinese characters is proposed to remove some random and ant-like noises. This includes the optimal threshold se- lection from histogram of run-length probability density, and improved Hough transform algorithm for line shape noise detection and removal. Examples are given in the paper to demonstrate the proposed method.展开更多
Many types of buildings have been widely constructed in the vicinity of subway lines in China.Normal life and business activities are hampered by excessive subway-induced vibrations.This study aims to determine the in...Many types of buildings have been widely constructed in the vicinity of subway lines in China.Normal life and business activities are hampered by excessive subway-induced vibrations.This study aims to determine the influence of structure characteristics on structure-borne vibrations,generally based on experimental results.Vibration measurements were performed in four typical sites in Wuxi,China,involving over-track buildings,along-track buildings,frame structure buildings and a masonry building.Special structure designs like structure transfer floor were also included.Then,the captured data was analyzed in the time domain and the frequency domain.Furthermore,the influence of building location,structure type and structure layout was investigated.Finally,vibrations were evaluated with ISO and Chinese criteria and structure optimization for vibration attenuation was proposed.It is found that over-track buildings are more severely affected than along-track buildings.Higher frequency contents(20‒60 Hz)in over-track buildings and lower frequency contents(0‒10 Hz)in along-track buildings should be seriously considered in vibration control.Weaker structure member joints and lower material strength would be beneficial to over-track buildings while the inverse situation would be beneficial to along-track buildings.The application of structure transfer floor‒generally stiffer structure members and structure discontinuity‒is also beneficial.展开更多
The structure characteristics and adhesive property of humic substance(HS) extracted with different methods were mainly studied by terms of elementary analysis,visible spectrum,FT-IR spectroscopy,viscosity,adsorption ...The structure characteristics and adhesive property of humic substance(HS) extracted with different methods were mainly studied by terms of elementary analysis,visible spectrum,FT-IR spectroscopy,viscosity,adsorption and pelletizing experiments.The results show that HSs extracted with new method(HS-a) own higher degree of aromatization and polymerization,larger relative molecular mass and more polar functional groups than HS extracted with usual method(HS-b).The viscosity of HS-b is about 30-40 mPa·s lower than that of HS-a.The maximum adsorption amounts of HS-a and HS-b onto iron concentrates are 9.11 mg/g and 8.08 mg/g,respectively.Meanwhile,HS-a has a better performance than HS-b in the practical application for pelletizing of iron concentrates.The difference in agglomeration behaviors with iron concentrates lies in the differences of the structure characteristics of HSs.With higher content of polar functional groups,larger relative molecular mass and viscosity of HSs,the agglomeration behavior is improved.展开更多
By adding zeolite aggregate with good adsorption properties,different mix ratios of added zeolite pervious concrete(ZPC)were designed to compare the water purification effect of ordinary pervious concrete and water pu...By adding zeolite aggregate with good adsorption properties,different mix ratios of added zeolite pervious concrete(ZPC)were designed to compare the water purification effect of ordinary pervious concrete and water purification tests that were conducted.The pore characteristics of the pervious concrete were identified using three-dimensional reconstruction software and the relationship between pore structure and water purification performance was quantified by gray entropy correlation analysis.The results showed that the purification efficiency of zeolite-doped pervious concrete was 17.6%-22.3%higher than that of ordinary pervious concrete.The characteristic parameters of the pore structure of permeable concrete,i.e.planar porosity and tortuosity,were determined using three-dimensional reconstruction software.The correlation between the degree of tortuosity and the removal rate reached more than 0.90,indicating that the internal pore structure of pervious concrete has a good correlation with the water purification performance.展开更多
The basin marginal fault system is the key to understand the formation and evolution of Songliao Basin.In order to investigate the influence of marginal fault system on the structural evolution of Songliao Basin,a com...The basin marginal fault system is the key to understand the formation and evolution of Songliao Basin.In order to investigate the influence of marginal fault system on the structural evolution of Songliao Basin,a comprehensive study was conducted on Shiling Town and Zhuanshanhu area of Yehe Town in Siping City of Jilin Province,where is the southeastern margin of the Songliao Basin and there are a series of well-exposed fault,fold and intrusive bodies belonging to the main marginal fault system of the Songliao Basin known as the Jiamusi-Yitong(Jia-Yi)fault zone.Through profile measurement and field investigation,samples with various lithologies and distinctive features were collected.Detailed field and laboratory works include component and microstructure analysis of these samples,rock-rock contact analysis,main strike measurement and statistics analysis.These data reveal the structural characteristics of the fold,fault and intrusive bodies in the study area.The research results show that the folds are distributed in the Mesozoic strata near the main fault of the eastern branch of the Jia-Yi fault zone,and the folded strata involve the Cretaceous Denglouku and Quantou formations.In addition,the section is dominated by high-angle strikeslip thrust faults.Light-colored veins and dark-colored veins are extensively distributed in the exposed granites.Statistical analysis of joint and fault attitudes in the study area reveals a right-lateral strike-sliping along the main fault.The large-scale right-lateral strike-slip and thrust fault system in Shiling Town occurred in right-lateral transpressive stage in Late Cretaceous.Based on the results above,tectonic evolution sequence in Shiling section of the Jia-Yi fault zone during the Mesozoic can be divided into five stages:Middle Jurassic left-lateral ductile strike-slip stage,Late Jurassic compression stage,Early Cretaceous tension stage,Early Cretaceous extension stage and Late Cretaceous right-lateral transpressive stage.These may have important constraint on understanding the Mesozoic evolution of the Songliao Basin.展开更多
Taking the Wangfu fault depression in the Songliao Basin as an example,on the basis of seismic interpretation and drilling data analysis,the distribution of the basement faults was clarified,the fault activity periods...Taking the Wangfu fault depression in the Songliao Basin as an example,on the basis of seismic interpretation and drilling data analysis,the distribution of the basement faults was clarified,the fault activity periods of the coal-bearing formations were determined,and the fault systems were divided.Combined with the coal seam thickness and actual gas indication in logging,the controls of fault systems in the rift basin on the spatial distribution of coal and the occurrence of coal-rock gas were identified.The results show that the Wangfu fault depression is an asymmetrical graben formed under the control of basement reactivated strike-slip T-rupture,and contains coal-bearing formations and five sub-types of fault systems under three types.The horizontal extension strength,vertical activity strength and tectono-sedimentary filling difference of basement faults control vertical stratigraphic sequences,accumulation intensity,and accumulation frequency of coal seam in rift basin.The structural transfer zone formed during the segmented reactivation and growth of the basement faults controls the injection location of steep slope exogenous clasts.The filling effect induced by igneous intrusion accelerates the sediment filling process in the rift lacustrine area.The structural transfer zone and igneous intrusion together determine the preferential accumulation location of coal seams in the plane.The faults reactivated at the basement and newly formed during the rifting phase serve as pathways connecting to the gas source,affecting the enrichment degree of coal-rock gas.The vertical sealing of the faults was evaluated by using shale smear factor(SSF),and the evaluation criterion was established.It is indicated that the SSF is below 1.1 in major coal areas,indicating favorable preservation conditions for coal-rock gas.Based on the influence factors such as fault activity,segmentation and sealing,the coal-rock gas accumulation model of rift basin was established.展开更多
Ganoderma polysaccharides(GPs),derived from various species of the Ganoderma genus,exhibit diverse bioactivities,including immune modulation,anti-tumor effects,and gut microbiota regulation.These properties position G...Ganoderma polysaccharides(GPs),derived from various species of the Ganoderma genus,exhibit diverse bioactivities,including immune modulation,anti-tumor effects,and gut microbiota regulation.These properties position GPs as dual-purpose agents for medicinal and functional food development.This review comprehensively explores the structural complexity of six key GPs and their specific mechanisms of action,such as TLR signaling in immune modulation,apoptosis pathways in anti-tumor activity,and their prebiotic effects on gut microbiota.Additionally,the structure-activity relationships(SARs)of GPs are highlighted to elucidate their biological efficacy.Advances in green extraction techniques,including ultrasonic-assisted and enzymatic methods,are discussed for their roles in enhancing yield and aligning with sustainable production principles.Furthermore,the review addresses biotechnological innovations in polysaccharide biosynthesis,improving production efficiency and making large-scale production feasible.These insights,combined with ongoing research into their bioactivity,provide a solid foundation for developing health-promoting functional food products that incorporate GPs.Furthermore,future research directions are suggested to optimize biosynthesis pathways and fully harness the health benefits of these polysaccharides.展开更多
The Maoping lead–zinc mining area is a significant metal mine site in northeastern Yunnan.In this study,both hydraulic fracturing in situ stress testing and ultrasonic imaging logging were first carried out in the mi...The Maoping lead–zinc mining area is a significant metal mine site in northeastern Yunnan.In this study,both hydraulic fracturing in situ stress testing and ultrasonic imaging logging were first carried out in the mining area.Second,930 focal mechanism solutions and 231 sets of stress data near the mining area were collected.Then,the variations in the type of in situ stress field,the magnitude of in situ stress,the direction of horizontal principal stress,and the ratio of lateral pressure were analyzed to characterize the distribution of the in situ stress field.On this basis,a new method using borehole breakouts and drilling-induced fractures was proposed to determine the stress direction.Finally,the evolution of the mechanical properties of dolomite with burial depth was analyzed and the influence of rock mechanical properties on the distributions of the in situ stress field was explored.The results show that the in situ stress in the mining area isσ_(H)>σ_(V)>σ_(h),indicating a strike–slip stress state.The in situ stress is high in magnitude,and its value increases with burial depth.The maximum and minimum horizontal lateral stress coefficients are stabilized at approximately 1.22 and 0.73,respectively.The direction of the maximum horizontal principal stress is NW,mainly ranging from N58.44°W to N59.70°W.The stress field inferred from the focal mechanism solution is in good agreement with the test results.The proportion of structural planes with dip angles between 30°and 75°exceeds 80%,and the dip direction of the structural planes is mainly NW to NWW.The line density of structural planes shows high density in shallow areas and low density in deep areas.More energy tends to be accumulated in rocks with higher elastic modulus and strength,leading to higher in situ stress levels.These findings are of significant reference for mine tunnel layout,support design optimization,and disaster prevention.展开更多
In this paper, based on in-situ observational data of the Coordinated Enhanced Observing Period （CEOP） Asia-Australia Monsoon Project （CAMP） on the Tibetan＇Plateau （CAMP-Tibet）, structure of the Atmospheric Bou...In this paper, based on in-situ observational data of the Coordinated Enhanced Observing Period （CEOP） Asia-Australia Monsoon Project （CAMP） on the Tibetan＇Plateau （CAMP-Tibet）, structure of the Atmospheric Boundary Layer （ABL） was preliminarily studied during the dry and rainy seasons. The main results show： （a） Diurnal variation of the ABL is obvious over the northern Tibetan Plateau area. The height of the ABL is different with the season change, which ranges from 2,211 m to 4,430 m during the pre-monsoon season and from 1,006 m to 2,212 m during the monsoon season. The ABL height is higher during the dry period than during the rainyigeriod. （b） The humidity is lower during the dry period than during the rainy period, and there are reverse humidity during both periods. （c） Horizontal wind direction is mostly west during the dry period, east under the height of 2,500 m and west above the height of 2,500 m during the rainy period. The wind speed is low during both the rainy and dry periods in the lower ABL layer. The wind speed is stronger within the upper ABL during the dry period than dtn-ing the rainy period.展开更多
Dy^(3+) and Lu^(3+) co-doped CaLaGa_(3)O_(7) phosphors were prepared via high-temperature solid-phase reaction.The electronic structures of LuxCaLa_(0.98-x)Ga_(3)O_(7) were investigated by the first-principles calcula...Dy^(3+) and Lu^(3+) co-doped CaLaGa_(3)O_(7) phosphors were prepared via high-temperature solid-phase reaction.The electronic structures of LuxCaLa_(0.98-x)Ga_(3)O_(7) were investigated by the first-principles calculations.The influence of Lu^(3+) on yellow light emission was studied using X-ray diffraction(XRD)and photoluminescence(PL) measurements.The XRD results indicate that compared to Dy^(3+):CaLaGa_(3)O_(7),the cell parameters of Dy^(3+):LuCaLaGa_(3)O_(7) tend to decrease,which is due to the smaller radius of Lu^(3+).When pumped by blue GaN laser diode(LD),the emission peaks of phosphors with different Lu^(3+)doping concentrations in the visible region are similar,with the strongest peak at 574 nm in the yellow light region,which is sensitive to human eyes.The optimal doping concentration of Lu^(3+) is confirmed to be1 at%,when all emission spectra and measured fluorescence lifetimes are taken into account.Moreover,the optimal phosphor composition Dy^(3+):Lu_(x)CaLa_(0.98-x)Ga_(3)O_(7)(x=0.01) has an internal quantum efficiency(IQE) of 46.94% and an external quantum efficiency(EQE) of 15.19%.Most notably,the prepared phosphor demonstrates excellent thermal stability and a high activation energy(0.203 eV).In addition,the International Illumination Commission color coordinates of the Dy^(3+):LuxCaLa_(0.98-x)Ga_(3)O_(7) phosphors are in the yellow light area.The above analysis indicates that the Dy^(3+):LuxCaLa_(0.98-x)Ga_(3)O_(7)(x=0.001)phosphor has promising application prospects in yellow light-emitting devices.展开更多
The characteristics of seismogenic structures are an important basis for delineating the potential seismic source areas and determining the annual occurrence rate of earthquakes. The potential seismic source area does...The characteristics of seismogenic structures are an important basis for delineating the potential seismic source areas and determining the annual occurrence rate of earthquakes. The potential seismic source area does not only have the intension that “this area has the possibility for destructive earthquakes to occur in the future" but also means that earthquakes of high magnitude interval have the characteristics of similar recurrence. When determining the seismic activity parameters of a statistical unit, some active tectonic blocks in the unit may have different background earthquakes. In order to better reflect the heterogeneity in space of seismic activities, it is necessary to divide the potential seismic source areas into three orders. By analyzing the recurrence characteristics of earthquakes of high magnitude interval in the potential source area and calculating the occurrence probability of earthquakes of high magnitude interval in the potential seismic source area in the time window for prediction, the average annual occurrence rate of earthquakes can be obtained by the method of probability equivalent conversion in the time window for prediction. This would be helpful for considering the recurrence characteristics of strong earthquakes in potential source areas within the framework of seismic risk analysis of China. Besides, the insufficient frequency of characteristic earthquakes of the next high magnitude interval in the potential source area and the heterogeneity of strong earthquakes on seismogenic structures are analyzed to see their application in seismic risk analysis.展开更多
This study selected the Sino-US route data from the top 30 global container liner companies between December 1,2019,and December 29,2019,as the data source utilizing the complex network research methodology.It constru...This study selected the Sino-US route data from the top 30 global container liner companies between December 1,2019,and December 29,2019,as the data source utilizing the complex network research methodology.It constructs a Sino-US container shipping network through voyage weighting and analyzes the essential structural characteristics to explore the network’s complex structural fea-tures.The network’s evolution is examined from three perspectives,namely,time,space,and event influence,aiming to comprehens-ively explore the network’s evolution mechanism.The results revealed that:1)the weighted Sino-US container shipping network exhib-its small-world and scale-free properties.Key hub ports in the United States include NEW YORK NY,SAVANNAH GA,LOS ANGELES CA,and OAKLAND CA,whereas SHANGHAI serving as the hub port in China.The geographical distribution of these hub ports is uneven.2)Concerning the evolution of the weighted Sino-US container shipping network,from a temporal perspective,the evolution of the regional structure of the entire Sino-US region and the Inland United States is in a stage of radiative expansion and de-velopment,with a need for further enhancement in competitiveness and development speed.The evolution of the regional structure of southern China and Europe is transitioning from the stage of radiative expansion and development to an advanced equilibrium stage.The shipping development in Northern China,the Western and Eastern United States,and Asia is undergoing significant changes but faces challenges of fierce competition and imbalances.From a spatial perspective,the rationality and effectiveness of the improved weighted Barrat-Barthelemy-Vespignani(BBV)model are confirmed through theoretical derivation.The applicability of the improved evolution model is verified by simulating the evolution of the weighted Sino-US container shipping network.From an event impact per-spective,the Corona Virus Disease 2019(COVID-19)pandemic has not fundamentally affected the spatial pattern of the weighted Sino-US container shipping network but has significantly impacted the network’s connectivity.The network lacks sufficient resilience and stability in emergency situations.3)Based on the analysis of the structural characteristics and evolution of the weighted Sino-US con-tainer shipping network,recommendations for network development are proposed from three aspects:emphasizing the development of hub ports,focusing on the balanced development of the network,and optimizing the layout of Chinese ports.展开更多
In this study,on the basis of absolute first-arrival times of 84756 P-and S-waves from 6085 earthquakes recorded at 56 fixed stations in Yibin and surrounding areas in China from January 2009 to January 2019,focal par...In this study,on the basis of absolute first-arrival times of 84756 P-and S-waves from 6085 earthquakes recorded at 56 fixed stations in Yibin and surrounding areas in China from January 2009 to January 2019,focal parameters and three-dimensional(3 D)body-wave high-resolution velocity structures at depths of 0–30 km were retrieved by double-difference tomography.Results show that there is a good correspondence between the spatial distribution of the relocated earthquakes and velocity structures,which were concentrated mainly in the high-velocity-anomaly region or edge of high-velocity region.Velocity structure of P-and S-waves in the Yibin area clearly shows lateral inhomogeneity.The distribution characteristics of the P-and S-waves near the surface are closely related to the geomorphology and geologic structure.The low-velocity anomaly appears at the depth of 15–25 km,which is affected by the lower crust current.The Junlian–Gongxian and Gongxian–Changning earthquake areas,which are the two most earthquake-prone areas in the Yibin region,clearly differ in earthquake distribution and tectonic characteristics.We analyzed the structural characteristics of the Junlian–Gongxian and Gongxian–Changning earthquake areas on the basis of the 3 D bodywave velocity structures in the Yibin region.We found that although most seismicity in the Yibin area is caused by fluid injection,the spatial position of seismicity is controlled by the velocity structures of the middle and upper crust and local geologic structure.Fine-scale 3 D velocity structures in the Yibin area provide important local reference information for further understanding the crustal medium,seismogenic structure,and seismicity.展开更多
The Baoshan Cu-Pb-Zn polymetallic deposit is lied in the central Nanling mineralization zone,and belongs to the junction area of the Chenzhou-Linwu fault zone and the Leiyang-Linwu fault zone.It is a significant part ...The Baoshan Cu-Pb-Zn polymetallic deposit is lied in the central Nanling mineralization zone,and belongs to the junction area of the Chenzhou-Linwu fault zone and the Leiyang-Linwu fault zone.It is a significant part of Nanling polymetallic deposit belt.The outcropping stratas consist of upper Devonian Shetianqiao,Xikuangshan Formation,Lower Carboniferous Menggong’ao,Shidengzi,Ceshui,and Zimenqiao Formation.Igneous rocks in the Baoshan ore area mainly comprise granodiorite porphyry.Furthermore,the radio isotopic age ranges from 123 Ma to 183 Ma,belonging to the early to middle Yanshanian.展开更多
Various characteristic structures in typical magnesium alloys,including dislocation cells,substructures and twins,have an important influence on the dynamic recrystallization behavior,and the DRX(dynamic recrystalliza...Various characteristic structures in typical magnesium alloys,including dislocation cells,substructures and twins,have an important influence on the dynamic recrystallization behavior,and the DRX(dynamic recrystallization)behavior is closely related to the grain refinement and texture weakening of the hot deformed structure.Therefore,this study reveals the influence of the above characteristic structures on the dynamic recrystallization behavior of magnesium alloys,which have great significance for regulating the high-performance hot deformed microstructure of magnesium alloys and optimizing the macro mechanical properties.In this study,continuous variable channel direct extrusion(CVCDE)magnesium alloy was prepared by CVCDE,and its macro mechanical properties including hardness and uniaxial tension were characterized.The thermoplastic deformation behavior and texture evolution of magnesium alloy with characteristic structure were analyzed by electron back-scattering diffraction technology.It is found that the dislocation recombination was realized by deformation mechanism(slip,climb and cross slip),the formation of grain substructure in coarse grains and the induction of recrystallization by twins promote the recrystallization behavior in hot deformed structures more adequate,which effectively improves the degree of microstructure refinement and deformation uniformity.展开更多
It was proved that velocity-dependent infinitesima l symmetry transformations of nonholonomic systems have a characteristic functio nal structure, which could be formulated by means of an auxiliary symmetry tra nsform...It was proved that velocity-dependent infinitesima l symmetry transformations of nonholonomic systems have a characteristic functio nal structure, which could be formulated by means of an auxiliary symmetry tra nsformation function and is manifestly dependent upon constants of motion of th e system. An example was given to illustrate the applicability of the results.展开更多
It is known that structural stiffness and strength distributions have an important role in the seismic response of buildings. The effect of using different code-specified lateral load patterns on the seismic performan...It is known that structural stiffness and strength distributions have an important role in the seismic response of buildings. The effect of using different code-specified lateral load patterns on the seismic performance of fixed-base buildings has been investigated by researchers during the past two decades. However, no investigation has yet been carried out for the case of soil-structure systems. In the present study, through intensive parametric analyses of 21,600 linear and nonlinear MDOF systems and considering five different shear strength and stiffness distribution patterns, including three code-specified patterns as well as uniform and concentric patterns subjected to a group of earthquakes recorded on alluvium and soft soils, the effect of structural characteristics distribution on the strength demand and ductility reduction factor of MDOF fixed-base and soil-structure systems are parametrically investigated. The results of this study show that depending on the level of inelasticity, soil flexibility and number of degrees-of-freedoms (DOFs), structural characteristics distribution can significantly affect the strength demand and ductility reduction factor of MDOF systems. It is also found that at high levels of inelasticity, the ductility reduction factor of low-rise MDOF soil-structure systems could be significantly less than that of fixed-base structures and the reduction is less pronounced as the number of stories increases.展开更多
The linear dispersion relation of a trapezoidally corrugated slow wave structure （TCSWS） is analyzed and presented. The size parameters of the TCSWS are chosen in such a way that they operate in the x-band frequency...The linear dispersion relation of a trapezoidally corrugated slow wave structure （TCSWS） is analyzed and presented. The size parameters of the TCSWS are chosen in such a way that they operate in the x-band frequency range. The dispersion relation is solved by utilizing the Rayleigh-Fourier method by expressing the radial function in terms of the Fourier series. A highly accurate synthetic technique is also applied to determine the complete dispersion characteristics from experimentally measured resonances （cold test）. Periodic structures resonate at specific frequencies when the terminals are shorted numerical calculation, synthetic technique and cold appropriately. The dispersion characteristics obtained from test are compared, and an excellent agreement is achieved.展开更多
Doxorubicin(DOX)is a widely employed tumor therapy,yet its substantial toxic side effects pose a considerable challenge.Bletilla striata has demonstrated efficacy in preventing and treating these toxic side effects in...Doxorubicin(DOX)is a widely employed tumor therapy,yet its substantial toxic side effects pose a considerable challenge.Bletilla striata has demonstrated efficacy in preventing and treating these toxic side effects in clinical practice,with polysaccharides identified as the principal active component.In the present study,16 fractions of B.striata polysaccharides(BsPs)were extracted using diverse methods,including hot-water extraction(HWE),ultrasonic-assisted extraction(UAE),enzyme-assisted extraction(EAE),dilute acid-water extraction(ACWE),and dilute alkali-water extraction(ALWE).These extractions were subsequently precipitated at final ethanol concentrations of 80%and 95%,respectively.The investigation encompassed yields,total carbohydrate content(TCC),total protein content(TPC),preliminary structural properties,and anti-DOX myocardial cytotoxic activity.Results indicated that the extraction method significantly influenced the physicochemical properties,associated functional properties,and anti-DOX myocardial cytotoxic activity of BsPs.HWE and UAE yielded higher BsPs quantities.The relative molecular weight(RMW)distribution of BsPs differed notably between HWE or UAE,EAE,ACWE,and ALWE.The RMW of primary BsPs obtained from HWE and UAE(1.9×10^(7)-1.7×10^(7) Da)exceeded that from EAE(7.5×10^(3)-2.8×10^(4) Da)and ALWE(5.1×10^(4)-1.7×10^(4) Da),with smaller molecular weights primarily precipitated by higher ethanol concentrations.BsPs were composed of Man and Glu,with partial fractions containing small amounts of Gal or Ara,displaying varying molar ratios.Notably,BsPs from ACWE exhibited the most significant structural differences,lacking 1,4-α-D-Glcp and a triple-helical structure.Furthermore,BsPs obtained from HWE,UAE,and EAE demonstrated heightened anti-DOX myocardial cytotoxic activity compared to other methods.This study underscored the influence of extraction methods on BsPs’structure and myocardial protective activity,offering a foundation for exploring structural diversity and employing specific extraction methods to extract polysaccharides with robust myocardial protective properties efficiently.展开更多
Au/n-Si （MS） structures with a high dielectric interlayer （0.03 graphene-doped PVA） are fabricated to investigate the illumination and voltage effects on electrical and dielectric properties by using capacitance-v...Au/n-Si （MS） structures with a high dielectric interlayer （0.03 graphene-doped PVA） are fabricated to investigate the illumination and voltage effects on electrical and dielectric properties by using capacitance-voltage （C-V） and conductance-voltage （G/w-V） measurements at room temperature and at 1 MHz. Some of the main electrical parameters such as concentration of doping atoms （ND）, barrier height （ ФB（ C - V） ）, depletion layer width （WD） and series resistance （Rs） show fairly large illumination dispersion. The voltage-dependent profile of surface states （Nss） and resistance of the structure （Ri ） are also obtained by using the dark-illumination capacitance （Cdark- Cm） and Nicollian-Brews methods, respectively, For a clear observation of changes in electrical parameters with illumination, the values of ND, WD, ФB（O- V） and Rs are drawn as a function of illumination intensity. The values of ND and WD change almost linearly with illumination intensity. On the other hand, Rs decreases almost exponentially with increasing illumination intensity whereas ФB（C - V） increases. The experimental results suggest that the use of a high dielectric interlayer （0.03 graphene-doped PVA） considerably passivates or reduces the magnitude of the surface states. The large change or dispersion in main electrical parameters can be attributed to generation of electron-hole pairs in the junction under illumination and to a good light absorption. All of these experimental results confirm that the fabricated Au/0.03 graphene-doped PVA/n-Si structure can be used as a photodiode or a capacitor in optoelectronic applications.展开更多
基金Project supported by the National Basic Research Program (973) of China (No. 2002-CB-312101) and the National Natural Science Foundation of China (No. 60773037)
文摘In this paper, a novel approach is proposed for denoising of Chinese calligraphy tablet documents. The method includes two phases: First, a partial differential equations (PDE) based the total variation model and Otsu thresholding method are used to preprocess the calligraphy document image. Second, a new method based on run-length statistics and structure charac- teristics of Chinese characters is proposed to remove some random and ant-like noises. This includes the optimal threshold se- lection from histogram of run-length probability density, and improved Hough transform algorithm for line shape noise detection and removal. Examples are given in the paper to demonstrate the proposed method.
基金National Basic Research Program of China(973 Program)under Grant No.2014CB049101。
文摘Many types of buildings have been widely constructed in the vicinity of subway lines in China.Normal life and business activities are hampered by excessive subway-induced vibrations.This study aims to determine the influence of structure characteristics on structure-borne vibrations,generally based on experimental results.Vibration measurements were performed in four typical sites in Wuxi,China,involving over-track buildings,along-track buildings,frame structure buildings and a masonry building.Special structure designs like structure transfer floor were also included.Then,the captured data was analyzed in the time domain and the frequency domain.Furthermore,the influence of building location,structure type and structure layout was investigated.Finally,vibrations were evaluated with ISO and Chinese criteria and structure optimization for vibration attenuation was proposed.It is found that over-track buildings are more severely affected than along-track buildings.Higher frequency contents(20‒60 Hz)in over-track buildings and lower frequency contents(0‒10 Hz)in along-track buildings should be seriously considered in vibration control.Weaker structure member joints and lower material strength would be beneficial to over-track buildings while the inverse situation would be beneficial to along-track buildings.The application of structure transfer floor‒generally stiffer structure members and structure discontinuity‒is also beneficial.
基金Project(50725416) supported by the National Science Fund for Distinguished Young Scholars of ChinaProject(50804059) supported by the National Natural Science Foundation of China+1 种基金Project(200805331080) supported by Specialized Research Fund for the Doctoral Program of Higher Education of ChinaProject supported by the Graduate Degree Thesis Innovation Foundation of Central South University,China
文摘The structure characteristics and adhesive property of humic substance(HS) extracted with different methods were mainly studied by terms of elementary analysis,visible spectrum,FT-IR spectroscopy,viscosity,adsorption and pelletizing experiments.The results show that HSs extracted with new method(HS-a) own higher degree of aromatization and polymerization,larger relative molecular mass and more polar functional groups than HS extracted with usual method(HS-b).The viscosity of HS-b is about 30-40 mPa·s lower than that of HS-a.The maximum adsorption amounts of HS-a and HS-b onto iron concentrates are 9.11 mg/g and 8.08 mg/g,respectively.Meanwhile,HS-a has a better performance than HS-b in the practical application for pelletizing of iron concentrates.The difference in agglomeration behaviors with iron concentrates lies in the differences of the structure characteristics of HSs.With higher content of polar functional groups,larger relative molecular mass and viscosity of HSs,the agglomeration behavior is improved.
基金Hunan Provincial Department of Water Resources:Research on Formula Optimization and Performance Evaluation System of Ecological Concrete for River Water Quality Purification Based on the Dual Carbon Goal(Project No.:XSKJ2024064-44)。
文摘By adding zeolite aggregate with good adsorption properties,different mix ratios of added zeolite pervious concrete(ZPC)were designed to compare the water purification effect of ordinary pervious concrete and water purification tests that were conducted.The pore characteristics of the pervious concrete were identified using three-dimensional reconstruction software and the relationship between pore structure and water purification performance was quantified by gray entropy correlation analysis.The results showed that the purification efficiency of zeolite-doped pervious concrete was 17.6%-22.3%higher than that of ordinary pervious concrete.The characteristic parameters of the pore structure of permeable concrete,i.e.planar porosity and tortuosity,were determined using three-dimensional reconstruction software.The correlation between the degree of tortuosity and the removal rate reached more than 0.90,indicating that the internal pore structure of pervious concrete has a good correlation with the water purification performance.
基金Supported by the Key Research and Development Program of Heilongjiang Province(No.JD22A022)the Natural Science Foundation of Heilongjiang Province of China(Nos.LH2022D013,LH2023D005)the Support Project for Young Talents in Local Universities in Heilongjiang Province(No.14011202101).
文摘The basin marginal fault system is the key to understand the formation and evolution of Songliao Basin.In order to investigate the influence of marginal fault system on the structural evolution of Songliao Basin,a comprehensive study was conducted on Shiling Town and Zhuanshanhu area of Yehe Town in Siping City of Jilin Province,where is the southeastern margin of the Songliao Basin and there are a series of well-exposed fault,fold and intrusive bodies belonging to the main marginal fault system of the Songliao Basin known as the Jiamusi-Yitong(Jia-Yi)fault zone.Through profile measurement and field investigation,samples with various lithologies and distinctive features were collected.Detailed field and laboratory works include component and microstructure analysis of these samples,rock-rock contact analysis,main strike measurement and statistics analysis.These data reveal the structural characteristics of the fold,fault and intrusive bodies in the study area.The research results show that the folds are distributed in the Mesozoic strata near the main fault of the eastern branch of the Jia-Yi fault zone,and the folded strata involve the Cretaceous Denglouku and Quantou formations.In addition,the section is dominated by high-angle strikeslip thrust faults.Light-colored veins and dark-colored veins are extensively distributed in the exposed granites.Statistical analysis of joint and fault attitudes in the study area reveals a right-lateral strike-sliping along the main fault.The large-scale right-lateral strike-slip and thrust fault system in Shiling Town occurred in right-lateral transpressive stage in Late Cretaceous.Based on the results above,tectonic evolution sequence in Shiling section of the Jia-Yi fault zone during the Mesozoic can be divided into five stages:Middle Jurassic left-lateral ductile strike-slip stage,Late Jurassic compression stage,Early Cretaceous tension stage,Early Cretaceous extension stage and Late Cretaceous right-lateral transpressive stage.These may have important constraint on understanding the Mesozoic evolution of the Songliao Basin.
基金Supported by the National Natural Science Foundation of China(42472190)Chongqing Natural Science Foundation Innovation and Development Joint Fund Project(CSTB2022NSCQ-LZX0020)Chongqing Talent Innovation and Entrepreneurship Leading Talent Project(0255-19230101042)。
文摘Taking the Wangfu fault depression in the Songliao Basin as an example,on the basis of seismic interpretation and drilling data analysis,the distribution of the basement faults was clarified,the fault activity periods of the coal-bearing formations were determined,and the fault systems were divided.Combined with the coal seam thickness and actual gas indication in logging,the controls of fault systems in the rift basin on the spatial distribution of coal and the occurrence of coal-rock gas were identified.The results show that the Wangfu fault depression is an asymmetrical graben formed under the control of basement reactivated strike-slip T-rupture,and contains coal-bearing formations and five sub-types of fault systems under three types.The horizontal extension strength,vertical activity strength and tectono-sedimentary filling difference of basement faults control vertical stratigraphic sequences,accumulation intensity,and accumulation frequency of coal seam in rift basin.The structural transfer zone formed during the segmented reactivation and growth of the basement faults controls the injection location of steep slope exogenous clasts.The filling effect induced by igneous intrusion accelerates the sediment filling process in the rift lacustrine area.The structural transfer zone and igneous intrusion together determine the preferential accumulation location of coal seams in the plane.The faults reactivated at the basement and newly formed during the rifting phase serve as pathways connecting to the gas source,affecting the enrichment degree of coal-rock gas.The vertical sealing of the faults was evaluated by using shale smear factor(SSF),and the evaluation criterion was established.It is indicated that the SSF is below 1.1 in major coal areas,indicating favorable preservation conditions for coal-rock gas.Based on the influence factors such as fault activity,segmentation and sealing,the coal-rock gas accumulation model of rift basin was established.
基金supported by the National Natural Science Foundation of China(Nos.82373762,31872675)Major Special Programe of science and technology of Yunnan(202402AA310032,202305AH340005)+1 种基金the Cooperation Project with DR PLANT Company(2023)the Foundation of the State Key Laboratory of Phytochemistry and Plant Resources in West China(Nos.P2020-KF02,P2022-KF10).
文摘Ganoderma polysaccharides(GPs),derived from various species of the Ganoderma genus,exhibit diverse bioactivities,including immune modulation,anti-tumor effects,and gut microbiota regulation.These properties position GPs as dual-purpose agents for medicinal and functional food development.This review comprehensively explores the structural complexity of six key GPs and their specific mechanisms of action,such as TLR signaling in immune modulation,apoptosis pathways in anti-tumor activity,and their prebiotic effects on gut microbiota.Additionally,the structure-activity relationships(SARs)of GPs are highlighted to elucidate their biological efficacy.Advances in green extraction techniques,including ultrasonic-assisted and enzymatic methods,are discussed for their roles in enhancing yield and aligning with sustainable production principles.Furthermore,the review addresses biotechnological innovations in polysaccharide biosynthesis,improving production efficiency and making large-scale production feasible.These insights,combined with ongoing research into their bioactivity,provide a solid foundation for developing health-promoting functional food products that incorporate GPs.Furthermore,future research directions are suggested to optimize biosynthesis pathways and fully harness the health benefits of these polysaccharides.
基金National Key Research and Development Program of China,Grant/Award Number:2022YFC2904100National Natural Science Foundation of China,Grant/Award Number:5220409Beijing Noval Program,Grant/Award Number:20230484242。
文摘The Maoping lead–zinc mining area is a significant metal mine site in northeastern Yunnan.In this study,both hydraulic fracturing in situ stress testing and ultrasonic imaging logging were first carried out in the mining area.Second,930 focal mechanism solutions and 231 sets of stress data near the mining area were collected.Then,the variations in the type of in situ stress field,the magnitude of in situ stress,the direction of horizontal principal stress,and the ratio of lateral pressure were analyzed to characterize the distribution of the in situ stress field.On this basis,a new method using borehole breakouts and drilling-induced fractures was proposed to determine the stress direction.Finally,the evolution of the mechanical properties of dolomite with burial depth was analyzed and the influence of rock mechanical properties on the distributions of the in situ stress field was explored.The results show that the in situ stress in the mining area isσ_(H)>σ_(V)>σ_(h),indicating a strike–slip stress state.The in situ stress is high in magnitude,and its value increases with burial depth.The maximum and minimum horizontal lateral stress coefficients are stabilized at approximately 1.22 and 0.73,respectively.The direction of the maximum horizontal principal stress is NW,mainly ranging from N58.44°W to N59.70°W.The stress field inferred from the focal mechanism solution is in good agreement with the test results.The proportion of structural planes with dip angles between 30°and 75°exceeds 80%,and the dip direction of the structural planes is mainly NW to NWW.The line density of structural planes shows high density in shallow areas and low density in deep areas.More energy tends to be accumulated in rocks with higher elastic modulus and strength,leading to higher in situ stress levels.These findings are of significant reference for mine tunnel layout,support design optimization,and disaster prevention.
基金under the auspices of the Chinese National Key Programme for Developing Basic Sciences (2010CB951703)the Chinese National Key Programme for Developing Basic Sciences (2005CB422003)the National Natural Science Foundation of China (41175008, 40810059006 and 40675012)
文摘In this paper, based on in-situ observational data of the Coordinated Enhanced Observing Period （CEOP） Asia-Australia Monsoon Project （CAMP） on the Tibetan＇Plateau （CAMP-Tibet）, structure of the Atmospheric Boundary Layer （ABL） was preliminarily studied during the dry and rainy seasons. The main results show： （a） Diurnal variation of the ABL is obvious over the northern Tibetan Plateau area. The height of the ABL is different with the season change, which ranges from 2,211 m to 4,430 m during the pre-monsoon season and from 1,006 m to 2,212 m during the monsoon season. The ABL height is higher during the dry period than during the rainyigeriod. （b） The humidity is lower during the dry period than during the rainy period, and there are reverse humidity during both periods. （c） Horizontal wind direction is mostly west during the dry period, east under the height of 2,500 m and west above the height of 2,500 m during the rainy period. The wind speed is low during both the rainy and dry periods in the lower ABL layer. The wind speed is stronger within the upper ABL during the dry period than dtn-ing the rainy period.
基金supported by the Shandong Provincial Natural Science Foundation (ZR2020QE034,ZR2021QF081)National Natural Science Foundation of China (11974304)Anhui Provincial Natural Science Foundation(2008085QA45,2008085QA49)。
文摘Dy^(3+) and Lu^(3+) co-doped CaLaGa_(3)O_(7) phosphors were prepared via high-temperature solid-phase reaction.The electronic structures of LuxCaLa_(0.98-x)Ga_(3)O_(7) were investigated by the first-principles calculations.The influence of Lu^(3+) on yellow light emission was studied using X-ray diffraction(XRD)and photoluminescence(PL) measurements.The XRD results indicate that compared to Dy^(3+):CaLaGa_(3)O_(7),the cell parameters of Dy^(3+):LuCaLaGa_(3)O_(7) tend to decrease,which is due to the smaller radius of Lu^(3+).When pumped by blue GaN laser diode(LD),the emission peaks of phosphors with different Lu^(3+)doping concentrations in the visible region are similar,with the strongest peak at 574 nm in the yellow light region,which is sensitive to human eyes.The optimal doping concentration of Lu^(3+) is confirmed to be1 at%,when all emission spectra and measured fluorescence lifetimes are taken into account.Moreover,the optimal phosphor composition Dy^(3+):Lu_(x)CaLa_(0.98-x)Ga_(3)O_(7)(x=0.01) has an internal quantum efficiency(IQE) of 46.94% and an external quantum efficiency(EQE) of 15.19%.Most notably,the prepared phosphor demonstrates excellent thermal stability and a high activation energy(0.203 eV).In addition,the International Illumination Commission color coordinates of the Dy^(3+):LuxCaLa_(0.98-x)Ga_(3)O_(7) phosphors are in the yellow light area.The above analysis indicates that the Dy^(3+):LuxCaLa_(0.98-x)Ga_(3)O_(7)(x=0.001)phosphor has promising application prospects in yellow light-emitting devices.
文摘The characteristics of seismogenic structures are an important basis for delineating the potential seismic source areas and determining the annual occurrence rate of earthquakes. The potential seismic source area does not only have the intension that “this area has the possibility for destructive earthquakes to occur in the future" but also means that earthquakes of high magnitude interval have the characteristics of similar recurrence. When determining the seismic activity parameters of a statistical unit, some active tectonic blocks in the unit may have different background earthquakes. In order to better reflect the heterogeneity in space of seismic activities, it is necessary to divide the potential seismic source areas into three orders. By analyzing the recurrence characteristics of earthquakes of high magnitude interval in the potential source area and calculating the occurrence probability of earthquakes of high magnitude interval in the potential seismic source area in the time window for prediction, the average annual occurrence rate of earthquakes can be obtained by the method of probability equivalent conversion in the time window for prediction. This would be helpful for considering the recurrence characteristics of strong earthquakes in potential source areas within the framework of seismic risk analysis of China. Besides, the insufficient frequency of characteristic earthquakes of the next high magnitude interval in the potential source area and the heterogeneity of strong earthquakes on seismogenic structures are analyzed to see their application in seismic risk analysis.
基金Under the auspices of National Natural Science Foundation of China(No.41201473,41371975)。
文摘This study selected the Sino-US route data from the top 30 global container liner companies between December 1,2019,and December 29,2019,as the data source utilizing the complex network research methodology.It constructs a Sino-US container shipping network through voyage weighting and analyzes the essential structural characteristics to explore the network’s complex structural fea-tures.The network’s evolution is examined from three perspectives,namely,time,space,and event influence,aiming to comprehens-ively explore the network’s evolution mechanism.The results revealed that:1)the weighted Sino-US container shipping network exhib-its small-world and scale-free properties.Key hub ports in the United States include NEW YORK NY,SAVANNAH GA,LOS ANGELES CA,and OAKLAND CA,whereas SHANGHAI serving as the hub port in China.The geographical distribution of these hub ports is uneven.2)Concerning the evolution of the weighted Sino-US container shipping network,from a temporal perspective,the evolution of the regional structure of the entire Sino-US region and the Inland United States is in a stage of radiative expansion and de-velopment,with a need for further enhancement in competitiveness and development speed.The evolution of the regional structure of southern China and Europe is transitioning from the stage of radiative expansion and development to an advanced equilibrium stage.The shipping development in Northern China,the Western and Eastern United States,and Asia is undergoing significant changes but faces challenges of fierce competition and imbalances.From a spatial perspective,the rationality and effectiveness of the improved weighted Barrat-Barthelemy-Vespignani(BBV)model are confirmed through theoretical derivation.The applicability of the improved evolution model is verified by simulating the evolution of the weighted Sino-US container shipping network.From an event impact per-spective,the Corona Virus Disease 2019(COVID-19)pandemic has not fundamentally affected the spatial pattern of the weighted Sino-US container shipping network but has significantly impacted the network’s connectivity.The network lacks sufficient resilience and stability in emergency situations.3)Based on the analysis of the structural characteristics and evolution of the weighted Sino-US con-tainer shipping network,recommendations for network development are proposed from three aspects:emphasizing the development of hub ports,focusing on the balanced development of the network,and optimizing the layout of Chinese ports.
基金supported by the Research Project of Tianjin Earthquake Agency(No.yb201901)Seismic Regime Tracking Project of CEA(No.2019010127)Combination Project with Monitoring,Prediction and Scientific Research of Earthquake Technology,CEA(No.3JH-201901006)
文摘In this study,on the basis of absolute first-arrival times of 84756 P-and S-waves from 6085 earthquakes recorded at 56 fixed stations in Yibin and surrounding areas in China from January 2009 to January 2019,focal parameters and three-dimensional(3 D)body-wave high-resolution velocity structures at depths of 0–30 km were retrieved by double-difference tomography.Results show that there is a good correspondence between the spatial distribution of the relocated earthquakes and velocity structures,which were concentrated mainly in the high-velocity-anomaly region or edge of high-velocity region.Velocity structure of P-and S-waves in the Yibin area clearly shows lateral inhomogeneity.The distribution characteristics of the P-and S-waves near the surface are closely related to the geomorphology and geologic structure.The low-velocity anomaly appears at the depth of 15–25 km,which is affected by the lower crust current.The Junlian–Gongxian and Gongxian–Changning earthquake areas,which are the two most earthquake-prone areas in the Yibin region,clearly differ in earthquake distribution and tectonic characteristics.We analyzed the structural characteristics of the Junlian–Gongxian and Gongxian–Changning earthquake areas on the basis of the 3 D bodywave velocity structures in the Yibin region.We found that although most seismicity in the Yibin area is caused by fluid injection,the spatial position of seismicity is controlled by the velocity structures of the middle and upper crust and local geologic structure.Fine-scale 3 D velocity structures in the Yibin area provide important local reference information for further understanding the crustal medium,seismogenic structure,and seismicity.
基金Supported by the Program of Superseding Resources Prospecting in Crisis Mines in China(20089927)
文摘The Baoshan Cu-Pb-Zn polymetallic deposit is lied in the central Nanling mineralization zone,and belongs to the junction area of the Chenzhou-Linwu fault zone and the Leiyang-Linwu fault zone.It is a significant part of Nanling polymetallic deposit belt.The outcropping stratas consist of upper Devonian Shetianqiao,Xikuangshan Formation,Lower Carboniferous Menggong’ao,Shidengzi,Ceshui,and Zimenqiao Formation.Igneous rocks in the Baoshan ore area mainly comprise granodiorite porphyry.Furthermore,the radio isotopic age ranges from 123 Ma to 183 Ma,belonging to the early to middle Yanshanian.
基金the Natural Science Foundation of Heilongjiang Province(JQ2022E004).
文摘Various characteristic structures in typical magnesium alloys,including dislocation cells,substructures and twins,have an important influence on the dynamic recrystallization behavior,and the DRX(dynamic recrystallization)behavior is closely related to the grain refinement and texture weakening of the hot deformed structure.Therefore,this study reveals the influence of the above characteristic structures on the dynamic recrystallization behavior of magnesium alloys,which have great significance for regulating the high-performance hot deformed microstructure of magnesium alloys and optimizing the macro mechanical properties.In this study,continuous variable channel direct extrusion(CVCDE)magnesium alloy was prepared by CVCDE,and its macro mechanical properties including hardness and uniaxial tension were characterized.The thermoplastic deformation behavior and texture evolution of magnesium alloy with characteristic structure were analyzed by electron back-scattering diffraction technology.It is found that the dislocation recombination was realized by deformation mechanism(slip,climb and cross slip),the formation of grain substructure in coarse grains and the induction of recrystallization by twins promote the recrystallization behavior in hot deformed structures more adequate,which effectively improves the degree of microstructure refinement and deformation uniformity.
文摘It was proved that velocity-dependent infinitesima l symmetry transformations of nonholonomic systems have a characteristic functio nal structure, which could be formulated by means of an auxiliary symmetry tra nsformation function and is manifestly dependent upon constants of motion of th e system. An example was given to illustrate the applicability of the results.
文摘It is known that structural stiffness and strength distributions have an important role in the seismic response of buildings. The effect of using different code-specified lateral load patterns on the seismic performance of fixed-base buildings has been investigated by researchers during the past two decades. However, no investigation has yet been carried out for the case of soil-structure systems. In the present study, through intensive parametric analyses of 21,600 linear and nonlinear MDOF systems and considering five different shear strength and stiffness distribution patterns, including three code-specified patterns as well as uniform and concentric patterns subjected to a group of earthquakes recorded on alluvium and soft soils, the effect of structural characteristics distribution on the strength demand and ductility reduction factor of MDOF fixed-base and soil-structure systems are parametrically investigated. The results of this study show that depending on the level of inelasticity, soil flexibility and number of degrees-of-freedoms (DOFs), structural characteristics distribution can significantly affect the strength demand and ductility reduction factor of MDOF systems. It is also found that at high levels of inelasticity, the ductility reduction factor of low-rise MDOF soil-structure systems could be significantly less than that of fixed-base structures and the reduction is less pronounced as the number of stories increases.
文摘The linear dispersion relation of a trapezoidally corrugated slow wave structure （TCSWS） is analyzed and presented. The size parameters of the TCSWS are chosen in such a way that they operate in the x-band frequency range. The dispersion relation is solved by utilizing the Rayleigh-Fourier method by expressing the radial function in terms of the Fourier series. A highly accurate synthetic technique is also applied to determine the complete dispersion characteristics from experimentally measured resonances （cold test）. Periodic structures resonate at specific frequencies when the terminals are shorted numerical calculation, synthetic technique and cold appropriately. The dispersion characteristics obtained from test are compared, and an excellent agreement is achieved.
基金Science and Technology Foundation of Guizhou Province(Grant No.QKHJC-ZK[2023]YB524)Science and Technology Plan Project of Guizhou,China(Grant No.QKPTRC[2019]035)+2 种基金Science and Technology Foundation of Guizhou Province(Grant No.QKH[2019]1346)Science and Technology Department of Zunyi city of Guizhou province of China(Grant No.[2020]7)Undergraduate Training Program for Innovation and Entrepreneurship of Zunyi Medical University(Grant No.S202310661248).
文摘Doxorubicin(DOX)is a widely employed tumor therapy,yet its substantial toxic side effects pose a considerable challenge.Bletilla striata has demonstrated efficacy in preventing and treating these toxic side effects in clinical practice,with polysaccharides identified as the principal active component.In the present study,16 fractions of B.striata polysaccharides(BsPs)were extracted using diverse methods,including hot-water extraction(HWE),ultrasonic-assisted extraction(UAE),enzyme-assisted extraction(EAE),dilute acid-water extraction(ACWE),and dilute alkali-water extraction(ALWE).These extractions were subsequently precipitated at final ethanol concentrations of 80%and 95%,respectively.The investigation encompassed yields,total carbohydrate content(TCC),total protein content(TPC),preliminary structural properties,and anti-DOX myocardial cytotoxic activity.Results indicated that the extraction method significantly influenced the physicochemical properties,associated functional properties,and anti-DOX myocardial cytotoxic activity of BsPs.HWE and UAE yielded higher BsPs quantities.The relative molecular weight(RMW)distribution of BsPs differed notably between HWE or UAE,EAE,ACWE,and ALWE.The RMW of primary BsPs obtained from HWE and UAE(1.9×10^(7)-1.7×10^(7) Da)exceeded that from EAE(7.5×10^(3)-2.8×10^(4) Da)and ALWE(5.1×10^(4)-1.7×10^(4) Da),with smaller molecular weights primarily precipitated by higher ethanol concentrations.BsPs were composed of Man and Glu,with partial fractions containing small amounts of Gal or Ara,displaying varying molar ratios.Notably,BsPs from ACWE exhibited the most significant structural differences,lacking 1,4-α-D-Glcp and a triple-helical structure.Furthermore,BsPs obtained from HWE,UAE,and EAE demonstrated heightened anti-DOX myocardial cytotoxic activity compared to other methods.This study underscored the influence of extraction methods on BsPs’structure and myocardial protective activity,offering a foundation for exploring structural diversity and employing specific extraction methods to extract polysaccharides with robust myocardial protective properties efficiently.
文摘Au/n-Si （MS） structures with a high dielectric interlayer （0.03 graphene-doped PVA） are fabricated to investigate the illumination and voltage effects on electrical and dielectric properties by using capacitance-voltage （C-V） and conductance-voltage （G/w-V） measurements at room temperature and at 1 MHz. Some of the main electrical parameters such as concentration of doping atoms （ND）, barrier height （ ФB（ C - V） ）, depletion layer width （WD） and series resistance （Rs） show fairly large illumination dispersion. The voltage-dependent profile of surface states （Nss） and resistance of the structure （Ri ） are also obtained by using the dark-illumination capacitance （Cdark- Cm） and Nicollian-Brews methods, respectively, For a clear observation of changes in electrical parameters with illumination, the values of ND, WD, ФB（O- V） and Rs are drawn as a function of illumination intensity. The values of ND and WD change almost linearly with illumination intensity. On the other hand, Rs decreases almost exponentially with increasing illumination intensity whereas ФB（C - V） increases. The experimental results suggest that the use of a high dielectric interlayer （0.03 graphene-doped PVA） considerably passivates or reduces the magnitude of the surface states. The large change or dispersion in main electrical parameters can be attributed to generation of electron-hole pairs in the junction under illumination and to a good light absorption. All of these experimental results confirm that the fabricated Au/0.03 graphene-doped PVA/n-Si structure can be used as a photodiode or a capacitor in optoelectronic applications.
