AIM:To assess the corneal high-order aberration(HOA)and its correlation with corneal morphological parameters in patients with bilateral keratoconus(KCN)and unilateral Vogt’s striae.METHODS:A total of 168 eyes of 84 ...AIM:To assess the corneal high-order aberration(HOA)and its correlation with corneal morphological parameters in patients with bilateral keratoconus(KCN)and unilateral Vogt’s striae.METHODS:A total of 168 eyes of 84 patients with KCN,whose corneas had definite signs of unilateral Vogt’s striae,were enrolled.Corneal HOA and morphological parameters were measured using Pentacam HR.RESULTS:The corneal morphological parameters between KCN eyes with and without Vogt’s striae were evidently different(P<0.001).The 3rd coma 90°,4th spherical aberration,5th coma 90°,root-mean-square(RMS)(total),and RMS(HOA)in the front,back surfaces and total cornea in KCN eyes with Vogt’s striae were significantly higher than those in KCN eyes without Vogt’s striae(P<0.001).In KCN eyes with Vogt’s striae,the 3rd coma 90°and 4th spherical aberration in the front surface and total cornea were negatively correlated with flat keratometry value(K1),steep keratometry value(K2),mean keratometry value(Km),maximum keratometry value(Kmax),anterior corneal elevation(ACE),and posterior corneal elevation(PCE;P<0.05).The 3rd coma 90°,4th spherical aberration in back surface and RMS(total),RMS(HOA)in the front,back surfaces,total cornea were positively correlated with K1,K2,Km,Kmax,ACE,and PCE(P<0.05).CONCLUSION:Corneal HOA especially vertical coma and spherical aberration may increase when Vogt’s striae appeared in KCN eyes.The scale of increase is significantly related with changes in corneal shapes.展开更多
The possibility of the application of autologic pluripotent cells from peripheral blood (APCPB) for correction of striae after pregnancy was studied. Visually first signs of improvement of atrophic scars can be notice...The possibility of the application of autologic pluripotent cells from peripheral blood (APCPB) for correction of striae after pregnancy was studied. Visually first signs of improvement of atrophic scars can be noticed in 6-8 weeks after injection of APCPB and gradually progress during 6 months. The atrophy of epithelium, hyperkeratosis, sclerosis of all dermis layers with smoothing of papillae, reduction of number of blood vessels and skin appendages were found before treatment by method of light mi-croscopy. In all observations after injection of APCPB in a connective tissue, which replaces of dermis, an increase of number of vessels at the expense of processes of neoangiogenesis, leukocytic infiltration reduction, thinning and ordering of arrangement of collagen and elastin fibers were detected. These results give a chance for more successful application of cosmetology procedures for correction of these defects of skin.展开更多
Background/Aims: The association between striae gravidarum (SG) and preterm delivery may be postulated because of sharing similar poor organization of extracellular matrix in both skin and cervix. Our goal was to comp...Background/Aims: The association between striae gravidarum (SG) and preterm delivery may be postulated because of sharing similar poor organization of extracellular matrix in both skin and cervix. Our goal was to compare the frequency of striae gravidarum in women who gave preterm birth and women who gave term birth. Methods: A case-control study was conducted in women who gave preterm birth (n = 66) and age matched women who gave term birth (n = 68). Cases and controls were recruited from puerperal women consequently seen at delivery wards of perinatology unit. All women underwent dermatologic examination in terms of SG blindly to theirs gestational weeks of delivery. The frequency of SG was compared in all groups. Results: The frequency of SG was 63.6% in women with preterm birth and 54.4% in women with term birth (p = 0.278). SG is five times more common in late preterm group than in women with term group, but this difference was not statistically significant [(p = 0.227, OR: 5.02, CI 95% (0.5 - 44.0)]. The rate of preventive cream usage was not statistically different in women with SG and without SG (p = 0.245). Conclusions: It seems that there was no statistically significant association between the risk of preterm labor and the presence of striae gravidarum. Larger prospective observational studies are needed to state expressly the probable clinical association between the presence of SG and preterm delivery.展开更多
The pathogenesis of striae distensae(SD) is complicated and has not yet been fully elucidated. Hormonal changes,overstretched skin, and structural and functional changes in the skin may be crucial factors in the devel...The pathogenesis of striae distensae(SD) is complicated and has not yet been fully elucidated. Hormonal changes,overstretched skin, and structural and functional changes in the skin may be crucial factors in the development of SD. Therapy aims to stimulate dermal collagen synthesis and improve skin texture. Mainstream treatments include topical medications, chemical peeling, laser and radiofrequency therapy, microdermabrasion, microneedle therapy, and filler injection therapy. In the present review, we summarize current perspectives on the pathogenesis and clinical therapy of SD.展开更多
By recruiting 30 participants with striae gravidarum and using anti-wrinkle skincare products as an intervention measure,skin elasticity testing,skin firmness testing,and stretch mark image collection were conducted b...By recruiting 30 participants with striae gravidarum and using anti-wrinkle skincare products as an intervention measure,skin elasticity testing,skin firmness testing,and stretch mark image collection were conducted before use the anti-wrinkle skincare products,on the 14th,28th,and 56th day of use the antiwrinkle skincare products,respectively.Combined with visual evaluation by researchers and self-assessment by participants,the role of anti-wrinkle skincare products in improving stretch marks during pregnancy was explored.The results showed that on the 14th,28th,and 56th day of using efficacy skincare products,the average depth,area,and volume of stretch marks in the test area decreased compared to the baseline values before use and showed statistical differences(P<0.05);The measured values of R5 and R7 parameters for evaluating skin elasticity at the test site were significantly higher than the baseline values before use(P<0.05).On the 28th and 56th day of using efficacy skincare products,the measured values of the skin firmness evaluation parameters in the test area decreased significantly compared to the baseline values before use,and there was a statistical difference(P<0.05).The scores of the number,depth,and skin laxity of abdominal stretch marks in the visual assessment of the researchers and self-assessment of the subjects were significantly reduced on days 14,28,and 56 compared to before using the anti-wrinkle skincare product(P<0.05).This suggests that the anti-wrinkle skincare product has the effect of improving the elasticity and firmness of the skin in subjects with striae gravidarum,as well as improving striae gravidarum.展开更多
目的:探究A型肉毒素(Botulinum toxin A for therapeutic use,BTXA)不同分区多点注射对下睑纹改善中的美学效果及安全性。方法:选取2021年6月至2022年7月期间本院门诊收治的存在下睑纹的患者180例作为研究对象,随机分成对照组和观察组,...目的:探究A型肉毒素(Botulinum toxin A for therapeutic use,BTXA)不同分区多点注射对下睑纹改善中的美学效果及安全性。方法:选取2021年6月至2022年7月期间本院门诊收治的存在下睑纹的患者180例作为研究对象,随机分成对照组和观察组,每组90例。对照组采用BTXA三点注射法,观察组采用BTXA不同分区多点注射法,治疗时长m。比较两组的瘙痒程度、下睑纹改善情况、美学效果(Global aesthetic improvement scale,GAIS)、不良反应和满意度。结果:观察组瘙痒评分高于对照组(P<0.05);与治疗前相比,两组的皱纹分级评分降低,GAIS评分增加(P<0.05),其中观察组更为显著(P<0.05);观察组不良反应发生率低于对照组(P<0.05);观察组的满意率高于对照组(P<0.05)。结论:采用BTXA不同分区多点注射相比于三点注射具有更高的疗效、美学效果和安全性,提高患者满意度。展开更多
基金Supported by Xi’an Health Committee Research Projects(No.2023yb14)Shaanxi Province Natural Science Basic Research Project(No.2024JC-YBMS-623)Shaanxi Province Science and Technology Plan Project(No.2024SFYBXM-331).
文摘AIM:To assess the corneal high-order aberration(HOA)and its correlation with corneal morphological parameters in patients with bilateral keratoconus(KCN)and unilateral Vogt’s striae.METHODS:A total of 168 eyes of 84 patients with KCN,whose corneas had definite signs of unilateral Vogt’s striae,were enrolled.Corneal HOA and morphological parameters were measured using Pentacam HR.RESULTS:The corneal morphological parameters between KCN eyes with and without Vogt’s striae were evidently different(P<0.001).The 3rd coma 90°,4th spherical aberration,5th coma 90°,root-mean-square(RMS)(total),and RMS(HOA)in the front,back surfaces and total cornea in KCN eyes with Vogt’s striae were significantly higher than those in KCN eyes without Vogt’s striae(P<0.001).In KCN eyes with Vogt’s striae,the 3rd coma 90°and 4th spherical aberration in the front surface and total cornea were negatively correlated with flat keratometry value(K1),steep keratometry value(K2),mean keratometry value(Km),maximum keratometry value(Kmax),anterior corneal elevation(ACE),and posterior corneal elevation(PCE;P<0.05).The 3rd coma 90°,4th spherical aberration in back surface and RMS(total),RMS(HOA)in the front,back surfaces,total cornea were positively correlated with K1,K2,Km,Kmax,ACE,and PCE(P<0.05).CONCLUSION:Corneal HOA especially vertical coma and spherical aberration may increase when Vogt’s striae appeared in KCN eyes.The scale of increase is significantly related with changes in corneal shapes.
文摘The possibility of the application of autologic pluripotent cells from peripheral blood (APCPB) for correction of striae after pregnancy was studied. Visually first signs of improvement of atrophic scars can be noticed in 6-8 weeks after injection of APCPB and gradually progress during 6 months. The atrophy of epithelium, hyperkeratosis, sclerosis of all dermis layers with smoothing of papillae, reduction of number of blood vessels and skin appendages were found before treatment by method of light mi-croscopy. In all observations after injection of APCPB in a connective tissue, which replaces of dermis, an increase of number of vessels at the expense of processes of neoangiogenesis, leukocytic infiltration reduction, thinning and ordering of arrangement of collagen and elastin fibers were detected. These results give a chance for more successful application of cosmetology procedures for correction of these defects of skin.
文摘Background/Aims: The association between striae gravidarum (SG) and preterm delivery may be postulated because of sharing similar poor organization of extracellular matrix in both skin and cervix. Our goal was to compare the frequency of striae gravidarum in women who gave preterm birth and women who gave term birth. Methods: A case-control study was conducted in women who gave preterm birth (n = 66) and age matched women who gave term birth (n = 68). Cases and controls were recruited from puerperal women consequently seen at delivery wards of perinatology unit. All women underwent dermatologic examination in terms of SG blindly to theirs gestational weeks of delivery. The frequency of SG was compared in all groups. Results: The frequency of SG was 63.6% in women with preterm birth and 54.4% in women with term birth (p = 0.278). SG is five times more common in late preterm group than in women with term group, but this difference was not statistically significant [(p = 0.227, OR: 5.02, CI 95% (0.5 - 44.0)]. The rate of preventive cream usage was not statistically different in women with SG and without SG (p = 0.245). Conclusions: It seems that there was no statistically significant association between the risk of preterm labor and the presence of striae gravidarum. Larger prospective observational studies are needed to state expressly the probable clinical association between the presence of SG and preterm delivery.
基金supported by the National Natural Science Foundation of China(grant no.81873937)。
文摘The pathogenesis of striae distensae(SD) is complicated and has not yet been fully elucidated. Hormonal changes,overstretched skin, and structural and functional changes in the skin may be crucial factors in the development of SD. Therapy aims to stimulate dermal collagen synthesis and improve skin texture. Mainstream treatments include topical medications, chemical peeling, laser and radiofrequency therapy, microdermabrasion, microneedle therapy, and filler injection therapy. In the present review, we summarize current perspectives on the pathogenesis and clinical therapy of SD.
文摘By recruiting 30 participants with striae gravidarum and using anti-wrinkle skincare products as an intervention measure,skin elasticity testing,skin firmness testing,and stretch mark image collection were conducted before use the anti-wrinkle skincare products,on the 14th,28th,and 56th day of use the antiwrinkle skincare products,respectively.Combined with visual evaluation by researchers and self-assessment by participants,the role of anti-wrinkle skincare products in improving stretch marks during pregnancy was explored.The results showed that on the 14th,28th,and 56th day of using efficacy skincare products,the average depth,area,and volume of stretch marks in the test area decreased compared to the baseline values before use and showed statistical differences(P<0.05);The measured values of R5 and R7 parameters for evaluating skin elasticity at the test site were significantly higher than the baseline values before use(P<0.05).On the 28th and 56th day of using efficacy skincare products,the measured values of the skin firmness evaluation parameters in the test area decreased significantly compared to the baseline values before use,and there was a statistical difference(P<0.05).The scores of the number,depth,and skin laxity of abdominal stretch marks in the visual assessment of the researchers and self-assessment of the subjects were significantly reduced on days 14,28,and 56 compared to before using the anti-wrinkle skincare product(P<0.05).This suggests that the anti-wrinkle skincare product has the effect of improving the elasticity and firmness of the skin in subjects with striae gravidarum,as well as improving striae gravidarum.
文摘目的:探究A型肉毒素(Botulinum toxin A for therapeutic use,BTXA)不同分区多点注射对下睑纹改善中的美学效果及安全性。方法:选取2021年6月至2022年7月期间本院门诊收治的存在下睑纹的患者180例作为研究对象,随机分成对照组和观察组,每组90例。对照组采用BTXA三点注射法,观察组采用BTXA不同分区多点注射法,治疗时长m。比较两组的瘙痒程度、下睑纹改善情况、美学效果(Global aesthetic improvement scale,GAIS)、不良反应和满意度。结果:观察组瘙痒评分高于对照组(P<0.05);与治疗前相比,两组的皱纹分级评分降低,GAIS评分增加(P<0.05),其中观察组更为显著(P<0.05);观察组不良反应发生率低于对照组(P<0.05);观察组的满意率高于对照组(P<0.05)。结论:采用BTXA不同分区多点注射相比于三点注射具有更高的疗效、美学效果和安全性,提高患者满意度。
