To obtain the design parameters of the structure made by ecological high ductility cementitious composites(Eco-HDCC),the effects of curing age on the compressive and tensile stress-strain relationships were studied.Th...To obtain the design parameters of the structure made by ecological high ductility cementitious composites(Eco-HDCC),the effects of curing age on the compressive and tensile stress-strain relationships were studied.The reaction degree of fly ash,non-evaporable water content and the pH value in pore solution were calculated to reveal the mechanical property.The results indicate that as the curing age increases,the peak compressive strength,peak compressive strain and ultimate tensile strength of Eco-HDCC increase.However,the ultimate compressive strain and ultimate tensile strain of Eco-HDCC decrease with the increase in curing age.Besides,as the curing age increases,the reaction degree of fly ash and non-evaporable water content in Eco-HDCC increase,while the pH value in the pore solution of Eco-HDCC decreases.Finally,the simplified compressive and tensile stress-strain constitutive relationship models of Eco-HDCC with a curing age of 28 d were suggested for the structure design safety.展开更多
The stress-strain behavior of confined concrete under heating and residual conditions has been preliminarily addressed in previous research;however,its behavior at subsequent cooling temperatures after being heated to...The stress-strain behavior of confined concrete under heating and residual conditions has been preliminarily addressed in previous research;however,its behavior at subsequent cooling temperatures after being heated to peak temperature has yet to be thoroughly investigated.It is crucial for determining confined concrete structures’post-fire performance and burnout resistance.The paper presents the fundamental behavior of the confined concrete constitutive parameters and stress-strain curve at subsequent cooling temperatures after being heated to peak temperature.The study includes the stress-stress relationship of a 200 mm diameter cylinder with two distinct confinement spacings of 60 mm and 120 mm.The constitutive parameters for confined concrete were initially determined for a peak heating temperature of 750℃ and then modified to establish the stress-strain relationship for successive cooling temperatures of 500℃,250℃,and ambient temperature.The study results show that confinement has a considerable impact on compressive strength,stiffness,and ductility at ambient and fire conditions.After being heated to peak temperature,the confined concrete compressive strength recovers during successive cooling temperatures,with the recovery dependent on confinement spacing.The established stress-strain relationship can assist in better comprehending structural performance and capacity degradation for different tie spacings,and is useful for the analysis and design of confined RC(reinforced concrete)elements during and after a fire.展开更多
The mechanical behavior of plastic concrete used in the cut-off walls of earth dams has been studied. Triaxial compression tests on the specimens in various ages and mix designs under different confining pressures hav...The mechanical behavior of plastic concrete used in the cut-off walls of earth dams has been studied. Triaxial compression tests on the specimens in various ages and mix designs under different confining pressures have been done and the stress-strain behavior of such materials and their strength parameter changes have been experimentally investigated. It has been observed that increasing the confining pressures applied on the specimens causes the material behavior to be alike the more ductile materials and the compressive strength increases considerably as well. Moreover, a parametric study has been carded out to investigate the influence of essential parameters on the shear strength parameters of these materials. According to the research, increasing the coarse to fine aggregates ratio leads to the increase of compressive strength of the specimens as well as the increase of the cohesion and internal friction angle of the materials. Furthermore, the bentonite content decrease and the cement factor increase result in an increase of the cohesion parameter of plastic concretes and decrease of the internal friction angle of such materials.展开更多
Tracheal stents are an important form of treatment for benign or malignant central airway obstruction.However,the mechanical behavior of current tracheal stents is significantly different from that of the native trach...Tracheal stents are an important form of treatment for benign or malignant central airway obstruction.However,the mechanical behavior of current tracheal stents is significantly different from that of the native trachea,which leads to a variety of serious complications.In this study,inspired by the structure of the native trachea,a wavy non-uniform ligament chiral tracheal stent is proposed,in which J-shaped stress-strain behavior and negative Poisson's ratio response are achieved by replacing the tangential ligament of tetrachiral and anti-tetrachiral hybrid structure with a wavy non-uniform ligament.Through the combination of theoretical analysis,finite element analysis and experimental tests,a wide range of desired J-shaped stress-strain curves are explored to mimic the native porcine trachea by tailoring the stent geometry.Besides,the negative Poisson’s ratio and auxetic diameter curves versus axial strain of the stent are also studied in detail,thus contributing to the enhancement of cross-section ventilation and reducing the migration of the stent.This novel tracheal stent with a unique microstructure shows a potential to perfectly match the physiological activities of the native trachea and thereby reduce potential complications.展开更多
Tensile stress-strain curves of five metallic alloys,i.e.,SKH51,STS316L,Ti-6Al-4V,Al6061and Inconel600were analyzed to investigate the working hardening behavior.The constitutive parameters of three constitutive equat...Tensile stress-strain curves of five metallic alloys,i.e.,SKH51,STS316L,Ti-6Al-4V,Al6061and Inconel600were analyzed to investigate the working hardening behavior.The constitutive parameters of three constitutive equations,i.e.,the Hollomon,Swift and Voce equations,were compared by using different methods.A new working hardening parameter was proposed to characterize the working hardening behavior in different deformation stages.It is found that Voce equation is suitable to describe stress-strain curves in large strain region.Meanwhile,the predicting accuracy of ultimate tensile strength by Voce equation is the best.The working hardening behavior of SKH51is different from the other four metallic alloys.展开更多
In this paper the relationship between microstructure and stress-strain behavior in tensile test of high strength pipeline steel was investigated.The steel with polygonal ferrite-bainite(PF+B)microstructure has a"...In this paper the relationship between microstructure and stress-strain behavior in tensile test of high strength pipeline steel was investigated.The steel with polygonal ferrite-bainite(PF+B)microstructure has a"round-house"type tensile stress-strain curve with low Y/T ratio,highly uniform elongation and high n-value,which means PF+B microstructure has the best deformability(i.e.Ideal stress-strain behavior)among the four microstructures.The steel with acicular ferrite-martensite&austenite(AF+MA)microstructure has a"continuous-yielding"type tensile stress-strain curve,whose deformability is worse than that of PF+B microstructure.Both the steels of polygonal ferrite-acicular ferrite(PF+AF)and polygonal ferrite-pearlite(PF+P)microstructure have"luders elongation"type tensile stress-strain curve with high Y/T ratio,low uniform elongation and low n-value,which means PF+AF and PF+P microstructures have the worst deformability among the four microstructures.展开更多
To completely understand the rate-dependent stress-strain behavior of the porous nanocrystalline materials,it is necessary to formulate a constitutive model that can reflect the complicated experimentally observed str...To completely understand the rate-dependent stress-strain behavior of the porous nanocrystalline materials,it is necessary to formulate a constitutive model that can reflect the complicated experimentally observed stress-strain relations of nanocrystalline materials.The nanocrystalline materials consisting grain interior and grain boundary are considered as viscoplastic and porous materials for the reasons that their mechanical deformation is commonly governed by both dislocation glide and diffusion,and pores commonly exist in the nanocrystalline materials.A constitutive law of the unified theory reflecting the stress-strain relations was established and verified by experimental data of bulk nanocrystalline Ni prepared by hydrogen direct current arc plasma evaporation method and hot compression.The effect of the evolution of porosity on stress-strain relations was taken into account to make that the predicted results can keep good agreements with the corresponding experimental results.展开更多
As a critical mechanical characteristic of rock,brittleness significantly influences fracture modes and damage evolution processes.Accurate quantitative evaluation of brittleness is essential for ensuring the stabilit...As a critical mechanical characteristic of rock,brittleness significantly influences fracture modes and damage evolution processes.Accurate quantitative evaluation of brittleness is essential for ensuring the stability of various engineering applications.Based on the pre-peak and post-peak stages of the rock stress-strain curve,this study constructed a brittleness index BI^(*).The index quantifies the ability of rock to resist plastic deformation during the pre-peak crack growth stage and evaluates the intensity of strength drop during the post-peak softening stage.Another index,BII,was established based on the degree of pre-peak elastic energy accumulation and the instability characteristics of post-peak dissipated energy.This index reflects the essential properties of rock failure by revealing the energy evolution mechanism.Furthermore,by defining a damage variable from the energy dissipation over the entire deformation process,an index B_(D)was introduced to evaluate brittleness from the perspective of internal damage development.Triaxial compression and cyclic loading tests were conducted on rocks of different lithologies to evaluate the new index.The influences of confining pressure and lithology on rock brittleness were analyzed,along with the sensitivity analysis of various brittleness index parameters.The results indicated that the proposed brittleness indices accurately distinguish the brittleness differences among various lithologies and show effective consistency with the failure modes of specimens under different confining pressures.Meanwhile,different brittleness indices were affected by confining pressure and lithology to different degrees.The post-peak softening stage of rock played a particularly significant role in brittleness analysis.A brittleness classification system under different confining pressures and lithologies was established.The research results contribute to the enhancement and refinement of the rock brittleness evaluation system.展开更多
Correction to:Nano-Micro Letters(2026)18:10.https://doi.org/10.1007/s40820-025-01852-8 Following publication of the original article[1],the authors reported that the last author’s name was inadvertently misspelled.Th...Correction to:Nano-Micro Letters(2026)18:10.https://doi.org/10.1007/s40820-025-01852-8 Following publication of the original article[1],the authors reported that the last author’s name was inadvertently misspelled.The published version showed“Hongzhen Chen”,whereas the correct spelling should be“Hongzheng Chen”.The correct author name has been provided in this Correction,and the original article[1]has been corrected.展开更多
This study utilizes wet/dry cyclic corrosion testing combined with corrosion big data technology to investigate the mechanism by which chloride ions(Cl^(-))influence the corrosion behavior of 650 MPa high-strength low...This study utilizes wet/dry cyclic corrosion testing combined with corrosion big data technology to investigate the mechanism by which chloride ions(Cl^(-))influence the corrosion behavior of 650 MPa high-strength low-alloy(HSLA)steel in industrially polluted environments.The corrosion process of 650 MPa HSLA steel occurred in two distinct stages:an initial corrosion stage and a stable corrosion stage.During the initial phase,the weight loss rate increased rapidly owing to the instability of the rust layer.Notably,this study demonstrated that 650 MPa HSLA steel exhibited superior corrosion resistance in Cl-containing environments.The formation of a corrosion-product film eventually reduced the weight-loss rate.However,the intrusion of Cl^(-)at increasing concentrations gradually destabilized theα/γ^(*)phases of the rust layer,leading to a looser structure and lower polarization resistance(R_(p)).The application of corrosion big data technology in this study facilitated the validation and analysis of the experimental results,offering new insights into the corrosion mechanisms of HSLA steel in chloride-rich environments.展开更多
BACKGROUND Despite societal guidelines recommending targeted screening for Barrett’s esophagus(BE)and esophageal adenocarcinoma(EAC)in individuals with gastroesophageal reflux symptoms(GERS),screening adherence is su...BACKGROUND Despite societal guidelines recommending targeted screening for Barrett’s esophagus(BE)and esophageal adenocarcinoma(EAC)in individuals with gastroesophageal reflux symptoms(GERS),screening adherence is suboptimal.Current screening approaches fail to identify individuals not seeking medical consultation for GERS or whose GERS are managed with‘over-the-counter’(OTC)acid suppressant therapies.AIM To assess patients’self-management and help-seeking behavior for GERS.METHODS This cross-sectional study collected data from the Dutch general population aged 18-75 years between January and April 2023 using a web-based survey.The survey included questions regarding self-management(e.g.,use of acid suppressant therapy with or without prescription)and help-seeking behavior(e.g.,consulting a primary care provider)for GERS.Simple random sampling was performed to select individuals within the target age group.In total,18156 randomly selected individuals were invited to participate.The study protocol was registered in ClinicalTrials.gov(identifier:NCT05689918).RESULTS Of the 18156 invited individuals,3214 participants(17.7%)completed the survey,of which 1572 participants(48.9%)reported GERS.Of these,904 participants(57.5%)had never consulted a primary care provider for these symptoms,of which 331 participants(36.6%)reported taking OTC acid suppressant therapy in the past six months and 100 participants(11.1%)fulfilled the screening criteria for BE and EAC according to the European Society of Gastrointestinal Endoscopy Guideline.CONCLUSION The population fulfilling the screening criteria for BE and EAC is incompletely identified,suggesting potential underutilization of medical consultation.Raising public awareness of GERS as a risk factor for EAC is needed.展开更多
BACKGROUND Due to the dry and cold climate,the obvious temperature difference between day and night,and the low oxygen content of the air in the plateau area,people are prone to upper respiratory tract diseases,and of...BACKGROUND Due to the dry and cold climate,the obvious temperature difference between day and night,and the low oxygen content of the air in the plateau area,people are prone to upper respiratory tract diseases,and often the condition is prolonged,and the patients are prone to anxiety and uneasiness,which may be related to the harshness of the plateau environment,somatic discomfort due to the lack of oxygen,anxiety about the disease,and other factors.AIM To investigate the effects of cognitive behavioral therapy(CBT)on anxiety,sleep disorders,and hypoxia tolerance in patients with high-altitude respiratory diseases.METHODS A total of 2337 patients with high-altitude-related respiratory diseases treated at our hospital between November 2023 and January 2024 were selected as the study subjects.The subjects’pre-high-altitude residential altitude was approximately 1700 meters.They were divided into two groups.Both groups were given symptomatic treatment,and the control group implemented conventional nursing intervention,while the research group simultaneously conducted CBT intervention;assessed the degree of health knowledge of the two groups,and applied the Hamilton Anxiety Scale and the Pittsburgh Sleep Quality Index to assess the anxiety and sleep quality of the patients before and after the intervention,respectively.It also observed the length and efficiency of sleep,and detected the level of serum hypoxia inducible factor-1α,erythropoietin(EPO)and clinical intervention before and after intervention.EPO levels,and investigated satisfaction with the clinical intervention.RESULTS The rate of excellent health knowledge in the intervention group was 93.64%,which was higher than that in the control group(74.23%;P<0.05).Before the intervention,there was no significant difference in Hamilton Anxiety Scale and Pittsburgh Sleep Quality Index scores between the two groups(P>0.05),and after the intervention,the scores of the study group were significantly lower than those of the control group(P<0.05).There was no significant difference in sleep duration and sleep efficiency between the groups before the intervention(P>0.05),and after the intervention,the scores of the study group were significantly larger than those of the control group(P<0.05).There was no significant difference in serum hypoxia inducible factor-1αand EPO between the two groups before intervention(P>0.05),and both research groups were significantly lower than the control group after intervention(P<0.05).According to the questionnaire survey,the intervention satisfaction of the study group was 95.53%,which was higher than that of the control group(80.14%;P<0.05).CONCLUSION The CBT intervention in the treatment of patients with high-altitude-related respiratory diseases helps improve patients'health knowledge,relieve anxiety,improve sleep quality and hypoxia tolerance,and improve nursing satisfaction.展开更多
BACKGROUND Approximately 30%of patients with head and neck cancer experience adverse effects caused by anxiety and depression.Considering the high prevalence,implementing customized interventions to ease adverse emoti...BACKGROUND Approximately 30%of patients with head and neck cancer experience adverse effects caused by anxiety and depression.Considering the high prevalence,implementing customized interventions to ease adverse emotional states is imperative.AIM To evaluate the efficacy of cognitive behavioral therapy(CBT)-based psychological interventions in improving the psychological well-being and quality of life(QoL)of patients with laryngeal carcinoma.METHODS This study enrolled 120 patients admitted from February 2022 to February 2024.The control group,comprising 50 participants,received standard supportive psychological care,while the research group,consisting 70 participants,underwent CBT-based interventions.Several clinical outcomes were systematically assessed that included postoperative recovery metrics(duration of tracheostomy and nasogastric tube dependence and length of hospitalization),psychological status(Self-Rating Anxiety Scale and Self-Rating Depression Scale),nutritional markers(serum albumin and hemoglobin levels),sleep quality(Self-Rating Scale of Sleep and Athens Insomnia Scale),and QoL(Functional Assessment of Cancer Therapy-Head and Neck).RESULTS The results demonstrated that the research group experienced superior outcomes,with significantly reduced durations of tracheostomy and nasogastric tube dependence,as well as shorter hospital stays,compared with the control group.Additionally,the research group exhibited markedly lower post-intervention Self-Rating Anxiety Scale,Self-Rating Depression Scale,Self-Rating Scale of Sleep,and Athens Insomnia Scale scores,along with minimal but higher change in serum albumin and hemoglobin levels compared with the control group.All five domains of Functional Assessment of Cancer Therapy-Head and Neck showed notable improvements in the research group,exceeding those observed in the control group.CONCLUSION CBT-based psychological support positively affects the mental well-being and QoL of patients with laryngeal carcinoma,highlighting its potential for broader clinical application.展开更多
Healthy behavior has long been linked to mental health outcomes.However,the role of artificial intelligence(AI)literacy in shaping healthy behaviors and its potential impact on mental health remains underexplored.This...Healthy behavior has long been linked to mental health outcomes.However,the role of artificial intelligence(AI)literacy in shaping healthy behaviors and its potential impact on mental health remains underexplored.This paper presents a scoping review offering a novel perspective on the intersection of healthy behaviors,mental health,and AI literacy.By examining how individuals’understanding of AI influences their choices regarding nutrition and their susceptibility to mental health issues,the current study explores emerging trends in health behavior decision-making.This emphasizes the need for integrating AI literacy into mental health and health behaviors education,as well as the development of AI-driven tools to support healthier behavior choices.It highlights that individuals with low AI literacy may misinterpret or overly depend on AI guidance,resulting in maladaptive health choices,while those with high AI literacy may be more likely to engage reflectively and sustain positive behaviors.The paper outlines the importance of inclusive education,user-centered design,and community-based support systems to enhance AI literacy for digitally marginalized groups.AI literacy may be positioned as a key determinant of health equity,better allowing for interdisciplinary strategies that empower individuals to make informed,autonomous decisions that promote both physical and mental health.展开更多
Mesenchymal stem cell-derived extracellular vesicles have emerged as a promising form of regenerative and immunomodulatory therapy;indeed,micro(mi)RNAs contained within mesenchymal stem cell-derived extracellular vesi...Mesenchymal stem cell-derived extracellular vesicles have emerged as a promising form of regenerative and immunomodulatory therapy;indeed,micro(mi)RNAs contained within mesenchymal stem cell-derived extracellular vesicles modulate target gene expression and impact disease-associated pathways.Chronic alcohol consumption leads to neuroinflammation,brain damage,and impaired cognition.Evidence indicates that females are more vulnerable to alcohol-induced damage than males.While mesenchymal stem cell-derived extracellular vesicles have been studied in various neuroinflammatory conditions,their potential to counteract alcohol-induced brain damage remains unclear.In this study,we investigated whether repeated intravenous administration of mesenchymal stem cell-derived extracellular vesicles could ameliorate neuroinflammation and behavioral impairment induced by chronic alcohol consumption in female mice.Mesenchymal stem cell-derived extracellular vesicles diminished the increased binding of a micro-positron emission tomography tracer(^(18)F-FDG)when analyzing whole-brain 3D images and brain coronal sections of ethanol-treated mice.Mesenchymal stem cell-derived extracellular vesicle administration protected against ethanol-induced proinflammatory gene upregulation,cognitive dysfunction,and the conditioned rewarding effects of cocaine.MiRNA sequencing data from mesenchymal stem cell-derived extracellular vesicles revealed the elevated expression of extracellular vesicle-derived miR-483-5p and miR-140-3p in the brains of ethanol-treated female mice following mesenchymal stem cell-derived extracellular vesicle administration.In addition,mesenchymal stem cell-derived extracellular vesicles modulated the expression of pro-inflammatory-related miRNA target genes(e.g.,Socs3,Tnf,Mtor,and Atf6)in the brains of ethanol-treated female mice.These results suggest that mesenchymal stem cell-derived extracellular vesicles could function as a neuroprotective therapy to ameliorate the neuroinflammation,cognitive dysfunction,and conditioned rewarding effects of cocaine associated with chronic alcohol consumption.展开更多
This paper prepared a novel as-cast W-Zr-Ti metallic ESM using high-frequency vacuum induction melting technique.The above ESM performs a typical elastic-brittle material feature and strain rate strengthening behavior...This paper prepared a novel as-cast W-Zr-Ti metallic ESM using high-frequency vacuum induction melting technique.The above ESM performs a typical elastic-brittle material feature and strain rate strengthening behavior.The specimens exhibit violent chemical reaction during the fracture process under the impact loading,and the size distribution of their residual debris follows Rosin-Rammler model.The dynamic fracture toughness is obtained by the fitting of debris length scale,approximately 1.87 MPa·m~(1/2).Microstructure observation on residual debris indicates that the failure process is determined by primary crack propagation under quasi-static compression,while it is affected by multiple cracks propagation in both particle and matrix in the case of dynamic impact.Impact test demonstrates that the novel energetic fragment performs brilliant penetration and combustion effect behind the front target,leading to the effective ignition of fuel tank.For the brittleness of as-cast W-ZrTi ESM,further study conducted bond-based peridynamic(BB-PD)C++computational code to simulate its fracture behavior during penetration.The BB-PD method successfully captured the fracture process and debris cloud formation of the energetic fragment.This paper explores a novel as-cast metallic ESM,and provides an available numerical avenue to the simulation of brittle energetic fragment.展开更多
The dissimilar 2B06 and 7B04 Al alloy joints were prepared by refill friction stir spot welding(RFSSW),and the microstructural evolution and corrosion behavior of the joints were investigated.Based on microstructural ...The dissimilar 2B06 and 7B04 Al alloy joints were prepared by refill friction stir spot welding(RFSSW),and the microstructural evolution and corrosion behavior of the joints were investigated.Based on microstructural analysis,the welded joints exhibit distinct microstructural zones,including the stir zone(SZ),thermomechanically affected zone(TMAZ),and heat-affected zone(HAZ).The grain size of each zone is in the order of HAZ>TMAZ>SZ.Notably,the TMAZ and HAZ contain significantly larger secondary-phase particles compared to the SZ,with particle size in the HAZ increasing at higher rotational speeds.Electrochemical tests indicate that corrosion susceptibility follows the sequence of HAZ>TMAZ>SZ>BM,with greater sensitivity observed at increased rotational speeds.Post-corrosion mechanical performance degradation primarily arises from crevice corrosion at joint overlaps,but not from the changes in the microstructure.展开更多
In the competitive retail industry of the digital era,data-driven insights into gender-specific customer behavior are essential.They support the optimization of store performance,layout design,product placement,and ta...In the competitive retail industry of the digital era,data-driven insights into gender-specific customer behavior are essential.They support the optimization of store performance,layout design,product placement,and targeted marketing.However,existing computer vision solutions often rely on facial recognition to gather such insights,raising significant privacy and ethical concerns.To address these issues,this paper presents a privacypreserving customer analytics system through two key strategies.First,we deploy a deep learning framework using YOLOv9s,trained on the RCA-TVGender dataset.Cameras are positioned perpendicular to observation areas to reduce facial visibility while maintaining accurate gender classification.Second,we apply AES-128 encryption to customer position data,ensuring secure access and regulatory compliance.Our system achieved overall performance,with 81.5%mAP@50,77.7%precision,and 75.7%recall.Moreover,a 90-min observational study confirmed the system’s ability to generate privacy-protected heatmaps revealing distinct behavioral patterns between male and female customers.For instance,women spent more time in certain areas and showed interest in different products.These results confirm the system’s effectiveness in enabling personalized layout and marketing strategies without compromising privacy.展开更多
The functional properties of glasses are governed by their formation history and the complex relaxation processes they undergo.However,under extreme conditions,glass behaviors are still elusive.In this study,we employ...The functional properties of glasses are governed by their formation history and the complex relaxation processes they undergo.However,under extreme conditions,glass behaviors are still elusive.In this study,we employ simulations with varied protocols to evaluate the effectiveness of different descriptors in predicting mechanical properties across both low-and high-pressure regimes.Our findings demonstrate that conventional structural and configurational descriptors fail to correlate with the mechanical response following pressure release,whereas the activation energy descriptor exhibits robust linearity with shear modulus after correcting for pressure effects.Notably,the soft mode parameter emerges as an ideal and computationally efficient alternative for capturing this mechanical behavior.These findings provide critical insights into the influence of pressure on glassy properties,integrating the distinct features of compressed glasses into a unified theoretical framework.展开更多
The reservoir landslide undergoes periodic saturation-drying cycles affected by reservoir fluctuation in hydropower project area,leading to the irreversible impact on the landslide materials.Sliding zone is the sheari...The reservoir landslide undergoes periodic saturation-drying cycles affected by reservoir fluctuation in hydropower project area,leading to the irreversible impact on the landslide materials.Sliding zone is the shearing part in formation of landslide and controls the further development of landslide.The mechanical behavior of sliding zone soil under compression is a crucial factor in the stability analysis in landslides.In this paper,the sliding zone soil from a giant landslide in the biggest hydropower project area,Three Gorges Reservoir Area,is taken as the research case.The particlesize distribution of the sliding zone soil from this landslide is studied and fractal dimension is adopted as representation.Periodic saturation-drying is introduced as the affecting factor on sliding zone soil properties.The triaxial compression test is conducted to reveal the mechanical behavior of the soil,including stress-strain behavior,elastic modulus,failure stress and strength parameters.These behavior of sliding zone soils with different fractal dimensions are studied under the effects of periodic saturation-drying cycles.The normalized stress-strain curves are displayed for further calculation.The data considering saturation-drying cycles are obtained and compared with the experimental results.展开更多
基金The National Natural Science Foundations of China(No.51778133)the Transportation Science&Technology Project of Fujian Province(No.2017Y057)+1 种基金the China Railway Project(No.2017G007-C)Foundation of the China Scholarship Council(No.201906090163).
文摘To obtain the design parameters of the structure made by ecological high ductility cementitious composites(Eco-HDCC),the effects of curing age on the compressive and tensile stress-strain relationships were studied.The reaction degree of fly ash,non-evaporable water content and the pH value in pore solution were calculated to reveal the mechanical property.The results indicate that as the curing age increases,the peak compressive strength,peak compressive strain and ultimate tensile strength of Eco-HDCC increase.However,the ultimate compressive strain and ultimate tensile strain of Eco-HDCC decrease with the increase in curing age.Besides,as the curing age increases,the reaction degree of fly ash and non-evaporable water content in Eco-HDCC increase,while the pH value in the pore solution of Eco-HDCC decreases.Finally,the simplified compressive and tensile stress-strain constitutive relationship models of Eco-HDCC with a curing age of 28 d were suggested for the structure design safety.
文摘The stress-strain behavior of confined concrete under heating and residual conditions has been preliminarily addressed in previous research;however,its behavior at subsequent cooling temperatures after being heated to peak temperature has yet to be thoroughly investigated.It is crucial for determining confined concrete structures’post-fire performance and burnout resistance.The paper presents the fundamental behavior of the confined concrete constitutive parameters and stress-strain curve at subsequent cooling temperatures after being heated to peak temperature.The study includes the stress-stress relationship of a 200 mm diameter cylinder with two distinct confinement spacings of 60 mm and 120 mm.The constitutive parameters for confined concrete were initially determined for a peak heating temperature of 750℃ and then modified to establish the stress-strain relationship for successive cooling temperatures of 500℃,250℃,and ambient temperature.The study results show that confinement has a considerable impact on compressive strength,stiffness,and ductility at ambient and fire conditions.After being heated to peak temperature,the confined concrete compressive strength recovers during successive cooling temperatures,with the recovery dependent on confinement spacing.The established stress-strain relationship can assist in better comprehending structural performance and capacity degradation for different tie spacings,and is useful for the analysis and design of confined RC(reinforced concrete)elements during and after a fire.
文摘The mechanical behavior of plastic concrete used in the cut-off walls of earth dams has been studied. Triaxial compression tests on the specimens in various ages and mix designs under different confining pressures have been done and the stress-strain behavior of such materials and their strength parameter changes have been experimentally investigated. It has been observed that increasing the confining pressures applied on the specimens causes the material behavior to be alike the more ductile materials and the compressive strength increases considerably as well. Moreover, a parametric study has been carded out to investigate the influence of essential parameters on the shear strength parameters of these materials. According to the research, increasing the coarse to fine aggregates ratio leads to the increase of compressive strength of the specimens as well as the increase of the cohesion and internal friction angle of the materials. Furthermore, the bentonite content decrease and the cement factor increase result in an increase of the cohesion parameter of plastic concretes and decrease of the internal friction angle of such materials.
基金supported by the National Key Research and Development Program of China(No.2020YFC1107103)the National Natural Science Foundation of China(No.51821093)the Research Project of Public Welfare Technology Application of Zhejiang Province,China(No.LGF21H010006).
文摘Tracheal stents are an important form of treatment for benign or malignant central airway obstruction.However,the mechanical behavior of current tracheal stents is significantly different from that of the native trachea,which leads to a variety of serious complications.In this study,inspired by the structure of the native trachea,a wavy non-uniform ligament chiral tracheal stent is proposed,in which J-shaped stress-strain behavior and negative Poisson's ratio response are achieved by replacing the tangential ligament of tetrachiral and anti-tetrachiral hybrid structure with a wavy non-uniform ligament.Through the combination of theoretical analysis,finite element analysis and experimental tests,a wide range of desired J-shaped stress-strain curves are explored to mimic the native porcine trachea by tailoring the stent geometry.Besides,the negative Poisson’s ratio and auxetic diameter curves versus axial strain of the stent are also studied in detail,thus contributing to the enhancement of cross-section ventilation and reducing the migration of the stent.This novel tracheal stent with a unique microstructure shows a potential to perfectly match the physiological activities of the native trachea and thereby reduce potential complications.
基金Project(51275414)supported by the National Natural Science Foundation of ChinaProject(3102015BJ(Ⅱ)ZS007)supported by the Fundamental Research Funds for the Central Universities,ChinaProject(130-QP-2015)supported by the Research Fund of the State Key Laboratory of Solidification Processing(NWPU),China
文摘Tensile stress-strain curves of five metallic alloys,i.e.,SKH51,STS316L,Ti-6Al-4V,Al6061and Inconel600were analyzed to investigate the working hardening behavior.The constitutive parameters of three constitutive equations,i.e.,the Hollomon,Swift and Voce equations,were compared by using different methods.A new working hardening parameter was proposed to characterize the working hardening behavior in different deformation stages.It is found that Voce equation is suitable to describe stress-strain curves in large strain region.Meanwhile,the predicting accuracy of ultimate tensile strength by Voce equation is the best.The working hardening behavior of SKH51is different from the other four metallic alloys.
文摘In this paper the relationship between microstructure and stress-strain behavior in tensile test of high strength pipeline steel was investigated.The steel with polygonal ferrite-bainite(PF+B)microstructure has a"round-house"type tensile stress-strain curve with low Y/T ratio,highly uniform elongation and high n-value,which means PF+B microstructure has the best deformability(i.e.Ideal stress-strain behavior)among the four microstructures.The steel with acicular ferrite-martensite&austenite(AF+MA)microstructure has a"continuous-yielding"type tensile stress-strain curve,whose deformability is worse than that of PF+B microstructure.Both the steels of polygonal ferrite-acicular ferrite(PF+AF)and polygonal ferrite-pearlite(PF+P)microstructure have"luders elongation"type tensile stress-strain curve with high Y/T ratio,low uniform elongation and low n-value,which means PF+AF and PF+P microstructures have the worst deformability among the four microstructures.
基金Project(10502025) supported by the National Natural Science Foundation of ChinaProject(101005) supported by the Fok Ying Tong Education FoundationProject(BK2007528) supported by the Natural Science Foundation of Jiangsu Province,China
文摘To completely understand the rate-dependent stress-strain behavior of the porous nanocrystalline materials,it is necessary to formulate a constitutive model that can reflect the complicated experimentally observed stress-strain relations of nanocrystalline materials.The nanocrystalline materials consisting grain interior and grain boundary are considered as viscoplastic and porous materials for the reasons that their mechanical deformation is commonly governed by both dislocation glide and diffusion,and pores commonly exist in the nanocrystalline materials.A constitutive law of the unified theory reflecting the stress-strain relations was established and verified by experimental data of bulk nanocrystalline Ni prepared by hydrogen direct current arc plasma evaporation method and hot compression.The effect of the evolution of porosity on stress-strain relations was taken into account to make that the predicted results can keep good agreements with the corresponding experimental results.
基金support from the National Natural Science Foundation of China(Grant Nos.12072102 and 12102129).
文摘As a critical mechanical characteristic of rock,brittleness significantly influences fracture modes and damage evolution processes.Accurate quantitative evaluation of brittleness is essential for ensuring the stability of various engineering applications.Based on the pre-peak and post-peak stages of the rock stress-strain curve,this study constructed a brittleness index BI^(*).The index quantifies the ability of rock to resist plastic deformation during the pre-peak crack growth stage and evaluates the intensity of strength drop during the post-peak softening stage.Another index,BII,was established based on the degree of pre-peak elastic energy accumulation and the instability characteristics of post-peak dissipated energy.This index reflects the essential properties of rock failure by revealing the energy evolution mechanism.Furthermore,by defining a damage variable from the energy dissipation over the entire deformation process,an index B_(D)was introduced to evaluate brittleness from the perspective of internal damage development.Triaxial compression and cyclic loading tests were conducted on rocks of different lithologies to evaluate the new index.The influences of confining pressure and lithology on rock brittleness were analyzed,along with the sensitivity analysis of various brittleness index parameters.The results indicated that the proposed brittleness indices accurately distinguish the brittleness differences among various lithologies and show effective consistency with the failure modes of specimens under different confining pressures.Meanwhile,different brittleness indices were affected by confining pressure and lithology to different degrees.The post-peak softening stage of rock played a particularly significant role in brittleness analysis.A brittleness classification system under different confining pressures and lithologies was established.The research results contribute to the enhancement and refinement of the rock brittleness evaluation system.
文摘Correction to:Nano-Micro Letters(2026)18:10.https://doi.org/10.1007/s40820-025-01852-8 Following publication of the original article[1],the authors reported that the last author’s name was inadvertently misspelled.The published version showed“Hongzhen Chen”,whereas the correct spelling should be“Hongzheng Chen”.The correct author name has been provided in this Correction,and the original article[1]has been corrected.
基金financially supported by the National Natural Science Foundation of China(Nos.52104319 and 52374323)。
文摘This study utilizes wet/dry cyclic corrosion testing combined with corrosion big data technology to investigate the mechanism by which chloride ions(Cl^(-))influence the corrosion behavior of 650 MPa high-strength low-alloy(HSLA)steel in industrially polluted environments.The corrosion process of 650 MPa HSLA steel occurred in two distinct stages:an initial corrosion stage and a stable corrosion stage.During the initial phase,the weight loss rate increased rapidly owing to the instability of the rust layer.Notably,this study demonstrated that 650 MPa HSLA steel exhibited superior corrosion resistance in Cl-containing environments.The formation of a corrosion-product film eventually reduced the weight-loss rate.However,the intrusion of Cl^(-)at increasing concentrations gradually destabilized theα/γ^(*)phases of the rust layer,leading to a looser structure and lower polarization resistance(R_(p)).The application of corrosion big data technology in this study facilitated the validation and analysis of the experimental results,offering new insights into the corrosion mechanisms of HSLA steel in chloride-rich environments.
文摘BACKGROUND Despite societal guidelines recommending targeted screening for Barrett’s esophagus(BE)and esophageal adenocarcinoma(EAC)in individuals with gastroesophageal reflux symptoms(GERS),screening adherence is suboptimal.Current screening approaches fail to identify individuals not seeking medical consultation for GERS or whose GERS are managed with‘over-the-counter’(OTC)acid suppressant therapies.AIM To assess patients’self-management and help-seeking behavior for GERS.METHODS This cross-sectional study collected data from the Dutch general population aged 18-75 years between January and April 2023 using a web-based survey.The survey included questions regarding self-management(e.g.,use of acid suppressant therapy with or without prescription)and help-seeking behavior(e.g.,consulting a primary care provider)for GERS.Simple random sampling was performed to select individuals within the target age group.In total,18156 randomly selected individuals were invited to participate.The study protocol was registered in ClinicalTrials.gov(identifier:NCT05689918).RESULTS Of the 18156 invited individuals,3214 participants(17.7%)completed the survey,of which 1572 participants(48.9%)reported GERS.Of these,904 participants(57.5%)had never consulted a primary care provider for these symptoms,of which 331 participants(36.6%)reported taking OTC acid suppressant therapy in the past six months and 100 participants(11.1%)fulfilled the screening criteria for BE and EAC according to the European Society of Gastrointestinal Endoscopy Guideline.CONCLUSION The population fulfilling the screening criteria for BE and EAC is incompletely identified,suggesting potential underutilization of medical consultation.Raising public awareness of GERS as a risk factor for EAC is needed.
基金Supported by Army Logistics Department Health Bureau Project,No.QJGYXYJZX-012.
文摘BACKGROUND Due to the dry and cold climate,the obvious temperature difference between day and night,and the low oxygen content of the air in the plateau area,people are prone to upper respiratory tract diseases,and often the condition is prolonged,and the patients are prone to anxiety and uneasiness,which may be related to the harshness of the plateau environment,somatic discomfort due to the lack of oxygen,anxiety about the disease,and other factors.AIM To investigate the effects of cognitive behavioral therapy(CBT)on anxiety,sleep disorders,and hypoxia tolerance in patients with high-altitude respiratory diseases.METHODS A total of 2337 patients with high-altitude-related respiratory diseases treated at our hospital between November 2023 and January 2024 were selected as the study subjects.The subjects’pre-high-altitude residential altitude was approximately 1700 meters.They were divided into two groups.Both groups were given symptomatic treatment,and the control group implemented conventional nursing intervention,while the research group simultaneously conducted CBT intervention;assessed the degree of health knowledge of the two groups,and applied the Hamilton Anxiety Scale and the Pittsburgh Sleep Quality Index to assess the anxiety and sleep quality of the patients before and after the intervention,respectively.It also observed the length and efficiency of sleep,and detected the level of serum hypoxia inducible factor-1α,erythropoietin(EPO)and clinical intervention before and after intervention.EPO levels,and investigated satisfaction with the clinical intervention.RESULTS The rate of excellent health knowledge in the intervention group was 93.64%,which was higher than that in the control group(74.23%;P<0.05).Before the intervention,there was no significant difference in Hamilton Anxiety Scale and Pittsburgh Sleep Quality Index scores between the two groups(P>0.05),and after the intervention,the scores of the study group were significantly lower than those of the control group(P<0.05).There was no significant difference in sleep duration and sleep efficiency between the groups before the intervention(P>0.05),and after the intervention,the scores of the study group were significantly larger than those of the control group(P<0.05).There was no significant difference in serum hypoxia inducible factor-1αand EPO between the two groups before intervention(P>0.05),and both research groups were significantly lower than the control group after intervention(P<0.05).According to the questionnaire survey,the intervention satisfaction of the study group was 95.53%,which was higher than that of the control group(80.14%;P<0.05).CONCLUSION The CBT intervention in the treatment of patients with high-altitude-related respiratory diseases helps improve patients'health knowledge,relieve anxiety,improve sleep quality and hypoxia tolerance,and improve nursing satisfaction.
文摘BACKGROUND Approximately 30%of patients with head and neck cancer experience adverse effects caused by anxiety and depression.Considering the high prevalence,implementing customized interventions to ease adverse emotional states is imperative.AIM To evaluate the efficacy of cognitive behavioral therapy(CBT)-based psychological interventions in improving the psychological well-being and quality of life(QoL)of patients with laryngeal carcinoma.METHODS This study enrolled 120 patients admitted from February 2022 to February 2024.The control group,comprising 50 participants,received standard supportive psychological care,while the research group,consisting 70 participants,underwent CBT-based interventions.Several clinical outcomes were systematically assessed that included postoperative recovery metrics(duration of tracheostomy and nasogastric tube dependence and length of hospitalization),psychological status(Self-Rating Anxiety Scale and Self-Rating Depression Scale),nutritional markers(serum albumin and hemoglobin levels),sleep quality(Self-Rating Scale of Sleep and Athens Insomnia Scale),and QoL(Functional Assessment of Cancer Therapy-Head and Neck).RESULTS The results demonstrated that the research group experienced superior outcomes,with significantly reduced durations of tracheostomy and nasogastric tube dependence,as well as shorter hospital stays,compared with the control group.Additionally,the research group exhibited markedly lower post-intervention Self-Rating Anxiety Scale,Self-Rating Depression Scale,Self-Rating Scale of Sleep,and Athens Insomnia Scale scores,along with minimal but higher change in serum albumin and hemoglobin levels compared with the control group.All five domains of Functional Assessment of Cancer Therapy-Head and Neck showed notable improvements in the research group,exceeding those observed in the control group.CONCLUSION CBT-based psychological support positively affects the mental well-being and QoL of patients with laryngeal carcinoma,highlighting its potential for broader clinical application.
文摘Healthy behavior has long been linked to mental health outcomes.However,the role of artificial intelligence(AI)literacy in shaping healthy behaviors and its potential impact on mental health remains underexplored.This paper presents a scoping review offering a novel perspective on the intersection of healthy behaviors,mental health,and AI literacy.By examining how individuals’understanding of AI influences their choices regarding nutrition and their susceptibility to mental health issues,the current study explores emerging trends in health behavior decision-making.This emphasizes the need for integrating AI literacy into mental health and health behaviors education,as well as the development of AI-driven tools to support healthier behavior choices.It highlights that individuals with low AI literacy may misinterpret or overly depend on AI guidance,resulting in maladaptive health choices,while those with high AI literacy may be more likely to engage reflectively and sustain positive behaviors.The paper outlines the importance of inclusive education,user-centered design,and community-based support systems to enhance AI literacy for digitally marginalized groups.AI literacy may be positioned as a key determinant of health equity,better allowing for interdisciplinary strategies that empower individuals to make informed,autonomous decisions that promote both physical and mental health.
基金supported by the Spanish Ministry of Health‐Plan Nacional sobre Drogas(2023‐I024)the the Ministry of Science,Innovation and Universities/State ResearchAgency/10.13039/501100011033(PID2023-146865OB-I00)+2 种基金Generalitat Valenciana(CIAICO/2021/203)the Primary Addiction Care Research Network(RD21/0009/0005)FEDER Funds,GVA.
文摘Mesenchymal stem cell-derived extracellular vesicles have emerged as a promising form of regenerative and immunomodulatory therapy;indeed,micro(mi)RNAs contained within mesenchymal stem cell-derived extracellular vesicles modulate target gene expression and impact disease-associated pathways.Chronic alcohol consumption leads to neuroinflammation,brain damage,and impaired cognition.Evidence indicates that females are more vulnerable to alcohol-induced damage than males.While mesenchymal stem cell-derived extracellular vesicles have been studied in various neuroinflammatory conditions,their potential to counteract alcohol-induced brain damage remains unclear.In this study,we investigated whether repeated intravenous administration of mesenchymal stem cell-derived extracellular vesicles could ameliorate neuroinflammation and behavioral impairment induced by chronic alcohol consumption in female mice.Mesenchymal stem cell-derived extracellular vesicles diminished the increased binding of a micro-positron emission tomography tracer(^(18)F-FDG)when analyzing whole-brain 3D images and brain coronal sections of ethanol-treated mice.Mesenchymal stem cell-derived extracellular vesicle administration protected against ethanol-induced proinflammatory gene upregulation,cognitive dysfunction,and the conditioned rewarding effects of cocaine.MiRNA sequencing data from mesenchymal stem cell-derived extracellular vesicles revealed the elevated expression of extracellular vesicle-derived miR-483-5p and miR-140-3p in the brains of ethanol-treated female mice following mesenchymal stem cell-derived extracellular vesicle administration.In addition,mesenchymal stem cell-derived extracellular vesicles modulated the expression of pro-inflammatory-related miRNA target genes(e.g.,Socs3,Tnf,Mtor,and Atf6)in the brains of ethanol-treated female mice.These results suggest that mesenchymal stem cell-derived extracellular vesicles could function as a neuroprotective therapy to ameliorate the neuroinflammation,cognitive dysfunction,and conditioned rewarding effects of cocaine associated with chronic alcohol consumption.
文摘This paper prepared a novel as-cast W-Zr-Ti metallic ESM using high-frequency vacuum induction melting technique.The above ESM performs a typical elastic-brittle material feature and strain rate strengthening behavior.The specimens exhibit violent chemical reaction during the fracture process under the impact loading,and the size distribution of their residual debris follows Rosin-Rammler model.The dynamic fracture toughness is obtained by the fitting of debris length scale,approximately 1.87 MPa·m~(1/2).Microstructure observation on residual debris indicates that the failure process is determined by primary crack propagation under quasi-static compression,while it is affected by multiple cracks propagation in both particle and matrix in the case of dynamic impact.Impact test demonstrates that the novel energetic fragment performs brilliant penetration and combustion effect behind the front target,leading to the effective ignition of fuel tank.For the brittleness of as-cast W-ZrTi ESM,further study conducted bond-based peridynamic(BB-PD)C++computational code to simulate its fracture behavior during penetration.The BB-PD method successfully captured the fracture process and debris cloud formation of the energetic fragment.This paper explores a novel as-cast metallic ESM,and provides an available numerical avenue to the simulation of brittle energetic fragment.
基金supported by the National Natural Science Foundation of China (Nos. 52075449, 51975480)。
文摘The dissimilar 2B06 and 7B04 Al alloy joints were prepared by refill friction stir spot welding(RFSSW),and the microstructural evolution and corrosion behavior of the joints were investigated.Based on microstructural analysis,the welded joints exhibit distinct microstructural zones,including the stir zone(SZ),thermomechanically affected zone(TMAZ),and heat-affected zone(HAZ).The grain size of each zone is in the order of HAZ>TMAZ>SZ.Notably,the TMAZ and HAZ contain significantly larger secondary-phase particles compared to the SZ,with particle size in the HAZ increasing at higher rotational speeds.Electrochemical tests indicate that corrosion susceptibility follows the sequence of HAZ>TMAZ>SZ>BM,with greater sensitivity observed at increased rotational speeds.Post-corrosion mechanical performance degradation primarily arises from crevice corrosion at joint overlaps,but not from the changes in the microstructure.
文摘In the competitive retail industry of the digital era,data-driven insights into gender-specific customer behavior are essential.They support the optimization of store performance,layout design,product placement,and targeted marketing.However,existing computer vision solutions often rely on facial recognition to gather such insights,raising significant privacy and ethical concerns.To address these issues,this paper presents a privacypreserving customer analytics system through two key strategies.First,we deploy a deep learning framework using YOLOv9s,trained on the RCA-TVGender dataset.Cameras are positioned perpendicular to observation areas to reduce facial visibility while maintaining accurate gender classification.Second,we apply AES-128 encryption to customer position data,ensuring secure access and regulatory compliance.Our system achieved overall performance,with 81.5%mAP@50,77.7%precision,and 75.7%recall.Moreover,a 90-min observational study confirmed the system’s ability to generate privacy-protected heatmaps revealing distinct behavioral patterns between male and female customers.For instance,women spent more time in certain areas and showed interest in different products.These results confirm the system’s effectiveness in enabling personalized layout and marketing strategies without compromising privacy.
基金supported by the National Natural Science Foundation of China (Grant Nos.T2325004 and 52161160330)the National Natural Science Foundation of China (Grants No.12504233)+2 种基金Advanced MaterialsNational Science and Technology Major Project (Grant No.2024ZD0606900)the Talent Hub for “AI+New Materials” Basic Researchthe Key Research and Development Program of Ningbo (Grant No.2025Z088)。
文摘The functional properties of glasses are governed by their formation history and the complex relaxation processes they undergo.However,under extreme conditions,glass behaviors are still elusive.In this study,we employ simulations with varied protocols to evaluate the effectiveness of different descriptors in predicting mechanical properties across both low-and high-pressure regimes.Our findings demonstrate that conventional structural and configurational descriptors fail to correlate with the mechanical response following pressure release,whereas the activation energy descriptor exhibits robust linearity with shear modulus after correcting for pressure effects.Notably,the soft mode parameter emerges as an ideal and computationally efficient alternative for capturing this mechanical behavior.These findings provide critical insights into the influence of pressure on glassy properties,integrating the distinct features of compressed glasses into a unified theoretical framework.
基金financially supported by the National Natural Science Foundation of China(Nos.42107194,42090054,42377182)the Fundamental Research Funds for the Central Universities(No.CUGL190810)the Open Foundation of Engineering Research Center of Rock-Soil Drilling&Excavation and Protection,Ministry of Education(No.201802)。
文摘The reservoir landslide undergoes periodic saturation-drying cycles affected by reservoir fluctuation in hydropower project area,leading to the irreversible impact on the landslide materials.Sliding zone is the shearing part in formation of landslide and controls the further development of landslide.The mechanical behavior of sliding zone soil under compression is a crucial factor in the stability analysis in landslides.In this paper,the sliding zone soil from a giant landslide in the biggest hydropower project area,Three Gorges Reservoir Area,is taken as the research case.The particlesize distribution of the sliding zone soil from this landslide is studied and fractal dimension is adopted as representation.Periodic saturation-drying is introduced as the affecting factor on sliding zone soil properties.The triaxial compression test is conducted to reveal the mechanical behavior of the soil,including stress-strain behavior,elastic modulus,failure stress and strength parameters.These behavior of sliding zone soils with different fractal dimensions are studied under the effects of periodic saturation-drying cycles.The normalized stress-strain curves are displayed for further calculation.The data considering saturation-drying cycles are obtained and compared with the experimental results.
