In recent years, metallurgical slags have been increasingly used as materials for the manufacture of cement, pavement and filling material. The transport of the molten slag to the receiving pots is carried out through...In recent years, metallurgical slags have been increasingly used as materials for the manufacture of cement, pavement and filling material. The transport of the molten slag to the receiving pots is carried out through open channels. The transient and steady-state flow of a molten slag in a rectangular open channel is numerically analyzed here. For the transient flow, the Saint-Venant equations were numerically solved. For the steady-state flow, the derivatives in time and space in the Saint-Venant equations were set equal to zero and a polynomial of degree 3 is obtained whose roots are the slag height values. It was assumed that the viscosity of the slag has an Arrhenius-type behavior with temperature. Four values of temperature values, namely 1723.15, 1773.15, 1823.15, 18873.15 ˚K, and five values of the angle of inclination of the channel, namely 1, 2, 3, 4, 5 degrees, are considered. Numerical results show that the steady-state values of the height and velocity of the molten slag depend strongly on the temperature of the slag and the angle of inclination of the channel. As the slag temperature and channel angle increase, the value of the steady-state slag height decreases. The value of the steady-state slag velocity increases as the slag temperature and channel inclination angle increase.展开更多
One predator two prey system is a research topic which has both the theoretical and practical values. This paper provides a natural condition of the existence of stable positive steady-state solutions for the one pred...One predator two prey system is a research topic which has both the theoretical and practical values. This paper provides a natural condition of the existence of stable positive steady-state solutions for the one predator two prey system. Under this condition we study the existence of the positive steady-state solutions at vicinity of the triple eigenvalue by implicit function theorem, discuss the positive stable solution problem bifurcated from the semi-trivial solutions containing two positive components with the help of bifurcation and perturbation methods.展开更多
A one-dimensional stationary nonisentropic hydrodynamic model for semiconductor devices with non-constant lattice temperature is studied. This model consists of the equations for the electron density, the electron cur...A one-dimensional stationary nonisentropic hydrodynamic model for semiconductor devices with non-constant lattice temperature is studied. This model consists of the equations for the electron density, the electron current density and electron temperature, coupled with the Poisson equation of the electrostatic potential in a bounded interval supplemented with proper boundary conditions. The existence and uniqueness of a strong subsonic steady-state solution with positive particle density and positive temperature is established. The proof is based on the fixed-point arguments, the Stampacchia truncation methods, and the basic energy estimates.展开更多
A new type of high-order multi-resolution weighted essentially non-oscillatory(WENO)schemes(Zhu and Shu in J Comput Phys,375:659-683,2018)is applied to solve for steady-state problems on structured meshes.Since the cl...A new type of high-order multi-resolution weighted essentially non-oscillatory(WENO)schemes(Zhu and Shu in J Comput Phys,375:659-683,2018)is applied to solve for steady-state problems on structured meshes.Since the classical WENO schemes(Jiang and Shu in J Comput Phys,126:202-228,1996)might suffer from slight post-shock oscillations(which are responsible for the residue to hang at a truncation error level),this new type of high-order finite-difference and finite-volume multi-resolution WENO schemes is applied to control the slight post-shock oscillations and push the residue to settle down to machine zero in steady-state simulations.This new type of multi-resolution WENO schemes uses the same large stencils as that of the same order classical WENO schemes,could obtain fifth-order,seventh-order,and ninth-order in smooth regions,and could gradually degrade to first-order so as to suppress spurious oscillations near strong discontinuities.The linear weights of such new multi-resolution WENO schemes can be any positive numbers on the condition that their sum is one.This is the first time that a series of unequal-sized hierarchical central spatial stencils are used in designing high-order finitedifference and finite-volume WENO schemes for solving steady-state problems.In comparison with the classical fifth-order finite-difference and finite-volume WENO schemes,the residue of these new high-order multi-resolution WENO schemes can converge to a tiny number close to machine zero for some benchmark steady-state problems.展开更多
The steady state solution of long slender marine structures simply indicates the steady motion response to the excitation at top of the structure.It is very crucial especially for deep towing systems to find out how t...The steady state solution of long slender marine structures simply indicates the steady motion response to the excitation at top of the structure.It is very crucial especially for deep towing systems to find out how the towed body and towing cable work under certain towing speed.This paper has presented a direct algorithm using Runge-Kutta method for steady-state solution of long slender cylindrical structures and compared to the time iteration calculation;the direct algorithm spends much less time than the time-iteration scheme.Therefore, the direct algorithm proposed in this paper is quite efficient in providing credible reference for marine engineering applications.展开更多
Second-order axially moving systems are common models in the field of dynamics, such as axially moving strings, cables, and belts. In the traditional research work, it is difficult to obtain closed-form solutions for ...Second-order axially moving systems are common models in the field of dynamics, such as axially moving strings, cables, and belts. In the traditional research work, it is difficult to obtain closed-form solutions for the forced vibration when the damping effect and the coupling effect of multiple second-order models are considered.In this paper, Green's function method based on the Laplace transform is used to obtain closed-form solutions for the forced vibration of second-order axially moving systems. By taking the axially moving damping string system and multi-string system connected by springs as examples, the detailed solution methods and the analytical Green's functions of these second-order systems are given. The mode functions and frequency equations are also obtained by the obtained Green's functions. The reliability and convenience of the results are verified by several examples. This paper provides a systematic analytical method for the dynamic analysis of second-order axially moving systems, and the obtained Green's functions are applicable to different second-order systems rather than just string systems. In addition, the work of this paper also has positive significance for the study on the forced vibration of high-order systems.展开更多
In this paper, we design high-order Runge-Kutta discontinuous Galerkin (RKDG) methods with multi-resolution weighted essentially non-oscillatory (multi-resolution WENO) limiters to compute compressible steady-state pr...In this paper, we design high-order Runge-Kutta discontinuous Galerkin (RKDG) methods with multi-resolution weighted essentially non-oscillatory (multi-resolution WENO) limiters to compute compressible steady-state problems on triangular meshes. A troubled cell indicator extended from structured meshes to unstructured meshes is constructed to identify triangular cells in which the application of the limiting procedures is required. In such troubled cells, the multi-resolution WENO limiting methods are used to the hierarchical L^(2) projection polynomial sequence of the DG solution. Through using the RKDG methods with multi-resolution WENO limiters, the optimal high-order accuracy can be gradually reduced to first-order in the triangular troubled cells, so that the shock wave oscillations can be well suppressed. In steady-state simulations on triangular meshes, the numerical residual converges to near machine zero. The proposed spatial reconstruction methods enhance the robustness of classical DG methods on triangular meshes. The good results of these RKDG methods with multi-resolution WENO limiters are verified by a series of two-dimensional steady-state problems.展开更多
BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD....BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.展开更多
Actuator faults can be critical in turbofan engines as they can lead to stall,surge,loss of thrust and failure of speed control.Thus,fault diagnosis of gas turbine actuators has attracted considerable attention,from b...Actuator faults can be critical in turbofan engines as they can lead to stall,surge,loss of thrust and failure of speed control.Thus,fault diagnosis of gas turbine actuators has attracted considerable attention,from both academia and industry.However,the extensive literature that exists on this topic does not address identifying the severity of actuator faults and focuses mainly on actuator fault detection and isolation.In addition,previous studies of actuator fault identification have not dealt with multiple concurrent faults in real time,especially when these are accompanied by sudden failures under dynamic conditions.This study develops component-level models for fault identification in four typical actuators used in high-bypass ratio turbofan engines under both dynamic and steady-state conditions and these are then integrated with the engine performance model developed by the authors.The research results reported here present a novel method of quantifying actuator faults using dynamic effect compensation.The maximum error for each actuator is less than0.06%and 0.07%,with average computational time of less than 0.0058 s and 0.0086 s for steady-state and transient cases,respectively.These results confirm that the proposed method can accurately and efficiently identify concurrent actuator fault for an engine operating under either transient or steady-state conditions,even in the case of a sudden malfunction.The research results emonstrate the potential benefit to emergency response capabilities by introducing this method of monitoring the health of aero engines.展开更多
Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method mor...Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method more easily controls the crystallization rate and is suitable for preparing large-area per-ovskite devices.However,the residual low-conductivity iodide layer in the two-step method can affect carrier transport and device stability,and the different crystallization rates of Sn-and Pb-based per-ovskites may result in poor film quality.Therefore,Sn-Pb mixed perovskites are mainly prepared by a one-step method.Herein,a MAPb_(0.5)Sn_(0.5)I_(3)-based self-powered photodetector without a hole transport layer is fabricated by a two-step method.By adjusting the concentration of the ascorbic acid(AA)addi-tive,the final perovskite film exhibited a pure phase without residues,and the optimal device exhibited a high responsivity(0.276 A W^(-1)),large specific detectivity(2.38×10^(12) Jones),and enhanced stability.This enhancement is mainly attributed to the inhibition of Sn2+oxidation,the control of crystal growth,and the sufficient reaction between organic ammonium salts and bottom halides due to the AA-induced pore structure.展开更多
Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhan...Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhancing patient prognosis.Obviously,non-participation of asymptomatic individuals in screening programs hampers early diagnosis and may adversely affect long-term outcomes for CRC patients.In this letter,we provide a comprehensive overview of the current status of early screening practices,while also thoroughly examine the dilemmas and potential solutions associated with early screening for CRC.In response to these issues,we proffer a set of recommendations directed at governmental authorities and the general public,which focus on augmenting financial investment,establishing standardized screening protocols,advancing technological capabilities,and bolstering public awareness campaigns.The importance of collaborative efforts from various stakeholders cannot be overstated in the quest to enhance early detection rates and alleviate the societal burden of CRC.展开更多
The performance of Mg alloys is significantly influenced by the concentrations and solid solution behavior of the alloying elements.In this work,the solid solution behavior of 20 alloying elements in 190 ternary Mg al...The performance of Mg alloys is significantly influenced by the concentrations and solid solution behavior of the alloying elements.In this work,the solid solution behavior of 20 alloying elements in 190 ternary Mg alloy systems at 500℃are systematically investigated.The solid solution behavior of a set of two different alloying elements in Mg alloy systems are suggested to be classified into three categories:inclusivity,exclusivity and proportionality.Inclusivity classification indicates that the two alloying elements are inclusive inα-Mg,increasing the joint solubility of both elements.Exclusivity classification suggests that the two alloying elements have a low joint solid solubility inα-Mg,since they prefer to form stable second phases.For the proportionality classification,the solubility curve of the ternary Mg alloy systems is a straight line connecting the solubility points of the two sub-binary systems.The proposed classification theory was validated by key experiments and the calculation of formation energies.The interaction effects between alloying elements and the preference of formation of second phases are the main factors determining the solid solution behavior classifications.Based on the observed solid solution features of multi-component Mg alloys,principles for alloy design of different types of high-performance Mg alloys were proposed in this work.展开更多
Background:Isotonic crystalloids are recommended as the first choice for fluid therapy in acute pan-creatitis(AP),with normal saline(NS)and lactate Ringer’s(LR)used most often.Evidence based recom-mendations on the t...Background:Isotonic crystalloids are recommended as the first choice for fluid therapy in acute pan-creatitis(AP),with normal saline(NS)and lactate Ringer’s(LR)used most often.Evidence based recom-mendations on the type of fluid are conflicting and generally come from small single-center randomized controlled trials(RCTs).We therefore conducted a systematic review and meta-analysis to compare the effect of balanced solutions(BS)versus NS on patient-centered clinical outcomes in AP.Methods:From four databases searched up to October 2024,we included only RCTs of adult patients with AP that compared the use of BS(including LR,acetate Ringer’s,etc.)with NS.The primary out-come was the disease advances from AP to moderately severe and severe AP(MSAP/SAP).Trial sequential analyses(TSA)were conducted to control for type-I and type-II errors and Grading of Recommendations Assessment,Development,and Evaluation(GRADE)was used to assess the quality of evidence.Results:Six RCTs were identified and included,involving 260 patients treated with BS and 298 patients with NS.Patients who received the BS had less MSAP/SAP[odds ratio(OR)=0.50,95%confidence in-terval(CI):0.29 to 0.85,P=0.01,I^(2)=0%;5 studies,299 patients],reduced the need of ICU admission(OR=0.60,95%CI:0.39 to 0.93,P=0.02,I^(2)=0%;5 studies,507 patients)and shorter length of hospital stay[mean difference(MD)=-0.88,95%CI:-1.48 to-0.28,P=0.004,I^(2)=0%;6 studies,558 patients;confirmed by TSA with high certainty]compared with those who received NS.The evidence for most of the clinical outcomes was rated as moderate to low due to the risk of bias,imprecision and inconsistency.Conclusions:BS,compared with NS,was associated with improved clinical outcomes in patients with AP.However,given the moderate to low quality of evidence for most of the outcomes assessed,further trials are warranted.展开更多
In order to find closed form solutions of nonintegrable nonlinear ordinary differential equations,numerous tricks have been proposed.The goal of this short review is to explain how a theorem of Eremenko on meromorphic...In order to find closed form solutions of nonintegrable nonlinear ordinary differential equations,numerous tricks have been proposed.The goal of this short review is to explain how a theorem of Eremenko on meromorphic solutions of some nonlinear ODEs together with some classical,19th-century results,can be turned into algorithms(thus avoiding ad hoc assumptions)which provide all(as opposed to some)solutions in a precise class.To illustrate these methods,we present some new such exact solutions,physically relevant.展开更多
Morphology and growth rate of carbon dioxide hydrate on the interface between liquid carbon dioxide and humic acid solutions were studied in this work.It was found that after the growth of the hydrate film at the inte...Morphology and growth rate of carbon dioxide hydrate on the interface between liquid carbon dioxide and humic acid solutions were studied in this work.It was found that after the growth of the hydrate film at the interface,further growth of hydrate due to the suction of water in the capillary system formed between the wall of the cuvette and the end boundary of the hydrate layer occurs.Most probably,substantial effects on the formation of this capillary system may be caused by variations in reactor wall properties,for example,hydrophobic-hydrophilic balance,roughness,etc.We found,that the rate of CO_(2) hydrate film growth on the surface of the humic acid aqueous solution is 4-fold to lower in comparison with the growth rate on the surface of pure water.We suppose that this is caused by the adsorption of humic acid associates on the surface of hydrate particles and,as a consequence,by the deceleration of the diffusion of dissolved carbon dioxide to the growing hydrate particle.展开更多
In this paper,we mainly focus on a type of nonlinear Choquard equations with nonconstant potential.Under appropriate hypotheses on potential function and nonlinear terms,we prove that the above Choquard equation with ...In this paper,we mainly focus on a type of nonlinear Choquard equations with nonconstant potential.Under appropriate hypotheses on potential function and nonlinear terms,we prove that the above Choquard equation with prescribed 2-norm has some normalized solutions by introducing variational methods.展开更多
Hydrogen-enriched ironmaking presents a promising approach to mitigate coke consumption and carbon emission in blast furnace(BF)operations.This work investigated the relationship between the structural features of cok...Hydrogen-enriched ironmaking presents a promising approach to mitigate coke consumption and carbon emission in blast furnace(BF)operations.This work investigated the relationship between the structural features of cokes and their reactivity towards solution loss(SL),especially under hydrogen-enriched atmospheres.Six cokes were characterized,and their SL behaviors were examined under varying atmospheres to elucidate the effects of hydrogen enrichment.The results indicate that an increase in fixed carbon content leads to a decrease in the coke reactivity index(CRI)and an increase in coke strength after reaction(CSR),in the CO_(2) atmosphere,the CSR of coke increases from 35.76%−62.83%,while in the 90CO_(2)/10H_(2) atmosphere,the CSR of coke increases from 65.67%−84.09%.There is a good linear relationship between CRI and microcrystalline structure parameters of coke.Cokes with larger crystalline size,lower amorphous content,and smaller optical texture index(OTI)values show enhanced resistance to degradation and maintain structural integrity in BF.Kinetic analysis performed with the shifted-modified-random pore model(S-MRPM)reveals that alterations in pore structure and intrinsic mineral composition significantly influence the reaction rate.The introduction of a small amount of water vapor raises SL rates,whereas a minor addition of hydrogen(<10%)decelerates SL due to its incomplete conversion to water vapor and the reduced partial pressure of the gasifying agent.Thermodynamic calculations also indicate that the introduced hydrogen does not convert into the same fraction of water vapor.The shift from chemical reaction control to gas diffusion control as the rate-determining step with rising temperatures during SL process was confirmed,and the introduction of hydrogen does not notably alter SL behavior.This result demonstrated that introducing a small amount of hydrogen(<10%)can mitigate SL rates,thereby enhancing coke strength and reducing coke consumption and carbon emissions.展开更多
The article studies the evolutionary dynamics of two-population two-strategy game models with and without impulses. First, the payment matrix is given and two evolutionary dynamics models are established by adding sto...The article studies the evolutionary dynamics of two-population two-strategy game models with and without impulses. First, the payment matrix is given and two evolutionary dynamics models are established by adding stochastic and impulse. For the stochastic model without impulses, the existence and uniqueness of solution, and the existence of positive periodic solutions are proved, and a sufficient condition for strategy extinction is given. For the stochastic model with impulses, the existence of positive periodic solutions is proved. Numerical results show that noise and impulses directly affect the model, but the periodicity of the model does not change.展开更多
In this paper,we study the existence of least energy solutions for the following nonlinear fractional Schrodinger–Poisson system{(−∆)^(s)u+V(x)u+φu=f(u)in R^(3),(−∆)^(t)φ=u^(2)in R^(3),where s∈(3/4,1),t∈(0,1).Und...In this paper,we study the existence of least energy solutions for the following nonlinear fractional Schrodinger–Poisson system{(−∆)^(s)u+V(x)u+φu=f(u)in R^(3),(−∆)^(t)φ=u^(2)in R^(3),where s∈(3/4,1),t∈(0,1).Under some assumptions on V(x)and f,using Nehari–Pohozaev identity and the arguments of Brezis–Nirenberg,the monotonic trick and global compactness lemma,we prove the existence of a nontrivial least energy solution.展开更多
文摘In recent years, metallurgical slags have been increasingly used as materials for the manufacture of cement, pavement and filling material. The transport of the molten slag to the receiving pots is carried out through open channels. The transient and steady-state flow of a molten slag in a rectangular open channel is numerically analyzed here. For the transient flow, the Saint-Venant equations were numerically solved. For the steady-state flow, the derivatives in time and space in the Saint-Venant equations were set equal to zero and a polynomial of degree 3 is obtained whose roots are the slag height values. It was assumed that the viscosity of the slag has an Arrhenius-type behavior with temperature. Four values of temperature values, namely 1723.15, 1773.15, 1823.15, 18873.15 ˚K, and five values of the angle of inclination of the channel, namely 1, 2, 3, 4, 5 degrees, are considered. Numerical results show that the steady-state values of the height and velocity of the molten slag depend strongly on the temperature of the slag and the angle of inclination of the channel. As the slag temperature and channel angle increase, the value of the steady-state slag height decreases. The value of the steady-state slag velocity increases as the slag temperature and channel inclination angle increase.
基金This work is supported by National Science Foundation of China and the Fundes of Institute of Math (opened) Academic Sinica.
文摘One predator two prey system is a research topic which has both the theoretical and practical values. This paper provides a natural condition of the existence of stable positive steady-state solutions for the one predator two prey system. Under this condition we study the existence of the positive steady-state solutions at vicinity of the triple eigenvalue by implicit function theorem, discuss the positive stable solution problem bifurcated from the semi-trivial solutions containing two positive components with the help of bifurcation and perturbation methods.
基金the Educational Department of Hubei province(Q200628002)the National Science Foundation of China(10701057)
文摘A one-dimensional stationary nonisentropic hydrodynamic model for semiconductor devices with non-constant lattice temperature is studied. This model consists of the equations for the electron density, the electron current density and electron temperature, coupled with the Poisson equation of the electrostatic potential in a bounded interval supplemented with proper boundary conditions. The existence and uniqueness of a strong subsonic steady-state solution with positive particle density and positive temperature is established. The proof is based on the fixed-point arguments, the Stampacchia truncation methods, and the basic energy estimates.
基金supported by the National Natural Science Foundation of China(Grant No.11872210)supported by the National Science Foundation(Grant No.DMS-1719410)
文摘A new type of high-order multi-resolution weighted essentially non-oscillatory(WENO)schemes(Zhu and Shu in J Comput Phys,375:659-683,2018)is applied to solve for steady-state problems on structured meshes.Since the classical WENO schemes(Jiang and Shu in J Comput Phys,126:202-228,1996)might suffer from slight post-shock oscillations(which are responsible for the residue to hang at a truncation error level),this new type of high-order finite-difference and finite-volume multi-resolution WENO schemes is applied to control the slight post-shock oscillations and push the residue to settle down to machine zero in steady-state simulations.This new type of multi-resolution WENO schemes uses the same large stencils as that of the same order classical WENO schemes,could obtain fifth-order,seventh-order,and ninth-order in smooth regions,and could gradually degrade to first-order so as to suppress spurious oscillations near strong discontinuities.The linear weights of such new multi-resolution WENO schemes can be any positive numbers on the condition that their sum is one.This is the first time that a series of unequal-sized hierarchical central spatial stencils are used in designing high-order finitedifference and finite-volume WENO schemes for solving steady-state problems.In comparison with the classical fifth-order finite-difference and finite-volume WENO schemes,the residue of these new high-order multi-resolution WENO schemes can converge to a tiny number close to machine zero for some benchmark steady-state problems.
基金the National Natural Science Foundation of China(Nos.51009092 and 50909061)the Doctoral Foundation of Education Ministry of China (No.20090073120013)the National High Technology Research and Development Program (863) of China (No.2008AA092301-1)
文摘The steady state solution of long slender marine structures simply indicates the steady motion response to the excitation at top of the structure.It is very crucial especially for deep towing systems to find out how the towed body and towing cable work under certain towing speed.This paper has presented a direct algorithm using Runge-Kutta method for steady-state solution of long slender cylindrical structures and compared to the time iteration calculation;the direct algorithm spends much less time than the time-iteration scheme.Therefore, the direct algorithm proposed in this paper is quite efficient in providing credible reference for marine engineering applications.
基金Project supported by the National Natural Science Foundation of China (No. 12272323)。
文摘Second-order axially moving systems are common models in the field of dynamics, such as axially moving strings, cables, and belts. In the traditional research work, it is difficult to obtain closed-form solutions for the forced vibration when the damping effect and the coupling effect of multiple second-order models are considered.In this paper, Green's function method based on the Laplace transform is used to obtain closed-form solutions for the forced vibration of second-order axially moving systems. By taking the axially moving damping string system and multi-string system connected by springs as examples, the detailed solution methods and the analytical Green's functions of these second-order systems are given. The mode functions and frequency equations are also obtained by the obtained Green's functions. The reliability and convenience of the results are verified by several examples. This paper provides a systematic analytical method for the dynamic analysis of second-order axially moving systems, and the obtained Green's functions are applicable to different second-order systems rather than just string systems. In addition, the work of this paper also has positive significance for the study on the forced vibration of high-order systems.
基金supported by the NSFC Grant No.11872210 and Grant No.MCMS-I-0120G01Chi-Wang Shu:Research is supported by the AFOSR Grant FA9550-20-1-0055 and the NSF Grant DMS-2010107Jianxian Qiu:Research is supported by the NSFC Grant No.12071392.
文摘In this paper, we design high-order Runge-Kutta discontinuous Galerkin (RKDG) methods with multi-resolution weighted essentially non-oscillatory (multi-resolution WENO) limiters to compute compressible steady-state problems on triangular meshes. A troubled cell indicator extended from structured meshes to unstructured meshes is constructed to identify triangular cells in which the application of the limiting procedures is required. In such troubled cells, the multi-resolution WENO limiting methods are used to the hierarchical L^(2) projection polynomial sequence of the DG solution. Through using the RKDG methods with multi-resolution WENO limiters, the optimal high-order accuracy can be gradually reduced to first-order in the triangular troubled cells, so that the shock wave oscillations can be well suppressed. In steady-state simulations on triangular meshes, the numerical residual converges to near machine zero. The proposed spatial reconstruction methods enhance the robustness of classical DG methods on triangular meshes. The good results of these RKDG methods with multi-resolution WENO limiters are verified by a series of two-dimensional steady-state problems.
基金Supported by Science and Technology Department of Sichuan Province,No.2020YFS0376National Natural Science Foundation of China,No.81900599Science and Technology Program of Hospital of TCM,Southwest Medical University,No.2022-CXTD-01.
文摘BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.
基金support by the National Natural Science Foundation of China(Grant No.52402520)。
文摘Actuator faults can be critical in turbofan engines as they can lead to stall,surge,loss of thrust and failure of speed control.Thus,fault diagnosis of gas turbine actuators has attracted considerable attention,from both academia and industry.However,the extensive literature that exists on this topic does not address identifying the severity of actuator faults and focuses mainly on actuator fault detection and isolation.In addition,previous studies of actuator fault identification have not dealt with multiple concurrent faults in real time,especially when these are accompanied by sudden failures under dynamic conditions.This study develops component-level models for fault identification in four typical actuators used in high-bypass ratio turbofan engines under both dynamic and steady-state conditions and these are then integrated with the engine performance model developed by the authors.The research results reported here present a novel method of quantifying actuator faults using dynamic effect compensation.The maximum error for each actuator is less than0.06%and 0.07%,with average computational time of less than 0.0058 s and 0.0086 s for steady-state and transient cases,respectively.These results confirm that the proposed method can accurately and efficiently identify concurrent actuator fault for an engine operating under either transient or steady-state conditions,even in the case of a sudden malfunction.The research results emonstrate the potential benefit to emergency response capabilities by introducing this method of monitoring the health of aero engines.
基金supported by the National Natural Science Foun-dation of China(Nos.52025028,52332008,52372214,52202273,and U22A20137)the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions.
文摘Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method more easily controls the crystallization rate and is suitable for preparing large-area per-ovskite devices.However,the residual low-conductivity iodide layer in the two-step method can affect carrier transport and device stability,and the different crystallization rates of Sn-and Pb-based per-ovskites may result in poor film quality.Therefore,Sn-Pb mixed perovskites are mainly prepared by a one-step method.Herein,a MAPb_(0.5)Sn_(0.5)I_(3)-based self-powered photodetector without a hole transport layer is fabricated by a two-step method.By adjusting the concentration of the ascorbic acid(AA)addi-tive,the final perovskite film exhibited a pure phase without residues,and the optimal device exhibited a high responsivity(0.276 A W^(-1)),large specific detectivity(2.38×10^(12) Jones),and enhanced stability.This enhancement is mainly attributed to the inhibition of Sn2+oxidation,the control of crystal growth,and the sufficient reaction between organic ammonium salts and bottom halides due to the AA-induced pore structure.
文摘Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhancing patient prognosis.Obviously,non-participation of asymptomatic individuals in screening programs hampers early diagnosis and may adversely affect long-term outcomes for CRC patients.In this letter,we provide a comprehensive overview of the current status of early screening practices,while also thoroughly examine the dilemmas and potential solutions associated with early screening for CRC.In response to these issues,we proffer a set of recommendations directed at governmental authorities and the general public,which focus on augmenting financial investment,establishing standardized screening protocols,advancing technological capabilities,and bolstering public awareness campaigns.The importance of collaborative efforts from various stakeholders cannot be overstated in the quest to enhance early detection rates and alleviate the societal burden of CRC.
基金financially supported by National Natural Science Foundation of China(grant numbers:52171100,U20A20234)National Key R&D Program of China(grant number:2021YFB3701100)。
文摘The performance of Mg alloys is significantly influenced by the concentrations and solid solution behavior of the alloying elements.In this work,the solid solution behavior of 20 alloying elements in 190 ternary Mg alloy systems at 500℃are systematically investigated.The solid solution behavior of a set of two different alloying elements in Mg alloy systems are suggested to be classified into three categories:inclusivity,exclusivity and proportionality.Inclusivity classification indicates that the two alloying elements are inclusive inα-Mg,increasing the joint solubility of both elements.Exclusivity classification suggests that the two alloying elements have a low joint solid solubility inα-Mg,since they prefer to form stable second phases.For the proportionality classification,the solubility curve of the ternary Mg alloy systems is a straight line connecting the solubility points of the two sub-binary systems.The proposed classification theory was validated by key experiments and the calculation of formation energies.The interaction effects between alloying elements and the preference of formation of second phases are the main factors determining the solid solution behavior classifications.Based on the observed solid solution features of multi-component Mg alloys,principles for alloy design of different types of high-performance Mg alloys were proposed in this work.
文摘Background:Isotonic crystalloids are recommended as the first choice for fluid therapy in acute pan-creatitis(AP),with normal saline(NS)and lactate Ringer’s(LR)used most often.Evidence based recom-mendations on the type of fluid are conflicting and generally come from small single-center randomized controlled trials(RCTs).We therefore conducted a systematic review and meta-analysis to compare the effect of balanced solutions(BS)versus NS on patient-centered clinical outcomes in AP.Methods:From four databases searched up to October 2024,we included only RCTs of adult patients with AP that compared the use of BS(including LR,acetate Ringer’s,etc.)with NS.The primary out-come was the disease advances from AP to moderately severe and severe AP(MSAP/SAP).Trial sequential analyses(TSA)were conducted to control for type-I and type-II errors and Grading of Recommendations Assessment,Development,and Evaluation(GRADE)was used to assess the quality of evidence.Results:Six RCTs were identified and included,involving 260 patients treated with BS and 298 patients with NS.Patients who received the BS had less MSAP/SAP[odds ratio(OR)=0.50,95%confidence in-terval(CI):0.29 to 0.85,P=0.01,I^(2)=0%;5 studies,299 patients],reduced the need of ICU admission(OR=0.60,95%CI:0.39 to 0.93,P=0.02,I^(2)=0%;5 studies,507 patients)and shorter length of hospital stay[mean difference(MD)=-0.88,95%CI:-1.48 to-0.28,P=0.004,I^(2)=0%;6 studies,558 patients;confirmed by TSA with high certainty]compared with those who received NS.The evidence for most of the clinical outcomes was rated as moderate to low due to the risk of bias,imprecision and inconsistency.Conclusions:BS,compared with NS,was associated with improved clinical outcomes in patients with AP.However,given the moderate to low quality of evidence for most of the outcomes assessed,further trials are warranted.
基金partially supported by RGC(No.17307420)supported by NSFC(No.12471077)。
文摘In order to find closed form solutions of nonintegrable nonlinear ordinary differential equations,numerous tricks have been proposed.The goal of this short review is to explain how a theorem of Eremenko on meromorphic solutions of some nonlinear ODEs together with some classical,19th-century results,can be turned into algorithms(thus avoiding ad hoc assumptions)which provide all(as opposed to some)solutions in a precise class.To illustrate these methods,we present some new such exact solutions,physically relevant.
基金supported by the Russian Science Foundation(23-29-00830).
文摘Morphology and growth rate of carbon dioxide hydrate on the interface between liquid carbon dioxide and humic acid solutions were studied in this work.It was found that after the growth of the hydrate film at the interface,further growth of hydrate due to the suction of water in the capillary system formed between the wall of the cuvette and the end boundary of the hydrate layer occurs.Most probably,substantial effects on the formation of this capillary system may be caused by variations in reactor wall properties,for example,hydrophobic-hydrophilic balance,roughness,etc.We found,that the rate of CO_(2) hydrate film growth on the surface of the humic acid aqueous solution is 4-fold to lower in comparison with the growth rate on the surface of pure water.We suppose that this is caused by the adsorption of humic acid associates on the surface of hydrate particles and,as a consequence,by the deceleration of the diffusion of dissolved carbon dioxide to the growing hydrate particle.
基金Supported by the National Natural Science Foundation of China(11671403,11671236,12101192)Henan Provincial General Natural Science Foundation Project(232300420113)。
文摘In this paper,we mainly focus on a type of nonlinear Choquard equations with nonconstant potential.Under appropriate hypotheses on potential function and nonlinear terms,we prove that the above Choquard equation with prescribed 2-norm has some normalized solutions by introducing variational methods.
基金supported by National Natural Science Foundation of China(22178002,22178001)Natural Science Foundation of Anhui Province(2308085Y19)Excellent Youth Research Project of Anhui Provincial Department of Education(2022AH030045).
文摘Hydrogen-enriched ironmaking presents a promising approach to mitigate coke consumption and carbon emission in blast furnace(BF)operations.This work investigated the relationship between the structural features of cokes and their reactivity towards solution loss(SL),especially under hydrogen-enriched atmospheres.Six cokes were characterized,and their SL behaviors were examined under varying atmospheres to elucidate the effects of hydrogen enrichment.The results indicate that an increase in fixed carbon content leads to a decrease in the coke reactivity index(CRI)and an increase in coke strength after reaction(CSR),in the CO_(2) atmosphere,the CSR of coke increases from 35.76%−62.83%,while in the 90CO_(2)/10H_(2) atmosphere,the CSR of coke increases from 65.67%−84.09%.There is a good linear relationship between CRI and microcrystalline structure parameters of coke.Cokes with larger crystalline size,lower amorphous content,and smaller optical texture index(OTI)values show enhanced resistance to degradation and maintain structural integrity in BF.Kinetic analysis performed with the shifted-modified-random pore model(S-MRPM)reveals that alterations in pore structure and intrinsic mineral composition significantly influence the reaction rate.The introduction of a small amount of water vapor raises SL rates,whereas a minor addition of hydrogen(<10%)decelerates SL due to its incomplete conversion to water vapor and the reduced partial pressure of the gasifying agent.Thermodynamic calculations also indicate that the introduced hydrogen does not convert into the same fraction of water vapor.The shift from chemical reaction control to gas diffusion control as the rate-determining step with rising temperatures during SL process was confirmed,and the introduction of hydrogen does not notably alter SL behavior.This result demonstrated that introducing a small amount of hydrogen(<10%)can mitigate SL rates,thereby enhancing coke strength and reducing coke consumption and carbon emissions.
基金Supported by the National Natural Science Foundation of China(10671182)。
文摘The article studies the evolutionary dynamics of two-population two-strategy game models with and without impulses. First, the payment matrix is given and two evolutionary dynamics models are established by adding stochastic and impulse. For the stochastic model without impulses, the existence and uniqueness of solution, and the existence of positive periodic solutions are proved, and a sufficient condition for strategy extinction is given. For the stochastic model with impulses, the existence of positive periodic solutions is proved. Numerical results show that noise and impulses directly affect the model, but the periodicity of the model does not change.
基金Supported by NSFC(No.12561023)partly by the Provincial Natural Science Foundation of Jiangxi,China(Nos.20232BAB201001,20202BAB211004)。
文摘In this paper,we study the existence of least energy solutions for the following nonlinear fractional Schrodinger–Poisson system{(−∆)^(s)u+V(x)u+φu=f(u)in R^(3),(−∆)^(t)φ=u^(2)in R^(3),where s∈(3/4,1),t∈(0,1).Under some assumptions on V(x)and f,using Nehari–Pohozaev identity and the arguments of Brezis–Nirenberg,the monotonic trick and global compactness lemma,we prove the existence of a nontrivial least energy solution.
文摘In this paper,by using the method of Lyapunov-Schmidt reduction,we obtain the existence of multi-bump solutions for planar Schrödinger-Poisson system.