Objective To determine the prevalence of lumbar spondylolysis(LS)and the proportion of spondylolytic spondylolisthesis(SS)in China,and to evaluate the musculoskeletal status of patients with LS and SS.Methods Spine Co...Objective To determine the prevalence of lumbar spondylolysis(LS)and the proportion of spondylolytic spondylolisthesis(SS)in China,and to evaluate the musculoskeletal status of patients with LS and SS.Methods Spine Computed Tomography(CT)images were collected from community populations aged 40 and above in a nationwide multi-center project.LS was diagnosed,and SS was graded by an experienced radiologist.Bone mineral density(BMD)and paraspinal muscle parameters were quantified based on CT images.Results One hundred and seventeen patients of a total of 3,317 individuals were diagnosed with LS,corresponding to a prevalence rate of 3.53%.63 of the 1,214 males(5.18%)and 54 of the 2,103 females(2.57%)were diagnosed with LS.SS occurred in 64/121 vertebrae(52.89%).BMD was not associated with LS(P=0.341).The L5 extensor paraspinal muscle density was higher in the LS group than in the non-LS group.In the LS group,patients with SS had a smaller L5 paraspinal extensor muscle cross-sectional area than those without SS(P=0.003).Conclusion The prevalence of LS in Chinese adults was 3.53%,with prevalence rates of 5.18%in males and 2.57%in females.Patients with LS have higher muscle density,whereas those with SS have smaller muscle cross-sectional areas at the L5 level.展开更多
基金Funding National Key R&D Program of China(2021YFC2501701,2021YFC2501703)Beijing Jishuitan Hospital Scientific Research Fund(QN202404)+1 种基金Beijing Municipal Health Commission(BJRITO-RDP-2023)Beijing Municipal Public Welfare Development and Reform Pilot Project for Medical Research Institutes(JYY2023-8).
文摘Objective To determine the prevalence of lumbar spondylolysis(LS)and the proportion of spondylolytic spondylolisthesis(SS)in China,and to evaluate the musculoskeletal status of patients with LS and SS.Methods Spine Computed Tomography(CT)images were collected from community populations aged 40 and above in a nationwide multi-center project.LS was diagnosed,and SS was graded by an experienced radiologist.Bone mineral density(BMD)and paraspinal muscle parameters were quantified based on CT images.Results One hundred and seventeen patients of a total of 3,317 individuals were diagnosed with LS,corresponding to a prevalence rate of 3.53%.63 of the 1,214 males(5.18%)and 54 of the 2,103 females(2.57%)were diagnosed with LS.SS occurred in 64/121 vertebrae(52.89%).BMD was not associated with LS(P=0.341).The L5 extensor paraspinal muscle density was higher in the LS group than in the non-LS group.In the LS group,patients with SS had a smaller L5 paraspinal extensor muscle cross-sectional area than those without SS(P=0.003).Conclusion The prevalence of LS in Chinese adults was 3.53%,with prevalence rates of 5.18%in males and 2.57%in females.Patients with LS have higher muscle density,whereas those with SS have smaller muscle cross-sectional areas at the L5 level.
