Five new spirostanol saponins(1−5)and seven known compounds(6−12)were isolated from the n-butanol fraction of 75%ethanol extract of Allii Macrostemonis Bulbus.The identification and structural elucidation of all the i...Five new spirostanol saponins(1−5)and seven known compounds(6−12)were isolated from the n-butanol fraction of 75%ethanol extract of Allii Macrostemonis Bulbus.The identification and structural elucidation of all the isolates were performed through extensive 1D and 2D NMR experiments,HR-ESI-MS data analysis and comparisons with literature values.Antioxidant evaluation showed that compounds 6−11 exhibited certain scavenging effects on ABTS radical,where compounds 6,7 and 11 had IC50 values of 0.208,0.057 and 0.014 mg·mL−1,respectively.展开更多
基金Jilin Science and Technology Development Program(No.20200404023YY).
文摘Five new spirostanol saponins(1−5)and seven known compounds(6−12)were isolated from the n-butanol fraction of 75%ethanol extract of Allii Macrostemonis Bulbus.The identification and structural elucidation of all the isolates were performed through extensive 1D and 2D NMR experiments,HR-ESI-MS data analysis and comparisons with literature values.Antioxidant evaluation showed that compounds 6−11 exhibited certain scavenging effects on ABTS radical,where compounds 6,7 and 11 had IC50 values of 0.208,0.057 and 0.014 mg·mL−1,respectively.
