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ANALYSIS FOR AIRCRAFT TAXIING AT VARIABLE VELOCITY ON UNEVENNESS RUNWAY BY THE POWER SPECTRAL DENSITY METHOD 被引量:3
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作者 聂宏 W.Kortuüm 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2000年第1期64-70,共7页
In this paper a novel approach for the analysis of non stationary response of aircraft landing gear taxiing over an unevenness runway at variable velocity is explored, which is based on the power spectral density met... In this paper a novel approach for the analysis of non stationary response of aircraft landing gear taxiing over an unevenness runway at variable velocity is explored, which is based on the power spectral density method. A concerned analytical landing gear model for simulating actual aircraft taxiing is formulated. The equivalent linearization results obtained by probabilistic method are inducted to treat landing gear non linear parameters such as shock absorber air spring force, hydraulic damping and Coulomb friction, tire stiffness and damping. The power spectral density for non stationary analysis is obtained via variable substitution and then Fourier transform. A representative response quantity, the overload of the aircraft gravity center, is analyzed. The frequency response function of the gravity overload is derived. The case study demonstrates that under the same reached velocity the root mean square of the gravity acceleration response from constant acceleration taxiing is smaller than that from constant velocity taxiing and the root mean square of the gravity acceleration response from lower acceleration taxiing is greater than that from higher acceleration. 展开更多
关键词 aircraft landing gear random vibration non stationary response power spectral density equivalent linearization
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ESTIMATION OF THE NUMBER OF CORRELATED SOURCES WITH COMMON FREQUENCIES BASED ON POWER SPECTRAL DENSITY 被引量:5
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作者 LI Ning SHI Tielin 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2007年第4期88-93,共6页
Blind source separation and estimation of the number of sources usually demand that the number of sensors should be greater than or equal to that of the sources,which,however,is very difficult to satisfy for the compl... Blind source separation and estimation of the number of sources usually demand that the number of sensors should be greater than or equal to that of the sources,which,however,is very difficult to satisfy for the complex systems.A new estimating method based on power spectral density(PSD)is presented.When the relation between the number of sensors and that of sources is unknown,the PSD matrix is first obtained by the ratio of PSD of the observation signals,and then the bound of the number of correlated sources with common frequencies can be estimated by comparing every column vector of PSD matrix.The effectiveness of the proposed method is verified by theoretical analysis and experiments,and the influence of noise on the estimation of number of source is simulated. 展开更多
关键词 Blind signal Number of sources Power spectral density
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Roughness evaluation of three-dimensional asphalt pavement based on two-dimensional power spectral density 被引量:2
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作者 Ding Zhike Xu Feiyun Zhao Xun 《Journal of Southeast University(English Edition)》 EI CAS 2022年第4期401-407,共7页
To solve the problem of the lack of comprehensive evaluation of three-dimensional(3D)asphalt pavement roughness,a method for evaluating the asphalt pavement roughness is proposed based on two-dimensional(2D)power spec... To solve the problem of the lack of comprehensive evaluation of three-dimensional(3D)asphalt pavement roughness,a method for evaluating the asphalt pavement roughness is proposed based on two-dimensional(2D)power spectral density(PSD).By calculating the 2D PSD of a 3D asphalt pavement and converting it into the longitudinal average asphalt pavement PSD,the relationship between the evaluation method of the 3D asphalt pavement roughness and the current evaluation standard of roughness is established.Combined with the road-fitting formula used in international standards,the elevation data of the A,B,C,and D grades of the 3D asphalt pavement are simulated by the harmonic superposition method.According to the proposed method,the longitudinal PSD of each level of simulated asphalt pavement is calculated and compared with the standard spectral line of each pavement level.This approach verifies the effectiveness of the proposed method in evaluating the roughness of the 3D asphalt pavement.Compared with the PSD of a certain horizontal profile elevation,it is verified that the fluctuation amplitude of the spectral line calculated by the proposed method is greatly improved.The results show that the proposed method can evaluate the roughness of asphalt pavements more comprehensively and accurately and has strong practicability. 展开更多
关键词 ROUGHNESS power spectral density three-dimensional asphalt pavement
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Orbital reference frame estimation with power spectral density constraints for drag-free satellites 被引量:1
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作者 Zhang Yonghe Wang Yamin +1 位作者 Mao Qingyun Liang Xuwen 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2016年第6期1721-1729,共9页
The drag-free satellites are widely used in the field of fundamental science as they enable the high-precision measurement in pure gravity fields. This paper investigates the estimation of local orbital reference fram... The drag-free satellites are widely used in the field of fundamental science as they enable the high-precision measurement in pure gravity fields. This paper investigates the estimation of local orbital reference frame(LORF) for drag-free satellites. An approach, taking account of the combination of the minimum estimation error and power spectral density(PSD) constraint in frequency domain, is proposed. Firstly, the relationship between eigenvalues of estimator and transfer function is built to analyze the suppression and amplification effect on input signals and obtain the eigenvalue range. Secondly, an optimization model for state estimator design with minimum estimation error in time domain and PSD constraint in frequency domain is established. It is solved by the sequential quadratic programming(SQP) algorithm. Finally, the orbital reference frame estimation of low-earth-orbit satellite is taken as an example, and the estimator of minimum variance with PSD constraint is designed and analyzed using the method proposed in this paper. 展开更多
关键词 Drag-free satellite Orbital reference frame Power spectral density State estimation Transfer function
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EVALUATION OF POWER SPECTRAL DENSITY OF PASSIVE INTERMODULATION DISTORTION IN HIGH-POWER COMMUNICATION SATELLITE SYSTEMS 被引量:1
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作者 ZhangShiquan GeDebiao 《Journal of Electronics(China)》 2005年第2期181-184,共4页
In order to analyze the deleterious effects of Passive InterModulation (PIM) on high power communication satellite systems, the basic concept of PIM is introduced, and an equation for the power spectral density of the... In order to analyze the deleterious effects of Passive InterModulation (PIM) on high power communication satellite systems, the basic concept of PIM is introduced, and an equation for the power spectral density of the n-th order PIM distortion insuch systems is derived by applying flat signal-power spectrum assumption and Fourier transform method. It is indicated that PIM level generally decreases with order and the lowest frequency receive channel in the receive band is the channel of most affected by PIM interference. 展开更多
关键词 Passive InterModulation(PIM) Power spectral density Fourier transform Communication satellite
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The Wavefront Power Spectral Density Measurement of Aspheric Lens with Long Focal-Length Using a Computer-Generated Hologram 被引量:1
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作者 Xiaohong Wei Kaiyuan Xu Ang Liu 《Optics and Photonics Journal》 CAS 2022年第11期225-233,共9页
To ensure the performance of the optical system, the machining accuracy of lens with long focal lengths is required to ensure the image quality. A new method for lens transmission wavefront power spectral density (PSD... To ensure the performance of the optical system, the machining accuracy of lens with long focal lengths is required to ensure the image quality. A new method for lens transmission wavefront power spectral density (PSD) in mid-frequency domain measurement using binary phase computer-generated hologram (CGH) is presented. This technique is widely applicable and is particularly useful for measuring large-size lenses with long focal lengths. A comparison experiment of the CGH measurement with results from a Fizeau sphere interferometry method is carried out to verify the accuracy and convenience of the measurement. Furthermore, measurement uncertainty due to CGH fabrication process is analysed. Analysis of the CGH test showed the overall accuracy of less than 1 nm RMS for a sphere lens with over 30 m focal length and Φ410 mm clear aperture. CGH can provide reference spheres with high precision, in the meantime greatly shorten air space, thus reducing the effect of vibration and air turbulence, therefore is of great importance for lens transmission wavefront PSD measurement. The realization of high precision, high efficiency and nondestructive testing of long focal-lens wavefront PSD ensure the ultra-precision and certainty level of machining, hence improving the comprehensive performance of the optical system. 展开更多
关键词 Power spectral density Measurement INTERFEROMETRY CGH
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High dynamic synchronization algorithm based on cyclic spectral density
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作者 高玉龙 陈艳萍 +2 位作者 王骐 沙学军 张中兆 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2011年第3期121-124,共4页
A new high dynamic synchronization algorithm using cyclic spectral density was presented according to the theories of cyclic spectral density and its anti-interface and anti-noise properties.The closed forms of freque... A new high dynamic synchronization algorithm using cyclic spectral density was presented according to the theories of cyclic spectral density and its anti-interface and anti-noise properties.The closed forms of frequency error and phase error were obtained,and their performances were analyzed.The in-phase signal throw costas loop was normalized to obtain a cosine signal.Cyclic spectral density of the cosine signal of was computed to obtain the frequency error and the phase error and then results were put into NCO to synchronize.Finally,the performance of the presented algorithms was compared with the conventional algorithms by virtue of simulations,and the simulation results proved the correctness and the superiority of the new algorithms. 展开更多
关键词 cyclic spectral density frequency-locked phase-locked loop high dynamic synchronization strip sneetral correlation
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Nonlinear distortion analysis for multisine excitation constrained by power spectral density
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作者 ZHOU Kun-li QU Ji-feng ZHOU Zhen-yu 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2016年第4期350-357,共8页
Nonlinear distortion introduced by an amplifier when subjected to a multisine excitation decreases the measurement accuracy in many metrological and measurement areas. In this paper, we performed qualitative and quant... Nonlinear distortion introduced by an amplifier when subjected to a multisine excitation decreases the measurement accuracy in many metrological and measurement areas. In this paper, we performed qualitative and quantitative analyses of the nonlinear distortion with the multisine excitations constrained by a constant power spectral density. We present the numerical results with respect to different tone spacings,nonlinear orders, harmonic phases and tone distributions. Moreover, three as-pects of contributions are made to further reveal the distortion mechanism. First, we find that the type Ⅱ components for Schr- oeder-phase multisines distribute uniformly but not all in anti-phase to the type I components for the second order nonlinearity. Second,we simulate the variance of the type I and Ⅱ components and their summation to explain the principle of reducing the type Ⅱ distortion by averaging the results obtained using multiple realizations of random-phase multisines. Third, we observe a special distortion distribution mechanism for the Schroeder-phase multisine excitation The results contribute to a better estima-tion and understanding of the nonlinear distortion. 展开更多
关键词 multisine excitation nonlinear distortion power spectral density type I and contributions
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Spectral Density Estimation of Continuous Time Series
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作者 Ahmed Elhassanein 《Applied Mathematics》 2016年第17期2140-2148,共9页
This paper studies spectral density estimation of a strictly stationary r-vector valued continuous time series including missing observations. The finite Fourier transform is constructed in L-joint segments of observa... This paper studies spectral density estimation of a strictly stationary r-vector valued continuous time series including missing observations. The finite Fourier transform is constructed in L-joint segments of observations. The modified periodogram is defined and smoothed to estimate the spectral density matrix. We explore the properties of the proposed estimator. Asymptotic distribution is discussed. 展开更多
关键词 Joint Segments of Observations Modified Periodograms spectral density Matrix Wishart Matrix
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Three-dimensional characteristics and spectral model of the roughness of airport runway surface
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作者 Shifu Liu Kaiying Mao +2 位作者 Tianxin Hou Jianming Ling Zhongyu Sun 《Journal of Road Engineering》 2026年第1期23-33,共11页
Runway surface roughness significantly influences aircraft vibrations during takeoff and landing,affecting both flight safety and pavement durability.Aircraft operate at high speeds and wide gear spans,making them sen... Runway surface roughness significantly influences aircraft vibrations during takeoff and landing,affecting both flight safety and pavement durability.Aircraft operate at high speeds and wide gear spans,making them sensitive to long-wavelength(15–120 m)and lateral irregularities,which are often overlooked in traditional roughness models.This study aims to construct a three-dimensional runway roughness modeling framework integrating"precise detection-spectrum analysis-spatial reconstruction"in response to this issue.Combining the elevation data of 37 runways(5 asphalt runways and 32 cement runways)measured by a vehicle-mounted laser profilometer and the BeiDou positioning system,the power spectrum analysis was carried out by the Burg method and the spectrum models of asphalt and cement runways were fitted respectively.Meanwhile,a new exponential lateral coherence function was proposed.Finally,the three-dimensional spatial model was reconstructed by using the transfer function and genetic algorithm.The results show that the error of the measured elevation data is less than 1 cm.The spectral characteristics of different pavement types are significantly different.Among them,the R^(2) of the asphalt runway fitted with the Sussman model is greater than 0.9.The cement runway needs to be characterized by a piecewise function to represent the spectral mutation.The fitting error of the new index's lateral coherence function has been reduced to 0.012.The reconstructed three-dimensional model is in good agreement with the theoretical value and the error does not exceed 0.18 mm^(2) m/c.Finally,a three-dimensional model of 0–20 m in the lateral direction and 3000 m in the longitudinal direction is generated,providing support for aircraft vibration simulation and pavement maintenance. 展开更多
关键词 Runway roughness Power spectral density Lateral coherence function 3D surface reconstruction
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Localization of Oscillation Source in DC Distribution Network Based on Power Spectral Density 被引量:1
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作者 Zida Zhao Ke Peng +1 位作者 Richang Xian Xinhui Zhang 《Journal of Modern Power Systems and Clean Energy》 SCIE EI CSCD 2023年第1期156-167,共12页
Direct current(DC)bus voltage stability is essential for the stable and reliable operation of a DC system.If an oscillation source can be quickly and accurately localized,the oscillation can be adequately eliminated.W... Direct current(DC)bus voltage stability is essential for the stable and reliable operation of a DC system.If an oscillation source can be quickly and accurately localized,the oscillation can be adequately eliminated.We propose a method based on the power spectral density for identifying the voltage oscillation source.Specifically,a DC distribution network model combined with the component connection method is developed,and the network is separated into multiple power modules.Compared with a conventional method,the proposed method does not require determining the model parameters of the entire power grid,which is typically challenging.Furthermore,combined with a novel judgment index,the oscillation source can be identified more intuitively and clearly to enhance the applicability to real power grids.The performance of the proposed method has been evaluated using the MATLAB/Simulink software and PLECS RT Box experimental platform.The simulation and experimental results verify that the proposed method can accurately identify oscillation sources in a DC distribution network. 展开更多
关键词 Direct current(DC)distribution network oscillation source component connection method power spectral density
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The Changes of Heart Rate Power Spectral Density during Head-up Tilt Test
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作者 陈椿 张馥敏 +1 位作者 黄元铸 马文珠 《The Journal of Biomedical Research》 CAS 1998年第1期21-24,共4页
To study the role of autonomic nervous system in the period of developing syncope induced by head-up tilt test(HUT), we analysed the changes of heart rate power spectral density(HRPSD) in 50 patients with unexplained ... To study the role of autonomic nervous system in the period of developing syncope induced by head-up tilt test(HUT), we analysed the changes of heart rate power spectral density(HRPSD) in 50 patients with unexplained syncope, including 15 positive patients (Group 1) and 35 negative patients(Group 2), and 15 negative healthy persons(Group 3) in 5 minute periods before and after tilting and 5 minutes before the end of test. HRPSD and their changes in total(T), very low-frequence(VLF), low-frequence(LF), high-frequence(HF) and the ratio of low/high frequence(LF/HF) were similar (P>0.05) 5 minutes before and after tilting among three groups. Five minutes before the end of test, Group 1 had obvious increase of T, VLF, LF and LF/HF while Group 2 and 3 had not such significant changes. There was significant difference(P<0.01) compared Group 1 with Group 2, 3. The results showed that the abnormal regulatory function of autonomic nervous system played an important role in the mechanism of symcope induced by HUT, the positive group had abnormal increase of sympathetic tone and imbalance of sympathetic/parasympathetic neural tone before syncope appeared. 展开更多
关键词 head-up tilt test SYNCOPE heart rate power spectral density autonomic nervous system
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Cross-spectral recognition method of bridge deck aerodynamic admittance function 被引量:2
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作者 Zhao Lin Ge Yaojun 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2015年第4期595-609,共15页
This study proposes a new identification algorithm about the admittance function, which can estimate the full set of six aerodynamic admittance functions considering cross power spectral density functions about the fo... This study proposes a new identification algorithm about the admittance function, which can estimate the full set of six aerodynamic admittance functions considering cross power spectral density functions about the forces and the turbulence components. The method was first numerically validated through Monte Carlo simulations, and then adopted to estimate the aerodynamic admittance of a streamlined bridge deck. The identification method was further validated through a comparison between the numerical calculation and wind tunnel tests on a moving bridge section. © 2015, Institute of Engineering Mechanics, China Earthquake Administration and Springer-Verlag Berlin Heidelberg. 展开更多
关键词 ALGORITHMS Bridge decks Intelligent systems Monte Carlo methods Numerical methods Power spectral density spectral density Wind stress Wind tunnels
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Research on characterization methods for track irregularities
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作者 Lifeng Xin Lei Xu +3 位作者 Jiaxin Zhang Menglin Pei Jianfeng Mao Dangxiong Wang 《Railway Engineering Science》 2026年第1期25-39,共15页
The characterization of track irregularities is crucial in railway dynamics,as track irregularities are the primary source of internal excitation in railway systems.In this paper,three mathematical models are proposed... The characterization of track irregularities is crucial in railway dynamics,as track irregularities are the primary source of internal excitation in railway systems.In this paper,three mathematical models are proposed to characterize the track irregularities under different circumstances.The first model is a novel explicit track spectrum function,which performs better in reflecting the inherent periodic components of track irregularities than the existing track spectra.On this foundation,the second model,a parameterized track spectrum random model,is proposed to represent the vast measured track irregularities from the probabilistic perspective.Finally,the third model,an imprecise track spectrum interval model based on a neighborhood uniform sampling Bootstrap method,is presented to identify the confidential interval of the track spectra when the track irregularity data are limited.Three examples are illustrated to demonstrate the feasibility of the three track irregularity models in characterizing the track irregularities in different conditions.This research can help capture the railway deformation status and optimize track maintenance strategies. 展开更多
关键词 RAILWAY Track irregularity Power spectral density CHARACTERIZATION Random model Imprecise track spectrum
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Long-Term Bridge Health Evaluation Using Resonant Frequency Changes under Random Loading Conditions
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作者 Thi Kim Chi Duong Bich-Ngoc.Mach +2 位作者 Hoa-Cuc.Nguyen Thi Nhu Quynh Trinh Thanh Q.Nguyen 《Structural Durability & Health Monitoring》 2026年第1期86-120,共35页
This study explores theoretical insights and experimental results on monitoring load-carrying capacity degradation in bridge spans through frequency analysis.Experiments were conducted on real bridge structures,includ... This study explores theoretical insights and experimental results on monitoring load-carrying capacity degradation in bridge spans through frequency analysis.Experiments were conducted on real bridge structures,including the Binh Thuan Bridge,focusing on analyzing the power spectral density(PSD)of vibration signals under random traffic loads.Detailed digital models of various bridge spans with different structural designs and construction periods were developed to ensure diversity.The study utilized PSD to analyze the vibration signals from the bridge spans under various loading conditions,identifying the vibration frequencies and the corresponding response regions.The research correlated the observed frequency changes of PSD with the actual deterioration of the bridges over time,identifying patterns that indicate a reduction in stiffness.Experiments demonstrated that frequency changes,particularly in high-frequency regions,are directly related to a reduction in the stiffness of bridge spans.This supports the hypothesis that natural frequencies can serve as effective indicators of structural damage.Furthermore,the emergence and shift of resonant frequency regions provide valuable insights into the extent of damage in actual bridge spans,highlighting the potential for using changes in resonant frequency regions as a new tool for structural damage detection. 展开更多
关键词 FREQUENCY power spectral density vibration signals vibration frequencies resonant frequency regions structural damage detection
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Influence of hydration on the thermal transport properties of yttria-doped barium zirconate
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作者 Jianqun Gao Zhaoyang Wang +1 位作者 Yuhang Jing Yufei Gao 《Chinese Physics B》 2026年第2期510-518,共9页
Perovskites exhibit excellent protonic conductivity in the mid-temperature range,and among them,yttria-doped barium zirconate(BZY)is considered one of the most promising perovskite proton conductors.Molecular simulati... Perovskites exhibit excellent protonic conductivity in the mid-temperature range,and among them,yttria-doped barium zirconate(BZY)is considered one of the most promising perovskite proton conductors.Molecular simulations provide an efficient approach to investigating the thermal transport behavior of nanocrystalline materials.The effect of doping concentration on the thermal transport properties of BZY structures was investigated using the equilibrium molecular dynamics(EMD)method combined with phonon spectral energy density(SED)analysis.The results show that the thermal transport properties gradually decrease with increasing doping concentration,and for structures with dopants only and without oxygen vacancies,the thermal conductivity exhibits a similar decreasing trend but remains higher than that of structures containing both dopants and oxygen vacancies.Comparison of phonon lifetime and group velocity reveals that oxygen vacancy defects enhance phonon scattering,thereby leading to a reduction in thermal transport properties,while doping reduces the thermal transport properties by weakening lattice harmonicity.The effect of different hydration levels on the thermal transport properties of BZY was also investigated,and the results indicate that the thermal conductivity fluctuates in structures with low hydration levels and continues to decrease as the proton defect concentration increases with hydration.Further analysis of phonon lifetime and group velocity demonstrates that proton defects reduce the thermal transport properties through both enhanced phonon diffusion and weakened harmonicity. 展开更多
关键词 molecular dynamics spectral energy density HYDRATION thermal transport property
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Porosity Evaluation and the Power Spectral Densities Analyses of Carbon-Nickel Composite Films Annealed at Different Temperatures
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作者 V.Dalouji S.M.Elahi +1 位作者 A.Ghaderi S.Solaymani 《Chinese Physics Letters》 SCIE CAS CSCD 2016年第8期96-99,共4页
The densification and the fractal dimensions of carbon-nickel films annealed at different temperatures 300, 500, 800, and 1000℃ with emphasis on porosity evaluation are investigated. For this purpose, the refractive... The densification and the fractal dimensions of carbon-nickel films annealed at different temperatures 300, 500, 800, and 1000℃ with emphasis on porosity evaluation are investigated. For this purpose, the refractive index of films is determined from transmittance spectra. Three different regimes are identified, T 〈 500℃, 500℃ 〈 T 〈 800℃ and T 〉 800℃. The Rutherford baekscattering spectra show that with increasing the annealing temperature, the concentration of nickel atoms into films decreases. It is shown that the effect of annealing temperatures for increasing films densification at T 〈 500℃ and T 〉 800℃ is greater than the effect of nickel concentrations. It is observed that the effect of decreasing nickel atoms into films at 500℃ 〈 T 〈 800℃ strongly causes improving porosity and decreasing densification. The fractal dimensions of carbon-nickel films annealed from 300 to 500℃ are increased, while from 500 to 1000℃ these characteristics are decreased. It can be seen that at 800℃, films have maximum values of porosity and roughness. 展开更多
关键词 of on it Ni Porosity Evaluation and the Power spectral Densities Analyses of Carbon-Nickel Composite Films Annealed at Different Temperatures is that into
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Non-Markovian dynamics of two non-coupled qubits interacting with two separate reservoirs with different spectral densities
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作者 王小云 丁邦福 赵鹤平 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第4期128-132,共5页
The dynamics of two non-coupled qubits independently interacting with their reservoirs is solved by the time convolutionless projection operator method. We study two-qubit quantum correlation dynamics for two differen... The dynamics of two non-coupled qubits independently interacting with their reservoirs is solved by the time convolutionless projection operator method. We study two-qubit quantum correlation dynamics for two different types of spectral densities, which are a Lorentzian distribution and an Ohmic spectral density with a Lorentzian–Drude cutoff function. For two qubits initially prepared in the initial Bell state, quantum discord can keep longer time and reach larger values in nonMarkovian reservoirs for the first spectral distribution or by reducing the cutoff frequency for the second case. For the initial Bell-like state, the dynamic behaviors of quantum discord and entanglement are compared. The results show that a long time of quantum correlation can be obtained by adjusting some parameters in experiment and further confirm that the discord can capture quantum correlation in addition to entanglement. 展开更多
关键词 Lorentzian and Ohmic spectral densities the time convolution-less projection operator method non-Markovian and Markovian regime quantum discord and entanglement
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rTMS Improves Cognitive Function and Brain Network Connectivity in Patients With Alzheimer’s Disease
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作者 XU Gui-Zhi LIU Lin +4 位作者 GUO Miao-Miao WANG Tian GAO Jiao-Jiao JI Yong WANG Pan 《生物化学与生物物理进展》 北大核心 2025年第8期2131-2145,共15页
Objective Repetitive transcranial magnetic stimulation(rTMS)has demonstrated efficacy in enhancing neurocognitive performance in Alzheimer’s disease(AD),but the neurobiological mechanisms linking synaptic pathology,n... Objective Repetitive transcranial magnetic stimulation(rTMS)has demonstrated efficacy in enhancing neurocognitive performance in Alzheimer’s disease(AD),but the neurobiological mechanisms linking synaptic pathology,neural oscillatory dynamics,and brain network reorganization remain unclear.This investigation seeks to systematically evaluate the therapeutic potential of rTMS as a non-invasive neuromodulatory intervention through a multimodal framework integrating clinical assessments,molecular profiling,and neurophysiological monitoring.Methods In this prospective double-blind trial,12 AD patients underwent a 14-day protocol of 20 Hz rTMS,with comprehensive multimodal assessments performed pre-and postintervention.Cognitive functioning was quantified using the mini-mental state examination(MMSE)and Montreal cognitive assessment(MOCA),while daily living capacities and neuropsychiatric profiles were respectively evaluated through the activities of daily living(ADL)scale and combined neuropsychiatric inventory(NPI)-Hamilton depression rating scale(HAMD).Peripheral blood biomarkers,specifically Aβ1-40 and phosphorylated tau(p-tau181),were analyzed to investigate the effects of rTMS on molecular metabolism.Spectral power analysis was employed to investigate rTMS-induced modulations of neural rhythms in AD patients,while brain network analyses incorporating topological properties were conducted to examine stimulus-driven network reorganization.Furthermore,systematic assessment of correlations between cognitive scale scores,blood biomarkers,and network characteristics was performed to elucidate cross-modal therapeutic associations.Results Clinically,MMSE and MOCA scores improved significantly(P<0.05).Biomarker showed that Aβ1-40 level increased(P<0.05),contrasting with p-tau181 reduction.Moreover,the levels of Aβ1-40 were positively correlated with MMSE and MOCA scores.Post-intervention analyses revealed significant modulations in oscillatory power,characterized by pronounced reductions in delta(P<0.05)and theta bands(P<0.05),while concurrent enhancements were observed in alpha,beta,and gamma band activities(all P<0.05).Network analysis revealed frequency-specific reorganization:clustering coefficients were significantly decreased in delta,theta,and alpha bands(P<0.05),while global efficiency improvement was exclusively detected in the delta band(P<0.05).The alpha band demonstrated concurrent increases in average nodal degree(P<0.05)and characteristic path length reduction(P<0.05).Further research findings indicate that the changes in the clinical scale HAMD scores before and after rTMS stimulation are negatively correlated with the changes in the blood biomarkers Aβ1-40 and p-tau181.Additionally,the changes in the clinical scales MMSE and MoCA scores were negatively correlated with the changes in the node degree of the alpha frequency band and negatively correlated with the clustering coefficient of the delta frequency band.However,the changes in MMSE scores are positively correlated with the changes in global efficiency of both the delta and alpha frequency bands.Conclusion 20 Hz rTMS targeting dorsolateral prefrontal cortex(DLPFC)significantly improves cognitive function and enhances the metabolic clearance ofβ-amyloid and tau proteins in AD patients.This neurotherapeutic effect is mechanistically associated with rTMS-mediated frequency-selective neuromodulation,which enhances the connectivity of oscillatory networks through improved neuronal synchronization and optimized topological organization of functional brain networks.These findings not only support the efficacy of rTMS as an adjunctive therapy for AD but also underscore the importance of employing multiple assessment methods—including clinical scales,blood biomarkers,and EEG——in understanding and monitoring the progression of AD.This research provides a significant theoretical foundation and empirical evidence for further exploration of rTMS applications in AD treatment. 展开更多
关键词 transcranial magnetic stimulation Alzheimer’s disease power spectral density ELECTROENCEPHALOGRAM brain functional network
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Comparing different segments in shut-in pressure signals:New insights into frequency range and energy distribution
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作者 Ya-Jing Wang Xiao-Dong Hu +5 位作者 Fu-Jian Zhou Pu-Kang Yi Wei-Peng Guan Yang Qiu En-Jia Dong Peng-Tian Zhang 《Petroleum Science》 2025年第1期442-456,共15页
Water hammer diagnostics is an important fracturing diagnosis technique to evaluate fracture locations and other downhole events in fracturing. The evaluation results are obtained by analyzing shut-in water hammer pre... Water hammer diagnostics is an important fracturing diagnosis technique to evaluate fracture locations and other downhole events in fracturing. The evaluation results are obtained by analyzing shut-in water hammer pressure signal. The field-sampled water hammer signal is often disturbed by noise interference. Noise interference exists in various pumping stages during water hammer diagnostics, with significantly different frequency range and energy distribution. Clarifying the differences in frequency range and energy distribution between effective water hammer signals and noise is the basis of setting specific filtering parameters, including filtering frequency range and energy thresholds. Filtering specifically could separate the effective signal and noise, which is the key to ensuring the accuracy of water hammer diagnosis. As an emerging technique, there is a lack of research on the frequency range and energy distribution of effective signals in water hammer diagnostics. In this paper, the frequency range and energy distribution characteristics of field-sampled water hammer signals were clarified quantitatively and qualitatively for the first time by a newly proposed comprehensive water hammer segmentation-energy analysis method. The water hammer signals were preprocessed and divided into three segments, including pre-shut-in, water hammer oscillation, and leak-off segment. Then, the three segments were analyzed by energy analysis and correlation analysis. The results indicated that, one aspect, the frequency range of water hammer oscillation spans from 0 to 0.65 Hz, considered as effective water hammer signal. The pre-shut-in and leak-off segment ranges from 0 to 0.35 Hz and 0-0.2 Hz respectively. Meanwhile, odd harmonics were manifested in water hammer oscillation segment, with the harmonic frequencies ranging approximately from 0.07 to 0.75 Hz. Whereas integer harmonics were observed in pre-shut-in segment, ranging from 6 to 40 Hz. The other aspect, the energy distribution of water hammer signals was analyzed in different frequency ranges. In 0-1 Hz, an exponential decay was observed in all three segments. In 1-100 Hz, a periodical energy distribution was observed in pre-shut-in segment, an exponential decay was observed in water hammer oscillation, and an even energy distribution was observed in leak-off segment. In 100-500 Hz, an even energy distribution was observed in those three segments, yet the highest magnitude was noted in leak-off segment. In this study, the effective frequency range and energy distribution characteristics of the field-sampled water hammer signals in different segments were sufficiently elucidated quantitatively and qualitatively for the first time, laying the groundwork for optimizing the filtering parameters of the field filtering models and advancing the accuracy of identifying downhole event locations. 展开更多
关键词 Hydraulic fracturing Fracture diagnostics Water hammer Energy spectral density analysis Segmentation analysis of pressure signals Frequency range Energy distribution
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