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全自动微生物流水线改善病原体感染诊断效能的价值评估
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作者 金静 隋文君 田晓波 《标记免疫分析与临床》 2025年第11期2361-2366,共6页
目的从成本及质量两维度评估全自动微生物流水线(walk away specimen processor,WASP)改善病原体感染的诊断效能。方法回顾性队列研究,纳入2023年1月至12月传统手工操作的痰、支气管肺泡灌洗液(bronchoalveolar lavage fluid,BALF)、尿... 目的从成本及质量两维度评估全自动微生物流水线(walk away specimen processor,WASP)改善病原体感染的诊断效能。方法回顾性队列研究,纳入2023年1月至12月传统手工操作的痰、支气管肺泡灌洗液(bronchoalveolar lavage fluid,BALF)、尿液样本(对照组,n=12653例)和2024年1月至12月WASP操作的痰、BALF、尿液样本(实验组,n=4228例),常规8h工作制下,对比两组方法间在成本(人员成本、时间成本、耗材成本和设备成本)及质量控制(污染、错误、丢失)的差异,采用SPSS 27.0.1软件进行统计学分析。结果实验组与对照组比较,人员成本(人员数/1000标本)减少34.4%[(42.0±2.0人)vs(64.0±3.0人),P<0.001],标本接种耗时与标本数量有关,标本数量≤25例时,两组间耗时无差异,标本数量≥26例,实验组耗时显著缩短(P=0.001),且随标本数量增加耗时差增大,常规工作制下实验室周转时间(turnaround time,TAT)差异无统计学意义(P=0.778),耗材损耗率减少23.5%[(1.3±0.5)%vs(1.7±0.4)%,P=0.042],设备成本、维护费用及折旧费用显著高于对照组(P<0.05);质量控制方面,携带污染率降低4.0%(0.5%vs 4.5%,P=0.025);环境污染率降低5.6%(1.7%vs 7.3%,P<0.001);标本编号错误率降低1.4%(0.0%vs 1.4%,P<0.001);接种平皿错误率(含漏种)降低2.1%(0.0%vs 2.1%,P<0.001);培养箱选择错误率降低2.5%(0.3%vs 2.8%,P<0.001);报告错误率降低0.4%(0.2%vs 0.6%,P=0.001);平皿丢失率两组间差异无统计学意义(P=0.077)。结论WASP可显著优化成本,降低污染,提高准确性,可通过优化排班制度缩短TAT。 展开更多
关键词 微生物流水线 成本 质量控制 污染 周转时间
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How Liquid Based Microbiology Can Change the Workflow in the Microbiology Laboratories
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作者 Carla Fontana Marco Favaro Cartesio Favalli 《Advances in Microbiology》 2013年第6期504-510,共7页
Liquid-based microbiology (LBM) is the future for the technological development of microbiology laboratories. In particular, the Eswab system (by Copan) simplifies and streamlines specimen collection and represents th... Liquid-based microbiology (LBM) is the future for the technological development of microbiology laboratories. In particular, the Eswab system (by Copan) simplifies and streamlines specimen collection and represents the only liquid system supporting the recovery of all types of bacteria (aerobic, anaerobic, and fastidious bacteria). In addition, LBM offers advantages in the efficiency of microorganism recovery and ease of sampling, transport, and storage. LBM also allows the introduction of true automation in the laboratory: either by using Copan ? (Walk-Away Specimen Processor) or any other commercially available specimen processor that utilizes LBM. In this paper, we illustrate how LBM can positively change laboratory workflow by illustrating several years of our experience with LBM. LBM allows clinical specimen optimization and has several important advantages: cost reduction (due to the smaller number of different devices used), time savings for medical or nursing staff (less confusion in collection device selection and fewer samples being collected), time savings for laboratory staff (fewer samples to access and handle for individual investigations), and patient comfort improvement (multiple sample collection can be avoided). A unique collection device for several investigations also guarantees quality due to the uniformity of the sample and standardization of procedures. 展开更多
关键词 WORKFLOW Liquid-Based MICROBIOLOGY specimen processor Molecular Assays Rational Use of Laboratory Resources
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