Through the field survey of traditional rural settlement,it has found that the typical spatial construction model shows the duality of matrix and landmark and they are in a relation of reciprocal causality.However,und...Through the field survey of traditional rural settlement,it has found that the typical spatial construction model shows the duality of matrix and landmark and they are in a relation of reciprocal causality.However,under the impact of urbanization and modernization,this spatial construction model is disappearing,and those natural villages are integrated and reconstructed at a high speed and in a large scale during the construction of new rural communities,leading to a lack of geographical construction system and a damage of ecological living environment.In the perspective of prototype theory,the duality feature should be combined with spatial construction model to guide the inheritance and application of spatial construction model of traditional rural settlements and seek for new spatial development approach for new rural communities based on the sustainable,alternative and transformation strategies.展开更多
The emergence of spatial genomics has introduced new possi-bilities for studying structure–function relationships in neuropsy-chiatric disorders.Spatial transcriptomics allows the detection of thousands of genes simu...The emergence of spatial genomics has introduced new possi-bilities for studying structure–function relationships in neuropsy-chiatric disorders.Spatial transcriptomics allows the detection of thousands of genes simultaneously up to single-cell resolu-tion,providing the spatial location of gene transcriptional activ-ity within a tissue sample.Spatial genomics technologies are de-veloping rapidly,and many of them have been used to construct brain spatial genomics atlases.A brain spatial transcriptomic at-las is a map of the gene expression across brain regions in situ—i.e.,within their anatomical context—often at single-cell or near-single-cell resolution.The brain spatial genomics atlas has been constructed for a few species including mice and humans.展开更多
文摘Through the field survey of traditional rural settlement,it has found that the typical spatial construction model shows the duality of matrix and landmark and they are in a relation of reciprocal causality.However,under the impact of urbanization and modernization,this spatial construction model is disappearing,and those natural villages are integrated and reconstructed at a high speed and in a large scale during the construction of new rural communities,leading to a lack of geographical construction system and a damage of ecological living environment.In the perspective of prototype theory,the duality feature should be combined with spatial construction model to guide the inheritance and application of spatial construction model of traditional rural settlements and seek for new spatial development approach for new rural communities based on the sustainable,alternative and transformation strategies.
文摘The emergence of spatial genomics has introduced new possi-bilities for studying structure–function relationships in neuropsy-chiatric disorders.Spatial transcriptomics allows the detection of thousands of genes simultaneously up to single-cell resolu-tion,providing the spatial location of gene transcriptional activ-ity within a tissue sample.Spatial genomics technologies are de-veloping rapidly,and many of them have been used to construct brain spatial genomics atlases.A brain spatial transcriptomic at-las is a map of the gene expression across brain regions in situ—i.e.,within their anatomical context—often at single-cell or near-single-cell resolution.The brain spatial genomics atlas has been constructed for a few species including mice and humans.