This paper proposes a new step-by-step Chebyshev space-time spectral method to analyze the force vibration of functionally graded material structures.Although traditional space-time spectral methods can reduce the acc...This paper proposes a new step-by-step Chebyshev space-time spectral method to analyze the force vibration of functionally graded material structures.Although traditional space-time spectral methods can reduce the accuracy mismatch between tem-poral low-order finite difference and spatial high-order discre tization,the ir time collocation points must increase dramatically to solve highly oscillatory solutions of structural vibration,which results in a surge in computing time and a decrease in accuracy.To address this problem,we introduced the step-by-step idea in the space-time spectral method.The Chebyshev polynomials and Lagrange's equation were applied to derive discrete spatial goverming equations,and a matrix projection method was used to map the calculation results of prev ious steps as the initial conditions of the subsequent steps.A series of numerical experiments were carried out.The results of the proposed method were compared with those obtained by traditional space-time spectral methods,which showed that higher accuracy could be achieved in a shorter computation time than the latter in highly oscillatory cases.展开更多
Existing orthogonal space-time block coding(OSTBC)schemes for backscatter communication systems cannot achieve a full transmission code rate when the tag is equipped with more than two antennas.In this paper,we propos...Existing orthogonal space-time block coding(OSTBC)schemes for backscatter communication systems cannot achieve a full transmission code rate when the tag is equipped with more than two antennas.In this paper,we propose a quasi-orthogonal spacetime block code(QOSTBC)that can achieve a full transmission code rate for backscatter communication systems with a four-antenna tag and then extend the scheme to support tags with 2i antennas.Specifically,we first present the system model for the backscatter system.Next,we propose the QOSTBC scheme to encode the tag signals.Then,we provide the corresponding maximum likelihood detection algorithms to recover the tag signals.Finally,simulation results are provided to demonstrate that our proposed QOSTBC scheme and the detection algorithm can achieve a better transmission code rate or symbol error rate performance for backscatter communication systems compared with benchmark schemes.展开更多
In this paper,we propose a hybrid decode-and-forward and soft information relaying(HDFSIR)strategy to mitigate error propagation in coded cooperative communications.In the HDFSIR approach,the relay operates in decode-...In this paper,we propose a hybrid decode-and-forward and soft information relaying(HDFSIR)strategy to mitigate error propagation in coded cooperative communications.In the HDFSIR approach,the relay operates in decode-and-forward(DF)mode when it successfully decodes the received message;otherwise,it switches to soft information relaying(SIR)mode.The benefits of the DF and SIR forwarding strategies are combined to achieve better performance than deploying the DF or SIR strategy alone.Closed-form expressions for the outage probability and symbol error rate(SER)are derived for coded cooperative communication with HDFSIR and energy-harvesting relays.Additionally,we introduce a novel normalized log-likelihood-ratio based soft estimation symbol(NL-SES)mapping technique,which enhances soft symbol accuracy for higher-order modulation,and propose a model characterizing the relationship between the estimated complex soft symbol and the actual high-order modulated symbol.Further-more,the hybrid DF-SIR strategy is extended to a distributed Alamouti space-time-coded cooperative network.To evaluate the~performance of the proposed HDFSIR strategy,we implement extensive Monte Carlo simulations under varying channel conditions.Results demonstrate significant improvements with the hybrid technique outperforming individual DF and SIR strategies in both conventional and distributed Alamouti space-time coded cooperative networks.Moreover,at a SER of 10^(-3),the proposed NL-SES mapping demonstrated a 3.5 dB performance gain over the conventional averaging one,highlighting its superior accuracy in estimating soft symbols for quadrature phase-shift keying modulation.展开更多
In this article,several kinds of novel exact waves solutions of three well-known different space-time fractional nonlinear coupled waves dynamical models are constructed with the aid of simpler and effective improved ...In this article,several kinds of novel exact waves solutions of three well-known different space-time fractional nonlinear coupled waves dynamical models are constructed with the aid of simpler and effective improved auxiliary equation method.Firstly we will investigate space-time fractional coupled Boussinesq-Burger dynamical model,which is used to model the propagation of water waves in shallow sea and harbor,and has many applications in ocean engineering.Secondly,we will investigate the space-time fractional coupled Drinfeld-SokolovWilson equation which is used to characterize the nonlinear surface gravity waves propagation over horizontal seabed.Thirdly,we will investigate the space-time-space fractional coupled Whitham-Broer-Kaup equation which is used to model the shallow water waves in a porous medium near a dam.We obtained different solutions in terms of trigonometric,hyperbolic,exponential and Jacobi elliptic functions.Furthermore,graphics are plotted to explain the different novel structures of obtained solutions such as multi solitons interaction,periodic soliton,bright and dark solitons,Kink and anti-Kink solitons,breather-type waves and so on,which have applications in ocean engineering,fluid mechanics and other related fields.We hope that our results obtained in this article will be useful to understand many novel physical phenomena in applied sciences and other related fields.展开更多
This study introduces a novel single-layer meshless method,the space-time collocation method based on multiquadric-radial basis functions(MQ-RBF),for solving the Benjamin-Bona-Mahony-Burgers(BBMB)equation.By reconstru...This study introduces a novel single-layer meshless method,the space-time collocation method based on multiquadric-radial basis functions(MQ-RBF),for solving the Benjamin-Bona-Mahony-Burgers(BBMB)equation.By reconstructing the time variable as a space variable,this method establishes a combined space-time structure that can eliminate the two-step computational process required in traditional grid methods.By introducing shape parameteroptimized MQ-RBF,high-precision discretization of the nonlinear,dispersive,and dissipative terms in the BBMB equation is achieved.The numerical experiment section validates the effectiveness of the proposed method through three benchmark examples.This method shows significant advantages in computational efficiency,providing a new numerical tool for engineering applications in fields such as shallow water wave dynamics.展开更多
The generalized Thirring model with impurity coupling is defined on two-dimensional noncommutativespace-time,a modified propagator and free energy are derived by means of functional integrals method.Moreover,quantum f...The generalized Thirring model with impurity coupling is defined on two-dimensional noncommutativespace-time,a modified propagator and free energy are derived by means of functional integrals method.Moreover,quantum fluctuations and excitation energies are calculated on two-dimensional black hole and soliton background.展开更多
The emerging virtual coupling technology aims to operate multiple train units in a Virtually Coupled Train Set(VCTS)at a minimal but safe distance.To guarantee collision avoidance,the safety distance should be calcula...The emerging virtual coupling technology aims to operate multiple train units in a Virtually Coupled Train Set(VCTS)at a minimal but safe distance.To guarantee collision avoidance,the safety distance should be calculated using the state-of-the-art space-time separation principle that separates the Emergency Braking(EB)trajectories of two successive units during the whole EB process.In this case,the minimal safety distance is usually numerically calculated without an analytic formulation.Thus,the constrained VCTS control problem is hard to address with space-time separation,which is still a gap in the existing literature.To solve this problem,we propose a Distributed Economic Model Predictive Control(DEMPC)approach with computation efficiency and theoretical guarantee.Specifically,to alleviate the computation burden,we transform implicit safety constraints into explicitly linear ones,such that the optimal control problem in DEMPC is a quadratic programming problem that can be solved efficiently.For theoretical analysis,sufficient conditions are derived to guarantee the recursive feasibility and stability of DEMPC,employing compatibility constraints,tube techniques and terminal ingredient tuning.Moreover,we extend our approach with globally optimal and distributed online EB configuration methods to shorten the minimal distance among VCTS.Finally,experimental results demonstrate the performance and advantages of the proposed approaches.展开更多
In our investigation,we explore the quantum dynamics of charge-free scalar particles through the Klein–Gordon equation within the framework of rainbow gravity,considering the Bonnor–Melvin-Lambda(BML)space-time back...In our investigation,we explore the quantum dynamics of charge-free scalar particles through the Klein–Gordon equation within the framework of rainbow gravity,considering the Bonnor–Melvin-Lambda(BML)space-time background.The BML solution is characterized by the magnetic field strength along the axis of the symmetry direction which is related to the cosmological constantΛand the topological parameterαof the geometry.The behavior of charge-free scalar particles described by the Klein–Gordon equation is investigated,utilizing two sets of rainbow functions:(i)f(χ)=■,h(χ)=1 and(ii)f(χ)=1,h(χ)=1+βХ/2.Here 0<(Х=■)≤1 with E representing the particle's energy,Ep is the Planck's energy,andβis the rainbow parameter.We obtain the approximate analytical solutions for the scalar particles and conduct a thorough analysis of the obtained results.Afterwards,we study the quantum dynamics of quantum oscillator fields within this BML space-time,employing the Klein–Gordon oscillator.Here also,we choose the same sets of rainbow functions and obtain the approximate eigenvalue solution for the oscillator fields.Notably,we demonstrate that the relativistic approximate energy profiles of charge-free scalar particles and oscillator fields get influenced by the topology of the geometry and the cosmological constant.Furthermore,we show that the energy profiles of scalar particles receive modifications from the rainbow parameter and the quantum oscillator fields by both the rainbow parameter and the frequency of oscillation.展开更多
In this paper,we mainly discuss a discrete estimation of the average differential entropy for a continuous time-stationary ergodic space-time random field.By estimating the probability value of a time-stationary rando...In this paper,we mainly discuss a discrete estimation of the average differential entropy for a continuous time-stationary ergodic space-time random field.By estimating the probability value of a time-stationary random field in a small range,we give an entropy estimation and obtain the average entropy estimation formula in a certain bounded space region.It can be proven that the estimation of the average differential entropy converges to the theoretical value with a probability of 1.In addition,we also conducted numerical experiments for different parameters to verify the convergence result obtained in the theoretical proofs.展开更多
Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration...Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal cord.Here we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord injury.We report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal directions.Such Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder functions.Importantly,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord injury.These findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.展开更多
Underwater monopulse space-time adaptive track-before-detect method,which combines space-time adaptive detector(STAD)and the track-before-detect algorithm based on dynamic programming(DP-TBD),denoted as STAD-DP-TBD,ca...Underwater monopulse space-time adaptive track-before-detect method,which combines space-time adaptive detector(STAD)and the track-before-detect algorithm based on dynamic programming(DP-TBD),denoted as STAD-DP-TBD,can effectively detect low-speed weak targets.However,due to the complexity and variability of the underwater environment,it is difficult to obtain sufficient secondary data,resulting in a serious decline in the detection and tracking performance,and leading to poor robustness of the algorithm.In this paper,based on the adaptive matched filter(AMF)test and the RAO test,underwater monopulse AMF-DP-TBD algorithm and RAO-DP-TBD algorithm which incorporate persymmetry and symmetric spectrum,denoted as PSAMF-DP-TBD and PS-RAO-DP-TBD,are proposed and compared with the AMF-DP-TBD algorithm and RAO-DP-TBD algorithm based on persymmetry array,denoted as P-AMF-DP-TBD and P-RAO-DP-TBD.The simulation results show that the four methods can work normally with sufficient secondary data and slightly insufficient secondary data,but when the secondary data is severely insufficient,the P-AMF-DP-TBD and P-RAO-DP-TBD algorithms has failed while the PSAMF-DP-TBD and PS-RAO-DP-TBD algorithms still have good detection and tracking capabilities.展开更多
Traumatic brain injury involves complex pathophysiological mechanisms,among which oxidative stress significantly contributes to the occurrence of secondary injury.In this study,we evaluated hypidone hydrochloride(YL-0...Traumatic brain injury involves complex pathophysiological mechanisms,among which oxidative stress significantly contributes to the occurrence of secondary injury.In this study,we evaluated hypidone hydrochloride(YL-0919),a self-developed antidepressant with selective sigma-1 receptor agonist properties,and its associated mechanisms and targets in traumatic brain injury.Behavioral experiments to assess functional deficits were followed by assessment of neuronal damage through histological analyses and examination of blood-brain barrier permeability and brain edema.Next,we investigated the antioxidative effects of YL-0919 by assessing the levels of traditional markers of oxidative stress in vivo in mice and in vitro in HT22 cells.Finally,the targeted action of YL-0919 was verified by employing a sigma-1 receptor antagonist(BD-1047).Our findings demonstrated that YL-0919 markedly improved deficits in motor function and spatial cognition on day 3 post traumatic brain injury,while also decreasing neuronal mortality and reversing blood-brain barrier disruption and brain edema.Furthermore,YL-0919 effectively combated oxidative stress both in vivo and in vitro.The protective effects of YL-0919 were partially inhibited by BD-1047.These results indicated that YL-0919 relieved impairments in motor and spatial cognition by restraining oxidative stress,a neuroprotective effect that was partially reversed by the sigma-1 receptor antagonist BD-1047.YL-0919 may have potential as a new treatment for traumatic brain injury.展开更多
BACKGROUND At present,the influencing factors of social function in patients with residual depressive symptoms are still unclear.Residual depressive symptoms are highly harmful,leading to low mood in patients,affectin...BACKGROUND At present,the influencing factors of social function in patients with residual depressive symptoms are still unclear.Residual depressive symptoms are highly harmful,leading to low mood in patients,affecting work and interpersonal communication,increasing the risk of recurrence,and adding to the burden on families.Studying the influencing factors of their social function is of great significance.AIM To explore the social function score and its influencing factors in patients with residual depressive symptoms.METHODS This observational study surveyed patients with residual depressive symptoms(case group)and healthy patients undergoing physical examinations(control group).Participants were admitted between January 2022 and December 2023.Social functioning was assessed using the Sheehan Disability Scale(SDS),and scores were compared between groups.Factors influencing SDS scores in patients with residual depressive symptoms were analyzed by applying multiple linear regression while using the receiver operating characteristic curve,and these RESULTS The SDS scores of the 158 patients with depressive symptoms were 11.48±3.26.Compared with the control group,the SDS scores and all items in the case group were higher.SDS scores were higher in patients with relapse,discon-tinuous medication,drug therapy alone,severe somatic symptoms,obvious residual symptoms,and anxiety scores≥8.Disease history,medication compliance,therapy method,and residual symptoms correlated positively with SDS scores(r=0.354,0.414,0.602,and 0.456,respectively).Independent influencing factors included disease history,medication compliance,therapy method,somatic symptoms,residual symptoms,and anxiety scores(P<0.05).The areas under the curve for predicting social functional impairment using these factors were 0.713,0.559,0.684,0.729,0.668,and 0.628,respectively,with sensitivities of 79.2%,61.8%,76.8%,81.7%,63.6%,and 65.5%and specificities of 83.3%,87.5%,82.6%,83.3%,86.7%,and 92.1%,respectively.CONCLUSION The social function scores of patients with residual symptoms of depression are high.They are affected by disease history,medication compliance,therapy method,degree of somatic symptoms,residual symptoms,and anxiety.展开更多
Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery ...Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes following thoracic contusive spinal cord injury. After a 7-day recovery period after spinal cord injury, mice were assigned to either a trained group(10 weeks of voluntary running wheel or forced treadmill exercise) or an untrained group. Bi-weekly assessments revealed that the exercise-trained group, particularly the voluntary wheel exercise subgroup, displayed significantly improved locomotor recovery, more plasticity of dopaminergic and serotonin modulation compared with the untrained group. Additionally, exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury areas across groups, exercise training promoted terminal innervation of descending axons. In summary, voluntary wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury, emphasizing the role of exercise modality in promoting recovery and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.展开更多
This paper presents a physically plausible and somewhat illuminating first step in extending the fundamental principles of mechanical stress and strain to space-time. Here the geometry of space-time, encoded in the me...This paper presents a physically plausible and somewhat illuminating first step in extending the fundamental principles of mechanical stress and strain to space-time. Here the geometry of space-time, encoded in the metric tensor, is considered to be made up of a dynamic lattice of extremely small, localized fields that form a perfectly elastic Lorentz symmetric space-time at the global (macroscopic) scale. This theoretical model of space-time at the Planck scale leads to a somewhat surprising result in which matter waves in curved space-time radiate thermal gravitational energy, as well as an equally intriguing relationship for the anomalous dispersion of light in a gravitational field.展开更多
Space-time coding radar has been recently proposed and investigated.It is a radar framework which can perform transmit beamforming at the receiver.However,the range resolution decreases when the number of the transmit...Space-time coding radar has been recently proposed and investigated.It is a radar framework which can perform transmit beamforming at the receiver.However,the range resolution decreases when the number of the transmit element increases.A subarray-based space-time coding(sub-STC)radar is explored to alleviate the range resolution reduction.For the proposed radar configuration,an identical waveform is transmitted and it introduces a small time offset in different subarrays.The multidimensional ambiguity function of sub-STC radar is defined by considering resolutions in multiple domains including the range,Doppler,angle and probing direction.Analyses on properties of the multi-dimensional ambiguity function of the sub-STC radar with regard to the spatial coverage,resolution performance and low sidelobes are also given.Results reveal that the range resolution and low sidelobes performance are improved with the proposed approach.展开更多
Protonic solid oxide electrolysis cells(P-SOECs)are a promising technology for water electrolysis to produce green hydrogen.However,there are still challenges related key materials and anode/electrolyte interface.P-SO...Protonic solid oxide electrolysis cells(P-SOECs)are a promising technology for water electrolysis to produce green hydrogen.However,there are still challenges related key materials and anode/electrolyte interface.P-SOECs with Zr-rich electrolyte,called Zr-rich side P-SOECs,possess high thermodynamically stability under high steam concentrations but the large reaction resistances and the current leakage,thus the inferior performances.In this study,an efficient functional interlayer Ba_(0.95)La_(0.05)Fe_(0.8)Zn_(0.2)O_(3-δ)(BLFZ)in-between the anode and the electrolyte is developed.The electrochemical performances of P-SOECs are greatly enhanced because the BLFZ can greatly increase the interface contact,boost anode reaction kinetics,and increase proton injection into electrolyte.As a result,the P-SOEC yields high current density of 0.83 A cm^(-2) at 600℃ in 1.3 Vamong all the reported Zr-rich side cells.This work not only offers an efficient functional interlayer for P-SOECs but also holds the potential to achieve P-SOECs with high performances and long-term stability.展开更多
The M1/M2 phenotypic shift of microglia after spinal cord injury plays an important role in the regulation of neuroinflammation during the secondary injury phase of spinal cord injury.Regulation of shifting microglia ...The M1/M2 phenotypic shift of microglia after spinal cord injury plays an important role in the regulation of neuroinflammation during the secondary injury phase of spinal cord injury.Regulation of shifting microglia polarization from M1(neurotoxic and proinflammatory type)to M2(neuroprotective and anti-inflammatory type)after spinal cord injury appears to be crucial.Tryptanthrin possesses an anti-inflammatory biological function.However,its roles and the underlying molecular mechanisms in spinal cord injury remain unknown.In this study,we found that tryptanthrin inhibited microglia-derived inflammation by promoting polarization to the M2 phenotype in vitro.Tryptanthrin promoted M2 polarization through inactivating the cGAS/STING/NF-κB pathway.Additionally,we found that targeting the cGAS/STING/NF-κB pathway with tryptanthrin shifted microglia from the M1 to M2 phenotype after spinal cord injury,inhibited neuronal loss,and promoted tissue repair and functional recovery in a mouse model of spinal cord injury.Finally,using a conditional co-culture system,we found that microglia treated with tryptanthrin suppressed endoplasmic reticulum stress-related neuronal apoptosis.Taken together,these results suggest that by targeting the cGAS/STING/NF-κB axis,tryptanthrin attenuates microglia-derived neuroinflammation and promotes functional recovery after spinal cord injury through shifting microglia polarization to the M2 phenotype.展开更多
In this paper,a simple direct space-time semi-analytical meshless scheme is proposed for the numerical approximation of the coupled Burgers'equations.During the whole solution procedure,two different schemes are c...In this paper,a simple direct space-time semi-analytical meshless scheme is proposed for the numerical approximation of the coupled Burgers'equations.During the whole solution procedure,two different schemes are considered in terms of radial and non-radial basis functions.The time-dependent variable in the first radial scheme is directly considered as the normal space variables to formulate an"isotropic"space-time radial basis function.The second non-radial scheme considered relationship between time-dependent and spacedependent variables.Under such circumstance,we can get a one-step space-time meshless scheme.The numerical findings demonstrate that the proposed meshless schemes are precise,user-friendly,and effective in solving the coupled Burgers'equations.展开更多
In this paper,the forecasting equations of a 2nd-order space-time differential remainder are deduced from the Navier-Stokes primitive equations and Eulerian operator by Taylor-series expansion.Here we introduce a cubi...In this paper,the forecasting equations of a 2nd-order space-time differential remainder are deduced from the Navier-Stokes primitive equations and Eulerian operator by Taylor-series expansion.Here we introduce a cubic spline numerical model(Spline Model for short),which is with a quasi-Lagrangian time-split integration scheme of fitting cubic spline/bicubic surface to all physical variable fields in the atmospheric equations on spherical discrete latitude-longitude mesh.A new algorithm of"fitting cubic spline—time step integration—fitting cubic spline—……"is developed to determine their first-and2nd-order derivatives and their upstream points for time discrete integral to the governing equations in Spline Model.And the cubic spline function and its mathematical polarities are also discussed to understand the Spline Model’s mathematical foundation of numerical analysis.It is pointed out that the Spline Model has mathematical laws of"convergence"of the cubic spline functions contracting to the original functions as well as its 1st-order and 2nd-order derivatives.The"optimality"of the 2nd-order derivative of the cubic spline functions is optimal approximation to that of the original functions.In addition,a Hermite bicubic patch is equivalent to operate on a grid for a 2nd-order derivative variable field.Besides,the slopes and curvatures of a central difference are identified respectively,with a smoothing coefficient of 1/3,three-point smoothing of that of a cubic spline.Then the slopes and curvatures of a central difference are calculated from the smoothing coefficient 1/3 and three-point smoothing of that of a cubic spline,respectively.Furthermore,a global simulation case of adiabatic,non-frictional and"incompressible"model atmosphere is shown with the quasi-Lagrangian time integration by using a global Spline Model,whose initial condition comes from the NCEP reanalysis data,along with quasi-uniform latitude-longitude grids and the so-called"shallow atmosphere"Navier-Stokes primitive equations in the spherical coordinates.The Spline Model,which adopted the Navier-Stokes primitive equations and quasi-Lagrangian time-split integration scheme,provides an initial ideal case of global atmospheric circulation.In addition,considering the essentially non-linear atmospheric motions,the Spline Model could judge reasonably well simple points of any smoothed variable field according to its fitting spline curvatures that must conform to its physical interpretation.展开更多
基金supported by the Advance Research Project of Civil Aerospace Technology(Grant No.D020304)National Nat-ural Science Foundation of China(Grant Nos.52205257 and U22B2083).
文摘This paper proposes a new step-by-step Chebyshev space-time spectral method to analyze the force vibration of functionally graded material structures.Although traditional space-time spectral methods can reduce the accuracy mismatch between tem-poral low-order finite difference and spatial high-order discre tization,the ir time collocation points must increase dramatically to solve highly oscillatory solutions of structural vibration,which results in a surge in computing time and a decrease in accuracy.To address this problem,we introduced the step-by-step idea in the space-time spectral method.The Chebyshev polynomials and Lagrange's equation were applied to derive discrete spatial goverming equations,and a matrix projection method was used to map the calculation results of prev ious steps as the initial conditions of the subsequent steps.A series of numerical experiments were carried out.The results of the proposed method were compared with those obtained by traditional space-time spectral methods,which showed that higher accuracy could be achieved in a shorter computation time than the latter in highly oscillatory cases.
基金supported by Beijing Municipal Natural Science Foundation(L222002)the Natural Science Foundation of China(U22B2004).
文摘Existing orthogonal space-time block coding(OSTBC)schemes for backscatter communication systems cannot achieve a full transmission code rate when the tag is equipped with more than two antennas.In this paper,we propose a quasi-orthogonal spacetime block code(QOSTBC)that can achieve a full transmission code rate for backscatter communication systems with a four-antenna tag and then extend the scheme to support tags with 2i antennas.Specifically,we first present the system model for the backscatter system.Next,we propose the QOSTBC scheme to encode the tag signals.Then,we provide the corresponding maximum likelihood detection algorithms to recover the tag signals.Finally,simulation results are provided to demonstrate that our proposed QOSTBC scheme and the detection algorithm can achieve a better transmission code rate or symbol error rate performance for backscatter communication systems compared with benchmark schemes.
基金funded by the Deanship of Graduate Studies and Scientific Research at Jouf University under grant No.(DGSSR-2024-02-02160).
文摘In this paper,we propose a hybrid decode-and-forward and soft information relaying(HDFSIR)strategy to mitigate error propagation in coded cooperative communications.In the HDFSIR approach,the relay operates in decode-and-forward(DF)mode when it successfully decodes the received message;otherwise,it switches to soft information relaying(SIR)mode.The benefits of the DF and SIR forwarding strategies are combined to achieve better performance than deploying the DF or SIR strategy alone.Closed-form expressions for the outage probability and symbol error rate(SER)are derived for coded cooperative communication with HDFSIR and energy-harvesting relays.Additionally,we introduce a novel normalized log-likelihood-ratio based soft estimation symbol(NL-SES)mapping technique,which enhances soft symbol accuracy for higher-order modulation,and propose a model characterizing the relationship between the estimated complex soft symbol and the actual high-order modulated symbol.Further-more,the hybrid DF-SIR strategy is extended to a distributed Alamouti space-time-coded cooperative network.To evaluate the~performance of the proposed HDFSIR strategy,we implement extensive Monte Carlo simulations under varying channel conditions.Results demonstrate significant improvements with the hybrid technique outperforming individual DF and SIR strategies in both conventional and distributed Alamouti space-time coded cooperative networks.Moreover,at a SER of 10^(-3),the proposed NL-SES mapping demonstrated a 3.5 dB performance gain over the conventional averaging one,highlighting its superior accuracy in estimating soft symbols for quadrature phase-shift keying modulation.
文摘In this article,several kinds of novel exact waves solutions of three well-known different space-time fractional nonlinear coupled waves dynamical models are constructed with the aid of simpler and effective improved auxiliary equation method.Firstly we will investigate space-time fractional coupled Boussinesq-Burger dynamical model,which is used to model the propagation of water waves in shallow sea and harbor,and has many applications in ocean engineering.Secondly,we will investigate the space-time fractional coupled Drinfeld-SokolovWilson equation which is used to characterize the nonlinear surface gravity waves propagation over horizontal seabed.Thirdly,we will investigate the space-time-space fractional coupled Whitham-Broer-Kaup equation which is used to model the shallow water waves in a porous medium near a dam.We obtained different solutions in terms of trigonometric,hyperbolic,exponential and Jacobi elliptic functions.Furthermore,graphics are plotted to explain the different novel structures of obtained solutions such as multi solitons interaction,periodic soliton,bright and dark solitons,Kink and anti-Kink solitons,breather-type waves and so on,which have applications in ocean engineering,fluid mechanics and other related fields.We hope that our results obtained in this article will be useful to understand many novel physical phenomena in applied sciences and other related fields.
基金supported by the Horizontal Scientific Research Funds in Huaibei Normal University(No.2024340603000006)the Science and Technology General Project of Jiangxi Provincial Department of Education(Nos.GJJ2203203,GJJ2203213)。
文摘This study introduces a novel single-layer meshless method,the space-time collocation method based on multiquadric-radial basis functions(MQ-RBF),for solving the Benjamin-Bona-Mahony-Burgers(BBMB)equation.By reconstructing the time variable as a space variable,this method establishes a combined space-time structure that can eliminate the two-step computational process required in traditional grid methods.By introducing shape parameteroptimized MQ-RBF,high-precision discretization of the nonlinear,dispersive,and dissipative terms in the BBMB equation is achieved.The numerical experiment section validates the effectiveness of the proposed method through three benchmark examples.This method shows significant advantages in computational efficiency,providing a new numerical tool for engineering applications in fields such as shallow water wave dynamics.
基金Supported by the Natural Science Foundation of Sichuan Education Committee under Grant No.08ZA038
文摘The generalized Thirring model with impurity coupling is defined on two-dimensional noncommutativespace-time,a modified propagator and free energy are derived by means of functional integrals method.Moreover,quantum fluctuations and excitation energies are calculated on two-dimensional black hole and soliton background.
基金supported by the National Natural Science Foundation of China(52372310)the State Key Laboratory of Advanced Rail Autonomous Operation(RAO2023ZZ001)+1 种基金the Fundamental Research Funds for the Central Universities(2022JBQY001)Beijing Laboratory of Urban Rail Transit.
文摘The emerging virtual coupling technology aims to operate multiple train units in a Virtually Coupled Train Set(VCTS)at a minimal but safe distance.To guarantee collision avoidance,the safety distance should be calculated using the state-of-the-art space-time separation principle that separates the Emergency Braking(EB)trajectories of two successive units during the whole EB process.In this case,the minimal safety distance is usually numerically calculated without an analytic formulation.Thus,the constrained VCTS control problem is hard to address with space-time separation,which is still a gap in the existing literature.To solve this problem,we propose a Distributed Economic Model Predictive Control(DEMPC)approach with computation efficiency and theoretical guarantee.Specifically,to alleviate the computation burden,we transform implicit safety constraints into explicitly linear ones,such that the optimal control problem in DEMPC is a quadratic programming problem that can be solved efficiently.For theoretical analysis,sufficient conditions are derived to guarantee the recursive feasibility and stability of DEMPC,employing compatibility constraints,tube techniques and terminal ingredient tuning.Moreover,we extend our approach with globally optimal and distributed online EB configuration methods to shorten the minimal distance among VCTS.Finally,experimental results demonstrate the performance and advantages of the proposed approaches.
文摘In our investigation,we explore the quantum dynamics of charge-free scalar particles through the Klein–Gordon equation within the framework of rainbow gravity,considering the Bonnor–Melvin-Lambda(BML)space-time background.The BML solution is characterized by the magnetic field strength along the axis of the symmetry direction which is related to the cosmological constantΛand the topological parameterαof the geometry.The behavior of charge-free scalar particles described by the Klein–Gordon equation is investigated,utilizing two sets of rainbow functions:(i)f(χ)=■,h(χ)=1 and(ii)f(χ)=1,h(χ)=1+βХ/2.Here 0<(Х=■)≤1 with E representing the particle's energy,Ep is the Planck's energy,andβis the rainbow parameter.We obtain the approximate analytical solutions for the scalar particles and conduct a thorough analysis of the obtained results.Afterwards,we study the quantum dynamics of quantum oscillator fields within this BML space-time,employing the Klein–Gordon oscillator.Here also,we choose the same sets of rainbow functions and obtain the approximate eigenvalue solution for the oscillator fields.Notably,we demonstrate that the relativistic approximate energy profiles of charge-free scalar particles and oscillator fields get influenced by the topology of the geometry and the cosmological constant.Furthermore,we show that the energy profiles of scalar particles receive modifications from the rainbow parameter and the quantum oscillator fields by both the rainbow parameter and the frequency of oscillation.
基金supported by the Shenzhen sustainable development project:KCXFZ 20201221173013036 and the National Natural Science Foundation of China(91746107).
文摘In this paper,we mainly discuss a discrete estimation of the average differential entropy for a continuous time-stationary ergodic space-time random field.By estimating the probability value of a time-stationary random field in a small range,we give an entropy estimation and obtain the average entropy estimation formula in a certain bounded space region.It can be proven that the estimation of the average differential entropy converges to the theoretical value with a probability of 1.In addition,we also conducted numerical experiments for different parameters to verify the convergence result obtained in the theoretical proofs.
基金supported in part by NIH R01 NS100531,R01 NS103481NIH R21NS130241(to LD)+3 种基金Merit Review Award I01 BX002356,I01 BX003705 from the U.S.Department of Veterans AffairsIndiana Spinal Cord and Brain Injury Research Foundation(No.19919)Mari Hulman George Endowment Funds(to XMX)Indiana Spinal Cord&Brain Injury Research Fund from ISDH(to NKL and LD)。
文摘Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal cord.Here we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord injury.We report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal directions.Such Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder functions.Importantly,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord injury.These findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.
基金supported by the National Natural Science Foundation of China (No.61971412)。
文摘Underwater monopulse space-time adaptive track-before-detect method,which combines space-time adaptive detector(STAD)and the track-before-detect algorithm based on dynamic programming(DP-TBD),denoted as STAD-DP-TBD,can effectively detect low-speed weak targets.However,due to the complexity and variability of the underwater environment,it is difficult to obtain sufficient secondary data,resulting in a serious decline in the detection and tracking performance,and leading to poor robustness of the algorithm.In this paper,based on the adaptive matched filter(AMF)test and the RAO test,underwater monopulse AMF-DP-TBD algorithm and RAO-DP-TBD algorithm which incorporate persymmetry and symmetric spectrum,denoted as PSAMF-DP-TBD and PS-RAO-DP-TBD,are proposed and compared with the AMF-DP-TBD algorithm and RAO-DP-TBD algorithm based on persymmetry array,denoted as P-AMF-DP-TBD and P-RAO-DP-TBD.The simulation results show that the four methods can work normally with sufficient secondary data and slightly insufficient secondary data,but when the secondary data is severely insufficient,the P-AMF-DP-TBD and P-RAO-DP-TBD algorithms has failed while the PSAMF-DP-TBD and PS-RAO-DP-TBD algorithms still have good detection and tracking capabilities.
基金supported by the National Natural Science Foundation of China,Nos.82204360(to HM)and 82270411(to GW)National Science and Technology Innovation 2030 Major Program,No.2021ZD0200900(to YL)。
文摘Traumatic brain injury involves complex pathophysiological mechanisms,among which oxidative stress significantly contributes to the occurrence of secondary injury.In this study,we evaluated hypidone hydrochloride(YL-0919),a self-developed antidepressant with selective sigma-1 receptor agonist properties,and its associated mechanisms and targets in traumatic brain injury.Behavioral experiments to assess functional deficits were followed by assessment of neuronal damage through histological analyses and examination of blood-brain barrier permeability and brain edema.Next,we investigated the antioxidative effects of YL-0919 by assessing the levels of traditional markers of oxidative stress in vivo in mice and in vitro in HT22 cells.Finally,the targeted action of YL-0919 was verified by employing a sigma-1 receptor antagonist(BD-1047).Our findings demonstrated that YL-0919 markedly improved deficits in motor function and spatial cognition on day 3 post traumatic brain injury,while also decreasing neuronal mortality and reversing blood-brain barrier disruption and brain edema.Furthermore,YL-0919 effectively combated oxidative stress both in vivo and in vitro.The protective effects of YL-0919 were partially inhibited by BD-1047.These results indicated that YL-0919 relieved impairments in motor and spatial cognition by restraining oxidative stress,a neuroprotective effect that was partially reversed by the sigma-1 receptor antagonist BD-1047.YL-0919 may have potential as a new treatment for traumatic brain injury.
文摘BACKGROUND At present,the influencing factors of social function in patients with residual depressive symptoms are still unclear.Residual depressive symptoms are highly harmful,leading to low mood in patients,affecting work and interpersonal communication,increasing the risk of recurrence,and adding to the burden on families.Studying the influencing factors of their social function is of great significance.AIM To explore the social function score and its influencing factors in patients with residual depressive symptoms.METHODS This observational study surveyed patients with residual depressive symptoms(case group)and healthy patients undergoing physical examinations(control group).Participants were admitted between January 2022 and December 2023.Social functioning was assessed using the Sheehan Disability Scale(SDS),and scores were compared between groups.Factors influencing SDS scores in patients with residual depressive symptoms were analyzed by applying multiple linear regression while using the receiver operating characteristic curve,and these RESULTS The SDS scores of the 158 patients with depressive symptoms were 11.48±3.26.Compared with the control group,the SDS scores and all items in the case group were higher.SDS scores were higher in patients with relapse,discon-tinuous medication,drug therapy alone,severe somatic symptoms,obvious residual symptoms,and anxiety scores≥8.Disease history,medication compliance,therapy method,and residual symptoms correlated positively with SDS scores(r=0.354,0.414,0.602,and 0.456,respectively).Independent influencing factors included disease history,medication compliance,therapy method,somatic symptoms,residual symptoms,and anxiety scores(P<0.05).The areas under the curve for predicting social functional impairment using these factors were 0.713,0.559,0.684,0.729,0.668,and 0.628,respectively,with sensitivities of 79.2%,61.8%,76.8%,81.7%,63.6%,and 65.5%and specificities of 83.3%,87.5%,82.6%,83.3%,86.7%,and 92.1%,respectively.CONCLUSION The social function scores of patients with residual symptoms of depression are high.They are affected by disease history,medication compliance,therapy method,degree of somatic symptoms,residual symptoms,and anxiety.
基金supported by the NIH (R01NS103481, R01NS111776, and R01NS131489)Indiana Department of Health (ISDH58180)(all to WW)。
文摘Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes following thoracic contusive spinal cord injury. After a 7-day recovery period after spinal cord injury, mice were assigned to either a trained group(10 weeks of voluntary running wheel or forced treadmill exercise) or an untrained group. Bi-weekly assessments revealed that the exercise-trained group, particularly the voluntary wheel exercise subgroup, displayed significantly improved locomotor recovery, more plasticity of dopaminergic and serotonin modulation compared with the untrained group. Additionally, exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury areas across groups, exercise training promoted terminal innervation of descending axons. In summary, voluntary wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury, emphasizing the role of exercise modality in promoting recovery and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.
文摘This paper presents a physically plausible and somewhat illuminating first step in extending the fundamental principles of mechanical stress and strain to space-time. Here the geometry of space-time, encoded in the metric tensor, is considered to be made up of a dynamic lattice of extremely small, localized fields that form a perfectly elastic Lorentz symmetric space-time at the global (macroscopic) scale. This theoretical model of space-time at the Planck scale leads to a somewhat surprising result in which matter waves in curved space-time radiate thermal gravitational energy, as well as an equally intriguing relationship for the anomalous dispersion of light in a gravitational field.
基金supported by the National Key Research and Development Program of China(2016YFE0200400)the Key R&D Program of Shaanxi Province(2017KW-ZD-12)+1 种基金the Postdoctoral Science Foundation of Shaanxi Provincethe Nature Science Foundation of Shaanxi Province
文摘Space-time coding radar has been recently proposed and investigated.It is a radar framework which can perform transmit beamforming at the receiver.However,the range resolution decreases when the number of the transmit element increases.A subarray-based space-time coding(sub-STC)radar is explored to alleviate the range resolution reduction.For the proposed radar configuration,an identical waveform is transmitted and it introduces a small time offset in different subarrays.The multidimensional ambiguity function of sub-STC radar is defined by considering resolutions in multiple domains including the range,Doppler,angle and probing direction.Analyses on properties of the multi-dimensional ambiguity function of the sub-STC radar with regard to the spatial coverage,resolution performance and low sidelobes are also given.Results reveal that the range resolution and low sidelobes performance are improved with the proposed approach.
基金financial support from the JSPS KAKENHI Grant-in-Aid for Scientific Research(B),No.21H02035KAKENHI Grant-in-Aid for Challenging Research(Exploratory),No.21K19017+2 种基金KAKENHI Grant-in-Aid for Transformative Research Areas(B),No.21H05100National Natural Science Foundation of China,No.22409033 and No.22409035Basic and Applied Basic Research Foundation of Guangdong Province,No.2022A1515110470.
文摘Protonic solid oxide electrolysis cells(P-SOECs)are a promising technology for water electrolysis to produce green hydrogen.However,there are still challenges related key materials and anode/electrolyte interface.P-SOECs with Zr-rich electrolyte,called Zr-rich side P-SOECs,possess high thermodynamically stability under high steam concentrations but the large reaction resistances and the current leakage,thus the inferior performances.In this study,an efficient functional interlayer Ba_(0.95)La_(0.05)Fe_(0.8)Zn_(0.2)O_(3-δ)(BLFZ)in-between the anode and the electrolyte is developed.The electrochemical performances of P-SOECs are greatly enhanced because the BLFZ can greatly increase the interface contact,boost anode reaction kinetics,and increase proton injection into electrolyte.As a result,the P-SOEC yields high current density of 0.83 A cm^(-2) at 600℃ in 1.3 Vamong all the reported Zr-rich side cells.This work not only offers an efficient functional interlayer for P-SOECs but also holds the potential to achieve P-SOECs with high performances and long-term stability.
基金supported by the National Natural Science Foundation of China,Nos.82071387(to HT),81971172(to YW)the Natural Science Foundation of Zhejiang Province,China,No.LY22H090012(to HT)the Basic Research Project of Wenzhou City,China,No.Y20220923(to MZ)。
文摘The M1/M2 phenotypic shift of microglia after spinal cord injury plays an important role in the regulation of neuroinflammation during the secondary injury phase of spinal cord injury.Regulation of shifting microglia polarization from M1(neurotoxic and proinflammatory type)to M2(neuroprotective and anti-inflammatory type)after spinal cord injury appears to be crucial.Tryptanthrin possesses an anti-inflammatory biological function.However,its roles and the underlying molecular mechanisms in spinal cord injury remain unknown.In this study,we found that tryptanthrin inhibited microglia-derived inflammation by promoting polarization to the M2 phenotype in vitro.Tryptanthrin promoted M2 polarization through inactivating the cGAS/STING/NF-κB pathway.Additionally,we found that targeting the cGAS/STING/NF-κB pathway with tryptanthrin shifted microglia from the M1 to M2 phenotype after spinal cord injury,inhibited neuronal loss,and promoted tissue repair and functional recovery in a mouse model of spinal cord injury.Finally,using a conditional co-culture system,we found that microglia treated with tryptanthrin suppressed endoplasmic reticulum stress-related neuronal apoptosis.Taken together,these results suggest that by targeting the cGAS/STING/NF-κB axis,tryptanthrin attenuates microglia-derived neuroinflammation and promotes functional recovery after spinal cord injury through shifting microglia polarization to the M2 phenotype.
基金the Science and Technology Research Project of Henan Province (242102231052)the Key Scientific Research Plan of Colleges and Universities in Henan Province (23B140006)the Natural Science Foundation of Jiangxi Province (20224BAB201018)。
文摘In this paper,a simple direct space-time semi-analytical meshless scheme is proposed for the numerical approximation of the coupled Burgers'equations.During the whole solution procedure,two different schemes are considered in terms of radial and non-radial basis functions.The time-dependent variable in the first radial scheme is directly considered as the normal space variables to formulate an"isotropic"space-time radial basis function.The second non-radial scheme considered relationship between time-dependent and spacedependent variables.Under such circumstance,we can get a one-step space-time meshless scheme.The numerical findings demonstrate that the proposed meshless schemes are precise,user-friendly,and effective in solving the coupled Burgers'equations.
文摘In this paper,the forecasting equations of a 2nd-order space-time differential remainder are deduced from the Navier-Stokes primitive equations and Eulerian operator by Taylor-series expansion.Here we introduce a cubic spline numerical model(Spline Model for short),which is with a quasi-Lagrangian time-split integration scheme of fitting cubic spline/bicubic surface to all physical variable fields in the atmospheric equations on spherical discrete latitude-longitude mesh.A new algorithm of"fitting cubic spline—time step integration—fitting cubic spline—……"is developed to determine their first-and2nd-order derivatives and their upstream points for time discrete integral to the governing equations in Spline Model.And the cubic spline function and its mathematical polarities are also discussed to understand the Spline Model’s mathematical foundation of numerical analysis.It is pointed out that the Spline Model has mathematical laws of"convergence"of the cubic spline functions contracting to the original functions as well as its 1st-order and 2nd-order derivatives.The"optimality"of the 2nd-order derivative of the cubic spline functions is optimal approximation to that of the original functions.In addition,a Hermite bicubic patch is equivalent to operate on a grid for a 2nd-order derivative variable field.Besides,the slopes and curvatures of a central difference are identified respectively,with a smoothing coefficient of 1/3,three-point smoothing of that of a cubic spline.Then the slopes and curvatures of a central difference are calculated from the smoothing coefficient 1/3 and three-point smoothing of that of a cubic spline,respectively.Furthermore,a global simulation case of adiabatic,non-frictional and"incompressible"model atmosphere is shown with the quasi-Lagrangian time integration by using a global Spline Model,whose initial condition comes from the NCEP reanalysis data,along with quasi-uniform latitude-longitude grids and the so-called"shallow atmosphere"Navier-Stokes primitive equations in the spherical coordinates.The Spline Model,which adopted the Navier-Stokes primitive equations and quasi-Lagrangian time-split integration scheme,provides an initial ideal case of global atmospheric circulation.In addition,considering the essentially non-linear atmospheric motions,the Spline Model could judge reasonably well simple points of any smoothed variable field according to its fitting spline curvatures that must conform to its physical interpretation.
