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Solutions to SU(n+1)Toda systems with cone singularities via toric curves on compact Riemann surfaces
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作者 Jingyu Mu Yiqian Shi and Bin Xu 《中国科学技术大学学报》 北大核心 2025年第5期2-13,1,I0001,共14页
On a compact Riemann surface with finite punctures P_(1),…P_(k),we define toric curves as multivalued,totallyunramified holomorphic maps to P^(n)with monodromy in a maximal torus of PSU(n+1).Toric solutions to SU(n+1... On a compact Riemann surface with finite punctures P_(1),…P_(k),we define toric curves as multivalued,totallyunramified holomorphic maps to P^(n)with monodromy in a maximal torus of PSU(n+1).Toric solutions to SU(n+1)Todasystems on X\{P_(1);…;P_(k)}are recognized by the associated toric curves in.We introduce character n-ensembles as-tuples of meromorphic one-forms with simple poles and purely imaginary periods,generating toric curves on minus finitelymany points.On X,we establish a correspondence between character-ensembles and toric solutions to the SU(n+1)system with finitely many cone singularities.Our approach not only broadens seminal solutions with two conesingularities on the Riemann sphere,as classified by Jost-Wang(Int.Math.Res.Not.,2002,(6):277-290)andLin-Wei-Ye(Invent.Math.,2012,190(1):169-207),but also advances beyond the limits of Lin-Yang-Zhong’s existencetheorems(J.Differential Geom.,2020,114(2):337-391)by introducing a new solution class. 展开更多
关键词 SU(n+1)Toda system regular singularity unitary curve toric solution character ensemble
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MEROMORPHIC SOLUTIONS OF CERTAIN TYPES OF DIFFERENTIAL EQUATIONS WITH K EXPONENTIAL TERMS
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作者 Minfeng CHEN Meili LIANG Zongsheng GAO 《Acta Mathematica Scientia》 2025年第3期1155-1168,共14页
In this article,we study the meromorphic solutions of the following non-linear differential equation■where n and k are integers with n≥k≥3,P_(d)(z,f)is a differential polynomial in f of degree d≤n−1,p′js andα′j... In this article,we study the meromorphic solutions of the following non-linear differential equation■where n and k are integers with n≥k≥3,P_(d)(z,f)is a differential polynomial in f of degree d≤n−1,p′js andα′js are non-zero constants.We obtain the expressions of meromorphic solutions of the above equations under some restrictions onα′js.Some examples are given to illustrate the possibilities of our results. 展开更多
关键词 meromorphic solution non-linear differential equation Nevanlinna theory ex-ponential differential polynomial
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∑-Shaped Connected Component of Positive Solutions for One- Dimensional Prescribed Mean Curvature Equation in Minkowski Space
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作者 QI Tiaoyan LU Yanqiong 《Wuhan University Journal of Natural Sciences》 2025年第3期241-252,共12页
In this work,we demonstrate that the existence of an Z-shaped connected component within the set of positive solutions for the one-dimensional prescribed mean curvature equation in Minkowski space■with boundary condi... In this work,we demonstrate that the existence of an Z-shaped connected component within the set of positive solutions for the one-dimensional prescribed mean curvature equation in Minkowski space■with boundary conditions having parameter in two cases f(O)=0 and f(0)>0 by using upper and lower solution method,where λ>0 is a parameter,f∈C^(2)([0,∞),R)is monotonically increasing and lim_(μ→1)^(f(u)/1-u=0,h∈C^(1)([0,1],(0,∞))is a nonincreasing function and h(t)>1. 展开更多
关键词 boundary conditions with parameters positive solutions the upper and lower solution method asymptotic property
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A POSITIVE SOLUTION FOR QUASILINEAR SCHRÖDINGER-POISSON SYSTEM WITH CRITICAL EXPONENT
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作者 Lanxin HUANG Jiabao SU 《Acta Mathematica Scientia》 2025年第4期1247-1264,共18页
In this paper,we study the quasilinear Schrödinger-Poisson system with critical Sobolev exponent {-△_(p)u+|u|^(p-2)u=|u|^p^(*-2)u+ph(x)|u|^(q-2)u in R^(3),-△Φt(x)|u|^(p) in R^(3) where μ>0,3/2<p<3,p... In this paper,we study the quasilinear Schrödinger-Poisson system with critical Sobolev exponent {-△_(p)u+|u|^(p-2)u=|u|^p^(*-2)u+ph(x)|u|^(q-2)u in R^(3),-△Φt(x)|u|^(p) in R^(3) where μ>0,3/2<p<3,p≤q<p^(3)=3p/3-p and △_(p)u=div(|▽u|^(p-2)▽u)Under certain assumptions on the functions l and h, we employ the mountain pass theorem to establish the existence of positive solutions for this system. 展开更多
关键词 quasilinear Schrodinger-Poisson system variational methods critical growth positive solution
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The Tamed Euler Method for Random Periodic Solution of Semilinear SDEs with One-sided Lipschitz Coefficient
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作者 GUO Yujia NIU Yuanling 《数学理论与应用》 2025年第2期22-39,共18页
This paper aims to investigate the tamed Euler method for the random periodic solution of semilinear SDEs with one-sided Lipschitz coefficient.We introduce a novel approach to analyze mean-square error bounds of the n... This paper aims to investigate the tamed Euler method for the random periodic solution of semilinear SDEs with one-sided Lipschitz coefficient.We introduce a novel approach to analyze mean-square error bounds of the novel schemes,without relying on a priori high-order moment bound of the numerical approximation.The expected order-one mean square convergence is attained for the proposed scheme.Moreover,a numerical example is presented to verify our theoretical analysis. 展开更多
关键词 Tamed Euler method Random periodic solution one-sided Lipschitz coefficient Order-one mean square convergence
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All entire solutions of Fermat type difference-differential equations of one variable
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作者 XU Ling LUO Run-zi CAO Ting-bin 《Applied Mathematics(A Journal of Chinese Universities)》 2025年第3期509-522,共14页
The main purpose of this paper is to try to find all entire solutions of the Fermat type difference-differential equation[p1(z)f(z+c)]^(2)+[p2(z)f(z)+p3(z)f′(z)]^(2)=p(z);or[p1(z)f(z)]^(2)+[p2(z)f′(z)+p3(z)f(z+c)]^(... The main purpose of this paper is to try to find all entire solutions of the Fermat type difference-differential equation[p1(z)f(z+c)]^(2)+[p2(z)f(z)+p3(z)f′(z)]^(2)=p(z);or[p1(z)f(z)]^(2)+[p2(z)f′(z)+p3(z)f(z+c)]^(2)=p(z)or[p1(z)f′(z)]^(2)+[p2(z)f(z+c)+p3(z)f(z)]^(2)=p(z);where c is a nonzero complex number,p1;p2 and p3 are polynomials in C satisfying p1p3■0;and p is a nonzero irreducible polynomial in C. 展开更多
关键词 difference equations difference-differential equation Fermat type equation entire solutions
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The N-soliton solutions of the three-component coupled nonlinear Hirota equations based on Riemann-Hilbert method
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作者 Xin Wang Zhi-Hui Zhang 《Chinese Physics B》 2025年第9期10-20,共11页
In order to more accurately and effectively consider the propagation process of solitons in electromagnetic pulse waves and make full use of wavelength division multiplexing,we study a class of high-order three-compon... In order to more accurately and effectively consider the propagation process of solitons in electromagnetic pulse waves and make full use of wavelength division multiplexing,we study a class of high-order three-component Hirota equations by the Riemann-Hilbert method.Under zero boundary conditions and given initial conditions q_(j)(x,0),the N-soliton solutions of the equations are obtained by constructing and solving Riemann-Hilbert problems based on matrix spectral problem.Specifically,we discuss the cases of N=1,2,analyze the dynamical properties of 1-soliton and 2-soliton solutions through numerical simulations,and summarize the effect of integrable perturbations and spectral parameters on soliton motion. 展开更多
关键词 coupled Hirota equation soliton solutions Riemann-Hilbert problem matrix spectral problem
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High Energy Normalized Solutions for the Schrodinger Equations with Exponential Critical Growth
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作者 ZHANG Xiao-cang XULi-ping 《Chinese Quarterly Journal of Mathematics》 2025年第1期1-19,共19页
In this paper,we study high energy normalized solutions for the following Schr?dinger equation{-Δu+V(x)u+λu=f(u),in R^(2),∫_(R^(2))|u|^(2)dx=c,where c>0,λ∈R will appear as a Lagrange multiplier,V(x)=ω|x|2 rep... In this paper,we study high energy normalized solutions for the following Schr?dinger equation{-Δu+V(x)u+λu=f(u),in R^(2),∫_(R^(2))|u|^(2)dx=c,where c>0,λ∈R will appear as a Lagrange multiplier,V(x)=ω|x|2 represents a trapping potential,and f has an exponential critical growth.Under the appropriate assumptions of f,we have obtained the existence of normalized solutions to the above Schr?dinger equation by introducing a variational method.And these solutions are also high energy solutions with positive energy. 展开更多
关键词 High energy normalized solutions Schrodinger equation Trapping potential Exponential critical growth Variational method
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YOANTION:Pioneering advanced dyeing&finishing solutions
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《China Textile》 2025年第5期59-59,共1页
Yoantion Industrial INC.,LTD.is a listed company Stock Code 301053 specializing in high-end dyeing and finishing equipment.It serves as the vice president unit of the China Textile Machinery Association and the vice p... Yoantion Industrial INC.,LTD.is a listed company Stock Code 301053 specializing in high-end dyeing and finishing equipment.It serves as the vice president unit of the China Textile Machinery Association and the vice president unit of the China Dyeing and Printing Association.The company has been awarded numerous honors including National High-tech Enterprise and National Stenter Development Base.Its leading products are well-received both domestically and internationally. 展开更多
关键词 advanced dyeing China Textile Machinery Association vice president unit national stenter development base finishing solutions finishing equipment national high tech enterprise high end dyeing
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New criteria on the existence and global exponential stability of periodic solutions for quaternion-valued cellular neural networks
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作者 LI Ai-ling ZHOU Zheng ZHANG Zheng-qiu 《Applied Mathematics(A Journal of Chinese Universities)》 2025年第3期523-542,共20页
In this paper,a class of quaternion-valued cellular neural networks(QVCNNS)with time-varying delays are considered.Combining graph theory with the continuation theorem of Mawhin’s coincidence degree theory as well as... In this paper,a class of quaternion-valued cellular neural networks(QVCNNS)with time-varying delays are considered.Combining graph theory with the continuation theorem of Mawhin’s coincidence degree theory as well as Lyapunov functional method,we establish new criteria on the existence and exponential stability of periodic solutions for QVCNNS by removing the assumptions for the boundedness on the activation functions and the assumptions that the values of the activation functions are zero at origin.Hence,our results are less conservative and new. 展开更多
关键词 the existence of periodic solutions exponential stability quaternion-valued cellular neural networks combining graph theory with Mawhin’s continuation theorem of coincidence degree theory Lyapunov function method inequality techniques
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Effect of two-step solid solution on microstructure andδphase precipitation of Inconel 718 alloy 被引量:2
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作者 Enyu Liu Qingshuang Ma +5 位作者 Xintong Li Aoxue Gao Jing Bai Liming Yu Qiuzhi Gao Huijun Li 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第10期2199-2207,共9页
Inconel 718 is the most popular nickel-based superalloy and is extensively used in aerospace,automotive,and energy indus-tries owing to its extraordinary thermomechanical properties.The effects of different two-step s... Inconel 718 is the most popular nickel-based superalloy and is extensively used in aerospace,automotive,and energy indus-tries owing to its extraordinary thermomechanical properties.The effects of different two-step solid solution treatments on microstructure andδphase precipitation of Inconel 718 alloy were studied,and the transformation mechanism fromγ″metastable phase toδphase was clarified.The precipitates were statistically analyzed by X-ray diffractometry.The results show that theδphase content firstly increased,and then decreased with the temperature of the second-step solid solution.The changes in microstructure andδphase were studied by scanning electron microscopy and transmission electron microscopy.An intragranularδphase formed in Inconel 718 alloy at the second-[100]_(δ)[011]γ step solid solution temperature of 925℃,and its orientation relationship withγmatrix was determined as//and(010)_(δ)//(111)γ.Furthermore,the Vickers hardness of different heat treatment samples was measured,and the sample treated by second-step solid solution at 1010℃ reached the maximum hardness of HV 446.84. 展开更多
关键词 Inconel 718 alloy two-step solid solution treatment δphase γ″-δtransformation
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Semi-analytical Solutions for Wellbores with Graded Skin Zones in Poroelastic Media 被引量:1
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作者 Zhiqiang Fan Zhihe Jin 《Acta Mechanica Solida Sinica》 SCIE EI CSCD 2024年第3期385-395,共11页
In analyzing the complex interaction between the wellbore and the reservoir formation,the hydromechanical properties of the region proximal to the wellbore,referred to as the“wellbore skin zone”,play a pivotal role ... In analyzing the complex interaction between the wellbore and the reservoir formation,the hydromechanical properties of the region proximal to the wellbore,referred to as the“wellbore skin zone”,play a pivotal role in determining flow dynamics and the resulting formation deformation.Existing models of the wellbore skin zone generally assume a constant permeability throughout,resulting in a sharp permeability discontinuity at the skin-reservoir interface.This paper introduces a model for a wellbore with a continuously graded skin zone of finite thickness within a poroelastic medium.Analytical solutions are derived using the Laplace transform method,addressing both positive and negative skin zones.Numerical results are presented to illustrate the effects of graded permeability/skin zone thickness on pore pressures and stresses around a wellbore.The results highlight a distinct divergence in stress and pore pressure fields when comparing wellbores with negative skin zones to those with positive skin zones or no skin at all. 展开更多
关键词 POROELASTIC Graded permeability Analytical solution Wellbore Skin zone
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Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy 被引量:1
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作者 Xin Zhou Dan Ma +7 位作者 Yi-Xiang He Jing Jin Hong-Lian Wang Yun-Feng Wang Fan Yang Jian-Qin Liu Jie Chen Zhi Li 《World Journal of Gastroenterology》 SCIE CAS 2025年第1期110-125,共16页
BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.... BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway. 展开更多
关键词 Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis
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Porous-DeepONet:Learning the Solution Operators of Parametric Reactive Transport Equations in Porous Media
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作者 Pan Huang Yifei Leng +1 位作者 Cheng Lian Honglai Liu 《Engineering》 SCIE EI CAS CSCD 2024年第8期94-103,共10页
Reactive transport equations in porous media are critical in various scientific and engineering disciplines,but solving these equations can be computationally expensive when exploring different scenarios,such as varyi... Reactive transport equations in porous media are critical in various scientific and engineering disciplines,but solving these equations can be computationally expensive when exploring different scenarios,such as varying porous structures and initial or boundary conditions.The deep operator network(DeepONet)has emerged as a popular deep learning framework for solving parametric partial differential equations.However,applying the DeepONet to porous media presents significant challenges due to its limited capability to extract representative features from intricate structures.To address this issue,we propose the Porous-DeepONet,a simple yet highly effective extension of the DeepONet framework that leverages convolutional neural networks(CNNs)to learn the solution operators of parametric reactive transport equations in porous media.By incorporating CNNs,we can effectively capture the intricate features of porous media,enabling accurate and efficient learning of the solution operators.We demonstrate the effectiveness of the Porous-DeepONet in accurately and rapidly learning the solution operators of parametric reactive transport equations with various boundary conditions,multiple phases,and multiphysical fields through five examples.This approach offers significant computational savings,potentially reducing the computation time by 50–1000 times compared with the finite-element method.Our work may provide a robust alternative for solving parametric reactive transport equations in porous media,paving the way for exploring complex phenomena in porous media. 展开更多
关键词 Porous media Reactive transport solution operator Deeponet Neural network
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Semi-analytical solution for mechanical analysis of tunnels crossing strike-slip fault zone considering nonuniform fault displacement and uncertain fault plane position
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作者 YANG Heng-hong WANG Ming-nian +1 位作者 YU Li ZHANG Xiao 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第6期2116-2136,共21页
The tunnel subjected to strike-slip fault dislocation exhibits severe and catastrophic damage.The existing analysis models frequently assume uniform fault displacement and fixed fault plane position.In contrast,post-e... The tunnel subjected to strike-slip fault dislocation exhibits severe and catastrophic damage.The existing analysis models frequently assume uniform fault displacement and fixed fault plane position.In contrast,post-earthquake observations indicate that the displacement near the fault zone is typically nonuniform,and the fault plane position is uncertain.In this study,we first established a series of improved governing equations to analyze the mechanical response of tunnels under strike-slip fault dislocation.The proposed methodology incorporated key factors such as nonuniform fault displacement and uncertain fault plane position into the governing equations,thereby significantly enhancing the applicability range and accuracy of the model.In contrast to previous analytical models,the maximum computational error has decreased from 57.1%to 1.1%.Subsequently,we conducted a rigorous validation of the proposed methodology by undertaking a comparative analysis with a 3D finite element numerical model,and the results from both approaches exhibited a high degree of qualitative and quantitative agreement with a maximum error of 9.9%.Finally,the proposed methodology was utilized to perform a parametric analysis to explore the effects of various parameters,such as fault displacement,fault zone width,fault zone strength,the ratio of maximum fault displacement of the hanging wall to the footwall,and fault plane position,on the response of tunnels subjected to strike-slip fault dislocation.The findings indicate a progressive increase in the peak internal forces of the tunnel with the rise in fault displacement and fault zone strength.Conversely,an augmentation in fault zone width is found to contribute to a decrease in the peak internal forces.For example,for a fault zone width of 10 m,the peak values of bending moment,shear force,and axial force are approximately 46.9%,102.4%,and 28.7% higher,respectively,compared to those observed for a fault zone width of 50 m.Furthermore,the position of the peak internal forces is influenced by variations in the ratio of maximum fault displacement of the hanging wall to footwall and the fault plane location,while the peak values of shear force and axial force always align with the fault plane.The maximum peak internal forces are observed when the footwall exclusively bears the entirety of the fault displacement,corresponding to a ratio of 0:1.The peak values of bending moment,shear force,and axial force for the ratio of 0:1 amount to approximately 123.8%,148.6%,and 111.1% of those for the ratio of 0.5:0.5,respectively. 展开更多
关键词 strike-slip fault tunnel engineering semi-analytical solution fault zone width nonuniform fault displacement uncertain fault plane position
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Unilateral Global Bifurcation and One-Sign Solutions for Kirchhoff Type Problem inR^(N)
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作者 SHEN Wenguo 《Wuhan University Journal of Natural Sciences》 CAS CSCD 2024年第4期365-373,共9页
In this paper,we study the following Kirchhoff type problem:{-M(∫_(R^(N))|▽u|^(2)dx)△u=λa(x)f(u),x∈R^(N),u=0 as|x|→+∞.Unilateral global bifurcation result is established for this problem.As applications of the ... In this paper,we study the following Kirchhoff type problem:{-M(∫_(R^(N))|▽u|^(2)dx)△u=λa(x)f(u),x∈R^(N),u=0 as|x|→+∞.Unilateral global bifurcation result is established for this problem.As applications of the bifurcation result,we determine the intervals ofλfor the existence,nonexistence,and exact multiplicity of one-sign solutions for this problem. 展开更多
关键词 unilateral global bifurcation one-sign solutions Kirchhoff type problem
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Existence of Solution to a Class of Elliptic Equations with Lower Order Terms and Variable Exponents
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作者 Zhongqing LI 《Journal of Mathematical Research with Applications》 CSCD 2024年第6期795-806,共12页
We study a class of nonlinear elliptic equations with nonstandard growth condition.The main feature is that two lower order terms,a non-coercive divergence term divΦ(x,u)and a gradient term H(x,u,▽u)with no growth r... We study a class of nonlinear elliptic equations with nonstandard growth condition.The main feature is that two lower order terms,a non-coercive divergence term divΦ(x,u)and a gradient term H(x,u,▽u)with no growth restriction on u,appear simultaneously in the variable exponents setting.These characteristics prevent us from directly obtaining the existence of solutions by employing the classical theory on existence results.By choosing some appropriate test functions in the perturbed problem,some a priori estimates are obtained under the variable exponent framework.Based on these estimates,we prove the almost everywhere convergence of the gradient sequence{▽u^(ε)}_(ε),which helps to pass to the limit to find a weak solution. 展开更多
关键词 elliptic equations nonstandard growth condition lower order terms weak solutions
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Ascorbic acid-induced porous iodide layer for a high-purity two-step solution-processed tin-lead mixed perovskite photodetector 被引量:2
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作者 Liansong Liu Fengren Cao +3 位作者 Liukang Bian Meng Wang Haoxuan Sun Liang Li 《Journal of Materials Science & Technology》 2025年第7期227-232,共6页
Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method mor... Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method more easily controls the crystallization rate and is suitable for preparing large-area per-ovskite devices.However,the residual low-conductivity iodide layer in the two-step method can affect carrier transport and device stability,and the different crystallization rates of Sn-and Pb-based per-ovskites may result in poor film quality.Therefore,Sn-Pb mixed perovskites are mainly prepared by a one-step method.Herein,a MAPb_(0.5)Sn_(0.5)I_(3)-based self-powered photodetector without a hole transport layer is fabricated by a two-step method.By adjusting the concentration of the ascorbic acid(AA)addi-tive,the final perovskite film exhibited a pure phase without residues,and the optimal device exhibited a high responsivity(0.276 A W^(-1)),large specific detectivity(2.38×10^(12) Jones),and enhanced stability.This enhancement is mainly attributed to the inhibition of Sn2+oxidation,the control of crystal growth,and the sufficient reaction between organic ammonium salts and bottom halides due to the AA-induced pore structure. 展开更多
关键词 PEROVSKITE SN-PB PHOTODETECTOR Two-step solution method
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Colorectal cancer early screening:Dilemmas and solutions 被引量:2
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作者 Di Wu Qi-Ying Song +4 位作者 Bai-Shu Dai Jie Li Xin-Xin Wang Jia-Yu Liu Tian-Yu Xie 《World Journal of Gastroenterology》 2025年第9期154-160,共7页
Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhan... Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhancing patient prognosis.Obviously,non-participation of asymptomatic individuals in screening programs hampers early diagnosis and may adversely affect long-term outcomes for CRC patients.In this letter,we provide a comprehensive overview of the current status of early screening practices,while also thoroughly examine the dilemmas and potential solutions associated with early screening for CRC.In response to these issues,we proffer a set of recommendations directed at governmental authorities and the general public,which focus on augmenting financial investment,establishing standardized screening protocols,advancing technological capabilities,and bolstering public awareness campaigns.The importance of collaborative efforts from various stakeholders cannot be overstated in the quest to enhance early detection rates and alleviate the societal burden of CRC. 展开更多
关键词 Colorectal cancer Early screening Asymptomatic candidates DILEMMAS solutionS
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Catalytic detoxification of mitoxantrone by graphitic carbon nitride(g-C_(3)N_(4))supported Fe/Pd bimetallic nanoparticles 被引量:1
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作者 Qianyu Xu Haoyang Fu +2 位作者 Jiyuan Gu Liyu Lei Lan Ling 《Journal of Environmental Sciences》 2025年第2期614-624,共11页
The overuse of antibiotics and antitumor drugs has resulted in more and more extensive pollution of water bodies with organic drugs,causing detrimental ecological effects,which have attracted attention towards effecti... The overuse of antibiotics and antitumor drugs has resulted in more and more extensive pollution of water bodies with organic drugs,causing detrimental ecological effects,which have attracted attention towards effective and sustainable methods for antibiotics and antitumor drug degradation.Here,the hybrid nanomaterial(g-C_(3)N_(4)@Fe/Pd)was synthesized and used to remove a kind of both an antibiotic and antitumor drug named mitoxantrone(MTX)with 92.0%removal efficiency,and the MTX removal capacity is 450 mg/g.After exposing to the hybrid material the MTX aqueous solution changed color from dark blue to lighter progressively,and LC-UV results of residual solutions showthat a newpeak at 3.0min(MTX:13.2min)after removal by g-C_(3)N_(4)@Fe/Pd appears,with the simultaneous detection of intermediate products indicating that g-C_(3)N_(4)@Fe/Pd indeed degrades MTX.Detailed mass spectrometric analysis suggests that the nuclear mass ratio decreased from 445.2(M+1H)to 126.0(M+1H),169.1(M+1H),239.2(M+1H),267.3(M+1H),285.2(M+1H),371.4(M+1H)and 415.2(M+1H),and the maximum proportion(5.63%)substance of all degradation products(126.0(M+1H))is 40-100 times less toxic than MTX.A mechanism for the removal and degradation of mitoxantrone was proposed.Besides,actual water experiments confirmed that the maximum removal capacity of MTX by g-C_(3)N_(4)@Fe/Pd is up to 492.4 mg/g(0.02 g/L,10 ppm). 展开更多
关键词 DEGRADATION LC-QTOF-MS Nanoparticles MITOXANTRone Aqueous solution
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