针对目前电池荷电状态(stage of charge,SOC)估计算法存在稳定性差、误差大等缺点,提出一种基于实车云端放电数据的自适应扩展卡尔曼滤波(adaptive extended Kalman filter,AEKF)与长短时记忆(long short term memory,LSTM)融合的算法,...针对目前电池荷电状态(stage of charge,SOC)估计算法存在稳定性差、误差大等缺点,提出一种基于实车云端放电数据的自适应扩展卡尔曼滤波(adaptive extended Kalman filter,AEKF)与长短时记忆(long short term memory,LSTM)融合的算法,预测小动力电动车的电池SOC。首先采用自适应遗忘因子最小二乘法(adaptive forgetting factor recursive least squares,AFFRLS)辨识电池的二阶RC等效电路模型参数。其次,将云端实时采集到的放电数据作为研究目标,通过AEKF-LSTM融合算法对小动力电动车的电池SOC进行预测实验,实验过程中AEKF-LSTM融合算法将当前时刻的端电压、电流、温度以及上一时刻电池的SOC作为输入,以更新的SOC作为输出训练估计模型。最后,将AEKF-LSTM融合算法和单一AEKF算法预测电池SOC的结果与实际SOC值进行比较,实验结果表明,AEKF-LSTM融合算法的均方根误差(root mean square error,RMSE)为0.0058 V,平均绝对误差(mean absolute error,MAE)为0.0041 V,比AEKF算法的RMSE减小0.0087 V,MAE减小0.1164 V,且AEKF-LSTM融合算法的RMSE和MAE均在0.6%以内,证明了该融合算法有较高的估计精度和较强的鲁棒性。展开更多
Neuroinflammation plays an important role in the occurrence and development of neurological diseases.In addition to microglia,the role of astrocytes in neuroinflammation has gradually attracted attention.Photobiomodul...Neuroinflammation plays an important role in the occurrence and development of neurological diseases.In addition to microglia,the role of astrocytes in neuroinflammation has gradually attracted attention.Photobiomodulation(PBM),as a non-invasive treatment,has been shown potential to alleviate inflammation of microglia or astrocytes.In this study,the spatiotemporal regulation and molecular mechanism of PBM on astrocytes were deeply explored by analyzing the effects and genomics at different time points.The results showed that PBM significantly attenuated the upregulation of inflammatory factors and mitochondrial dysfunction in astrocytes under LPS stimulation for 4 h and 24 h.RNA-seq analysis showed that the JAK-STAT pathway played an important role in the early stage of both LPS-induced astrocytic neuroin-flammation and PBM-alleviated astrocytic neuroinflammation.Under PBM treatment,Stat5a translocation to the nucleus and upregulated Socs3 expression were observed in LPS-treated astrocytes,which may inhibit the overactivation of the JAK-STAT inflammatory signaling pathway and thus alleviate astrocyte inflammation.Taken together,this study provides new insight into the molecular mechanism of the potential application of PBM in the treatment of neuroinflammation.展开更多
文摘针对目前电池荷电状态(stage of charge,SOC)估计算法存在稳定性差、误差大等缺点,提出一种基于实车云端放电数据的自适应扩展卡尔曼滤波(adaptive extended Kalman filter,AEKF)与长短时记忆(long short term memory,LSTM)融合的算法,预测小动力电动车的电池SOC。首先采用自适应遗忘因子最小二乘法(adaptive forgetting factor recursive least squares,AFFRLS)辨识电池的二阶RC等效电路模型参数。其次,将云端实时采集到的放电数据作为研究目标,通过AEKF-LSTM融合算法对小动力电动车的电池SOC进行预测实验,实验过程中AEKF-LSTM融合算法将当前时刻的端电压、电流、温度以及上一时刻电池的SOC作为输入,以更新的SOC作为输出训练估计模型。最后,将AEKF-LSTM融合算法和单一AEKF算法预测电池SOC的结果与实际SOC值进行比较,实验结果表明,AEKF-LSTM融合算法的均方根误差(root mean square error,RMSE)为0.0058 V,平均绝对误差(mean absolute error,MAE)为0.0041 V,比AEKF算法的RMSE减小0.0087 V,MAE减小0.1164 V,且AEKF-LSTM融合算法的RMSE和MAE均在0.6%以内,证明了该融合算法有较高的估计精度和较强的鲁棒性。
基金funded in part by the STI2030-Major Projects(2022ZD0212200)Hainan Province Key Area R&D Program(KJRC2023C30)+1 种基金Project of Collaborative Innovation Center of One Health(XTCX2022JKB02)Sanya Yazhou Bay Science and Technology City(SKJC-JYRC-2024-38).
文摘Neuroinflammation plays an important role in the occurrence and development of neurological diseases.In addition to microglia,the role of astrocytes in neuroinflammation has gradually attracted attention.Photobiomodulation(PBM),as a non-invasive treatment,has been shown potential to alleviate inflammation of microglia or astrocytes.In this study,the spatiotemporal regulation and molecular mechanism of PBM on astrocytes were deeply explored by analyzing the effects and genomics at different time points.The results showed that PBM significantly attenuated the upregulation of inflammatory factors and mitochondrial dysfunction in astrocytes under LPS stimulation for 4 h and 24 h.RNA-seq analysis showed that the JAK-STAT pathway played an important role in the early stage of both LPS-induced astrocytic neuroin-flammation and PBM-alleviated astrocytic neuroinflammation.Under PBM treatment,Stat5a translocation to the nucleus and upregulated Socs3 expression were observed in LPS-treated astrocytes,which may inhibit the overactivation of the JAK-STAT inflammatory signaling pathway and thus alleviate astrocyte inflammation.Taken together,this study provides new insight into the molecular mechanism of the potential application of PBM in the treatment of neuroinflammation.
