This work considers a generalized fuzzy fractional smoking model with Caputo gHtypes fractional derivatives upon considering the case of uncertainty quantification.The disease-free equilibrium point and stability of t...This work considers a generalized fuzzy fractional smoking model with Caputo gHtypes fractional derivatives upon considering the case of uncertainty quantification.The disease-free equilibrium point and stability of the equilibrium point have been discussed for the fuzzy nonlinear fractional smoking model.The analytical proofs for the existence and uniqueness of the proposed model are concerned with the help of the fixed-point theorem,Banach contraction,and Schauder theorem.A robust double parametric approach with a generalized transform is used to study the behavior of the fuzzy fractional model in an uncertain context and obtain the convergence analysis of the study in a crisp context.Finally,the obtained results of the proposed model have been validated with the Runge-Kutta method of fourth order in crisp case(s=1,l=O).展开更多
In this manuscript,we consider a stochastic smoking epidemic model from behavioural sciences.Also,we develop a structure preserving numerical method to describe the dynamics of stochastic smoking epidemic model in a h...In this manuscript,we consider a stochastic smoking epidemic model from behavioural sciences.Also,we develop a structure preserving numerical method to describe the dynamics of stochastic smoking epidemic model in a human population.The structural properties of a physical system include positivity,boundedness and dynamical consistency.These properties play a vital role in non-linear dynamics.The solution for nonlinear stochastic models necessitates the conservation of these properties.Unfortunately,the aforementioned properties of the model have not been restored in the existing stochastic methods.Therefore,it is essential to construct a structure preserving numerical method for a reliable analysis of stochastic smoking model.The usual explicit stochastic numerical methods are time-dependent and violate most of the structural properties.In this work,we have developed the implicitly driven explicit method for the solution of stochastic smoking model.It is also proved that the newly developed method sustains all the aforementioned properties of the system.Finally,the convergence analysis of the newly developed method and graphical illustrations are presented.展开更多
A new model of rats with Xueyu Syndrome which was characterized by erythrocyte injury was presented. Observation of morphology and functions of erythrocytes showed that this model could not only be used as a model i...A new model of rats with Xueyu Syndrome which was characterized by erythrocyte injury was presented. Observation of morphology and functions of erythrocytes showed that this model could not only be used as a model in Xueyu Syndrome and Huoxuequyu treatment study, but also be used for screening of drugs with the effect of preventing and treating damage of red blood cells.展开更多
Smoke is the main cause of fire death. In order to minimize the potential danger of smoke hazard, a rational VR based fire training simulator should fully consider all aspects of smoke hazard. In the simulator, the vi...Smoke is the main cause of fire death. In order to minimize the potential danger of smoke hazard, a rational VR based fire training simulator should fully consider all aspects of smoke hazard. In the simulator, the visualization of data based on FDS (Fire Dynamics Simulator) and FED fire dynamic data and volume rendering is further optimized, which can be effectively and quickly applied to virtual fire protection. In addition, a comprehensive smoke hazard assessment model based on FED and FED is established to assess the IHD value of different paths, which represents the safety of different paths, and can be used for evacuation or rescue in virtual training. Taking the case of campus fire drill as an experiment, the research shows the accuracy and effectiveness of smoke assessment based on FDS and FED model. The road force with the highest safety can be selected through the comprehensive model. So the assessment model is proved to be valuable.展开更多
Objective To establish a smoke-induced chronic bronchitis rat model and evaluate the patho-logical change semi-quantitatively, and study the characteristics of the inflammatory cells in the bronchoalveolar lav-age flu...Objective To establish a smoke-induced chronic bronchitis rat model and evaluate the patho-logical change semi-quantitatively, and study the characteristics of the inflammatory cells in the bronchoalveolar lav-age fluid (BALF) in various stages. Methods Chronic bronchitis sequential rat model was established by passively inhaling smoke mixture. Experiments were performed in 30 young male Sprague-Dawley rats, which comprised 5 groups in random, i.e.,4 chronic bronchitis model groups and 1 control group. After stained with hematoxylin and eosin, the specimens were studied by semi-quantitative method to evaluate the morphologic changes in various stages. Meanwhile, the inflammatory cells of the BALF and the activity of myeloperoxidase (MPO) of lung tissue were analysed. Results During the process of the chronic bronchitis, the pathologic score was increasing as time went on, and the typical morphologic changes of chronic bronchitis emerged in the group 7 weeks. The total number of inflammatory cells in BALF was increasing as time went on, correlated with the pathologic scores (P <0.01). And the percentage of lymphocyte increased as well as positively correlated with pathologic scores (P < 0. 05) , whereas that of macrophage decreased and negatively correlated with pathologic scores (P <0. 05). The MPO lever of lung tissue was correlated with the pathologic scores (P < 0. 01). But the percentage of the neutrophil in the BALF was just in a high level during the first week, then it maintained relatively lower. Conclusion Smoke-induced chronic bronchitis is a slowly progressive inflammation process. The model we established is convenient and simple for the longitudinal study on the inflammatory process of chronic bronchitis and the therapy in the early stage. The semi-quantitative evaluation for the pathological change is with much more value. During the inflammatory sequential process of early stage of chronic bronchitis, the cellular characteristics are similar to that of the common chronic inflammation.展开更多
文摘This work considers a generalized fuzzy fractional smoking model with Caputo gHtypes fractional derivatives upon considering the case of uncertainty quantification.The disease-free equilibrium point and stability of the equilibrium point have been discussed for the fuzzy nonlinear fractional smoking model.The analytical proofs for the existence and uniqueness of the proposed model are concerned with the help of the fixed-point theorem,Banach contraction,and Schauder theorem.A robust double parametric approach with a generalized transform is used to study the behavior of the fuzzy fractional model in an uncertain context and obtain the convergence analysis of the study in a crisp context.Finally,the obtained results of the proposed model have been validated with the Runge-Kutta method of fourth order in crisp case(s=1,l=O).
文摘In this manuscript,we consider a stochastic smoking epidemic model from behavioural sciences.Also,we develop a structure preserving numerical method to describe the dynamics of stochastic smoking epidemic model in a human population.The structural properties of a physical system include positivity,boundedness and dynamical consistency.These properties play a vital role in non-linear dynamics.The solution for nonlinear stochastic models necessitates the conservation of these properties.Unfortunately,the aforementioned properties of the model have not been restored in the existing stochastic methods.Therefore,it is essential to construct a structure preserving numerical method for a reliable analysis of stochastic smoking model.The usual explicit stochastic numerical methods are time-dependent and violate most of the structural properties.In this work,we have developed the implicitly driven explicit method for the solution of stochastic smoking model.It is also proved that the newly developed method sustains all the aforementioned properties of the system.Finally,the convergence analysis of the newly developed method and graphical illustrations are presented.
基金This project was supported by the National Natural ScienceFoundation of China (No. 39270826).
文摘A new model of rats with Xueyu Syndrome which was characterized by erythrocyte injury was presented. Observation of morphology and functions of erythrocytes showed that this model could not only be used as a model in Xueyu Syndrome and Huoxuequyu treatment study, but also be used for screening of drugs with the effect of preventing and treating damage of red blood cells.
文摘Smoke is the main cause of fire death. In order to minimize the potential danger of smoke hazard, a rational VR based fire training simulator should fully consider all aspects of smoke hazard. In the simulator, the visualization of data based on FDS (Fire Dynamics Simulator) and FED fire dynamic data and volume rendering is further optimized, which can be effectively and quickly applied to virtual fire protection. In addition, a comprehensive smoke hazard assessment model based on FED and FED is established to assess the IHD value of different paths, which represents the safety of different paths, and can be used for evacuation or rescue in virtual training. Taking the case of campus fire drill as an experiment, the research shows the accuracy and effectiveness of smoke assessment based on FDS and FED model. The road force with the highest safety can be selected through the comprehensive model. So the assessment model is proved to be valuable.
基金Supported by the fund from Shanghai Science and Technology Committee (004119060)
文摘Objective To establish a smoke-induced chronic bronchitis rat model and evaluate the patho-logical change semi-quantitatively, and study the characteristics of the inflammatory cells in the bronchoalveolar lav-age fluid (BALF) in various stages. Methods Chronic bronchitis sequential rat model was established by passively inhaling smoke mixture. Experiments were performed in 30 young male Sprague-Dawley rats, which comprised 5 groups in random, i.e.,4 chronic bronchitis model groups and 1 control group. After stained with hematoxylin and eosin, the specimens were studied by semi-quantitative method to evaluate the morphologic changes in various stages. Meanwhile, the inflammatory cells of the BALF and the activity of myeloperoxidase (MPO) of lung tissue were analysed. Results During the process of the chronic bronchitis, the pathologic score was increasing as time went on, and the typical morphologic changes of chronic bronchitis emerged in the group 7 weeks. The total number of inflammatory cells in BALF was increasing as time went on, correlated with the pathologic scores (P <0.01). And the percentage of lymphocyte increased as well as positively correlated with pathologic scores (P < 0. 05) , whereas that of macrophage decreased and negatively correlated with pathologic scores (P <0. 05). The MPO lever of lung tissue was correlated with the pathologic scores (P < 0. 01). But the percentage of the neutrophil in the BALF was just in a high level during the first week, then it maintained relatively lower. Conclusion Smoke-induced chronic bronchitis is a slowly progressive inflammation process. The model we established is convenient and simple for the longitudinal study on the inflammatory process of chronic bronchitis and the therapy in the early stage. The semi-quantitative evaluation for the pathological change is with much more value. During the inflammatory sequential process of early stage of chronic bronchitis, the cellular characteristics are similar to that of the common chronic inflammation.