A group of competitive people escaping through an exit could lead to the formation of a deadlock, which significantly increases the evacuation time. Such a phenomenon is called the faster-is-slower effect（FIS） and i...A group of competitive people escaping through an exit could lead to the formation of a deadlock, which significantly increases the evacuation time. Such a phenomenon is called the faster-is-slower effect（FIS） and it has been experimentally verified in different systems of particles flowing through an opening. In this paper, the numerical simulation based on discrete element method（DEM） is adopted to study a group of highly competitive people through an exit of varying widths. The FIS effect is observed for a narrow exit whilst it is not observed for the exit wide enough to accommodate two people through it side-by-side. Experimental validation of such a phenomenon with humans is difficult due to ethical issues. The mouse is a kind of self-driven and soft-body creature and it exhibits selfish behaviour under stressed conditions.Particles flowing through an opening in different systems, such as pedestrian flow, animal flow, silo flow, etc. have similar characteristics. Therefore, experimental study is conducted by driving mice to escape through an exit of different widths at varying levels of stimulus. The escape time through a narrow exit（i.e., 2 cm） increases obviously with the increase of stimulus level but it is quite opposite to a wider exit（i.e., 4 cm）. The FIS effect is avoided for an exit wide enough to accommodate two mice passing through it side-by-side. The study illustrates that FIF effect could be effectively prevented for an exit when its width is twice the size of particles.展开更多
We develop a permanent-magnet Zeeman slower with adjustable magnets along the longitudinal and radial directions.Produced by four arrays of cylindrical magnets, the longitudinal magnetic field in the slower is tunable...We develop a permanent-magnet Zeeman slower with adjustable magnets along the longitudinal and radial directions.Produced by four arrays of cylindrical magnets, the longitudinal magnetic field in the slower is tunable if relevant parameters vary, for example, laser detuning or intensity. The proposed Zeeman slower can be reconfigured for Sr atoms. Additionally,we demonstrate that the residual magnetic field produced by the permanent magnets in the magneto-optical trap region can be as small as 0.5 Gs.展开更多
We report a longitudinal Zeeman slower based on ring-shaped permanent magnetic dipoles used for the strontium optical lattice clock. The Zeeman slower is composed of 40 permanent magnets with the same outer diameter b...We report a longitudinal Zeeman slower based on ring-shaped permanent magnetic dipoles used for the strontium optical lattice clock. The Zeeman slower is composed of 40 permanent magnets with the same outer diameter but different inner diameters. The maximum variation of the axial field from its target values is less than 2%. In most parts of the Zeeman slower, the intensity variations of the field in radial spatial distribution are less than 0.1 roT. With this Zeeman slower, the strontium atoms are slowed down to 95m/s, and approximately 2% of the total atoms are slowed down to less than 50m/s.展开更多
Background: Women are thought to be more susceptible to stress than men in a stressful society, and reducing stress is crucial for women to maintain their health. Static stretching (SST) is applied in various fields t...Background: Women are thought to be more susceptible to stress than men in a stressful society, and reducing stress is crucial for women to maintain their health. Static stretching (SST) is applied in various fields to not only increase muscle flexibility but also reduce stress. Additionally, conscious slower breathing (CSB) predominates parasympathetic activity, causing a relaxing effect. These results indicate that combining SST and CSB may be more useful in reducing stress. However, to the best of our knowledge, the effect of this combination remains unclear. Objective: This study aimed to elucidate the effects of the combination of SST and CSB on autonomic activity and stress in adult women. Methods: Eleven healthy Japanese adult female participants performed SST with nonconscious natural breathing for 20 min. The same participants performed SST in combination with CSB (2 s inspiratory and 4 s expiratory) for 20 min on another day. Salivary cortisol and chromogranin A levels were measured before and after stretching as stress markers of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system. The coefficient of variation of the R-R interval (CVR-R) and high-frequency component (HF), which reflect parasympathetic nerve activity, and heart rate and low-frequency component (LF)/HF ratio, which reflect sympathetic nerve activity, were measured before, during, and after stretching. Results: SST decreased cortisol levels but with no significant changes in chromogranin A, heart rate, CVR-R, HF, or LF/HF ratio. The combination of SST and CSB increased CVR-R and HF levels in addition to decreasing cortisol levels but with no significant changes in chromogranin A, heart rate, or LF/HF levels. Conclusion: These results indicate that the combination of SST and CSB may increase parasympathetic activity and reduce stress. However, future randomized controlled trials with larger sample sizes should support this conclusion.展开更多
Chinese outdoor industry is eyeing expansion in the future 10 years though its growth slows a little bit in recent years.China Outdoor Industry Report,released by China Outdoor Association(COA for short) at the Asia O...Chinese outdoor industry is eyeing expansion in the future 10 years though its growth slows a little bit in recent years.China Outdoor Industry Report,released by China Outdoor Association(COA for short) at the Asia Outdoor 2015 held in Nanjing,capital of Jiangsu Province in July,shows that the outdoor core market volume in 2014 reached RMB 17.06展开更多
On Sept. 26, Chana Auto announced that by Sept. 23, after several rounds of selling-off which started at the beginning of 2002, Suzuki’s B shares in Chana, the second largest holding, were reduced to 61.4 million fro...On Sept. 26, Chana Auto announced that by Sept. 23, after several rounds of selling-off which started at the beginning of 2002, Suzuki’s B shares in Chana, the second largest holding, were reduced to 61.4 million from previous 122.5 million, accounting for only 5.003% of the whole. Some experts analyze there are two reasons behind the selling-off of Suzuki’s B shares of Chana: 1. Chana has been active recently in its cooperation with Ford (The initial investment of Chana Ford展开更多
China National Textile & Apparel Council released the latest industry reviews in its mid-year conference that in the first half of 2010,the textile industry kept its stable recovery and the whole situation was goo...China National Textile & Apparel Council released the latest industry reviews in its mid-year conference that in the first half of 2010,the textile industry kept its stable recovery and the whole situation was good;for the anticipation of late half,this industry would continue this tendency but growth speed might slow down.展开更多
As shown in the results of 100 Chinese Economists’ Confi- dence Survey,conducted by China’s Economic Monitoring and Analy- sis Center,National Bureau of Statistics,the confidence index of the economists in the secon...As shown in the results of 100 Chinese Economists’ Confi- dence Survey,conducted by China’s Economic Monitoring and Analy- sis Center,National Bureau of Statistics,the confidence index of the economists in the second quarter of 2008 was 4.55 in the range of the values between 1 and 9.The survey indicated that,under the influence of the major factors such as the worsened international economic situations,the evident decline of the demand for export and the quite big inflationary pressure,etc,the economists had shown evidently deeper concem over the economic trend.展开更多
NIM-Sr2 optical lattice clock has been developed on the Changping campus of National Institute of Metrology(NIM).Considering the limitations in NIM-Sr1,several improved parts have been designed including a differentia...NIM-Sr2 optical lattice clock has been developed on the Changping campus of National Institute of Metrology(NIM).Considering the limitations in NIM-Sr1,several improved parts have been designed including a differential pumping stage in the vacuum system,a permanent magnet Zeeman slower,water-cooled anti-Helmholtz coils,an extended viewport for Zeeman slower,etc.A clock laser with a short-time stability better than 3×10^(-16)is realized based on a self-designed 30-cm-long ultra-low expansion cavity.The systematic frequency shift has been evaluated to an uncertainty of 7.2×10^(-18),with the uncertainty of BBR shift and the collisional frequency shift being an order of magnitude lower than the last evaluation of NIM-Sr1.展开更多
Cuticular wax formation on the surface of plant leaves is associated with drought-stress tolerance.The identification of wax biosynthesis-related genes will contribute to the genetic improvement of drought resistance ...Cuticular wax formation on the surface of plant leaves is associated with drought-stress tolerance.The identification of wax biosynthesis-related genes will contribute to the genetic improvement of drought resistance in plants.In this study,we characterize a novel Dianthus spiculifolius mutant with increased cuticular wax.The mutant exhibited stronger drought resistance as indicated by less leaf wilting and death,higher leaf relative water content and water retention capacity,and slower water loss and chlorophyll extraction than did the wild type during drought treatment.In the mutant leaves,2730 upregulated and 2151 downregulated differentially expressed genes(DEGs)were identified by transcriptome sequencing.A wax biosynthesis pathway of the identified DEGs was significantly enriched.Finally,three key genes(DsCER1,DsMAH1,and DsWSD1)involved in wax biosynthesis were identified and verified by qPCR.These results suggest that differential expression of DEGs involved in wax biosynthesis may be associated with the increase in cuticular wax in the mutant.Taken together,our results help elucidate wax formation patterns in D.spiculifolius.Furthermore,the DEGs involved in wax biosynthesis identified here may be valuable genetic resources for improving plant stress tolerance through increased accumulation of cuticular wax.展开更多
Clinical outcomes are positively associated with hematoma absorption.The monocyte-macrophage scavenger receptor,CD163,plays an important role in the metabolism of hemoglobin,and a soluble form of CD163 is present in p...Clinical outcomes are positively associated with hematoma absorption.The monocyte-macrophage scavenger receptor,CD163,plays an important role in the metabolism of hemoglobin,and a soluble form of CD163 is present in plasma and other tissue fluids;therefore,we speculated that serum CD163 affects hematoma absorption after intracerebral hemorrhage.Patients with intracerebral hemorrhage were divided into high-and low-level groups according to the average CD163 level（1,977.79 ± 832.91 ng/m L）.Compared with the high-level group,the low-level group had a significantly slower hematoma absorption rate,and significantly increased National Institutes of Health Stroke Scale scores and modified Rankin Scale scores.These results suggest that CD163 promotes hematoma absorption and the recovery of neurological function in patients with intracerebral hemorrhage.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.51578464 and 71473207)China Fundamental Research Funds for Central Universities(Grant No.2682016cx082)
文摘A group of competitive people escaping through an exit could lead to the formation of a deadlock, which significantly increases the evacuation time. Such a phenomenon is called the faster-is-slower effect（FIS） and it has been experimentally verified in different systems of particles flowing through an opening. In this paper, the numerical simulation based on discrete element method（DEM） is adopted to study a group of highly competitive people through an exit of varying widths. The FIS effect is observed for a narrow exit whilst it is not observed for the exit wide enough to accommodate two people through it side-by-side. Experimental validation of such a phenomenon with humans is difficult due to ethical issues. The mouse is a kind of self-driven and soft-body creature and it exhibits selfish behaviour under stressed conditions.Particles flowing through an opening in different systems, such as pedestrian flow, animal flow, silo flow, etc. have similar characteristics. Therefore, experimental study is conducted by driving mice to escape through an exit of different widths at varying levels of stimulus. The escape time through a narrow exit（i.e., 2 cm） increases obviously with the increase of stimulus level but it is quite opposite to a wider exit（i.e., 4 cm）. The FIS effect is avoided for an exit wide enough to accommodate two mice passing through it side-by-side. The study illustrates that FIF effect could be effectively prevented for an exit when its width is twice the size of particles.
基金Project supported by the National Key Basic Research and Development Program of China(Grant Nos.2012CB821302 and 2016YFA0302103)the National Natural Science Foundation of China(Grant No.11134003)+1 种基金the National High Technology Research and Development Program of China(Grant No.2014AA123401)the Shanghai Excellent Academic Leaders Program of China(Grant No.12XD1402400)
文摘We develop a permanent-magnet Zeeman slower with adjustable magnets along the longitudinal and radial directions.Produced by four arrays of cylindrical magnets, the longitudinal magnetic field in the slower is tunable if relevant parameters vary, for example, laser detuning or intensity. The proposed Zeeman slower can be reconfigured for Sr atoms. Additionally,we demonstrate that the residual magnetic field produced by the permanent magnets in the magneto-optical trap region can be as small as 0.5 Gs.
基金Supported by the National Natural Science Foundation of China under Grant No 91336212
文摘We report a longitudinal Zeeman slower based on ring-shaped permanent magnetic dipoles used for the strontium optical lattice clock. The Zeeman slower is composed of 40 permanent magnets with the same outer diameter but different inner diameters. The maximum variation of the axial field from its target values is less than 2%. In most parts of the Zeeman slower, the intensity variations of the field in radial spatial distribution are less than 0.1 roT. With this Zeeman slower, the strontium atoms are slowed down to 95m/s, and approximately 2% of the total atoms are slowed down to less than 50m/s.
文摘Background: Women are thought to be more susceptible to stress than men in a stressful society, and reducing stress is crucial for women to maintain their health. Static stretching (SST) is applied in various fields to not only increase muscle flexibility but also reduce stress. Additionally, conscious slower breathing (CSB) predominates parasympathetic activity, causing a relaxing effect. These results indicate that combining SST and CSB may be more useful in reducing stress. However, to the best of our knowledge, the effect of this combination remains unclear. Objective: This study aimed to elucidate the effects of the combination of SST and CSB on autonomic activity and stress in adult women. Methods: Eleven healthy Japanese adult female participants performed SST with nonconscious natural breathing for 20 min. The same participants performed SST in combination with CSB (2 s inspiratory and 4 s expiratory) for 20 min on another day. Salivary cortisol and chromogranin A levels were measured before and after stretching as stress markers of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system. The coefficient of variation of the R-R interval (CVR-R) and high-frequency component (HF), which reflect parasympathetic nerve activity, and heart rate and low-frequency component (LF)/HF ratio, which reflect sympathetic nerve activity, were measured before, during, and after stretching. Results: SST decreased cortisol levels but with no significant changes in chromogranin A, heart rate, CVR-R, HF, or LF/HF ratio. The combination of SST and CSB increased CVR-R and HF levels in addition to decreasing cortisol levels but with no significant changes in chromogranin A, heart rate, or LF/HF levels. Conclusion: These results indicate that the combination of SST and CSB may increase parasympathetic activity and reduce stress. However, future randomized controlled trials with larger sample sizes should support this conclusion.
文摘Chinese outdoor industry is eyeing expansion in the future 10 years though its growth slows a little bit in recent years.China Outdoor Industry Report,released by China Outdoor Association(COA for short) at the Asia Outdoor 2015 held in Nanjing,capital of Jiangsu Province in July,shows that the outdoor core market volume in 2014 reached RMB 17.06
文摘On Sept. 26, Chana Auto announced that by Sept. 23, after several rounds of selling-off which started at the beginning of 2002, Suzuki’s B shares in Chana, the second largest holding, were reduced to 61.4 million from previous 122.5 million, accounting for only 5.003% of the whole. Some experts analyze there are two reasons behind the selling-off of Suzuki’s B shares of Chana: 1. Chana has been active recently in its cooperation with Ford (The initial investment of Chana Ford
文摘China National Textile & Apparel Council released the latest industry reviews in its mid-year conference that in the first half of 2010,the textile industry kept its stable recovery and the whole situation was good;for the anticipation of late half,this industry would continue this tendency but growth speed might slow down.
文摘As shown in the results of 100 Chinese Economists’ Confi- dence Survey,conducted by China’s Economic Monitoring and Analy- sis Center,National Bureau of Statistics,the confidence index of the economists in the second quarter of 2008 was 4.55 in the range of the values between 1 and 9.The survey indicated that,under the influence of the major factors such as the worsened international economic situations,the evident decline of the demand for export and the quite big inflationary pressure,etc,the economists had shown evidently deeper concem over the economic trend.
基金supported by the National Key R&D Program of China(Grant Nos.2021YFF0603802 and 2016YFF0200201)。
文摘NIM-Sr2 optical lattice clock has been developed on the Changping campus of National Institute of Metrology(NIM).Considering the limitations in NIM-Sr1,several improved parts have been designed including a differential pumping stage in the vacuum system,a permanent magnet Zeeman slower,water-cooled anti-Helmholtz coils,an extended viewport for Zeeman slower,etc.A clock laser with a short-time stability better than 3×10^(-16)is realized based on a self-designed 30-cm-long ultra-low expansion cavity.The systematic frequency shift has been evaluated to an uncertainty of 7.2×10^(-18),with the uncertainty of BBR shift and the collisional frequency shift being an order of magnitude lower than the last evaluation of NIM-Sr1.
基金This work was supported by grants from the Natural Science Foundation of Heilongjiang Province of China,no.C2016024the China Postdoctoral Science Foundation,no.2016M601409+1 种基金the Heilongjiang Postdoctoral Fund to Pursue Scientific Research in Heilongjiang Province of China,no.LBH-Z16024the Young Talent Project of Northeast Agricultural University of China,no.16QC06.
文摘Cuticular wax formation on the surface of plant leaves is associated with drought-stress tolerance.The identification of wax biosynthesis-related genes will contribute to the genetic improvement of drought resistance in plants.In this study,we characterize a novel Dianthus spiculifolius mutant with increased cuticular wax.The mutant exhibited stronger drought resistance as indicated by less leaf wilting and death,higher leaf relative water content and water retention capacity,and slower water loss and chlorophyll extraction than did the wild type during drought treatment.In the mutant leaves,2730 upregulated and 2151 downregulated differentially expressed genes(DEGs)were identified by transcriptome sequencing.A wax biosynthesis pathway of the identified DEGs was significantly enriched.Finally,three key genes(DsCER1,DsMAH1,and DsWSD1)involved in wax biosynthesis were identified and verified by qPCR.These results suggest that differential expression of DEGs involved in wax biosynthesis may be associated with the increase in cuticular wax in the mutant.Taken together,our results help elucidate wax formation patterns in D.spiculifolius.Furthermore,the DEGs involved in wax biosynthesis identified here may be valuable genetic resources for improving plant stress tolerance through increased accumulation of cuticular wax.
文摘Clinical outcomes are positively associated with hematoma absorption.The monocyte-macrophage scavenger receptor,CD163,plays an important role in the metabolism of hemoglobin,and a soluble form of CD163 is present in plasma and other tissue fluids;therefore,we speculated that serum CD163 affects hematoma absorption after intracerebral hemorrhage.Patients with intracerebral hemorrhage were divided into high-and low-level groups according to the average CD163 level（1,977.79 ± 832.91 ng/m L）.Compared with the high-level group,the low-level group had a significantly slower hematoma absorption rate,and significantly increased National Institutes of Health Stroke Scale scores and modified Rankin Scale scores.These results suggest that CD163 promotes hematoma absorption and the recovery of neurological function in patients with intracerebral hemorrhage.
