We reviewed the series of articles on the transdiagnostic sleep and circadian intervention(Tran S-C)for adolescents,including Harvey et al.'s randomized controlled trial(RCT)[1],Dong et al.'s 6-month follow-up...We reviewed the series of articles on the transdiagnostic sleep and circadian intervention(Tran S-C)for adolescents,including Harvey et al.'s randomized controlled trial(RCT)[1],Dong et al.'s 6-month follow-up[2],Dolsen et al.'s 1-year follow-up[3],and Susman et al.'s 8-year follow-up[4].The results indicated that Tran S-C had an effect trajectory:"significant short-term improvement–partial maintenance at 6 months–stability of core indicators+text messaging intervention reinforcement at 1 year-effect attenuation at 8 years.”展开更多
Cancer-related fatigue is the most prevalent and persistently symptom in cancer survivors than any other symptom,which is caused by both the disease and its treatment.Patients with cancer show a severe symptom of fati...Cancer-related fatigue is the most prevalent and persistently symptom in cancer survivors than any other symptom,which is caused by both the disease and its treatment.Patients with cancer show a severe symptom of fatigue,which cannot be relieved by general rest or sleep.Cancer-related fatigue negatively impacts a patient's physical and emotional function,social ability and even patients’prognosis.At present,the mechanism of cancer-related fatigue remain unclear despite much research,and a variety of mechanisms may contribute to its occurrence and development,including inflammatory reaction,metabolism dysregulation,immune activation,hormonal changes,central nervous system dysfunction,etc.Now a broad variety of drugs and non-drugs interventions are used against cancer-related fatigue.The intervention of conventional western medicine mainly contains hematopoietic stimulants,hormones,mental stimulants,and antidepressants,but their widely clinical application is limited by their effectiveness and possible side effects to a certain degree.There are also many forms of non-drug interventions for managing cancer-related fatigue,such as exercise intervention,psychological intervention,sleep intervention,nutrition intervention,bright white light therapy,etc.The aim of this review is to provide recommendations of non-drug interventions for patients with CRF during and after cancer treatment,in order to provide an evidence-based guideline for clinicians.展开更多
基金supported by the National Key Research and Development Program[grant number 2022YFC2503902,for Cheng-Mei Yuan],the Integrated Innovation Team of Shanghai Mental Health Center。
文摘We reviewed the series of articles on the transdiagnostic sleep and circadian intervention(Tran S-C)for adolescents,including Harvey et al.'s randomized controlled trial(RCT)[1],Dong et al.'s 6-month follow-up[2],Dolsen et al.'s 1-year follow-up[3],and Susman et al.'s 8-year follow-up[4].The results indicated that Tran S-C had an effect trajectory:"significant short-term improvement–partial maintenance at 6 months–stability of core indicators+text messaging intervention reinforcement at 1 year-effect attenuation at 8 years.”
文摘Cancer-related fatigue is the most prevalent and persistently symptom in cancer survivors than any other symptom,which is caused by both the disease and its treatment.Patients with cancer show a severe symptom of fatigue,which cannot be relieved by general rest or sleep.Cancer-related fatigue negatively impacts a patient's physical and emotional function,social ability and even patients’prognosis.At present,the mechanism of cancer-related fatigue remain unclear despite much research,and a variety of mechanisms may contribute to its occurrence and development,including inflammatory reaction,metabolism dysregulation,immune activation,hormonal changes,central nervous system dysfunction,etc.Now a broad variety of drugs and non-drugs interventions are used against cancer-related fatigue.The intervention of conventional western medicine mainly contains hematopoietic stimulants,hormones,mental stimulants,and antidepressants,but their widely clinical application is limited by their effectiveness and possible side effects to a certain degree.There are also many forms of non-drug interventions for managing cancer-related fatigue,such as exercise intervention,psychological intervention,sleep intervention,nutrition intervention,bright white light therapy,etc.The aim of this review is to provide recommendations of non-drug interventions for patients with CRF during and after cancer treatment,in order to provide an evidence-based guideline for clinicians.
